ライフサイエンスコーパス: enzymatic reaction

1 ction as the initial step in a novel type of enzymatic reaction.

2 drolyzable analogs of ATP cannot support the enzymatic reaction.

3 ting the highly stereospecific nature of the enzymatic reaction.

4 induced by co-factor or product formed from enzymatic reaction.

5 rimetric signal (positive answer) through an enzymatic reaction.

6 functions as a general acid to initiate the enzymatic reaction.

7 bstrate and carbocation intermediates of the enzymatic reaction.

8 er and charged species generated by the same enzymatic reaction.

9 be established for the various steps of the enzymatic reaction.

10 ltiple ligands for cofactors crucial to this enzymatic reaction.

11 tert-butylhydroperoxide as substrate of the enzymatic reaction.

12 fast and presumably not rate-limiting in the enzymatic reaction.

13 antification of hydrogen fractionation in an enzymatic reaction.

14 a gradient in fluid density generated by the enzymatic reaction.

15 e is the partially rate-limiting step of the enzymatic reaction.

16 w oxamate exerts a stimulatory effect on the enzymatic reaction.

17 describe sequential steps in an induced fit enzymatic reaction.

18 xing and promote the specific starch-amylase enzymatic reaction.

19 w that bijels can be used as media to enable enzymatic reaction.

20 or recorded the voltage change caused by the enzymatic reaction.

21 , which in turn is produced by the preceding enzymatic reaction.

22 the decrease in oxygen level as a result of enzymatic reaction.

23 as short-lived intermediates in a number of enzymatic reactions.

24 roach is a powerful method for investigating enzymatic reactions.

25 for the hydroxylation of strong C-H bonds in enzymatic reactions.

26 s in quality such as endogenous chemical and enzymatic reactions.

27 assembly by connected, kinetically competing enzymatic reactions.

28 ay (SSP), which consists of three successive enzymatic reactions.

29 yotes, is produced through a series of eight enzymatic reactions.

30 The system consists of 16 metabolites and 23 enzymatic reactions.

31 e MBL-fold domain in supporting a variety of enzymatic reactions.

32 peptide bond formation, is among the slower enzymatic reactions.

33 (H(+)) can mediate metabolic process through enzymatic reactions.

34 ps us understand the chemical composition of enzymatic reactions.

35 tons binding to the (13)C over the course of enzymatic reactions.

36 ty of RNA and the limited range of available enzymatic reactions.

37 sses, as well as a crucial byproduct in many enzymatic reactions.

38 mption or production of NADH through cascade enzymatic reactions.

39 ns, cofactors, and metabolites necessary for enzymatic reactions.

40 used to establish the kinetic parameters of enzymatic reactions.

41 calculations of activation free energies of enzymatic reactions.

42 of various mammalian signaling pathways and enzymatic reactions.

43 ing is used to monitor the time evolution of enzymatic reactions.

44 cannot approach the exquisite selectivity of enzymatic reactions.

45 ins to perform complex sets of choreographed enzymatic reactions.

46 essential nutrient, involved in a variety of enzymatic reactions.

47 e of substrates and products from well-known enzymatic reactions.

48 free energy needed to catalyze a plethora of enzymatic reactions.

49 e vital insights into the mechanisms of such enzymatic reactions.

50 rotein motions in the reaction coordinate of enzymatic reactions.

51 ay and atomic movements remain open for many enzymatic reactions.

52 he mechanism of these biologically important enzymatic reactions.

53 n of DNA heteroduplexes without the need for enzymatic reactions.

54 rystal packing interactions on the course of enzymatic reactions.

55 ography offers a direct means for monitoring enzymatic reactions.

56 y and electronics of the transition state of enzymatic reactions.

57 that inhibit transcription, or other coupled enzymatic reactions.

58 such as transport, signaling, and control of enzymatic reactions.

59 rectly annotate proteins for 93% of analyzed enzymatic reactions.

60 e highly abundant in biology and critical in enzymatic reactions.

61 ble with redox-based colorimetric assays and enzymatic reactions.

62 are vital for metabolic processes and rapid enzymatic reactions.

63 ification of a sequence for nearly all known enzymatic reactions.

