ライフサイエンスコーパス: epidemic

1 the 2013-16 west African Ebola virus disease epidemic).

2 ressing the opioid crisis and Ending the HIV Epidemic.

3 oach can be an important tool Ending the HIV Epidemic.

4 umber and the exponential growth rate of the epidemic.

5 ation and contact tracing needed to stop the epidemic.

6 an important opportunity to help end the HIV epidemic.

7 atiotemporal dynamics of the opioid overdose epidemic.

8 eir addictive potential has sparked a misuse epidemic.

9 (AF) are rising, justifying the term global epidemic.

10 e prevention and control of this devastating epidemic.

11 hole population and help resolve the obesity epidemic.

12 serious threat to controlling the global TB epidemic.

13 V research, care, and efforts to end the HIV epidemic.

14 ventions, based on modeling of the unfolding epidemic.

15 confirming our records about the peak of the epidemic.

16 clinical problem associated with the obesity epidemic.

17 trol the current worldwide human coronavirus epidemic.

18 racial, and gender diversity in this global epidemic.

19 rganization has declared obesity as a global epidemic.

20 as successfully used during the 2013-16 EBOV epidemic.

21 esented a priority in the early phase of the epidemic.

22 to disrupt new transmissions and end the HIV epidemic.

23 rates and monitoring the progression of the epidemic.

24 l efforts in the early stages of an emerging epidemic.

25 tion are effective tools to help end the HIV epidemic.

26 s, based only on a single realisation of the epidemic.

27 te significantly to sustaining the local HIV epidemic.

28 hus leading to their dominance in the global epidemic.

29 opulation of Geneva, Switzerland, during the epidemic.

30 ing the mortality associated with the opioid epidemic.

31 es and the implications of an anticipated HF epidemic.

32 to track and inform actual recovery from an epidemic.

33 or the growth rate of any infectious disease epidemic.

34 cessary to achieve an end to the global STIs epidemic.

35 or reliably identifying the conclusion of an epidemic.

36 continues to experience a generalized HIV-1 epidemic.

37 disease that may exist concurrently with the epidemic.

38 ignificant contributor to the current opioid epidemic.

39 African countries have the most diverse HIV epidemics.

40 to help manage mosquito-transmitted disease epidemics.

41 ons of severe cases of disease during annual epidemics.

42 the effect on human as well as plant disease epidemics.

43 n immunodeficiency virus and opioid overdose epidemics.

44 ble of mitigating the effects of future Zika epidemics.

45 ce to controlling current and future cholera epidemics.

46 spatially and temporally distributed during epidemics.

47 efforts needed to achieve elimination of YF epidemics.

48 ublic of the Congo have the most diverse HIV epidemics.

49 es worldwide could experience more prolonged epidemics.

50 ardiovascular events during annual influenza epidemics.

51 al treatments to prevent substantial malaria epidemics.

52 in the context of recent respiratory disease epidemics.

53 uthern states were identified with rural HIV epidemics.

54 nt infection during experimental and natural epidemics.

55 nd other countries struggling with expanding epidemics.

56 spersal history and transmission dynamics of epidemics.

57 ich altered parasite assembly during natural epidemics.

58 ry-wide public policies to control local HIV epidemics.

59 nmental and virological drivers of influenza epidemics.

60 frica for fast-tracking the end of their HIV epidemics.

61 d reduced access, sometimes fueling national epidemics.

62 d on 1 March 2020 followed by a severe local epidemic(1).

63 calized outbreaks of disease into widespread epidemics(1-4).

64 However, a month into the epidemic, a novel multisystem inflammatory syndrome in c

65 ties will be crucial for the "Ending the HIV Epidemic: A Plan for America" (EHE) initiative, in which

66 c variants that could be associated with its epidemic ability.

67 waves, now that countries have reduced their epidemic activity and progressively phase out lockdown.

68 drift of neuraminidase was a major driver of epidemic activity, indicating that neuraminidase-based v

69 The COVID-19 epidemic affected a large proportion of patients at this

70 The human immunodeficiency virus (HIV) epidemic among adolescent girls and young women (AGYW) i

71 considerable value; however, ending the HIV epidemic among PWID will require innovative implementati

72 eatment need suggest that control of the HCV epidemic among PWUD will require expansion of HCV treatm

73 ter was found, indicating an independent sub-epidemic among this group.

74 obally HIV incidence is slowing, however HIV epidemics among sex workers are stable or increasing in

75 ssary to affect the trajectory of the opioid epidemic and associated infections.

76 and add nuance to our genomic definitions of epidemic and endemic cholera, and are of direct relevanc

77 racterise the variation within, and between, epidemic and endemic V. cholerae.

