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1      Indeed, in many regards, pRB remains an enigma.
2  phosphatase induces oncogenesis has been an enigma.
3  our framework provides clues regarding this enigma.
4 n the interseismic period is a long-standing enigma.
5 es in the sub-RPE space, however, remains an enigma.
6  dimer of STING represents a physicochemical enigma.
7 nisms generating PC-containing EVs remain an enigma.
8 ecretion of these antibodies has remained an enigma.
9  that its functional significance remains an enigma.
10 strength, leaving the core dynamo process an enigma.
11 nomenology and mechanisms involved remain an enigma.
12 s or populations of reservoir bats remain an enigma.
13 ed, these substances are mysteries within an enigma.
14 f the faculty of language largely remains an enigma.
15 lipping this giant substrate has remained an enigma.
16 he catalyzed chemical conversion is still an enigma.
17 s unusual structural feature has remained an enigma.
18 re, we review the literature and resolve the enigma.
19 hanism of this allelic exclusion has been an enigma.
20 -catenin activity in these events remains an enigma.
21 ose of this remarkable structure has been an enigma.
22  within the cytoplasm remains somewhat of an enigma.
23  change in calcium gradient have remained an enigma.
24 mor angiogenesis and tumor growth remains an enigma.
25 heir poor splicing, has been a long-standing enigma.
26 sweet potato in the Pacific has long been an enigma.
27 ent pulses of technological innovation is an enigma.
28 s, peripartum cardiomyopathy has remained an enigma.
29 tization to food antigens largely remains an enigma.
30  lipids to benefit its infection is still an enigma.
31 ogical basis for Mn(II) oxidation remains an enigma.
32   Nevertheless, how they function remains an enigma.
33 affected, the etiology of flushes remains an enigma.
34 nisms that underlie their activity remain an enigma.
35 the earliest urban civilizations, remains an enigma.
36 hhK in pantothenate biosynthesis remained an enigma.
37 nsible for its biosynthesis have remained an enigma.
38  discern misfolded proteins has long been an enigma.
39 zed to a nascent RNA transcript, has been an enigma.
40 tes, but their occurrence in metazoans is an enigma.
41 nucleotides to ribosome activity is one such enigma.
42 ymphocyte responses has been a long-standing enigma.
43 d substances, is a millennia-old nutritional enigma.
44 antimony-decolourised Roman glass remains an enigma.
45 ver its function in hematopoiesis remains an enigma.
46  bodies, cilial function(s) long remained an enigma.
47 warming in the Northern Hemisphere remain an enigma.
48 on, and thus the pathogenesis of TRAPS is an enigma.
49 uninfected or HCMV-infected cells remains an enigma.
50 nd how transcription is initiated remains an enigma.
51 r precise role in membrane fusion remains an enigma.
52        For other disparities, they remain an enigma.
53 cytes in Tat-mediated amyloidosis remains an enigma.
54  hibernation or similar behaviors remains an enigma.
55 isual fixation, can drive illusory motion in Enigma.
56 sects, yet the origin of the pupa remains an enigma.
57 or equilibrium can explain this evolutionary enigma.
58 d enzyme activity in NendoUs has remained an enigma.
59 ism for exercise hyperaemia is a century old enigma.
60  in a hitherto uncharacterized gene we named Enigma.
61 e unique human brain remains an evolutionary enigma.
62 terium tuberculosis has been a long-standing enigma.
63 c position of the giant deer has remained an enigma.
64 tion of Hassall's corpuscles has remained an enigma.
65 e spongiform encephalopathy (BSE) remains an enigma.
66 protein to B-cell immortalization remains an enigma.
67 mus-independent type 2 Ags is an immunologic enigma.
68 LD) senses unfolded proteins has remained an enigma.
69 oosing what we look at, but has long been an enigma.
70 main of TFPI-alpha, however, has remained an enigma.
71  found in all PC-1 family members remains an enigma.
72 t in eukaryotic membranes remains largely an enigma.
73  GSH transferase superfamily has remained an enigma.
74 eted for ubiquitin conjugation is largely an enigma.
75 se mechanism of allelic exclusion remains an enigma.
76  of serum ferritin, its secretion remains an enigma.
77 pass membrane filter of the cell, remains an enigma.
78 ns and symbionts, has remained an unresolved enigma.
79  enrichment in prostate carcinoma remains an enigma.
80 how force might be generated has remained an enigma.
81  function of motor cortex continues to be an enigma.
