ライフサイエンスコーパス: equilibrium constant

1 provides an experimental measurement of the equilibrium constant.

2 at the necessary ratio to create the desired equilibrium constant.

3 he two states influences the C<-->O "gating" equilibrium constant.

4 produce a relatively weak dependence in the equilibrium constant.

5 cal temperature is defined by the 'reaction' equilibrium constant.

6 nalysis of the temperature dependence of the equilibrium constant.

7 imately 3.2) but had almost no effect on the equilibrium constant.

8 uilibria from the pressure dependence of the equilibrium constant.

9 T and yielded a pH-dependent oligomerization equilibrium constant.

10 d binds in the groove with an unusually high equilibrium constant.

11 spholipid bilayer and determined its binding equilibrium constant.

12 tent with the low dimer-monomer dissociation equilibrium constant.

13 ) having mutations that increased the gating equilibrium constant.

14 orage, and sulphur dioxide-aldehyde apparent equilibrium constants.

15 isotope, seven rate constants in all and two equilibrium constants.

16 ss for which we have determined the rate and equilibrium constants.

17 tion of predictive relationships for unified equilibrium constants.

18 of mouse neuromuscular AChR gating rate and equilibrium constants.

19 a consequence of altering the thermodynamic equilibrium constants.

20 MR technique in precisely measuring relative equilibrium constants.

21 iation of ApoE and are in agreement with the equilibrium constants.

22 n of separation conditions and estimation of equilibrium constants.

23 free energy and impacting reaction rate and equilibrium constants.

24 from the water virial equation of state and equilibrium constants.

25 The monomer-dimer equilibrium constant (~20 mum) and the CXCR2 binding con

26 ombination of the unbinding kinetics and the equilibrium constant allows the binding rate of a peptid

27 the strong adsorption sites and 24% for the equilibrium constant and 5% for the saturation capacity

28 s of the isotherm parameters were 5% for the equilibrium constant and 9% for the saturation capacity

29 cterized by a very high value of the partial equilibrium constant and large positive changes in the a

30 Equilibrium constant and photostationary state measureme

31 rg(3') in the alpha-subunit alter the gating equilibrium constant and reduce channel expression.

32 reas supramolecular crosslinks depend on the equilibrium constant and relative concentrations of cros

33 y 10 A from the Cd(2+) site affects both the equilibrium constant and the residence time of water, wh

34 action amplitudes confirm a strain-invariant equilibrium constant and thus a strain-insensitive ratio

35 le to recover both experimentally determined equilibrium constants and association/dissociation rates

36 nge (REX) protocol are applied to obtain the equilibrium constants and atomic details of the ionizati

37 the same reaction in free solution, and the equilibrium constants and dissociation and association r

38 anol dehydration are used to obtain rate and equilibrium constants and energies for intermediates and

39 ndom errors on the accuracy and precision of equilibrium constants and enthalpy changes determined by

40 lorimeters for simultaneous determination of equilibrium constants and enthalpy changes, for determin

41 s of complex I and complex II, pH effects on equilibrium constants and enzyme kinetics, and the acid-

42 ectrum, allowing the direct determination of equilibrium constants and free energy differences.

43 a unique capability to define thermodynamic equilibrium constants and kinetic rate constants for com

44 incomplete definitions of ligand binding and equilibrium constants and neglect of the non-ideality of

45 opped flow kinetics were used to measure the equilibrium constants and rates of nucleotide binding an

46 vis spectrophotometry afforded derivation of equilibrium constants and reaction enthalpies.

47 tration dependence and allows extracting the equilibrium constants and spectra of the distinct specie

48 neously extracting both the hydrogen-bonding equilibrium constants and the rate constants for the PCE

49 Comparison of the equilibrium constants and thermodynamic parameters Delta

50 The determination of equilibrium constants and thermodynamic properties of th

51 ations to alanine reduce the liganded-gating equilibrium constant, and solved the crystal structures

52 al effects on activation energy barriers and equilibrium constants, and DFT-derived parameters used t

53 et, restored normal O2 dissociation rate and equilibrium constants, and reduced O2-alphaHb autooxidat