78 in coronavirus research made before the SARS epidemic and how they inform current research on the new

79 k-wearing, although effective in slowing the epidemic and in reducing mortality, would also be ineffe

80 sk factor on candidemia; however, the opioid epidemic and increases in IDU may be changing the epidem

81 ovides novel insight into the Nigerian HIV-1 epidemic and may have implications for future HIV-1 prev

82 nterventions were undertaken to mitigate the epidemic and prevent the persistence of the virus in hum

83 ow genomic analyses should be used during an epidemic and propose that phylogenetic insights from the

84 lar injury is a major cause of CKD, which is epidemic and without therapeutic options.

85 he threshold, probability, and final size of epidemics and 2) exploring the interplay between the str

86 eprint list of viruses likely to cause major epidemics and for which no, or insufficient countermeasu

87 aluable in the monitoring and forecasting of epidemics and outbreaks, it is evident that such infodem

88 a global public health burden due to annual epidemics and pandemic potential.

89 that are crucial for practical management of epidemics and prediction of pandemic risk.

90 to the COVID-19 pandemic, as well as future epidemics and public health emergencies.

91 vide real-time monitoring and control of the epidemic, and even support targeted drug screening and d

92 e study period being relatively early in the epidemic, and more-elaborate policy responses were not y

93 health contingency planning for future Ebola epidemics, and help better allocate resources and evalua

94 to 650,000 deaths per year through seasonal epidemics, and pandemics have caused tens of millions of

95 Zoonosis-based epidemics are inevitable unless we revisit our relations

96 Bluetongue virus (BTV) epidemics are responsible for worldwide economic losses

97 tion of local transmission in sustaining the epidemic, as well as a complex viral migration network a

98 f the world who have not yet confronted this epidemic, as well as in those forecasting a possible sec

99 s marked European history with a devastating epidemic at the end of the 15(th) century.

100 We jointly model the US epidemic at the state-level, using publicly available de

101 gainst precise forecasts of the evolution of epidemics based on mean-field, effective, or phenomenolo

102 om young CF patients, are outcompeted by the epidemic Bcc isolate Burkholderia cenocepacia strain AU1

103 a, and the lowest numbers of cases since the epidemic began were reported in 2019.

104 used as a key indicator for the size of the epidemic, but the observed number of deaths represents o

105 uired infection has been reported in similar epidemics, but there are limited data on the prevalence

106 ased shows considerable variation in how the epidemic can appear to individuals on the ground, potent

107 e surveillance during the later phases of an epidemic can therefore substantially mislead policymaker

108 hted by the current coronavirus disease 2019 epidemic, caused by the novel severe acute respiratory s

109 Regionally, epidemic cholera is contained to the island of Hispaniol

110 he 1992-1998 cholera epidemic, the invariant epidemic clone co-existed alongside highly diverse membe

111 hese interventions will be enough to achieve epidemic control (incidence of 1 infection per 1000 pers

112 e dengue infection samples is imperative for epidemic control and public health in tropical regions b

113 s for laboratory diagnostic tests and hamper epidemic control or patient treatment efforts.

114 merous fields, including traffic management, epidemic control, and stock market dynamics.

115 ion interventions, are needed to achieve HIV epidemic control.

116 ol measures be adopted four weeks later, the epidemic could have lasted 49 days longer (95% CI: 31-68

117 as had a significant socioeconomic impact on epidemic countries.

118 emic spreading processes by "flattening" the epidemic curve and delaying the spread to geographically

119 ts of different control strategies after the epidemic curve has been flattened.

120 ic planning for the far side of the COVID-19 epidemic curve should consider local strategies for reop

121 three states were on track to curtail their epidemic curve.

122 ting an age-structured mathematical model to epidemic data from China, Italy, Japan, Singapore, Canad

123 h disease-specific) waiting times for end-of-epidemic declarations that cannot accommodate these vari

124 infectious clone of an enteric CoV, porcine epidemic diarrhea virus (icPEDV), we generated viruses w

125 e genetic system for an enteric CoV, porcine epidemic diarrhea virus (PEDV), and outline an approach

126 Densoviruses cause lethal epidemic disease in invertebrates, including shrimp, coc

127 This requires extensive sampling of epidemic disease over time, alongside the background of

128 paramyxoviruses, airborne agents that cause epidemic diseases in animals including humans.

129 The epidemic doubling time in the United States was 2.68 day

130 gies were strongly associated with increased epidemic doubling time.

131 ogen spread in a population, we propose that epidemics drive lifespan setpoints' evolution.

132 ns that allow immune escape impact influenza epidemic dynamics at the population level.

