ライフサイエンスコーパス: equilibrium dissociation constant

1 fibronectin (Fn) with a low nanomolar K(d) (equilibrium dissociation constant).

2 e mutant, consistent with a smaller observed equilibrium dissociation constant.

3 of immobilization on the Tir-IBD/Intimin-ECD equilibrium dissociation constant.

4 form stable homodimers with a submicromolar equilibrium dissociation constant.

5 raction and yield an accurate measure of the equilibrium dissociation constant.

6 a dimer, with little apparent change in the equilibrium dissociation constant.

7 to eight of these nine residues and derived equilibrium dissociation constants.

8 complexes possessing nanomolar to picomolar equilibrium dissociation constants.

9 n exponential relationship between these two equilibrium dissociation constants.

10 force-dependent DNA intercalation rates and equilibrium dissociation constants.

11 nded DNA but not single-stranded DNA or RNA (equilibrium dissociation constant = 16 nM).

12 exists primarily as an octamer in solution (equilibrium dissociation constant 6.5x10(-5) M) and leuc

13 with an approximately 8-fold increase of the equilibrium dissociation constant and an increase in DNA

14 ing analysis were performed to calculate the equilibrium dissociation constant and further characteri

15 The method was then used to measure the equilibrium dissociation constant and offrate of a 9-mer

16 s of dansyl- and fluoresceinyl-ACPs revealed equilibrium dissociation constants and dissociation rate

17 (FRET) acceptors in determination of protein equilibrium dissociation constants and kinetic rates.

18 Significant differences between the measured equilibrium dissociation constants and kinetically deriv

19 the similarities between the SPR-determined equilibrium dissociation constants and reported dissocia

20 e binds ssDNA oligonucleotides with nM-range equilibrium dissociation constants and some sequence spe

21 k(et) values as well as significantly higher equilibrium dissociation constants and steady-state K(m)

22 ptase inhibitors known to date with a 290 pm equilibrium dissociation constant, and provide the first

23 d determination of stoichiometry of binding, equilibrium dissociation constant, and thermodynamic par

24 Equilibrium dissociation constants are approximately 2.5

25 Equilibrium dissociation constants are derived independe

26 The equilibrium dissociation constants are quite small (1-85

27 possible to simultaneously abstract multiple equilibrium dissociation constants as a function of liga

28 ultra-high-affinity bidentate reagents, with equilibrium dissociation constants as low as 97 pM: >200

29 We also determined equilibrium dissociation constants as well as demonstrat

30 ilable receptor concentration divided by the equilibrium dissociation constant]) as the outcome measu

31 egative charge at the Q/R site increased the equilibrium dissociation constant at 0 mV (Kd(0)) for sp

32 as identical to a previously reported ligand equilibrium dissociation constant at rest and after acti

33 the KIX domain of the coactivator CBP, with equilibrium dissociation constants between 515 nM and 1.

34 Specifically, we show that the equilibrium dissociation constant can be strongly affect

35 position 7 in the loop and the kinetics and equilibrium dissociation constants compared with the unm

36 st = rate constant for single turnover, KD = equilibrium dissociation constant) confirms vsr's prefer

37 (st)=rate constant for single turnover, K(D)=equilibrium dissociation constant) confirms vsr's prefer

38 d faster on-rates than RTO-PF4, and apparent equilibrium dissociation constants differed approximatel

39 The equilibrium dissociation constant for 1.3 kDa polyE bind

40 198F and epsilonD175N, by an increase in the equilibrium dissociation constant for ACh (KD) and a red

41 This allows the prediction of an equilibrium dissociation constant for all potential bind

42 retained, the K(m) for E1 decreased, and the equilibrium dissociation constant for ATP increased but

43 and we also use the arrays to determine the equilibrium dissociation constant for cholera toxin bind

44 The mean equilibrium dissociation constant for CsA (K(dCsA)) bind

45 The apparent equilibrium dissociation constant for extracellular Na(+

46 ate constant at saturation with Mn2+ and the equilibrium dissociation constant for Mn2+.

