ライフサイエンスコーパス: engage

1 s opposed to a group of viewers-perceives as engaging.

2 At week 72, 1832 (56%) of 3274 were engaged, 1070 (33%) received a refill, and 900 (27%) sel

3 nstrating that aspirations can be altered by engaging 16-18-year-old A level biologists in sustained

4 Using cross-sectional survey data (Engage, 2017-2018) from 1,137 men who have sex with men,

5 vity and regulation in developmental samples engage a robust group of regions that are implicated in

6 The third TCR engaged a flipped peptide conformation, leading to the r

7 he first time, that only the I-PI transition engages a brainstem-wide network, and that rLFPs during

8 expiration during the post-inspiratory phase engages a distributed neuronal population within ventral

9 is asymmetry directs McrC binding so that it engages a single active site, where it then uses an argi

10 in an N-terminal helical peptide region that engages a substrate docking exosite and a C-terminal tra

11 The Fc domain engages a wide spectrum of receptors on discrete cells o

12 phosphorylation at higher concentrations by engaging a feedback mechanism.

13 ions in BMP signaling in two ways: it either engages ACVR1B to activate Smad2/3 signaling or binds AC

14 Background The ENGAGE AF-TIMI 48 trial (Effective Anticoagulation With

15 This strategy conveniently engages alkyl and aryl halides in a wide range of redox

16 Engaging all providers involved in postoperative care is

17 ycin-induced lung fibrosis model, GSK3008348 engages alphavbeta6, induces prolonged inhibition of TGF

18 We recognize the need to engage and educate the next generation of epidemiologist

19 y team, which intensivists are positioned to engage and lead.

20 modes of chromatin remodelers that directly engage and remodel nucleosomes or transcription elongati

21 Strategies to recruit, engage and retain hard-to-reach populations are discusse

22 ate Express employs a sampling probe head to engage and seal against the swipe surface.

23 by treatment of TLR2 (Toll-like receptor 2)-engaged and TLR7 (Toll-like receptor 7)/TLR8 (Toll-like

24 thymus when their new T cell receptor (TCR) engages and signals in response to self-peptides.

25 s, especially using treatments that are more engaging and are associated with better compliance.

26 r ABCG2 a single amino acid is essential for engaging and initiating transport of multiple drugs and

27 unities should have a voice, be informed and engaged, and participate in this transition phase.

28 deacetylase activity of HDAC3 is selectively engaged at ATF3-bound sites that suppress Toll-like rece

29 tories were more cognitively and emotionally engaging at a physiological level when presented in an a

30 hesized that a longer PLP antigen may better engage B cells and designed a peptide encompassing the e

31 ubiquitin through a split recognition motif engaging both the major and the secondary recognition pa

32 e encounter complex before forming the fully engaged bound complex.

33 CD45 is more strongly excluded from bilayer-engaged BRCs than a transmembrane peptide, indicating th

34 h that GW296115 is cell active, and directly engages BRSK2.

35 LHb, were spatially defined, differentially engaged by aversive stimuli, and had distinct electrophy

36 e results indicate that EGCs are selectively engaged by chemosensory blends, suggesting different rol

37 onical resting-state networks preferentially engaged by EL_INSTs were the Limbic and the Frontopariet

38 ely-suggesting them as networks consistently engaged by epileptogenic mass lesions.

39 Moreover, the caspase-autophagy pathway is engaged by fear conditioning to facilitate associative f

40 owever, the brain-wide functional substrates engaged by muscarinic agonists remain poorly understood.

41 ed here, are potent binders of the E-box DNA engaged by Myc for transcriptional activation and that t

42 f the receptors on microglial cells that are engaged by reovirus.

43 elimbic prefrontal cortex (plPFC) circuit is engaged by stress and activation of this pathway in anxi

44 e bacterial and fungal pathogens, mechanisms engaged by viruses have remained elusive.

45 In contrast to VTA, SNc DaNs engage calcium channels to generate action potentials, w

46 ptogenetics or sensory stimulation appear to engage canonical neurocircuits that encompass excitatory

47 ese +TIPs perform various functions, such as engaging cargos for transport or engaging peripheral act

48 like receptor 7)/TLR8 (Toll-like receptor 8)-engaged CD14(+) monocytes with ONX 0914, diminished proi

49 Before engaging CD4, Env adopts an antibody-resistant "closed"

50 -permeable peptides offer the possibility of engaging challenging intracellular targets.

