ライフサイエンスコーパス: ergosterol

1 HMG-CoA reductase protein and total cellular ergosterol.

2 nding interaction between amphotericin B and ergosterol.

3 cloheximide and resulted in new synthesis of ergosterol.

4 Here, we demonstrate that Sre1-Scp1 senses ergosterol.

5 en these states is cooperatively mediated by ergosterol.

6 ogenesis of phospholipids, sphingolipids, or ergosterol.

7 lated sterols or a decrease in the amount of ergosterol.

8 btain a strain that accumulated biosynthetic ergosterol.

9 ugh classified as a fungus, P. carinii lacks ergosterol.

10 glycerol, phosphatidic acid, and cholesterol/ergosterol.

11 S but not heat could be rescued by exogenous ergosterol.

12 n the biosynthesis of fungal membrane sterol ergosterol.

13 t both scavenges cholesterol and synthesizes ergosterol.

14 ltrasound-assisted extraction conditions for ergosterol.

15 inhibiting the production of fumonisins and ergosterol.

16 aflatoxins (B1, B2, G1 and G2), patulin, and ergosterol.

17 d higher values for protein (18.34 g/100 g), ergosterol (0.60 mg/g), mycelial biomass (183 mg/g) and

18 hosphatidylcholine (DMPC), cholesterol/DMPC, ergosterol/1-palmitoyl-2-oleoyl-L-alpha-phosphatidylchol

19 Soxhlet extraction, yielding 671.5 +/- 0.5mg ergosterol/100 g dw.

20 ntaining the "promoter" sterols cholesterol, ergosterol, 25-hydroxycholesterol, epicholesterol, or di

21 In a mixture [POPC/POPE/POPS/PI/ergosterol (30:20:5:20:25)] which mimicked the lipid com

22 ble yield increases (up to 2 times higher in ergosterol, 46% in phenolic compounds and 25% in antioxi

23 Ergosterol (5,7,22-ergostatrien-3beta-ol) and ergosteryl

24 horus marzuolus presented high quantities of ergosterol (6.4-6.8 mg/g, dry matter) followed by Pleuro

25 A mammalian analog of ergosterol, 7-dehydrocholesterol (7-DHC), accumulates in

26 pt found in the host strain, and synthesized ergosterol, a Delta(5,6) sterol.The Darlington strain wa

27 Surprisingly ergosterol, a fungal sterol, and 7-dehydrocholesterol, a

28 AmB primarily kills yeast by simply binding ergosterol, a lipid that is vital for many aspects of ye

29 Ergosterol, a molecule with high commercial value, is th

30 sterol concentrations), production (based on ergosterol accrual in ingrowth cores), and turnover rate

31 s (cholesterol, cholestanol, brassicasterol, ergosterol), allochthonous (stigmasterol, beta-sitostero

32 ornucopioides, contained significantly lower ergosterol amounts (0.2-0.4 mg/g).

33 e-specific C24-methylated sterols, including ergosterol and 5-dehydroepisterol.

34 2AR, as shown with control experiments using ergosterol and a control membrane protein (KpOmpA).

35 es its occupancy time on many of the induced ergosterol and anaerobic gene promoters, increases its a

36 to two subsamples, one that was analysed for ergosterol and another that was analysed for DON by HPLC

37 DPPC vesicles; approximately 7 vol% more for ergosterol and approximately 10 vol% more for cholestero

38 enrichment in gene families associated with ergosterol and cell wall biosynthesis, cell growth, iron

39 These data support the idea that ergosterol and cholesterol do enhance survivability for

40 nted a RMSEP of 1.17 mg/kg and 501 ug/kg for ergosterol and DON, respectively.