64 zation is essential for rate acceleration of enzymatic reactions.

65 strated for measuring products of in-droplet enzymatic reactions.

66 their sequence similarity, catalyze distinct enzymatic reactions.

67 y intermediates in atmospheric, organic, and enzymatic reactions.

68 ect quantification of the end product of the enzymatic reaction, 1-deoxy-D-xylulose 5-phosphate (DXP)

69 ction without of HRP, whereby is part of non-enzymatic reaction about 10% of the total reaction.

70 serves as a probe, perfectly fitting in the enzymatic reaction active site for probing the enzymatic

71 solvent transport, weak acid permeation, and enzymatic reactions adjacent to membranes.

72 sence of two different protein functions, an enzymatic reaction (alkaline phosphatase, ALP) and a lig

73 of scaffold and staple strands by RCA-based enzymatic reactions allows the generation of DNRs in one

74 sphate kinase Fab1 that performs the reverse enzymatic reaction also causes a lysosome expansion phen

75 the beta-hydroxybutyrate dehydrogenase (HBD) enzymatic reaction and by addressing the major challenge

76 g changes in the pH value due to an on-going enzymatic reaction and directly detect selectively the p

77 The concurrence of enzymatic reaction and ligand-receptor interactions is c

78 insight into how Rrp44 catalyzes a localized enzymatic reaction and performs an action distributed ov

79 These results confirm the important role of enzymatic reaction and self-assembly.

80 This method integrates enzymatic reactions and hydrazide chemistry to enrich O-

81 oduced from canonical metabolites by defined enzymatic reactions and may represent a large fraction o

82 o those applied in studies involving classic enzymatic reactions and Michaelis-Menten-type kinetic an

83 Enzymatic reactions and noncovalent (i.e., supramolecula

84 Enzymatic reactions and related protein conformational d

85 redox cycling of manganese or cobalt in the enzymatic reactions and suggest that structural and elec

86 dict the effect of intracellular crowding on enzymatic reactions and was herein applied to investigat

87 out the need for cDNA synthesis or any other enzymatic reactions and with a sensitivity of <10 pM tar

88 e use of aqueous microdroplets to accelerate enzymatic reactions and, in particular, to improve prote

89 ammable signal amplification without in situ enzymatic reactions, and intrinsic scalability to rapidl

90 ning metabolic labeling, click-chemistry and enzymatic reactions, and mass spectrometry-based proteom

91 omolar concentrations as a cofactor for ATP, enzymatic reactions, and other biological processes.

92 binding and dissociation, electron transfer, enzymatic reactions, and protein un- and refolding.

93 , dimensionality reduction, and irreversible enzymatic reactions are combined.

94 explore biomolecular assemblies and modulate enzymatic reactions are discussed.

95 Enzymatic reactions are highly efficient and specific of

96 As enzymatic reactions are influenced by many factors, a st

97 ral correlations between protein motions and enzymatic reactions are often interpreted as evidence fo

98 water (as a first-order approximation of the enzymatic reaction) are evaluated by an exhaustive quant

99 tradeoff between the speed and efficiency of enzymatic reactions, are naturally unveiled as a result.

100 s resulted in the description of three novel enzymatic reactions as follows: 1) oxidation of d-altrit

101 long-chain fatty acids, products of Them1's enzymatic reaction, as well as lysophosphatidylcholine (

102 lidate the method for analyzing steady-state enzymatic reactions associated with P(i) liberation in r

103 0 was significant for optimizing the forward enzymatic reaction at the expense of the reverse, thus e

104 O4/5'-OH ligase RtcB have a strong impact on enzymatic reactions at DNA 3'-OH ends.

105 ransfer of protons, generated by a series of enzymatic reactions, at an array of microinterfaces betw

106 he cell-wall cross-links are formed by a non-enzymatic reaction between a sulfonyl fluoride and an am

107 Radicals produced by the enzymatic reaction between acetylcholinesterase and hypo

108 An enzymatic reaction between o-phenylenediamine (OPD) and

109 mportant role that mediators may play in the enzymatic reactions between iodine and NOM.

