ライフサイエンスコーパス: erythropoiesis

1 critical to normal red cell differentiation (erythropoiesis).

2 modulates hepcidin expression, and regulates erythropoiesis.

3 othelial cells, resulting in iron-restricted erythropoiesis.

4 expression in individual cells during human erythropoiesis.

5 asis when inflammation inhibits steady-state erythropoiesis.

6 eviously unappreciated regulator of terminal erythropoiesis.

7 -mediated regulation of iron homeostasis and erythropoiesis.

8 ruction of erythroblasts causing ineffective erythropoiesis.

9 ng heme and translation in the regulation of erythropoiesis.

10 or cells that are distinct from steady-state erythropoiesis.

11 nes critical to cellular processes including erythropoiesis.

12 of key erythroid genes and modulated ex vivo erythropoiesis.

13 and trafficking of the CD47 isoforms during erythropoiesis.

14 rdinated expression of these proteins during erythropoiesis.

15 d demonstrating that RBPMS is a regulator of erythropoiesis.

16 tatus and based on health outcomes, not just erythropoiesis.

17 ential for gender specific EPO action beyond erythropoiesis.

18 tin-mediated JAK2 signaling is essential for erythropoiesis.

19 gakaryocyte lineage but downregulated during erythropoiesis.

20 l regulatory dynamics during murine terminal erythropoiesis.

21 hting a key function for this protein during erythropoiesis.

22 GATA1 is a critical regulator of erythropoiesis.

23 eriods and fail to respond to TH by enhanced erythropoiesis.

24 the initial activation of the Gata1 gene and erythropoiesis.

25 n prolonged relative to that of actin during erythropoiesis.

26 ellular stores and subsequent stimulation of erythropoiesis.

27 c syndromes are characterised by ineffective erythropoiesis.

28 ESAs have effects beyond erythropoiesis.

29 iron atoms every second to maintain adequate erythropoiesis.

30 cidin expression to supply adequate iron for erythropoiesis.

31 in the development of anemia and ineffective erythropoiesis.

32 cidin augments iron delivery for intensified erythropoiesis.

33 th other tissues but ultimately is unique to erythropoiesis.

34 hepatic EPO regulation mechanism stimulating erythropoiesis.

35 uggest the involvement of new genes in human erythropoiesis.

36 e splicing program occurring during terminal erythropoiesis.

37 genic growth factor, in the transition to FL erythropoiesis.

38 inflammatory cues, and iron requirements for erythropoiesis.

39 f erythroblast enucleation during definitive erythropoiesis.

40 ovel strategies for augmenting or inhibiting erythropoiesis.

41 s erythroid lineage competence and effective erythropoiesis.

42 d regulator that inhibits hepcidin in stress erythropoiesis.

43 on toward megakaryopoiesis at the expense of erythropoiesis.

44 s several species, and active in stimulating erythropoiesis.

45 cts of Ex12 signaling on megakaryopoiesis or erythropoiesis.

46 estigate the role of renal epithelial HIF in erythropoiesis.

47 el hematopoietic function of VEGF-C in fetal erythropoiesis.

48 uclear opening formation throughout terminal erythropoiesis.

49 signals that are distinct from steady-state erythropoiesis.

50 rt, by the miR-144 targeting of Dicer during erythropoiesis.

51 of GATA1s promoted megakaryopoiesis, but not erythropoiesis.

52 ecursors (EPs) and is essential for terminal erythropoiesis.

53 serum LDH level, consistent with ineffective erythropoiesis.

54 role in mediating testosterone's effects on erythropoiesis.

55 lso linked to iron economy, inflammation and erythropoiesis.

56 factors governing hemoglobin assembly during erythropoiesis.

57 jor contributing factor is the impairment of erythropoiesis.

58 ed for bone loss accompanying EPO-stimulated erythropoiesis.

59 endogenous iron deposits and stimulation of erythropoiesis.

60 Erythropoietin (EPO) is a key regulator of erythropoiesis.

61 ns induced dyserythropoiesis and ineffective erythropoiesis.

62 ses Dicer in a negative-feedback loop during erythropoiesis.