54 The measured equilibrium constants, and the determined pK(a) and E(1/

55 The monomer/dimer equilibrium constants are between K(dim) = 10(5) M(-1) a

56 These equilibrium constants are consistent with the solution b

57 Equilibrium constants are determined, and the free energ

58 Gating rate and equilibrium constants are estimated for seven different

59 he molecular basis of such phenomena is that equilibrium constants are generally measured in three-di

60 and unfolding rate constants and the overall equilibrium constant as probes of surface area changes i

61 his regime include the potential for gaining equilibrium constants as well as rate constants, and for

62 ha-epsilon; therefore, the diliganded gating equilibrium constant at -100 mV is comparable for both r

63 The Phax left arrow over right arrow Pheq equilibrium constants at 103 K are 2.21 for 1 and 4.59 f

64 mine to the carbamic acid formation rate and equilibrium constants at 25.0 degrees C has been establi

65 the rotational diffusion does not change the equilibrium constants, but significantly affects the dyn

66 nd 80% (stem) and increased the dissociation equilibrium constant by 1.8-fold as determined by surfac

67 This ratio is then used with equilibrium constants calculated for the specific pressu

68 We show that the ratio between the 2D and 3D equilibrium constants can be expressed as a product of i

69 The measured equilibrium constants can be expressed by the sum of two

70 (c) Unified equilibrium constants can be extracted if total site dep

71 icted fold-increase in the diliganded gating equilibrium constant caused by each mutation alone.

72 ass drug (S-warfarin) and had activities and equilibrium constants comparable to those for soluble HS

73 use of simulations can lead to estimates of equilibrium constant corrections due to complex dissocia

74 predictions based on independently measured equilibrium constants corroborate experimental data of s

75 Deterpmination of equilibrium constants describing chemical reactions in t

76 s shown that a temperature jump perturbs the equilibrium constant directly to increase tension.

77 We estimated the monoliganded gating equilibrium constant E(1) and the energy change associat

78 stant only by changing the unliganded gating equilibrium constant (E(0)) and did not alter the energy

79 different constructs, the unliganded gating equilibrium constant (E(0)) was correlated with the prod

80 we measured changes in the diliganded gating equilibrium constant (E(2)) consequent to mutations of r

81 s were quantified: 1), the diliganded gating equilibrium constant (E(2)), which reflects the energy d

82 Knowing both the di- and unliganded gating equilibrium constants (E(2) and E(0)) is a foundation fo

83 uilibrium, cyclic energy delivery than under equilibrium constant energy conditions were identified.

84 d for determining accurate electron-transfer equilibrium constants even when dimer radical cations ar

85 Mutarotation equilibrium constants favored the alpha anomer over the

86 switching thermodynamics; while a switching equilibrium constant favoring the nonbinding, nonsignali

87 Gibbs free energy, the keto-enol tautomeric equilibrium constant for 2,3-dihydroxycycloprop-2-en-1-o

88 The equilibrium constant for 2a + ArOH <==> 1a + ArO(*) is (

89 nstant for Abeta degradation by CatB and the equilibrium constant for binding of CysC to Abeta were d

90 trated with pH consistent with the change in equilibrium constant for denaturation.

91 In contrast, both the rate constant and equilibrium constant for DNA opening (I(1) to I(2)) are

92 highly favorable, and we calculate that the equilibrium constant for flipping is approximately 1300.

93 e mutant protein retained a highly favorable equilibrium constant for flipping the 1,N(6)-ethenoadeni

94 he bilayer/solution interface that alter the equilibrium constant for gA channel formation, and thus

95 d 2.3 x 10(-2) s(-1), respectively, with the equilibrium constant for hybridization as 4.2 x 10(6) M(

96 ge effects of [urea] and [salt] on K(3) (the equilibrium constant for I(2) is in equilibrium with RP(

97 The equilibrium constant for intramolecular docking is obtai

98 nsitive PFL-AE to determine the kinetics and equilibrium constant for its interaction with PFL.

