ライフサイエンスコーパス: enterovirus

1 aviruses 229E, NL63, and OC43 and rhinovirus/enterovirus.

2 lity following infection with a common human enterovirus.

3 ditional non-EV-A71, non-CV-A16 serotypes of enterovirus.

4 dynamics caused by the multiple serotypes of enterovirus.

5 itis or encephalitis who tested positive for enterovirus.

6 replication of poliovirus, a representative enterovirus.

7 embling the uncoating intermediates of other enteroviruses.

8 a reemerging illness caused by a variety of enteroviruses.

9 requently the site of receptor attachment in enteroviruses.

10 FMD) is a common childhood illness caused by enteroviruses.

11 al [CI], 52%-63%) had infectious causes, 10% enterovirus, 10% parechovirus, 8% bacterial meningoencep

12 d respiratory viruses followed by rhinovirus/enterovirus (13%), influenza virus (12%), coronavirus (9

13 rystal structures of the picornavirus bovine enterovirus 2 (BEV2) and the cytoplasmic polyhedrosis vi

14 The results demonstrate that the enterovirus 2A protease directly cleaves the nuclear por

15 Unlike other enterovirus 3A proteins, HRV 3A failed to bind GBF1.

16 mon viruses detected by BFPP were rhinovirus/enterovirus (4.5%), influenza A virus (3%), and respirat

17 o differentially mediates the replication of enterovirus 68 and rhinovirus 16.

18 ion is also important for the replication of enterovirus 68 but disadvantageous to human rhinovirus 1

19 immunodeficiency virus 1, hepatitis C virus, enterovirus 70, and variant Creutzfeldt-Jakob disease.

20 Moreover, dominant virus types enterovirus 71 (EV-71) and coxsackievirus A16 (CV-A16) m

21 A related virus, enterovirus 71 (EV-A71), causes similar clinical outcome

22 Infection of enterovirus 71 (EV71) and associated hand, foot, and mou

23 Enterovirus 71 (EV71) can cause hand-foot-and-mouth dise

24 Enterovirus 71 (EV71) causes a spectrum of neurological

25 Enterovirus 71 (EV71) is a common cause of hand, foot an

26 Enterovirus 71 (EV71) is a human pathogen that causes ha

27 Enterovirus 71 (EV71) is a major public health threat th

28 Enterovirus 71 (EV71) is an emerging pathogen causing ha

29 Enterovirus 71 (EV71) is one of the primary causative ag

30 Enterovirus 71 (EV71) is responsible for most of the sev

31 Enterovirus 71 (EV71) is responsible for seasonal outbre

32 Enterovirus 71 (EV71) poses serious threats to human hea

33 Like other enteroviruses, enterovirus 71 (EV71) relies on phosphatidylinositol 4-k

34 NCE We report here that a stable full-length enterovirus 71 (EV71) reporter construct was used to vis

35 In the present study, we found that enterovirus 71 (EV71) RNA undergoes m6A modification dur

36 eous nuclear ribonucleoprotein A1 stimulates enterovirus 71 (EV71) translation in part through specif

37 on and rapid quantification method for human enterovirus 71 (EV71) using a portable surface plasmon r

38 ovirus 11 (E11), coxsackievirus B (CVB), and enterovirus 71 (EV71), and that contrary to an immortali

39 coxsackievirus B (CVB), poliovirus (PV), and enterovirus 71 (EV71), co-opt the host cell secretory pa

40 The main causative agents are enterovirus 71 (EV71), coxsackievirus A16 (CVA16), and,

41 reveal host-pathogen interactions.IMPORTANCE Enterovirus 71 (EV71), one of the major pathogens of hum

42 es titers against coxsackievirus A16 (CA16), enterovirus 71 (EV71), PV I-III and HIV-1 were performed

43 iverse roles in the efficient replication of enterovirus 71 (EV71), which is the causative agent of h

44 Enterovirus 71 (EV71)-neutralizing antibodies correlate

45 Enterovirus 71 may cause serious neurological disease in

46 We show that the 3A protein of enterovirus 71 recruits an enzyme, phosphatidylinositol

47 es are available only against poliovirus and enterovirus 71, and specific anti-enterovirus therapeuti

48 g HIV, hepatitis C virus, hepatitis B virus, enterovirus 71, influenza virus, respiratory syncytial v

49 I4KB to the RNA replication sites.IMPORTANCE Enterovirus 71, like other human enteroviruses, replicat

50 and emerging pathogens, such as poliovirus, enteroviruses 71 and D68, and others.

