ライフサイエンスコーパス: equipotent

1 do analogues 19, 22, and 28 were found to be equipotent.

2 tripeptide 4k (Cbz-Leu-Leu-D,L-Phe-CH2F) is equipotent.

3 ition state inhibitor and contrasts with the equipotent 2',5'-dd-3'ATP, a post-transition state nonco

4 The best of these compounds were the equipotent 6-[4-(2-ethoxyethoxy)benzoyl]-2-(pent-4-yn-1-

5 At equipotent acetylcholine concentrations, alpha 3 beta 2

6 Type I inhibitor SB590885 is roughly equipotent across RAF isoforms and, as expected, type I.

7 One of these frontrunner compounds, 15, was equipotent across the two strains (K1 = 25.0 nM, NF54 =

8 whereas flagellin and TNFalpha seemed to be equipotent activators of p38 mitogen-activated protein k

9 lso found that all four EET regioisomers are equipotent activators of the K(ATP) channels, reducing t

10 er of targeted covalent EGFR inhibitors with equipotent activity across mutants EGFR and good WT-EGFR

11 r of IRAK4 kinase activity that demonstrates equipotent activity against multiple MyD88-dependent res

12 fficacious antimicrobial agents that display equipotent activity against vancomycin-sensitive and van

13 ovalent mutant-selective EGFR inhibitor with equipotent activity on both oncogenic and T790M-resistan

14 atives such as 54j and 54k which demonstrate equipotent activity versus the KDM4 (JMJD2) and KDM5 (JA

15 al agonist/antagonist profile and bound with equipotent affinity (K(i) approximately 0.5 nM) to both

16 d orally bioavailable inhibitor of CDK8 with equipotent affinity for CDK19.

17 t liver-stage malaria parasites and are also equipotent against a panel of pathogenic protozoan paras

18 nce of either 2 mug/mL AZM or 16 mug/mL AMX (equipotent against A. actinomycetemcomitans).

19 CMX410 is equipotent against drug-sensitive and drug-resistant str

20 Both enantiomers are equipotent against human cytomegalovirus (HCMV) and vari

21 is reversible; moreover, rustmicin is nearly equipotent against the solubilized enzyme.

22 Moreover, they exhibited full and equipotent agonist activity compared to GABA at GABA(A)-

23 onal P2Y2 receptors at which UTP and ATP are equipotent agonists.

24 nt respiratory depression, in contrast to an equipotent analgesic dose of morphine.

25 ile the much more lipophilic but essentially equipotent analog 8 performed poorly.

26 An equipotent analog of dolastatin 10, lacking the thiazole

27 structure-guided modification, a truncated, equipotent analogue of CTX-I, and demonstrate, using var

28 in turn enables the scalable synthesis of an equipotent analogue, Asn((N-ethylazide))-S,6'-dideoxy-a-

29 la24], [Ala25], [Ala26], and [Ala29] yielded equipotent analogues and [Ala7], [Ala12], [Ala17], [Ala2

30 oxygen by either nitrogen or sulfur yielded equipotent analogues.

31 ve to enprofylline 2b, pentoxifylline 35 was equipotent and 1-propylxanthine 3 was >13-fold more pote

32 ,3,4-tris-phosphate are full agonists, being equipotent and 23-fold less potent than Ins(1,4,5)P(3),

33 In parallel, we discovered the equipotent and equally stable hexadecylthiopropyl (HTP)

34 Because ATP and UTP appear equipotent and equieffective in regulating ion transport

35 al alkylation and side-chain lipidation, was equipotent and retained full efficacy at GIPR as the nat

36 ceiving a treatment with imidazenil in doses equipotent and with a schedule identical to that of diaz

37 blast cells are known to be developmentally equipotent and yet eventually contribute distinct sets o

38 genous analog lithocholic acid was virtually equipotent), and the most potent inverse GSM identified

39 that corneal and conjunctival epithelia are equipotent, and that identical oligopotent stem cells ar

40 selective COX-2 inhibitors in vitro, showed equipotent anti-inflammatory activity compared to the co

41 ch are distinct from bortezomib, and exhibit equipotent anti-multiple myeloma activities, are undergo

42 anticoagulated with heparin compared with an equipotent anti-Xa concentration of enoxaparin.

