ライフサイエンスコーパス: endorphin

1 or lacking either pre-pro-enkephalin or beta-endorphin.

2 yloid fiber formed by the human hormone beta-endorphin.

3 ltered cleavage profile for the peptide beta-endorphin.

4 a-neoendorphin, but not endomorphins or beta-endorphin.

5 cyte-stimulating hormone (beta-MSH) and beta-endorphin.

6 beta-lipotropin to gamma-lipotropin and beta-endorphin.

7 in the level of C-terminally processed beta-endorphin.

8 sed for dual immunocytochemistry of Fos/beta-endorphin.

9 gh the post-translational processing of beta-endorphin.

10 MC), or PVN levels of Met-Enkephalin or beta-Endorphin.

11 beta-lipotropic hormone (beta LPH), and beta endorphin.

12 de Y, vasoactive intestinal peptide, or beta-endorphin.

13 ulating hormone, and the opioid peptide beta-endorphin.

14 acid decarboxylase 67 (GAD67), NPY, and beta-endorphin.

15 duced increases in nitrite, nitrate and beta-endorphin.

16 ate an NO-dependent neuronal release of beta-endorphin.

17 abolites nitrite and nitrate as well as beta-endorphin.

18 for their content of NO metabolites and beta-endorphin.

19 a against the endogenous opioid peptide beta-endorphin.

20 as methadone and endogenous opioids such as endorphins.

21 imulating hormone, beta-lipotrophin, and the endorphins.

22 s well as to endogenous peptide ligands like endorphins.

23 bital-anesthetized rats pretreated with beta-endorphin (0.5 nmol i.c.v.).

24 tidase which converts beta-endorphin to beta-endorphin 1-17 (gamma-endorphin), beta-endorphin 1-18, a

25 beta-endorphin 1-17 (gamma-endorphin), beta-endorphin 1-18, and their corresponding C-terminal fragm

26 ministration of morphine (1 microg) and beta-endorphin (1 microg) into either the amygdala alone or t

27 Co-administration of beta-endorphin (1 microg) into the amygdala and morphine (1 m

28 rphine (1 microg) into the amygdala and beta-endorphin (1 microg) into the PAG failed to produce inte

29 milar effects of intra-DVC injection of beta-endorphin (1 pmol) are inhibited by naloxone and not by

30 n (epsilon)-opioid-receptor antagonist, beta-endorphin(1-27) prevents these effects of etorphine.

31 one (LAAM), morphine, meperidine, DADL, beta-endorphin(1-31), enkephalins, and dynorphin A(1-17) prod

32 o the suppressive actions of Gly-Gln or beta-endorphin-(1-27) injections that modulate voluntary etha

33 y was shown to be comparable to central beta-endorphin-(1-27) or intraperitoneal (i.p.) naltrexone-in

34 ontrast, the opioid peptidergic agonist beta-endorphin (10 microgram/kg, i.p.) administered after the

35 Following intrathecal administration, beta-endorphin (10-100 nmol) and GRP (1-10 nmol) dose-depende

36 is of fluorogenic peptides based on the beta-endorphin 12-24 sequence, Abz-T-P-L-V-T-L-X(1)-X(2)-N-A-

37 he rostral ventromedial medulla altered beta-endorphin (15 microg) analgesia elicited from the ventro

38 Both morphine (2.5-5 micrograms) and beta-endorphin (2.5-5 micrograms) microinjected into either t

39 Glycyl-L-glutamine (Gly-Gln; beta-endorphin 30-31) is an endogenous dipeptide that is synt

40 investigated whether glycyl-glutamine (beta-endorphin(30-31)), an inhibitory dipeptide synthesized f

41 ffective in reducing morphine (60%) and beta-endorphin (79%) analgesia in the amygdala on the jump te

42 pro-opiomelanocortin, the precursor of beta-endorphin (a known EOP), and constituted the majority of

43 the DVC, whereas the similar effects of beta-endorphin, a peptide derived from the same precursor, ar

44 ted by, in part, the endogenous opioid, beta-endorphin, acting on mu-opioid receptors.

