ライフサイエンスコーパス: endomembrane

1 t) was also constructed with markers for the endomembrane.

2 f phosphatidylserine from plasma membrane to endomembrane.

3 th independently localized to the same yeast endomembrane.

4 ein associated with both plasma membrane and endomembranes.

5 ylate mislocalized palmitoylated proteins on endomembranes.

6 t virus viability depends on functional host endomembranes.

7 o recruitment and phosphorylation of eNOS at endomembranes.

8 nal and morphological integrity of the plant endomembranes.

9 ne tubules emanating from these disorganized endomembranes.

10 rounded by a reservoir of the recruited host endomembranes.

11 contributes to dynactin's interactions with endomembranes.

12 dy complex and dynamic systems such as plant endomembranes.

13 d; however, less is known about transport at endomembranes.

14 uttling, G proteins constitutively reside in endomembranes.

15 mily translocate specifically from the PM to endomembranes.

16 ivate VRACs, and VRACs were not activated on endomembranes.

17 h direct communication between receptors and endomembranes.

18 the actin cytoskeleton and actin-associated endomembranes.

19 ccumulates in the nucleus, chloroplasts, and endomembranes.

20 e place of SNARE assembly and thus fusion at endomembranes.

21 of Cu(+) across both the plasma membrane and endomembranes.

22 1, ULK1, and Beclin 1 in response to damaged endomembranes.

23 4,5)P2 hydrolysis with carrier biogenesis on endomembranes.

24 targeting sequence resulted in enhanced RalB endomembrane accumulation and decreased RalB association

25 d plants expressing a PIN2GFP fusion exhibit endomembrane accumulation of PIN2GFP, but no changes in

26 s through the remodeling cycle to modify the endomembrane and facilitate formation of the replication

27 we analyzed Cdc42, which concentrates in the endomembrane and has been shown to act downstream of Ras

28 and K-Ras4B from the plasma membrane to the endomembrane and inhibits their nanoclustering.

29 Microtubule-based endomembrane and organelle motility utilizing the motor

30 n each region, many neuronal profiles showed endomembrane and plasmalemmal distributions of one or bo

31 s Ras proteins to interact with Cdc42 on the endomembrane and that in order for a given Ras protein t

32 e danger receptor galectin-8 detects damaged endomembranes and activates autophagy through recruitmen

33 ains of the plasma membrane as well as other endomembranes and are capable of generating distinct sig

34 Sphingolipids are structural components of endomembranes and function through their metabolites as

35 that these pollen grains contained aberrant endomembranes and lacked an intine layer.

36 eins traffic between the plasma membrane and endomembranes and signal from the cytosolic face of a va

37 ion and its aberrant activation in the Golgi endomembranes and suggest that non-canonical interaction

38 PA reporter showed differential labeling of endomembranes and the PAM.

39 ary and sufficient to remodel host actin and endomembranes and to recruit TGB2/3 to the X-body, thus

40 the combined activities of the cytoskeleton, endomembrane, and cell wall biosynthetic systems organiz

41 er, H-Ras formed a complex with Cdc42 on the endomembrane, and this interaction was enhanced when H-R

42 ajor component of plant plasma membranes and endomembranes, and mediate a diverse range of biological

43 localize to the plasma membrane rather than endomembranes, and rather than hydrolyzing PPi to create

44 lying the organization and dynamics of plant endomembranes are largely unknown.

45 ecruited on LC3B-positive 'autophagy-related endomembranes' (ARE).

46 h tumor necrosis factor-alpha activated only endomembrane-associated Chp.

47 1) receptors localized in close proximity to endomembrane-associated trimeric G protein and adenylyl

48 ne were sufficient to promote Chp plasma and endomembrane association.

49 e been identified, little is known about the endomembrane-based transport of glycan components.

50 es the rate of phospholipid biosynthesis and endomembrane biogenesis to cell cycle progression in Ara

51 Coordination of endomembrane biogenesis with cell cycle progression is c

52 rees of altered movement of RAB2:GFP-labeled endomembrane bodies were used to generate a training set

53 ven by myosin motors dragging organelles and endomembrane-bounded cargo along actin filament bundles.