82  resultant increase in firing rate remain an enigma.
83 nhibitory Mdm2 isoforms in tumors remains an enigma.
84 mong vertebrates and remains a developmental enigma.
85 erent species and tissues is a long-standing enigma.
86  but its preference for this site remains an enigma.
87  capacity is lost in adult humans remains an enigma.
88 hrough the known biology and has remained an enigma.
89 mplex and heterogeneous condition remains an enigma.
90 cript to have variable expression remains an enigma.
91 anisms that catalyze its formation remain an enigma.
92 tween rod and cone channels has long been an enigma.
93 iation therapy have elucidated parts of this enigma.
94 e signaling hub(s) involved have remained an enigma.
95  proteins, their existence in RNA remains an enigma.
96 e dynamic process of CE, however, remains an enigma.
97 esults from the imaging genomics consortium, ENIGMA.
98  its progeny, and therefore, P10 presents an enigma.
99 nisms of this communication have remained an enigma.
100         Congenital heart disease (CHD) is an enigma.
101 ve effect on fitness remains an evolutionary enigma.
102 al genetics, the T/t complex and its genetic enigmas.
103 rge multicenter neuroimaging cohort from the ENIGMA 22q11.2 Deletion Syndrome Working Group.
104                                However, many enigmas about the molecular mechanisms involved remain u
105   Through the formation of the international ENIGMA ADHD Working Group, we aimed to address weaknesse
106                                       In the ENIGMA-ADHD sample, lower surface area values were found
107 ldren, adolescents, and adults separately in ENIGMA-ADHD, a consortium of 36 centers.
108 nistic bases for this specificity/degeneracy enigma and also compare and contrast Ag recognition by A
109 ion and the perception of illusory motion in Enigma and rule out the hypothesis that the origin of th
110 es in almost 40,000 individuals from CHARGE, ENIGMA and UK Biobank.
111 hropoietin (Epo) have been until recently an enigma, and abnormality in the hypoxia-sensing pathway h
112            Among possible resolutions of the enigma are: a substantial reduction from traditional est
113 ti-loci interactions remains something of an enigma as beyond low-resolution DNA FISH we do not have
114 chanism(s) enhancing its formation remain an enigma because abiotic dolomite has been challenging to
115 rangement of Ig H and L chain genes poses an enigma because both processes use the same recombinatori
116 ied whereas the function of AcpT has been an enigma because no carrier protein substrate could be fou
117 rents on brain oscillations have remained an enigma because of the inability to record them simultane
118 ated lactone moiety of PLMs has presented an enigma because the predicted dehydratase domain in modul
119 ls for renal transplant recipients remain an enigma because there are no adequate randomized controll
120  utility of these replacements represents an enigma because they yield no improvements in the affinit
121 ss to copper bioavailability has remained an enigma, because copper metalloproteins are prevalent and
122 f these receptors still remain a tantalizing enigma, because numerous previous attempts at the large-
123 to 347 in the C-terminal region, has been an enigma, because the basis for its transformation defect
124 hese systems not only explain a longstanding enigma but also provide guidelines for further studies t
125          The precise role of NPY has been an enigma, but a recent study provides a breakthrough, demo
126   The pathophysiology of fibrosis remains an enigma, but considerable research and debate surrounds t
127  has always been a suspect for this clinical enigma, but the exact mechanisms have been unclear.
128                              We analyze this enigma by considering that amorphous silicas present two
129 cing studies in mice to further clarify this enigma by investigating LMC progenitor contribution to P
130                       Here we show that this enigma can be resolved by introducing a critical scaling
131 cale genetic and clinical resources from the ENIGMA, CIMBA and BCAC consortia to assess pathogenicity
132 in Magnetic Resonance Imaging collaboration, ENIGMA-CNV.
133                        While deciphering the Enigma code, Good and Turing derived an unintuitive, yet
134  summary statistics of putamen volume in the ENIGMA cohort, a total of 15 independent significant SNP
135 nhancing NeuroImaging through Meta Analysis (ENIGMA; combined n >= 23,723).
136 esonance imaging (MRI) results from the ADHD ENIGMA Consortium (subcortical MRI n = 3242; cortical MR
137                                          The ENIGMA consortium conducted genome-wide association stud
138 ers using structural brain imaging data from ENIGMA consortium data.
139     Large-scale brain imaging studies by the ENIGMA Consortium identified structural changes associat
140 7 healthy participants from 11 participating ENIGMA Consortium sites.
