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1 ctrophotometric analysis revealed that nerve epidermal growth factor-like 1 (NELL1) immune complexes
3 describe four biopsy-proven cases of neural epidermal growth factor-like 1 (NELL1)-associated membra
5 ug-induced membranous nephropathy are neural epidermal growth factor-like 1 and proprotein convertase
6 ajor cause of nephrotic syndrome, and neural epidermal growth factor-like 1 protein (NELL1) is the se
7 ociated with one antigen (such as for neural epidermal growth factor-like 1); ( 3 ) rare presence of
9 at the avB5 integrin ligand milk fat globule epidermal growth factor like 8 (MFGE8) regulates cellula
10 ding of the integrin ligand milk fat globule epidermal growth factor like 8 (MFGE8) to the alphavbeta
12 SK9) is a secreted protein that binds to the epidermal growth factor-like-A domain of the low density
13 as tomoregulin or transmembrane protein with epidermal growth factor-like and 2 follistatin-like doma
14 , epidermal growth factor-like, laminin-type epidermal growth factor-like, and link domain-containing
15 e N-terminal end, proline-rich C region, and epidermal growth factor-like calcium-binding (EGF-cb) do
16 o repeated module types: the calcium binding epidermal growth factor-like (cbEGF) domain and the tran
17 We have used recombinant calcium binding epidermal growth factor-like (cbEGF) domain fragments fr
18 rganisation that includes 43 calcium binding epidermal growth factor-like (cbEGF) domains and seven t
19 rganisation that includes 43 calcium-binding epidermal growth factor-like (cbEGF) domains arranged as
20 dominantly composed of eight calcium-binding epidermal growth factor-like (cbEGF) domains, each of wh
22 conformation of fibrillin-1 calcium-binding epidermal growth factor-like (cbEGF-like) domains within
23 with subsequent release of its extracellular epidermal growth factor-like-containing domain and autoc
27 The functional importance of the N-terminal epidermal growth factor-like domain (EGF-N) of factor X/
28 rombin-sensitive region (TSR), and the first epidermal growth factor-like domain (EGF1) of protein S,
29 polypeptides in which residues in the third epidermal growth factor-like domain (EGF3) are mutated d
30 f conserved aspartate/asparagine residues in epidermal growth factor-like domain (EGFD) proteins.
31 g the single transmembrane receptor multiple epidermal growth factor-like domain 10 (MEGF10) cause an
34 this method, we developed an assay for human epidermal growth factor-like domain 7 (EGFL7), an extrac
36 ammalian uPA by lacking two cysteines of the epidermal growth factor-like domain and a uPAR-binding s
37 ctor VIII allows the factor IXa protease and epidermal growth factor-like domain binding sites (local
38 2 (HER2) receptor tyrosine kinase through an epidermal growth factor-like domain in its extracellular
40 We have cloned, expressed, and purified the epidermal growth factor-like domain of murine uPA alone
41 oneoplastic potential in comparison with the epidermal growth factor-like domain of neuregulin-1beta
42 amino-acid residue within the fifth laminin-epidermal growth factor-like domain of the USH2A gene an
43 ats 1-2 and 6-8 of tenascin-R but not to the epidermal growth factor-like domain or the fibrinogen-li
44 mmation, but the function of the recombinant epidermal growth factor-like domain plus serine/threonin
45 a chimeric Factor IX by replacing the first epidermal growth factor-like domain with that of Factor
46 motif, (iii) a cysteine-rich domain, (iv) an epidermal growth factor-like domain, (v) a hydrophobic t
48 arginine at a highly conserved residue of an epidermal growth factor-like domain, impairs Wnt signali
50 ipocyte factor-1 (Pref-1) is a transmembrane epidermal growth factor-like domain-containing protein h
54 y lacking the exon encoding the uPAR-binding epidermal growth factor-like domain; zfuPA-b differs fro
55 alloendopeptidase isolated from crayfish, an epidermal growth-factor-like domain, and three regions o
64 E1 (tyrosine kinase with immunoglobulin- and epidermal growth factor-like domains 1) missense variant
66 y demonstrated that upregulation of multiple epidermal growth factor-like domains 11 (MEGF11) gene ex