45 y opioids, leading to the proposal that beta-endorphin acts to provide feedback inhibition.

46 piratory depression produced by central beta-endorphin administration.

47 We found that beta-endorphin aggregation and dissociation occur in vitro on

48 arbohydrates exhibit the same effect on beta-endorphin aggregation as phosphate.

49 t as well as more rapid dissociation of beta-endorphin amyloid fibrils at lower pH indicate the contr

50 In contrast, beta-endorphin amyloid fibrils obtained in the presence of he

51 In the beta-endorphin amyloid, every layer of the beta-solenoid is c

52 tors on the assembly and disassembly of beta-endorphin amyloids in vitro.

53 exercise increases blood levels of both beta-endorphin (an opioid) and anandamide (an endocannabinoid

54 wever, the A118G variant receptor binds beta-endorphin, an endogenous opioid that activates the mu op

55 significantly reduce both morphine and beta-endorphin analgesia elicited from the amygdala.

56 for the full expression of morphine and beta-endorphin analgesia elicited from the amygdala.

57 significantly reduced morphine, but not beta-endorphin analgesia in the amygdala on the tail-flick te

58 ultiple modulatory mechanisms mediating beta-endorphin analgesia in the PAG, and in terms of whether

59 The opioid mediation of beta-endorphin analgesia in the ventrolateral periaqueductal

60 Whereas mecamylamine failed to reduce beta-endorphin analgesia on either measure, scopolamine produ

61 %) and transient (30 min) reductions in beta-endorphin analgesia on the jump test, MK-801 produced mi

62 %) and transient (30 min) reductions in beta-endorphin analgesia on the tail-flick test.

63 %) and transient (30 min) reductions in beta-endorphin analgesia on the tail-flick test.

64 es with mice confirm that these glycosylated endorphin analogues are potential drug candidates that p

65 A series of glycosylated endorphin analogues designed to penetrate the blood-brai

66 Glycosylated beta-endorphin analogues of various amphipathicity were studi

67 es in the helical address region of the beta-endorphin analogues without destroying mu-, delta-, or k

68 gy states are suggested for the glycosylated endorphin analogues, a flexible aqueous state and a rest

69 owed colocalization of cathepsin L with beta-endorphin and alpha-MSH in the intermediate pituitary an

70 tion, mediated by the hedonic action of beta-endorphin and anhedonic effects of withdrawal, may theor

71 e neurons produce the endogenous opioid beta-endorphin and are heavily regulated by opioids.

72 As the opioid peptides beta-endorphin and enkephalin increase splenic NK cell functi

73 measurement of instrumental behavior of beta-endorphin and enkephalin knock-out mice that both opioid

74 We conclude that both beta-endorphin and enkephalin positively contribute to the in

75 nules yet expresses endogenous opioids (beta-endorphin and Met-enkephalin) and uroguanylin in apical

76 ors (MOR, OPRM1) mediate the effects of beta-endorphin and modulate many biological functions includi

77 In addition, we have shown that beta-endorphin and mu-opiate receptor are expressed at the pr

78 The expression of both beta-endorphin and mu-opiate receptor correlated positively w

79 try and immunoelectron microscopy using beta-endorphin and mu-opiate receptor specific antibodies.

80 e brain-to-blood transport of morphine, beta-endorphin and other opioids.

81 ) neurons release the endogenous opioid beta-endorphin and POMC neuron activity is inhibited by opioi

82 infiltration of immunocytes containing beta-endorphin and the consequent decrease of the beta-endorp

83 uctural differences between melittin or beta-endorphin and their respective synthetic analogs.

84 ver, neurons triple-labeled with c-Fos, beta-endorphin and VGLUT3 were noted in this region following

85 However, endorphins and dopamine have a much wider compass than o

86 pletely prevented carboxy-shortening of beta-endorphins and greatly diminished conversion of beta-lip

87 n MRM transitions for alpha-endorphin, gamma-endorphin, and [D-Ala(2)]-gamma-endorphin were m/z 873.6

88 euroendocrine peptides (dynorphin A-17, beta-endorphin, and alpha- melanocyte-stimulating hormone) in

89 nes adrenocorticotropic hormone (ACTH), beta-endorphin, and alpha-melanocyte stimulating hormone (alp

90 cathepsin L in the production of ACTH, beta-endorphin, and alpha-MSH peptide hormones in the regulat

91 ut mice showed major decreases in ACTH, beta-endorphin, and alpha-MSH that were reduced to 23, 18, an

92 alpha-, beta-, and gamma-melanotropin, beta-endorphin, and beta-lipotropin.

