ライフサイエンスコーパス: ensheath

1 on channels on the surface of the axons they ensheath.

2 between the oligodendrocyte and the axons it ensheaths.

3 d that only about 20-30% of each synapse was ensheathed.

4 Moreover, FRCs produce and ensheath a network of extracellular matrix (ECM) microfi

5 ing oligodendrocytes are generated and axons ensheathed according to a tightly regulated sequence of

6 ine glia (MG) are multifunctional cells that ensheath and provide trophic support to commissural axon

7 from NRG1 type III deficient mice are poorly ensheathed and fail to myelinate; lentiviral-mediated ex

8 y parameters, such as the number of synapses ensheathed and the strength of this ensheathment, we sho

9 al muscle is produced by the muscle cells it ensheathes and by nonmuscle cells located in the surroun

10 In contrast, the widespread ensheathing and astrocyte-like glia derive from specific

11 tex where neuronal cell bodies reside, while ensheathing and astrocyte-like glia enwrap and infiltrat

12 proteins, erbB2 and erbB3, are expressed on ensheathing and myelinating Schwann cells and rapidly ph

13 Myelin, which ensheaths and insulates axons, is a specialized membrane

14 specialized, proteolipid-rich membrane that ensheaths and insulates nerve fibers, facilitates the ra

15 disproportionately unmyelinated, aberrantly ensheathed, and hypomyelinated, with reduced conduction

16 precursors, and that most adult perineurial, ensheathing, and astrocyte-like glia are produced after

17 ons, activated microglia closely apposed and ensheathed apical dendrites, neurites, and neuronal peri

18 do not tile: each astrocyte participates in ensheathing approximately one-quarter of all of the axon

19 tatus information via paracrine signals from ensheathing astrocytes.

20 o-express Lepr and interleukin-33 (Il33) and ensheath AT sympathetic axon bundles.

21 Only the AMG ensheath axon commissures, whereas the function of the n

22 d Na+ channels and ankyrinG form adjacent to ensheathed axonal segments even in the absence of a myel

23 Myelin is a multilayered membrane that ensheathes axonal fibers in the vertebrate nervous syste

24 This mutant has oligodendrocyte-ensheathed axons but lacks compact myelin and normal axo

25 In the coculture, myelin specifically ensheathed axons but not dendrites of hippocampal neuron

26 Ensheathed axons express low levels whereas myelinated f

27 Oligodendrocytes that ensheathed axons expressed and selectively targeted prot

28 as 3 months after injury and their processes ensheathed axons near and distal to the lesion, colocali

29 Mutant oligodendrocytes also ensheathed axons normally and made a few wraps of compac

30 t propagation of action potentials along the ensheathed axons.

31 ematic occurrence has remained undetected in ensheathed axons.

32 yelin in layer 2/3 and a quarter in layer 4) ensheathes axons of inhibitory neurons, specifically of

33 Myelin ensheathes axons to allow rapid propagation of action po

34 hat OPCs were more capable of contacting and ensheathing axons than OLs.

35 tebrate midline glia play important roles in ensheathing axons that cross the midline and secreting s

36 o mature oligodendrocytes and are capable of ensheathing axons with myelin without molecular cues fro

37 Glia play crucial roles in ensheathing axons, a process that requires an intricate

38 tion of the oligodendrocyte plasma membrane, ensheaths axons to facilitate electrical conduction.

39 Myelin membrane, which ensheaths axons, has an unusually high amount of cholest

40 a present on CSF-facing leptomeningeal cells ensheathing blood vessels in the subarachnoid space may

41 olecules that underlies epithelial cells and ensheaths blood vessels.

42 elaborate membrane extensions that partially ensheathed both commissures.

43 t regenerated into grafts, and appropriately ensheathed but did not myelinate sensory axons extending

44 Furthermore, axoplasm ensheathed by 65% of the CNS incisures examined by elect

45 of numerous short and swollen lateral roots ensheathed by a fungal mantle.

46 The Drosophila nervous system is ensheathed by a layer of outer glial cells, the perineur

47 elop the adult neuroblast and are themselves ensheathed by a layer of processes of multipolar cell bo

48 Along their route, neuroblasts are ensheathed by astrocyte-like cells expressing vesicular

49 a network of chains of migrating neuroblasts ensheathed by astrocytes and juxtaposed by clusters of i

50 the adult, migrating SVZa-derived cells are ensheathed by astrocytes, although the function of these

51 longated aggregates called chains, which are ensheathed by astrocytes.

