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2 cence recovery after photobleaching of cells engineered to express a beta1-GFP fusion protein indicat
6 hase-3beta inhibitor TWS119, and genetically engineered to express a CD19-specific chimeric antigen r
7 ed therapeutically and that allogeneic cells engineered to express a chemorepellent protein would not
8 Adoptive immunotherapies composed of T cells engineered to express a chimeric antigen receptor (CAR)
9 ven single intravenous injections of T cells engineered to express a chimeric antigen receptor (CAR)
11 n followed by autologous T cells genetically engineered to express a chimeric antigen receptor (CAR)
13 The adoptive transfer of autologous T cells engineered to express a chimeric antigen receptor (CAR)
14 ical trial of allogeneic T cells genetically engineered to express a chimeric antigen receptor (CAR)
15 dramatic results have been seen with T cells engineered to express a chimeric antigen receptor (CAR)
19 ibit target cell Akt activity, and KS tumors engineered to express a constitutively activated Akt con
20 lpha(1A)AR stimulation using transgenic mice engineered to express a constitutively active mutant (CA
21 Adoptive transfer of T cells that are gene engineered to express a defined TCR represents a feasibl
22 owing reovirus infection, we used HeLa cells engineered to express a degradation-resistant mutant of
23 null for TGF-beta receptor II (TbetaRII) or engineered to express a dominant-negative Smad3 to atten
24 significantly reduced in S. frugiperda cells engineered to express a double-stranded RNA derived from
26 sm by finding that a L. monocytogenes strain engineered to express a flavinylated extracellular uroca
28 oinfected with viable viruses that have been engineered to express a fluorescent reporter protein dur
29 We demonstrate that a mutation-prone virus engineered to express a foreign gene is an expedient mea
31 Here, we show that DENV can be genetically engineered to express a green fluorescent protein or fir
33 n of sensory experience" in mice genetically engineered to express a human long-wavelength-sensitive
34 across cortical and limbic circuits in mice engineered to express a human loss-of-function depressio
35 e have recently shown that human CD4 T cells engineered to express a human melanoma-associated antige
37 es by transplantation of primary fibroblasts engineered to express a micro-dystrophin/enhanced green
38 the slow-growing M. bovis M. bovis BCG, were engineered to express a model tumor antigen, the K(b)-re
39 lomavirus 16 E7 to knock-in mice genetically engineered to express a mutant form of pRb (pRb(DeltaLXC
40 iler's murine encephalomyelitis virus (TMEV) engineered to express a naturally occurring Haemophilus
41 Here, we demonstrate that NK cells (haNKs) engineered to express a PD-L1 chimeric antigen receptor
44 eport that approximately 10,000 T cells gene-engineered to express a single-chain IL-12 molecule can
46 nce in a polyclonal immune system, mice were engineered to express a superantigen reactive to IgM of
47 eration more directly, we used MCF-10A cells engineered to express a synthetic ligand-inducible form
48 ced prostate cancer with T cells genetically engineered to express a tumor-reactive TCR and a dominan
50 ransgenic or retrovirally transduced T cells engineered to express a tumor-specific T-cell receptor.
54 he safety and activity of autologous T cells engineered to express an affinity-enhanced T cell recept
55 t of a fully competent viral vector backbone engineered to express an antigen from a foreign transgen
57 Highly attenuated KBMA L. monocytogenes were engineered to express an epitope of the melanoma-associa
58 Highly attenuated KBMA L. monocytogenes were engineered to express an epitope of the melanoma-associa
60 human KRAS-dependent colon cancer cell line engineered to express an inducible KRAS-specific shRNA.