68 ne-rich tandem repeats encompassing integrin-epidermal growth factor-like domains 2, 3, and 4 of the
69 ntiation-related protein, cysteine-rich with epidermal growth factor-like domains 2, nuclear protein
70 for CD47 in Mac-1 were localized in integrin epidermal growth factor-like domains 3 and 4 of the beta
71 al structure of thrombin in complex with the epidermal growth factor-like domains 4, 5, and 6 of TM (
73 vation of alpha-thrombin in complex with the epidermal growth factor-like domains 4-6 of TM (TM4-6) w
76 d specifically with ErbB2 through one of its epidermal growth factor-like domains and that the co-exp
77 d soluble EMR2, containing highly homologous epidermal growth factor-like domains but a different sta
79 portions encompassing the N-terminal CUB and epidermal growth factor-like domains have been expressed
80 a highly conserved enzyme that hydroxylates epidermal growth factor-like domains in transformation-a
81 atistically significant sequence homology to epidermal growth factor-like domains is found, and a dis
82 plex with a naphthyl inhibitor DX-9065a, two epidermal growth factor-like domains of factor Xa are we
83 to position 274 is highly conserved in other epidermal growth factor-like domains of jagged1 and in t
84 erase 1 (OFUT1), an enzyme that glycosylates epidermal growth factor-like domains of Notch, also has
85 e residues at a strict consensus site within epidermal growth factor-like domains of several serum pr
86 n variants of tenascin-C containing only the epidermal growth factor-like domains or the fibronectin
87 In contrast, no binding was observed to the epidermal growth factor-like domains or to the activatio
88 The structure reveals two tightly packed epidermal growth factor-like domains oriented head to ta
89 181 aa long N-terminal domain containing two epidermal growth factor-like domains, a follistatin moti
90 gamma-carboxyglutamic acid (Gla) domain, two epidermal growth factor-like domains, and a protease dom
91 d stronger blocking compared with mAb to its epidermal growth factor-like domains, and binding was ca
93 domains of BMP1 and mTLL1, devoid of CUB or epidermal growth factor-like domains, have procollagen C
94 ve activity and a transmembrane subunit with epidermal growth factor-like domains, one of which acts
95 ith human fibrillin-2 and had Ca(2+) binding epidermal growth factor-like domains, transforming growt
96 few helical hydrophobic residues and the two epidermal growth factor-like domains, whereas the heavy
101 e a disorder caused by mutations in multiple epidermal-growth-factor-like-domains 8 (MEGF8), which ex
102 , C6PS binds to two sites on FXa, one in the epidermal growth factor-like (EGF) domain and one in the
104 sists of 11 exons with an Ig-like domain, an epidermal growth factor-like (EGF) domain, a beta-stalk,
105 O-Linked fucose modifications on Notch1 epidermal growth factor-like (EGF) domains 8 and 12 enga
109 s studies suggest that O-fucosylation of the epidermal growth factor-like (EGF) repeat in Cripto is e
110 is an unusual form of glycosylation found on epidermal growth factor-like (EGF) repeats and thrombosp
112 st-translational modification that occurs on epidermal growth factor-like (EGF) repeats harboring the
114 y protein O-fucosyltransferase 1 (POFUT1) to epidermal growth factor-like (EGF) repeats in the NOTCH1
118 erase that modifies O-fucose moieties on the epidermal growth factor-like (EGF) repeats of Notch.
119 h activity by modifying O-fucose residues on epidermal growth factor-like (EGF) repeats of Notch.
120 receptors require modification by fucose on epidermal growth factor-like (EGF) repeats of their extr
121 ar domain of mouse Notch1 contains 36 tandem epidermal growth factor-like (EGF) repeats, many of whic
125 comprises multiple copies of ligand binding, epidermal growth factor-like (EGF), and YWTD-type domain
128 nning activity was also inhibited by another epidermal growth factor-like (EGF-like) peptide, neuregu
129 DASIL mutations described to date affect the epidermal growth factor-like (EGF-like) repeats located
130 uregulins (NRGs) are a family of multipotent epidermal-growth-factor-like (EGF-like) factors that ari
133 vulation by regulating the expression of the epidermal growth factor-like family of growth factors.