52 these neuronal precursors migrate in chains, ensheathed by astrocytic processes, and travel toward th

53 t only those maturing blood vessels that are ensheathed by astroglial processes.

54 litated by fiber bundles, particularly those ensheathed by fibroblastic reticular cells in the lymph

55 cular network, a meshwork of collagen fibers ensheathed by fibroblastic reticular cells that connects

56 peripheral nerves are unmyelinated but still ensheathed by glia.

57 show that individual or a group of axons are ensheathed by inner glial processes, which in turn are e

58 Axons in the PNS and CNS are ensheathed by multiple layers of tightly compacted myeli

59 tial proportion of these APP+ spheroids were ensheathed by myelin, a finding that was confirmed in th

60 propagation of action potentials, axons are ensheathed by myelin, a multilayered insulating membrane

61 e primary heart tube is an endocardial tube, ensheathed by myocardial cells, that develops from bilat

62 and ankyrinG are adjacent to axonal segments ensheathed by oligodendrocytes, but at P21, many node-li

63 Axons ensheathed by oligodendroglial processes, but not yet my

64 he abluminal surfaces of CNS capillaries are ensheathed by pericytes and astrocytes.

65 ive (-IR) neurons have also been shown to be ensheathed by perineuronal nets (PNN), extracellular mat

66 (+) neuronal glutamatergic synapses that are ensheathed by processes from individual developing astro

67 In the retina, RGCs are ensheathed by retinal Muller glial (RMG) cell processes.

68 ckout mice develop normally, become properly ensheathed by Schwann cells, and appear to function norm

69 The CNS is ensheathed by the meninges and cerebrospinal fluid, and

70 by inner glial processes, which in turn are ensheathed by the outer perineurial glial cells.

71 mum of an astrocytic process, but none were ensheathed by those processes.

72 peripheral nerve in the Drosophila larva is ensheathed by three glial layers, which structurally sup

73 Chains of Type A cells were ensheathed by two ultrastructurally distinct astrocytes

74 xpressed in Schwann cells and the axons they ensheath cause the hereditary motor and sensory neuropat

75 The olfactory ensheathing cell (OEC) has attracted much interest recen

76 spinal cord transection model and olfactory ensheathing cell (OEC) or fibroblast (FB; control) trans

77 the fact that the neuroprotective olfactory ensheathing cell (OEC) subset is difficult to isolate, m

78 Olfactory ensheathing cell (OEC) transplantation is a candidate ce

79 One beneficial therapy, olfactory ensheathing cell (OEC) transplantation, results in funct

80 lfactory receptor neuron (ORN) and olfactory ensheathing cell maturation; however, directed outgrowth

81 ork has implicated this pathway in olfactory ensheathing cell support for regeneration of axons from

82 Intraspinal olfactory ensheathing cell transplantation improves locomotor outc

83 ently discovered type of cell, the olfactory ensheathing cell, which can be obtained from the adult n

84 After SCI, ensheathing cells (ECs) promote recovery in animal model

85 eeze fracture, P faces of both the axons and ensheathing cells (glia that surround the axon fascicles

86 ne or in combination with cultured olfactory ensheathing cells (OEC) into the lesion cavity 6 weeks a

87 st that correct development of the olfactory ensheathing cells (OEC) is imperative for normal GnRH-1

88 lantation of a mixture of 50% p75+ olfactory ensheathing cells (OECs) and fibroblasts derived from th

89 Olfactory ensheathing cells (OECs) are candidate cells for transpl

90 Olfactory ensheathing cells (OECs) are known to enhance axonal reg

91 Olfactory ensheathing cells (OECs) are often described as being pr

92 Olfactory ensheathing cells (OECs) are specialized glia associated

93 Olfactory ensheathing cells (OECs) are the glia of the primary olf

94 Olfactory ensheathing cells (OECs) are unique glial cells found in

95 Transplants of olfactory ensheathing cells (OECs) cultured from the olfactory bul

96 ss Fz-1, Fz-3, and Wnt-5a, whereas olfactory ensheathing cells (OECs) express Wnt-4.