141 er neuropsychiatric disorders studied by the ENIGMA consortium, significant convergence was observed
142  meta-analysis of available data through the ENIGMA Consortium, using a common analysis pipeline, to
143 tely independent of a study performed by the ENIGMA consortium, we conducted a large-scale multisite
144 ric changes in schizophrenia reported by the ENIGMA consortium.
145  control participants from 13 cohorts in the ENIGMA consortium.
146 ntrols, from 54 independent data sets of the ENIGMA consortium.
147  quality-control pipeline established by the ENIGMA consortium.
148 euro Imaging Genetics through Meta-Analysis (ENIGMA) Consortium and two year hippocampal volume chang
149 Neuroimaging Genetics through Meta-analysis (ENIGMA) Consortium is a global team science effort, now
150 Neuroimaging Genetics through Meta-Analysis (ENIGMA) consortium.
151 sphingolipids for over a century because new enigmas continue to surface.
152 ul illusory motion perceived in the painting Enigma, created by op-artist Isia Leviant.
153 ce of well powered longitudinal studies, the ENIGMA cross-sectional sample across six decades of ages
154 ns in an ATN-1(alpha-actinin)- and ALP-1(ALP/Enigma)-dependent manner, where it contributes to the or
155 ular basis for biosynthesis of 1 had been an enigma despite the availability of the A. fumigatus geno
156 ing harmonization protocols developed by the ENIGMA-DTI working group, we identified widespread reduc
157 ructural mechanism of AGE recognition was an enigma due to the diversity of chemical structures found
158 ed Ca(2+)-selective channels has remained an enigma, due largely to the continued inability to convin
159                                 We show that Enigma encodes a mitochondrial protein with homology to
160 le brain research collaborations such as the ENIGMA (Enhancing Neuro Imaging Genetics through Meta An
161 nts from 11 mega- and meta-analyses from the ENIGMA (Enhancing Neuro Imaging Genetics Through Meta An
162    To address these issues, we developed the ENIGMA (Enhancing Neuro Imaging Genetics Through Meta-An
163 sent the largest ever worldwide study by the ENIGMA (Enhancing Neuro Imaging Genetics through Meta-An
164                   Enigma subfamily proteins (Enigma, Enigma homolog protein, and Cypher) of the PDZ-L
165                                              ENIGMA-Epilepsy is a large quantitative brain imaging co
166 rt of water across epithelia has remained an enigma ever since it was discovered over 100 years ago t
167     Saturn's largest moon, Titan, remains an enigma, explored only by remote sensing from Earth, and
168 NeuroImaging Genetics through Meta-Analysis (ENIGMA) findings.
169 steep energy barrier is overcome has been an enigma for a long time.
170  of Galactic cosmic-ray ions has remained an enigma for almost a century.
171 esis of Crohn's disease (CD) has remained an enigma for at least a century.
172  localization of these sites has remained an enigma for decades.
173  these nodule types has been a long-standing enigma for molecular and evolutionary biologists.
174 er synthesis by two catalytic centers was an enigma for over three decades.
175 his reason that superconductivity remains an enigma for scientists for over a century after Kammerlin
176 re as on its leading hemisphere, has been an enigma for three centuries.
177 ow neurons instantiate conscious states), an enigma for various disciplines.
178 cterial order Bacillales, yet they remain an enigma from both functional and phylogenetic perspective
179 sent a molecular and genetic analysis of ALP-Enigma function in C. elegans.
180 ans provides an excellent model to study ALP-Enigma function.
181    Across the subcortical regions studied by ENIGMA, gene expression profiles for three pathways were
182                                         This enigma has been a major obstacle to a full understanding
183                                  A long-term enigma has been how injury leads to dedifferentiation.
184                               A longstanding enigma has been the origin of maternal centrosomes that
185 re we show that the actin-associated protein enigma homolog (ENH) is a cytoplasmic retention factor f
186     Here we show that a PKC binding protein, enigma homolog (ENH), interacts specifically with both P
187 d reduced a cytoskeleton-associated protein, Enigma homolog 1 (ENH1), and its downstream transcriptio
188 tion of striated muscle, whereas the role of Enigma homolog protein (ENH) in muscle remains largely u
189                       We studied the role of Enigma homolog protein in the heart using global and car
190           Enigma subfamily proteins (Enigma, Enigma homolog protein, and Cypher) of the PDZ-LIM domai
191                  It has been a long-standing enigma how different IDRs successfully execute their spe
192                        It is a long-standing enigma how glycogen storage disease (GSD) type I patient
193                               It has been an enigma how Na,K-ATPase discriminates between Na(+) and K
194                          We are left with an enigma: how can the FtsZ protofilament, which appears to
195 r (501)NGR to iso-DGR possibly explains this enigma, i.e. ligation of iso-DGR by alphavbeta3 integrin
196 o previous study has directly correlated the Enigma illusion to any specific physiological mechanism,
197 r complexity of eukaryotes represent a major enigma in biology.