43 For example, compounds 4.11 and 4.13 are as equipotent as AMP with regard to FBPase inhibition.

44 via KOP receptor-mediated mechanisms, being equipotent as an analgesic to the KOP agonist U50,488.

45 methyl (15) and ethyl (16) esters are about equipotent at A1 but not at A2a receptors.

46 l substituted analogue (38c) was found to be equipotent at AMPA and GLUK5-containing kainate receptor

47 om both normal controls and CGD patients are equipotent at arresting the growth of Aspergillus conidi

48 190-fold, respectively) but were essentially equipotent at DAT and sigma(1) receptors (10; K(i) = 77

49 fect, despite the fact that both stimuli are equipotent at inducing Ig class switching and Ig secreti

50 o(4,3-b)-1,4-oxazin+ ++-9-ol (PD 128907) was equipotent at inhibiting the activity of both population

51 gth isotypes of ApoE produced in E. coli are equipotent at inhibition.

52 hate-6-azophenyl-2', 4'-disulfonic acid were equipotent at P2X(1) and P2X(1/5) receptors; however, th

53 The corresponding 5-methylphosphonate was equipotent at P2X1 receptors.

54 Several analogues were nearly equipotent at rat and human A3 receptors.

55 peritonitis in vivo, RvD1 and AT-RvD1 proved equipotent (at nanogram dosages), limiting polymorphonuc

56 upper airway epithelium is maintained by an equipotent basal progenitor cell population, in which th

57 xposure concentrations were calibrated to be equipotent based on the yeast estrogen screen (YES), whi

58 the trimethoxyphenyl moiety gave rise to an equipotent benzamide analogue M4K2149 with reduced off-t

59 Propranolol, administered at equipotent beta-blocking dosage, reduced the number of a

60 he S1 subsite pocket were found to be nearly equipotent between the human and the murine enzymes.

61 tituted benzoic acid scaffold that displayed equipotent binding to Mcl-1 and Bfl-1.

62 even-membered ring analogs are approximately equipotent, binding affinities of those having three- to

63 group of 1 resulted in the identification of equipotent (both against the enzyme and in cell culture)

64 s, and not a small subpopulation, possess an equipotent capacity to become DTPs.

65 regulates the developmental potential of two equipotent cells along the dorsoventral axis.

66 -P equivalence group' take place between the equipotent cells themselves.

67 e two different tissues from a population of equipotent cells.

68 than CXCR1, although both receptors mediated equipotent chemotaxis and exocytosis in RBL.

69 W) mutations, in the absence and presence of equipotent clinical range concentrations of etomidate, R

70 Both (R)-1 and (R)-3 are about equipotent, comparable to DOI in activity but about 10-f

71 t, suppressing global protein synthesis with equipotent concentrations of cycloheximide actually prev

72 Following incubation of cells with equipotent concentrations of IFN-alpha or IFN-lambda, Hu

73 However, equipotent concentrations of NMDA, a nontransported agon

74 cal processes were indistinguishable between equipotent concentrations of the three chemicals.

75 ranscriptome and whole proteome responses to equipotent concentrations of three agonists of the AHR,

76 after 4 h exposure to DBPs at predetermined equipotent concentrations, identified significant change

77 At equipotent concentrations, isoflurane, but not sevoflura

78 Here we show that azumolene, an equipotent dantrolene analog, inhibits a component of SO

79 cortistatinone, Delta(16)-cortistatin A (the equipotent direct precursor to cortistatin A), and its r

80 8) of the beta2-receptor were randomized to equipotent dosages of carvedilol or metoprolol for two 6

81 Similarly, i.t. co-injection of almost equipotent dosages of reactive red 2 (30 micrograms) and

82 a]pyridazine]-8'-carboxamide (BMS-591348) at equipotent doses for Ca(2+)-mobilization.

83 Isoflurane, but not sevoflurane, at equipotent doses induced cell damage determined by both

84 ough bispectral index values may differ with equipotent doses of different agents.

85 ne (control, n = 8), or with the addition of equipotent doses of epinephrine 1 microM (n = 8), dobuta

86 d primary cortical neurons were treated with equipotent doses of isoflurane and sevoflurane.