93 ropin-releasing hormone (GnRH), VP, OT, beta-endorphin, and dopamine neurons, are responsive to mu-re

94 iomelanocortin (POMC), the precursor to beta-endorphin, and endomorphin 1 and 2 on sectioned rat fore

95 ioid receptor agonists (e.g., morphine, beta-endorphin, and enkephalin) inhibit luteinizing hormone (

96 dotropin-releasing hormone-I, dopamine, beta-endorphin, and gonadotropin-releasing hormone-II neurons

97 gesic responses induced by morphine and beta-endorphin, and indicate that the latter response is medi

98 actin, corticotropin-releasing hormone, beta-endorphin, and somatotropin release-inhibiting factor.

99 as well as its derivatives beta LPH and beta-endorphin, and that this process is modulated by TPA, IL

100 lications for theories of the involvement of endorphins, and as a causal factor.

101 ived feeding states but were reduced in beta-endorphin- and enkephalin-deficient mice only when they

102 nmol) dose-dependently attenuates both beta-endorphin- and GRP-elicited robust scratching without af

103 The same pathway produces beta-endorphin, another POMC derivative, which potentially co

104 ted for three different receptors: anti-beta-endorphin anti-body, streptavidin, and thrombin, and the

105 n, growth hormone releasing factor, and beta-endorphin are nearly equivalent substrates for the enzym

106 Enkephalins and beta-endorphin are nonselective endogenous MOR ligands.

107 POMC), and its opioid cleavage product, beta-endorphin, are expressed in the mouse retina.

108 ng a monoclonal antibody (3E-7) against beta-endorphin as a target, we selected a single peptide with

109 ntial affinity to the endogenous ligand beta-endorphin as well as alterations in pain sensitivity, dr

110 Wild type IDE cleaved beta-endorphin at Leu(17)-Phe(18) and Phe(18)-Lys(19), wherea

111 Nardilysin cleaves beta-endorphin at the monobasic site, Phe(17)-Lys(18), with a

112 in pain modulation-metenkephalin (ME), beta-endorphin (BE), and substance P (SP)-in patients undergo

113 Within 36 h after TPA stimulation, beta-endorphin became undetectable in cell extracts, coincidi

114 To enhance beta-endorphin (BEP), the endogenous opioid polypeptide that

115 ic NSCs differentiated these cells into beta-endorphin (BEP)-producing neurons in culture.

116 The endogenous peptides beta-endorphin (beta-END) and neuropeptide Y (NPY) have been

117 leasing hormone (CRH), urocortin (Ucn), beta-endorphin (beta-END), ACTH, and corticosterone (CORT) or

118 also exists for the endogenous opiate, beta-endorphin (beta-END).

119 The enzymatic cleavage products of beta-endorphin (beta-endorphin1-27 and Gly-Gln) reduce volunt

120 The role of beta-endorphin (beta-EP) in ethanol-altered NK cell cytolytic

121 The mechanism by which ethanol induces beta-endorphin (beta-EP) neuronal death during the developmen

122 system is involved in ethanol-regulated beta-endorphin (beta-EP) release from rat hypothalamic neuron

123 beta-endorphin to beta-endorphin 1-17 (gamma-endorphin), beta-endorphin 1-18, and their corresponding

124 ced by the mu-sensitive opioid peptide, beta-endorphin (betaEND, 10 microg, i.c.v.) was significantly

125 CB1R activation selectively increases beta-endorphin but not alpha-melanocyte-stimulating hormone r

126 Thus, beta-endorphin cell therapy may offer some therapeutic value

127 A recognized beta-endorphin cleavage product, Gly-Gln, inhibits voluntary

128 of cell bodies containing enkephalin or beta-endorphin, colchicine (90-100 microg/kg) was injected in