99 easurements showing that the drug shifts the equilibrium constant for myosin-catalyzed ATP hydrolysis

100 airpin motifs do produce enhancements in the equilibrium constant for nucleation in aggregation react

101 greater than 5 x 10(9)-fold increase in the equilibrium constant for proton transfer from C-6, so th

102 -3 positions decreased the forward rate and equilibrium constant for reversible strand ligation by 1

103 n corresponding to 1/K(S), where K(S) is the equilibrium constant for solvation of a carboxylic acid

104 Furthermore, the equilibrium constant for the conformational change (K(2)

105 The equilibrium constant for the cross-bridge force generati

106 The equilibrium constant for the reaction was measured at pH

107 ermined to be 41.0 kcal/mol by measuring the equilibrium constant for this reaction using three diffe

108 hat allows extraction of the enantiospecific equilibrium constants for (R)- and (S)-propylene oxide a

109 ng side chain statistical data, we calculate equilibrium constants for a great number of amino acid r

110 piled an experimental data set (SWITCH10) of equilibrium constants for a series of hydrogen-bond-depe

111 g assay was used to accurately determine the equilibrium constants for AdoMet binding to PFL-AE alone

112 model is applied to calculate free energies/equilibrium constants for adsorption on the individual s

113 onse curve (CRC) is determined by underlying equilibrium constants for agonist binding and receptor c

114 Equilibrium constants for alkoxides formed by protonatio

115 conformational selection model that includes equilibrium constants for both G-quadruplex unfolding an

116 The rates (kon and koff) and equilibrium constants for both reactions were determined

117 e native and denatured states as well as the equilibrium constants for denaturation of the different

118 formation was observed in several cases and equilibrium constants for dimerization were determined.

119 ine both the dissociation rate constants and equilibrium constants for drug-protein interactions in s

120 y two different methods: first, by measuring equilibrium constants for electron exchange between the

121 the partial agonism of tryptamine; however, equilibrium constants for gating and priming were simila

122 Analysis of the kinetic data yields equilibrium constants for intramolecular loop formation

123 Comparison of the rate and equilibrium constants for LIG3 and LIG1 nevertheless rev

124 The relative equilibrium constants for ligand substitution span over

125 e to learn how to predict reaction rates and equilibrium constants for reactions involving adsorbed m

126 le process, we estimated the gating rate and equilibrium constants for receptors with point mutations

127 single-channel electrophysiology, the gating equilibrium constants for receptors with zero, one or tw

128 Theoretical calculation of both the rate and equilibrium constants for such reactions requires knowin

129 Theoretical estimates of rate and equilibrium constants for surface reactions and CO adsor

130 Equilibrium constants for the associations of 17 diaryli

131 free energy relationships based on rate and equilibrium constants for the binding of these peptides

132 The equilibrium constants for the conversion of PhXn(+) to P

133 best fit model took into account two acidity equilibrium constants for the Fe(II) complexing ligands

134 As equilibrium constants for the formation of Br(2)O and Br

135 tion relating the kinetic rate constants and equilibrium constants for the formation of carbamic acid

136 and, based on the mechanism, the kinetic and equilibrium constants for the formation of carbamic acid

137 The rate of the reversible reactions and the equilibrium constants for the formation of carbamic acid

138 Rate and equilibrium constants for the reaction between N-aryl tr

139 ation of both the kinetic rate constants and equilibrium constants for the reaction of CO(2)(aq) with

140 uctures of the key proteins and the rate and equilibrium constants for the reactions for comparison w

141 Rate and equilibrium constants for the reactions of various pheno

142 At T=298.15K the equilibrium constants for the tartrazine-BSA and HSA com

143 folding transitions and determined rate and equilibrium constants for the transitions between these

144 cities of the amino acids as measured by the equilibrium constants for transfer of their side-chains

145 rption constants for orthoclase with aqueous equilibrium constants for uranyl carbonate species indic

146 ves four recombination rate constants and an equilibrium constant, for each trace isotope, seven rate

147 les, G(z,f), as a function of z, obtained in equilibrium constant force simulations, reveal the inter

148 Equilibrium constants, forward and reverse rate constant

149 itative measurement of target engagement and equilibrium constants from experimental data.

150 f macromolecular complexes with dissociation equilibrium constants from picomolar to micromolar.

151 The equilibrium constant governing interconversion of the su

152 e on DNA by BirA is exquisitely tuned by the equilibrium constant governing its homodimerization.