54 pids and acyl chains resemble those of other endomembranes, bundle ceramide and sphingomyelin nearly

55 genic H-Ras mutant that is restricted to the endomembrane can still transform cells.

56 which myosin XI-K attaches to its principal endomembrane cargo, a yeast two-hybrid library of Arabid

57 bidopsis (Arabidopsis thaliana), a family of endomembrane cation exchangers (CAXs) transports Ca(2+)

58 ity can be controlled solely by manipulating endomembrane cation flux capacities.

59 ression enhanced recruitment of alsin to the endomembrane compartment in glial cells, suggesting that

60 st a panel of plasma membrane (PM) and other endomembrane compartment markers to identify molecules t

61 e to membrane-associated functions; however, endomembrane compartmentalization and endocytosis/exocyt

62 TFL1 localizes to endomembrane compartments and colocalizes with the putat

63 s define a trafficking pathway with specific endomembrane compartments and polar auxin transport prot

64 t uncovered this link between small RNAs and endomembrane compartments and present an overview of the

65 dopsis thaliana, are associated with diverse endomembrane compartments and tissues in plants, althoug

66 ansporters that alter the environment across endomembrane compartments are thought to be important pl

67 brassinosteroid receptor BRI1 into distinct endomembrane compartments termed "endosidin bodies"; how

68 to redistribute from the plasma membrane to endomembrane compartments, dissociated R7BP-bound R7 RGS

69 e activity are avirulent and fail to acidify endomembrane compartments, exhibiting pleiotropic defect

70 eciation that G proteins are also present at endomembrane compartments, where they can potentially in

71 that operate from both the cell surface and endomembrane compartments.

72 hat both Vnx1 and Cax1 proteins are found in endomembrane compartments.

73 endocytosis followed by trafficking to deep endomembrane compartments.

74 free of significant contamination from other endomembrane compartments.

75 y plasma membrane (PM)-localized PEN3-GFP in endomembrane compartments.

76 ssing, sorting and trafficking to subsequent endomembrane compartments.

77 cted, EXOSC10-depleted oocytes have impaired endomembrane components including endosomes, lysosomes,

78 ter is required to sustain metallation of an endomembrane cuproenzyme, providing a mechanism for exqu

79 Endomembrane cuproproteins are thought to incorporate co

80 It can be loaded onto secreted and endomembrane cuproproteins by translocation from the cyt

81 Endomembrane damage elicits homeostatic responses includ

82 macrophages by pathogen- or sterile-induced endomembrane damage.

83 We demonstrate for the first time that endomembrane-delimited H-Ras mediates VEGF-induced activ

84 ully restored by modest overexpression of an endomembrane-delimited H-Ras palmitoylation mutant.

85 achieved using combinations of heterologous endomembrane desaturases and elongases expressed in mode

86 s the palmitoylation cycle controlling GAD65 endomembrane distribution, resulting in aberrant accumul

87 r contributions to H-Ras plasma membrane and endomembrane distribution.

88 dicating that autophagy triggered by damaged endomembranes during the entry of assembled tau seeds pr

89 esolved to scaffold Rab GTPases and regulate endomembrane dynamics in an isoform-specific manner.

90 Phox (PX) domain-containing protein Mdm1 in endomembrane dynamics.

91 a global fluorescence-based screen to reveal endomembrane effector genes.

92 sion structure, by remodeling host actin and endomembranes (endoplasmic reticulum and Golgi).

93 in inhibition of proliferation and defective endomembrane expansion and reduced expression of CD138 a

94 ous PtdInsP kinase activity increased in the endomembrane fraction of hyperosmotically stressed cells

95 from the plasma membrane to a lower phase or endomembrane fraction.

96 Biochemical characterization of endomembrane fractions from vnx1 mutant cells and zebraf

97 ogether, our results show that Dw2 modulates endomembrane function and cell division during sorghum i

98 ere annotated in three broad categories: (1) endomembrane function, containing p.Phe508del processing

99 f actin filaments that controls a variety of endomembrane functions including the endocytic internali

100 into the role of Asna1/TRC40 in maintaining endomembrane homeostasis and beta-cell function, we inac

101 nverge to activate AMPK and autophagy during endomembrane homeostasis.