129 G) may have higher receptor binding for beta-endorphin compared with AA homozygotes that may contribu

130 of oxidation products of NO as well as beta-endorphin, compared to levels in fractions collected und

131 in arterial pressure elicited by i.c.v. beta-endorphin, consistent with evidence that cyclic dipeptid

132 The results suggest that although beta-endorphin-containing fibres are absent in many parts of

133 y, CB(2) immunolabeling was detected on beta-endorphin-containing keratinocytes in stratum granulosum

134 phin and the consequent decrease of the beta-endorphin content in the inflamed tissue.

135 peritoneally twice at 3 h intervals, and the endorphin content of microdialysates was analyzed by a s

136 though conversion of beta-lipotropin to beta-endorphin decreased, the lack of PC2 activity caused an

137 Adult male beta-endorphin deficient and wild type mice were subjected to

138 Overall, the beta-endorphin deficient mice and wild type mice had fairly s

139 After the conflict, the beta-endorphin deficient mice had higher corticosterone level

140 e aggressive conspecific several of the beta-endorphin deficient mice showed clear signs of counter a

141 In this experiment beta-endorphin deficient mice were used to study the role of

142 turned to baseline levels faster in the beta-endorphin deficient mice.

143 In this study, we used the beta-endorphin deficient mutant mouse line C57BL/6-Pomc1(tm1L

144 in proenkephalin knockout (PENK KO) and beta-endorphin-deficient (BEND KO) mice, and how the body wei

145 Herein we demonstrate that morphine and beta-endorphin disrupt this long-range synchrony of gamma osc

146 allenge the dogma that shorter forms of beta-endorphin do not exhibit receptor activity; we show that

147 activity and the stimulated release of beta-endorphin during exposure of rats to N(2)O.

148 u and kappa opioid receptors as well as beta-endorphin each produce analgesia elicited from the amygd

149 ies have demonstrated that morphine and beta-endorphin employ different anatomical and neurochemical

150 at's hindpaw elicits an accumulation of beta-endorphin-(END) containing immune cells.

151 d neurons double-labeled with c-Fos and beta-endorphin, enkephalin or VGLUT3 in the ARC were signific

152 er, growth hormone releasing factor and beta-endorphin exhibit a 40-fold higher kcat, but a 10-fold d

153 nic mice with a selective deficiency of beta-endorphin exhibit normal analgesia in response to morphi

154 UVB stimulated beta-endorphin expression was higher in D2 than in B6.

155 beta-endorphin), heterozygous mice (50% beta-endorphin expression) and sibling wildtype mice from the

156 as an acidic pH but, on exocytosis, the beta-endorphin fibril would encounter neutral pH conditions (

157 We find that beta-endorphin fibrils are in a beta-solenoid conformation th

158 We find that beta-endorphin fibrils are in a beta-solenoid conformation wi

159 eptor activation induces the release of beta-endorphin from keratinocytes and the activation of G-pro

160 nt POMC cDNA produced a mutant beta-MSH/beta-endorphin fusion protein.

161 sor-to-product ion MRM transitions for alpha-endorphin, gamma-endorphin, and [D-Ala(2)]-gamma-endorph

162 h the rank order of etorphine > DAMGO = beta-endorphin > morphine > butorphanol, and the affinity of

163 beta-Endorphin had an LOD of 5 nM when detected directly, but

164 Functional studies showed that beta-endorphin has potent melanogenic, mitogenic, and dendrit

165 ting hormone; and the endogenous opioid beta-endorphin) have a diverse array of biological activities

166 ozygous knockout mice (entirely lacking beta-endorphin), heterozygous mice (50% beta-endorphin expres

167 hemorrhage increased Fos expression by beta-endorphin immunoreactive neurons significantly.

168 The proportion of beta-endorphin immunoreactive neurons that expressed Fos immu

169 beta-endorphin immunostaining, whereas beta-endorphin-immunoreactive neurons were absent in retinas

170 xtracts, coinciding with an increase of beta-endorphin-immunoreactive protein in the culture medium.

