ライフサイエンスコーパス: erythritol

1 lipid levels over time in mosquitoes fed on erythritol.

2 evalonate and deuterium-labeled 2-C-methyl-D-erythritol.

3 en a choice was given but were not averse to erythritol.

4 or catabolism of d-threitol, l-threitol, and erythritol.

5 btained from bacteria grown on (13)C-labeled erythritol.

6 (250 mm) without concomitant accumulation of erythritol.

7 ), promoting threitol synthesis over that of erythritol.

8 lar weight non-electrolytes (malonamide-14C, erythritol-14C, D-arabinose-14C, and D-mannitol-14C) are

9 erythritol 4-phosphate (MEP) to 2-C-methyl-d-erythritol 2,4-cyclodiphosphate (cMEDP) in the MEP entry

10 The enzyme 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (MECDP) synthase catalyz

11 hylerythritol phosphate (MEP) and 2-C-methyl-erythritol 2,4-cyclodiphosphate (MEcPP), natural substra

12 yl-D-erythritol 2-phosphate into 2C-methyl-D-erythritol 2,4-cyclodiphosphate at catalytic rates of 19

13 hritol) and third (synthesis of 2-C-methyl-d-erythritol 2,4-cyclodiphosphate) steps.

14 onversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to MECDP, a highly unu

15 own genes of the non-mevalonate 2-C-methyl-D-erythritol 2-phosphate (MEP) pathway for synthesis of is

16 conversion of 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate into 2C-methyl-D-erythritol 2,4-c

17 linic acid, 1,3-dipetroselinin, 2-C-methyl-d-erythritol, 2-C-methyl-d-erythritol 4-O-beta-d-glucopyra

18 d on addition of the substrate, 2-C-methyl-D-erythritol-2, 4-cyclo-diphosphate.

19 ntermediate of the MEP pathway, 2-C-methyl-D-erythritol-2, 4-cyclodiphosphate, which is known to stim

20 he IspG-catalyzed conversion of 2-C-methyl-D-erythritol-2,4-cyclo-diphosphate into (E)-1-hydroxy-2-me

21 e synthase (GcpE/IspG) converts 2-C-methyl-D-erythritol-2,4-cyclodiphosphate (MEcPP) into (E)-4-hydro

22 s how the plastidial metabolite 2-C-methyl-D-erythritol-2,4-cyclopyrophosphate (MEcPP) orchestrates t

23 es not catalyze the formation of 2C-methyl-D-erythritol 3,4-cyclophosphate from 4-diphosphocytidyl-2C

24 for xylitol, mannitol, sorbitol, 15 mg/L for erythritol, 38 mg/L for maltitol and 91 mg/L for isomalt

25 phate (HMBPP), a product of the 2-C-methyl-D-erythritol 4- phosphate (MEP) pathway in bacteria that i

26 linin, 2-C-methyl-d-erythritol, 2-C-methyl-d-erythritol 4-O-beta-d-glucopyranoside and linalool.

27 hyl-D-erythritol is formed from 2-C-methyl-D-erythritol 4-phosphate (MEP) and CTP in a reaction catal

28 pD) catalyzes the conversion of 2-C-methyl-D-erythritol 4-phosphate (MEP) and cytidine triphosphate (

29 yzes the conversion of DXP into 2-C-methyl-D-erythritol 4-phosphate (MEP) by consecutive isomerizatio

30 nhibitor of the MVA-independent 2-C-methyl-D-erythritol 4-phosphate (MEP) isoprenoid pathway, unexpec

31 Most bacteria use the 2-C-methyl-D-erythritol 4-phosphate (MEP) pathway for the synthesis o

32 ounds are synthesized using the 2-C-methyl-D-erythritol 4-phosphate (MEP) pathway in many gram-negati

33 The 2-C-methyl-D-erythritol 4-phosphate (MEP) pathway leads to the biosyn

34 xy-D-xylulose 5-phosphate (DXP)/2-C-methyl-D-erythritol 4-phosphate (MEP) pathway of isoprenoid synth

35 hesised in chloroplasts via the 2-C-methyl-d-erythritol 4-phosphate (MEP) pathway.

