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1 invasive tumors more likely to successfully engraft.
2 transplanted subcutaneously alone failed to engraft.
3 All recipients of TN-depleted PBSCs engrafted.
4 enated rewarming (COR) for 90 minutes before engrafting.
7 daptive and natural killer immune cells, can engraft a wide array of human cancers at 37 degrees C, a
9 ma cell lines and patient-derived xenografts engraft and adopt a metastatic program in chick embryos.
11 f TECs, and further show that young TECs can engraft and directly drive the growth of involuted thymu
12 ury can recruit BM progenitors of LSECs that engraft and fail to fully differentiate, which creates a
14 human glial progenitor cells (hGPCs) densely engraft and myelinate the hypomyelinated shiverer mouse.
16 y of its haematopoietic stem cells (HSCs) to engraft and reconstitute the blood and bone marrow of an
17 ly that self-assembled allogeneic constructs engraft and reject similar to allogeneic skin despite th
19 CD33 in HSPC doesn't impair their ability to engraft and to repopulate a functional multilineage hema
20 1 infection, these coreceptor negative cells engraft and traffic normally, and are protected from inf
21 At day 100, 35 (92%) of 38 patients were engrafted and alive in the cyclophosphamide 50 mg/kg coh
22 irradiated mice, in which they successfully engrafted and differentiated into hematopoietic progenit
27 When injected into dystrophic mice, MiPs engrafted and repaired both skeletal and cardiac muscle,
28 The findings indicated that transplanted KC engrafted and survived in recipient livers throughout th
29 se data demonstrate that genome-edited HSPCs engraft, and contribute to multilineage repopulation aft
30 n assays, we show that HSCs emerge, migrate, engraft, and differentiate in the absence of cdh5 expres
33 trocytes in humanized glial chimeric mice by engrafting astrocytes differentiated from human-induced
36 (-)CD34(+)CD38(lo) stem cell population, and engrafted B-1 cells in humanized mice exhibit an Ig-usag
41 ve hematopoiesis and production of long-term engrafting CD34+ cells, suggesting these ligands are cri
42 or reduced subcutaneous tumor growth in mT3 engrafted Cdh11(+/+) mice when given in combination with
44 ent, significantly induced GFP expression in engrafted cells across tissues, reflecting viral reactiv
47 ed control of graft function, and activating engrafted cells drives behavioral changes in transplante
51 rom human embryonic stem cells and show that engrafted cells replenish depleted precursor numbers, ge
54 s representation of spatial distributions of engrafted cells, enabling simulation of clinical therapy
58 ation, and that this loss can be reversed by engrafting cells back into an intact CNS environment.
65 d onto infarcted, immune tolerant rat hearts engrafted, displayed both host and graft-derived vascula
66 week post-infarct immune tolerant rat hearts engrafted, displayed evidence for host vascular coupling
68 r effect of AlloSCT is due to the ability of engrafting donor derived lymphocyte populations to eradi
69 repertoire in hematochimeric mice, although engrafted edited clones preserve multilineage and self-r
70 d macrophages that develop during injury can engraft efficiently in the pool of resident peripheral n
73 e islet seeding, the scaffold was allowed to engraft for 28 days to allow the tissue response to damp
76 ter BC treatment, multiple cell types can be engrafted from fresh or cryopreserved testicular cells,
78 blood disorders, although its application in engrafting hematopoietic stem cells (HSCs) remains unexp
82 AGM AKT-ECs specified into long-term, adult-engrafting HSCs, establishing that a vascular niche is s
83 this aneuploidy peak: rapid expansion of the engrafted HSPC population and bone marrow microenvironme
84 e percentage of multipotent HSPCs within the engrafted HSPC population was significantly decreased co
87 ransgenic mice and immunodeficient mice with engrafted human CD34(+) cells that HSPCs transduced in t
88 in a NOD/SCID/IL2Rgamma(-/-) mouse model of engrafted human chronic myelogenous leukemia, we now dem
92 a greater capacity to form spheroids and to engraft immune-deficient mice than did ROR1-negative (RO
93 agocytic myeloid cells in vitro and can also engraft immunodeficient mice, generating myeloerythoid a
97 lished human HD glial chimeras by neonatally engrafting immunodeficient mice with mutant huntingtin (
98 results in their apoptosis and inability to engraft, implicating HIF-1alpha or HIF-2alpha as therape
99 characteristics and have been shown able to engraft in and repopulate both animal and human livers.
