ライフサイエンスコーパス: endospore

1 nter) and Clostridia (forming heat-resistant endospores).

2 nthracis persists as a metabolically dormant endospore.

3 nvironment, B. anthracis exists as a dormant endospore.

4 composed of two layers, the exospore and the endospore.

5 e wall protein (SWP3) that is located in the endospore.

6 le as a metabolically dormant cell type, the endospore.

7 inate complexes surrounding each germinating endospore.

8 problem of real-time detection of bacterial endospores.

9 samples that contained only several hundred endospores.

10 gs containing multiple cysts (sporangia) and endospores.

11 pring of Epulopiscium-like bacteria are true endospores.

12 sibility that the phase-bright offspring are endospores.

13 rotein was immunolocalized to the surface of endospores.

14 ical of the parental strain and did not form endospores.

15 y to produce progeny in the form of multiple endospores.

16 produce live offspring instead of quiescent endospores.

17 ress conditions by transforming into dormant endospores.

18 tat on Earth and features abundant bacterial endospores.

19 pherule is filled with multiple cells called endospores.

20 the spore photoproduct (SP), in germinating endospores.

21 responsible for the strong UV resistance of endospores.

22 n the genomic DNA of UV-irradiated bacterial endospores.

23 clusive DNA photodamage product in bacterial endospores.

24 that are capable of producing heat-resistant endospores.

25 clusive DNA photodamage product in bacterial endospores.

26 to accumulate in the surface regions of the endospores.

27 ents of the protective surface layers of the endospores.

28 on and enumeration of individual germinating endospores.

29 ogether, the two pathways allow B. anthracis endospores a broader recognition of purines and amino ac

30 ted of juxtaposed immature spherules without endospores, a germinating endospore, or thick-walled hyp

31 ThT and (ii) the accumulation of ThT in the endospores, affording fluorescence images with excellent

32 oluble components of the cell, including the endospore and cytoplasm, and in ligand blots binds to pu

33 morphological similarity between developing endospores and Epulopiscium offspring, we hypothesized t

34 ped for detection of Bacillus anthracis (BA) endospores and for differentiation of them from other sp

35 mer, spore photoproduct (SP), in germinating endospores and is responsible for the strong UV resistan

36 neered probiotics limited the germination of endospores and the growth of vegetative cells of C. diff

37 lostridia classes, are their ability to form endospores and their "Gram-positive" single-membraned, t

38 database of Raman spectra of single Bacillus endospores and to calculate classification functions, wh

39 Longer-term thermal tolerance of endospores, and how long they could persist in an enviro

40 type of pili, referred to here as Fibrillar ENdospore Appendages or F-ENA.

41 ation of a small sample of Bacillus subtilis endospores (approximately 10(4) spores).

42 In addition, endospores are formed as part of the normal daily life c

43 We show that multiple endospores are generated both by asymmetric division at

44 These endospores are likely expelled from warm subsurface envi

45 Bacterial endospores are some of the most resilient forms of life

46 Thermophilic endospores are widespread in cold marine sediments where

47 ture and structural variability of bacterial endospores as a function of spatial and developmental or

48 sms was investigated using Bacillus subtilis endospores as model microbial agents and simulated and n

49 All members of the Bacillus genus produce endospores as part of their life cycle; however, it is n

50 s) or quality (i.e., UV resistance of viable endospores) aspects could readily shift populations betw

51 of the cell and by symmetric division of the endospores at an early stage of their development.

52 ative cells drop two orders of magnitude and endospores become more than 6000 times more abundant tha

53 (OFF) state produced a lower yield of viable endospores but endowed them with vastly increased UV res

54 the Veillonellaceae) of Clostridia that form endospores but that are surprisingly "Gram negative," po

55 We also failed to detect the presence of endospores by light microscopy or by testing for heat-re

56 Bacterial endospores can remain dormant for decades yet can respon

57 To test whether thermophilic endospores can survive prolonged exposure to high temper

58 dospores is surrounded by the densely packed endospore coat and exosporium, containing amyloid or amy

59 t, it is the impenetrable composition of the endospore coat and the exosporium that makes staining me

60 acid (DPA) is a major component of bacterial endospores, comprising 5-15% of the spore dry weight, an

61 The bacterial endospore cortex peptidoglycan is synthesized between th

62 to be a quantity versus quality trade-off in endospore crops.