51 A71 (EV-A71) is an emerging pathogen in the Enterovirus A species group.

52 childhood illness caused by serotypes of the Enterovirus A species in the genus Enterovirus of the Pi

53 redominant human enterovirus species, namely Enterovirus A, B and C.

54 etween 2008 and 2013, with the two serotypes Enterovirus A71 (EV-A71) and Coxsackievirus A16 (CV-A16)

55 Enterovirus A71 (EV-A71) has been noted for its tendency

56 Enterovirus A71 (EV-A71) is an emerging pathogen in the

57 Enterovirus A71 (EV-A71) is the major cause of severe ha

58 ren's Hospital Colorado noted an outbreak of enterovirus A71 (EV-A71) neurological disease.

59 nd, foot and mouth disease (HFMD), caused by enterovirus A71 (EV-A71), presents mild to severe diseas

60 wed circulation of newly emerging strains of enterovirus A71 and enterovirus D68.

61 We analysed all enterovirus A71 complete genomes with collection dates f

62 Enterovirus, adenovirus A, Salmonella spp., Campylobacte

63 sing age and infection with RSV, rhinovirus, enterovirus, adenovirus, and bocavirus.

64 nant ToV-PLP protein derived from this novel enterovirus also showed strong deubiquitination and deIS

65 21.3% had a virus detected (56.4% rhinovirus/enterovirus and 30.7% influenza/parainfluenza/respirator

66 human enteric viruses (norovirus GI and II, enterovirus and group A rotavirus) and supplementary hyd

67 Enterovirus and human herpesvirus type 6 had agreements

68 buvirus is intermediate between those of the enteroviruses and cardioviruses, with a shallow, narrow

69 the ability of 3C(pro) proteins from diverse enteroviruses and coxsackieviruses to interfere with typ

70 of receptor engagement among ICAM-1-binding enteroviruses and rhinoviruses.

71 of influenza, the parainfluenza virus, some enteroviruses and the bacterium that causes tularaemia(3

72 ococcus pneumoniae; 1 HSV; 1 parechovirus; 1 enterovirus) and 2 with no cause identified.

73 erovirus type (in 1556 [13%] of 11 559 typed enteroviruses), and 292 (65%) of 448 patients with coxsa

74 ype, representing 1412 (12%) of 11 559 typed enteroviruses, and 384 (82%) of 467 individuals with ech

75 nd BK polyomaviruses, Aichi virus 1 (AiV-1), enteroviruses, and noroviruses of genogroups I, II, and

76 type for human pathogenic positive-sense RNA enteroviruses, and picornaviruses in general, transport

77 ce when considering the replication of human enteroviruses, and we believe that these data are unatta

78 Enteroviruses are a major cause of human disease.

79 e resilience of viral replication.IMPORTANCE Enteroviruses are a vast group of viruses associated wit

80 Enteroviruses are among the most common viral infectious

81 Group B enteroviruses are common causes of acute myocarditis, wh

82 w that the replication compartments (RCs) of enteroviruses are created through novel membrane contact

83 for potential antiviral therapies.IMPORTANCE Enteroviruses are significant human pathogens that can c

84 Recently, we discovered not only that enteroviruses are transmitted via vesicles as population

85 Enteroviruses are well known for their ability to cause

86 terovirus isolation (poliovirus and nonpolio enteroviruses) as an indicator of surveillance sensitivi

87 ed: 25 with acute flaccid myelitis, two with enterovirus-associated encephalitis, five with enterovir

88 us B rather than independent, short-duration enterovirus B infections may be involved in the developm

89 Major enterovirus B populations characterized by 5' terminal g

90 This study showed that prolonged enterovirus B rather than independent, short-duration en

91 Here, we show that in contrast to enteroviruses, BPIFB3 functions as a positive regulator

92 Enteroviruses can cause severe infections, especially in

93 Certain enteroviruses can infect beta cells in vitro(5), have be

94 It is still uncertain which viruses (besides enteroviruses) cause direct tissue damage, act as trigge

95 f EV71 and suggested EV71 as the most common enterovirus causing HFMD in Shawo.