47 obic stopped-flow analyses revealed that the equilibrium dissociation constant for NADPH binding (K(d

48 actor, Sox2, decreases the exchange rate and equilibrium dissociation constant for Oct-1 > or = 5-fol

49 The apparent equilibrium dissociation constant for RcPRO1 binding to

50 The equilibrium dissociation constant for reversible binding

51 When K44 is mutated to alanine, the equilibrium dissociation constant for small unilamellar

52 Rather, the data suggest that the actual equilibrium dissociation constant for the alphaHL.

53 NR target operons, gives an estimate for the equilibrium dissociation constant for the binding of act

54 In the presence of excess chelator, the equilibrium dissociation constant for the binding of ami

55 The equilibrium dissociation constant for the binding of met

56 The equilibrium dissociation constant for the binding of pVI

57 In addition, the equilibrium dissociation constant for the binding of tSH

58 Between pH 4 and 8, the apparent equilibrium dissociation constant for the CcP(H52L)/cyan

59 However, the equilibrium dissociation constant for the enzyme in a st

60 The apparent equilibrium dissociation constant for the HER3-ECD self-

61 The apparent equilibrium dissociation constant for the inhibitor boun

62 The equilibrium dissociation constant for the interaction be

63 The equilibrium dissociation constant for the substrate was

64 The equilibrium dissociation constant for the ternary comple

65 e device was used to successfully measure an equilibrium dissociation constant for Zn(2+) and human s

66 lower-affinity (LA) and higher-affinity (HA) equilibrium dissociation constants for acetylcholine in

67 The equilibrium dissociation constants for AdoMet, AdoHcy an

68 The results showed that the bulk solution equilibrium dissociation constants for anti-biotin and a

69 The equilibrium dissociation constants for Co2+ and Ni2+ act

70 arbohydrates, and (iii) measure the solution equilibrium dissociation constants for ConA and jacalin

71 From similar experiments, the equilibrium dissociation constants for dissociation of A

72 h provided semiquantitative estimates of the equilibrium dissociation constants for dissociation of B

73 Values for the equilibrium dissociation constants for high affinity bin

74 ounds, we present a protocol for determining equilibrium dissociation constants for HSA in a high-thr

75 The kinetic rate constants and equilibrium dissociation constants for monomeric and dim

76 adly to concentrated protein solutions, with equilibrium dissociation constants for nonspecific prote

77 el retardation assay was used to measure the equilibrium dissociation constants for the binding of an

78 The equilibrium dissociation constants for the binding of AV

79 The apparent equilibrium dissociation constants for the binding of bo

80 Equilibrium dissociation constants for the binding of th

81 rmined on- and off-rate constants along with equilibrium dissociation constants for the following ana

82 We show that the equilibrium dissociation constants for the interaction o

83 fluorescence anisotropy methods to determine equilibrium dissociation constants for the interaction o

84 They bound with high affinity: equilibrium dissociation constants for the three MAbs we

85 ociation and dissociation rate constants and equilibrium dissociation constants for thrombin.aptamer

86 SPR analysis yielded equilibrium dissociation constants for TnC (plus Ca(2+))

87 ple and convenient way of directly measuring equilibrium dissociation constants for very high affinit

88 netics, with HsY430A increasing the cofactor equilibrium dissociation constant from approximately 10

89 y 800 nM and TcY435A increasing the cofactor equilibrium dissociation constant from approximately 100

90 Receptor binding sites characterized by two equilibrium dissociation constants have been identified.

91 minus of Kv4.3 is calcium-dependent, with an equilibrium dissociation constant in the apo-state of 70

92 ensity of available receptors, and K(D), the equilibrium dissociation constant in the human brain, wi

93 of monomers and dimers in solution, with an equilibrium dissociation constant in the low micromolar

94 ces inclusive of both direct repeats, has an equilibrium dissociation constant in the nanomolar range

