ライフサイエンスコーパス: epithelia

1 is potent neutralizer directly to the airway epithelia.

2 elative to non-CF controls in differentiated epithelia.

3 traits that improve the characterization of epithelia.

4 increased Slc30a10 expression in mouse ileum epithelia.

5 ells (MCCs) function in fluid clearance over epithelia.

6 e to P. aeruginosa by cystic fibrosis airway epithelia.

7 direct contact between internal and external epithelia.

8 s, might be translatable to other acidifying epithelia.

9 e to a loss of tissue structure in glandular epithelia.

10 a prerequisite for the function of secretory epithelia.

11 y resolved by centripetally migrating limbal epithelia.

12 e bacterial infection persistence in dynamic epithelia.

13 d adaptive immune cells via mucosal and skin epithelia.

14 eatic cancer as compared with healthy ductal epithelia.

15 ll cultures as a model system for intestinal epithelia.

16 ing intracellular uptake and delivery across epithelia.

17 nct from those that elongate bounded, planar epithelia.

18 esponse to mechanical cues in mammalian skin epithelia.

19 d operate in other Drosophila and vertebrate epithelia.

20 raight or curvy strands - observed in native epithelia.

21 -orientated cell divisions in densely packed epithelia.

22 potentially also that of other self-renewing epithelia.

23 rant clone dispersal in developing wing disc epithelia.

24 and/or channel in the paracellular spaces of epithelia.

25 ne cells to long-lived cell-cell contacts in epithelia.

26 bodies to drive cellular turnover in living epithelia.

27 ) channel activity in patient-derived airway epithelia.

28 n-ciliated epithelial cells and mouse airway epithelia.

29 lubricants are toxic to the vaginal mucosal epithelia.

30 Notch signaling inactivation in adult renal epithelia.

31 ional microscopic injury in foregut squamous epithelia.

32 compromised barrier function of the gingival epithelia.

33 spindles in intact Xenopus laevis embryonic epithelia.

34 ins, which maintains structural integrity of epithelia.

35 ugh the cribriform plate, and into the nasal epithelia.

36 d are shaped by mechanisms shared with other epithelia.

37 ty, and develop in a manner resembling other epithelia.

38 ssure to the basolateral surface of alveolar epithelia.

39 o that observed in Notch-signaling-deficient epithelia.

40 how homeostasis is achieved in regenerating epithelia.

41 ucing cells to form a gradient in Drosophila epithelia.

42 lding, bending and invagination of polarized epithelia.

43 human cystic fibrosis (CF) and non-CF airway epithelia.

44 hitectures in monolayer, but not multilayer, epithelia.

45 iscoelastic properties within mesenchyme and epithelia.

46 es (HPVs) infect keratinocytes of stratified epithelia.

47 common feature in SWI/SNF mutant endometrial epithelia.

48 h topological defects were never reported in epithelia.

49 egeneration, and organ size in many types of epithelia.

50 usly affects the development of the adjacent epithelia.

51 by Hh ligands secreted from transformed lung epithelia.

52 peripheral tissues, such as skin and mucosal epithelia.

53 of the turtle vestibular semicircular canal epithelia.

54 tized groups, excluding patients allergic to epithelia.

55 was detected in many FGFR2b ligand-dependent epithelia.

56 paracellular permeabilities in human airway epithelia.

57 generates a directional flow of mucus across epithelia.

58 ed and differentiated by the oral and dermal epithelia.

59 sential for the development and functions of epithelia.

60 ochondrial DNA (mtDNA) compared to noncancer epithelia.

61 to simulate the cellular dynamics of planar epithelia.

62 ifferentiation and function of multiciliated epithelia.

63 scontinuous transcriptomic activation in the epithelia, accompanied with a widespread decidualization

64 y of glycoprotein DMBT1 helps defend mucosal epithelia against microbes.

65 mouse WNT10A mutant palmoplantar and tongue epithelia also display specific differentiation defects

66 -talk is crucial for the dynamic function of epithelia, although how epithelial cells detect and resp

67 r receptor 1 is increased in cystic fibrosis epithelia and activates NF-kappaB signaling, generating

68 acellular Na(+) and water transport in leaky epithelia and alters cancer cell proliferation.