97 Olfactory ensheathing cells (OECs) have been reported to migrate l

98 Olfactory ensheathing cells (OECs) have been shown to mediate remy

99 Olfactory ensheathing cells (OECs) have considerable potential for

100 Olfactory ensheathing cells (OECs) have neuro-restorative properti

101 's gland cells, and GFAP(+)/p75(-) olfactory ensheathing cells (OECs) in the underlying lamina propri

102 allei infection, we infected human olfactory ensheathing cells (OECs) in vitro and measured bacterial

103 Transplantation of olfactory ensheathing cells (OECs) into injured spinal cord result

104 ere we describe transplantation of olfactory ensheathing cells (OECs) or Schwann cells derived from t

105 Olfactory ensheathing cells (OECs) or Schwann cells were transplan

106 Olfactory ensheathing cells (OECs) prepared from the olfactory bul

107 n of the calcium influx pathway in olfactory ensheathing cells (OECs) was performed using Indo-1 calc

108 actory sensory neurons (OSNs), and olfactory ensheathing cells (OECs), but was excluded from mature O

109 t rat Schwann cells (SCs), but not olfactory ensheathing cells (OECs), form a boundary with astrocyte

110 L a population of glial cells, the olfactory ensheathing cells (OECs), surround OSN axon fascicles.

111 for three-dimensional culturing of olfactory ensheathing cells (OECs), which can be used to understan

112 Olfactory ensheathing cells (OECs), which have properties of both

113 es include Schwann cells (SCs) and olfactory ensheathing cells (OECs).

114 n (GFP)-expressing donor rats [GFP-olfactory ensheathing cells (OECs)] into a region of spinal cord d

115 s and IL-6 from infiltrating macrophages and ensheathing cells act as repair factors in the ON.

116 prove that the NC give rise to the olfactory ensheathing cells and subpopulations of GnRH-1 neurons,

117 Olfactory ensheathing cells are a type of glial cell which can be

118 on of expression of LIFR, IL-6, and IL-6R in ensheathing cells by 3 days post-OBX.

119 ovide evidence that these specialized vessel-ensheathing cells contribute to the S1P that promotes th

120 A suspension of ensheathing cells cultured from adult rat olfactory bulb

121 Here, we transplanted olfactory ensheathing cells from green fluorescent protein (GFP)-e

122 ared following transplants of pure olfactory ensheathing cells from neonatal animals and mixed olfact

123 The origin of GnRH-1 cells and olfactory ensheathing cells has been controversial.

124 cent discovery of the potential of olfactory ensheathing cells has proved a significant advance.

125 ss in a first application of human olfactory ensheathing cells in clinical brachial plexus injury wou

126 l nerve glia play roles similar to olfactory ensheathing cells in supporting axon elongation, yet dif

127 eronasal progenitors, formation of olfactory ensheathing cells in the nasal mucosa, and impairs GnRH-

128 erved in Gli3 mutants from lack of olfactory ensheathing cells in the nasal mucosa, moreover, we disc

129 ounding the olfactory epithelium (OE) and by ensheathing cells in the nerve layer of the ventral olfa

130 models transplantation of cultured olfactory ensheathing cells into an injured spinal cord induces re

131 a of olfactory mucosa and cultured olfactory ensheathing cells into the lesion cavity) 6 weeks after

132 Schwann cells are the nerve ensheathing cells of the peripheral nervous system.

133 ervations indicate that Sema3A expression by ensheathing cells plays an important role in guiding olf

134 Ensheathing cells remained restricted to the outer nerve

135 transplantation of cultured adult olfactory ensheathing cells restores the sensory input needed for

136 demonstrate that Schwann cells and olfactory ensheathing cells share a common developmental origin.

137 How perineurial glia, the ensheathing cells that form the protective blood-nerve b

138 ultures (containing a mean of ~50% olfactory ensheathing cells) in a population of spinal cord-injure

139 s, elevation of cyclic AMP levels, olfactory ensheathing cells, a steroid or chondroitinase.

140 they share features with mammalian olfactory ensheathing cells, the developmental roles of antennal n

141 roots and differentiate into nonmyelinating ensheathing cells.