133 The overdose epidemic emerged and increased in amplitude among the 19

134 when these trials are carried out in future epidemic emergencies.

135 28,000 reported infections; this devastating epidemic emphasized the need to understand the mechanism

136 ribute to the United States' "Ending the HIV Epidemic" (EtHE) initiative.

137 achieving population-level impact on the TB epidemic, even in high-HIV-burden settings, will require

138 utocorrelation analysis showed that the HFRS epidemic exhibited the characteristic of highly spatiall

139 e E2 lineage, which is more prevalent during epidemics, exhibits a combination of allelic variants th

140 weekly effect is at least partly due to non-epidemic factors.

141 he midst of a rapidly spreading, devastating epidemic for which there was no effective treatment.

142 e Great Plague of 1665, we estimate that the epidemic growth rate increased fourfold.

143 The current opioid injection drug use epidemic has been associated with an increase in hepatit

144 ethod for estimating the probability that an epidemic has been eliminated (i.e. that no future local

145 Control of the TB epidemic has been limited by lengthy drug regimens, anti

146 One approach to address the opioid epidemic has been to create prescribing consensus report

147 In the United States, the opioid epidemic has increased the number of overdose deaths wit

148 The opioid epidemic has led to increases in injection drug use (IDU

149 he novel coronavirus disease 2019 (COVID-19) epidemic has spread from China to 25 countries.

150 The COVID19 epidemic has spurred a global public health crisis.

151 The "Opioid Epidemic" has generated a drive for a deeper understandi

152 r months to years after CHIKV infection, and epidemics have a severe economic impact.

153 cent Zika virus (ZIKV) and chikungunya virus epidemics highlight the explosive nature of arthropod-bo

154 1, transmission is high enough to sustain an epidemic; if R(0) is less than 1, it is not.

155 ily spread efficiently via mosquitoes during epidemics.IMPORTANCE Although Zika virus infection of pr

156 was 3-fold higher, amplified by a serotype 1 epidemic in 2011.

157 dynamics: one community can sustain a micro-epidemic in another community in which transmission is t

158 transmission dynamics of the HIV-1 CRF55_01B epidemic in China at high resolution.

159 growth and limited the size of the COVID-19 epidemic in China, averting hundreds of thousands of cas

160 testing and contact tracing on the COVID-19 epidemic in each state.

161 -based microsimulation model of the COVID-19 epidemic in France.

162 d inform policies for control of the obesity epidemic in India and other urbanising LMICs.

163 The human immunodeficiency virus (HIV) epidemic in India is concentrated among 3.1 million men

164 he bereavement burden over the course of the epidemic in lockstep with rising death tolls.

165 k and human RVF case data from the 2018-2019 epidemic in Mayotte to estimate viral transmission among

166 simulation model of the spatial spread of an epidemic in order to examine the impact of a pathogen's

167 Our findings show that the TB epidemic in prisons represents one of the most important

168 We use a mathematical model of the HIV epidemic in South Africa to simulate CAB LA uptake by po

169 ently underrecognized threat, an eventual HF epidemic in the densely populated South Asian nations co

170 infer differences in the progression of the epidemic in the three locations.

171 Obesity is becoming an epidemic in the United States and worldwide and increase

172 The ongoing substance misuse epidemic in the United States is complex and dynamic and

173 V transmission and potentially eliminate the epidemic in these areas.

174 ion aggregation and heterogeneity, such that epidemics in crowded cities are more spread over time, a

175 p us determine how they fuel the generalised epidemics in SSA.

176 d MERS-CoV have caused serious outbreaks and epidemics in the past eighteen years.

177 piratory syndrome coronavirus 2 (SARS-CoV-2) epidemics in the world.

178 (<1% each), they were prominent in regional epidemics, including in east and southeast Asia, west an

179 The obesity epidemic increases the interest to elucidate impact of s

180 DS, and partners is used to estimate key HIV epidemic indicators from mathematical models.

181 reach national targets of the ending the HIV epidemic initiative by 2030.

182 2) opportunities offered by the "End the HIV Epidemic" initiative; and (3) policy changes necessary t

183 The current opioid epidemic is one of the most severe public health crisis

184 to a short period of time (peakedness of the epidemic) is strongly shaped by population aggregation a

185 y uniform population in the Northeast, where epidemic LB now constitutes the most important vector bo

186 ring the coronavirus disease 2019 (COVID-19) epidemic, many countries have instituted population-wide

187 ks are a result of the nonlinear dynamics of epidemics (Mclean et al., Epidemiol.