36 supply of precursors through the 2C-methyl-D-erythritol 4-phosphate (MEP) pathway.

37 pathway and the plastid-associated 2C-methyl erythritol 4-phosphate (MEP) pathway.

38 sm of the reaction catalyzed by 2-C-methyl-d-erythritol 4-phosphate (MEP) synthase from Escherichia c

39 eductoisomerase (DXR, also known as methyl-d-erythritol 4-phosphate (MEP) synthase) is a NADPH-depend

40 The conversion of 2-C-methyl-d-erythritol 4-phosphate (MEP) to 2-C-methyl-d-erythritol

41 osphorylation of enzymes in the 2-C-methyl-d-erythritol 4-phosphate (MEP)/terpenoid and shikimate/phe

42 2-C-Methyl-D-erythritol 4-phosphate (MEP, 2) and 4-diphosphocytidyl-2

43 ctively, and plants, utilize the 2C-methyl-D-erythritol 4-phosphate (MEP, 5) pathway for the biosynth

44 rpene, monoterpene, triterpene, 2-C-methyl-D-erythritol 4-phosphate and mevalonate pathways.

45 deoxy-d-xylulose 5-phosphate to 2-C-methyl-d-erythritol 4-phosphate in the presence of NADPH.

46 o catalyze the transformation of 2C-methyl-D-erythritol 4-phosphate into 4-diphosphocytidyl-2C-methyl

47 biosynthesis, the conversion of 2C-methyl-d-erythritol 4-phosphate into its cyclic diphosphate proce

48 2-C-methyl-D-erythritol 4-phosphate is the first committed intermedia

49 hloroplastic methylerythritol 2-C-methyl-D: -erythritol 4-phosphate isoprenoid pathway.

50 ion as an electron donor for the 2C-methyl-D-erythritol 4-phosphate pathway and is a potential drug t

51 ncoding enzymes involved in the 2-C-methyl-d-erythritol 4-phosphate pathway and the biosynthesis of s

52 ase in transcript levels of the 2-C-methyl-D-erythritol 4-phosphate pathway enzyme 1-deoxy-D-xylulose

53 nzymes involved in the essential 2C-methyl-D-erythritol 4-phosphate pathway of isoprenoid biosynthesi

54 hosphoantigens derived from the 2-C-methyl-d-erythritol 4-phosphate pathway of isoprenoid synthesis.

55 xenobiotics; methanogenesis; and 2-methyl-d-erythritol 4-phosphate pathway-mediated biosynthesis of

56 o be the key step in regulating 2-C-methyl-D-erythritol 4-phosphate substrate flux in kiwifruit.

57 izes the immediate precursor of 2-C-methyl-D-erythritol 4-phosphate.

58 sphite dianion, d-glycerol 3-phosphate and d-erythritol 4-phosphate.

59 nthesized via the chloroplastic 2-C-methyl-d-erythritol 4-phosphate/1-deoxy-d-xylulose 5-phosphate pa

60 We synthesized five D-MEP analogues-D-erythritol-4-phosphate (EP), D-3-methylthrietol-4-phosph

61 ipt levels of several plastidic 2-C-methyl-d-erythritol-4-phosphate (MEP) pathway genes, geranylgeran

62 ct herbivory down-regulates the 2-C-methyl-D-erythritol-4-phosphate (MEP) pathway in Arabidopsis (Ara

63 The plastidic 2-C-methyl-D-erythritol-4-phosphate (MEP) pathway is one of the most

64 ted by the mevalonate (MVA) and 2-C-methyl-d-erythritol-4-phosphate (MEP) pathways, which have been e

65 tol metabolism involves phosphorylation to L-erythritol-4-phosphate by the kinase EryA and oxidation

66 e inhibitors of Plasmodium spp. 2-C-methyl-D-erythritol-4-phosphate cytidyltransferase (IspD), the th