100 ory properties of IFP-MSC, which selectively engraft in areas of active synovitis/IFP fibrosis induci
104 that are derived from only 50 cells robustly engraft in recipient mice without the normal requirement
110 ouse colon organoids and human CRC organoids engraft in the distal colon and metastasize to the liver
111 Because few intravenously administered MSCs engraft in the myocardium, studies have mainly utilized
113 rogenitor cells (HSC/Ps) fail to effectively engraft in transplantation experiments, exhibiting norma
115 argeting and can form nephron organoids that engraft in vivo, functionally couple to the host's circu
118 tion of human hematopoietic progenitor cells engrafted in immune deficient mice (huNSG) results in vi
125 ifferentiated from hESCs and hiPSCs could be engrafted in the liver parenchyma of immune-deficient tr
126 nted adult KC were successfully targeted and engrafted in the liver with retention of innate immune a
133 bone marrow-derived circulating EPCs do not engraft into blood vessels, but that such circulating ce
134 d with light-inducible NPs containing RA can engraft into bone marrow in vivo in the proximity of oth
136 last ability to cross the vessel wall and to engraft into damaged myofibres through the modulation of
137 re colony-forming-cell potential and durably engraft into immune-deficient mice after primary and sec
138 freshly isolated hBTSCs were equally able to engraft into immunocompromised mice yielding cells with
140 we document that human MiPs can successfully engraft into the skeletal muscle and hearts of dystrophi
145 r inflammation was induced in human arteries engrafted into immunodeficient mice that were reconstitu
146 del of TNBC in which Eo771/MUC1-C cells were engrafted into MUC1 transgenic mice, we showed that targ
147 a mouse model in which human glial cells are engrafted into neonatal mice that are both immunodeficie
149 Finally, patient-derived xenografts could be engrafted into our model, opening new avenues for develo
151 l of liver failure, the rat liver stem cells engrafted into the host liver where they differentiated
152 ter ocular injury in mice become permanently engrafted into the tissue, establishing a proinflammator
153 disease phenotype to normal mice, since mice engrafted intrastriatally with mHTT hGPCs exhibit worse
154 e first hematopoietic stem cells (HSCs) that engraft irradiated adult mice arise in the aorta-gonad-m
155 ent of human C-peptide indicated that higher engrafted islet mass resulted in higher human C-peptide
157 ging yielded high resolution images of liver-engrafted islets and also showed significant retention i
160 t developed collapsing glomerulopathy in the engrafted kidney, which was transplanted from a donor wh
162 ogenesis of myeloproliferative neoplasms, we engrafted lethally irradiated recipient mice with bone m
163 now demonstrate the complete elimination of engrafted leukemia after only one course of combined che
167 However, glycoengineered hiPS-HSPCs did not engraft long-term, indicating that additional functional
168 nted onto rat hearts, cardiopatches robustly engraft, maintain pre-implantation electrical function,
169 types of genetically MC-deficient mice after engrafting MCs that either do or do not express TNFRSF14
170 ry methods that can effectively localize and engraft mesenchymal stem cells (MSCs) with high disease-
171 rgen-specific gut inflammation in human PBMC-engrafted mice can be avoided by enhancing the numbers o
173 and improves the survival of orthotopically engrafted mice implanted with human PTEN-deficient gliom
179 early 2000s, investigators have been able to engraft murine recipients with human hematopoietic stem
182 aematopoietic stem and progenitor cells that engraft myeloid, B and T cells in primary and secondary
183 viding a supply of bone marrow-derived brain-engrafting myeloid cells with donor wild-type CSF1R to r
185 READD-dependent stimulation or inhibition of engrafted neurons, revealing D1 receptor-dependent regul
188 Modified cells maintained their ability to engraft NOD/SCID/IL2rgamma(null) mice and to produce cel
191 the survival, maturation, and integration of engrafted NSC/NPCs as a restorative treatment for PD.
192 3A-APC-potentiated neuronal recruitment from engrafted NSCs might offer a new approach to the treatme
193 Overall our results demonstrate that PBMC-engrafted NSG models are rapid, sensitive, and reproduci
195 Here, using human haematopoietic stem cell-engrafted NSG-HLA-DQ8 transgenic mice, we provide direct
197 or prognostic AMLs or for samples capable of engrafting NSG mice compared with good risk AMLs or none
199 In both SK-N-AS and BE(2)C cell lines, when engrafted on the chorioallantoic membrane of chick embry
201 nced the activity of anti-ErbB2 mAb to treat engrafted or spontaneous tumors as well as lung metastas
205 hemoglobin and resolution of hemolysis among engrafted patients were accompanied by stabilization in
210 -) cells give rise to all blood lineages and engraft primary and secondary immunodeficient mice.
211 establish persistent replication in vivo, we engrafted primary rhesus macaque hepatocytes into immuno
214 omy (PH), transplanted stem/progenitor cells engrafted, proliferated competitively compared to host h
215 t intravenously injected rhC7 distributed to engrafted RDEB skin, incorporated into its dermal-epider
220 In addition, we will discuss the safety of engrafted stem cell-derived OPCs, as well as approaches
222 was no predictable relationship between the engrafting subclone and the evolutionary hierarchy of th
223 o efficacy of (212)Pb-daratumumab, mice were engrafted subcutaneously with 5 x 10(6) RPMI8226 cells.