61 Ductal and acinar pancreatic cell lines were engineered to express an inducible Mist1 complementary D
62 tologous CD4(+) T cells that are genetically engineered to express an MHC class II-restricted antitum
63 mCherry monomeric red fluorescent protein engineered to express an N-terminal caspase 3 cleavage s
64 Cherry red fluorescent protein recombinantly engineered to express an N-terminal hexahistidine sequen
66 sing substituted peptides and DQ8 constructs engineered to express and present B:9-23 in fixed bindin
67 ncordantly, in human U87MG glioma xenografts engineered to express Ang2, increased expression of MT1-
68 results suggest that lymphocytes genetically engineered to express anti-p53 TCR may be of value for t
69 irus (SIV)-infected animals with CD8 T cells engineered to express anti-SIV T-cell receptor specifici
72 more, GABARAP overexpression in CHO-K1 cells engineered to express AT(1)R increased angiotensin II bi
73 et genes, and mimicked the phenotype of mice engineered to express BCL6 with corepressor binding site
74 received an intravitreal transplant of MSCs engineered to express BDNF and green fluorescent protein
75 In this study, we injected VEEV or WEEV, engineered to express bioluminescent or fluorescent repo
77 iruses, lacking any DNA intermediate, can be engineered to express both coding and noncoding RNAs sug
79 hat pretreatment of mice for 8 h with Nissle engineered to express CAI-1 (Nissle-cqsA) greatly increa
81 OIR mice of hematopoietic stem cells (HSCs) engineered to express CCN1 harnessed ischemia-induced ne
82 expressing endogenous CCR4 and transfectants engineered to express CCR4 were assessed for receptor fu
84 therefore, we determined whether donor VSTs, engineered to express CD19.CAR, retained the characteris
85 generated HLAnull K562 cell clones that were engineered to express CD1d and costimulatory ligands.
86 one marrow progenitors that are retrovirally engineered to express Cdx4 serially replate in methylcel
89 ch approach involves the transfer of T cells engineered to express chimeric antigen receptors (CARs)
93 been observed following transfer of T cells engineered to express chimeric antigen receptors against
94 stration of monoclonal antibodies or T cells engineered to express chimeric antigen receptors or T-ce
95 adoptive cell transfer therapy with T cells engineered to express chimeric antigen receptors or T-ce
96 Adoptive transfer of CD8 T cells genetically engineered to express "chimeric antigen receptors" (CARs
97 (PFC) descending projection neurons in mice engineered to express Chr2 in layer V pyramidal neurons
98 ne (V160) derived from AD169 and genetically engineered to express CMV pentameric complex (gH/gL/pUL1
99 Injection of a canine adenovirus (CAV-2) engineered to express Cre recombinase into the central c
101 ld type (WT) and alpha(1)(0/0) mice and mice engineered to express diazepam-insensitive receptors (al
103 80s of the first transgenic mice genetically engineered to express dominant oncogenes, involving inde
105 rgic (mDA) neurons differentiated from hPSCs engineered to express DREADDs (designer receptors exclus
107 brain cancer using a transgenic mouse model engineered to express E2F1 specifically within glial cel
109 glucose microPET) of glioblastoma xenografts engineered to express EGFRvIII, but not their parental c
111 stem (CNS) was studied, using recombinant RV engineered to express either soluble TNF-alpha [SPBN-TNF
113 drugs, a phenotype exacerbated in cells also engineered to express elevated levels of TbNTR or TbCPR.
114 mating, C. albicans white cells were reverse-engineered to express elevated, opaque-like levels of th
116 ularization in a human prostate cancer model engineered to express enhanced green fluorescent protein
118 with low ESRP1 expression, and PANC-1 cells engineered to express ESRP1 exhibited increased FGFR-2 I
120 apoptosis, Chinese hamster ovary (CHO) cells engineered to express Fc receptors were infected with re
123 outer membrane vesicle vaccines from mutants engineered to express fHbp variants had broad bactericid
124 s using primary human PDAC cells genetically engineered to express firefly- and Gaussia luciferase, s
125 -kappaB (NF-kappaB) activity, although those engineered to express Fmod constitutively exhibited sign
127 sing a versatile transgenic Drosophila model engineered to express G(PA)C in tissues and cells of int
130 tive integrin complexes and that tumor cells engineered to express GEF-deficient GIV fail to transduc
131 tem of Deinococcus radiodurans that has been engineered to express GFP under the control of the recA
132 s and normal hematopoietic stem cells (HSCs) engineered to express Gpx3 short hairpin RNA (shRNA) wer
133 ventricular assist device implantation were engineered to express green fluorescent protein (hCPCe)
134 isolated from embryonic mice transgenically engineered to express green fluorescent protein and tran
135 for clinical trials to evaluate S. gordonii engineered to express group A streptococcal M protein an