95 on with surface plasmon resonance to measure equilibrium dissociation constants in neurotransmitter m

96 polypurine site in the supF target DNA, with equilibrium dissociation constants in the 10(-8) M range

97 strategy, the binding proteins isolated had equilibrium dissociation constants in the nanomolar to m

98 es form ion pairs in liquid ammonia, but the equilibrium dissociation constants indicate favorable in

99 We kinetically determined that the equilibrium dissociation constant is 190 nM with a disso

100 The oxygen equilibrium dissociation constant is approximately 1 nm

101 tetrachloride where the ethanol-cholesterol equilibrium dissociation constant is estimated to be 2 x

102 Furthermore, the intrinsic equilibrium dissociation constant K(1) for hGluK2, like

103 e been evolved in vitro with antigen-binding equilibrium dissociation constant K(d) = 48 fM and slowe

104 s valid over the full range of values of the equilibrium dissociation constant K(D) and the other whi

105 to one molecule of the hexon trimer with an equilibrium dissociation constant K(d)((app)) of 1.1 nm.

106 An equilibrium dissociation constant K(D)(1) of 2.6 microM

107 According to the Hill equation, the equilibrium dissociation constant K(d)between PSA and it

108 ty for the peripheral site, indicated by the equilibrium dissociation constant K(S), from the depende

109 and thrombin and VEGF, respectively, display equilibrium dissociation constants K(D) of ca. 1 pM, 100

110 +/-0.7) x 10(-)(3) s(-)(1), and a calculated equilibrium (dissociation) constant (K(d)) of 1.5 (+/-0.

111 d ratio of agonist functional potency to its equilibrium dissociation constant (K(A)) at the active s

112 eraction between 11-kDa and Grb2 that has an equilibrium dissociation constant (K(D) ) value of 18.13

113 Strongest binding, with an equilibrium dissociation constant (K(D) = 32 nM) close t

114 spectively, which corresponded to an average equilibrium dissociation constant (K(D) of 2.6+/-1.4 x 1

115 facile assay is described for measuring the equilibrium dissociation constant (K(d)) and dissociatio

116 mpetition assays were performed to determine equilibrium dissociation constant (K(d)) and half maxima

117 onnexin43 (Cx43) gap junctions increased the equilibrium dissociation constant (K(d)) and reduced the

118 D25N) that may relate to the increase in the equilibrium dissociation constant (K(d)) and the very lo

119 d by ligand-binding activity, with a similar equilibrium dissociation constant (K(d)) for [(3)H]-mibo

120 e linear regime to the other occurs near the equilibrium dissociation constant (K(d)) for dNTP bindin

121 The equilibrium dissociation constant (K(d)) for the interac

122 ed aptamers can bind to target cells with an equilibrium dissociation constant (K(d)) in the nanomola

123 There was an apparent threshold at an equilibrium dissociation constant (K(d)) of 1 x 10(-)(7)

124 100-containing lipoprotein particles with an equilibrium dissociation constant (K(D)) of 17 nm and a

125 analysis of binding studies demonstrates an equilibrium dissociation constant (K(d)) of 27.6 nm.

126 o the fibrinogen-like domain of TN-C with an equilibrium dissociation constant (K(d)) of 5 x 10(-9) m

127 and 1.15 +/- 0.08 x 10(-6) s(-1) to give an equilibrium dissociation constant (K(D)) of approximatel

128 )), dissociation rate constant (k(off)), and equilibrium dissociation constant (K(D)) of chemically d

129 eparation" (ACTIS), a method for finding the equilibrium dissociation constant (K(d)) of protein-smal

130 vestigations--that enables us to measure the equilibrium dissociation constant (K(D)) of recombinant

131 The apparent equilibrium dissociation constant (K(D)) of the vnd/NK-2

132 midinone analog, binds to the enzyme with an equilibrium dissociation constant (K(d)) of ~400 nM.

