ライフサイエンスコーパス: endogenous antigen

1 ble in most cell types due to the paucity of endogenous antigen.

2 of Ii and DM and will preferentially present endogenous antigen.

3 he TAP complex for efficient presentation of endogenous antigen.

4 (NAbs) have been associated with exposure to endogenous antigens.

5 ng MAIT cells to sample both endocytosed and endogenous antigens.

6 les that display peptides from exogenous and endogenous antigens.

7 he stimulation of CD4+ T-cell responses from endogenous antigens.

8 ntigens, while promoting the presentation of endogenous antigens.

9 ansgenic OTII mice that lack specificity for endogenous antigens.

10 processing and presentation of exogenous and endogenous antigen and are largely maturationally synchr

11 sphoprotein 65 (HCMVpp65)(422-439) mimics an endogenous antigen and initiates lupus-like autoimmunity

12 face antigen presentation of transfected and endogenous antigens and enhance cytotoxic T-cell respons

13 by compatibility with 28 antibodies to both endogenous antigens and transgenic reporters like GFP.

14 s) induce GrB(+)CD8(+) T cells by presenting endogenous antigens and using the 4-1BBL/4-1BB axis.

15 lls from mounting inappropriate responses to endogenous antigens, and place recent work into historic

16 unogen and the immunogenicity of the related endogenous antigen are important in determining the spec

17 at restrain B cell responses to low-affinity endogenous antigens are not fully understood.

18 However, other endogenous antigens are processed by cytoplasmic proteas

19 cells into lymphopenic mice that express an endogenous antigen as a systemic, secreted protein resul

20 in naive mice antigen-specific CTLs against endogenous antigens as well as exogenous peptides, but n

21 Class I MHC protein primarily presents endogenous antigen but also may present exogenous antige

22 imulating cellular immunity, presentation of endogenous antigens by dendritic cells transfected with

23 ity was also dispensable for presentation of endogenous antigens by MHC-I via the classical pathway.

24 The failure of T134K to present endogenous antigen can be overcome by using an ER target

25 lytic effector function and the finding that endogenous antigens can enter the HLA class II processin

26 ntigen uptake or presentation, the source of endogenous antigen, costimulatory molecules or peptides

27 nant populations that efficiently recognized endogenous antigen demonstrated lower intrinsic avidity

28 T cells that respond to this endogenous antigen develop into effector cells that caus

29 de epitopes, we have successfully created an endogenous, antigen-driven mouse model that ensures a co

30 t can effectively prime T cells specific for endogenous antigens expressed by poorly immunogenic tumo

31 and drugs or viral infections and, perhaps, endogenous antigens generated by genetically altered bon

32 Expression of HLA class II and endogenous antigen, however, does not always correlate w

33 ulated expression of H2 molecules presenting endogenous antigen in the peritoneal mesothelium and ves

34 model system to study the immunogenicity of endogenous antigens in adult animals.

35 alpha-galactosylceramide (alpha-galcer) and endogenous antigens in mouse splenic and bone marrow-der

36 Of the 10 clones, 3 responded to endogenous antigens in rat islets.

37 e of mature PDCs in priming CD8 responses to endogenous antigens, in addition to their previously rep

38 ass II-restricted surveillance of long-lived endogenous antigens including nuclear proteins relevant

39 antigenic epitopes derived from exogenous or endogenous antigens is altered in PA28-/- mice.

40 C cytoskeleton of the sizes and densities of endogenous antigen-loaded CD1d nanoclusters.

41 levant antigen-specific CTLs that recognized endogenous antigen-major histocompatibility complex comp

42 an absolute requirement for presentation of endogenous antigen on Ld or for induction of virus-speci

43 protein A-luciferase (SPA-luc) was bound to endogenous antigens on primary human bronchial epithelia

44 We hypothesized that constantly degraded endogenous antigen only accumulates upon inhibition of a

45 ent and specific T-cell response against the endogenous antigen or self-antigen still remains a major

46 Enhanced autophagy boosts endogenous antigen presentation by MHC II and allows hos

47 In this study, we define a mechanism of endogenous antigen presentation by MR1 to MAIT cells.

48 vaccine cells present tumor peptides via the endogenous antigen presentation pathway to activate CD4(

49 antigen processing, utilizing the classical endogenous antigen presentation pathway.

50 rriers of the cancer immunity cycle, such as endogenous antigen presentation, immune priming, and nat

51 otein involved in the MHC class I pathway of endogenous antigen presentation.

52 egy for systematically learning the rules of endogenous antigen presentation.

53 fer of cellular material from vaccine DCs to endogenous antigen presenting cells was visualized in ly

54 eptide-MHC, both of which are available from endogenous antigen-presenting cells (APC), we hypothesiz

55 of antigen from antigen-specific B cells to endogenous antigen-presenting cells or by direct B-T cel

56 Finally, endogenous antigen-primed CD4(+) T cells responded equiv

57 st, the contribution of proteasome-dependent endogenous antigen processing to the global influenza CD

58 Although several endogenous antigen-processing pathways have been reporte

59 resolution of recombination intermediates in endogenous antigen receptor loci.

60 AG2 C terminus in mediating rearrangement of endogenous antigen-receptor loci.

61 e follicular B cells tunes responsiveness to endogenous antigen recognition, and discuss how this may

62 The ability of iNKT cells to recognize endogenous antigens represents a distinct immune recogni

63 has not yet been resolved if there is single endogenous antigen responsible for both positive selecti

64 en masse, thereby reducing participation by endogenous antigen-specific B cells in T-dependent humor

65 bsets in the skin and monitor the effects on endogenous antigen-specific CD4(+) T- and B-cell respons

66 in substantial expansion and maintenance of endogenous antigen-specific CD8 T cells.

67 n activation and expansion of both donor and endogenous antigen-specific cells in a dose-dependent ma

68 tions; however, the inability to detect rare endogenous antigen-specific cells limits current underst

69 tramers to track and analyze a population of endogenous antigen-specific memory CD4 T cells exposed t

70 eoantigens in mice would enable the study of endogenous antigen-specific naive T cell responses in di

71 oduce FucoID as a general platform to detect endogenous antigen-specific T cells for studying their b

72 een two relatively rare populations-DTCs and endogenous antigen-specific T cells-underlies DTC persis

73 e mast cell contribution to the induction of endogenous, antigen-specific CD4(+) T cells.

74 suppression by polyclonal T regs depends on endogenous antigen stimulation; this occurs in a locatio

75 cells (DCs) sample and process exogenous and endogenous antigens that can trigger an inflammatory nid

76 hi dendritic cells (DCs) efficiently present endogenous antigen to activate naive PLP139-151-specific

77 US6 transfected cells are unable to present endogenous antigen to cytotoxic T lymphocytes and are th

78 ged to lysine (T134K), are unable to present endogenous antigens to CTLs.

79 lack this transporter are unable to present endogenous antigens to CTLs.

80 Typically, MHC class I molecules present endogenous antigens to cytotoxic T lymphocytes (CTLs).

81 Antigen presentation of endogenous antigens was required to develop cardiac dysf

82 ighly immunogenic and preferentially present endogenous antigens, while tumors coexpressing class II

83 The autoimmunity appears to be driven by endogenous antigens, with little polyclonal B cell activ