69 uman papillomaviruses (HPVs) infect squamous epithelia and cause several important cancers.

70 detected in olfactory and nasal respiratory epithelia and cilia in animals.

71 ntimicrobial peptide Drosocin in respiratory epithelia and colocalizing fat body domains.

72 n-autonomous mechanical interactions between epithelia and contractile cells.

73 unique roles in development of the adjacent epithelia and endothelia.

74 a regulator of paracellular permeability in epithelia and endothelia.

75 Here, we survey a wide range of Drosophila epithelia and establish that Sdk is a resident protein a

76 ical membrane of sodium-absorbing vertebrate epithelia and evolved as part of a machinery for efficie

77 ome studies can reveal new hypotheses on how epithelia and hair could be affected by daily life envir

78 In zebrafish epithelia and human colon carcinoma cells, Trpv6/TRPV6 e

79 also highly expressed in peripheral neurons, epithelia and immune cells, where their activation may c

80 expression in basal cell layers of the oral epithelia and in immune cells.

81 , we found that simultaneously targeting the epithelia and its microenvironment with ADT and TRC105,

82 Currently, the epithelia and lymphoid germinal centers of the oropharyn

83 essed p120-3 and p120-1, including bronchial epithelia and mammary luminal epithelial cells.

84 f the biological effects of LCs on pulmonary epithelia and our observations strongly suggest that LCs

85 genetic processes in plant leaves and animal epithelia and perhaps even the formation of human finger

86 riants expressed beyond the proximal tubular epithelia and potential limitations of pH correction by

87 chitosan MPs delivered protein to intestinal epithelia and reduced clinical and histological scores o

88 efect in mucosal barrier function of colonic epithelia and secretory cell lineages, EP4 cKO colon str

89 activity and ASC-speck release in monocytes, epithelia and serum with CF-associated mutations; these

90 mechanical differences between those sensory epithelia and their supporting cells prompted us to inve

91 Upon replication in mucosal epithelia and transmission to nerve endings, capsids of

92 ity among tuft cells that extends from nasal epithelia and type II taste cells to ex-Aire-expressing

93 in fibers seen in normal lung between airway epithelia and underlying smooth muscle cells was missing

94 s talk of innate lymphoid cells with damaged epithelia and with the recipient microbiome, the impact

95 um is disrupted (e.g. wounded skin/bronchial epithelia) and where T cells frequently are present.

96 le excitability, electrolyte movement across epithelia, and acidification of intracellular organelles

97 expressed in adult tissue stem cells of many epithelia, and its overexpression is negatively correlat

98 trolling ion absorption and secretion across epithelia, and maintaining intracellular chloride homeos

99 ifferentiation of both CRSwNP and control-NM epithelia, and notably, we have demonstrated for the fir

100 logical niche that coats all non-keratinized epithelia, and plays a critical role in protecting the h

101 Papillomaviruses infect stratified squamous epithelia, and the viral life cycle is linked to epithel

102 In WT epithelia, antimicrobial defence and cellular stress res

103 Tubular epithelia are a basic building block of organs and a com

104 ining and straight contact phenotype seen in epithelia are also successfully quantified (i.e. cardiom

105 Epithelia are an eminent tissue type and a common driver

106 Our results demonstrate that epithelia are capable of mounting molecularly distinct r

107 Self-renewal epidermoid epithelia are continuously exposed to mutagens and are t

108 examples collectively suggest that the oral epithelia are equipped with a dynamically robust and int

109 Epithelia are exposed to diverse types of stress and dam

110 dual channels on the surface when intestinal epithelia are exposed to glucocorticoids at birth.

111 Stem cells in stratified epithelia are generally believed to adhere to a non-hier

112 ng to investigate whether airway neurons and epithelia are involved in HTS treatment-triggered ASL se

113 Areas of a junction between two types of epithelia are known to be cancer-prone in many organ sys

114 The expanded epithelia are Sox9-, Pitx2-, and Tbx1-positive cells, wh

115 Epithelia are structurally integral elements in the fabr

116 -rare solitary chemosensory cells in mucosal epithelia-are undergoing intense scientific scrutiny fue

117 Using mouse incisor tooth epithelia as a model, we show that ciliary dynamics in s

118 clinical disease, highlighting the spread to epithelia as an attractive target for therapeutic strate

119 activity that was localized primarily to the epithelia as noted by CCNB1 and Ki67 staining.