142 that migrate inward and to the posterior to ensheath commissural axons, and PMG that migrate inward

143 Within lymph nodes, stromal cell-ensheathed conduit networks transport small antigens dee

144 Axons that failed to ensheath degenerated rapidly postnatally, specifically r

145 Chromosome ensheathing delays mitosis and increases the frequency o

146 In many instances, CARTir terminals ensheathed dendrites of SNr neurons.

147 ydrophobic pocket that adaptively expands to ensheath differing-length lipid chains using a cleft-lik

148 e most efficient mixtures were aggregates of ensheathed DNA and fused liposomes.

149 he F-Cell adopts a specialized morphology to ensheath each bristle.

150 ry endings accommodated in a lumen formed by ensheathing epithelia or glia.

151 tures-the choroid plexus vasculature and its ensheathing epithelium.

152 neocortical gray matter is thought to mostly ensheath excitatory axons connecting to subcortical regi

153 These arterioles are ensheathed exclusively by rare NG2 (also known as CSPG4)

154 ed can direct midline glia to a PMG-like non-ensheathing fate.

155 matic changes in cell shape and individually ensheath germ cells as the gonad coalesces.

156 ndicate that NG exchanges identities between ensheathing glia (EG) and astrocyte-like glia (ALG).

157 everal studies have suggested that olfactory ensheathing glia (EG) can form Schwann cell (SC)-like my

158 promoting properties of adult olfactory bulb ensheathing glia (EG).

159 Olfactory ensheathing glia (OEG) are distinct from other glia in t

160 promise are olfactory bulb-derived olfactory ensheathing glia (OEG) transplantation and treadmill ste

161 As olfactory ensheathing glia (OEG) transplantation improves hindlimb

162 n anatomical evidence suggest that olfactory ensheathing glia (OEG) transplantation promotes axon reg

163 d adult rat Schwann cells (SCs) or olfactory ensheathing glia (OEG), or both, were transplanted in th

164 ormal locomotion which is similarly shown by ensheathing glia ablated larvae.

165 ll types in the adult Drosophila brain, with ensheathing glia acting as phagocytes after axotomy, and

166 Together these results argue that ensheathing glia and astrocytes are preprogrammed cell t

167 s contain two different populations of glia: ensheathing glia and astrocytes.

168 We find that ensheathing glia are polarized with a basolateral plasma

169 actions between spinal motor axons and their ensheathing glia are vital for forming and maintaining f

170 lies, gut-induced metabolic reprogramming of ensheathing glia becomes constitutive in old flies owing

171 this, we found that blocking endocytosis in ensheathing glia blocked the induction of plasticity.

172 Ensheathing glia enwrap major structures in the adult br

173 glial functions, beginning with the role of ensheathing glia in preventing ephaptic coupling, axogli

174 bset of globose basal cells and by olfactory ensheathing glia in the normal mucosa; Hes5 label disapp

175 We find ensheathing glia infiltrate specific target synaptic glo

176 uction, we discover serotonin signaling from ensheathing glia is required for experience-dependent sy

177 When the fray cDNA is expressed in the ensheathing glia of fray mutants, normal nerve morpholog

178 olfaction through metabolic reprogramming of ensheathing glia of the antennal lobe.

179 Schwann cells (SCs), ensheathing glia of the peripheral nervous system, suppo

180 oteinase-1 (MMP-1), is induced in Drosophila ensheathing glia responding to severed axons.

181 The anterior midline glia (AMG) are ensheathing glia that migrate, surround and send process

182 henotype is associated with a failure of the ensheathing glia to correctly wrap peripheral axons.

183 tless FGF receptor acts cell-autonomously in ensheathing glia to regulate process extension so as to

184 ticularly from local interneurons, instructs ensheathing glia to wrap each glomerulus.

185 uired for this critical period plasticity as ensheathing glia upregulate Draper, invade the VM7 glome

186 e gonadotropin-releasing hormone neurons and ensheathing glia which are also resident in the mesenchy

187 y neurons, non-neuronal cells, and olfactory ensheathing glia, all made from embryonic Pax7+ cells.