51 ls both in vivo and in vitro These afferents engage cholinergic interneurons, which drive dopamine re

52 modeling complexes, and histone modifiers to engage chromatin, thereby initiating the formation of an

53 owed by an intermediate complex and then, an engaged complex that is competent for substrate unfoldin

54 hancing or dampening inputs, coreceptors can engage concomitant stimulatory and inhibitory signaling

55 s designed that utilizes chemotypes known to engage conserved catalytic protease residues.

56 The sensing of pathogens by macrophages engages conserved signalling pathways and transcription

57 of information for evolutionary biology and engaged considerable public interest.

58 within a complex hypothalamic circuitry that engages distinct hindbrain regions and is innervated by

59 Bone-marrow-derived progenitors actively engage DNA repair but also imprint a formaldehyde-driven

60 ively, these findings illustrate that stress engages dopamine signaling in the VLS to facilitate appe

61 tiple cellular networks may be independently engaged during behavior.

62 temporal lobe (MTL), structures known to be engaged during face and scene identification.

63 It remains unknown which brain networks are engaged during the utterance of fillers.

64 shed light on the mammalian immune pathways engaged during tick-transmitted B. burgdorferi infection

65 IB-binding pocket and the pockets that would engage eIF2alpha during active nucleotide exchange, ther

66 jects such as brands can trigger cognitively engaging, emotional, and socially meaningful experiences

67 HFpEF-specific downregulated genes engaged endoplasmic reticulum stress, autophagy, and ang

68 nced technologies to better target ILC2s and engaging experimental models that better manifest both a

69 induce skin inflammation and anaphylaxis by engaging FcgammaRs, and demonstrate that Fc-engineered v

70 ng ICs with an Fc engineered to be unable to engage FcRn did not.

71 FR was prospectively measured twice (with GC engaged [FFR(eng)] and disengaged [FFR(dis)]) in 202 int

72 Flagellotropic bacteriophages engage flagella to reach the bacterial surface as an eff

73 oupling interface, suggesting a mechanism of engaging G-proteins that may have a distinct dependence

74 11118, and JNJ-61432059) as the major module engaging gamma8 by an H-bond to Asn-172 (gamma8).

75 nd N3 domains in the receptor to transiently engage Hb to remove its heme.

76 E-S and E-K compartments, between ATP-bound engaged heads and the SMC hinge and associated kleisin,

77 mpartment created by Scc2's association with engaged heads whose coiled coils are folded around their

78 ycine lipid classes were previously shown to engage human and mouse Toll-like receptor 2 (TLR2) and t

79 rough its soluble form (sDPP4) that directly engages immune cells.

80 , USA, have congressional experience and who engage in a broader range of activities are more likely

81 Tumors harbor diverse cell types that engage in a dynamic interplay to sustain cancer-specific

82 e embedded in complex communities where they engage in a wide array of intra- and inter-specific inte

83 irst-hand experience in a dynamic fashion to engage in adaptive persistence.

84 This argues that cells engage in aerobic glycolysis when the demand for NAD(+)

85 ros, Helios, Aiolos, Eos, and Pegasus, which engage in both homo- and heterotypic intrafamilial inter

86 hilic N-aryl nitrenoid intermediate that can engage in C-NAr bond formation to construct functionaliz

87 ing from skin wetness enhances the desire to engage in cool-seeking behaviour during passive heat str

88 Furthermore, mitochondria can engage in crosstalk with the tumor microenvironment, and

89 We reconstruct the sequence in which regions engage in decision processing on single trials, thereby

90 or synthetically prepared in pure form, can engage in direct interactions with RNA resulting in mutu

91 only stabilize domain interactions, but also engage in domain dissociation to allosterically invoke a

92 h multiple divergent trityl groups poised to engage in embraces.

93 ccess in Experiment 1 predicted decisions to engage in Experiment 2 and vice-versa.

94 viruses that thrive within these communities engage in extensive cell-cell interactions, which are bo

95 , and that shaken drones were more likely to engage in feeding and grooming than a sham control.

