ライフサイエンスコーパス: error-free

1 oderate exercise in humans is isocapnic, or 'error-free'.

2 ly 18% for short reads of 100 bases that are error free).

3 esponding Cq if and only if E is taken to be error free.

4 thesis (TLS) across these N(2)-dG adducts is error free.

5 with recombinational repair must be largely error-free.

6 TLS parameters; almost all residual TLS were error-free.

7 e remaining mitotic divisions appeared to be error-free.

8 ction of lesion bypass and that it is mostly error-free.

9 by homologous recombination, which is mostly error-free.

10 G3 C8-IQ adducts, incorporation was largely error-free.

11 This pathway is error-free.

12 Replication in E. coli was essentially error-free.

13 the approach and extension steps are largely error-free.

14 itude in their preferences for mutagenic vs. error-free 8-oxoG lesion bypass.

15 g along large-angle bending channels for bit-error-free acoustic data transmission in an underwater e

16 ly related oxidized lesions: 8OG allows both error-free and error-prone bypass, whereas Gh or Sp caus

17 s opposite a variety of lesions in both near error-free and error-prone bypass.

18 locus AID-initiated lesions are processed by error-free and error-prone repair.

19 probe the cellular mechanism underlying the error-free and error-prone translesion DNA syntheses, in

20 njugating and DNA-binding activities, in the error-free and mutagenic modes of damage bypass.

21 d by transcriptional bypass, generating both error-free and mutant transcripts with AMP misincorporat

22 on across the two N (2)-alkyl-dG lesions was error-free, and Pol nu and Pol theta were dispensable fo

23 refore highly robust, and produces virtually error-free arrays.

24 n a 24.48-fold increase in the percentage of error-free assembled fragments (from 3.23% to 79.07%).

25 ty ranging from 131-250 targets, we observed error-free assemblies for 90.5% of all targets.

26 act, most of the times, Slicembler generates error-free assemblies.

27 dicts the narrow temperature window in which error-free assembly can occur.

28 units to ensure free energy minimization and error-free assembly.

29 sonic waves to allow for the effective and "error free" assembly wherein an entangled net of fibers

30 With the G1 N 2-IQ adduct, the product was error-free at the site opposite the base and then stalle

31 sylase (UNG), an enzyme normally involved in error-free base excision repair.

32 cess, but the resulting uracils are repaired error-free because error-prone repair does not gain acce

33 spindles suggests that Pkl1p contributes to error-free biorientation by promoting normal spindle pol

34 CTG expansions in conjunction with the error-free branch of postreplication repair (PRR).

35 Owing to the genetic flexibility and error-free bulk production, bio-nanostructures such as f

36 the anti-conformation in human pol gamma for error free bypass of 8-oxo-dG and substitution to Cys al

37 size can be a major factor for efficient and error-free bypass at these adducts by TLS DNA polymerase

38 , PolDIP2 stimulates both the efficiency and error-free bypass of 8-oxo-7,8-dihydrodeoxyguanosine (8-

39 processivity and catalytic efficiency of the error-free bypass of a 8-oxo-G lesion by both Pols eta a

40 is a polymerase enzyme, specialized for near error-free bypass of certain bulky chemical lesions to D

41 Our results highlight a novel mechanism for error-free bypass of deoxyuridines generated within ssDN

42 Replication repair mediates error-free bypass of DNA damage in a series of steps tha

43 This promotes error-free bypass of DNA damage lesions.

44 wo downstream E3 ligases needed to carry out error-free bypass of DNA lesions.

45 nthesis DNA polymerase additionally promotes error-free bypass of GO lesions.

46 merases kappa and iota are necessary for the error-free bypass of N(2)-CEdG and N(2)-CMdG.

47 reover, during RNA extension Poleta performs error-free bypass of the 8-oxoguanine and thymine dimer

48 unts for the dA adduct blockage and the near-error-free bypass of the dG lesion.

49 the other daughter strand, and the result is error-free bypass of the lesion.

50 te, but one that yields mutations instead of error-free bypass.

51 a Lys-63-linked polyubiquitin chain promotes error-free bypass.

52 whereas pol eta is involved primarily in its error-free bypass.