198                               One celebrated enigma in cardiac evolution involves the transition from
199       These findings address a long-standing enigma in cell biology and provide targets to engineer o
200 gh-valent enzymatic intermediates remains an enigma in chemical catalysis.
201 Africa and Asia - represents a long-standing enigma in ecology.
202                                    A central enigma in epigenetics is how epigenetic factors are guid
203  but their origin has remained an unresolved enigma in palaeontology since the nineteenth century(2-4
204                              Revisiting this enigma in Saccharomyces cerevisiae, we found that the re
205 for deciphering the long-standing structural enigma in self-assembled monolayers (SAMs).
206                           Here I review this enigma in some detail, identifying several evolutionary
207                                           An enigma in studies of neuropsychiatric disorders is how t
208 Hemoglobin (Hb) E (beta-Glu26Lys) remains an enigma in terms of its contributions to red blood cell (
209  to occur in diverse viruses, SIE remains an enigma in terms of key molecular determinants and action
210      gammadelta T cells are an immunological enigma in that both their function in the immune respons
211 ssing heritability', which has emerged as an enigma in the post-genome-wide association studies (GWAS
212 ric disorders are among the most intractable enigmas in medicine.
213 3, have both fueled new insights and exposed enigmas in our understanding of the iconic p53 tumor sup
214 wall extension endures as one of the central enigmas in plant cell morphogenesis.
215 eceptors (ORs) constitute one of the biggest enigmas in the field.
216            Most proposals for resolving this enigma invoke additional players, such as lipid rafts or
217                                          The enigma is epitomized by loggerhead sea turtles (Caretta
218                       Solving this infection enigma is important clinically, for diagnosis, prognosis
219                                    A central enigma is that host immunity is necessary to control dis
220                                      Another enigma is the replacement of existing strains during a g
221       A necessary step toward resolving this enigma is to define the cell types in which mHTT express
222 ated species - however, for many genera this enigma is yet to be satisfactorily explained.
223 in primary biliary cirrhosis (PBC) remain an enigma, it has been suggested that the pathology is medi
224 nditions and environmental constraints is an enigma known as "the phosphate problem." Here we show th
225 = 6420) and genetic data (n = 3907) from the ENIGMA Major Depressive Disorder (MDD) working group.
226 ring these times, this long-standing climate enigma may be solved.
227 n 952 male and 1236 female controls from the ENIGMA MDD working group.
228                       The performance of the Enigma MiniLab assay for influenza A and B viruses and r
229  patients with BD to date, collected via the ENIGMA network.
230  of shared epitope-RA association remains an enigma, observations made during the last year shed new
231 rols across 37 datasets participating in the ENIGMA-OCD Working Group, we calculated intra-individual
232                                          The enigma of carotenogenesis in the absence of light (e.g.
233 de important insights into the long-standing enigma of CCA regulation and complete the first descript
234  as a potential solution to the evolutionary enigma of co-existing host-specific races (or 'gentes')
235 nses, and may bear relevance to the clinical enigma of greater MS susceptibility in women but faster
236 sed whole-genome sequencing and resolved the enigma of how such complex phenotypic differences can ha
237          This provides an explanation of the enigma of how, in different species, globin genes linked
238 ility to produce normal eggs remains a great enigma of human biology.
239 tential possibilities to shed light into the enigma of Maurer's clefts.
240                                           An enigma of mild traumatic brain injury are observations o
241                                           An enigma of modern medicine has persisted for over 150 yea
242 e-like effector differentiation is a central enigma of NKT cell development.
243 ologies potentially aiding in clarifying the enigma of plant lignification.
244                                      A major enigma of primary biliary cirrhosis (PBC) is the selecti
245          Male infertility is a long-standing enigma of significant medical concern.
246                                          The enigma of Sizzled, a secreted Frizzled-related protein,
247 esent study provide a solution to address an enigma of the CRP system, namely, the 3 orders of magnit
248                                    A central enigma of the cytolytic mechanism of the CDCs is that th
249 al point in their phase diagram is a central enigma of the high-temperature superconducting cuprates.