87 nduced significantly fewer side effects than equipotent doses of semaglutide.

88 We have also monitored parasite responses to equipotent doses of the clinical antimalarial inhibitors

89 Filled prescription data were converted in equipotent doses to mometasone furoate (1 mg/g).

90 -based regimens which are evaluated at human equipotent dosing in a mouse model of TB meningitis, dem

91 avitoclax to standard TB treatments at human equipotent dosing in mouse models of TB, inhibits Bcl-2

92 sms play upon the determinative machinery of equipotent early RPCs to drive clonal variability.

93 '-O-(3-thiotriphosphate) being approximately equipotent (EC(50) = 1 microM) in eliciting extracellula

94 UTP and ATP were equipotent (EC50 approximately 25 microM) in stimulating

95 Both the peptide and analogue were equipotent (ED50=0.5 microg) in significantly increasing

96 ieved only upon controlled release, where an equipotent efficacy to the free linezolid control was de

97 rmation involves the aggregation of multiple equipotent endocrine progenitors that transition from a

98 motif led to the discovery of compound 3, an equipotent enzyme inhibitor with significant improvement

99 odules with collagen results in four broadly equipotent FN-collagen interaction sites.

100 ring around the ratio at which the MAbs were equipotent for a given HIV-1 strain (on the basis of the

101 roup generated a compound, BX 511, which was equipotent for both human and mouse CCR1.

102 Our results reveal that most PARPi are equipotent for both PARPs, including the next-generation

103 + ++amin o]-4-methylpentanoic acid (22), was equipotent for ECE-1 and NEP.

104 tive binding assay and isoliquiritigenin was equipotent for ER subtypes.

105 ken with the fact that the two compounds are equipotent for inhibiting adenylyl cyclase activity, the

106 ary CD34(+) CML cells, nilotinib and IM were equipotent for inhibition of BcrAbl activity, producing

107 cs for BrAAP activity are also approximately equipotent for inhibition of the chymotrypsin-like (ChT-

108 Compound 18 was equipotent for ROCK1 (IC(50) = 650 nM) and ROCK2 (IC(50)

109 ctivation of wake-promoting systems at doses equipotent for sleep induction.

110 After erlotinib commencement, SBRT with equipotent fractionation was delivered to all sites of d

111 r molecule, were synthesized and found to be equipotent free radical scavengers in solution as assess

112 is sufficient to select a single R8 from an equipotent group of cells called the intermediate group

113 Competition binding analysis revealed equipotent, high affinity binding of NmU isopeptides to

114 Adenosine and AMP were equipotent human A(1)R agonists in our real-time assay a

115 ) and R(-) enantiomers of isoflurane are not equipotent, implying involvement of proteins.

116 inactivated state of the channel, ST-2262 is equipotent in a protocol that favors the resting state o

117 MPC-6827 was equipotent in an in vitro growth inhibition assay in sev

118 inhibitors activate p53, the inhibitors were equipotent in arresting the cell cycle in isogenic breas

119 nical development in multiple sclerosis, was equipotent in both assays (EC50 1.5 and 1.1 nM, respecti

120 Although PNLIP and PNLIPRP2 were equipotent in inducing lipolysis and lipotoxic injury, C

121 rom rat fetal cortices, BDNF and NT-4/5 were equipotent in inducing NPY production but NT-3 and NGF w

122 or aspirin-triggered LXA(4)) are essentially equipotent in inhibiting human polymorphonuclear leukocy

123 Nifedipine (30 microM) was equipotent in inhibiting the firing rate of control (51.

124 ross-linking studies showed that heparin was equipotent in inhibiting the formation of 125I-IGF-I-K13

125 comparable with human abuse levels were not equipotent in maintaining male sexual behavior patterns

126 ore importantly, compound 10 was found to be equipotent in MES-SA cells and paclitaxel-resistant, p-g

127 revealed that hypercholesterolemic DCs were equipotent in naive CD4(+) T-cell priming efficacy with

128 This potentiation is equipotent in portal vein-ligated and sham rats, immedia

129 lude that at the dosages used, ML and FP are equipotent in reducing Qaw in patients with mild asthma,