120 the scaffold USH1G that operates in sensory epithelia as part of the Usher complex, lacks the inhere

121 eveloped adroit strategies to 1) exploit the epithelia as privileged growth niches and 2) chronically

122 VAX therapy induced IDO1 expression on tumor epithelia as well as vaccine-induced tertiary lymphoid a

123 lopmental pathways in RT compared to TB oral epithelia, as well as a repertoire of genome paralogues

124 fer of material between epithelial cells and epithelia-associated dendritic cells was not limited to

125 wn about the dynamics of bacterial spread in epithelia at a population level.

126 vates the multipotency of BSCs from multiple epithelia both in vivo in mice and in vitro in organoids

127 predominant SENP transcript in human mammary epithelia but is significantly reduced in precancerous d

128 a barrier to infiltration of the underlying epithelia by both the normal microbiota and enteric path

129 Analysis of isolated tubular epithelia by FACS from bigenic SLC34a1-CreERt2; R26tdTom

130 th can have the opposite effect on wild-type epithelia by inducing, via a non-autonomous IL-1beta-dri

131 tion with CFTR in CF human primary bronchial epithelia by proximity ligation assay, immunoprecipitati

132 , we show that the replacement of the larval epithelia by the adult one in Drosophila demands the coo

133 cells within it that resemble ocular-surface epithelia can be isolated by pipetting and FACS sorting

134 Epithelia can eliminate apoptotic cells by apical extrus

135 Water and solute transport across epithelia can occur via the transcellular or paracellula

136 ia present on the surface of a multiciliated epithelia cell beat coordinately to protect the epitheli

137 m flagellar 1, or CLAMP, in human intestinal epithelia cells (IECs).

138 s compared with normal cells-ovarian surface epithelia cells and fallopian tube secretory epithelial

139 hat the TACSTD2(high) human prostate luminal epithelia cells highly express SOX2 and are relatively e

140 the barrier surface, highlighting an immune-epithelia circuitry that facilitates host-microbe symbio

141 20-1 with reduced p120-3, whereas most other epithelia co-expressed p120-3 and p120-1, including bron

142 nd maxillary processes into contact, and the epithelia co-mingle, remodel and clear from the fusion s

143 Modeling these interactions in larval epithelia confirms that Tai kills neighboring cells via

144 Airway epithelia control the pH of airway surface liquid (ASL),

145 knock out the oncogene p53 in dog oviductal epithelia cultured in a dynamic microfluidic chip to cre

146 ogether, our findings suggest that expanding epithelia decouple their internal and edge regions, whic

147 manifest reduced nuclear disruption of lung epithelia, decreased neutrophil recruitment into infecte

148 Thus, epithelia-derived signals maintain skin-resident ILCs th

149 Many glandular epithelia develop from multipotent basal stem cells (BSC

150 ncluding thinning of the seminiferous tubule epithelia, dilation of the rete testes, sperm agglutinat

151 d differentiated into multilayer ureter-like epithelia displaying robust expression of the urothelial

152 ge scale forces that can extensively remodel epithelia driving tissue buckling, closure and extension

153 ular source of newly regenerated endometrial epithelia during a mouse estrous cycle or a human menstr

154 mote actomyosin intercellular attachments in epithelia during Drosophila melanogaster mesoderm invagi

155 a de novo contribution to luminal and basal epithelia during mammary morphogenesis.

156 ssible role for in-plane stresses in shaping epithelia during morphogenesis.

157 nt and tumor-distant normal-appearing airway epithelia exhibit somatic driver alterations that underg

158 ((Epid)Casr(-/-)) mice, whose shortened neo-epithelia exhibited declined E-cadherin expression and d

159 ileum Peyer's patch (PP) follicle-associated epithelia (FAE) to limit entry points for STm invasion.

160 se-relevant cell types, including esophageal epithelia, fibroblasts, and immune cells, with some expr

161 pithelia (PSE) are a common type of columnar epithelia found in a wealth of embryonic and adult tissu

162 ind-like (dnMaml) peptide in the nephrogenic epithelia from after the s-shaped body formation and in

163 nd Bcl-2 were increased in the VDR-deficient epithelia from mice.