188 (outer and inner surface glia, cortex glia, ensheathing glia, and astrocytes), which show within-cla

189 e intestine activates JAK-STAT signalling in ensheathing glia, inducing the expression of glial monoc

190 However, whether remaining peripheral ensheathing glia, such as perineurial glia, properly enc

191 Heavily stained cells, probably ensheathing glia, surrounded the nerve fascicles.

192 Axotomy elicits Ca(2+) signals in ensheathing glia, which activates regenerative neurons t

193 il is separated from neuronal cell bodies by ensheathing glia, which as we show using dye injection e

194 CDH3 and CDH11 are expressed by olfactory ensheathing glia, which surround OSN axons in the outer

195 nt compartments by membranous processes from ensheathing glia.

196 factor Nrf2 mostly in the astrocyte-like and ensheathing glia.

197 st, the posterior midline glia (PMG) are non-ensheathing glia.

198 B(Heavy)-spectrin mutant larvae affect ensheathing glial cell polarity with delocalized PIP(2)

199 Olfactory ensheathing glial cells (OEGs) interact with a wide repe

200 that are remarkably similar to those of axon-ensheathing glial cells in unmyelinated invertebrates.

201 Furthermore, specialized olfactory-ensheathing glial cells located in the nasal cavity were

202 ein-blocking antibodies, or olfactory nerves ensheathing glial cells transplanted into the acutely in

203 thelia, including migrating GnRH neurons and ensheathing glial precursors of the migrating mass (MM),

204 coaxial non-lip progenitors; contrastingly, ensheathing granule cells derive principally from LRL.

205 to hypomyelinated mice, iOPCs are capable of ensheathing host axons and generating compact myelin.

206 Here we show that such chromosomes become ensheathed in multiple layers of endomembranes.

207 ons counted, 18% also expressed CB, 31% were ensheathed in PNN, and 7% expressed both CB and PNN.

208 , whereas unmyelinated axons were aberrantly ensheathed in Remak bundles, with increased numbers of a

209 ten fibers travel up the sides of the column ensheathed in the margins of the epidermal cells.

210 myelinating Schwann cells and the axons they ensheath is mediated by cell adhesion molecules of the C

211 d in the cerebral cortex, pia mater, and pia-ensheathed leptomeningeal vessels in two GBCA-exposed hu

212 The primary non-motile cilium, a membrane-ensheathed, microtubule-bundled organelle, extends from

213 abeled BMDC become satellite cells: membrane-ensheathed mononucleate muscle stem cells.

214 ocytes more efficiently than fetal OPCs, and ensheathed more host axons per donor cell than fetal cel

215 Type I "glial-like" cells, with their ensheathing morphology, are mostly viewed as responsible

216 Cldn14, Adamtsl1 and Pmp2 and preferentially ensheathes motor axons.

217 e rise to mature oligodendrocytes that could ensheath multiple host axons when co-cultured with prima

218 in-1d is expressed along the axon and in the ensheathing myelin compartment.

219 on microscopy (EM) images of axons and their ensheathing myelin from both the central and peripheral

220 ingle axons, oligodendrocytes preferentially ensheathed neighboring axons.

221 ndrocytes that do differentiate, all fail to ensheath neurites.

222 aggregates of the extracellular matrix which ensheath neuronal cell bodies, primary dendrites and axo

223 y GABA transporter subtype GAT4 on processes ensheathing neuronal precursors that contain GABA.

224 e in the cytosolic matrix of astrocytes that ensheath neurons and blood vessels, whereas NR2A/B is co

225 SGCs tightly ensheath neurons of sensory ganglia and can regulate neu

226 sends paracrine signals to activate TRPA1 of ensheathed nociceptors to sustain mechanical allodynia.

227 They share the ensheathing of synapses and vasculature with astrocytic

228 The apparent re-ensheathing of the OS by the apical processes of the ret

229 y, vascular pattern, or SM cell and pericyte ensheathing of vessels in SM alpha-actin null mice.

230 injury-induced demyelination and appeared to ensheath or remyelinate host axons.

231 The signals that determine whether axons are ensheathed or myelinated by Schwann cells have long been

232 omeninges, subpial astrocytes and astrocytes ensheathing penetrating blood vessels at the ventral sur

233 Smooth muscle cells (SMCs) and ensheathing pericytes (EPs), also named as terminal vasc

234 Smooth muscle cells of arterioles and ensheathing pericytes of the arteriole-capillary transit

235 yte-like cells or B-cells, sends projections ensheathing pericytes on SVZ capillaries in young mice.

