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1 s, aptamers can be synthesized chemically or enzymatically.
2 tes may be acetylated chemically rather than enzymatically.
3 t microorganisms can efficiently reduce them enzymatically.
4 to reactivate inactive dehydrocorticosterone enzymatically.
5 adduct is converted into the natural product enzymatically.
7 R1, R2, R4, and R7 VP1 polymerases could be enzymatically activated by genotype C1, C2, C4, C5, and
10 tx1 and Stx2 are AB5 toxins consisting of an enzymatically active A subunit associated with a pentame
13 analysis indicates that these E3 ligases are enzymatically active and ubiquitinate the ACR residues L
14 s injection of NAD(+) increased the level of enzymatically active ARTC2.2 in serum, indicating that t
15 gative eGFP-gephyrin(L2B) (a chimera that is enzymatically active but clustering defective), curtaile
16 roteasome-mediated degradation, and keeps it enzymatically active by blocking its deactivating phosph
17 in infected corneas had multiple specks with enzymatically active caspase-1 (YVAD-FLICA 660), and bon
18 acidic mammalian chitinase (AMCase) are the enzymatically active chitinases that have been implicate
20 and activated clotting factors assemble into enzymatically active complexes on the exposed lipid, ult
21 -like cycle was slower, and (c) MPO retained enzymatically active conformation after complexation wit
22 more restricted expression patterns that is enzymatically active despite a distinct electrostatic su
24 he flexible loop region connecting the bulky enzymatically active head and the four-helix bundle stal
25 restored by complementing the KO cells with enzymatically active human FAM173B or with a putative FA
26 at UPRT from all higher eukaryotes is likely enzymatically active in vivo and challenges the previous
27 on a second in-frame ATG codon to produce an enzymatically active isoform lacking this N-terminal dom
29 etic rescue experiments showed that only the enzymatically active KDM3B could recover the phenotype.
30 lyceridemia may be to increase the amount of enzymatically active LPL by preventing its inhibition by
31 and Masp1/3(-/-) mice, we found that lack of enzymatically active MASP-3, or complete MASP-3 deficien
32 ization and crystal cross-linking generating enzymatically active material that can be stored for mon
33 ed PMNs during TEM displayed a high level of enzymatically active matrix metalloproteinase 9 (MMP-9),
37 lymer filaments, cross-linking proteins, and enzymatically active motor proteins collectively self-or
40 out synovial fluid supernatants and detected enzymatically active neutrophil primary granule enzymes,
43 nces PSY protein stability and increases the enzymatically active proportion of PSY in clpc1, counter
44 MCase) and chitotriosidase-1 (CHIT1) are two enzymatically active proteins produced by mammals capabl
46 f AtOR significantly increased the amount of enzymatically active PSY, whereas an ator ator-like doub
51 ppears that after the initial cloning of the enzymatically active soluble part of P. aeruginosa AlgC
52 rm traps the pyruvate kinase tetramer in its enzymatically active state with the B-domain acting as a
55 rization and measure how the lifetime of the enzymatically active tetramer is affected by different d
57 ination (Cre) targeted into the procapsid is enzymatically active within the procapsid and recircular
59 sulin shell associates with iron, but is not enzymatically active, and we demonstrate that EncFtn mus
60 etry-directed design of an extremely stable, enzymatically active, hollow protein cage of M(r) ~ 2.1
61 (ECoV), and equine torovirus Berne (BEV) are enzymatically active, rescue replication of MHV(Mut) in
63 Although these sigma(S)-TIC crystals are enzymatically active, they are slow in nucleotide additi
72 active electrostatic interactions induced by enzymatically added charges, we demonstrate that phospho
74 of both DNA and protein with release of the enzymatically altered protein-DNA complexes from the nan
76 While the low abundance and inability to enzymatically amplify DNA damage are obstacles to genome
78 gical processes, is produced in mammals both enzymatically and by reduction of nitrite and nitrate io
81 ese self-terminated polyamide dendrimers are enzymatically and hydrolytically stable and also exhibit
82 ese data indicate that NanA contributes both enzymatically and nonenzymatically to pneumococcal patho
83 l tissues of third molar teeth were digested enzymatically and the proliferative potential of human P
84 our system is demonstrated by replacing the enzymatically biased RNA-to-DNA reverse transcription st
86 to label membrane proteins carrying a short, enzymatically biotinylated tag, compatible with SRI tech
89 ow G-quadruplex structures could be unfolded enzymatically came in the late 1990s with reports that s