96 ong-term clinical course of patients with an enterovirus central nervous system infection (ECI) is po

97 , this study is the largest investigation of enterovirus circulation in EU and EEA countries and conf

98 oV-PLP from a recombination event.IMPORTANCE Enteroviruses comprise a highly diversified group of vir

99 Enteroviruses comprise a large group of mammalian pathog

100 The group of enteroviruses contains many important pathogens for huma

101 y novel predictive markers for the course of enterovirus (CVB3) cardiomyopathy by screening for nonco

102 has been found to accelerate the loss of an enterovirus (CVB3/28) infectious titer, with little effe

103 simplex viruses 1 and 2, Epstein-Barr virus, enterovirus, cytomegalovirus, and chikungunya virus).

104 s, poliovirus, foot-and-mouth disease virus, enterovirus D-68, and a wide range of other human and no

105 ncluded bunyavirus, human herpesvirus 7, and enterovirus D-68, ultimately impacting care in two cases

106 Coxsackievirus A16 (CV-A16), CV-A6, and enterovirus D68 (EV-D68) belong to the Picornaviridae fa

107 Enterovirus D68 (EV-D68) caused a widespread outbreak of

108 Enterovirus D68 (EV-D68) has been infrequently reported

109 Enterovirus D68 (EV-D68) infection has been associated w

110 f severe respiratory illness associated with enterovirus D68 (EV-D68) infection was reported in mid-A

111 States experienced a nationwide outbreak of Enterovirus D68 (EV-D68) infection.

112 model, or the iPSC motor neurons.IMPORTANCE Enterovirus D68 (EV-D68) infections are on the rise worl

113 tes experienced an unprecedented outbreak of enterovirus D68 (EV-D68) infections.

114 Human enterovirus D68 (EV-D68) is a causative agent of childho

115 Enterovirus D68 (EV-D68) is a member of Picornaviridae a

116 Enterovirus D68 (EV-D68) is a member of the Picornavirid

117 Enterovirus D68 (EV-D68) is a viral pathogen that leads

118 Enterovirus D68 (EV-D68) is an atypical nonpolio enterov

119 Enterovirus D68 (EV-D68) is an emerging pathogen that ca

120 Enterovirus D68 (EV-D68) is an emerging virus that has b

121 During the enterovirus D68 (EV-D68) outbreak of 2014, the BioFire F

122 by employing a dual glycan receptor-binding enterovirus D68 (EV-D68) strain.

123 Enterovirus D68 (EV-D68) undergoes structural transforma

124 udy period with these findings in those with enterovirus D68 (EV-D68)-associated acute flaccid myelit

125 Enterovirus D68 (EV-D68)-associated acute flaccid myelit

126 ates, coincident with a national outbreak of enterovirus D68 (EV-D68)-associated severe respiratory i

127 mouse parainfluenza (Sendai) virus and human enterovirus D68 (EV-D68).

128 strengthen the putative association between enterovirus D68 and acute flaccid myelitis and the conte

129 st the possibility of an association between enterovirus D68 and neurological disease in children.

130 plausibility support an association between enterovirus D68 and the recent increase in acute flaccid

131 a rare yet severe clinical manifestation of enterovirus D68 infection in susceptible hosts.

132 V), coxsackievirus B3 (CVB3), poliovirus and enterovirus D68 infection, and chemical inhibitors of TN

133 Phylogenetic analysis revealed that all enterovirus D68 sequences associated with acute flaccid

134 tory illness were both infected by identical enterovirus D68 strains.

135 with acute flaccid myelitis but negative for enterovirus D68 using the two-tailed Fisher's exact test

136 Enterovirus D68 was detected in respiratory secretions f

137 acute flaccid myelitis who were positive for enterovirus D68 with those with acute flaccid myelitis b

138 of additional infections with Mayaro virus, enterovirus D68, and coronavirus NL63.

139 ewly emerging strains of enterovirus A71 and enterovirus D68.

140 nd temporally associated with an outbreak of enterovirus-D68 respiratory disease.

141 terovirus-associated encephalitis, five with enterovirus-D68-associated upper respiratory illness, an

142 We collected and analysed available enterovirus data across EU and EEA countries to assess t

143 s and confirms the availability of non-polio enterovirus data in the region.

144 he specificity of encapsidation of C-cluster enteroviruses depends on an interaction between capsid p

145 esponse than did persistent infections, with enterovirus detected at both time points (seroconversion

146 Aggregated data on any enterovirus detected between Jan 1, 2015, and Dec 31, 20

147 s, acute flaccid myelitis, and seizures) and enterovirus detected from any biological specimen were e

148 d solids, and higher pH were associated with enterovirus detection.