41 rdering and in the distributions of the drug-ergosterol and drug-cholesterol complexes within the mem

42 major sterol of Acanthamoeba castellanii is ergosterol and identify novel putative precursors and in

43 studied by quantification of their marker - ergosterol and important mycotoxins (aflatoxins B1, B2,

44 ane density (K(a) approximately 750 for DPPC/ergosterol and K(a) approximately 1100 mN/m for DPPC/cho

45 . bellinii mycelia showed higher contents of ergosterol and phenolic compounds (also higher in its fr

46 resistance to methotrexate and antimony, for ergosterol and phospholipid metabolism genes in resistan

47 However, ergosterol and Prm1 have independent functions and only

48 ich is a vital enzyme in the biosynthesis of ergosterol and related 24-alkyl sterols.

49 Ergosterol and sphingolipid biosynthetic pathways had bl

50 Isolation of ergosterol and sphingolipid-enriched Chlamydomonas flage

51 ons of REO, the effects on the production of ergosterol and the biomass of mycelium varied, as did th

52 unexpected mitotic peak in the abundance of ergosterol and thiamine biosynthesis enzymes.

53 technique allowed a rapid separation of free ergosterol and two ergosteryl derivatives occurring in m

54 rts the hypothesis that yeast cells increase ergosterol and unsaturated lipid content to prevent inte

55 Surprisingly, C2'deOAmB binds ergosterol and, within the limits of detection of this e

56 over a wide range of sterol (cholesterol and ergosterol) and ethanol concentrations.

57 cillium and Aspergillus spp., beta-D-glucan, ergosterol, and bacterial or fungal quantitative polymer

58 holesterol, lathosterol, dihydrocholesterol, ergosterol, and desmosterol), and six do not (25-hydroxy

59 ed one of the sterol molecules: cholesterol, ergosterol, and lanosterol.

60 We find that phosphatidylserine and ergosterol are essential for Lyp1 function, and the tran

61 hosphatidylethanolamine, diacylglycerol, and ergosterol) are essential.

62 ne cholesterol may have been used to replace ergosterol, as has been reported in vitro.

63 he key pathway metabolites MEV, squalene and ergosterol, as well as the farnesyl pyrophosphate (FPP)-

64 A new ergosterol auxotroph unable to grow on 3-ketosterols wit

65 An ergosterol auxotroph unable to synthesize sterol or grow

66 the nonvesicular transfer of cholesterol and ergosterol between membranes in vitro.

67 EMM C was determined by the analysis of ergosterol (biomass), chitin (total bio- and necromass)

68 orters (pmr1, pdr5, and vacuolar H+-ATPase), ergosterol biosynthesis (erg3, erg6, and erg24), intrace

69 uction of TD in parallel with a reduction of ergosterol biosynthesis and an unexpected increase in th

70 tion of GPI biosynthesis in C. albicans with ergosterol biosynthesis and hyphal morphogenesis.

71 w oxygen, Sre1p activates genes required for ergosterol biosynthesis and iron uptake.

72 catalyzes the first postcyclization step in ergosterol biosynthesis and is inhibited by triazole dru

73 itive regulators, highlighting key roles for ergosterol biosynthesis and N-linked glycosylation.

74 PI19, of GPI-GnT exhibit opposite effects on ergosterol biosynthesis and Ras signaling (which determi

75 GPI-GnT subunits independently interact with ergosterol biosynthesis and Ras signaling.

76 xposure primarily affected genes involved in ergosterol biosynthesis and sterol uptake; caspofungin e

77 Our finding that CoA metabolism controls ergosterol biosynthesis and susceptibility to antifungal

78 agas disease, Trypanosoma cruzi, by blocking ergosterol biosynthesis at the level of inhibition of la

79 500 mug/mL, and 4000 and 5000 mug/mL reduced ergosterol biosynthesis by 57% and 100%, respectively.

80 in 80% or greater inhibition of overall mean ergosterol biosynthesis compared to that in the drug-fre

81 Phylogenetic trees inferred from an ergosterol biosynthesis gene (erg-3) were highly discord

82 ediated by changes both in the expression of ergosterol biosynthesis genes and in the levels of stero

83 cluding a coinduction of anaerobic genes and ergosterol biosynthesis genes, biosynthesis of basic ami

84 eroxide stress with concurrent repression of ergosterol biosynthesis in an SRX1-independent manner.