90 lies is oligomerization, wherein a series of enzymatically catalysed reactions is employed to generat
91 sensors have been applied for monitoring an enzymatically catalyzed degradation of polymers for the
93 trite by nitrate-reducing microorganisms and enzymatically catalyzed, nitrate-dependent U(IV) oxidati
94 gh the reduction of 8-oxogeranial is clearly enzymatically catalyzed, the cyclization step appears to
95 ri-block nanoparticle (TBN) comprising of an enzymatically cleavable porous gelatin nanocore encapsul
96 PMA) copolymer-drug conjugates which contain enzymatically cleavable sequences (GFLG) in both polymer
98 s, amide linkage, redox-cleavable bonds, and enzymatically-cleavable bonds are also thoroughly descri
99 ottom-up proteomics workflow uses trypsin to enzymatically cleave proteins C-terminal to lysine and a
103 up and an amino acid ester moiety, which are enzymatically cleaved-off inside cells to release the fr
106 enable radical polymerization in solution by enzymatically consuming oxygen as it oxidizes glucose.
107 ed HSPC mobilization, demonstrating that the enzymatically controlled vascular gateway specifically o
108 luminescence being quenched upon urea being enzymatically converted into ammonia and carbon dioxide.
109 , 22:6 n-3) is abundant in the retina and is enzymatically converted into pro-homeostatic docosanoids
113 ive vasodilative and reno-protective axis by enzymatically converting Ang II to angiotensin-(1-7) (An
114 ifications in the Leishmania major genome by enzymatically converting these modifications into abasic
117 methods, the surface-bound DNA molecules are enzymatically copied into their RNA complements from a s
118 ngth, were found to encode the pmoC gene, an enzymatically critical subunit of the particulate methan
119 at MSCs can easily deform unless the film is enzymatically cross-linked, which promotes the spreading
122 monomers before dimerizing to form multiple enzymatically deficient roadblocks that may inhibit reve
126 sults provide a further understanding of how enzymatically-degradable multi-stage polymeric carriers
127 ing to lysosomes where the quasi-envelope is enzymatically degraded and uncoating ensues coincident w
128 and prostaglandin F2alpha (PGF(2alpha)), are enzymatically degraded by 15-hydroxyprostaglandin dehydr
131 We optimized an MS assay to quantify the enzymatically dephosphorylated peptide reaction product
133 labeled on all four amino sugar residues and enzymatically derivatized to produce a library of 15 gly
135 been prepared by engaging derivatives of an enzymatically derived and homochiral cis-1,2-dihydrocate
136 onide derived from enantiomerically pure and enzymatically derived cis-1,2-dihydrocatechol 3, elabora
137 , which is available in eight steps from the enzymatically derived cis-1,2-dihydrocatechol 8, engages
138 -bound RNA primer, and the DNA templates are enzymatically destroyed, leaving behind the desired RNA
141 /- 2.94 nM on LNCaP; K(i) = 0.37 +/- 0.21 nM enzymatically determined) and highly efficient internali
142 ith ethylene in plant cells and is primarily enzymatically detoxified by the mitochondrial beta-CYANO
145 two most abundant, i.e. Prunin 1 and 2, were enzymatically digested in silico predicting 10 and 14 pe
147 er chemically fixed by coronary perfusion or enzymatically digested to isolate ventricular myocytes,
148 from MAIs, while chondroitinase ABC (ChABC) enzymatically digests CSPGs, which are upregulated at th
149 r these endogenous hydrolase enzymes) can be enzymatically disrupted, finally contributing to the deg
151 l Cas13 proteins studied to date possess two enzymatically distinct ribonuclease activities that are
152 ment reactions have been combined with other enzymatically driven processes and have also been employ
153 pathway of vitamin K, that this reaction is enzymatically driven, and that a selection pressure is o
154 is completely stereoretentive, parlaying the enzymatically established beta-C-O stereochemistry in th
155 rboxylcytosine (caC), which were shown to be enzymatically excised and then replaced with an unmodifi
158 reported cases, this approach is limited to enzymatically facilitated mechanisms that each target na
160 ilizes the difference in endocytic uptake of enzymatically formed peptide assemblies to selectively k
163 quantification of H2O2, because it is often enzymatically generated at biosensors as a reporter for
166 polymer facilitates the "wiring" of in situ enzymatically generated CdS QDs, which photocatalyze oxi
168 d the sensitivity and precision, towards the enzymatically generated ferrocyanide species, over a pla
169 rial haem-containing receptor for endogenous enzymatically generated NO(*) has not been identified pr
170 ese results expand the chemical diversity of enzymatically generated TNA molecules to include a hydro
173 lation (liquid seasoning) was produced using enzymatically hydrolysed poultry proteins isolate (PPI).