188 Here, we use a climate-dependent epidemic model to simulate the SARS-CoV-2 pandemic by pr

189 In our work, we adapt a traditional SEIR epidemic model to the specific dynamic compartments and

190 ectories of both RSV and influenza, using an epidemic model.

191 and transmissions risks and integrated with epidemics models to further assess the public health out

192 related toxins, produced by USA300 and other epidemic MRSA clones.

193 The current opioid epidemic necessitates a better understanding of human ad

194 the mode of plague transmission in any given epidemic; nevertheless, order-of-magnitude estimates of

195 Since 2002, a global epidemic of acute hepatitis C virus (HCV) infection has

196 ence of SARS-CoV-2 and the ensuing explosive epidemic of COVID-19 disease has generated a need for as

197 and an aging population has given rise to an epidemic of diabetes mellitus-induced heart failure.

198 zil in 2015, Zika virus (ZIKV) has caused an epidemic of fetal congenital malformations within the Am

199 The worldwide dual epidemic of obesity and type 2 diabetes is an important

200 December 2019 saw the emergence of a new epidemic of pneumonia of varying severity, called corona

201 s, necessary to achieve an end to the global epidemic of sexually transmitted infections.

202 st Nile virus, and the most recent explosive epidemic of Zika virus in the Americas.

203 us times during the last 70 years, including epidemics of dengue virus and West Nile virus, and the m

204 recognized for thousands of years, as annual epidemics of the common cold and influenza disease hit t

205 prospective observational study done during epidemics of Zika and chikungunya viruses in Recife, Per

206 Our goal was to understand the impact of the epidemic on kidney transplantation (KT), at both the nat

207 this spillover resulted in the largest HPAI epidemic on record in Europe and was associated with an

208 To tackle this, epidemics on networks are approximated by a Birth-and-De

209 emperature and humidity do not predict local epidemic onset timings.

210 during five consecutive years, including the epidemic outbreak year (2016).

211 During major epidemic outbreaks, demand for healthcare workers (HCWs)

212 ruses are responsible for a number of recent epidemic outbreaks.

213 atients with COVID-19 and for monitoring the epidemic over time.

214 hee Salmonella attacks, the threat of future epidemics/pandemics and/or terrorist/criminal use of pat

215 del to the specific dynamic compartments and epidemic parameters of COVID 19, as it spreads in an age

216 evertheless, order-of-magnitude estimates of epidemic parameters suggest that the observed slow growt

217 cline of cases and fatalities after apparent epidemic peaks has not been rapid.

218 onential outbreak dynamics with lower, later epidemic peaks.

219 tes likely viral circulation during the post-epidemic period.

220 During the early epidemic phase, we found that SARS-CoV-2 spread mostly l

221 Ebola virus (EBOV) epidemics pose a major public health risk.

222 seroprevalence utility as a predictor of HIV epidemic potential among female sex workers (FSWs) globa

223 HSV-2 is a strong predictor of HIV epidemic potential among FSWs.

224 ew pathogenic strains including strains with epidemic potential as a direct consequence of genetic ex

225 ) genes have spread primarily via the single epidemic pOXA-48-like plasmid, which emerged recently in

226 es for Health Research (NIHR), Coalition for Epidemic Preparedness Innovations, NIHR Oxford Biomedica

227 The COVID-19 epidemic presents the scientific community with an oppor

228 ve side, enough is currently known about the epidemic process to permit the construction of mathemati

229 ent quantitative descriptions of nonstandard epidemic profiles are either abstract, phenomenological,

230 h fatal overdoses following relapse reaching epidemic proportions and disease-associated costs contin

231 Chronic liver disease is reaching epidemic proportions with the increasing prevalence of o

232 t.SIGNIFICANCE STATEMENT Obesity has reached epidemic proportions, and the associated health conseque

233 e decrease in ZIKV cases since the 2015-2016 epidemic, questions concerning the prevalence and longev

234 upt transmission will still lead to COVID-19 epidemics rapidly overwhelming health systems, with subs

235 (OPSCC) incidence is increasing at a nearly epidemic rate, largely driven by the human papillomaviru

236 es to impede the spread of sustained measles epidemics, rather than favoring it.

237 nsensus around characteristics of successful epidemic recovery, applying these metrics to support pre

238 environmental transmission in the ecology of epidemics remains a persistent challenge.

239 Global elimination of YF epidemics requires higher population-level immunity than

240 and human colonic organoids, that TcdB from epidemic ribotype 027 strains does not require Frizzled

241 Nevertheless, the epidemic's overall effect on the RRT population remained

242 We assessed two main epidemic scenarios for a period of 360 days, with an R(e

243 ealth services under four different COVID-19 epidemic scenarios.