133 for AMPhe-Gly-Gly, which bound to Q7 with an equilibrium dissociation constant (K(d)) value of 0.95 n

134 tosamine (3'-SLN) and 6'-SLN sialosides with equilibrium dissociation constant (K(D)) values of 30.0

135 detected for oleic acid with a subnanomolar equilibrium dissociation constant (K(d)).

136 inhibitor of factor Xa (FXa) with a reported equilibrium dissociation constant (K(I)) of approximatel

137 Finally, equilibrium dissociation constants (K(b)) of selective a

138 o each studied antigen, we obtained apparent equilibrium dissociation constants (K(D) values) spannin

139 Equilibrium dissociation constants (K(d)'s) of the compo

140 ans [KCl] was systematically lowered and the equilibrium dissociation constants (K(d)) and kinetics o

141 us (SARS-CoV)-neutralizing antibody 80R with equilibrium dissociation constants (K(D)) as low as 37 p

142 protective antigen subunit of the toxin with equilibrium dissociation constants (K(d)) between 63 nM

143 ric studies reveal moderate decreases in the equilibrium dissociation constants (K(d)) for both ATP a

144 eparation performance allows quantitation of equilibrium dissociation constants (K(d)) for both rapid

145 Equilibrium dissociation constants (K(d)) for each coagu

146 oNT/A Lc yielded 15 yeast-displayed VHH with equilibrium dissociation constants (K(d)) from 230 to 0.

147 nity host-glycan:bacterial-glycan pairs with equilibrium dissociation constants (K(D)) ranging betwee

148 try was used to determine apparent gas-phase equilibrium dissociation constants (K(d)) values of 0.15

149 The apparent equilibrium dissociation constants (K(D)) were compared

150 Equilibrium dissociation constants (K(d)) were measured

151 on, making it possible to calculate apparent equilibrium dissociation constants (K(d)s) for NCPs reco

152 y interactions, such as SH2 and PTB domains, equilibrium dissociation constants (K(D)s) for their pep

153 A high inhibition potency (equilibrium dissociation constant [K(i)] = 2.34 +/- 2.94

154 independent of DNA sequence with an apparent equilibrium dissociation constant, K(d)((app)), of 46 nm

155 as 6-fold after replacing a single adenine (equilibrium dissociation constant, K(D), 5.3 nm) with an

156 The equilibrium dissociation constant, K(d), for the reversi

157 ent kinetic constants, k(on) and k(off), and equilibrium dissociation constant, K(d), have been deter

158 -based binding kinetic analysis indicated an equilibrium dissociation constant, K(d), of 54 nmol/L fo

159 nonspecific partitioning into the lipid, the equilibrium dissociation constant, K(d), of isoflurane b

160 The radiotracer equilibrium dissociation constant, K(D), was similar in

161 Herein, the apparent equilibrium dissociation constant, K(Dapp), between Cu(2

162 The apparent equilibrium dissociation constant, K(DApp), for the Cu(2

163 Microscopic equilibrium dissociation constants, k as, were determine

164 The affinities (equilibrium dissociation constants, K(d)) for the SAR-55

165 al binding sites on the cell surface, N, and equilibrium dissociation constants, K(nsL) and K(nsM), f

166 ) M(-1) s(-1), which correspond to acid-base equilibrium dissociation constants (Ka) in excellent agr

167 It showed an equilibrium dissociation constant (KB) of 167.3 nM with

168 sequences that can be used to calculate the equilibrium dissociation constant ( Kd ) from hybridizat

169 Equilibrium dissociation constant (KD) and maximum bindi

170 haracteristics, as indicated by the measured equilibrium dissociation constant (Kd) for the binding o

171 immunosorbent assay-type binding assay, the equilibrium dissociation constant (Kd) for the interacti

172 lated cell lines in variant patterns with an equilibrium dissociation constant (Kd) in the nanomolar

173 ERp5 binds to beta3 integrin with an equilibrium dissociation constant (KD) of 21 microM, mea

174 Quantitative analysis yields an equilibrium dissociation constant (KD) of 777 +/- 93 nM

175 Equilibrium dissociation constant (Kd) values were calcu

176 g, and this observable was used to determine equilibrium dissociation constant (Kd) values.