177 ion of pyrazines in model systems containing enzymatically hydrolyzed whey protein under dry heating
182 ach to generate a set of affinity optimized, enzymatically inactivated ACE2 variants that potently bl
183 RSS1R122H mice with PRSS1WT mice, as well as enzymatically inactivated Dead-PRSS1R122H mice, we unrav
185 d murine macrophages expressing either WT or enzymatically inactive (p.C284A) procaspase-1 fusion rep
186 Here we show that knockin mice expressing an enzymatically inactive acidic mammalian chitinase (AMCas
188 e acetylation-deficient Lys258Arg mutant was enzymatically inactive and failed to rescue growth of AC
189 terspaced short palindromic repeats (CRISPR)-enzymatically inactive Cas9 in MVM-infected cells increa
190 enes based on the inducible expression of an enzymatically inactive Cas9 protein together with gene-s
193 at Wnt and CSC inhibition is mediated by the enzymatically inactive form of 5-LO, which hinders nucle
194 icantly suppresses HBV replication, while an enzymatically inactive form of TAK1 exerts no effect.
198 retreatment of HAE cells with HE but not the enzymatically inactive mutant blocked hCoV-HKU1 infectio
199 t increase in eVP40 VLP egress, and (iii) an enzymatically inactive mutant of WWP1 (C890A) did not ub
201 ization was also enhanced by PREP(S554A), an enzymatically inactive PREP mutant, but this was not aff
203 with an S178A substitution (SsE(S178A)), an enzymatically inactive SsE mutant protein, was generated
207 the first time that pyroptosomes containing enzymatically inactive variant p.C284A caspase-1 spread
208 d that TAT-STEP, a peptide that renders STEP enzymatically inactive, prevented cocaine-induced reduct
211 owever, a significant proportion of HYAL2 is enzymatically inactive; thus the mechanisms through whic
212 We demonstrate that conditioning hiNPC with enzymatically-inactive tissue-type plasminogen activator
213 nner wherein one molecular building block is enzymatically incorporated in a sequence that correspond
214 kDa (CPE/NF-alpha1)-DeltaN has an important, enzymatically independent role in the regulation of gene
217 roup and the unusual enzymology involved, we enzymatically interrogated diverse thiolactomycin analog
218 onists on coronary smooth muscle cells (CSM) enzymatically isolated from lean, healthy Ossabaw miniat
219 otinylated RNA oligomer bearing a single m6A enzymatically labelled with a commercial conjugate of st
220 ically, sticky ends at crystal contacts were enzymatically ligated, and the covalent bonds significan
221 yglutarate is oxidized to 2-oxoglutarate non-enzymatically, likely via iron-mediated Fenton-chemistry
222 yglutamylation, where a glutamate residue is enzymatically linked to the gamma-carboxyl group of a gl
225 we examined primary mouse hepatocytes after enzymatically manipulating the cellular content of DAG o
226 ed how the natural food colorant, bixin, was enzymatically modified by appending sorbitol to the bixi
229 the simultaneous quantification of numerous enzymatically modified RNAs in a biological sample, conv
230 eral nerve graft into the lesion cavity, and enzymatically modulated the inhibitory glial scar distal
231 es (CD71+) targeted by P. vivax invasion are enzymatically normal, even in hemizygous G6PD-Mahidol G4
232 ked and DNA modifications are then converted enzymatically or chemically to strand-breaks for both 3'
235 demonstrate a central role for procoagulant enzymatically oxidized phospholipids (eoxPL) in regulati
238 ere, we report poliovirus in complex with an enzymatically partially deglycosylated form of the 3-dom