244 fants hospitalized with bronchiolitis over 6 epidemic seasons (2012-2013 to 2017-2018) was carried ou

245 7 and 2017-2018 and changed according to the epidemic seasons only.

246 In an epidemic setting, the application of the four categories

247 trolled trials remain indispensable tools in epidemic settings and also provides guidance on how to a

248 re population could be cost-effective in all epidemic settings.

249 eed for diverse prognostic tools considering epidemic severity, age, sex and transmission.Clinical Tr

250 Spatiotemporal epidemic simulations demonstrated that control of pathog

251 luenza A viruses (IAVs) have caused seasonal epidemics since 1977.

252 antigenic change has no consistent effect on epidemic size.

253 b lineages was a key driver for their global epidemic spread and outstanding evolutionary success.

254 Epidemic spread is characterized by exponentially growin

255 scussed, including spatial disease patterns, epidemic spread of pathogens, crop characteristics, and

256 We analyzed key parameters of epidemic spread to estimate the contribution of differen

257 varying this single parameter and simulating epidemic spread, we are able to identify how more freque

258 ctural changes have a considerable effect on epidemic spreading processes by "flattening" the epidemi

259 ogeneity can impact how fast and how much an epidemic spreads.

260 esity, and metabolic diseases has reached an epidemic status worldwide.

261 acute pneumonia compared to USA300 (current epidemic strain and commonly used in research) and had r

262 ially reputed to be less pathogenic than the epidemic strains from Europe 1 lineage.

263 For epidemics such as macro-parasitic diseases, detailed mod

264 explain how A. aegypti can sustain explosive epidemics such as ZIKV despite relatively poor vector co

265 and animal origin of 2019-nCoV and may help epidemic surveillance and preventive measures against 20

266 etween the Black Death of 1348 and the later epidemics that culminated with the Great Plague of 1665,

267 ence and socio-spatial human behavior during epidemics that exhibit nonstandard incidence patterns.

268 We show that, during the 1992-1998 cholera epidemic, the invariant epidemic clone co-existed alongs

269 great interest in describing the dynamics of epidemics, they struggle to fully capture the geospatial

270 uch progress has been made in treating these epidemics, this has led to a rise in liver complications

271 well as stochastic simulations to derive the epidemic threshold, which decreases substantially with t

272 rgery contribute to the United States opioid epidemic through persistent use past the postoperative p

273 The emergence of viral epidemics throughout the world is of concern due to the

274 resistance and focuses on the country-level epidemic, thus ignoring subnational variations in HIV an

275 tically severe cases, ranging from sustained epidemics to near elimination.

276 The potential for these viruses to sustain epidemic transmission among humans is poorly understood.

277 he effect of key geographic factors on local epidemic transmission is lacking(7).

278 tact, have proven successful in bringing the epidemic under control.

279 xcess perforations attributed to the typhoid epidemic, using temporal trends in S. Typhi bloodstream

280 Argentina, and we contrast the clonality of epidemic V. cholerae with the background diversity of lo

281 cales, the timing, duration and magnitude of epidemics vary substantially, but the underlying causes

282 Epidemic viral infections predominated as causes of chil

283 RS-CoV-2 lineages into California, including epidemic WA1 strains associated with Washington state, w

284 Likewise, outside the epidemic wave and with the return of other respiratory d

285 slightly above 20% in both groups after the epidemic wave subsided by the end of May.

286 At the end of the epidemic wave, crude and age-standardized cumulative inc

287 aining public health measures to avoid a new epidemic wave.

288 t macrolide-resistant isolate in 1998, three epidemic waves of macrolide-resistant GAS infections hav

289 identify wild populations at risk of disease epidemics, we must elucidate the factors that shape, and

290 ates (95% CI) for the 2013-2016 West African epidemic were 82.8% (45.6-85.6%) overall and 89.1% (40.8

291 greater importance in the era of the COVID19 epidemic, when sleep labs were closed and most studies w

292 responsible for globally-spread tuberculosis epidemics, whereas TbD1-intact "ancestral" lineages tend

293 asingly prominent in global and regional HIV epidemics, which has important implications for the deve

294 se (NAFLD) represents a burgeoning worldwide epidemic whose etiology reflects multiple interactions b

295 Successfully addressing the epidemic will require advances in basic science, develop

296 (NAFLD) is considered the next major health epidemic with an estimated 25% worldwide prevalence.

297 In a generalized HIV epidemic with continuum of care levels at 90-90-90, impr

298 Ebola virus (EBOV) causes epidemics with high mortality yet remains understudied d

299 fected humans and livestock animals to cause epidemics with significant morbidity and mortality.

300 Epidemic ZIKV strains contain capsid mutations that incr