110 roducts (AGEs) are formed in a series of non-enzymatic reactions between reducing sugars and the amin

111 esidues that have a direct involvement in an enzymatic reaction, but these so-called 'catalytic resid

112 s have recently been established for several enzymatic reactions, but they require periodic interrupt

113 Similarly, the inhibition of the enzymatic reaction by conduritol B epoxide and 1-deoxyno

114 synthesis from cholesterol commonly requires enzymatic reactions by 3beta-hydroxysteroid dehydrogenas

115 blies have been used to organize cascades of enzymatic reactions by controlling the relative distance

116 onitors and actively regulates pH-responsive enzymatic reactions by monitoring and controlling the fl

117 Herein, we show that an enzymatic reaction can generate peptide assemblies that

118 integrated micro-optics elements, continuous enzymatic reactions can be spectrophotometrically monito

119 The complex enzymatic reactions can now be studied one molecule at a

120 growing knowledge of how multicomponent non-enzymatic reactions can occur through inherently reactiv

121 through a stereo-specific hydroxylation, an enzymatic reaction catalyzed by the ectoine hydroxylase

122 bservations further the understanding of the enzymatic reaction catalyzed by TsaC, a threonylcarbamoy

123 The biosensor exploits three coupled enzymatic reactions catalyzed by AChE, choline oxidase a

124 tested solution causes an inhibition of the enzymatic reactions catalyzed by glucose oxidase and ure

125 avities that can serve as binding pockets or enzymatic reaction chambers.

126 Acting as a cascade of enzymatic reactions, complement is activated through the

127 ulate the conformation of an enzyme under an enzymatic reaction condition while monitoring the real-t

128 Subsequently, the critical enzymatic reaction conditions were established, and the

129 nt synthesis (ENS) refers to a process where enzymatic reactions control intermolecular noncovalent i

130 fold that modulate different steps along the enzymatic reaction coordinate.

131 Our findings shed new light on how enzymatic reactions could be affected by crowded conditi

132 Instead de novo enzymatic reactions could more productively benefit from

133 nes and Genomes (KEGG) 2011 (a comprehensive enzymatic-reaction database) that became nonorphan in KE

134 Direct (1)H NMR monitoring of the enzymatic reaction detected no accumulated reaction inte

135 zation (DESI) MS for the label-free study of enzymatic reactions directly from the bioassay matrix wi

136 c analysis demonstrated that the rate of key enzymatic reactions dropped by 75%.

137 ted to be powerful in dissecting the complex enzymatic reaction dynamics and related conformational d

138 ding the structure-function relationship and enzymatic reaction dynamics.

139 Enzymatic reactions, either by soluble enzymes or membra

140 In all enzymatic reactions enantiomerically enriched not natura

141 se to peroxide was determined after 5 min of enzymatic reaction following addition of standard substr

142 oped bio-nanogate was capable of controlling enzymatic reaction for AIV H5N1 sensing within 1h with a

143 ely respond to target molecules, and control enzymatic reaction for electrochemical measurements.

144 thesis that uses click chemistry rather than enzymatic reactions for the ligation of Illumina sequenc

145 The shell sequesters enzymatic reactions from the cytosol, analogous to the l

146 e sensing layer was composed of a sequential enzymatic reaction (glucose oxidase and peroxidase), whi

147 n Ab heteromultimer reveals nonspecific, non-enzymatic reactions (glycation), which are not detected

148 ) that enables luminescence signaling of the enzymatic reaction, greatly simplifying the measurement

149 As a byproduct of many enzymatic reactions, H2O2 is also a popular biosensor ta

150 between protein conformational dynamics and enzymatic reactions has been a fundamental focus in mode

151 y of transition state theory to the study of enzymatic reactions has been often challenged.

152 o-, site-, and stereoselectivity possible in enzymatic reactions has led to a surge in the developmen

153 None of these enzymatic reactions have been reported before.

154 analytical platform eliminates the need for enzymatic reactions, heat denaturation, and complicated

155 xample of monodomain hydrogels formed via an enzymatic reaction, illustrates a new biomimetic approac

156 NCCs were defined and for the first time the enzymatic reactions implied in chlorophyll degradations

157 ing) to find compounds inhibiting a specific enzymatic reaction in bacterial cells.