136 patient and population scales when TIPs are engineered to express >3-fold more genomic RNA than HIV
138 and V, the excitatory neurons in rat S1 were engineered to express halorhodopsin, a light-sensitive c
139 n between myocytes and syngeneic fibroblasts engineered to express HCN1 pacemaker channels (HCN1-fibr
140 fection with a murine cytomegalovirus (MCMV) engineered to express HEL induced extensive proliferatio
144 eplication-defective VSV can be successfully engineered to express high levels of antigenically authe
145 emonstration that once Bacillus anthracis is engineered to express high levels of SMase C, the result
146 ether human dendritic cells (DC) genetically engineered to express high levels of T-bet (i.e., DC.Tbe
147 with different viral capsids that have been engineered to express high-level, and in some cases hype
152 eric virus HSV-1 17syn+/LAT2, an HSV-1 virus engineered to express HSV-2 LAT, demonstrated that this
155 dministering REGN421 to immunodeficient mice engineered to express human Dll4 inhibited the growth of
156 th of a murine colon adenocarcinoma that was engineered to express human HER2 (CT-26(HER2/neu)) in BA
157 Strikingly, ferret (but not mink) cells engineered to express human HIV-1 entry receptors suppor
159 y generated humanized transgenic mouse model engineered to express human NRG1-IV, an isoform of the N
160 In human papillomavirus transgenic mice engineered to express human papillomavirus type 16 E6 an
162 e and ICOS engagement by tumor cell vaccines engineered to express ICOS ligand enhanced antitumor imm
163 formation in vitro, and B16F melanoma cells engineered to express IGPR-1 displayed extensive angioge
165 ns with corresponding irradiated tumor cells engineered to express IL-4 or GM-CSFs, respectively, as
166 fibroblasts and human astrocytes, which are engineered to express inducible forms of neural reprogra
170 ength transmembrane L1 and a secreted trimer engineered to express its extracellular domain would be
174 tion of KPC mice with Listeria monocytogenes engineered to express Kras(G12D), along with depletion o
175 ty, because primary murine bone marrow cells engineered to express low amounts of BCR-ABL were substa
178 medulloblastoma cell lines (DAOY and UW228) engineered to express miR-520g, a biologically active co
179 by electroporation of synthetic DNA plasmids engineered to express modified human nAbs against multip
180 ion profile of prostate adenocarcinoma cells engineered to express mt-SPOP overlaps greatly with the
181 intratumoral injections of recombinant NDVs engineered to express multiple immunotherapeutic protein
182 id these problems, and miRNA clusters can be engineered to express multiple RNAi effectors, a feature
183 hat dendritic cells (DCs) can be efficiently engineered to express multiple T cell inhibitory ligands
186 imilar observations were made with nematodes engineered to express mutant tat-activating regulatory (
187 locomotor deficit of Caenorhabditis elegans engineered to express mutTDP-43 or mutSOD1 and also prot
191 Here, we show that mouse embryo fibroblasts engineered to express Ndy1 or Ndy2 undergo immortalizati
193 cells stably transfected with the PTH1R and engineered to express NHERF1 under the control of tetrac
196 ll lines and of CTNNBL1 466V/V Ramos B cells engineered to express only CTNNBL1 M466V using CRISPR/Ca
199 nt disease whereas wild-type mice, and those engineered to express only transmembrane TNF (mTNF), ful
200 tem cell differentiation that can be further engineered to express other biochemical cues to control
202 thylotrophic yeast that has been genetically engineered to express over one thousand heterologous pro
204 ited proliferation of R1-11-PCFT4 HeLa cells engineered to express PCFT without the reduced folate ca
205 enhanced Id2 expression into brains of mice engineered to express platelet-derived growth factor in
208 ay increase the therapeutic index of T cells engineered to express powerful activation domains withou
209 e-derived stem cells (ASCs) were genetically engineered to express recombinant secretory human carbox
211 ferred to permissive feline and canine cells engineered to express rhesus and human TRIM5alpha protei
212 ferent attenuated rHPIV1 backbones were each engineered to express RSV F from three different gene po
213 is factor apoptosis ligand (TRAIL) and, when engineered to express secreted recombinant TRAIL, induce
214 non-pathogenic Escherichia coli strains was engineered to express seven potential Cu(2+) binding pep
215 eptide chimera/recombinant modular chimera), engineered to express several autologous T cell epitopes
216 xpression of SFFV gp55 in rodent fibroblasts engineered to express sf-Stk induced their transformatio
218 on with a recombinant -herpes virus, MHV-68, engineered to express SIINFEKL peptide, the ligand for t
220 Ig gene rearrangements from transgenic mice engineered to express single copies of the unrearranged
221 sing this technology, we analyze Ba/F3 cells engineered to express single or multiplexed loss-of-func