96 idence that lower testosterone men may often engage in greater prosocial behavior compared to higher

97 extracellular domain of LRRTM4 was found to engage in heparan-sulfate dependent binding with pikachu

98 s harbor mobile AR genes and which organisms engage in HGT.

99 their peers hold pro-diversity attitudes and engage in inclusive behaviours.

100 r substrate versatility and their ability to engage in intimate collaborations with translocases and

101 we show that primary mouse and human T cells engage in macropinocytosis that increases in magnitude u

102 The sulfoxides engage in metal-free C-H trifluoromethylthiolation with

103 at prey with more predator experience should engage in more antipredator behaviour, which leads to a

104 ishing that Fe(II) polypyridyl complexes can engage in photoinduced redox reactions but by a mechanis

105 d MLOs is regulated by a domain predicted to engage in protein binding.

106 ut rates are relatively low, but few fellows engage in self-care.

107 e pitted against each other when adolescents engage in social decision making such as giving or shari

108 We consider the ways humans engage in social epistemic actions, to guide each other'

109 These results indicate that lipids engage in specific, trimer-stabilizing interactions that

110 bit notable constraints on the proclivity to engage in such food transfer (particularly chimpanzees),

111 an increased probability of primed cells to engage in target gene expression, correlating with the s

112 treatment, the dlPFC appeared better able to engage in top-down control of the amygdala.

113 s study investigated how experts' ability to engage in velocity-based synchrony affects observers' pe

114 The resulting aryl radicals are engaged in (hetero)biaryl cross-coupling, borylation, an

115 By 2015, APAC was engaged in 50-71% of the virtual flows of water, energy,

116 12 triads (n = 36 participants), while they engaged in a collaborative drawing task based on the soc

117 Infants who engaged in a larger number of CTs in daily life had lowe

118 f stress buffering correlates with more time engaged in allogrooming from naive partners.

119 primary auditory cortex (A1) while mice were engaged in an active listening task.

120 was significantly lower in persons with HIV engaged in an anal cytology screening program.

121 ion in T1D of several essential neural nodes engaged in both cognitive and motor processing.

122 PLWH who were engaged in care (n = 4597) and had QHPs had a higher VS

123 comes, persons with HIV must be consistently engaged in care and able to access uninterrupted treatme

124 across the association and visual cortex are engaged in cognitive processing, including lexical retri

125 to the CNS during CD4+ T cell-initiated EAE engaged in determinant spreading and influenced disease.

126 ross venular walls, thus causing neutrophils engaged in diapedesis to reenter the systemic circulatio

127 Blood vessels are lined by endothelial cells engaged in distinct organ-specific functions but little

128 taldehydes are fluorinated and then directly engaged in enantioselective aldol reactions in a one-pot

129 Forage fish, in contrast, have been engaged in evolutionary arms races with their predators

130 t intrinsic communication of frontal regions engaged in executive functions and emotion regulation re

131 We find that FACT is engaged in extensive interactions with nucleosomal DNA a

132 we show that Myc-driven transcription is re-engaged in mature cardiomyocytes by elevating levels of

133 drinking in persons with alcohol dependence engaged in motivational enhancement therapy.

134 s to the cortical activity of human subjects engaged in music listening, we measured the dynamics of

135 ive illicit opioid use at intake, 14 (46.4%) engaged in opioid use disorder (OUD) treatment during th

136 Neurophysiological studies in monkeys engaged in passive fixation and behavioral tasks suggest

137 ment of many organs and is further crucially engaged in pathophysiological processes underlying cance

138 eliminated, it is essential that scientists engaged in pre-clinical research use "Completely randomi

139 The substrate for ribosomes actively engaged in protein synthesis is a ternary complex of elo

140 communication of the striato-amygdala system engaged in reinforcement-based and emotional learning pr

141 al structure of the bacterial RNA polymerase engaged in reiterative transcription from the pyrG promo

142 dimensions was observed in women from those engaged in skill, power, to mixed and endurance discipli

143 ELKS family Bruchpilot (BRP)-based scaffold engaged in SV recruitment.

144 were active during spatial exploration were engaged in SWR-coupled spindles after behavior.

145 (RyR1), a calcium-activated calcium channel engaged in the binding of ligands.

146 lti-enhancer genes and multi-genic enhancers engaged in the control of divergent molecular pathways.