63 Bacterial endospores derive much of their longevity and resistance

64 UV resistance of bacterial endospores derives from a unique DNA photochemistry in w

65 porium that makes staining methodologies for endospore detection complex and challenging.

66 ect the forespore and the mother cell during endospore development in the bacterium Bacillus subtilis

67 At an early stage during Bacillus subtilis endospore development the bacterium divides asymmetrical

68 Asymmetric division, a hallmark of endospore development, generates two cells, a larger mot

69 A metalloproteinase (Mep1) secreted during endospore differentiation digests an immunodominant cell

70 Bacterial endospore dormancy and resistance properties depend on t

71 ination, implicating gerS in the breaking of endospore dormancy in vivo.

72 isoprenoid metabolism in the mother cell and endospore during sporulation in B. subtilis.

73 gen (SOWgp) and prevents host recognition of endospores during the phase of development when these fu

74 Mature spherules rupture and release endospores, each of which can form another spherule, in

75 including 20 transcripts whose expression is endospore-enriched and 14 putative secreted effectors wh

76 we also found that B. anthracis bacilli and endospores exhibited arginase activity, possibly competi

77 olyspora relies on the formation of multiple endospores for reproduction.

78 al to all clostridia is the orchestration of endospore formation (i.e., sporulation) and, specificall

79 Bacterial endospore formation (i.e., sporulation) is a well-studie

80 Endospore formation (sporulation) is a well conserved mi

81 Endospore formation (sporulation), extensively studied i

82 The broad distribution of endospore formation among the Epulopiscium phylogenetic

83 hich are expressed in the mother cell during endospore formation and which are essential for the acti

84 asis via a high-cost outer cell membrane and endospore formation as a response to nutrient deprivatio

85 At an early stage in endospore formation Bacillus subtilis partitions itself

86 Studies of endospore formation by Bacillus subtilis and fruiting bo

87 Endospore formation by Bacillus subtilis involves three

88 Endospore formation by Bacillus subtilis is a complex an

89 up III IMMP that regulates Bacillus subtilis endospore formation by cleaving Pro-sigma(K) and releasi

90 Endospore formation in amino-acid-rich medium was signif

91 l that B. subtilis is an excellent model for endospore formation in B. anthracis, while underscoring

92 During endospore formation in Bacillus subtilis an asymmetric d

93 n and DNA packaging, that are common to both endospore formation in Bacillus subtilis and the product

94 Endospore formation in Bacillus subtilis begins with an

95 Endospore formation in Bacillus subtilis is primarily de

96 Endospore formation in Bacillus subtilis provides an ide

97 Recent studies on endospore formation in Bacillus subtilis suggest that an

98 At the onset of endospore formation in Bacillus subtilis the DNA-binding

99 During endospore formation in Bacillus subtilis, over two dozen

100 During endospore formation in Bacillus subtilis, over two dozen

101 During endospore formation in Bacillus subtilis, several integr

102 At the onset of endospore formation in Bacillus subtilis, the DNA bindin

103 During endospore formation in Bacillus subtilis, the DNA bindin

104 nscription factor controls the initiation of endospore formation in Clostridium acetobutylicum, but g

105 (iii) The molecular apparatus of endospore formation in Clostridium serves as raw materia

106 The bacterium Bacillus subtilis undergoes endospore formation in response to starvation.

107 ot all, highly conserved genes diagnostic of endospore formation in the genomes of low G+C Gram-posit

108 The molecular basis of endospore formation in the model gram-positive bacterium

109 Endospore formation is coordinated with transit of the b

110 A key step in bacterial endospore formation is engulfment, during which one bact

111 A hallmark of bacterial endospore formation is engulfment, during which the memb

112 eed to conserve biosynthetic capacity during endospore formation might have favored the evolution of

113 (chemotaxis, competence for DNA uptake, and endospore formation) by analyzing their phylogenetic dis

114 During Bacillus subtilis endospore formation, a complex protein coat is assembled

115 ases SpoIIE, which controls cell-fate during endospore formation, and RsbU, which initiates the gener

116 teria to reduced and stringent selection for endospore formation, as well as to novel environmental c

117 licum, in contrast to the model organism for endospore formation, Bacillus subtilis, and confirm that

118 How solvent production is coupled to endospore formation--both stationary-phase events--remai

119 ween the appearance of clostridial forms and endospore formation.