102 The M2R was localized to endomembranes in DAT-containing somatodendritic profiles

103 suggests that TRPV1 receptors also reside on endomembranes in neurons and can mediate Ca(2+) release

104 ged AtCCX3 fusion proteins were localized to endomembranes in plants and yeast.

105 owth factor receptor alpha to LAMP2-positive endomembranes in the absence of ligand, suggesting that

106 Dynamic intracellular of endomembranes, in combination with increased velocity an

107 ectrin-based cytoskeleton is associated with endomembranes, including the Golgi complex and cytoplasm

108 dings reveal an essential role for the plant endomembrane, independent of secretion, in the intercell

109 Our results reveal that by monitoring endomembrane integrity, cells reduce entry of tau seeds

110 In a proteomic screen for endomembrane interactants of the RING-domain E3 ligase,

111 ependent endocytosis and escape from damaged endomembranes into the cytosol, where they seed the aggr

112 The pH homeostasis of endomembranes is essential for cellular functions.

113 cant increase in p47(phox) immunolabeling on endomembranes just beneath the plasmalemmal surface (+42

114 2-mediated lysine defatty-acylation promotes endomembrane localization of K-Ras4a, enhances its inter

115 ALA4-GFP displayed plasma membrane and endomembrane localization patterns when imaged in both g

116 in experiments aimed at defining nuclear or endomembrane localization.

117 subunit1) or ALIS5, leading to differential endomembrane localizations of the interacting proteins,

118 ry, these findings suggest that AtCCX3 is an endomembrane-localized H(+)-dependent K(+) transporter w

119 e studies define a newly recognized role for endomembrane-localized H-Ras in mediating nitric oxide-d

120 eaving the function of the large majority of endomembrane-localized H-Ras unexplained.

121 partments and mediates the ubiquitination of endomembrane-localized PHT1;1.

122 rotrimeric G proteins signal at a variety of endomembrane locations, in addition to their canonical f

123 e importance of NHX5 and NHX6 in maintaining endomembrane luminal pH and supports the notion that pro

124 the plasma membrane are tightly regulated by endomembrane machinery, especially the endocytic and rec

125 Similarly, crosses with other endomembrane marker fusions identified mislocalization t

126 Co-expression analyses of AtPIP2;1 with endomembrane markers revealed that H2O2 triggers AtPIP2;

127 th NEV-specific antiserum and a set of plant endomembrane markers revealed that NEV localizes to the

128 These findings also suggest that endomembranes may provide an obstacle to colocated trans

129 omes through plasmodesmata (PD) and use cell endomembranes, mostly the endoplasmic reticulum (ER), fo

130 r the application of GFP technology in plant endomembranes, namely optical tweezers and forward genet

131 ssary for proliferation and expansion of the endomembrane network in response to LPS.

132 Zika virus, extensively remodel the cellular endomembrane network to generate replication organelles

133 trand RNA viruses are known to rearrange the endomembrane network to make it more conducive for repli

134 Most RNA viruses remodel the endomembrane network to promote virus replication, matur

135 of a strategy to quantitatively dissect the endomembrane network.

136 about the topology and dynamics of PS in the endomembranes of normal cells.

137 of the plasma membrane, tonoplast, and other endomembranes of plant cells.

138 s1 mutants that are restricted to either the endomembrane or the plasma membrane.

139 lasm, or specifically affiliated with either endomembranes or large dense-core vesicles.

140 ockdown of the oxidase Nox4, expressed on ER endomembranes, or expression of ER-targeted catalase blo

141 ted in somata and dendrites, associated with endomembranes, or in dendritic spines.

142 Endomembrane organelle maturation requires cargo deliver

143 d in polysomes engaged in the translation of endomembrane organelle proteins, whereas translocon acce

144 e also able to measure the dynamics of PS in endomembrane organelles.

145 ehiscence, suggesting defects in vacuole and endomembrane organization.

146 lytic processing of storage proteins require endomembrane pH homeostasis.

147 quantitatively evaluate dynamic subcellular endomembrane phenotypes induced by bioactive chemicals,

148 or protein 1 (AP-1) complexes, which mediate endomembrane polarization, sorting, and transport.