67 Escherichia coli 2-C-methyl-D-erythritol-4-phosphate cytidyltransferase (YgbP or IspD)

68 (HMBPP), an intermediate in the 2-C-methyl-d-erythritol-4-phosphate pathway used by microbes, and iso

69 2-C-Methyl-D-erythritol-4-phosphate synthase (MEP synthase) catalyzes

70 A pathway, and in plastids from 2-C-methyl-d-erythritol-4-phosphate through the MEP pathway.

71 een applied to a new synthesis of 2-methyl-D-erythritol, a branched five-carbon sugar of importance t

72 Use of erythritol, a low-calorie sweetener, has increased recen

73 hosphate from 4-diphosphocytidyl-2C-methyl-D-erythritol, a side reaction catalyzed in vitro by the Is

74 % (NIR) and 95 % (MIR) were achieved, while erythritol achieved EFRs of 96 % (NIR) and 98 % (MIR).

75 tudies of sugar alcohols mannitol, sorbitol, erythritol, adonitol, arabitol, galactitol, and xylitol

76 instrumentation (SI) with adjunctive use of erythritol airflowing (EAF) compared to SI alone in the

77 ther by the type of growth on Casamino Acids-erythritol-albumin agar and by micromorphological differ

78 of catalyzing the conversion of erythrose to erythritol: alcohol dehydrogenase 1 (ADH1) and sorbitol

79 Our results suggest the possibility of using erythritol alone or in combination with sucrose as a com

80 examined the commonly used sugar substitute erythritol and atherothrombotic disease risk.

81 The combination of erythritol and chlorhexidine displayed stronger antimicr

82 this study, a new formulation consisting of erythritol and chlorhexidine is compared with the standa

83 tigate potential causal associations between erythritol and coronary artery disease (CAD), BMI, waist

84 However, only erythritol and highly concentrated xylitol induced morta

85 nient method for the synthesis of 2-methyl-D-erythritol and is expected to be useful for generating i

86 se may contribute to the association between erythritol and obesity observed in young adults.

87 One group was negative for I-erythritol and ribitol and included all the isolates bel

88 e remaining three groups were positive for I-erythritol and ribitol and were grouped within Nocardia

89 ructose-1,6-bisphosphatases grew normally on erythritol and that EryC, which was assumed to be a dehy

90 hosphate into 4-diphosphocytidyl-2C-methyl-D-erythritol and the conversion of 4-diphosphocytidyl-2C-m

91 Formulations containing erythritol and xylitol should be further investigated un

92 synthesis of 4-diphosphocytidyl-2-C-methyl d-erythritol) and third (synthesis of 2-C-methyl-d-erythri

93 nted by sugar alcohols (notably mannitol and erythritol), and amino acids including phenylalanine and

94 glycoside) to 725.6 mg/100 g dm (puree with erythritol), and the content of these compounds strongly

95 by glycerol-like osmolytes such as xylitol, erythritol, and propanediol.

96 sucrose), four polyols (glycerol, mannitol, erythritol, and sorbitol), five amino acids (glycine, al

97 was detected, as well as elevated amounts of erythritol, arabitol, and ribitol in the plasma of affec

98 Elevated urinary excretion of erythritol, arabitol, ribitol, and pent(ul)ose-5-phospha

99 Studies assessing the long-term safety of erythritol are warranted.

100 We now have to recognize erythritol as a candidate for food allergen, and to be c

101 jelly product for diet supplement containing erythritol as a major component.

102 oca starch served as the glucosyl donor, and erythritol as the acceptor.

103 Accordingly, growth on erythritol as the sole C source should require aldolase

104 and compared to the corresponding bis(diol), erythritol, as well as the corresponding mono(alpha-hydo

105 hese associations remain unknown because the erythritol biosynthesis pathway, particularly the enzyme

106 vide clues to the preferential metabolism of erythritol by Brucella and its role in pathogenicity.