177 o the high-affinity binding site of TTR with equilibrium dissociation constants (Kd values) in the lo

178 f) approximately 10(-4)-10(-3) s(-1); giving equilibrium dissociation constants (Kd) = 8-50 nM.

179 ent antibodies with over a four-log range of equilibrium dissociation constants (KD) and found that S

180 sed an approximately 40-fold decrease in the equilibrium dissociation constants (Kd) for ATP from app

181 rrays of the selected sequences and obtained equilibrium dissociation constants (Kd) for every aptame

182 e protection assay was used to determine the equilibrium dissociation constants (Kd) for the binding

183 y of high-affinity protein interactions with equilibrium dissociation constants (KD) in the picomolar

184 complexes formed in a 1:1 stoichiometry with equilibrium dissociation constants (Kd) of 50 +/- 10 nM

185 , and Ab-labeled Dynabeads exhibited similar equilibrium dissociation constants (Kd), approximately 2

186 a carbohydrate-dependent affinity of rSodC (equilibrium dissociation constant [KD] = 0.862 muM) that

187 inity for Fn was very high for both FL-ScpB (equilibrium dissociation constant [KD] = 4.0 nM) and Scp

188 es obtained were V3 (receptor density [Bmax]/equilibrium dissociation constant [KD]), V3' (f1 x Bmax/

189 hesis that there are distinct high-affinity (equilibrium dissociation constant [KD], 20 microM) and l

190 67 cells revealed high-affinity LDL binding (equilibrium dissociation constant, Kd = 7 nM) and maximu

191 e literature, estimates of the monomer-dimer equilibrium dissociation constant, KD, have varied more

192 e S1 domain and bound S1 with high affinity (equilibrium dissociation constant, Kd=32.3 nM).

193 Fluorescence emission measurements of the equilibrium dissociation constants, Kd, of oxidized (hAR

194 The value of the equilibrium dissociation constant (KD1xKD2=1.64x10(-7) m

195 stent problem is that reported values of the equilibrium dissociation constants (Kds) of complexes of

196 it is optimal to use a binding moiety whose equilibrium dissociation constant matches that of the av

197 The equilibrium dissociation constant measured for LATB bind

198 Equilibrium dissociation constants measured for sequence

199 Surprisingly, equilibrium dissociation constants measured for the kina

200 Equilibrium dissociation constants obtained for the acti

201 tion of a 1:1 stoichiometric complex with an equilibrium dissociation constant of 0.2 to 0.4 micromet

202 ectively to the AChE peripheral site with an equilibrium dissociation constant of 1.0 microm.

203 transition state analogue inhibitor with an equilibrium dissociation constant of 1.0 nM.

204 loop results in a heterodimer with a subunit equilibrium dissociation constant of 1.32 +/- 1.25 micro

205 The BIACORE data show an equilibrium dissociation constant of 1.58 nM for the com

206 splayed high binding affinity to EphB4, with equilibrium dissociation constant of 1.98-23 nM.

207 plex approximately 700-fold, resulting in an equilibrium dissociation constant of 130 nM.

208 ChIP3 in a calcium-dependent manner, with an equilibrium dissociation constant of 2-5 muM in the calc

209 odimer binds to the S15-rRNA complex with an equilibrium dissociation constant of 2.7 nM at 40 degree

210 escence anisotropy and providing an apparent equilibrium dissociation constant of 236 nm.

211 e-site binding model and yielded an apparent equilibrium dissociation constant of 334 +/- 23 nm.

212 endosomal PS, and we estimated an hsc-70/PS equilibrium dissociation constant of 4.7 +/- 0.1 mum.

213 affinity of the species B1 Ad16 fiber knob (equilibrium dissociation constant of 437 nM).

214 W1 and W2 each bound to PA with an equilibrium dissociation constant of 4x10-11 mol/L to 5x

215 been immobilized on plastic with an apparent equilibrium dissociation constant of 5 nM.