149 We suggest that changes in endomembrane potential affect JA pathway activity.

150 increases in the surface-to-volume ratio of endomembranes promote traffic between compartments and h

151 position 80 to a leucine residue in a small endomembrane protein encoded by the gold36 locus (At1g54

152 AFL1 interacted with the endomembrane proteins protein disulfide isomerase 5 (PDI

153 In contrast, localization of endomembrane proteins was not altered.

154 in the biogenesis of thousands of eukaryotic endomembrane proteins.

155 adioisotopic electrodiffusion flux assays on endomembrane proteoliposomes suggested that *O(2)(-) and

156 To define downstream targets of endomembrane Ras pathways, we analyzed Cdc42, which conc

157 ator of signaling specificity functioning at endomembranes rather than at the plasma membrane.

158 membrane protein, known as 6K2, that induces endomembrane rearrangements for the formation of viral r

159 inhibition of mTORC1 activity abolishes both endomembrane reorganization and IL-8 secretion.

160 Our results indicate that the actin/endomembrane-reorganizing properties of TGB1 function to

161 Membrane fusion at endomembranes requires cross-talk between Rab GTPases an

162 mRNAs encoding endomembrane-resident proteins were bound via direct, ri

163 y, we demonstrated that cells transformed by endomembrane-restricted oncogenic H-Ras formed tumors in

164 ata show that cell transformation induced by endomembrane-restricted oncogenic H-Ras was blocked when

165 However, when examined in ras1 null cells, endomembrane-restricted Ras1 supported morphology but no

166 share a niche with lipid droplets within the endomembrane-secretory system.

167 rane Ca(2+) channels and Ca(2+) release from endomembrane stores coordinately elevate cytosolic free

168 ledge, the nuclear net is the most elaborate endomembrane structure described within a nucleus.

169 APM1 associates with brefeldin A-sensitive endomembrane structures and the plasma membrane in corti

170 type root tips, although PIN2 accumulates in endomembrane structures in pid-9 roots.

171 Archaea are prokaryotic organisms that lack endomembrane structures.

172 les within the different compartments of the endomembrane system and address their associated develop

173 TMEM127 dynamically associates with the endomembrane system and colocalizes with perinuclear (ac

174 like Rab8 to control trafficking through the endomembrane system and on to the cilium.

175 s that wax components are trafficked via the endomembrane system and packaged in Golgi-derived secret

176 d sphingolipids, are major components of the endomembrane system and plasma membrane in most eukaryot

177 1 to the outer mitochondrial membrane or the endomembrane system and show that PE can cross the IMS i

178 ing evidence reveals connections between the endomembrane system and small RNA activities in plants a

179 s revealed that MYR localized protein to the endomembrane system and that partitioning between this m

180 proteins with well-established roles in the endomembrane system and the process of transcription elo

181 complexes (CSCs), which are assembled in the endomembrane system and trafficked to the plasma membran

182 CTL1/POM1 coincided with CESAs in the endomembrane system and was secreted to the apoplast.

183 This endomembrane system arose and diversified during a perio

184 ed that AtGALT2 is probably localized in the endomembrane system consistent with its function.

185 Fusion of organelles in the endomembrane system depends on Rab GTPases that interact

186 Membrane fusion within the eukaryotic endomembrane system depends on the initial recognition o

187 The plant endomembrane system facilitates the transport of polysac

188 proteins initiate their journey through the endomembrane system from specific subdomains of the endo

189 ith green fluorescent protein markers of the endomembrane system in Arabidopsis seedlings, we show th

190 the final site of protein deposition in the endomembrane system in developing rice endosperm.

191 the evolutionary forces that have shaped the endomembrane system in eukaryotes and highlights ways in

192 uxes and possibly pH modulation of an active endomembrane system in guard cells.

193 motor that transports cargo vesicles of the endomembrane system in intracellular recycling pathways.

194 The endomembrane system in plant-microbe interactions 1013 I

195 s, yet little is known about the role of the endomembrane system in this process.

196 resent an overview of the involvement of the endomembrane system in various aspects of RNA silencing.

197 m of PAP is targeted to the cytosol from the endomembrane system in yeast.