149 h neurological disease associated with other enteroviruses during the same period.

150 for the neonatal Fc receptor complexed with enterovirus E6 but is larger and distinct from that of a

151 In this study, a novel enterovirus (enterovirus species G [EVG]) (EVG 08/NC_USA

152 Like other enteroviruses, enterovirus 71 (EV71) relies on phosphati

153 Enterovirus (EV) and parechovirus (PeV) are leading vira

154 is a great need for antiviral drugs to treat enterovirus (EV) and rhinovirus (RV) infections, which c

155 Extensive research has identified enterovirus (EV) infections as key environmental trigger

156 eously as CFTR correctors and broad-spectrum enterovirus (EV) inhibitors.

157 f rhinovirus C (RV-C), a recently identified Enterovirus (EV) species, are the causative agents of se

158 The situation is even worse for enterovirus EV71 infection for which no antiviral therap

159 Epidemiologic evidence suggests non-polio enteroviruses (EVs) are a potential etiology, yet EV RNA

160 Enteroviruses (EVs) are among the most frequent infectio

161 Enteroviruses (EVs) are implicated in a wide range of di

162 Enteroviruses (EVs) are prime candidate environmental tr

163 ons in the capsids of rhinoviruses (RVs) and enteroviruses (EVs) by binding to a hydrophobic pocket i

164 Enteroviruses (EVs) causing persisting infection are cha

165 Enteroviruses (EVs) comprise a large genus of positive-s

166 ify the entire capsid coding region of human enteroviruses (EVs) including PV.

167 Rhinoviruses (RVs), respiratory enteroviruses (EVs), influenza virus, respiratory syncyt

168 To better understand how enteroviruses exert these effects on nuclear transport,

169 Positive rhinovirus/enterovirus FA targets revealed patterns loosely associa

170 Many members of the genus Enterovirus (family Picornaviridae) cause HFMD.

171 al case of cross-order recombination between enterovirus G (order Picornavirales) and torovirus (orde

172 LP functions as an innate immune antagonist; enterovirus G may therefore gain fitness through the acq

173 Here we report that many enterovirus genomes also harbour an upstream open readin

174 Several enterovirus genotypes and CRESS DNA genomes were associa

175 ; genus Hepatovirus) and some members of the Enterovirus genus, are released from cells nonlytically

176 ersistent viral forms are composed of B-type enteroviruses harboring a 5' terminal deletion in their

177 , Streptococcus agalactiae, cytomegalovirus, enterovirus, herpes simplex virus 1 and 2, human herpesv

178 %), HAdV (5.3%), Norwalk virus (6.6%), Human enterovirus (HEV) (9.2%), Human parechovirus (1.3%), Sap

179 Human rhinoviruses (HRVs), human enteroviruses (HEVs) and human parechoviruses (HPeVs) ha

180 2 (PLA2G16) was recently identified as a pan-enterovirus host factor and potential drug target.

181 has potential impact on understanding other enterovirus-host cell interactions.

182 nt are not conserved across SCARB2-dependent enteroviruses; however, a conserved proline and glycine

183 Based on reports showing the presence of enterovirus in atherosclerotic plaques we hypothesized t

184 piratory panel was used to detect rhinovirus/enterovirus in respiratory specimens; suspected EV-D68-p

185 lowed the identification of polioviruses and enteroviruses in artificial mixtures and was able to dis

186 miological features of HFMD and infection by enteroviruses in China.

187 highlights the wide circulation of non-polio enteroviruses in Europe, mostly affecting young children

188 y indicate the presence and density of these enteroviruses in the population and prolonged virus circ

189 n different cellular environments.IMPORTANCE Enteroviruses include many known and emerging pathogens,

190 Despite this barrier, enteroviruses, including coxsackievirus B3 (CVB3), succe

191 ids were susceptible to infection by diverse enteroviruses, including echovirus 11 (E11), coxsackievi

192 ramework for a system-level understanding of enterovirus-induced perturbations at the protein and sig

193 e formation, suggesting a mechanism by which enterovirus infect cells in atherosclerotic plaques.

194 ocrine cells are permissive, suggesting that enteroviruses infect specific cell populations in the hu

195 eveal a complex pattern of Arf activation in enterovirus-infected cells that may contribute to the re

196 future studies involving various degrees of enterovirus infection in mice, not just severe infection

197 Enterovirus infection induces the massive remodeling of

198 receptor (CXADR) genes, which can facilitate enterovirus infection(8).