130 Methysergide and phentolamine were equipotent in reversing increases in SMR thresholds.

131 and 3'-O-(4-benzoyl)benzoyl-ATP were roughly equipotent in rising [Ca2+]i in gonadotrophs, while ADP

132 in permeabilized cells showed that InsP3 was equipotent in SH-SY5Y and AR4-2J cells but was approxima

133 All three chloro-isomers of PBG were equipotent in stimulating PI turnover.

134 The anti-CD28 dAb is equipotent in the inhibition of CD80- and CD86-mediated

135 contrast, 5,6-cis-EET and 5,6-trans-EET were equipotent in their capacity to inhibit collagen-induced

136 The two proteins proved equipotent in this assay, arguing that interaction of MI

137 cate solomonamide counterparts, demonstrates equipotent in vivo anti-inflammatory efficacy.

138 At concentrations adjusted to give equipotent increases in the cytosolic Ca(2+), both agent

139 eta3, whereas the NAMs exhibited essentially equipotent inhibition of alpha4beta2, alpha6beta2beta3,

140 t and selective MEK1/2 kinase inhibitor with equipotent inhibition of WT and mutant MEK1/2, whose dru

141 ive, cellularly active compounds that showed equipotent inhibition of WT MEK1/2 and a panel of MEK1/2

142 ose structural analogue 1031U89, which is an equipotent inhibitor of TS but is a less efficient subst

143 prothrombin fragment 1 (residues 1-155) were equipotent inhibitors of [125I]prothrombin and [125I]fac

144 s confirmed that most of these compounds are equipotent inhibitors of both human CAMKKs and isotherma

145 s in CDK4 affinity, giving ligands that were equipotent inhibitors of CDK4 and CDK2.

146 At equipotent inotropic doses and matched preload, EMD-5703

147 Because 7 and 8 are approximately equipotent, it appears that the orientation of the pepti

148 ex with one or two dimer-selective (PHI1) or equipotent (LY3009120) inhibitor(s).

149 prevention of obesity in an independent but equipotent manner to PVH(MC4R) neurons.

150 1-25, Ac-DPhe(pI)-Arg-Nal(2')-Arg-NH(2)], an equipotent MC4R antagonist to agouti-related protein [AG

151 with either Nal(2') or D-Nal(2') resulted in equipotent melanocortin receptor potency, suggesting tha

152 ty, and a prolonged half-life along with its equipotent metabolite.

153 ontrast, the S-enantiomer of propafenone, an equipotent Na channel blocker but much weaker RyR2 inhib

154 This resulted in equipotent nanomolar inhibitors of DNA gyrase from Esche

155 ly resolved a stereotypical process by which equipotent nephron progenitors generate a nephron anlage

156 amiloride with hydrochlorothiazide, at doses equipotent on blood pressure, prevents glucose intoleran

157 34c was found to be equipotent on chloroquine-sensitive and -resistant cell

158 This antibody, RB1, is equipotent on RSV A and B subtypes, potently neutralizes

159 the synthesis of several analogues that are equipotent or exceed the potency of the natural product.

160 benzimidazolones and benzimidazolinones gave equipotent or more potent analogues.

161 respectively, providing compounds that were equipotent or more potent than 1.

162 These optimized siRNAs were generally equipotent or superior to native siRNAs and exhibited in

163 entification of a number of simpler, and yet equipotent, or even more potent, antibacterial agents th

164 Results indicated that the equipotent P2Y2 receptor agonists UTP or ATP (1-100 micr

165 The FKN-K7A mutant acted as an equipotent partial agonist, whereas the FKN-R47A mutant

166 ous MaSC populations that function as single equipotent pools in the long term.

167 onstrates that intestinal stem cells form an equipotent population in which the loss of a stem cell i

168 Ryanodine (1) and dehydroryanodine (2) are equipotent probes for the ryanodine receptor (ryr) of ca

169 ay acts as a bipotential cell-fate switch on equipotent progenitor populations in other settings.