250                                          The enigma of the varicocele, although a source of frustrati
251 entification of WFBV in part may resolve the enigma of these mass mortality events, the details of th
252  iTregs do not, our results suggest that the enigma of variable responses of different human diseases
253 N reentry, remain one of the most intriguing enigmas of cardiac electrophysiology.
254 ng to local functionality remains one of the enigmas of condensed matter physics.
255                                          The enigmas of rangeomorph morphology, evolution, and extinc
256               Epstein-Barr virus (EBV) is an enigma; on one hand, it infects and persists in latent f
257                The genus Neolecta defines an enigma: phylogenetically placed in a related group conta
258 he latter to escape the profound theological enigmas posed by notions of ID.
259           In Caenorhabditis elegans, the ALP-Enigma protein family is encoded by a single gene, alp-1
260  proteins from the Zyxin, Paxillin, Tes, and Enigma proteins accumulate to SFSS.
261 ations that affect the Z-disk-associated ALP-Enigma proteins have been linked to human muscular and c
262 human health, the mechanism of action of ALP-Enigma proteins is largely unknown.
263 8 cohorts currently participating in the PGC-ENIGMA PTSD working group (a joint partnership between t
264 Neuroimaging Genetics through Meta-Analysis (ENIGMA) PTSD Working Group.
265  the yeast deletion library, we addressed an enigma regarding the apparent prevalence of gene dispens
266               These findings may explain the enigma regarding why COX-2 inhibitors are palliative rat
267 function relationships in uPAR, one puzzling enigma remains unexplored.
268                                   This first ENIGMA Schizophrenia Working Group study validates that
269                                Recently, the ENIGMA-Schizophrenia DTI Working Group performed a large
270 q11DS-psychosis to idiopathic schizophrenia (ENIGMA-Schizophrenia Working Group) revealed significant
271 ted circulating progesterone has remained an enigma since Csapo first theorized of a functional withd
272 otrophic lateral sclerosis (ALS) has been an enigma since its description by Charcot in 1869.
273 ely used, this model has remained in part an enigma since mice that carry the Tg.AC transgene (consis
274 placental mammals have remained a scientific enigma since the discovery of MHC haplotype diversity an
275  retinitis pigmentosa presents a fascinating enigma: some mutation carriers are blind, while others a
276 essed by 32 international laboratories using ENIGMA standardized procedures.
277                                              Enigma subfamily proteins (Enigma, Enigma homolog protei
278                                    Among the Enigma subfamily, Cypher has been demonstrated to play a
279        These biochemical findings lead to an enigma that how PTPN11 mutations with opposite effects o
280 aining fundamental questions surrounding the enigma that is BV.
281                      Either conclusion is an enigma that points to gaps in our fundamental understand
282 rting point for explaining the long standing enigma that the E2b core of the BCKDC binds E3 far more
283                               It has been an enigma that Treg exhibit an anergic phenotype reflected
284 plicated by the early presence of an African enigma, the bottle gourd (Lagenaria siceraria).
285 lth used a novel approach to disentangle the enigma: The 116 cases of scarlet fever were compared wit
286 ession of the other has been a long-standing enigma, though we know RUNX transcription factors activa
287                        Explanations for this enigma typically invoke the deposition in the corona of
288                                              ENIGMA-Viewer is an open-source tool, the source code an
289                                              ENIGMA-Viewer supports presentations and communications
290                                   We present ENIGMA-Viewer, an interactive web-based visualization to
291                                One remaining enigma was the basis for depolarization-induced weakness
292                     In order to resolve this enigma, we have calculated the free energy landscape of
293                              To unravel this enigma, we investigated transactivation response RNA bin
294 anoma, eumelanin photoprotection is still an enigma: What makes this pigment so efficient in dissipat
295                               It has been an enigma whether the hormone interacts with the endodomain
296                          It has long been an enigma whether the mechanism of P(4)-ATPases resembles t
297  up or slowed down during the observation of Enigma while we simultaneously recorded their eye moveme
298 sis, we used the data from the international ENIGMA Working Group collaboration, which in the present
299                                    Myc is an enigma wrapped in a mystery.
300 e even at large particle size, presenting an enigma yet to be understood.

 
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