164 erial activity in primary cultures of airway epithelia from people with cystic fibrosis caused by dif

165 airway surface liquid pH in cultured airway epithelia from people with cystic fibrosis.

166 multipotent differentiation to the specific epithelia from which the sample originated.

167 above and below progenitors of multilayered epithelia-function to shape premalignant tumour architec

168 ze the diversity of viruses in oropharyngeal epithelia, germinal centers, probang samples (oropharyng

169 he presence of a cell that can populate both epithelia had been proposed previously but has remained

170 cts well-differentiated primary human airway epithelia (HAE) in vitro In human embryonic kidney HEK29

171 surface of well-differentiated human airway epithelia (HAE).

172 nt vertebrates continues to require external epithelia has not been addressed so far.

173 Corneal epithelia have limited self-renewal and therefore repara

174 ated after the epidermis and digestive tract epithelia have matured, ensuring that both organs can wi

175 t, functions for Pax2 or Pax8 in adult renal epithelia have not been established.

176 x internal organs and a number of studies of epithelia have outlined a general view of tissue interna

177 ense protein expressed in the nasopharyngeal epithelia; however, its role in invasive infections is u

178 mechanism that can elongate edgeless tubular epithelia in a process distinct from those that elongate

179 ining bile ducts, were cultured as polarized epithelia in a Transwell system as a model with which to

180 the contributions of the corneal and limbal epithelia in angiogenic and lymphangiogenic privilege, w

181 cardiac and skeletal muscle, liver, kidney, epithelia in general, and the narrow extracellular space

182 xpression was higher compared to surrounding epithelia in indolent samples but lower in aggressive LS

183 ctility may control fusion and separation of epithelia in many other contexts.

184 ural plate cells adopt strategies typical of epithelia in order to constrict their dorsal surface mem

185 A slimy, hydrated mucus gel lines all wet epithelia in the human body, including the eyes, lungs,

186 elial Na(+) channel (ENaC) in salt-absorbing epithelia in the kidney, lung, and other tissues.

187 rofile of IL-13-exposed primary human airway epithelia in vitro and asthmatic airway epithelia in viv

188 ic lifestyle, reducing cytotoxicity to human epithelia in vitro and attenuating infection in a porcin

189 of Yap5SA in the postnatal inner ear sensory epithelia in vivo drives cell cycle reentry after hair c

190 noids and in APC-deficient murine intestinal epithelia in vivo.

191 rway epithelia in vitro and asthmatic airway epithelia in vivo.

192 a critical defence from pathogens at mucosal epithelia including the female reproductive tract (FRT).

193 rstanding of the biology of the crb genes in epithelia, including retinal neuroepithelium.

194 l (ENaC) mediates Na(+) transport in several epithelia, including the aldosterone-sensitive distal ne

195 Glandular epithelia, including the mammary and prostate glands, ar

196 nderlying disease progression on all mucosal epithelia, including those in the mouth, lungs, and gut.

197 nd cell divisions that occur concurrently in epithelia influence tissue shape is less understood.

198 We further show that in corneal epithelia, INSR interacts with the voltage-dependent ani

199 folding is a fundamental process that shapes epithelia into complex 3D organs.

200 IGNIFICANCE STATEMENT Apicobasal polarity of epithelia is an important property that underlies the mo

201 dicating that expression in immune cells and epithelia is divided among families.

202 20) suggests that mutant p53 activity in gut epithelia is influenced by local production of microbial

203 ositioning of folds in complex, multi-folded epithelia is less well-understood.

204 sence of apical TGF-beta signaling in normal epithelia is primarily a reflection of domain-specific r

205 Intriguingly, the sessile epithelia is prone to apoptotic cell extrusion upon crow

206 In particular, bending of epithelia is thought to result from active torques gener

207 The protective role of these epithelia is, in part, dependent on a remarkable capacit

208 much is known about how cells separate from epithelia, it remains unclear how cells disperse from cl

209 NBCe1-A is expressed in proximal tubule epithelia; its dysfunction causes the plasma bicarbonate

210 roptic bronchoscopy of trachea, large airway epithelia (LAE), and small airway epithelia (SAE) of non

211 AT2 cells and other distal lung epithelia, like all eukaryotic cells, contain an elegant

212 Secondary epithelia, like the FE, have been proposed to require ad

213 ered PAR-2 polarization in disease-remodeled epithelia may enhance apical responses and increase sens

214 further promoted mtDNA secretion in cultured epithelia, mice, and PCa patients.