224 o efficacy of (212)Pb-Daratumumab, mice were engrafted subcutaneously with 5.106 RPMI8226 cells.
225 R-deficient PDAC cells lacked the ability to engraft successfully in immunocompromised mice, but IDH1
227 ted and on which proteins of interest can be engrafted thanks to widely used genetic tagging strategi
229 data indicate that peripheral monocytes can engraft the meninges after an inflammatory challenge, im
230 e infiltrated by inflammatory monocytes that engrafted the meningeal niche and remained in situ for m
235 lungs of human CD34+ hematopoietic stem cell engrafted virus-infected NOD.Cg-Prkdc(scid) Il2rg(tm1Wjl
237 -corrected SCD HSPCs retained the ability to engraft when transplanted into non-obese diabetic (NOD)-
238 large cohort of patient samples successfully engrafted, which covered all of the important genetic an
239 cantly improved behavioral disease outcomes, engrafted widely into capillaries of the gray/white matt
240 prolonged the lifespan of C57BL/KaLwRij mice engrafted with 5TGM1-luc myeloma, an effect comparable t
242 cells was confirmed in immunodeficient mice engrafted with a human AML cell line expressing DeltaNPM
243 blished an S. aureus infection model in mice engrafted with a human immune system, compared it with i
244 seventeen patients with MPS-IH successfully engrafted with a median follow-up age of 9.2 years were
245 ist of a tumor antigen-specific Fab molecule engrafted with a peptide neo-epitope, which is bound exc
249 eukemia burden and improved survival of mice engrafted with BETi-P/R sAML cells or patient-derived AM
250 a decrease in growth kinetics, whereas mice engrafted with Bim knockout tumors showed no reduction i
251 Hypercholesterolemia-prone mice that were engrafted with bone marrow obtained from homozygous or h
252 In vivo biodistribution studies in mice engrafted with breast tumors showed a distinct accumulat
255 , we show that humanized mice, i.e., animals engrafted with components of a human immune system, that
264 e lymphomas when directly injected into mice engrafted with human fetal CD34+ cells and human thymus.
265 era) Il2rgamma(tm1hera) (SRG) rat models, co-engrafted with human full-thickness fetal skin, autologo
266 type EBOV (Makona variant) infection of mice engrafted with human hematopoietic CD34(+) stem cells (H
267 e current study, we inoculated NSG-SGM3 mice engrafted with human hematopoietic CD34+ stem cells with
269 Non-obese diabetic-scid IL2rgammanull mice engrafted with human hematopoietic stem cells (hu-SRC-SC
270 human peripheral blood mononuclear cells or engrafted with human hematopoietic stem cells [human imm
273 Fah (-/-), Rag2 (-/-), and Il2ry (-/-) mice engrafted with human hepatocytes (hFRG mice) and rhesus
274 rg(-/-)Sirpa(NOD)Alb-uPA(tg/tg) mice, stably engrafted with human hepatocytes (HUHEP) with or without
277 ull)SCF/GM-CSF/IL3 (NSG-SGM3) strain of mice engrafted with human thymus, liver, and hematopoietic st
278 d that NOD/SCID/gamma(C) (-/-) c-kit(+) mice engrafted with human tissues 1 day after birth (designat
280 natal immune compromised mice after they are engrafted with human umbilical cord blood stem cells.
281 olitinib or PU-H71 improved survival of mice engrafted with JAK2V617F-mutant, Tp53-deficient AML, dem
282 Aspergillus fumigatus when mice were heavily engrafted with leukemia cells, had severe chemotherapy-i
283 murine transplant models and humanized mice engrafted with LV-modified HSCs show high levels of LV e
284 1-Kit(W/W-v) or C57BL/6J-Kit(W-sh/W-sh) mice engrafted with mast cells that did or did not express VD
287 rdingly, when infused in NSG mice previously engrafted with myeloma, SE cells mediated tumor rejectio
289 miR-155) in human lymphoma cell lines, mice engrafted with patient-derived xenografts (PDXs), and DL
290 ogeneic PBMC and were more severe in animals engrafted with PBMC depleted of CD4(+)CD25(high) cells.
291 lung inflammation, immunodeficient mice were engrafted with PBMCs from these allergic donors plus the
292 ficient NOD/SCID/IL-2Rgamma(null) (NSG) mice engrafted with peripheral blood cells from patients with
296 xicity in the humanized NOD/SCID mouse model engrafted with red blood cells from G6PD deficient donor
297 c CAR T cells infused in Nod scid gamma mice engrafted with the human melanoma WM115 cell line have s
299 C-deficient Kit(W-sh/W-sh) mice systemically engrafted with WT and CRF(2)(-/-) BMMCs demonstrated the