199 he disease appears to be caused by non-polio enterovirus infection, posing a major public health chal

200 68 deaths were temporally associated with enterovirus infection.

201 igated the roles of small Arf GTPases during enterovirus infection.

202 t tag and investigated their behavior during enterovirus infection.

203 nalling as a major regulation network during enterovirus infection.

204 Enterovirus infections are associated with a number of s

205 Non-polio enterovirus infections are not notifiable in most countr

206 enomic RNA during viral infection.IMPORTANCE Enterovirus infections are responsible for human disease

207 Enterovirus infections can vary from asymptomatic infect

208 e than the bacterial microbiota, with recent enterovirus infections having a greater inhibitory effec

209 However, the events associated with enterovirus infections of the human gastrointestinal tra

210 together, our studies provide insights into enterovirus infections of the human intestine, which cou

211 teroids from human small intestines to study enterovirus infections of the intestinal epithelium.

212 9914 (66%) of 14 999 enterovirus infections with information about age were i

213 g data on morbidity and mortality related to enterovirus infections, as well as harmonising case defi

214 Recently acquired enterovirus infections, detected at vaccination but not

215 ications that occur in a small percentage of enterovirus infections.

216 pment of pharmacological inhibitors to treat enterovirus infections.

217 ells and may provide new ways of controlling enterovirus infections.

218 Although EV71, as well as other enteroviruses, initiates a remodeling of intracellular m

219 polyamine depletion but that a nonenveloped enterovirus is not.

220 The model enterovirus is poliovirus (PV), the causative agent of p

221 Viral infection with enteroviruses is a suspected trigger for T1D, but a caus

222 hows that while recombination with non-Sabin enteroviruses is associated with cVDPV, the recombinatio

223 ovirus-C (RV-C), a species of Picornaviridae Enterovirus, is strongly associated with childhood asthm

224 er coxsackieviruses, which are prototypes of enteroviruses, is dependent on an interaction of capsid

225 rests) to investigate their association with enterovirus isolation (poliovirus and nonpolio enterovir

226 is described frequently among non-rhinovirus enteroviruses, it seems to occur more rarely in rhinovir

227 Enterovirus, kobuvirus, parechovirus, parvovirus, and ro

228 Further, recombination with species C enteroviruses may indicate the presence and density of t

229 due to herpes simplex, varicella zoster, and enteroviruses) meningitis/encephalitis, neuroborreliosis

230 ing common samples containing poliovirus and enterovirus mixtures.

231 Enterovirus morphogenesis, which involves the encapsidat

232 cornaviridae peptides belonging to the genus Enterovirus (n = 29/42 cases versus 4/58 controls).

233 The most common targets detected were enterovirus (n = 38), human herpesvirus 6 (HHV-6) (n = 3

234 re best differentiated from those with other enteroviruses (n=31) by the neurological findings of myo

235 in 52 of 386 patients (13.4%); picornavirus (enteroviruses [n = 14], rhinovirus [n = 5], and parechov

236 ldren's Hospital Colorado were found to have enterovirus neurological disease; EV-A71 was identified

237 Nonpolio enterovirus (NPEV) serotypes were identified by means of

238 es of the Enterovirus A species in the genus Enterovirus of the Picornaviridae family.

239 cells/mm(3) would have missed an additional enterovirus, one cytomegalovirus (CMV), and two HHV-6 di

240 ortant implications for the understanding of enterovirus pathogenesis.

241 Enterovirus PCR of cerebrospinal fluid, blood, and recta

242 random forests model predicted "good" sites (enterovirus prevalence >70%) from measured site characte

243 were matched to 1345 samples with an average enterovirus prevalence among sites of 68% (range, 9%-100

244 hus, we have identified a previously unknown enterovirus protein that facilitates virus growth in gut

245 Enteroviruses proteolyze nuclear pore complex (NPC) prot

246 ride or peptidoglycan of bacterial origin to enterovirus provides thermal protection through stabiliz

247 is larger and distinct from that of another enterovirus receptor SCARB2.