85 entified gene encoding an enzyme involved in ergosterol biosynthesis in Saccharomyces cerevisiae has

86 As a model system, we studied ergosterol biosynthesis in single living fission yeast c

87 uced expression of genes encoding enzymes of ergosterol biosynthesis in yeast (ERG genes).

88 fungal infections and functions by blocking ergosterol biosynthesis in yeast.

89 the clones were also highly resistant to the ergosterol biosynthesis inhibitor posaconazole, a drug p

90 protects actively dividing amastigotes from ergosterol biosynthesis inhibitors (azoles), independent

91 growth in the presence of low levels of the ergosterol biosynthesis inhibitors, itraconazole and 25-

92 the presence of nonlethal concentrations of ergosterol biosynthesis inhibitors, Ustilago maydis alte

93 alters the susceptibility of yeast cells to ergosterol biosynthesis inhibitors.

94 e typically treated with azole inhibitors of ergosterol biosynthesis often leading to drug resistance

95 by reversing the antifungal's effect on the ergosterol biosynthesis pathway.

96 In contrast, perturbation of ergosterol biosynthesis reduces PC and GlcCer transport

97 these subunits indicates that GPI19 controls ergosterol biosynthesis through ERG11 levels, whereas GP

98 Inhibition of ergosterol biosynthesis was detected at a concentration

99 acid metabolism, adherence, drug resistance, ergosterol biosynthesis, and beta-glucan synthesis.

100 1 are required for both normoxic and hypoxic ergosterol biosynthesis, and therefore cells lacking SRE

101 expression in response to a block in de novo ergosterol biosynthesis, brought about by antifungal dru

102 n of ERG2, ERG6 and ERG9, genes required for ergosterol biosynthesis, during both aerobic and hypoxic

103 ly, high copies of a single gene involved in ergosterol biosynthesis, ERG25, rescued this growth defe

104 a broad-spectrum antifungal agent inhibiting ergosterol biosynthesis, exhibits synergy with the beta-

105 ions in any of ERG genes 3-6, lacking normal ergosterol biosynthesis, have fragmented vacuoles.

106 Saccharomyces cerevisiae ergosterol biosynthesis, like cholesterol biosynthesis i

107 tifungal drugs, due to its ability to modify ergosterol biosynthesis, mitochondrial function, or anti

108 conazole, an antimicrobial drug that targets ergosterol biosynthesis, only affected the lipogenesis i

109 These include ergosterol biosynthesis, phosphatidylinositol (4,5)-bisp

110 g the enzyme that catalyzes the last step of ergosterol biosynthesis, that impair both shmoo formatio

111 ylase (CYP51) genes, which are essential for ergosterol biosynthesis, to restrict fungal infection.

112 desaturase gene (ERG3), essential for yeast ergosterol biosynthesis, was cloned and sequenced from C

113 , and because fluconazole acts by inhibiting ergosterol biosynthesis, we developed a novel method to

114 nes revealed a specific biochemical pathway--ergosterol biosynthesis--where the expression of multipl

115 f sterol intermediates and the activities of ergosterol biosynthesis-targeting antifungals.

116 arbon 24 in the final step of cholesterol or ergosterol biosynthesis.

117 enzyme, Erg11p, a key regulatory protein in ergosterol biosynthesis.

118 enes, including three ERG genes required for ergosterol biosynthesis.

119 ads to defects in several enzymatic steps in ergosterol biosynthesis.

120 ignated ERG28, was strongly coregulated with ergosterol biosynthesis.

121 also of genes associated with virulence and ergosterol biosynthesis.

122 2p and Ecm22p, bind to the promoters of most ergosterol biosynthetic (ERG) genes, including ERG2 and

123 two phospholipid methyltransferases, several ergosterol biosynthetic enzymes, and a group of bacteria

124 st that proper transcriptional regulation of ergosterol biosynthetic genes by Mot3 is important for n

125 sistance, particularly to the azole class of ergosterol biosynthetic inhibitors, is a growing global

126 s can be mediated by increased expression of ergosterol biosynthetic intermediates.