170 Following an expansion phase, equipotent progenitors transition into a phase of homeos

171 ighbours, and it is unclear how chromatin in equipotent progenitors undergoing lateral inhibition qui

172 ditis elegans somatic gonad that derive from equipotent progenitors, but exhibit distinct cell behavi

173 Comparative work with an equipotent radiolabeled MT1-MMP targeting antibody demon

174 Recently, dimer-selective and equipotent RAF inhibitors have been developed; however,

175 R1 and CXCR2 bind IL-8 to produce a group of equipotent responses, but their ability to generate othe

176 in which the retina is derived from a set of equipotent retinal progenitor cells (RPCs) that are subj

177 of the acinar cell compartment as a pool of equipotent secretory cells.

178 . 100-fold SK1-selective inhibition, through equipotent SK1/SK2 inhibition, to reversed 100-fold SK2

179 Wnt activity is associated with maintaining equipotent stem cells (SC), Paneth cells and common gobl

180 in activating the IGF-1 receptor, they were equipotent stimulators of ERK1/2.

181 3,5,3'-triiodo-L-thyronine (T3) and T4 were equipotent stimulators of PCNA accumulation in C6, F98,

182 Identifying both the molecule and an equipotent synthetic analogue, its non-canonical TLR2-TL

183 A CF5 cocultured-DC cytokine milieu drove an equipotent Th1 and Th17 response, while M68 promoted gre

184 alpha; therefore, although the factors were equipotent, the maximal effect of LIF > CNTF.

185 contains about a dozen parallel and roughly equipotent through-pathways.

186 s follows from the proliferative activity of equipotent tips that stochastically branch and randomly

187 Compounds 13 and 27, which are practically equipotent to 1, represent minimalistic fragments of the

188 leoyl-2-hydroxyethyl-1-phosphate, was nearly equipotent to 1-oleoyl LPA in both assays.

189 24-oxovitamin D3 is S and this metabolite is equipotent to 1alpha,25(OH)2D3 in suppressing PTH secret

190 The 3-oxatrien-11-yne analogue, 5, is equipotent to 2 in an animal model of inflammation but h

191 idinoacetic acid analogue 7 were found to be equipotent to 2, leading eventually to the discovery of

192 809 because the S809A mutation made 2-BisPEB equipotent to 3- and 4-BisPEB (IC(50), 1-2.5 muM).

193 Administration of high-dose rifampin (human equipotent to 35 mg/kg per day) substantially increased

194 ropyl analog 23 was subsequently found to be equipotent to 5, whereas analogs bearing smaller and bra

195 at ranged in pharmacological properties from equipotent to a loss of melanocortin receptor activity a

196 vivo insulin tolerance tests, the dimer was equipotent to Actrapid insulin and possessed a sustained

197 Analogues 8, 15-17, 22, and 23 were equipotent to acyline (IC(50) = 0.69 nM) and degarelix (

198 e-Arg-Trp-Asn-Ala-Phe-Dpr]-Tyr-NH(2) that is equipotent to alpha-MSH at the mMC1, mMC3, and mMC5 rece

199 Moreover, C2'deOAmB is nearly equipotent to AmB against yeast but, within the limits o

200 IC(50) = 1.52 +/- 0.05 muM), and it was also equipotent to camptothecin as a Top1 inhibitor.

201 igation has provided optimal Top1 inhibitors equipotent to camptothecin that demonstrate low nanomola

202 lative to CCK-8, some of these compounds are equipotent to CCK as anorectic agents in rats following

203 lls and non-transformed IEC6 cells, HBD2 was equipotent to CCL20 in stimulating migration.

204 Several compounds were equipotent to chloroquine as inhibitors of the 3D7 strai

205 It is equipotent to cocaine at inhibiting dopamine uptake in-v

206 the shortest reported analogue of CRF to be equipotent to CRF (70% IA), the corresponding linear ana

207 ys33,Nle38]hCRF(8-41), the shortest sequence equipotent to CRF reported to date.

208 = 1.47 nM) (32) yielded analogues that were equipotent to degarelix (2) in vitro (IC(50) = 1.64 nM)

209 d by the didemnin analogue, tamandarin A, is equipotent to didemnin B.

210 behaviors maintained by food, with 34 and 36 equipotent to each other and both more potent in behavio

211 mptothecin against the type I enzyme but was equipotent to etoposide against topoisomerase IIalpha.

212 we found that 7alpha-fluoro ginkgolide B was equipotent to ginkgolide B underlining the critical impo

213 In vitro, stressin1-A was equipotent to h/rCRF to release ACTH.

214 homopiperidine analogue 11, was found to be equipotent to haloperidol.