53 rporate a C provides a unique means for the "error-free" bypass of this noninstructional lesion.

54 te, indicating ATXN3's role in PNKP-mediated error-free C-NHEJ.

55 Physicians provided error-free care in 73% of the uncomplicated encounters,

56 Error-free cell division depends on the assembly of the

57 inate the spatiotemporal dynamics needed for error-free cell division.

58 Continuous and error-free chromosome inheritance through the cell cycle

59 the Aurora B kinase) is essential to achieve error-free chromosome segregation during cell division.

60 Error-free chromosome segregation requires stable attach

61 lly demonstrate the possibility of achieving error-free clocked non-volatile spin wave logic device,

62 We conclude that the error-free component of the RAD6/RAD18 pathway completes

63 ately 60-70% of these events depended on the error-free component of the RAD6/RAD18 pathway, with the

64 Error-free, conservative HR involves strand invasion and

65 were assembled in one reaction, we observed error-free constructs for 70.6%.

66 and molecular topologies (treated herein as error-free) contain contradictory groupings across analy

67 s event determines whether an error-prone or error-free damage avoidance pathway is taken.

68 s to putative tumor suppressors and controls error-free damage bypass by an unknown mechanism.

69 polyubiquitin chains, previously involved in error-free damage tolerance.

70 the VAF factorization problem in the case of error-free data and extend this solution to real data wi

71 he method is useful for obtaining systematic error-free data from (13)C tracer experiments and can al

72 d writing but do not offer random-access and error-free data recovery from low-cost, portable devices

73 (instead of easier, as one would expect with error-free data), and as a consequence the quality of th

74 s not appear to regulate other DDT pathways, error-free DDT mechanisms are employed by H2Bub1-deficie

75 steady state levels of APE1 and consequently error free DNA repair.

76 nation (HR) by the RAD51 recombinase enables error-free DNA break repair.

77 Error-free DNA can subsequently be isolated using one of

78 Evidence for an error-free DNA damage tolerance process in eukaryotes (a

79 CNA, pinpointing ZRANB3 as a key effector of error-free DNA damage tolerance.

80 mologous recombination (HR) is important for error-free DNA double strand break repair and maintenanc

81 nabling homologous recombination (HR)-based, error-free DNA double-strand break repair (DSBR) and int

82 r focus formation and its ability to promote error-free DNA interstrand cross-link repair, leading to

83 PH1 functions to channel DNA lesions into an error-free DNA repair pathway.

84 Error-free DNA synthesis involves 8-oxoG adopting an ant

85 Given the impact of error-free DNA synthesis on the genomic integrity and di

86 ICLs in a reaction that involves extensive, error-free DNA synthesis.

87 nscription, repair of transcribed genes, and error-free double-strand break repair of a 3'-phosphate-

88 hia coli and constitute the major pathway of error-free DSB repair.

89 nt mechanistic insights into C-NHEJ-mediated error-free DSBR of the transcribed genome.

90 storing the missing sequences, thus allowing error-free DSBR.

91 nation represents an important means for the error-free elimination of DNA double-strand breaks and o

92 At low DNA/protein ratios, an error-free end-joining mechanism predominated over MHEJ.

93 Efficient, error-free, end joining observed in such in vitro reacti

94 ells, TLS during replication can be markedly error-free even opposite a highly distorting DNA lesion.

95 er Peri:O(6)-BnG base pair, and in contrast, error-free extension was observed for the smaller BIM:O(

96 the TLS machinery to function in a much more error-free fashion than could have been predicted from t

97 a is capable of bypassing 8-oxoG in a mostly error-free fashion, thus preventing GC-->AT transversion

98 bypass and that it occurs in a predominantly error-free fashion.

99 his lesion in human cells occurs in a highly error-free fashion.

100 have similar accuracies predicting genes on error-free fragments, in the presence of sequencing erro

101 t the expense of a reduction in the level of error-free gene conversion.

102 the main determinant of stable heredity and error-free gene expression.