239 (tz) ATP to yield N(tz) AD(+) , which can be enzymatically phosphorylated by NAD(+) kinase and ATP or
240 ologically important structures derived from enzymatically post-glycosylational modifications of glyc
241 pre-adenylated adapters can be chemically or enzymatically prepared, enzymatic adenylation is preferr
243 ewly synthesized polypeptides have to become enzymatically processed, folded, and assembled into olig
246 lytic amplification for the detection of the enzymatically produced hydrogen peroxide and acted as an
247 l characterization of bioconjugate vaccines, enzymatically produced in glycoengineered Escherichia co
250 is a 136-fold increase in brightness for the enzymatically produced reporter versus probe precursor,
251 lution phase of inflammation is regulated by enzymatically produced specialized pro-resolving mediato
254 al intermediate benzoyl-coenzyme A, which is enzymatically reduced to cyclohexa-1,5-dienoyl-CoA.
256 on liquid chromatography (HILIC) analysis of enzymatically released and fluorescently labeled glycans
258 and flour may contain hidden DON that may be enzymatically released during the breadmaking process wh
260 gradation of endogenously present lipids and enzymatically released lysolipids caused loaf volume to
262 y of N-glycan structures in sand fly saliva, enzymatically released sugars were fluorescently tagged
263 ucceeded by analysis of neoglycoproteins and enzymatically remodeled glycoproteins to verify carbohyd
265 tes an oligomannosylated N-glycopeptidome by enzymatically removing sugars outside the N-glycopeptide
266 s bearing a hydroxyalkyl side chain could be enzymatically resolved, providing access to enantiomeric
269 ylene glycol) hydrogels providing sustained, enzymatically-responsive peptide release were exploited
270 east partially reversible (i.e., they can be enzymatically reversed after cessation of exposure to en
271 l-CoAs are reactive metabolites that can non-enzymatically S-acylate and N-acylate protein cysteine a
272 uvate, glutamate, glycerol and urea measured enzymatically showed an expected gradual ischemic and ce
274 describe different routes to the creation of enzymatically stable mimetics of IDR-1018 and identify a
275 four natural nucleotides, it is possible to enzymatically synthesize a micrometer-sized, single-stra
276 that both in vivo cell-produced and in vitro enzymatically synthesized insoluble glucans displayed pr
277 s has been realized by integrating different enzymatically-tagged competitive and sandwich immunoassa
278 + interneurons in the mPFC, we have digested enzymatically these structures and have found a decrease
279 DNA base in mammalian cells, can be oxidized enzymatically to 5-hydroxymethylcytosine (5hmC), 5-formy
280 rived adenosine was removed from the extract enzymatically to analyze its role in ragweed-induced all
282 ivery and enables targeted agents to partner enzymatically to generate enhanced biologic effect.
284 o-fibril morphological switch is achieved by enzymatically transferring the farnesyl group of the far
285 roup and have moderate steric hindrance were enzymatically transformed, likely by phosphorylation.
290 Finally, Zimm plot analysis revealed that enzymatically treated polymers differ with respect to th
295 cally detected through stripping analysis of enzymatically (using alkaline phosphatase) deposited sil
297 odulating cholesterol binding genetically or enzymatically, we could switch the TCR between the resti
298 leotides and their analogues can be obtained enzymatically, which is often restricted to natural subs
299 lite byproduct of glycolysis that reacts non-enzymatically with nucleophiles in cells, including basi