171 significant increases in POMC mRNA and beta-endorphin immunoreactivity in both ipsilateral and contr

172 ressing amacrine cells was positive for beta-endorphin immunostaining, whereas beta-endorphin-immunor

173 h nerve fibers containing enkephalin or beta-endorphin in both the rVLM and vlPAG.

174 A physiological role for beta-endorphin in endogenous pain inhibition was investigated

175 ed secretion of both chromogranin A and beta-endorphin in response to the usual secretagogue, cortico

176 /or dendrites) containing enkephalin or beta-endorphin in specific regions of the brain stem.

177 nalgesia elicited by either morphine or beta-endorphin in the amygdala could be altered by either the

178 omelanocortin (POMC) neurons to release beta-endorphin in the arcuate nucleus (ARC) of the hypothalam

179 A, orexin B, and a novel isoform of rat beta-endorphin in the arcuate nucleus.

180 hat enhancement of endogenous levels of beta-endorphin in the hypothalamus via beta-endorphin neuron

181 on of AAS also increased the content of beta-endorphin in the midline thalamus, suggesting a possible

182 but decreased the potency of the opioid beta-endorphin in the periaqueductal gray region of the midbr

183 20 cells resulted in increased ACTH and beta-endorphin in the regulated secretory pathway.

184 adiation, to date a functional role for beta-endorphin in the regulation of human epidermal melanocyt

185 lanocyte-stimulating hormone (MSH), and beta-endorphin in the regulation of skin pigmentation, and a

186 he data do not support a major role for beta-endorphin in the regulation of sleep or social stress-in

187 ivates neurons containing enkephalin or beta-endorphin in the rVLM as well as in the periaqueductal g

188 rphin were used to study the release of beta-endorphin in the urethane anaesthetized rat following el

189 nal structures containing enkephalin or beta-endorphin in these regions.

190 ation of epidermal ACTH, alpha-MSH, and beta-endorphin in vitiligo owing to oxidation of methionine r

191 , leu-enkephalin, dynorphin A(1-8), and beta-endorphin in vivo.

192 Quantification of alpha- and gamma-endorphins in rat brain using liquid chromatography-elec

193 ndogenous concentrations of alpha- and gamma-endorphins in rat brains were 13.8+/-0.57 (mean+/-SD; n=

194 eficient mice were used to study the role of endorphins in the acute physiological and behavioral res

195 transiently elevated extracellular levels of endorphins in the nucleus accumbens, whereas nicotine an

196 mission of endogenous opioid peptides (i.e., endorphins) in the nucleus accumbens.

197 Beta endorphin-induced constriction was enhanced following FP

198 produced a dose-dependent inhibition of beta-endorphin-induced hypotension, but not bradycardia, with

199 beta-endorphin inhibition of tumor progression also involves

200 ctive toward the physiological peptides beta-endorphin, insulin, and amyloid beta peptide 1-40.

201 administration of subthreshold doses of beta-endorphin into both structures also results in a profoun

202 doses of morphine into both structures, beta-endorphin into both structures, morphine into one struct

203 to the other structure, or morphine and beta-endorphin into one structure.

204 of morphine, mu-selective agonists and beta-endorphin into the amygdala.

205 ctures, morphine into one structure and beta-endorphin into the other structure, or morphine and beta

206 Beta-endorphin is an endogenous opioid peptide that is releas

207 beta-Endorphin is an opioid peptide cleaved from the precurso

208 Furthermore, beta-endorphin is approximately three times more potent at th

209 The cancer-preventive effect of beta-endorphin is mediated through the suppression of sympath

210 l stimulus was applied, suggesting that beta-endorphin is necessary for CB(2) receptor-mediated antin

211 Whereas plasma beta-endorphin is reported to increase after exposure to ultr

212 important mechanism of the transport of beta-endorphin is the cerebrospinal fluid.

213 [D-Ala(2)]-gamma-endorphin is used as an internal standard.