198 nt provokes a profound reorganization of the endomembrane system into foci containing double membrane

199 We propose that the endomembrane system is an integral component of RNA sile

200 The eukaryotic endomembrane system is controlled by small GTPases of th

201 der to provide direct pH measurements in the endomembrane system lumen, we targeted genetically encod

202 Organelles of the endomembrane system maintain their identity and integrit

203 The identity of organelles in the endomembrane system of any eukaryotic cell critically de

204 O](51):GalT activities were localized to the endomembrane system of Arabidopsis suspension-cultured c

205 proton-pumping vacuolar ATPase found in the endomembrane system of eukaryotes.

206 The endomembrane system of eukaryotic cells uses membrane-en

207 ex family involved in protein sorting in the endomembrane system of eukaryotic cells.

208 sm for the transport of proteins through the endomembrane system of plants.

209 cycling pectin methylesterase enzymes in the endomembrane system of seed coat epidermal cells.

210 Turnip mosaic virus (TuMV) reorganizes the endomembrane system of the infected cell to generate end

211 The endomembrane system plays essential roles in plant devel

212 that, during organogenesis, the Arabidopsis endomembrane system specifies an important additional ce

213 llmark of the eukaryotic cell is the complex endomembrane system that compartmentalizes cellular func

214 our study illustrates the plasticity of the endomembrane system through TRAPP protein functions and

215 Enveloped viruses exploit the endomembrane system to enter host cells.

216 hough viruses must navigate the complex host endomembrane system to infect cells, the strategies used

217 in growing oocytes and traffics through the endomembrane system to the cell surface, where it is rel

218 internalized by activated neutrophils in the endomembrane system via 12(S)-HETE.

219 ancestors, secretion of material through the endomembrane system was the major mechanism for interact

220 mRNAs encoding resident proteins of the endomembrane system were clustered at high ER-enrichment

221 ed that most stickling differences involved "endomembrane system" (PICALM, STX4, and LRP10), "hydrola

222 Cs) and nuclear membranes coevolved with the endomembrane system, and that the last eukaryotic common

223 some eukaryotic organelles, for example the endomembrane system, evolved without endosymbiotic input

224 ntry, viruses must navigate through the host endomembrane system, penetrate cellular membranes, and u

225 protein even though these organisms have no endomembrane system, suggesting that the Vps4/ESCRT-III

226 s in sorting protein constituents within the endomembrane system.

227 equires proper ion and pH homeostasis of the endomembrane system.

228 ing mutants that trap secretory cargo in the endomembrane system.

229 somes are unique among the organelles of the endomembrane system.

230 Gemmata obscuriglobus possesses an extensive endomembrane system.

231 dditional insights into the sculpting of the endomembrane system.

232 components of the plant plasma membrane and endomembrane system.

233 fission dynamics may be conserved within the endomembrane system.

234 exes are required for membrane fusion in the endomembrane system.

235 lic proteins that tend to associate with the endomembrane system.

236 bolic energy, and the building blocks of the endomembrane system.

237 sses, responses to (a)biotic stress, and the endomembrane system.

238 rt of pistil ECM proteins in the pollen tube endomembrane system.

239 vironment, and predominantly localize to the endomembrane system.

240 the channel was sensitive to disrupting the endomembrane system.

241 egradative (i.e., catabolic) branches of the endomembrane system.

242 trol systems to structure and coordinate the endomembrane system.

243 n on epidermal cells and organization of the endomembrane system.

244 itochondria are indeed integrated within the endomembrane system.

245 is enriched for functions related to diverse endomembrane systems and their organization.

246 Mitochondria are one of the major ancient endomembrane systems in eukaryotic cells.

247 istributed along cytoplasmic tubulovesicular endomembrane systems in somata and large dendrites, but

248 lein revealed alterations of the presynaptic endomembrane systems similar to our findings in cell cul

249 lutionarily highly conserved and fundamental endomembrane systems.

250 ysosomal fusion capacity and accumulation of endomembranes that accompanies PSEN deficiency.

251 ed transcription and translation, a role for endomembranes that has not been reported previously for

252 islocalization of GFP-RAB7 and GFP-RAB8 from endomembrane to cytosol, enhanced binding to RABGDI, and

253 energy to pump H(+) across the tonoplast and endomembranes to create proton motive force (pmf).