215 ts, suggesting that such combinations may be equipotent to higher-dose single agents.

216 ethyl group of adenophostin, was found to be equipotent to Ins(1,4,5)P3, demonstrating the tolerance

217 CSF-1 is equipotent to insulin in its ability to stimulate 2-[3H]

218 Deglycosylated glycodelin was equipotent to intact glycodelin in the monocyte migratio

219 17R-RvD2 activated the RvD2 receptor and was equipotent to its epimer RvD2.17R-RvD2 also significantl

220 A BCP analogue (22) was found to be equipotent to its parent phenyl compound and showed sign

221 m-LHRH was equipotent to l-LHRH-III to release FSH, but also had a

222 nists with antiparkinsonian effects that are equipotent to levodopa is unknown.

223 of LPA, although none of the compounds were equipotent to LPA.

224 irmed this prediction, as (R)-2 proved to be equipotent to LSD in rats trained to discriminate LSD fr

225 of 1 was fully efficacious and approximately equipotent to morphine in the mouse warm water tail with

226 d all-D-amino acid (enantio) C-peptides were equipotent to native C-peptide, which indicates that the

227 [Ala(14)]-MCH was equipotent to native MCH in its ability to bind to and a

228 pounds were more potent than benztropine and equipotent to or slightly less potent than their previou

229 HSP90alpha/beta inhibitors were found to be equipotent to pan-HSP90 inhibitors in promoting the clea

230 ain revealed that a trisaccharide variant is equipotent to QS-21, while the corresponding disaccharid

231 ADP-ribosyltransferase, the frontrunners are equipotent to rifabutin, suggesting superior clinical ut

232 F-PRT was equipotent to S-PRT in control of two murine sarcoma mod

233 One of the engineered compounds is equipotent to salinosporamide A in inhibition of the chy

234 12 +/- 3 microM, where the trans isomer was equipotent to that of the saturated C(10)-DECA.

235 und with an EC50 of 100 picomolar, which was equipotent to the 332-amino acid natural cytokine in cel

236 a multiple myeloma cell line and found to be equipotent to the best current N-BP drugs.

237 AC) inhibitors is finding alternative motifs equipotent to the classic and ubiquitously used hydroxam

238 C-terminal domain of AGRP, AGRP(87-132), is equipotent to the full-length peptide, further truncatio

239 12; these inhibitors were thus approximately equipotent to the known inhibitor 14(IC50 = 0.22 nM) fro

240 tic biotin-avrainvillamide conjugate, nearly equipotent to the natural product in inhibiting the grow

241 PC-1505 was essentially equipotent to the original C34 peptide and to T-20 in vi

242 scomycin, C24-deoxyascomycin was found to be equipotent to the parent compound both in its immunosupp

243 aldehyde bisulfite adducts were found to be equipotent to the precursor aldehydes.

244 atent EGF receptor, Ras-dependent pathway is equipotent to the Ras-independent pathway, but is masked

245 ue was a pure P2Y(1) receptor antagonist and equipotent to the ribose analogue (MRS 2179).

246 and CSM cells, bimatoprost was approximately equipotent to the selective FP receptor agonists flupros

247 Rivastigmine was equipotent to the specific acetylcholinesterase inhibito

248 -40% relative potency), and 4 analogues were equipotent to the standard.

249 d all D-amino acid containing analogues were equipotent to their counterparts in a cell-based assay w

250 The effects of ANP were equipotent to those caused by C-ANP 4-23, a peptide that

251 ibitors, paroxetine and imipramine, in doses equipotent to those of fluoxetine in inhibiting brain se

252 , including Fab59, which was estimated to be equipotent to TPO.

253 Also unexpectedly, TxA(3) is about equipotent to TxA(2) at the TP alpha receptor.

254 5-Iodo-UDP 32 (EC50 = 0.15 microM) was equipotent to UDP, while substitutions of the 2'-hydroxy

255 4-Thio analogue 13 was equipotent to UDPG, but S-alkylation was detrimental.