158 f the compounds produced and consumed on the enzymatic reaction in just one chromatographic analysis.

159 olesterol to pregnenolone, the rate-limiting enzymatic reaction in neurosteroidogenesis.

160 pling altered the free energy barrier of the enzymatic reaction in some cases.

161 nsferase domain of KATms that assists in the enzymatic reaction in the absence of a highly conserved

162 n to obtain, for example, Vmax and Km for an enzymatic reaction in the extracellular space of the tis

163 rogenic substrate that permits to follow the enzymatic reaction in the presence of each chromatograph

164 nsistently, the compounds inhibited the LpxA enzymatic reaction in vitro.

165 ess situations, in the form of a promiscuous enzymatic reaction in which the first enzyme of the poly

166 cohols or other acetyl-CoA derivatives using enzymatic reactions in a carbon-conserved and ATP-indepe

167 ibitors on the spatiotemporal propagation of enzymatic reactions in a confined environment in vitro.

168 Here, we review the latest studies of enzymatic reactions in biological condensates focusing o

169 nzymes and confirm the potential sequence of enzymatic reactions in biosynthesis.

170 Enzymatic reactions in complex environments often take p

171 ould be identified: (i) including additional enzymatic reactions in the glycosome, or (ii) adding a m

172 irs with high partial correlations represent enzymatic reactions in the known glycosylation pathway,

173 r which we develop a model that incorporates enzymatic reactions in the reaction terms.

174 ed proteins involved in 83% of all predicted enzymatic reactions in the tomato metabolic network.

175 abling monitoring of metabolism and specific enzymatic reactions in vivo.

176 ate levels of formaldehyde may be derived by enzymatic reactions including oxidative demethylation/de

177 necessary cosubstrate for numerous essential enzymatic reactions including protein and nucleotide met

178 g into different microstructures and various enzymatic reactions inducing volatile generation.

179 e carbon and hydrogen isotope effects of the enzymatic reactions initiating specific degradation path

180 Combining enzymatic reactions into multistep biocatalytic cascades

181 cess, converting cholesterol via a series of enzymatic reactions, into progesterone.

182 An enzymatic reaction involving target analyte and assay re

183 Enzymatic reactions involving redox processes are highly

184 On the basis of these results, other enzymatic reactions involving the change in membrane cha

185 chieved by parallel but distinct cascades of enzymatic reactions involving three enzymes: E1, E2, and

186 This enzymatic reaction is demonstrated herein both in vivo a

187 The enzymatic reaction is initiated by a nucleophilic activa

188 The enzymatic reaction is monitored by electrical impedance

189 ndalone without HRP immobilized, showing the enzymatic reaction is required in the process of hydroge

190 elieve that the role of the wing in the BirA enzymatic reaction is to orient the active site and ther

191 The enzymatic reaction is very efficient, and the reaction c

192 tion current of ferricyanide, product of the enzymatic reaction, is measured chronoamperometrically a

193 abolic flux, or exchange rates of endogenous enzymatic reactions, is now feasible in biological syste

194 Being a non-enzymatic reaction, it is a great challenge when it come

195 ytic and oxidative processes are utilized in enzymatic reactions leading to epigenetic modifications

196 formation stage was minor compared to other enzymatic reactions leading to NAD(+) synthesis.

197 A biosynthesis pathway have been identified, enzymatic reactions leading to the production of these c

198 te luminol was then added and after 5 min of enzymatic reaction, light emission signals (lambdamax=42

199 The presented assay shows that complex enzymatic reactions like an isothermal amplification can

200 attenuate BH4 biosynthesis and BH4-dependent enzymatic reactions, linking two major metabolic pathway

201 eparation, suggest new possibilities for how enzymatic reactions may be modulated within cells.

202 a suggest that intra-cellular scaffolding of enzymatic reactions may enhance the direct channeling of

203 study provided significant insight into the enzymatic reaction mechanism of AvLOx and presented a no

204 Based on the crystal structures, the enzymatic reaction mechanism of IMPases is accustomed to

205 being decisive for the nature of an observed enzymatic reaction mechanism.