120 ring production in Epulopiscium evolved from endospore formation.

121 f several genes required during the onset of endospore formation.

122 ression of CTS1 is markedly increased during endospore formation.

123 f spoIIG and other promoters at the onset of endospore formation.

124 complex developmental program culminating in endospore formation.

125 on efficiency and a delay in the kinetics of endospore formation.

126 thin a cell" structure that is a hallmark of endospore formation.

127 membrane fission for both cell division and endospore formation.

128 o0J is involved in cell cycle changes during endospore formation.

129 leaves Pro-sigma(K) during Bacillus subtilis endospore formation.

130 duction in Epulopiscium shares features with endospore formation.

131 is unlikely that Mycobacterium is capable of endospore formation.

132 Endospores formed by Bacillus subtilis are encased in a

133 e intensively studied, genetically tractable endospore-former, Bacillus subtilis, is an ideal subject

134 MdfA is conserved in aerobic endospore formers and required for spore resistance to h

135 Unlike most endospore formers, Epulopiscium partitions only a small

136 entogenic clostridia are strictly anaerobic, endospore forming bacteria that produce a large array of

137 The endospore forming bacterium Bacillus anthracis causes le

138 0A that is highly conserved among species of endospore-forming Bacillus and Clostridium and which enc

139 of cellular propagation that originates with endospore-forming Bacillus and Clostridium spp., which r

140 Fifteen endospore-forming Bacillus species were confirmed in a s

141 of information rich Raman fingerprints from endospore-forming bacteria belonging to the genera Bacil

142 Thirty-six strains of aerobic endospore-forming bacteria confirmed by polyphasic taxon

143 In response to starvation, endospore-forming bacteria differentiate into stress-res

144 Many endospore-forming bacteria embed alanine racemases into

145 The endospore-forming bacteria have persisted on earth perha

146 lis were present in all of the Gram-positive endospore-forming bacteria whose genome has been sequenc

147 SpoIIID is evolutionarily conserved in endospore-forming bacteria, and it activates or represse

148 etic position, among low G + C Gram-positive endospore-forming bacteria, and the remarkable morpholog

149 sK/SpoIIIE paralogues is not conserved among endospore-forming bacteria, but is highly conserved with

150 Thirty-six strains of aerobic endospore-forming bacteria, consisting of six Bacillus s

151 ine proteases that is highly conserved among endospore-forming bacteria, contributes to SASP degradat

152 D265 and Y264 are conserved among endospore-forming bacteria, raising the possibility that

153 Unlike most endospore-forming bacteria, sporulation is an obligate p

154 Using gene conservation among endospore-forming bacteria, we identified eight previous

155 Since SpoIIID is conserved only in endospore-forming bacteria, which include important path

156 m polyspora and Clostridium lentocellum, are endospore-forming bacteria, which raises the possibility

157 at separates forespores from mother cells in endospore-forming bacteria.

158 pressed during sporulation as it is in other endospore-forming bacteria.

159 fspring was the ancestor of all contemporary endospore-forming bacteria.

160 s the master regulator of sporulation in all endospore-forming bacteria.

161 ution of the sporulation network in multiple endospore-forming bacteria.

162 omologous protein from the distantly related endospore-forming bacterium Clostridium acetobutylicum,

163 om the genome of the closely related but not endospore-forming bacterium Listeria monocytogenes, ther

164 Bacillus anthracis is an endospore-forming bacterium that causes inhalational ant

165 reduction, coinciding with an enrichment of endospore-forming Clostridia.

166 Pasteuria penetrans is a gram-positive, endospore-forming eubacterium that apparently is a membe

167 viously sent to the FDOH laboratory, 56 were endospore-forming gram-positive rods and only 7 grew on

168 nt Metabacterium polyspora is an uncultured, endospore-forming member of the Firmicutes.

169 yticum lentocellum DSM 5427 is an anaerobic, endospore-forming member of the Firmicutes.

170 Sporulation in the model endospore-forming organism Bacillus subtilis proceeds vi

171 Bacillus subtilis, a Gram-positive, endospore-forming soil bacterium, was grown in media mad

172 Certain endospore-forming soil dwelling bacteria are important h

173 (G) regulons that are widely conserved among endospore-forming species but are absent from closely re

174 is regulated differently from that of other endospore-forming species.