127 All but two genes involved in the ergosterol biosynthetic pathway in Saccharomyces cerevis

128 disruption, but instead by disruption of the ergosterol biosynthetic pathway via inhibition of the 14

129 important for the expression of genes in the ergosterol biosynthetic pathway, including the rate-limi

130 onstrated a heme-related function within the ergosterol biosynthetic pathway.

131 tion, and ERG6 is a methyltransferase in the ergosterol biosynthetic pathway.

132 am of the sites of TBF and ITZ action in the ergosterol biosynthetic pathway.

133 Here we demonstrate a link between TAFC and ergosterol biosynthetic pathways, which are both critica

134 complex that is tethered to the membrane by Ergosterol biosynthetic protein28 (ERG28).

135 ns in yeast and analyzed compounds that bind ergosterol biosynthetic proteins and protein kinases.

136 lase as treatment inhibits the production of ergosterol, but results in the accumulation of the lanos

137 1) at 1.5-1.9 A resolution in complexes with ergosterol, cholesterol, and 7-, 20- and 25-hydroxychole

138 drogenase-like)), an essential enzyme in the ergosterol/cholesterol biosynthesis pathway.

139 ls a clear quantitative relationship between ergosterol concentration in the endoplasmic reticulum an

140 ncile an equilibration process with the high ergosterol concentration of the PM relative to ER, we no

141 s study, EFM standing biomass (based on soil ergosterol concentrations), production (based on ergoste

142 or mevalonate, iron starvation decreased the ergosterol content and composition, a phenotype that is

143 Furthermore, ergosterol content increases during filamentous growth.

144 ceptible isolates showed a mean reduction in ergosterol content of 72% after exposure to 1 microg of

145 resistant isolates showed mean reductions in ergosterol content of only 25, 38, 53, and 84% after exp

146 branes in spf1 cells become similar in their ergosterol content to mitochondrial membranes.

147 The ergosterol content varied considerably depending on the

148 No significant differences in mean ergosterol content were observed between any of the isol

149 ion of Ne-TML was related to the decrease in ergosterol content, membrane ions leakage, impairment in

150 n distribution in yeast strains with reduced ergosterol content, they phenocopied the loss of Spf1.

151 ntration of AmB also had the lowest membrane ergosterol content.

152 ignificantly correlated with the patulin and ergosterol contents in mouldy and hidden mould hazelnuts

153 significant correlation between patulin and ergosterol contents of mouldy and hidden mould hazelnuts

154 e that, upon introduction of cholesterol and ergosterol, contrary to previous belief the mechanical s

155 It is proposed that ergosterol-dependent inhibition of membrane proteins is

156 If a mating pair forms between ergosterol-depleted cells despite the attenuated pheromo

157 esults have led to a model in which heme and ergosterol depletion alters membrane fluidity, thereby a

158 Ergosterol depletion independently inhibits two aspects

159 A series of stigmasterol and ergosterol derivatives, characterized by the presence of

160 In this study, the ergosterol-derived photoproducts previtamin D(2), lumist

161 We now find that the "regulatory lipids" ergosterol, diacylglycerol and 3- and 4-phosphoinositide

162 homotypic fusion requires regulatory lipids (ergosterol, diacylglycerol, and phosphoinositides), the

163 oefficient for partitioning of nystatin into ergosterol/dimyristoyl-L-alpha-phosphatidylcholine (DMPC

164 he lifetime of a phospholipid molecule in an ergosterol-dipalmitoylphosphatidylcholine complex is est

165 In ergosterol/DMPC bilayers, for example, there is a >3-fol

166 .2, 0.222, and 0.25 sterol mole fractions in ergosterol/DMPC mixtures.

167 ng in the purification and identification of ergosterol endoperoxide, a B-ring oxysterol.