236 Vertebrate and invertebrate epidermal cells ensheath peripheral arbors of somatosensory neurons, inc

237 We show that Schwann cells, the cells that ensheath peripheral nerve axons, and which traditionally

238 e arrival of glial processes that eventually ensheath persistent branches.

239 commissures, whereas the function of the non-ensheathing PMG is unknown.

240 It is not known whether adult-born OLs ensheath previously unmyelinated axons or remodel existi

241 omponent of the perineuronal net matrix that ensheaths principal neurons in the MNTB and the large ca

242 avid C17.2 cell-host axon contacts, and the ensheathing properties of these cells are related to the

243 axonal regrowth, and then remyelinate or re-ensheath regenerated axons, thereby ensuring functional

244 ptors suggests that the extracellular matrix ensheathing RPE microvilli contains ligands for this int

245 se progression that is triggered within axon ensheathing Schwann cells and that can be ameliorated by

246 he potential contribution of peripheral axon ensheathing Schwann cells to ALS by constructing transge

247 remature formation of heminodes around early ensheathing Schwann cells, and altered nerve conduction

248 er in DRG satellite cells and nonmyelinating ensheathing Schwann cells.

249 epidermal cells establish close contacts and ensheath sensory neurites.

250 en localized to protoplasmic astrocytes that ensheath synapses and modulate neuronal activity in the

251 Although glial cells ensheath synapses throughout the nervous system, the fun

252 ment membranes (BMs) at their endfeet, which ensheath the cerebrovasculature.

253 However, they do not ensheath the commissural axons, and as a result, the gli

254 They then wrap around and ensheath the commissural axons.

255 gene that result in a failure of the SGPs to ensheath the GCs, leading to defects in GC development.

256 n order to specify longitudinal muscles that ensheath the gut.

257 enesis, SGPs send out cellular extensions to ensheath the individual GCs and promote their developmen

258 is selectively expressed by glial cells that ensheath the migratory neurons (expressing APPL), and th

259 ophila is established by surface glia, which ensheath the nerve cord and insulate it against the pota

260 iated cortex glia that extend processes that ensheath the neuroepithelium, suggesting that glia cells

261 ral nervous system by the support cells that ensheath the neuronal sensory process.

262 Neuropile glia ensheath the neuropile and form septa within the neuropi

263 expressed primarily by the glial cells that ensheath the peripheral nerves.

264 ndle, indicating that Sema5A normally helped ensheath the retinal pathway.

265 oglia ceases as astrocyte endfeet more fully ensheath the vasculature.

266 h contained glial fibrillary acidic protein, ensheathed the chains of migrating neuroblasts.

267 we found that oligodendrocytes repetitively ensheathed the same axons multiple times before any stab

268 The glia limitans ensheathes the entire central nervous system (CNS) paren

269 The C. elegans AMsh glial cell ensheathes the NREs of 12 neurons, including the thermos

270 ious literature, our data suggest that cells ensheathing the dorsal aorta emerge from a sub-populatio

271 and seemed to be associated with glial cells ensheathing the peripheral nerves.

272 Unlike the basal lamina ensheathing the pharynx and body wall muscle, nidogen re

273 ous to the transporters in the Bergmann glia ensheathing the Purkinje cells), nor did it block the cu

274 olysis of caged Ca(2+) in astrocytic endfeet ensheathing the vessel wall was associated with an 18% i

275 While surface glia ensheaths the brain and is involved in the formation of

276 r cellular structure, the perineurium, which ensheaths the motor nerve, forming a flexible, protectiv

277 d in cells of the fibrous perichondrium that ensheaths the skeleton.

278 yces together provide a sleeve of axons that ensheaths the two shafts.

279 cells sort individual axons from bundles and ensheath them to generate multiple layers of myelin.

280 crete components of the basement membrane to ensheath them.

281 the Schwann cells and perineurial glia that ensheath them.

282 7.5), KCNQ4 is also found at calyx terminals ensheathing type I vestibular hair cells where it may be

283 sponded to when astrocyte endfeet more fully ensheath vessels.

284 Also, individual photoreceptor terminals are ensheathed within the outer plexiform layer (OPL) by the