107 Efficient erythritol catabolism under conditions that promote thre

108 (MEP, 2) and 4-diphosphocytidyl-2-C-methyl-D-erythritol (CDPME, 3) are metabolites in the MEP pathway

109 anium disks and air polished with glycine or erythritol-chlorhexidine powders.

110 Air polishing with erythritol-chlorhexidine seems to be a viable alternativ

111 Canalicular bile flow, as measured by [14C]erythritol clearance after functional nephrectomy, was s

112 21-fold (95% CI: 19.84, 21.41) higher blood erythritol compared with participants with lower HbA1c (

113 ce interval (CI): 13.27, 16.25] higher blood erythritol compared with participants with stable adipos

114 Glycerophosphocholines, erythritol, creatinine, hexadecanoic acid, and glutamine

115 idial retrograde signaling metabolite methyl-erythritol cyclodiphosphate (MEcPP) and the defense horm

116 Based on utilization of I-erythritol, D-glucitol, i-myo-inositol, D-mannitol, and

117 agine, L-Aspartic Acid, L- Glutamic Acid, m- Erythritol, D-Melezitose, D-Sorbitol) triggered the fung

118 ingredients, with the prebiotic activity of erythritol derivatives being influenced by the length of

119 By reacting erythritol dicarbonate with bio-based diamines, fully bi

120 of the bovine reproductive tract are rich in erythritol during the latter stages of pregnancy, and th

121 In this study, maltotriosyl-erythritol (EG(3)) was synthesized as a novel prebiotic

122 At physiological levels, erythritol enhanced platelet reactivity in vitro and thr

123 ht be responsible for the negative impact of erythritol feeding in mosquitoes.

124 Therefore, endogenous production of erythritol from glucose may contribute to the associatio

125 eoxyribonic acid; 3,4-dihydroxybutyric acid; erythritol; gluconic acid; and ribose were validated in

126 cid, heat, and digestive enzymes compared to erythritol glucosides (EG(1)(-)(2)) and significantly pr

127 ation of the growth medium with 2-C-methyl-D-erythritol has been shown to complement disruptions in t

128 lant-based sugar substitutes such as stevia (erythritol) have been shown to affect lifespan in other

129 ts are determined against the known k(OH) of erythritol in pure water.

130 formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol in the presence of MEP and CTP.

131 not find supportive evidence that increased erythritol increases CAD (b = -0.033 +/- 0.02, P = 0.14;

132 id not find supportive evidence from MR that erythritol increases cardiometabolic disease.

133 oral challenge test in the hospital, 3 g of erythritol induced remarkable coughing, urticaria, edema

134 ve pilot intervention study ( NCT04731363 ), erythritol ingestion in healthy volunteers (n = 8) induc

135 that prevented the transport of 2-C-methyl-D-erythritol into the cell.

136 Erythritol is a natural sugar alcohol, with the molecula

137 Erythritol is an important nutrient for several alpha-2

138 Our findings reveal that erythritol is both associated with incident MACE risk an

139 The low-calorie sweetener erythritol is endogenously produced from glucose through

140 MEP pathway, 4-diphosphocytidyl-2-C-methyl-D-erythritol is formed from 2-C-methyl-D-erythritol 4-phos

141 Erythritol is of medical interest because elevated plasm

142 of pregnancy, and the ability to metabolize erythritol is thought to be important to the virulence o

143 prolylhydroxyproline) is a dipeptide, and 1 (erythritol) is a sugar alcohol.

144 thritol synthesis (reduction of erythrose to erythritol), is not characterized.

145 ked and sustained (>2 d) increases in plasma erythritol levels well above thresholds associated with

146 he determination of low calories sweeteners (erythritol, mannitol, maltitol, sorbitol, isomalt and xy

147 ate the effect of sucrose replacer mixtures (erythritol, mannitol, or tagatose in combination with in

148 MR indicates erythritol may decrease BMI (b = -0.04 +/- 0.018, P = 0.

149 significant variants from three cohorts with erythritol measurement.