147 Patients who had engaged in the kidney transplant process received more i

148 surements of RNA polymerase (RNAP) molecules engaged in the process of transcribing a gene of interes

149 has decided to initiate a trial, it remains engaged in the task until the end of the trial.

150 all men who have sex with men (MSM) who have engaged in unprotected sex.

151 othesis that this extinct semiaquatic beaver engaged in woodcutting behaviour for feeding purposes.

152 parameters, most prominently when the mouse engages in a self-paced operand task.

153 be collectively retained by a community that engages in costly HGT.

154 lized 2-azaallyl anion-type nucleophile that engages in dearomative C-C bond-forming reactions with a

155 proton in the trifluoroacetamide derivative engages in extended H-bond interactions in its crystal s

156 dansyl chromophore as a signaling unit that engages in Forster resonance energy transfer with the in

157 Zr((Mes)PDP(Ph))(2) engages in numerous photoredox catalytic processes and t

158 egardless of the presence of multimorbidity, engaging in a healthier lifestyle was associated with up

159 Participation involved engaging in a semistructured interview and completing a

160 Engaging in altruistic food transfer, instead of keeping

161 ts and classes gained points and rewards for engaging in any activity in or out of school.

162 reased mouth scanning and the Japanese group engaging in greater eye and central face looking.

163 nd during active retrieval from memory while engaging in learned categorization tasks.

164 stress response was not lower in populations engaging in more valuable reproductive attempts.

165 prevent error-prone immature ribosomes from engaging in protein synthesis.

166 Engaging in regular physical activity is one of the most

167 Engaging in such collective action can only build upon t

168 ate that AMPK affects cellular physiology by engaging in the regulation of hiPSC transcription in an

169 The overall engaged-in-care HCV CVL was 4 351 079 copies/mL (standar

170 Viruses naturally engage innate immunity, induce antigen presentation, and

171 A socially engaging instructional style might facilitate imitative

172 Engaging intensivists in antibiotic stewardship program

173 DNA damage engages IRE1alpha signaling in the absence of an endopla

174 "Engage" is a novel, streamlined psychotherapy that relie

175 We conclude that "Engage" is non-inferior to PST.

176 orepressors 1 and 2 (NCoR1/2) is required to engage its catalytic activity(1-3).

177 Thus, vLGN can engage its targets using oscillation-based and conventio

178 ine TNF produced by activated CD4(+) T cells engaged its receptor TNFR on MPs, leading to pro-IL-1bet

179 th essentially depend on the hormone insulin engaging its receptor.

180 ccharide-based compounds bind galectin-8N by engaging its unique arginine (Arg59) and simultaneously

181 mode of binding in which trametinib directly engages KSR at the MEK interface.

182 iation between early encoding processes that engage lateral frontal and sensory regions to successful

183 tamer was modified in such a way that it can engage loop-loop (so-called kissing) interactions with R

184 usiveness of SER activities, for example, by engaging members on issues of D&I through symposia and w

185 eal a mechanism for flexibly and selectively engaging memory retrieval and show that memory-based cho

186 lum (ER) proteostasis network differentially engages misfolded C1163R C-Proalpha2(I) and targets it f

187 ontribute to the complexity of cancer, while engaging modern next-generation sequencing technology to

188 genes and downregulates Major-biased genes, engaging molecular pathways fundamental to foraging beha

189 le-stimulated ATP-hydrolysis by specifically engaging motor domains in the nucleotide-free or ADP sta

190 olve genetic and environmental risk factors, engage multiple cells and tissues, and follow a polygeni

191 ult-to-unfold substrates are released and re-engaged multiple times, with removal of the degradation

192 er dH and vH act in concert or separately to engage NAc representations related to space and reward.

193 unappreciated mechanism through which cells engage nanoporous HA matrix and may represent an importa

194 The PAT complex engages nascent TMDs that contain unshielded hydrophilic

195 -order chromatin and hindrance of mRNPs from engaging nuclear pores.

196 ins localize to the vesicle front and can be engaged on the same vesicle.

197 op that inhibits DSB formation when homologs engage one another.

198 STAT5 and ERK engage opposing biochemical and transcriptional programs

199 Recently CaM was found to engage part of Na(V) 1.5 that is required for channel in

200 We have demonstrated that it is feasible to engage patients awaiting LT in an intensive aerobic exer

201 rtunities for prescribing interventions that engage patients.