206 ides as probes for (19)F NMR-based real-time enzymatic reaction monitoring is demonstrated with three

207 orming step and which are reconfigured in an enzymatic reaction network.

208 been invoked as intermediates in a number of enzymatic reactions, obtaining a detailed understanding

209 Enzymatic reactions occur in a crowded and confined envi

210 Our approach relies on the tandem enzymatic reaction of a fungal tyrosinase and the mammal

211 reathalyzer is exposed to ethanol vapor, the enzymatic reaction of ADH and ethanol transforms NAD(+)

212 have performed extensive simulations of the enzymatic reaction of both wild-type enzymes and several

213 ctivity towards o-quinone, a product of this enzymatic reaction of BPA oxidation catalyzed by tyrosin

214 The H2O2 generated during the enzymatic reaction of ChOx with cholesterol could be red

215 The enzymatic reaction of cytidine deaminase appears to be a

216 bout the membrane association and subsequent enzymatic reaction of PLA2.

217 n the P1 position, which catalyzes the first enzymatic reaction of the amplification loop of the alte

218 constant increments in the generated heat of enzymatic reaction of unstable and slowly degradable pep

219 scence property of the system resulting from enzymatic reaction of uricase and HRP (horseradish perox

220 this model, we monitored the uncatalyzed and enzymatic reactions of dithranol, a substrate for the no

221 partments (BMCs) that encapsulate sequential enzymatic reactions of diverse metabolic pathways.

222 ible loop can be involved in controlling the enzymatic reactions of hcSHMT and other enzymes.

223 , RLM enzymes take part in five out of eight enzymatic reactions of the Wood-Ljungdahl metabolic path

224 ng specific oligonucleotides that switch the enzymatic reaction on and off.

225 ngated glycans were accessible by performing enzymatic reactions on partially protected UV-absorbing

226 dy, we propose a novel kinetic mechanism for enzymatic reactions on protein scaffolds to explain thes

227 n investigated to some extent, its effect on enzymatic reactions operating at the water/lipid interfa

228 r purposely (e.g. during pathogen killing or enzymatic reactions) or accidentally (e.g. exposure to r

229 The synthesis of RA requires two enzymatic reactions: oxidation of retinol into retinalde

230 Biological processes require specific enzymatic reactions, paradoxically involving short recog

231 Enzymatic reactions, photophysically monitored in real t

232 and eukaryotes, where they carry out diverse enzymatic reactions, probably related to structural diff

233 of fresh enzyme leads to greatly accelerated enzymatic reaction processes without the need of externa

234 class-enzyme leads to a greatly accelerated enzymatic reaction processes without the need of externa

235 show here that phospholipase D (PLD) and its enzymatic reaction product, phosphatidic acid (PA), regu

236 bsorption bands of both antioxidants and the enzymatic reaction product/s show a strong overlap.

237 The environmentally friendly enzymatic reaction products, methylxanthines, are high-v

238 V relative to Y at pH 7.5) provide probes of enzymatic reactions proposed to involve Y.'s in catalysi

239 After the enzymatic reaction, quercetin is extracted with ethyl ac

240 measure of the temperature sensitivity of an enzymatic reaction rate or a physiological process due t

241 t also, in some cases, in facilitating their enzymatic reaction rates at favorable reaction condition

242 nd PLD2, two proteins that catalyze the same enzymatic reaction, regulate different steps in mast cel

243 This novel method with fewer enzymatic reactions results in a higher quality of the l

244 The enzymatic reaction retains the stereochemistry of the an

245 minimum number of process steps, whereas the enzymatic reaction solution was monitored by a smartphon

246 in all kingdoms of life and catalyze diverse enzymatic reactions such as mRNA capping, the cyclizatio

247 Enzymatic reactions, such as isomerisation, dehalogenati

248 The KIEs measured for the enzymatic reaction suggest a similar mechanism of cycliz

249 near-complete metabolic network with 98% of enzymatic reactions supported by annotation or experimen

250 An enzymatic reaction system was designed that allows for r

251 ns of cyclophilin A and its substrate as the enzymatic reaction takes place.