103 rvation of protein function and to guarantee error-free genome annotations, in general: sets with mil

104 Error-free genome duplication and segregation are ensure

105 sting of Shu1, Shu2, Csm2 and Psy3, promotes error-free homologous recombination (HR) by an unknown m

106 uble-strand breaks (DSBs) can be repaired by error-free homologous recombination (HR) or mutagenic no

107 iminished proficiency for DNA repair via the error-free homologous recombination (HR) repair pathway.

108 ngle-stranded DNA facilitates DSB repair via error-free homologous recombination (HR) while stymieing

109 To repair DSBs, error-free homologous recombination (HR), and/or error-p

110 r prone non-homologous end-joining (NHEJ) or error-free homologous recombination.

111 B repair from error-prone DNA end-joining to error-free homologous recombination.

112 BRCA1 promotes error-free, homologous recombination-mediated repair (HR

113 s depletion of EXO1 diverts repair away from error-free homology-dependent repair.

114 ded DNA gap that is repaired primarily in an error-free, homology-directed manner.

115 ction by 53BP1, triggers competition between error-free HR and mutagenic nonhomologous EJ.

116 rate at which information can be transmitted error-free in fibre-optic communication systems?

117 ed translesion synthesis past this adduct is error-free in the context of semiconservative replicatio

118 site, disrupting interactions necessary for error-free incorporation of dC opposite the lesion.

119 sis confirmed that hpol eta catalyzes mainly error-free incorporation of dC, with misincorporation of

120 MD simulations show that the near error-free incorporation of dCTP opposite the major benz

121 HEDGES will find applications in large-scale error-free information encoding.

122 A induce errors within the molecules, making error-free information storage challenging.

123 ly been interpreted as the ultimate limit of error-free information transmission rate.

124 Together, these results suggest that the error-free insertion of dAMP opposite the 3'-T of the ci

125 While we found on-target error-free integration in all examined samples, some mic

126 " the repair process in favor of potentially error-free interchromatid homologous recombination at th

127 t circularizing a barcode sequence can yield error-free k-mers even when the size of k is large relat

128 s to the Rad18-SHPRH complexes necessary for error-free lesion bypass in cells.

129 quitin binding site of Mms2 is necessary for error-free lesion bypass in the RAD6 pathway and provide

130 are required for chain assembly in vitro and error-free lesion bypass in vivo.

131 been postulated to be an intermediate in an error-free lesion bypass pathway.

132 However, strains without error-free lesion bypass proteins Ubc13, Mms2 and Mph1 d

133 irst direct evidence for the existence of an error-free lesion replication mechanism and also demonst

134 egulation of CD4 expression is essential for error-free lineage choice during major histocompatibilit

135 cific positive selection and is critical for error-free lineage choice in TCR-transgenic mice whose t

136 and such rNMPs are efficiently removed in an error-free manner by ribonuclease (RNase) H2.

137 acil lesions are probably counteracted in an error-free manner by the uracil base excision repair pat

138 model ICLs were repaired mostly (>94%) in an error-free manner in both hosts.

139 osite this lesion replicates DNA in a highly error-free manner in human cells.

140 is past C or (m)C in a CPD also occurs in an error-free manner is for an (m)C in the 5'-position of a

141 the a priori expectation that HRR acts in an error-free manner to repress three classes of genetic al

142 lesions at C:G bp was indeed repaired in an error-free manner via Brca2 instead of being processed b

143 ta synthesize past the 3'-(m)C CPD in a >99% error-free manner, consistent with the highly water-expo

144 ay of DNA lesions and act in a predominantly error-free manner, implicates a crucial role for Rev1 in

145 or U in a CPD by pol eta occurs in a highly error-free manner, the only in vitro evidence that synth

146 pposite the phenanthriplatin-dG adduct in an error-free manner, with specificity for CTP incorporatio

147 cellular bypass of the lesion occurred in an error-free manner.

148 ndently of these Pols and in a predominantly error-free manner.

149 lf from the DNA following ETO washout, in an error-free manner.

150 thway repairs DNA double-strand breaks in an error-free manner.

151 tes to lesion bypass in a mutagenic or in an error-free manner.

152 duced photoproducts from DNA in a relatively error-free manner.

153 y is essential for the removal of ICLs in an error-free manner.

154 ymine dimers efficiently and in a relatively error-free manner.