202 ce of endogenous PD-L1; (3) PD-L1(+) T cells engaged PD-1(+) macrophages, inducing an alternative M2-

203 ns, such as engaging cargos for transport or engaging peripheral actin to stabilize MTs, suggesting s

204 g across healthcare, we hypothesized that an engaging, personalized therapy may improve adherence and

205 a horizontal ladder while blindfolded, which engaged plantar sensation while minimizing visual compen

206 Young people engage poorly, even obstructively, with conventional hea

207 in 2007 to 2018 in order to inform community-engaged prevention and policy strategies.

208 ions and gamer types (i.e., non-problematic, engaged, problematic and addicted) and (3) the predictiv

209 The Ski complex can engage productively with mRNA and extract it from 80S co

210 tion and Management System (LIMS) called HIV Engaged Research Technology (HEnRY) for implementation i

211 d long CDR-H3 loops into the NA active site, engaging residues highly conserved among IBV NAs.

212 ific network of regulatory elements that p53 engages; reviewing our understanding of how, where, and

213 The notion emerged that self RNAs can also engage RLRs and modulate the IFN-I response, indicating

214 r, U1 snRNP interacts with transcriptionally engaged RNA polymerase II.

215 ions reveals three recurrent circuit modules engaged sequentially to increase locomotor speed.

216 low-level binding of T3SA(-), which does not engage sialic acid.

217 nding of strain T3SA(+), which is capable of engaging sialic acid.

218 We hypothesized that engaging Siglec-E through ST8Sia6-generated ligands may

219 down-regulates the inflammatory response by engaging siglecs.

220 The developed reactions efficiently engage simple bromoarenes and primary sulfamides in betw

221 vely restrains human LINE1s by cooperatively engaging sites in the 5'UTR and stimulating local deposi

222 d, but retains flexibility even in the fully engaged state.

223 gn of small molecule probes that selectively engage structures within disease-causing RNAs, with micr

224 sitoid wasp species have been used in a CURE engaging students at 15 colleges and universities.

225 hen employed in participatory processes that engage study populations, policy makers, and implementer

226 Some functions engaging (subsets of) this area share neurocognitive res

227 tinct, benzyl-protected glycosyl donors were engaged successfully as substrates.

228 the quality of performance measurements, and engage surgeons and all other stakeholders to work toget

229 An ideal glioblastoma treatment needs to engage targets that drive proliferation as well as invas

230 and resistant to forming chemical bonds that engage the 5f shell(1-3).

231 he entire substrate transmembrane domain and engage the active site should provide important tools fo

232 novel intermolecular reactions that directly engage the arene pool.

233 lanine scan of active site constituents that engage the ATP phosphates and the metal cofactors.

234 and promote stalk formation and then acts to engage the distal leaflets of each membrane and promote

235 YAP/TEAD engage the epithelial-to-mesenchymal transition transcri

236 low-cost approach offers a promising path to engage the fiber-shaped single-crystal materials in appl

237 These processes are both known to engage the hippocampus, although whether they share simi

238 herapies aim to kill tumor cells directly or engage the immune system to fight malignancy.

239 ask, a chiral Bronsted acid is added next to engage the isomerization products into a stereocontrolle

240 neurons, but rather how effectively they can engage the motor circuits for ovipositor extrusion.

241 BAF complexes bilaterally engage the nucleosome H2A/H2B acidic patch regions throu

242 pathway-specific transcription factors also engage the phase-separation mechanism for efficient and

243 fingers subdomain-especially the O helix-to engage the primer-template and dNTP triphosphate.

244 d to date, a germline-encoded Trp is used to engage the Pro in NPNA beta-turns, but here the Trp inte

245 etect and destroy proteins that persistently engage the translocon.

246 HSP70 acted by a paracrine mechanism that engaged the Toll-like receptor 4 (TLR4) on hair cells to

247 dings have shown that Vps13 acts after Atg40 engages the autophagy machinery.

248 ion of growth among individual dendrites and engages the autophagy mechanism to sculpt the developing

249 We demonstrate that DR3 engages the canonical and/or non-canonical NF-kappaB pat

250 in the transcription initiation factor that engages the DNA template for RNA priming and growth and

251 Strikingly, Ubqln4 engages the J proteins in a J-domain-independent manner,

252 copy map reveals that the C-edge of betaarr1 engages the lipid bilayer.