254 oplasmic surfaces of the plasma membrane and endomembranes to maintain G protein pools in intracellul

255 HO2 modulates the degradation of PHO1 in the endomembranes to maintain Pi homeostasis in plants.

256 ctors, auxin transport and response factors, endomembrane traffic components and other signaling path

257 e and membrane stability, cell polarity, and endomembrane traffic.

258 During polarized growth of pollen tubes, endomembrane trafficking and actin polymerization are tw

259 hored receptors (MyoB) that, together, drive endomembrane trafficking and cytoplasmic streaming in th

260 1/TRC40, is implicated in the maintenance of endomembrane trafficking and ER homeostasis.

261 the mRNAs that encode proteins important for endomembrane trafficking and meiotic cell cycle.

262 sults provide evidence of cross talk between endomembrane trafficking and the actin cytoskeleton in p

263 Disrupting endomembrane trafficking by BFA or wortmannin perturbed

264 tion during cytokinesis that does not affect endomembrane trafficking during interphase or cytoskelet

265 , their root cells display delayed actin and endomembrane trafficking dynamics and selectively secret

266 ) function as the central junction for major endomembrane trafficking events, including endocytosis a

267 rapidly elongating cells require tip-focused endomembrane trafficking for the deposition and recyclin

268 ved in various instances of clathrin-related endomembrane trafficking in plants.

269 screen to discover small molecules targeting endomembrane trafficking in vivo in a complex eukaryote,

270 n indirect effect, possibly due to perturbed endomembrane trafficking of certain membrane-localized s

271 trastructural evidence suggestive of somatic endomembrane trafficking of M2Rs, whose activation serve

272 trations of drugs that interfere with either endomembrane trafficking or the actin cytoskeleton, then

273 with markers of cellular compartments of the endomembrane trafficking pathway.

274 es auxin-mediated tissue differentiation and endomembrane trafficking pathways downstream of ribosoma

275 Endomembrane trafficking relies on the coordination of a

276 ins from key metabolic pathways and from the endomembrane trafficking systems associated with a free-

277 :H7 type III effector EspG as a regulator of endomembrane trafficking using a functional screen, and

278 eins involved in lipid signaling (PLDdelta), endomembrane trafficking, hormone, light, and receptor s

279 EACH-domain-containing protein implicated in endomembrane trafficking, is required for both electrica

280 anisms are thought to involve alterations in endomembrane trafficking, mitochondrial function, and li

281 lays a conserved role in organizing cellular endomembrane trafficking, required for delivery of defen

282 broad range of cellular processes including endomembrane trafficking, signaling, exocytosis and endo

283 (GTPase)-a protein previously implicated in endomembrane trafficking-as a regulator of the phosphati

284 nds that altered pollen tube development and endomembrane trafficking.

285 cytoskeleton was critical for some steps in endomembrane trafficking.

286 blished as biochemically distinct domains by endomembrane trafficking.

287 e latent oncogenic potential in dysregulated endomembrane trafficking.

288 on, recycling, or degradation by overviewing endomembrane trafficking; (2) discuss pathways regulatin

289 g cells is shown to match an interruption in endomembrane transport.

290 One endomembrane-type Ca-ATPase from Arabidopsis (Arabidopsi

291 d away from the growing bud, possibly to the endomembrane/vacuolar system.

292 accumulation of PtdIns(4,5)P(2) on aberrant endomembrane vacuoles, mislocalization of the cytokineti

293 wax export requires GNL1- and ECH-dependent endomembrane vesicle trafficking to deliver cargo to pla

294 N associated with PI3K-C2beta on a subset of endomembrane vesicles and enhanced both basal and growth

295 tition between the cytosolic pools of motile endomembrane vesicles that colocalize with myosin XI-K a

296 The BBN-conjugate partially localized in endomembrane vesicles that were associated with Rab7 or

297 les, including endoplasmic reticulum, Golgi, endomembrane vesicles, peroxisomes, and mitochondria.

298 Rheb is targeted to endomembranes via its C-terminal CAAX (C=cysteine, A=ali

299 y colocalized and physically interact in the endomembranes, where the ubiquitin conjugase activity of

300 The sphingolipid content varies among endomembranes with pre- and post-Golgi compartments bein