155 Homologous recombination is an error-free mechanism for the repair of DNA double-strand

156 pass of epsilonA proceeded principally by an error-free mechanism in which the undamaged strand was u

157 be repaired by homologous recombination, an error-free mechanism, or by non-homologous end joining,

158 ated by both an error-prone mechanism and an error-free mechanism.

159 eplication can be bypassed by error-prone or error-free mechanisms.

160 protein 1 (53BP1), which results in fast and error-free microhomology-mediated repair and a low mutan

161 microtubule-organizing centers required for error-free mitosis and embryonic development.

162 ection is achieved in prometaphase to ensure error-free mitosis remains unknown.

163 dRrp6 is required for cell proliferation and error-free mitosis, but the core exosome subunit Rrp40 i

164 of microtubule dynamics is essential for an error-free mitosis.

165 appears to be exerted by the RAD5-dependent error-free mode of bypass DNA repair.

166 itination of PCNA by yRad5 (E3) promotes the error-free mode of bypass.

167 report suggested that MacDinB-1 works in an error-free mode to repair cyclobutane pyrimidine dimers.

168 have revealed the previously underestimated error-free nature of NHEJ and provided new tools to furt

169 CC4 complex at DNA breaks, thereby promoting error-free NHEJ.

170 s have shown that poliota is also capable of error-free nucleotide incorporation opposite the bulky m

171 ltage (0.5 VPP) and efficient 0.9 fJ per bit error-free operation.

172 er chromatid recombination (SCR), generating error-free or error-prone homologous recombination (HR)

173 tions of TAM are not affected by the loss of error-free or error-prone lesion bypass pathways, they a

174 Cells employ error-free or error-prone postreplication repair (PRR) p

175 cesses to tolerate genomic lesions by either error-free or error-prone repair.

176 iting higher susceptibility to UNG-triggered error-free or error-prone resolution.

177 tides opposite DNA damage sites resulting in error-free or mutagenic damage bypass.

178 ssed by DNA topoisomerase 1 (Top1) by either error-free or mutagenic repair.

179 NHEJ may either be error-free or mutagenic with deletions or insertions at

180 Homologous recombination (HR), the error-free pathway for double-strand break (DSB) repair,

181 romatid recombination (SCR) is a potentially error-free pathway for the repair of DNA lesions associa

182 antly via translesion synthesis, whereas the error-free pathway functions as a backup system.

183 and context; cells preferentially employ the error-free pathway in S phase and do not require MEC1-de

184 n of double strand DNA breaks proceeds in an error-free pathway of homologous recombination (HR), whi

185 A third error-free pathway relies on the presence of Mms2, but m

186 nt mutagenesis by inhibiting an alternative, error-free pathway that depends on homologous recombinat

187 rases, polyubiquitylation is required for an error-free pathway that probably involves a template swi

188 n synthesis, polyubiquitination activates an error-free pathway, elusive in mammals, enabling damage

189 ars to mediate AFB1-induced mutagenesis when error-free pathways are compromised.

190 directly replicate over the lesion, whereas error-free pathways use an undamaged duplex as a templat

191 ficiency, all groups also had to demonstrate error-free performance.

192 This challenges the popular notion that error-free phonological retrieval requires guidance from

193 d ligand shell for kinetically competent and error-free photo-assembly of the Mn4CaO5-cluster.

194 usually necessary but not sufficient for an error-free plan of care.

195 mechanisms are homologous recombination and error-free postreplication repair (EF-PRR).

196 First, we show that genes in the error-free postreplication repair (PRR) pathway prevent

197 e channeled into recombination-dependent and error-free postreplication repair.

198 proteins dictates the repair of DSBs by the error-free process of homologous recombination (HR).

199 us recombination (HR) pathway, a potentially error-free process that utilizes a homologous sequence a

200 ovides explicit expressions for (1) yield of error-free protein, (2) fraction of prematurely terminat

201 not assume a linear relationship between the error-free read and shadow counts and provides more accu

202 In contrast, fast and efficient error-free reading places more consistent demands on bot

203 e nanopore sequencers, while still producing error-free readouts with the highest reported informatio

204 embly can be performed by k-mer extension in error-free reads, this algorithm is unsuccessful with th

205 ers, especially when comparing the number of error-free reads.