215 thma-associated methylation changes in nasal epithelia of adult white asthmatic patients.

216 vates YAP in supporting cells within balance epithelia of chickens, but not mice.

217 ubsequent pro-apoptotic signaling in tubular epithelia of cisplatin-treated mice, leading to marked m

218 , alongside renal tubules comprising tubular epithelia of different nephron segments.

219 topic deformations in the dorsal and ventral epithelia of Drosophila embryos.

220 s, ECD during morphogenesis in the heminotal epithelia of Drosophila pupae leading to thorax closure

221 Coexpression of EZH2(T416D) in mammary epithelia of HER2/Neu transgenic mice reprograms HER2-dr

222 the production of digestive and respiratory epithelia of histo-blood group antigens involved in the

223 d fluconazole's effects on water flow across epithelia of isolated mouse collecting ducts and on urin

224 -negative bacterium that infects the gastric epithelia of its human host.

225 c protein reliance in the vestibular sensory epithelia of mammals to the maculae of zebrafish.

226 RNP achieves editing of loxP sites in airway epithelia of ROSA(mT/mG) mice.

227 r muscle complex, nonpigmented and pigmented epithelia of the ciliary body, lens epithelium, and a su

228 Here we investigated how epithelia of the Drosophila wing disc respond to loss of

229 ns of lesion growth were observed in tubular epithelia of the liver and lung; this finding identifies

230 chemosensory cells scattered throughout the epithelia of the respiratory and alimentary tract.

231 ontribution of the nervous system and airway epithelia on HTS-stimulated ASL height increase in CF an

232 n CCA, including those targeted to the tumor epithelia (oncogenic, developmental, metabolic, epigenom

233 ltaT cells focuses on the skin and intestine epithelia, our knowledge on these cells in the gingiva i

234 t the basal level of NO in the normal breast epithelia plays crucial roles in tissue homeostasis, whe

235 s expressed in post-natal corneal and limbal epithelia progenitors (LEPC) but not in underlying strom

236 Pseudostratified epithelia (PSE) are a common type of columnar epithelia

237 in Results: The bioelectric phenotype of the epithelia recapitulates the expected absence of CFTR act

238 opment and maintenance of healthy stratified epithelia require the coordination of complex transcript

239 Quantification of junctions of mammalian epithelia requires laborious manual measurements that ar

240 The immune functions of epithelia-resident dendritic cells are influenced by epi

241 Ectopic expression of Akap12 in renal epithelia results in abnormally long primary cilia simil

242 1 and 2 (Lats1/2PanKO) from mouse progenitor epithelia results in failure to differentiate key pancre

243 rge airway epithelia (LAE), and small airway epithelia (SAE) of nonsmokers and smokers were analyzed

244 the human airway epithelium.Methods: Airway epithelia sampled by fiberoptic bronchoscopy of trachea,

245 rons and the subsequent activation of active epithelia secretion; osmosis accounts for only ~50% of t

246 Interestingly, EP4-deficient colon epithelia showed a higher number of apoptotic cells.

247 mined dendrites and glia that develop within epithelia, similar to mammalian sense organs.

248 dy, we have found that K14-Cre-mediated skin epithelia-specific deletion of Lgr4 results in delayed a

249 encodes a mammalian-specific and stratified epithelia-specific protease important in processing of f

250 In the inner ear sensory epithelia, stereociliary hair bundles atop sensory hair

251 ll-cell junctions of simple gastrointestinal epithelia such as colon and stomach, and the acini of sa

252 The development of mechanosensory epithelia, such as those of the auditory and vestibular

253 an comparisons of different pseudostratified epithelia suggest global tissue architecture may influen

254 elial T lymphocytes, which migrate along the epithelia, support epithelial homeostasis, and protect f