214 rodents, another POMC-derived peptide, beta-endorphin, is coordinately synthesized in skin, elevatin

215 e and behavioral effects were absent in beta-endorphin knockout mice and in mice lacking p53-mediated

216 An antibody that selectively recognized beta-endorphin labeled fibers and neurons in the ventral horn

217 used an increase in beta-lipotropin and beta-endorphin levels in the mutant animals, but no increases

218 beta-endorphin levels increased in the inflamed paw, and this

219 on, and plasma interleukin-1 (IL-1) and beta-endorphin levels measured.

220 reatening episodes implicates increased beta-endorphin levels resulting from acid-mediated esophageal

221 Resting plasma beta-endorphin levels were significantly higher in the HPT <4

222 en, dyadic satisfaction correlated with beta-endorphin levels, depression, and perception of illness.

223 dic satisfaction scores correlated with beta-endorphin levels.

224 Moreover, we show that oxidized beta-endorphin loses its function in the promotion of pigment

225 ypothesize that this drug-induced release of endorphins may contribute to the positive reinforcing an

226 A popular belief has been that endogenous endorphins mediate these beneficial effects.

227 itary chemosensory cells that coexpress beta-endorphin, Met-enkephalin, uroguanylin, and Trpm5 exist

228 In conclusion, the results suggest that beta-endorphin modulates the acute endocrine, thermoregulator

229 These data support the hypothesis that beta-endorphin modulates the response to EtOH.

230 sal links for itch-eliciting effects by beta-endorphin-MOP receptor and GRP-BB2 receptor systems and

231 roM concentrations of etorphine, DAMGO, beta-endorphin, morphine, and butorphanol, DAMGO-stimulated G

232 igned to examine the involvement of the beta-endorphin/mu-opiate receptor system in human epidermal m

233 cortin-1 receptor, we conclude that the beta-endorphin/mu-opiate receptor system participates in the

234 melanocytes express a fully functioning beta-endorphin/mu-opiate receptor system.

235 beta-endorphin in the hypothalamus via beta-endorphin neuron transplantation suppresses stress respo

236 e ethanol-induced neuronal death of the beta-endorphin neuron.

237 sition of the complement protein C1q in beta-endorphin neuronal cells in both in vitro and in vivo sy

238 lates exosome-mediated, ethanol-induced beta-endorphin neuronal death.SIGNIFICANCE STATEMENT Neurotox

239 treatments increased the number and the beta-endorphin neuronal killing activity of microglial exosom

240 2.6%, depending on neuronal location), beta-endorphin neurons (68.3.0 +/- 4.4%), and VP neurons (41-

241 ction; and ultimately cellular death of beta-endorphin neurons.

242 hyperpolarize guinea pig hypothalamic (beta-endorphin) neurons.

243 to traditional mu and kappa opioids and beta-endorphin, none of the OFQ/N fragments in the amygdala e

244 beta LPH and beta-endorphin of keratinocyte origin may thus be involved in

245 epinephrine and norepinephrine but not beta-endorphin or cortisol.

246 dynorphin1-13 but not antisera against beta-endorphin or methionine-enkephalin.

247 ardiorespiratory depression produced by beta-endorphin or morphine.

248 D can improve the sequence coverage for beta-endorphin over performing ECD alone (i.e., from 72 to 97

249 orks) to show that three neuropeptides (beta-endorphin, oxytocin, and dopamine) play particularly imp

250 Glycopeptides related to beta-endorphin penetrate the blood-brain barrier (BBB) of mic

251 N) (P<0.05), but did not have lower PVN beta-endorphin peptide levels (0.05).

252 piomelanocortin (POMC) neuron-producing beta-endorphin peptides in the hypothalamus in a postnatal ra

253 and synthetic agonists including endogenous endorphin peptides, morphine and methadone.