222 extended this analysis using retrogenic mice engineered to express single TCR alpha- or beta-chains s
224 t al demonstrated that tumor-tropic bacteria engineered to express specific cancer-related antibodies
225 in vivo, we introduced human DCIS cell lines engineered to express specific genes into a "mammary int
227 by mammary epithelial cells and kidney cells engineered to express SV40 early region proteins, hTERT,
229 cultivation with Chinese hamster ovary cells engineered to express T-cadherin on their surface as com
230 al address the biology and safety of T cells engineered to express T-cell receptor (TCR) variants end
231 on experiments using B. pseudomallei strains engineered to express T6SS-5 in vitro show that the VgrG
233 ibed a murine embryonic stem cell (ESC) line engineered to express the activated Notch 4 receptor in
234 functional characteristics of CD4(+) T cells engineered to express the alpha- and beta-chains of a hi
235 esponse to endorepellin in cells genetically engineered to express the alpha2beta1 integrin, but not
237 clostridial strain C. sporogenes genetically engineered to express the E. coli-derived cytosine deami
238 ration of a vesicular stomatitis virus (VSV) engineered to express the endogenous melanocyte antigen
239 l-arabinofuranoside ([(125)I]FIAU) to tumors engineered to express the Epstein-Barr virus thymidine k
241 l in neurophysiological research, which were engineered to express the green fluorescent protein (GFP
242 y, influenza viruslike particles (VLPs) were engineered to express the hemagglutinin (HA) and genes f
244 hanced in cells lacking p53, including those engineered to express the HPV16-E6 oncoprotein or short
246 iously, we demonstrated that transgenic mice engineered to express the human GLUT4 gene under the con
248 on-pathogenic bacteria, has been genetically engineered to express the III7-10 fragment of human fibr
250 ansformed mouse mammary cells that have been engineered to express the inducible oncogenic transgenes
251 examined uptake dynamics of Escherichia coli engineered to express the invasin surface receptor from
252 e optical stimulation of neurons genetically engineered to express the light-gated ion channel channe
253 found that unpolarized CD4(+)CD25(-) T cells engineered to express the MART-1(27-35) TCR selectively
254 isting of allogeneic pancreatic cancer cells engineered to express the murine alpha(1,3)GT gene.
255 nd adoptive transfer of monocytic cell lines engineered to express the mutant CD13 were severely impa
256 kin mouse models in which endogenous Jup was engineered to express the Naxos-associated form of plako
258 /Rpr, in which the MRE-16 strain of SINV was engineered to express the proapoptotic gene reaper from
259 RIG-I) or after infection of cells that were engineered to express the reovirus sigma3 double-strande
260 in cell lines and primary bone marrow cells engineered to express the respective tyrosine kinase all
261 were aged, treated with N-acetylcysteine, or engineered to express the ROS scavenger catalase specifi
266 Arabidopsis through Pseudomonas fluorescens, engineered to express the type III secretion system, als
267 0-fold when the virus was grown on FRT cells engineered to express the UL20 gene in comparison to the
268 utant as a backbone, new mutant viruses were engineered to express the wild-type (WT) V protein (+V-w
270 , in which a stable murine DC line XS106 was engineered to express the yellow fluorescent protein (YF
273 ls, which possess MLG but lack MXE, might be engineered to express this Equisetum enzyme, thereby enh
277 ted with strains of single-cycle SIV (scSIV) engineered to express three different envelope glycoprot
278 in vivo A LGR5-rainbow (LBOW) mouse line was engineered to express three different LGR5 isoforms alon
279 ivation of both human embryonic kidney cells engineered to express TLR2 (HEK-TLR2) and wild-type (WT)
281 erentially replicate in tumour cells, can be engineered to express transgenes that augment their cyto
283 phorylation of these kinases in 2 cell lines engineered to express TSHRs, human embryonic kidney HEK-
284 nerated during infection with vaccinia virus engineered to express TSKB20 were approximately 2.5-fold
287 system is derived from an HIV proviral clone engineered to express two different fluorescent proteins
288 We examined the activity of human T cells engineered to express variants of a single TCR (1G4) spe
290 f-VEGF function approach with skeletal MDSCs engineered to express VEGF or soluble Flt1, a VEGF-speci
293 xpress low endogenous levels of MT1-MMP were engineered to express wild-type MT1-MMP, a phosphomimeti
296 bone injury, we found that MSCs genetically engineered to express Wnt-4 enhanced osteogenesis and im
297 asmodium falciparum were purified from yeast engineered to express "yeast optimized" pfcrt genes, rec
299 he feeder cell line was selected in G418 and engineered to express zebrafish leukemia inhibitory fact
300 ish ovarian feeder cell line (OFC3) that was engineered to express zebrafish Lif, Fgf2 and Gdnf.