255 el functions for Pax proteins in adult renal epithelia that are essential for retaining water and con

256 are derived from Pax2-positive ureteric bud epithelia that continue to express Pax2 and Pax8 in adul

257 Here, we highlight four branched epithelia that develop at different spatial scales, with

258 licular epidermal, mammary and hair follicle epithelia that genotoxicity does not promote apoptosis b

259 ral regions of vestibular semicircular canal epithelia, the [K(+) ] in the synaptic cleft ([K(+) ](c)

260 outside world, some neurons protrude across epithelia, the cellular barriers that line every surface

261 ic transformation or apoptosis occurs within epithelia, the harmful or dead cells are apically extrud

262 ts membrane-bound mucins on the mosquito gut epithelia, thereby enhancing viral dissemination.

263 ffects, whereas IFN-lambda mainly signals in epithelia, thereby inducing localized antiviral immunity

264 DLRs in adult humans are considered inactive epithelia, thought to possess limited capacity for furth

265 stimulate active secretion of ASL by airway epithelia through the activation of sensory neurons.

266 ne anion channel that is widely expressed in epithelia throughout the body.

267 the vestibular ganglion away from nonsensory epithelia, thus channeling them into the sensory domains

268 ells in the renal tubules), lungs (bronchial epithelia), thymus (epithelial cells inside the Hassall'

269 he inhibition of C3a receptor sensitized PCa epithelia to docetaxel in a synergistic manner.

270 al coherence of cell layers is essential for epithelia to function as tissue barriers and to control

271 ilar competency of endodermal and ectodermal epithelia to generate all endocrine cell types.

272 any S. epidermidis isolates stimulated nasal epithelia to produce antimicrobial peptides, killing pat

273 o-inflammatory chemokine responses of airway epithelia to rhinovirus and viral mimics and decreased n

274 functionally distinct luminal and glandular epithelia, to maintain uterine cycling.

275 f blood cells (hemocytes) at the respiratory epithelia (tracheal air sacs) of the thorax and head.

276 In epithelia, tricellular vertices are emerging as importan

277 During development, intestinal epithelia undergo dramatic morphogenesis mediated by mes

278 -pathogen interactions with human intestinal epithelia using enteroid monolayers on permeable support

279 icity and permeation of IOCs across cultured epithelia using ultra-high-performance liquid chromatogr

280 expressed widely mammalian cells, including epithelia, vascular smooth muscle tissue, electrically e

281 tore host defences in cystic fibrosis airway epithelia via a mechanism that is independent of CFTR an

282 specialized progenitor cells emanating from epithelia via epithelial-to-mesenchymal transition (EMT)

283 P(Cl) /P(Na) of airway epithelia was unaltered by pH 7.4 vs.

284 Because SGG may correlate with impaired gut epithelia, we assessed the association of antibodies to

285 stituted Caco-2 cysts as proxy for polarized epithelia, we provide evidence for coordinated action of

286 terious effects were observed when bronchial epithelia were exposed to cysteamine plus the antioxidan

287 Postulating that Sdk may have a role in epithelia where AJs are actively remodelled, we analysed

288 e kidney proximal tubule and collecting duct epithelia, where it has an important role in amino acid

289 localizes to the apical surface of multiple epithelia, where it participates in endocytosis of a var

290 In pseudostratified epithelia, where nuclei are staggered across the tissue,

291 (CEACAMs) on the surface of small intestinal epithelia, where they serve as critical bacterial recept

292 the permanent renewal and reorganization of epithelia, which forms or lines many tissues and organs

293 ntly smaller auditory and vestibular sensory epithelia, while conditional overexpression of a constit

294 Multiciliated cells (MCCs) are specialized epithelia with apical bundles of motile cilia that direc

295 Tumor models of human PCa epithelia with CAF expanded similarly in mice in the pre

296 Treating epithelia with IL-17 plus TNFalpha alkalinized ASL pH to

297 05(+) fibroblasts were found to circumscribe epithelia with neuroendocrine differentiation.

298 se characterized by dysfunction of secretory epithelia with only palliative therapy.

299 pecialized regions of the vestibular sensory epithelia with specific functions in detecting head moti

300 critical for the homeostasis of transporting epithelia, yet mechanisms that control the assembly and