168 orded the compounds alpha-linolenic acid and ergosterol endoperoxide, which were active against Crypt

169 CS-PAEO-Nm treatment significantly inhibited ergosterol, enhanced leakage of ions and induced impairm

170 Ergosterol (ERG) had a weak antagonistic effect.

171 ), phosphatidic acid (PA), cardiolipin (CL), ergosterol (ERG), diacylglycerol (DAG), and phosphatidyl

172 channels in membranes containing the sterol, ergosterol (erg).

173 (1.4-fold), free fatty acids (1.7-fold), and ergosterol ester (1.8-fold), and a decrease in diacylgly

174 lower eukaryotes including fungi (containing ergosterol) exhibit an intermediate degree of sensitivit

175 The by-product generated after ergosterol extraction from mushrooms (A. bisporus) is ri

176 of the ethanol concentration was high in the ergosterol extraction yield (2 times higher yields in 96

177 It required ergosterol for growth and produced E,E-farnesol.

178 The need for ergosterol for vacuole priming underscores the role of l

179 vents were evaluated for green extraction of ergosterol from mushroom.

180 ways in transporting the major yeast sterol, ergosterol, from its site of synthesis to the PM.

181 ls on fusion rates, we utilized the nystatin/ergosterol fusion assay to measure fusion of liposomes t

182 and a maximum extraction yield of 6995.00 ug ergosterol/g dry weight mushroom was attained with menth

183 ith n-hexane extracts with higher purity (mg ergosterol/g extract) were obtained.

184 robic AR1b elements act in trans to regulate ergosterol gene expression.

185 unique within the Fungi, such as the lack of ergosterol, genetic complexity of surface antigens, and

186 osure, that is, sum of indicators for fungi (ergosterol), Gram-positive (muramic acid) bacteria, and

187 Ergosterol has been shown to be required for endocytosis

188 Oxygen-requiring biosynthetic pathways for ergosterol, heme, sphingolipid, and ubiquinone were prim

189 In addition, also cholesterol and ergosterol, if present, are evaluated in all the samples

190 ette aspiration suggest that cholesterol and ergosterol impact the order and microstructure of the ge

191 t approximately 40 mol% both cholesterol and ergosterol impart similar condensation to the membrane (

192 efects and the accumulation of intracellular ergosterol in drs2 mutants.

193 such as cholesterol in higher eukaryotes or ergosterol in fungi may regulate the VDAC oligomeric sta

194 pecific enzymatic steps in the production of ergosterol in fungi or phytosterols in plants.

195 ey enzyme intermediating the biosynthesis of ergosterol in fungi, and the target of azole fungicides.

196 e generation of non-vitamin D(2) products of ergosterol in mushrooms has not been reported.

197 The production of vitamin D(2) from ergosterol in mushrooms upon exposure to ultraviolet (UV

198 contained sphingomyelin in place of DPPC, or ergosterol in place of cholesterol, it appeared that thi

199 ycerides, diglycerides, free fatty acids and ergosterol in salmon oil.

200 pid (DPPC), an unsaturated lipid (DOPC), and ergosterol in the presence of high ethanol (20 vol %).

201 ectroscopy to assess the presence of DON and ergosterol in wheat samples through prediction and class

202 lls and also for inhibition of biosynthesis: ergosterol in yeasts and cholesterol in human cells.

203 ylcholine (DPPC) and sterols (cholesterol or ergosterol) in water and water/ethanol solutions have be

204 The stability of ergosterol, in terms of the formation of ergosterol pero

205 Furthermore, the presence of cholesterol and ergosterol increases acyl chain order in the liquid crys

206 Binding ergosterol, independent of channel formation, is the pri

207 ,11-seco-motif was obtained by conversion of ergosterol into a 9,11-secoenol ether employing a mercur

208 In fungi, ergosterol is an essential component of the plasma membr

209 We find that although sphingolipid-free ergosterol is concentrated at sites of cell-cell contact

210 Ergosterol is depleted from this periprotein lipidome, w

211 e to ER, we note that a large fraction of PM ergosterol is found condensed with sphingolipids in memb

212 is optimally required during aerobiosis when ergosterol is plentiful.