252 and respiratory chains involves a series of enzymatic reactions that are coupled through redox media

253 branes de novo through a complex sequence of enzymatic reactions that are difficult to reconstitute i

254 This review gives an overview of enzymatic reactions that have been conducted on substrat

255 Diffusion is less affected than the diverse enzymatic reactions that have distinct individual temper

256 Despite the myriad of selective enzymatic reactions that occur in water, chemists have r

257 construction of kinetic descriptions of the enzymatic reactions that occur within a cell.

258 NADH and NADPH undergo spontaneous and enzymatic reactions that produce R and S forms of NAD(P)

259 on of TAG can be limited by flux through the enzymatic reactions that supply DAG.

260 elis-Menten model describing the kinetics of enzymatic reactions, the role of redox mediators and the

261 (ATP) determination are based on cascades of enzymatic reactions; therefore, they are sensitive to gl

262 The transition of each enzymatic reaction to a micrometer sized labeled product

263 en rely on either a nanoparticle label or an enzymatic reaction to generate a signal that is easily d

264 with a hydroquinone mediator then allowed an enzymatic reaction to proceed, generating benzoquinone.

265 nsferred to a glucose solution to trigger an enzymatic reaction to produce gluconic acid, which ioniz

266 This model predicted anchored enzymatic reactions to be accelerated, amplified, and in

267 ify biochemiluminescence coupled biospecific enzymatic reactions to detect analytes in biological flu

268 Living cells compartmentalize materials and enzymatic reactions to increase metabolic efficiency.

269 omologous recombination requires coordinated enzymatic reactions to prepare it for interaction with i

270 ulates many essential processes ranging from enzymatic reactions to species migration.

271 previously, may be potentially important for enzymatic reactions/transactions on nucleosomal substrat

272 idin/biotin complex, antibody amplification, enzymatic reactions, triplex structure formation and cat

273 imitations inherent to the properties of the enzymatic reaction used to identify interactions and to

274 ntroduces a unique approach to investigating enzymatic reactions using KIEs.

275 ass lower than 3kDa reduced 89% of the HMGCR enzymatic reaction velocity.

276 The enzymatic reaction was able to cause significant current

277 The hydrogen peroxide generated by the enzymatic reaction was detected in an electrochemical fl

278 This enzymatic reaction was found to produce expected RS meth

279 -state equilibrium ratio of IPP/DMAPP in the enzymatic reactions was approximately 1:7.

280 To detect the enzymatic reaction, we employed a BDD electrode modified

281 The enzymatic reactions were accomplished within the tempera

282 Because all enzymatic reactions were optimized and driven to apparen

283 anges in the molecular layer, as a result of enzymatic reactions, were detected by electrochemical im

284 icient in enhancing the reaction velocity of enzymatic reactions, where proteins and filament ends ar

285 of the different species associated with the enzymatic reaction which, exempli gratia, give informati

286 The enzymatic reaction, which requires Mg(2+) cations, is ca

287 osaccharides (FOS) are currently obtained by enzymatic reaction with fructosyltransferases (FTFs) usi

288 e determination in blood serum samples after enzymatic reaction with glucose oxidase immobilized on m

289 nge in the fluorescence intensity during the enzymatic reaction with glucose.

290 optical biosensor was developed based on the enzymatic reaction with halogenated aliphatic hydrocarbo

291 The electrochemical response of the enzymatic reaction with o-phenilendiamine and H(2)O(2) a

292 Coupling enzymatic reactions with electrochemical regeneration of

293 Integrating chemical and enzymatic reactions with MS-based proteomics, the curren

294 form potent MAIT-activating antigens via non-enzymatic reactions with small molecules, such as glyoxa

295 e strength of signal amplification by immuno-enzymatic reactions with the superior detection characte

296 f Penicillium simplicissimum, and subsequent enzymatic reactions with these compounds generated two a

297 werful biphasic reaction media to accelerate enzymatic reactions with various hydrophobic reagents.

298 tively merges cells with reagents to achieve enzymatic reactions without having to physically isolate

299 rtant role for electrostatic interactions in enzymatic reactions, yet this hypothesis has proved vexi

300 The enzymatic reactions yielding these galactolipids have be