254 The opioid peptide beta-endorphin plays a critical role in bringing the stress a

255 n inhibitory dipeptide synthesized from beta-endorphin post-translationally, inhibits IL-1beta and PG

256 V8 expressing the analgesic gene prepro-beta-endorphin (ppbetaEP) led to significant (P < 0.0001) rev

257 for insulin-degrading enzyme as both a beta-endorphin-processing and -inactivating enzyme is implica

258 experiments tested the hypothesis that beta-endorphin-producing neurons, that is, proopiomelanocorti

259 c acid (GABA), neuropeptide Y (NPY), or beta-endorphin receptor blockade in the ipsilateral hypothala

260 ascular reflexes through enkephalin- or beta-endorphin-related opioid receptors in the rostral ventro

261 ature, at least in part, by stimulating beta-endorphin release from pro-opiomelanocortin neurons that

262 AM1241 stimulated beta-endorphin release from rat skin tissue and from cultured

263 oid receptors (MORs) and an increase in beta-endorphins released into the VTA and the plasma.

264 The time-integrated beta-endorphin response to CRH was greater in the patients wi

265 Depolarization-mediated beta-endorphin secretion was greatly enhanced in the GAP-43-e

266 , sensation, plasma levels of cortisol, beta-endorphin, selected gut neuropeptides, norepinephrine, e

267 keratinocytes, subsequently increasing beta-endorphin signaling at opioid receptors, and produces an

268 During this period, beta-endorphin stimulates PRL secretion by regulation of dopa

269 (tail-flick: 70-75%; jump: 60-81%) and beta-endorphin (tail-flick: 100%; jump: 93%) analgesia elicit

270 lpha-melanocyte-stimulating hormone and beta-endorphin, the glucocorticoids; and the catecholamines n

271 hormone (alpha-Msh) and carboxy-cleaved beta-endorphin, the products of Cpe-dependent processing of P

272 shown the distribution of dynorphin and beta-endorphin throughout social behavior circuits within the

273 ine contains a peptidase which converts beta-endorphin to beta-endorphin 1-17 (gamma-endorphin), beta

274 attachment, binding of the neuropeptide beta-endorphin to mu-opioid receptors in the central nervous

275 ne regulating feeding behavior, whereas beta-endorphin underlies orosensory reward in high need state

276 geting mu-receptors, such as enkephalins and endorphins, underlying the regulation of feeding and bod

277 Analyses of beta-endorphin variants carrying mutations in Glu8 support th

278 A functional role for beta-endorphin was assessed in epidermal melanocyte cultures

279 125I-beta-Endorphin was cross-linked to preparations enriched in p

280 Little immunoreactive-beta-endorphin was detected in the areas of brain sampled dur

281 the amyloid fibril of the human hormone beta-endorphin was determined by solid-state NMR.

282 Basal secretion of beta-endorphin was first observed at Embryonic Day 13.5 (e13.

283 d in rats when naloxone or antiserum to beta-endorphin was injected in the hindpaw where the noxious

284 Hindpaw injection of beta-endorphin was sufficient to produce antinociception.

285 mity to fibers containing enkephalin or beta-endorphin, was observed in the rVLM and ventrolateral PA

286 ate an NO-dependent neuronal release of beta-endorphin, we conducted a ventricular-cisternal perfusio

287 en the powerful analgesic properties of beta-endorphin, we tested this hypothesis using pain toleranc

288 tern blot analysis, POMC, beta LPH, and beta-endorphin were detected in cell extracts under baseline

289 PAG, while no cell bodies labeled with beta-endorphin were identified in either region.

290 rphin, gamma-endorphin, and [D-Ala(2)]-gamma-endorphin were m/z 873.6-->429.6; 929.6-->542.3; 936.6--

291 Met-Enkephalin and beta-Endorphin were not affected by dietary treatment.

292 d antibodies to the carboxy-terminus of beta-endorphin were used to study the release of beta-endorph

293 chanism allows for the local release of beta-endorphin, where CB(2) receptors are present, leading to

294 y to inflamed sites, where they release beta-endorphin which activates peripheral opioid receptors to

295 timulates release from keratinocytes of beta-endorphin, which acts at local neuronal mu-opioid recept

296 and exercise both induce the release of beta-endorphin, which plays an important role in the modulati

297 Unlike beta-endorphin, which produces itch and attenuates inflammato

298 keratinocytes of the endogenous opioid beta-endorphin, which then acts at opioid receptors on primar

299 There was no correlation of IL-1 or beta-endorphin with any psychosocial or behavioral compliance

300 copy studies revealed an association of beta-endorphin with melanosomes.