216 and 14-3-3zeta is of high affinity, with an equilibrium dissociation constant of 7 nM.

217 s a reversible monomer/dimer mixture with an equilibrium dissociation constant of 8.0 +/- 2.5 microM.

218 ht-binding inhibition with TvPNP, to give an equilibrium dissociation constant of 87 pM, an inhibitor

219 single protein-RNA complex with an apparent equilibrium dissociation constant of 9.0 x 10(-6) M.

220 An equilibrium dissociation constant of 92 nM for the p66/p

221 ed by experimental data that the value of an equilibrium dissociation constant of a binding peptide c

222 = NH4(+) > Cs(+) > Na(+)); and the apparent equilibrium dissociation constant of a single regulatory

223 ent energy donor and acceptor groups gave an equilibrium dissociation constant of about 0.8 microM(2)

224 s the data in the absence of tau, yields the equilibrium dissociation constant of approximately 2 mic

225 7.2, and we estimate an upper limit for the equilibrium dissociation constant of approximately 50 nM

226 Pase Rho3p in a GTP-dependent manner with an equilibrium dissociation constant of approximately 70 mi

227 on application of a pressure of 500 bar, the equilibrium dissociation constant of BamHI binding to th

228 e variants have substantial reduction in the equilibrium dissociation constant of binding (KD) of hMP

229 n encoded in the human genome to measure the equilibrium dissociation constant of each domain for 61

230 r distortion (isomerization) showed that the equilibrium dissociation constant of RNA polymerase-P1 c

231 Even for Ca(2+), however, the apparent equilibrium dissociation constant of the cation with the

232 The equilibrium dissociation constant of the dimeric clamp v

233 The equilibrium dissociation constant of the DNA binding dom

234 k(off) by a substrate-trapping approach, the equilibrium dissociation constant of the enzyme-DNA comp

235 Equilibrium dialysis demonstrated that the equilibrium dissociation constant of the flavopiridol-DN

236 These results suggest that the equilibrium dissociation constant of the LFA-1/ICAM-1 in

237 n chemosensory perception, we determined the equilibrium dissociation constant of the OBP-pheromone c

238 The equilibrium dissociation constant of the resting conform

239 beta(4) and profilin may greatly exceed the equilibrium dissociation constant of the ternary complex

240 (SLBs), forming a PS-Zn(2+) complex with an equilibrium dissociation constant of ~100 muM.

241 ), 5.9 x 10(-3), and 1.9 x 10(-2) s(-1), and equilibrium dissociation constants of 0.72, 0.71, 0.56,

242 Eight analogues of ImmH are identified with equilibrium dissociation constants of 1 nM or below.

243 to protein A on disulfide monolayers yielded equilibrium dissociation constants of 1.4x10(-7)M.

244 s indicated that ECS binds antithrombin with equilibrium dissociation constants of 10.5 and 66 microM

245 ovalbumins in the intact form bind ANS with equilibrium dissociation constants of 116 and 125 microM

246 hat binds to mouse IgG1 and mouse IgG2a with equilibrium dissociation constants of 13.2 microM and 14

247 nfirm the 2:1 stoichiometry of binding, with equilibrium dissociation constants of 176 nM and 431 nM

248 r cytosine base at position 8 that result in equilibrium dissociation constants of 2.6 nM, 10 nM and

249 The equilibrium dissociation constants of 24B11 (KD = 4.2 x

250 omic-binding sites, we measured the in vitro equilibrium dissociation constants of 43 binding-site va

251 inus of the laminin-5 alpha(3) subunit, with equilibrium dissociation constants of 50 nm for plasmino

252 Respective equilibrium dissociation constants of 6 and 26 mM were o

253 nset, tight-binding inhibitors of MtPNP with equilibrium dissociation constants of 650, 42, and 24 pM

254 Equilibrium dissociation constants of anti-digoxin antib

255 The equilibrium dissociation constants of complexes of CRABP

256 We have measured the kinetic rates and equilibrium dissociation constants of IgG binding to a s

257 non-lamellar lipids can be characterized by equilibrium dissociation constants of tens of micromolar

258 Collectively, the equilibrium dissociation constants of the soluble forms

259 The equilibrium dissociation constants of these peptide-pept

260 el retardation technique was used to measure equilibrium dissociation constants of this polymerase fo

261 Equilibrium dissociation constants of wild-type and base

262 2A interact with 1:1 stoichiometry at a KD (equilibrium dissociation constant) of 1.5 muM.