206 se zeta/Rev1 and DNA polymerase eta, and the error-free, recombination-dependent component of this pa

207 -links can be repaired by three pathways: an error-free recombinational pathway requiring NER and HR

208 ted performance indicates the possibility of error-free recovery of petabyte- and exabyte-scale data

209 alse alleles depend upon the availability of error-free reference genotypes or reliable pedigree data

210 hemical evidence to show that BRCA1 promotes error-free rejoining of DSBs in human breast carcinoma c

211 Although error-free repair by homologous recombination (HR) is cr

212 e-dependent inhibitor of cNHEJ that promotes error-free repair by homologous recombination during cel

213 mutant cells to PARP inhibition and restores error-free repair by HR.

214 llegitimate second-end capture to ensure the error-free repair of a DNA double-strand break.

215 that preserves genome integrity by promoting error-free repair of abasic sites in single-stranded DNA

216 or enhance c-myc genomic instability, due to error-free repair of AID-initiated lesions, in Ag-stimul

217 it also serves as the primary mechanism for error-free repair of DNA double strand breaks.

218 Error-free repair of DNA double-strand breaks (DSBs) is

219 Homologous recombination (HR) mediates the error-free repair of DNA double-strand breaks to maintai

220 Fanconi anemia (FA) pathway, which promotes error-free repair of DNA double-strand breaks, is requir

221 merase II (Top2) cleavage complexes to allow error-free repair of DNA double-strand breaks, thereby c

222 These results reveal a role for HMGB1 in the error-free repair of DNA lesions.

223 BRCA2 tumour suppressor is essential for the error-free repair of double-strand breaks (DSBs) in DNA

224 process of homologous recombination promotes error-free repair of double-strand breaks and is essenti

225 The error-free repair of double-stranded DNA breaks by homol

226 notype indicates that they are important for error-free repair of spontaneous and induced DNA lesions

227 moval of UVC-induced lesions and facilitated error-free repair of TFO-ICLs in mouse fibroblasts.

228 ing maps are distorted by the error-prone or error-free repair of these uracils and by selection pres

229 divert cells towards error-prone instead of error-free repair pathways, dramatically increasing the

230 ologous recombination, which is typically an error-free repair process.

231 f the DSB ends if they are compatible (i.e., error-free repair) or sequence alteration upon rejoining

232 1 filament assembly and stability, promoting error-free repair.

233 Tdp1 and the 3'-phosphate by Tpp1 to mediate error-free repair.

234 human DNA polymerase-iota (Poliota) promotes error-free replication across 1-MeA.

235 polymerases, whereby pol II is necessary for error-free replication and pol V for error-prone replica

236 gh hydrogen bonding is clearly important for error-free replication by this Y-class DNA polymerase, o

237 astereomers of Me-PTEs at TX sites exhibited error-free replication bypass.

238 Human HLTF, implicated in error-free replication of damaged DNA and tumour suppres

239 NA polymerase (Pol) eta, which catalyzes the error-free replication of template thymine-thymine (TT)

240 ve site, and offer a basis for understanding error-free replication of the BP-derived stereoisomeric

241 quirement of yeast Polzeta for predominantly error-free replication past thymine glycol (Tg), a DNA l

242 ols), whereas Poleta promotes proficient and error-free replication through CPDs.

243 endent postreplication repair (PRR) in which error-free replication through the DNA lesion occurs by

244 reviously, we have shown that proficient and error-free replication through the gamma-HOPdG (gamma-hy

245 and Pol zeta function together in promoting error-free replication through the lesion, and based on

246 ic polymerases in its proficient ability for error-free replication through ultraviolet-induced cyclo

247 stages, respectively, are representative of error-free replication, with MeFapy-dG in the anti confo

248 ion fork progression and threaten timely and error-free replication.

249 ucts, which gives insights how Rev1 achieves error-free replication.