153 tic data afforded estimates for the rate and equilibrium constants governing the formation of (SSB)60

154 pyryliums (Pylm) form dimers quantitatively (equilibrium constants >10(4) M(-1)), but they enter as s

155 The radical-dimer equilibrium constant has been determined to be 5.7 x 10

156 both the electron transfer and O(2) binding equilibrium constants has been determined.

157 Equilibrium constants have been determined from the sedi

158 transfer rate constants, and the adsorption equilibrium constant in the low-pressure range.

159 Equilibrium constants in Cu-based atom transfer radical

160 luding concentrations, kinetic constants and equilibrium constants in modeling and simulating complex

161 e estimates of the corresponding ion binding equilibrium constants indicate that the iodide concentra

162 The correlation of rate and equilibrium constants indicates that this effect has a t

163 nformation; (iv) the ACh-monoliganded gating equilibrium constant is approximately 1.7 x 10(-3); (v)

164 The logarithm of the equilibrium constant is plotted versus inverse temperatu

165 The unliganded gating equilibrium constant is smaller and less voltage-depende

166 Despite these changes in rate, the equilibrium constant is strain-insensitive.

167 ge of their hydrolysis and corresponding low equilibrium constants, it is unlikely that these species

168 approximately +28 kcal/mol at 200 degrees C, equilibrium constant K approximately 10(-13)).

169 break up, we also use these to calculate the equilibrium constant K associated with the monomer-dimer

170 (12)C(16)O(2) isotopologue ratios allows the equilibrium constant K of the isotope exchange reaction

171 PPA imprinted polymers bound PPA with an equilibrium constant K(eq) = 1.8 x 10(5) M(-1) in aceton

172 The resulting set of equilibrium constants K(I) covers 6 orders of magnitude

173 detector, imposing a problem for finding the equilibrium constant ( K(d)) and rate constant ( k(off))

174 We measured the equilibrium constant (K = 1264 M(-1) at 294 K) and, from

175 ees C: saturable binding with an association equilibrium constant (K(a)) of 1.1-1.9x10(5)M(-1) and no

176 nstants (k(a) and k(d)) and the dissociation equilibrium constant (K(D)) of smGN for calmodulin were

177 ree monomers, as defined by the dissociation equilibrium constant (K(D)), is required for the buildup

178 step (M.T M.D.P) is slow (12 s(-1)) and the equilibrium constant (K(H)) of 1 suggests significant re

179 ation effects, stoichiometric ratio (n), the equilibrium constant (K) and thermodynamic parameters (D

180 rystals and octylamine ligands, the chemical equilibrium constant (K) of the CdSe-amine nanocrystal-l

181 Characteristic equilibrium constant (K), change of entropy (DeltaS), an

182 e characterized by computations, 1:1 binding equilibrium constants (K(1:1)) with a UV-vis active sens

183 yed saturation kinetics with similar binding equilibrium constants (K(bind)) for each.

184 s are also carried out to obtain the binding equilibrium constants (K) of ligand-quadruplex interacti

185 The association equilibrium constants (K) were determined from NMR compe

186 ly detectable consistent with the determined equilibrium constant, K(1), of (1.9 +/- 0.4) x 10(-11) M

187 )H NMR spectra, were used in determining the equilibrium constant, K(298 K) = [Rh-OCH(3)(CH(3)OH)][Rh

188 h for simultaneous determination of both the equilibrium constant, K(d), and the unknown concentratio

189 We measured the equilibrium constant, K(eq), for the formation of X@1.

190 spheric observations have suggested that the equilibrium constant, K(eq), governing the balance betwe

191 e relative humidity, were used to obtain the equilibrium constant, K(P), for the water-mediated hydra

192 The four equilibrium constants, K(1) = (5 +/- 5) x 10(7) M(-1), K

193 airs offers access to a large set of binding equilibrium constants, K(eq), that span ~6 orders and di

194 Keto-enol equilibrium constants, K(T), at 25 degrees C were obtain

195 ine, forming and reaching pseudoequilibrium (equilibrium constant K1 = 1.87 x 10(3) M(-1)) with the c

196 eptor aggregation model when the aggregation equilibrium constant (Ka) was positive and greater than

197 data were used to determine the association equilibrium constants (Ka) or global affinities (nKa') a

198 nges in kint or by changes in the adsorption equilibrium constant (Kads-H+).