213 nding interaction between amphotericin B and ergosterol is required for both forming ion channels and

214 a two-atom change in the aliphatic moiety of ergosterol is sufficient to obstruct cell shape remodeli

215 Ergosterol is thought to form microdomains within the me

216 heme is still required for the synthesis of ergosterol, its precursor, lanosterol, is instead incorp

217 ), 25-epiminolanosterol (Ki value of 49 nm), ergosterol (Ki value of 27 microm) and 26,27-dehydrozymo

218 of sterol production, a marked change in the ergosterol/lanosterol ratio, accumulation of sterols in

219 ome resistant to BFA, indicating that proper ergosterol levels are needed for antifungal drug resista

220 Higher ergosterol levels in combination with the proteins Fhn1,

221 f Hhp2 increases Sre1N protein stability and ergosterol levels in the presence of oxygen.

222 Sterol analyses showed that ergosterol levels were significantly decreased (P < 0.00

223 The ergosterol ligands filipin, nystatin and amphotericin B

224 lization synergizes with the activity of the ergosterol molecule-targeting antifungal amphotericin B

225 fic interaction with the main fungal sterol, ergosterol, often resulting in membrane permeabilization

226 hosphatidylinositol-3-phosphate [PI(3)P] and ergosterol on TBSV replication.

227 arly spaced densities that may correspond to ergosterol or bound detergent, around the c-ring.

228 Ergosterol or cholesterol delivery to wild-type vacuoles

229 d clinically for deep mycosis act by binding ergosterol or disrupting its biosynthesis.

230 ith model membranes containing stigmasterol, ergosterol, or lanosterol.

231 free energy profiles for the dimerization in ergosterol- or cholesterol-containing and sterol-free me

232 ) and the radiation time (10 min), the lower ergosterol oxidation was observed.

233 Supplementation with ergosterol partially suppressed the shmooing defect but

234 In signaling, ergosterol participates in the recruitment of Ste5 to a

235 ncreases and decreases in the level of these ergosterol pathway intermediates induce Sre1 proteolysis

236 ich bears genes expressing the enzyme in the ergosterol pathway targeted by azole drugs, efflux pumps

237 l amphotericin B and antagonizes that of the ergosterol pathway-targeting antifungal drug terbinafine

238 e also demonstrate that the oxidized sterol, ergosterol peroxide, is necessary and sufficient for Vms

239 of ergosterol, in terms of the formation of ergosterol peroxide, was evaluated under different stora

240 The extraction kinetics at 25 degrees C of ergosterol, phenolic compounds and antioxidant activity

241 t vacuole fusion requires regulatory lipids (ergosterol, phosphoinositides, and diacylglycerol), the

242 t(1/2) approximately 10-15 min) of ER and PM ergosterol pools via a bidirectional, nonvesicular proce

243 eoyl-L-alpha-phosphatidylcholine (POPC), and ergosterol/POPC/1-palmitoyl-2-oleoyl-L-alpha-phosphatidy

244 study, we show that the accumulation of only ergosterol precursors with a conjugated double bond in t

245 Accumulation of only ergosterol precursors with a conjugated double bond in t

246 er is upregulated in strains that accumulate ergosterol precursors.

247 te (7-DHC and desmosterol) and evolutionary (ergosterol) precursors of cholesterol on membrane dipole

248 her found that not only cholesterol but also ergosterol present in protozoa was palmitoylated by PlaC

249 uconazole-resistant isolates by quantitating ergosterol production in cells grown in 0, 1, 4, 16, or

250 The effects of GEO on fumonisin and ergosterol production were evaluated at concentrations o

251 ,7 sterol isomerase activity (i.e. wild-type ergosterol production) by enhanced resistance to the ant

252 Like mutants that affect ergosterol production, the viable combinations of OSH de

253 Thus, the sphingolipid-free pool of ergosterol promotes plasma membrane fusion.

254 ows that increasing unsaturated lipid and/or ergosterol protects the membrane by preventing the forma