175 ncharacterized genes that are enriched among endospore-forming species.

176 In an oil reservoir context, heat-resistant endospore-forming sulfate-reducing bacteria have a survi

177 confirmed the close relationship between the endospore-forming surgeonfish symbionts characterized he

178 The ability of the endospore-forming, gram-positive bacterium Bacillus anth

179 tridium sp. strain BNL1100, a Gram-positive, endospore-forming, lignocellulolytic bacterium isolated

180 y fatal disease caused by the gram-positive, endospore-forming, rod-shaped bacterium Bacillus anthrac

181 lysis of Metabacterium polyspora, a multiple-endospore-forming, uncultivated inhabitant of guinea pig

182 Using endospores from both the parental strain B. anthracis St

183 aluate the swab/rinse recovery efficiency of endospores from stainless steel surfaces.

184 Endospore genomes highlight adaptations to life in anoxi

185 A fast Endospore Germinability Assay (EGA) was validated with t

186 Dosage-dependent decrease of surface endospore germinability were observed in dry heat, UV ir

187 oximately 23-34 A would allow passage of the endospore germinants, alanine or inosine but not degrada

188 Upon inoculation into the host the endospores germinate and outgrow into vegetative bacilli

189 in the infectious process Bacillus anthracis endospores germinate and outgrow into vegetative bacilli

190 traditional plate counts to enumerate single endospore germination events for monitoring surface ster

191 minant sensors, was shown to be required for endospore germination in the presence of macrophages and

192 A current model of B. anthracis endospore germination is presented.

193 in Bacillus anthracis that is important for endospore germination triggered by two distinct germinat

194 to monitor the kinetics of Bacillus subtilis endospore germination.

195 erical structures in infected hosts, produce endospores, have not been cultured, and possess mitochon

196 ed upon macrophage infection by B. anthracis endospores; however, ONOO(-) does not appear to exhibit

197 On the basis of putative nuclei and endospores, Huldtgren et al. propose that embryo-like Do

198 The conversion of a growing cell into an endospore in Bacillus subtilis involves a phagocytic-lik

199 the cell surface during sporogony and in the endospore in mature spores.

200 Thermophilic endospores in the permanently cold seabed correlated wit

201 as presented that the spores were similar to endospores in ultrastructure, in heat resistance and in

202 ghly conserved only among bacteria that form endospores, including several important human pathogens.

203 gh-resolution native structures of bacterial endospores, including the exosporium and spore coats of

204 technique is capable of identifying anthrax endospores inside a sealed paper envelope.

205 tylase has been localized to the plasmalemma-endospore interface.

206 The endospore is known to contain chitin, and a putative gly

207 A major structural element of bacterial endospores is a peptidoglycan (PG) wall.

208 photolesion found in UV-irradiated bacterial endospores is a thymine dimer, 5-thyminyl-5,6-dihydrothy

209 The UV resistance of bacterial endospores is an important quality supporting their surv

210 The outer membrane of endospores is surrounded by the densely packed endospore

211 The capacity to form endospores is unique to certain members of the low-G+C g

212 o its spherical shape, containing hundred of endospores, it was thought to be closely related to the

213 We engineer endospore limited B. subtilis cells to become a structur

214 The Bacillus anthracis endospore loses resistance properties during germination

215 ivation mutant stalled in sporulation during endospore maturation, exhibiting engulfment and partial

216 formation of a highly desiccation-resistant endospore might serve as a logical osmostress escape rou

217 illus anthracis includes both vegetative and endospore morphologies which alternate based on nutrient

218 phenotypes (aerobic, anaerobic, facultative, endospore, motility and Gram negative) from 11,969 uniqu

219 Upon infection, germination of endospores occurs during their internalization within th

220 , which were trained to discriminate between endospores of 66 strains from 13 Bacillus and Bacillus-r

221 pathway in microbial killing, the ability of endospores of B. anthracis to regulate production of thi

222 The endospores of Bacillus anthracis are the infectious part

223 ds are required for efficient germination of endospores of Bacillus anthracis DeltaSterne, a plasmidl