263 ain binds to three CD46 molecules with a KD (equilibrium dissociation constant) of 15.5 nM.

264 led a complex binding mechanism with a K(D) (equilibrium dissociation constant) of 150 nM +/- 70 nM.

265 that it binds the scFv antibody with a K(D) (equilibrium dissociation constant) of 46 nM.

266 the presence of RCC1, L binds Ran with a KD (equilibrium dissociation constant) of approximately 3 nM

267 Dependence of the equilibrium dissociation constant on the ionic strength

268 The low value of equilibrium dissociation constant or affinity unit (KD)

269 To identify the alpha(2)AR subtype involved, equilibrium dissociation constants (pK(b)) were determin

270 data, which have been used to determine the equilibrium dissociation constants, point to the loss of

271 The measurements of both equilibrium dissociation constants provided us with a th

272 es of 223 unique molecular interactions with equilibrium dissociation constants ranging from 2 x 10(-

273 nge of antibody-ligand binding kinetics with equilibrium dissociation constants ranging from 200 pM t

274 okines binds EVM1 with 1:1 stoichiometry and equilibrium dissociation constants ranging from 29 pM to

275 dissociation and no measurable change in the equilibrium dissociation constant relative to that of th

276 nce-independent DNA-binding proteins with nm equilibrium dissociation constants such that in the viru

277 le binding site for betaCD, with an apparent equilibrium dissociation constant that varies by >100-fo

278 are not what one would expect based on their equilibrium dissociation constants; that the volume of a

279 nce quenches on the order of 6-15%, allowing equilibrium dissociation constants to be measured.

280 s exhibited sub-nanomolar (0.69 nM) apparent equilibrium dissociation constant toward the extracellul

281 For the peptide Tyr-Leu-Ala, the equilibrium dissociation constant value is 7.2 nM, where

282 eoyl-sn-glycero-3-phosphocholine) yielded an equilibrium dissociation constant value of Kd = 180 +/-

283 At concentrations close to their equilibrium dissociation constant values, RIN1 and RAF1

284 E62 consensus binding sequence yielded K(D) (equilibrium dissociation constant) values in the nanomol

285 The dimer equilibrium dissociation constant was 0.25 microM in 0.0

286 In each case, the equilibrium dissociation constant was determined by foll

287 The secondary equilibrium dissociation constant was found to be the mo

288 In fact, the equilibrium dissociation constant was in the femtomolar

289 s sharply decreased by 10(3)-fold, while the equilibrium dissociation constant was weakened by nearly

290 By binding competition and determination of equilibrium dissociation constants, we show that Blimp-1

291 Lower limits to moenomycin off-rates and equilibrium dissociation constants were 7.7 x 10(-)(4) s

292 These equilibrium dissociation constants were based on the obs

293 polarization assay for these six AAAEs, and equilibrium dissociation constants were determined in di

294 Low nanomolar equilibrium dissociation constants were found for the ne

295 tein associates with HLA-A and -B molecules; equilibrium dissociation constants were in the nanomolar

296 A wide range of equilibrium dissociation constants were observed, and as

297 With this technique, equilibrium dissociation constants were quantified for p

298 The estimated equilibrium dissociation constants were virtually identi

299 n of rhodopsin to 11CR and opsin has a 25-pM equilibrium dissociation constant, which corresponds to

300 ly equal to the antibody-peptide fluorophore equilibrium dissociation constant, which is near one nan