255 cyclolaudenol, 24(28)-methylenecycloartanol, ergosterol, protothecasterol, 4alpha-methylergostanol, 4

256 that HSI-NIR may be a suitable technique for ergosterol quantification and DON classification of samp

257 Leishmania synthesize ergosterol rather than cholesterol, making this pathway

258 Ten SDD isolates showed mean ergosterol reductions of 38, 57, 73, and 99% after expos

259 hat perturbs synthesis of the membrane lipid ergosterol results in potent, synergistic fungicidal act

260 The opposite results were observed with ergosterol-rich procyclic cells.

261 edure by applying it to identify a model for ergosterol sensing by the proteins Sre1 and Scp1 in fiss

262 Interestingly, when grown in the presence of ergosterol set1Delta cells become resistant to BFA, indi

263 e or zero amounts of aflatoxins, patulin and ergosterol, so they posed no risk for the consumer when

264 endocytosis) and endogenous (biosynthesis of ergosterol) sources.

265 Treatment with ergosterol-specific amphotericin B does not.

266 This is attributable to ergosterol-specific and reversible inhibition of membran

267 ing protein homologue Kes1/Osh4 and regulate ergosterol subcellular distribution.

268 gly, when erg27 was grown on cholesterol- or ergosterol-supplemented media, the endogenous compounds

269 y both CoCl2 and low oxygen were involved in ergosterol synthesis and in iron/copper transport.

270 to stabilize Erg11p, which in turn regulates ergosterol synthesis and MMS resistance.

271 terol, a sterol found in the cholesterol and ergosterol synthesis pathways, do not exhibit coexisting

272 ein Erg11/Cyp51 catalyzes a critical step in ergosterol synthesis, and the azole class of antifungal

273 Further, alpha-TCsNe inhibited ergosterol synthesis, methylglyoxal (the aflatoxin enhan

274 and virulence, including those in late stage ergosterol synthesis, or early steps in fatty acid or ri

275 ed genes were in the pathways of protein and ergosterol synthesis.

276 responsible for the final reduction step in ergosterol synthesis.

277 es apoptosis-like changes and alterations in ergosterol synthesis.

278 from B311 but not from Dar-1 showed restored ergosterol synthesis.

279 constructed a phase diagram of the DPPC/DOPC/ergosterol system at 20 vol % ethanol.

280 Screening for resistance to the ergosterol-targeting fungicide amphotericin B (AmB) reve

281 ificantly less favorable in the bilayer with ergosterol than in the cholesterol-containing or sterol-

282 ol for all YLR228c and UPC2 combinations was ergosterol, the consensus yeast sterol.

283 s the role of the ARE2 enzyme is to esterify ergosterol, the end product of the pathway.

284 enes encoding biosynthetic enzymes that make ergosterol, the major fungal membrane sterol, are regula

285 cells allows sterols such as cholesterol and ergosterol to be actively taken up under aerobic conditi

286 iculum (ER) and redistribution of endogenous ergosterol to intracellular membranes, phenotypes that a

287 contact sites depends on a balanced ratio of ergosterol to sphingolipids.

288 to show that transport of newly synthesized ergosterol to the PM is unaltered in cells defective in

289 ion of DAN1 and PDR11, two genes involved in ergosterol uptake.

290 Ergosterol was 95% degraded after 150 days in powders wi

291 The ergosterol was exposed to ultra-violet radiation for con

292 Ergosterol was found to bind many proteins and may funct

293 Ergosterol was identified by its unique spectrophotometr

294 Ergosterol was investigated as antioxidant.

295 Ergosterol was isolated from whole yeast cells by saponi

296 The extracted ergosterol was purified using a novel methodology and th

297 All aflatoxins, patulin and ergosterol were determined by high performance liquid ch

298 ssociated with higher contents in sugars and ergosterol, while the 5 kGy dose, independently of irrad

299 nd relative abundances of all isotopomers of ergosterol whose carbon atoms in the 5,7-diene moiety of

300 38F for ferric heme lowers the production of ergosterol with respect to wild-type Dap1p in S. pombe,