253 Rather, the proteostasis network directly engages the misfolded C-Pro domain itself to prevent sec

254 test, suggesting that memory updating in OUL engages the original memory.

255 iquitin revealed three bound ubiquitins: one engages the S1 site, the second binds an S2 site contrib

256 oteome, the surfaceome, is the interface for engaging the extracellular space in normal and cancer ce

257 ding the in vivo pharmacology of novel drugs engaging the GCGR.

258 -21 that inhibited IgE responses by directly engaging the IL-21 receptor on B cells and triggering ST

259 cytotoxicity, has become a central focus for engaging the immune system in the fight against cancer.

260 structure reveals two Galpha(T).GTP subunits engaging the PDE6 hetero-tetramer at both the PDE6 catal

261 Once engaged, the prion reshapes the activity of Snt1 and the

262 How Msp1 selects its substrates and firmly engages them during the energetically unfavorable extrac

263 We discuss how lipid ligands on OMVs engage these pattern recognition receptors on the membra

264 ss and discover that if the network fails to engage this stereotyped regime of motif dominance "cycli

265 origin acts as a PAMP and activates NOS2 by engaging TLR-7.

266 rn how the MD-PFC thalamocortical network is engaged to mediate forms of cognitive control that are s

267 a first-in-human phase I clinical trial and engages TREM2 based on cerebrospinal fluid biomarkers.

268 innate lymphoid cells being explored as they engage tumor cells in different mechanisms compared with

269 ular, the "1-3" bridging mode, in which PRC2 engages two nucleosomes separated by one spacer nucleoso

270 Engaging two transition metal catalysts for this goal pr

271 we investigated the mechanism by which ECT2 engages UBF1 on rDNA promoters.

272 produced by G-OnRamp are effective tools for engaging undergraduates in research and in enabling thei

273 t besides eliciting caspase activation, MOMP engages various pro-inflammatory signalling functions.

274 class B GPCR structures reveals that PACAP27 engages VIP1R with its N-terminus inserting into the lig

275 ity to pioneer novel models that effectively engage virtual participants to advance conference goals.

276 Higher visual cortex was more engaged when expert but not naive animals controlled the

277 , the P300 may reflect an evaluative process engaged whenever a discrepancy between task context and

278 hanisms that restrict excitatory bursts, and engaging wide areas of cortex.

279 Abs elicited with one Salmonella serovar to engage with and consequently provide protection against

280 propriately integrated for us to effectively engage with and learn from our world.

281 The ability of lytic peptides to engage with cell membranes has been exploited for drug d

282 de users with unprecedented opportunities to engage with diverse opinions.

283 we find that misfolded proteins can directly engage with DR5 in the ER-Golgi intermediate compartment

284 cific I domains in part for their ability to engage with multiple ligands and to provide traction for

285 religion and health, epidemiologists need to engage with other aspects of the issue, such as emerging

286 iding opportunities for graduate students to engage with the public, improve their science communicat

287 a wider conversation, allowing clinicians to engage with their feelings, rather than feel ashamed of

288 opy (cryo-EM) structure of Homo sapiens CHD4 engaged with a nucleosome core particle in the presence

289 ctivate or suppress a cellular response once engaged with an antibody-coated target.

290 teasomal decay of miRNA-containing complexes engaged with highly complementary targets.

291 of the arcuate fasciculus were particularly engaged with the quantity and quality of fluent connecte

292 The participants engaged with the remotely administered interventions for

293 y, we determined structures that capture RAG engaged with transposon ends and U-shaped target DNA pri

294 against the SARS-CoV-2 spike protein, which engages with host ACE2 receptor for entry.

295 Nonetheless, the mechanism by which PRC2 engages with native-like chromatin remains incompletely

296 how the PIWI-interacting RNA (piRNA) pathway engages with the membraneless organelle P granule in Cae

297 ement, which includes archaeology, regularly engages with values such as site significance and alloca

298 n regulates MTP expression differentially by engaging with different LEPR types and activating distin

299 r the characteristics of various communities engaging with each preprint on Twitter.

300 ptive immune responses to viral infection by engaging with receptors on immune cells.