134 ransmembrane receptor member of the homeotic epidermal growth factor-like family of proteins, partici
136 selectivity of ADAM17 toward Heparin-binding epidermal growth factor like growth factor (HB-EGF), a c
137 pport a critical role for heparin-bound EGF (epidermal growth factor)-like growth factor (HB-EGF) and
138 the increased expression of heparin-binding epidermal growth factor-like growth factor (EGFR ligand)
140 n the ectodomain cleavage of heparin-binding epidermal growth factor-like growth factor (HB-EGF) and
141 ite can activate cleavage of heparin-binding epidermal growth factor-like growth factor (HB-EGF) and
142 rray analysis and identified heparin-binding epidermal growth factor-like growth factor (HB-EGF) as b
144 wth factor was identified as heparin-binding epidermal growth factor-like growth factor (HB-EGF) base
145 growth factor-2 (FGF-2) and heparin-binding epidermal growth factor-like growth factor (HB-EGF) bind
146 igated the effect of VEGF on heparin-binding epidermal growth factor-like growth factor (HB-EGF) expr
159 have recently reported that heparin-binding epidermal growth factor-like growth factor (HB-EGF) mRNA
160 tomy mice, the expression of heparin-binding epidermal growth factor-like growth factor (HB-EGF) prec
161 phtheria toxin (DT) receptor/heparin-binding epidermal growth factor-like growth factor (HB-EGF) prec
166 s study, we demonstrate that heparin-binding epidermal growth factor-like growth factor (HB-EGF), a p
167 cacy of locally administered heparin-binding epidermal growth factor-like growth factor (HB-EGF), a p
171 duction of the growth factor heparin-binding epidermal growth factor-like growth factor (HB-EGF), are
172 that block signaling by the heparin-binding epidermal growth factor-like growth factor (HB-EGF).
173 d v-Jun target, a homolog of heparin-binding epidermal growth factor-like growth factor (HB-EGF).
174 C3s are a dominant source of heparin-binding epidermal growth factor-like growth factor (HB-EGF).
176 recursor of the monkey (Mk) heparin-binding, epidermal growth factor-like growth factor (proHB-EGF) f
177 arin-binding growth factors, heparin-binding epidermal growth factor-like growth factor and fibroblas
178 ibroblast growth factor-2 or heparin-binding epidermal growth factor-like growth factor increases neu
179 ly, in the remodeling phase, heparin-binding epidermal growth factor-like growth factor limits mesenc
181 ouse gene (mHB-EGF) encoding heparin-binding epidermal growth factor-like growth factor was isolated
182 eceptor (EGFR) ligand HBEGF (heparin-binding epidermal growth factor-like growth factor) and a consti
185 factor-alpha, amphiregulin, heparin-binding epidermal growth factor-like growth factor, and sonic he
186 forming growth factor alpha, heparin-binding epidermal growth factor-like growth factor, and Tie-2.
187 d transcripts (amphiregulin, heparin-binding epidermal growth factor-like growth factor, and transfor
188 mphiregulin and its homolog, heparin-binding epidermal growth factor-like growth factor, to the recep
189 ation of membrane content of heparin binding-epidermal growth factor-like growth factor, which serves
192 ese studies demonstrate that LH induction of epidermal growth factor-like growth factors and EGFR tra
195 e receptor, the precursor of heparin-binding epidermal-growth-factor-like growth factor (HBEGF).
197 the alpha subunit genu and between integrin epidermal growth factor-like (I-EGF) domains 1 and 2.
198 w density lipoprotein receptor 1; fasciclin, epidermal growth factor-like, laminin-type epidermal gro
199 rminal (LN) domain followed by three laminin epidermal growth factor-like (LE) domains and a C' regio
200 propeller domain in nidogen bound to laminin epidermal-growth-factor-like (LE) modules III3-5 in lami
202 or the first time that signaling through the epidermal growth factor-like ligand LIN-3 and the LET-23
204 (SFKs), which induce proteolytic shedding of epidermal growth factor-like ligands from the cell surfa
205 y identified a secreted glycoprotein, neural epidermal growth factor-like like 2 (NELL2), in a subtra
206 epidermal growth factor-like protein, neural epidermal growth factor-like-like 2 (NELL2), specificall
207 e identified a secreted Robo3 ligand, neural epidermal growth factor-like-like 2 (NELL2), which repel
208 the extracellular glycoprotein Nell2 (neural epidermal growth factor-like-like 2) is expressed in the
209 binding repeats alone (Ca) or with the third epidermal growth factor-like module (E3Ca), without (Asn
211 sis of constructs comprised of the adjoining epidermal growth factor-like module and the Ca2+ -bindin
212 dly facilitated correct folding of the first epidermal growth factor-like module compared with foldin
213 ial of the human eosinophil surface receptor epidermal growth factor-like module containing mucin-lik
214 the thrombin-sensitive module, and the first epidermal growth factor-like module of human plasma prot
215 ow the human-restricted adhesion-GPCR, EMR2 (epidermal growth factor-like module-containing mucin-lik
217 ely cluster-of-differentiation 97 (CD97) and epidermal-growth-factor-like-module receptor 1 (EMR1)-re
218 nus of ECM1 interacted specifically with the epidermal growth factor-like modules flanking the LG2 su
219 domain of thrombospondins consists of tandem epidermal growth factor-like modules, 13 calcium-binding
222 n, containing two follistatin domains and an epidermal growth factor-like motif that is mainly expres
223 A common feature of proteins that include epidermal growth factor-like motifs is their involvement
224 terminal leucine-rich repeats and C-terminal epidermal growth factor-like motifs, and in Drosophila S
225 containing tandem arrays of calcium-binding epidermal growth factor-like motifs, is present in the b
228 ringe proteins and solutions from docking an epidermal growth factor-like O-fucose acceptor substrate
229 fy the endothelial cell (EC)-secreted factor epidermal growth factor-like protein 7 (EGFL7) as a nove
230 G protein-coupled CC chemokine receptor, and epidermal growth factor-like protein which are found in
231 nstrate that a testicular germ-cell-secreted epidermal growth factor-like protein, neural epidermal g
232 domain, followed by a fixed order of CUB and epidermal growth factor-like protein-protein interaction
235 is a proto-oncogene product that encodes an epidermal growth factor-like receptor tyrosine kinase.