250 n and, while replication across alpha-dA was error-free, replicative bypass of alpha-dC and alpha-dG

251 The frequent k-mers constitute a reduced but error-free representation of the experiment, which can i

252 s, but constraints may emerge when immediate error-free responses are required and evolutionary or de

253 ing a published phylogenetic estimate is not error-free, retaining a full record of the provenance of

254 ould allow renewed attempt for repair by the error-free RNase H2-dependent pathway in vivo.

255 n of Pols kappa and zeta implicates a highly error-free role of Poleta in TLS opposite CPDs in mammal

256 ethidium bromide, as tools to facilitate the error-free self-assembly of DNA nanostructures.

257 to our language processing mechanisms is an error-free sequence of words.

258 family, where Multipass generates 20 % more error-free sequences than current state of the art metho

259 that significantly improves the fraction of error-free sequences.

260 allow generation of a set of high confidence error-free sequences.

261 cations of this process under assumptions of error-free sequencing and perfect mapping, using cytosin

262 sis by pol eta is likely to be predominantly error-free, since the probability of correct insertion a

263 e stability as it promotes repair of DSBs by error-free sister-chromatid recombination (SCR), thereby

264 magnification and quality, and analysis with error-free software, the VLA can be measured precisely a

265 The procedure discussed here enables error-free storage by protecting the information using e

266 The error-free structured PEC area was found to be significa

267 n elegant means for promoting proficient and error-free synthesis through N2-adducted guanines that o

268 Poliota and Polkappa promotes efficient and error-free synthesis through the HNE-dG adducts, in whic

269 ng correct dCMP opposite alpha-OH-PdG during error-free synthesis.

270 g is a week-long process that produces 5,188 error-free synthetic DNAs in a single run of NGS with a

271 ped TBIO method of PCR-based gene synthesis, error-free synthetic genes for the human protein kinases

272 ong or incomplete data, since it persists in error-free, synthetically produced datasets and does not

273 show that the yeast Rad5 protein can promote error-free template switching and replication past a DNA

274 trand DNA synthesis and subsequent bypass by error-free template switching.

275 or-prone translesion synthesis (TLS), and an error-free, template-switching pathway in Saccharomyces

276 e-derived adenine lesion (dA*); while mainly error-free, the identity of misincorporated bases is inf

277 on and orientation of the hairs is virtually error free, thus forming a nearly perfect parallel array

278 ions, analyzed the relative contributions of error-free TLS by Poleta and error-prone TLS by Poltheta

279 A would provide Poltheta the proficiency for error-free TLS in human cells.

280 purified Poltheta, it performs predominantly error-free TLS in human cells.

281 c-like mode, Poltheta performs predominantly error-free TLS in human cells.

282 ic TLS in yeast, Rev1 promotes predominantly error-free TLS opposite UV lesions in humans.

283 kappa and zeta function together and mediate error-free TLS, whereas in the other, poltheta functions

284 Whereas TS is mainly error-free, TLS can work in an error-prone manner and, a

285 om high-fidelity replicative DNA processing (error-free) to low-fidelity translesion DNA synthesis (e

286 When error-free tolerance is disrupted through deletion of MM

287 In the presence or absence of Mms2-dependent error-free tolerance, the catalytic dead strain of Rev1

288 sequent sequencing of the mCherry cDNA shows error-free transcription.

289 moderately increased levels, Rad26 promotes error-free transcriptional bypass and TC-NER of UV photo

290 d moderate eviction of Spt5 and promotion of error-free transcriptional bypass of DNA lesions by Rad2

291 d frequency regulation of Msn2 is limited to error-free transduction of signal identity, but not sign

292 greater latitude in promoting efficient and error-free translesion DNA synthesis through the diverse

293 ow that H2Bub1 normally functions to promote error-free translesion synthesis (TLS) mediated by DNA p

294 indicate that polymerase eta is involved in error-free translesion synthesis past some cisplatin add

295 xcision repair is generally considered to be error free, translesion synthesis can result in mutation

296 We also demonstrate simultaneous error-free transmission of two signals at different carr

297 nd the proportion of visits that resulted in error-free treatment plans.

298 tion, these approaches hindered designing an error free WGSA pipeline.

299 and retain only those DNA molecules that are error free with respect to the target.

300 upstream of the abasic lesion is replicated error-free; yet dramatically, once Dpo4 encounters the l