199 lack of sensitivity due to high dissociation equilibrium constant KD and non-specificity due to an ab

200 Equilibrium constant (KD) and maximum binding capacity o

201 Equilibrium constant (KD), maximum binding capacity (Rma

202 ceptor concentration (Bmax) and dissociation equilibrium constant (Kd).

203 Differences in the equilibrium constants Kdimer for early and late metals e

204 gy and thus >60-fold increase in the folding equilibrium constant (Keq) for excluded volume fractions

205 Thus, the equilibrium constant (Keq) increases by approximately 16

206 59W-Leuko-PNP has an on-enzyme thermodynamic equilibrium constant (Keq) near unity in the temperature

207 Differences in the equilibrium constants (Keq ) for early and late metals e

208 However, the estimated equilibrium constants (Keq) for U-V bearing minerals wer

209 by Freundlich isotherm model with adsorption equilibrium constant (KF) of 1.46 mL g(-1).

210 Plots of log k(2) versus the corresponding equilibrium constants (log K) or Bronsted basicities (pK

211 267 conformational equilibrium constants measured across eleven solvents we

212 ciples that determine the values of rate and equilibrium constants measured by this system, using the

213 To this end, we used biochemical rate and equilibrium constant measurements as well as cryo-electr

214 mplete ET at ambient temperature but with an equilibrium constant near unity at 5 degrees C.

215 The values for the oxygen binding equilibrium constant obtained from the Michaelis-Menten

216 The ATRP equilibrium constants obtained vary over 7 orders of mag

217 Thus, our results demonstrate that the equilibrium constant of a pre-existing conformational eq

218 The equilibrium constant of a reaction with thermodynamics c

219 is in fast exchange (<milliseconds) with an equilibrium constant of about 1 mM.

220 The "gating" equilibrium constant of acetylcholine receptor-channels

221 ure on the mobile phase viscosity and on the equilibrium constant of analytes, the band velocity is n

222 79N and DeltaK210 were associated with a K2 (equilibrium constant of cross-bridge detachment step) si

223 spectrophotometry to obtain the association equilibrium constant of each complex and the quantum yie

224 K0 (ADP association constant) and larger K4 (equilibrium constant of force generation step) relative

225 ctrometry is used extensively to measure the equilibrium constant of noncovalent complexes.

226 In this report, we demonstrate that the equilibrium constant of reaction of MGO with thiols is ~

227 The dissociation equilibrium constant of the beta-clamp is of the order o

228 n forces recapitulate a higher stability and equilibrium constant of the fibril-forming peptide, simi

229 The net folding rate is a product of the equilibrium constant of the highest-energy species and a

230 The equilibrium constant of the nicking reaction, which invo

231 n of the channel, but also by perturbing the equilibrium constant of the proton-sensing residue His37

232 on the rate of R-->R" transition, while the equilibrium constant of the T<-->R has a small effect on

233 nction constructs in vitro with dissociation equilibrium constants of 200-300 nm YaaA binds DNA with

234 complex activator, hWASp, with dissociation equilibrium constants of about 100 nM.

235 l currents and estimated the gating rate and equilibrium constants of adult mouse AChRs with mutation

236 rea of calcite, adsorption surface areas and equilibrium constants of clay minerals, and cation excha

237 Rate and equilibrium constants of formation of the 1:1 and 1:2 co

238 experimentally known proton affinities, and equilibrium constants of intermediate reactions.

239 s been used almost exclusively for obtaining equilibrium constants of intermolecular interactions.

240 , we assign an error of 1.1-1.2 log unit for equilibrium constants of several reactions leading to ha

241 these measurements we calculated all of the equilibrium constants of the "allosteric" cycle as follo

242 The equilibrium constants of the binding follow a log-normal

243 ation does not affect either the rate or the equilibrium constants of the channel opening but does sl

244 ssociation rate constants and the associated equilibrium constants of the interactions could be estim

245 min D allowed the calculation of the thermal equilibrium constants of the isomerization process.

246 wed for the estimation of exchange rates and equilibrium constants of the olefins.

247 ogress of chemical processes to the rate and equilibrium constants of the process.