150 Erythritol metabolism involves phosphorylation to L-eryt

151 zed in isoprenoid biosynthesis, 2-C-methyl-D-erythritol must be phosphorylated.

152 e (Equal), and saccharin (Sweet'N Low), only erythritol negatively affected mosquito longevity and fe

153 had statistically significantly higher blood erythritol [P < 0.001, false discovery rate (FDR) = 0.04

154 HMBPP) in the penultimate step of the methyl-erythritol phosphate (MEP) pathway for isoprene biosynth

155 The methyl-d-erythritol phosphate (MEP) pathway has emerged as an int

156 IspH, an enzyme in the methyl erythritol phosphate pathway of isoprenoid synthesis, is

157 hate, HDMAPP), an intermediate in the methyl erythritol phosphate pathway, and (E)-[4-(2)H]HDMAPP wer

158 hich are produced in plastids via the methyl erythritol phosphate pathway, geraniol biosynthesis in r

159 SORD catalyze the conversion of erythrose to erythritol, pointing to novel roles for two dehydrogenas

160 comparable D90 value, the sample containing erythritol-polydextrose mixture resulted in a similar (P

161 confirmed SORD contributes to intracellular erythritol production in human A549 lung cancer cells, w

162 These findings suggest that erythritol-receptor products formed via AMase-catalyzed

163 thyl-2,3-O-isopropylidene-tartrate, and meso-erythritol, respectively.

164 including pseudogenization events linked to erythritol response, the supposed determinant of the pat

165 2-7% for 2, 3-butanediol, ethanol, glycerol, erythritol, rhamnose, arabitol, sorbitol, galactitol, ma

166 ant by genetic complementation abolished the erythritol-specific growth defect exhibited by this stra

167 Of the four sugar substitutes tested, erythritol (Stevia), sucralose (Splenda), aspartame (Equ

168 ctive effects of some additives (palm sugar, erythritol, steviol glycoside, xylitol and inulin) on th

169 ing 30% increase in the biliary clearance of erythritol suggested that the choleresis was primarily o

170 nnose biosynthesis pathway in females fed on erythritol, suggesting that N-linked glycosylation might

171 talyzed by a 4-diphosphocytidyl-2-C-methyl-D-erythritol synthase (IspD).

172 arly the enzyme catalyzing the final step of erythritol synthesis (reduction of erythrose to erythrit

173 Erythritol tetranitrate (ETN) is an explosive that recen

174 this strain was cultured in the presence of erythritol than that required when it was cultured in th

175 xperiments and through in vivo conversion of erythritol to erythronate in stable isotope-assisted dri

176 ated by the observation that the addition of erythritol to low-iron cultures of B. abortus 2308 stimu

177 yrosol, phenylethyl alcohol, 2,3-butanediol, erythritol, tryptophol, putrescine, cadaverine, 3-phenyl

178 display wild-type growth in the presence of erythritol under iron-limiting conditions is due to a de

179 tion and efficient growth in the presence of erythritol under low-iron conditions.

180 ortus 2308, when cultured in the presence of erythritol under low-iron conditions.

181 nant human ADH1 and SORD reduce erythrose to erythritol, using NADPH as a co-factor, and cell culture

182 HBA production and growth in the presence of erythritol was further substantiated by the observation

183 Prick test with erythritol was negative even at 300 mg/ml, which was alm

184 Erythritol was shown to be synthesized endogenously from

185 ains of RMC26 unable to grow on 2-C-methyl-D-erythritol were incubated in buffer containing mevalonat

186 ls of multiple polyol sweeteners, especially erythritol, were associated with incident (3 year) risk

187 hod to verify the purity and authenticity of erythritol, xylitol, and stevia using near- and mid-infr

188 ies and sound speeds of aqueous solutions of Erythritol, Xylitol, Sorbitol, and Maltitol were measure

189 ent natural sweeteners (sucrose, palm sugar, erythritol, xylitol, steviol glycoside, Luo Han Kuo), an