224 The peptidoglycan cortex of endospores of Bacillus species is required for maintenan

225 his study, field tests were carried out with endospores of Bacillus subtilis and coliphage phiX174 ov

226 Endospores of Bacillus subtilis are encased in a thick,

227 Endospores of Bacillus subtilis are enclosed in a protei

228 istic mass spectra from individual bacterial endospores of Bacillus subtilis var. niger were obtained

229 x, an often fatal infection, is initiated by endospores of the bacterium Bacillus anthracis, which ar

230 Germination and outgrowth of endospores of the Gram-positive bacterium Bacillus subti

231 d that retention of SOWgp on the surfaces of endospores of the mutant strain in the presence of high

232 imit for B. anthracis was found to be 50,000 endospores, on the basis of the GC/MS detection limits f

233 ed on either quantity (i.e., yield of viable endospores) or quality (i.e., UV resistance of viable en

234 spherules without endospores, a germinating endospore, or thick-walled hyphal cells.

235 itiated by transcriptional activation during endospore outgrowth.

236 steel coupons inoculated with range of 1,000 endospores per coupon down to sterility.

237 ls in a given population produced one or two endospores per mother cell.

238 most likely xylophagic amitochondriates), an endospore (probably of the filamentous intestinal bacter

239 ntingency locus in the adaptive evolution of endospore properties and (2) bet-hedging between what ap

240 Upon entry into a host, endospores rapidly differentiate into vegetative bacilli

241 A and HPC results were highly correlated for endospore recovery from stainless steel coupons inoculat

242 t out of the subsurface, viable thermophilic endospores reenter the geosphere by sediment burial, ena

243 Germinating endospores release calcium dipicolinate to form highly l

244 e that efficient germination of B. anthracis endospores requires multipartite signals and that gerS-e

245 ybridizing RNA from the developing spherules-endospores (SEs) and hyphae correlated with the appearan

246 the Bacillus cereus pdaA gene (encoding the endospore-specific peptidoglycan-N-acetylmuramic acid de

247 many forms, including formation of Bacillus endospores, Streptomyces exospores, and metabolically la

248 Bacterial spores (endospores), such as those of the pathogens Clostridium

249 ipicolinate (a marker molecule for bacterial endospores, such as Bacillus subtilis and Bacillus anthr

250 A short incubation of bacillus endospore suspensions with ThT, under ambient conditions

251 usually found on the skin, was able to form endospores that endure extreme dryness or nutrient limit

252 iota that are capable of producing resistant endospores that maintain viability within the environmen

253 cillus anthracis forms metabolically dormant endospores that upon germination can cause lethal anthra

254 from two cells that lie side by side to the endospore, the unique cell within a cell structure that

255 between active vegetative cells and dormant endospores through the processes of germination and spor

256 s a 15-minute or faster assay for germinable endospores to complement the conventional lengthy, cultu

257 etely eliminated the ability of B. anthracis endospores to respond to amino-acid and inosine-dependen

258 The endospores, together with the urease and additional mate

259 Antivirulence agents targeting endospore-transmitted Clostridioides difficile infection

260 a rapid analysis system in term of Bacillus endospore typing.

261 e of Komagataeibacter rhaeticus and Bacillus endospores under engineered medium conditions.

262 macrophages (RAW264.7 cells) to B. anthracis endospores up-regulated the expression of NOS 2 12 h aft

263 The endospore upper temperature limit for survival is 140 de

264 f primary murine macrophages to B. anthracis endospores upregulated NOS 2 concomitant with an .NO-dep

265 nthracis Sterne and plasmidless Delta-Sterne endospores was dramatically enhanced in RAW264.7 macroph

266 while germination of nonpathogenic Bacillus endospores was not.

267 acrophage cultures of B. anthracis gerH-null endospores was restored by complementation in trans with

268 Mass spectra of individual Bacillus endospores were measured with a bipolar aerosol time-of-

269 In the populations studied, mature endospores were seen only at night and the majority of c

270 e-Guerin produce a type of spore known as an endospore, which had been observed only in the low G+C g

271 ler cell (forespore) differentiates into the endospore, while the larger cell (mother cell) becomes a

272 e its reproductive potential and supply each endospore with at least one complete copy of the genome.

273 ide an effective and rapid means of staining endospores without the inconvenience of pre- or posttrea