248 usive mechanistic information but yields the equilibrium constants of the self-assembly process as co

249 The equilibrium constants of these processes show a linear r

250 The equilibrium constants of trans and cis dimerization of m

251 istent with the near independence of folding equilibrium constant on size.

252 ata, the dependence of the rate constant and equilibrium constant on the stall angle, as well as the

253 We examined the dependence of rate and equilibrium constants on concentration of denaturant and

254 channel block) changed the diliganded gating equilibrium constant only by changing the unliganded gat

255 A thermodynamic procedure avoiding equilibrium constants or other reaction models and not r

256 issociation kinetics and find a dimerization equilibrium constant orders of magnitude lower than prev

257 ystematically characterized the rate and the equilibrium constants pertinent to channel opening and c

258 esults in an increase in the channel-opening equilibrium constant ((Phi(-1) = k(op)/k(cl)) by a facto

259 n created taking into account the calculated equilibrium constants (pK(T)) for all tautomeric reactio

260 culating transition-state rate constants and equilibrium constants plus a phenomenological relaxation

261 Certain combinations of equilibrium constants produce the sharp critical concent

262 The ion-pair equilibrium constants ranged 10(4)-10(6) M(-1) in CH3CN

263 The reaction is reversible with equilibrium constants ranging from 1.2 to 2.

264 change is revealed by the slope of its rate-equilibrium constant relationship.

265 sity functional theory estimates of rate and equilibrium constants show that the kinetically relevant

266 ChRs were designed to have specific rate and equilibrium constants simply by adding multiple, energet

267 rimetric methods have been used to determine equilibrium constants since 1937, but no comprehensive r

268 In the present work we report the equilibrium constant, stoichiometric ratio and the therm

269 ble reaction 2H(+) + 2e(-) <--> H(2) with an equilibrium constant that is dependent on the reducing p

270 Other equilibrium constants that are not readily measurable we

271 Here we measured rate and equilibrium constants that define the interaction of Ypt

272 Here, we present an approach to measure the equilibrium constants that govern muscle activation, est

273 The equilibrium constants that were determined also showed g

274 On the basis of the water dimer equilibrium constant, the effective rate coefficient of

275 rption and desorption constants, the surface equilibrium constant, the Gibbs free energy of adsorptio

276 eltaH(o) and DeltaS(o), including the gating equilibrium constant, the strength- and temperature depe

277 s of the binding free energy (affinity), the equilibrium constants, the kinetics and the specificity

278 g is capable of determining membrane-binding equilibrium constants through the reliable counting of i

279 ll require connection of individual rate and equilibrium constants to structural changes that occur i

280 We therefore measured the rate and equilibrium constants underlying Mss116 ATP utilization

281 The measured rate and equilibrium constants vary substantially with added wate

282 tion was investigated, and the monomer-dimer equilibrium constant was determined.

283 From these values and the diliganded gating equilibrium constants, we estimate that the unliganded A

284 The activation energy, turnover number, and equilibrium constant were 16.5 kcal/mol, 406 s(-1), and

285 sites in the C8-SCX fiber and the adsorption equilibrium constant were determined to be (9.1 +/- 0.3)

286 Five equilibrium constants were deduced using sinusoidal anal

287 Equilibrium constants were determined by fluorimetry fro

288 Equilibrium constants were determined.

289 Equilibrium constants were evaluated for reactions of (t

290 ic model, the oligomer dissociation rate and equilibrium constants were seen to depend not only on mo

291 Conformational equilibrium constants were transposed onto the Hammett s

292 tally determined value for the monomer-dimer equilibrium constant, which, for wild-type EGF receptors

293 N,N-acetals) were compared with experimental equilibrium constants, which are reported here for the f

294 or O(2) reactions with CO* and CO adsorption equilibrium constants, which reflect the respective acti

295 d reason, insufficient reactivity (e.g., low equilibrium constant), why o-phthalaldehyde and possibly

296 ly the free fraction of testosterone and its equilibrium constants with both these proteins in physio

297 ing the label-free determination of rate and equilibrium constants with respect to a specific binding

298 Excellent correlations of the equilibrium constants with the Cu(II/I) redox potentials

299 a substituent parameter and the dimerization equilibrium constant, with para electron-donating substi

300 gonist-independent constants--the activation equilibrium constant without agonists (E(0)) and the aff