256 rans)-1-aza-5-phenyl[4.4.0]decane (12a), was equipotent to unconstrained threo-MP against [(3)H]WIN35

257 es, we found O-GlcNAcylated analogs that are equipotent to unmodified peptide in cell-based activatio

258 thanocarba-uridine 5'-triphosphate (UTP) was equipotent to UTP as an agonist at human P2Y2 receptors

259 e identified seven analogues that are either equipotent to, or 3 times more potent than, the assay st

260 neurons differentiate from among a field of equipotent undifferentiated cells is the process of R8 p

261 ol, two new long-acting beta 2-agonists were equipotent (values of negative log molar concentration e

262 n reciprocal signaling between the AC and an equipotent VU cell.

263 LIN-3/EGF induces the equipotent vulval precursor cells (VPCs) in Caenorhabdit

264 Two equipotent water-soluble amide analogues of nocathiacin

265 lpha-isomer 19b (Ki = 211 nM) and was nearly equipotent with (-)-19a and (+)-20a as well as with coca

266 In addition, 3 was equipotent with 1 and 2 in [(3)H]dopamine uptake inhibit

267 The C-2 H E isomer was found to be equipotent with 1, while the C-2 Me Z isomer was inactiv

268 regioisomers 5,6-, 8,9- and 14,15-DHET were equipotent with 11,12-DHET in activating BK channels.

269 n binding and functional cellular assays and equipotent with 17.

270 at concentrations as low as 10(-)12 M and is equipotent with 1alpha, 25(OH)2D3.

271 nist of the rapid, nongenomic responses, was equipotent with 1alpha, 25-(OH)2D3 in inducing PI3 kinas

272 ed potency: 47 is less potent than 1, 83m is equipotent with 2, and 86 is less potent than 2.

273 The (2R,3S)-analogue of 6 was equipotent with 6 while the (2S,3S)- and (2R,3R)-analogu

274 high affinity for the GnRH receptor and were equipotent with acyline in the AOA.

275 Importantly, most betide diastereomers were equipotent with Acyline.

276 he peracetyl glycosides were, in most cases, equipotent with aglycones.

277 T cell activation and expansion was equipotent with CD55 or CD28 costimulation; however, CD5

278 nsion and multifunctional cytokine responses equipotent with conventional injectable routes of immuni

279 5 has greater potency than verapamil and is equipotent with cyclosporin A, for inhibiting P-glycopro

280 monosubstituted analogues, which are roughly equipotent with each other.

281 e with a cyclohexylmethyl P1 substituent was equipotent with its difluoro ketone counterpart, providi

282 Estrone quinol was also equipotent with its parent estrogen in reducing lesion v

283 tion products of LXB4 isolated from PMN were equipotent with LXB4 for monocyte adherence.

284 idamole analogue has been identified that is equipotent with NBMPR.

285 than the MDAN congeners and were essentially equipotent with one another and oxymorphone.

286 N-AB-PT was found equipotent with paclitaxel in promoting microtubule poly

287 PhTX-343 against NMDA, but was approximately equipotent with PhTX-343 against a kainate challenge.

288 by bacterial expression, demonstrated to be equipotent with PKIbeta-70, and also now demonstrated to

289 ely 2.3 nM for A549 human lung cancer cells, equipotent with PTX in vitro.

290 Synthetic rANP(REA18) was equipotent with rANP in stimulating cGMP production from

291 Compound (-)-(1R, 2R)-11 was equipotent with RSR13 in whole blood, is a candidate for

292 ptide including acidic Glu in position 2 was equipotent with secretin at E373R while being much less

293 ed in two analogues that were less potent or equipotent with similar selectivity, respectively.

294 This mitogenic effect was equipotent with that of platelet-derived growth factor w

295 (+)-20a (Ki = 60 nM) were found to be almost equipotent with the high-affinity binding components of

296 corresponding gamma-glutamyl conjugate were equipotent with the parent compounds.

297 These stabilized analogues are nearly equipotent with their parent peptide in cyclic AMP activ

298 al effects of these drugs were approximately equipotent with those of cocaine.

299 A vitronectin-binding mutant of PAI-1 was equipotent with wild-type PAI-1 in inducing collagen acc

300 terized by the S- and R-isomers being nearly equipotent, with IC50 values of 51 and 22 microM in the