236 uterine pi lineage respond via their LET-23 epidermal growth factor-like receptors to a vulval-deriv
237 l injections of a small peptide encoding the epidermal growth factor-like region of heregulin ectodom
238 ur versions of recombinant C-terminal 19-kDa epidermal growth factor-like region of the major surface
241 in a sequence-specific manner with the first epidermal growth factor-like repeat (EGF-A) in the EGF h
242 pairing similar to the laminin gamma1 chain epidermal growth factor-like repeat 11, suggests conform
243 receptors (LDLRs) in liver by binding to the epidermal growth factor-like repeat A (EGF-A) domain of
244 ding site of PCSK9 has been localized to the epidermal growth factor-like repeat A (EGF-A) domain of
245 ADAMTS-12 selectively binds to only the epidermal growth factor-like repeat domain of COMP of th
247 s, and 1 exon sequence had similarity to the epidermal growth factor-like repeat from several protein
248 he missplicing of exon 34, a calcium-binding epidermal growth factor-like repeat in fibrillin-2 in a
249 a Crumbs isoform that contains an additional epidermal growth factor-like repeat in the extracellular
251 r sex, hypertension history, smoking status, epidermal growth factor-like repeat position and calenda
255 t for binding to Notch, the integrity of the epidermal-growth-factor-like repeat (ELR) 2 is also requ
256 ular domain of NOTCH1 is composed largely of epidermal growth factor-like repeats (EGFs), many of whi
258 an NH2-terminal Gla domain followed by four epidermal growth factor-like repeats and tandem globular
259 gside the well-established O-fucosylation of epidermal growth factor-like repeats by protein O-fucosy
261 A domain of alpha2delta-1 interacts with the epidermal growth factor-like repeats common to all throm
262 vasculature and the presence of Ca2+ binding epidermal growth factor-like repeats contained in the pr
263 rred reduced amounts of O-fucose to secreted epidermal growth factor-like repeats from NOTCH1 or secr
264 icted to occur at consensus sites within the epidermal growth factor-like repeats in the extracellula
265 e thyrotropin receptor (TSHR) ectodomain and epidermal growth factor-like repeats in the laminin gamm
267 nant protein of domain VI and the first four epidermal growth factor-like repeats of domain V, genera
271 id not exhibit reduced fucosylation of these epidermal growth factor-like repeats or thrombospondin t
272 a recombinant protein consisting of only the epidermal growth factor-like repeats showed no cell bind
273 s delta-like/preadipocyte factor-1, contains epidermal growth factor-like repeats that are related to
275 sites for glycosaminoglycan attachment, two epidermal growth factor-like repeats, a putative hyaluro
277 a type-1 membrane protein, 15 extracellular epidermal growth factor-like repeats, and multiple cytop
278 dicted 1713 amino acid protein containing 18 epidermal growth factor-like repeats, four 8-cysteine do
280 er of cysteine residues in the extracellular epidermal growth factor-like repeats, important for liga
281 , a region related to fibrinogen beta/gamma, epidermal growth factor-like repeats, neurexin motifs as
283 act that O-FucT-1 recognizes properly folded epidermal growth factor-like repeats, together with this
288 tion of O-linked fucose residues attached to epidermal growth factor-like sequence repeats of Notch.
289 ghlighting the importance of heparin-binding epidermal growth factor-like signaling in blastocyst-ute
291 e leukemia inhibitory factor (LIF) receptor, epidermal growth factor-like transforming growth factor
292 is believed to be mediated by neuregulin, an epidermal growth factor-like trophic factor released by
293 shares a similar organization of Fasciclin, epidermal growth factor-like, Xlink, and transmembrane d
294 binding domains with a laminin alpha 4 chain epidermal-growth-factor-like/ zinc-finger-like motif.