248 lar PS lipids are co-factors to the relevant enterovirus receptors in mediating subsequent infectivit

249 te-Sabin isolate and Sabin isolate-non-Sabin enterovirus recombination after accounting for the time

250 ell paper, Laufman et al. (2019) reveal that enteroviruses recruit lipid droplets to support lipid sy

251 1, 2015, and Dec 31, 2017, through national enterovirus reference laboratories were requested from r

252 Network) inpatient study of 61 children with enterovirus-related neurological disease during a 2013 o

253 .IMPORTANCE Enterovirus 71, like other human enteroviruses, replicates its genome within host cells,

254 Moreover, it facilitates enterovirus replication and has been genetically linked

255 of BPIFB6 expression dramatically suppresses enterovirus replication in a pan-viral manner.

256 Enterovirus replication requires the cellular protein GB

257 These results reveal a mechanism of enterovirus replication that involves a selective strate

258 ins, GBF1, is a cellular factor required for enterovirus replication.

259 lipolysis pathway disrupts RC biogenesis and enterovirus replication.

260 de new insight into the molecular network of enterovirus replication.

261 et whose function could be targeted to alter enterovirus replication.

262 6 (BPIFB6), whose expression is required for enterovirus replication.

263 ulator of autophagy that negatively controls enterovirus replication.

264 rf1 appears to be the most important Arf for enterovirus replication.

265 ns as a positive regulator of CVB, and other enterovirus, replication by controlling secretory pathwa

266 rrected] for C. jejuni, Salmonella spp., and enteroviruses, respectively.

267 a virus 3, parainfluenza virus 4, rhinovirus/enterovirus, respiratory syncytial virus A and B, Bordet

268 r receptor of EV71, as well as several other enteroviruses responsible for hand, foot and mouth disea

269 uent infection with adenovirus, coronavirus, enterovirus/rhinovirus, and influenza virus (P = .062-.0

270 ruses (229E/OC43/NL63/HKU1/SARS/MERS), human enteroviruses/rhinoviruses, measles virus, mumps virus,

271 om 2014 to 2018 were examined for rhinovirus/enterovirus (RhV/EV) by the FilmArray respiratory panel.

272 sequencing, viral cDNA clones mimicking the enterovirus RNA sequences found in patient tissues were

273 These detailed studies establish enterovirus RNA structures as promising drug targets whi

274 Enterovirus RNA was more commonly identified in feces (4

275 sequences corresponding to the 5' termini of enterovirus RNAs were identified.

276 ed by month, age, sex, disease severity, and enterovirus serotype.

277 ple size or evaluation of detection for more enterovirus serotypes are not well investigated in Chong

278 ical community size (CCS) of HFMD associated enterovirus serotypes CV-A16 and EV-A71 and we explore w

279 edict future recombination events within the enterovirus species A group.

280 In this study, a novel enterovirus (enterovirus species G [EVG]) (EVG 08/NC_USA/2015) was is

281 rs of characteristic species groups, such as enterovirus species groups A to H or rhinovirus species

282 resentative members of the predominant human enterovirus species, namely Enterovirus A, B and C.

283 fectious poliovirus, providing insights into enterovirus species-specific protein-protein interaction

284 Enteroviruses support cell-to-cell viral transmission pr

285 ile and sterile site specimens, and enhanced enterovirus surveillance.

286 Together, we describe an enterovirus that can bypass PLA2G16 and identify additio

287 Coxsackievirus B (CVB) is a common enterovirus that can cause various systemic inflammatory

288 rovirus D68 (EV-D68) is an atypical nonpolio enterovirus that mainly infects the respiratory system o

289 ovirus and enterovirus 71, and specific anti-enterovirus therapeutics are lacking.

290 was done for C. jejuni, Salmonella spp., and enteroviruses to estimate risk of infection and illness.

291 kievirus A6 was the most frequently detected enterovirus type (in 1556 [13%] of 11 559 typed enterovi

292 s 30 was the second most frequently detected enterovirus type, representing 1412 (12%) of 11 559 type

293 Information collected included enterovirus types detected by month, patient age group,

294 ences for the three most clinically relevant enterovirus types, as identified from the data.

295 erscores the need for robust surveillance of enterovirus types, enabling improved understanding of vi

296 11 559 (67%) of 17 136 specimens revealed 66 enterovirus types.

297 findings overturn the 50-year-old dogma that enteroviruses use a single-polyprotein gene expression s

298 Enteroviruses use a type I Internal Ribosome Entry Site

299 ined for the presence of human rhinovirus or enterovirus using the FilmArray Respiratory Panel (RP) a

300 ns collected from children with EV-A71, this enterovirus was detected in 94% of rectal, 79% of oropha

301 Enteroviruses were the most frequently detected pathogen