63 bone marrow and fetal liver, which disrupts erythropoiesis.

64 iron and heme play central roles in terminal erythropoiesis.

65 erythroid progenitor pool and robust splenic erythropoiesis.

66 ion of a network of genes required for human erythropoiesis.

67 sion, resulting in apoptosis and ineffective erythropoiesis.

68 3K36M developed severe anaemia with arrested erythropoiesis, a marked haematopoietic stem cell defect

69 ntial for erythrocyte regeneration in stress erythropoiesis, a vital process in pathologies, includin

70 n receptor (GATA-1-ER) and therefore undergo erythropoiesis after beta-estradiol (E(2)) addition.

71 fate decisions, but how these changes affect erythropoiesis, an essential process in blood cell forma

72 growth in vitro is associated with elevated erythropoiesis, an obligate step towards erythroid recov

73 din induction contributes to iron-restricted erythropoiesis and anemia in chronic inflammatory diseas

74 To study erythropoiesis and anemia, one must have a firm foundati

75 on repressed Gata2 transcription and induced erythropoiesis and apoptosis of HSPCs.

76 there is a need to better understand stress erythropoiesis and changes in iron metabolism during pre

77 s on how Plasmodium parasites interfere with erythropoiesis and contribute to anemia in malaria patie

78 ing an important regulatory role for EMP3 in erythropoiesis and control of cell production.

79 eukemogenic CM fusion protein disrupts adult erythropoiesis and creates stress-resistant preleukemic

80 used beta-thalassemia, minihepcidin improves erythropoiesis and does not alter the beneficial effect

81 ur results reveal a pivotal role for ETO2 in erythropoiesis and globin gene switching through its rep

82 depletion phenotypes in zebrafish primitive erythropoiesis and granulocytic differentiation in cultu

83 he involvement of Fe-S cluster biogenesis in erythropoiesis and hematopoiesis and define HSCB as a CS

84 portant roles of H2AX in late-stage terminal erythropoiesis and hematopoietic stem cell function.

85 anscriptional co-repressor ETO2 during early erythropoiesis and hemoglobin switching is unclear.

86 free alpha-globin chains causing ineffective erythropoiesis and hemolysis.

87 ing candidate for the link between increased erythropoiesis and hepcidin suppression.

88 on the brain, stem cells, and the process of erythropoiesis and identifies gaps in our knowledge of w

89 of ASXL1 in cord blood CD34(+) cells reduced erythropoiesis and impaired erythrocyte enucleation.

90 Our study unveils a key role for ASXL1 in erythropoiesis and indicates that ASXL1 loss hinders ery

91 in inflammasome-deficient larvae, enforcing erythropoiesis and inhibiting myelopoiesis.

92 Erythropoiesis and iron deficiency suppress hepcidin via

93 ersible epigenetic modifications during both erythropoiesis and iron deficiency.

94 eted factors that exert a negative effect on erythropoiesis and iron use.

95 on conditions that might promote ineffective erythropoiesis and iron-loading anemia.

96 protein hormone that is essential for normal erythropoiesis and is predominantly synthesized by perit

97 The adult kidney plays a central role in erythropoiesis and is the main source of erythropoietin

98 l for human studies of normal and disordered erythropoiesis and its effect on iron homeostasis.

99 Hematopoietic ageing involves declining erythropoiesis and lymphopoiesis, leading to frequent an

100 ta show that NR4A1 expression by MPPS limits erythropoiesis and megakaryopoeisis, permitting developm

101 gical pathways, allowing regulators of human erythropoiesis and modifiers of blood diseases to be def

102 a human disease with detrimental effects to erythropoiesis and neurodevelopment.

103 This work reveals modular regulation of erythropoiesis and offers a new strategy for overcoming

104 ntral and systemic metabolism as well as for erythropoiesis and oxygen transport.

105 eta-globin synthesis, leading to ineffective erythropoiesis and RBCs with a short life span.

106 Most children showed an adequate erythropoiesis and recovered from anemia within one mont

107 at synergistically facilitates apoptosis and erythropoiesis and restrains adverse proliferation, indi

108 Testosterone stimulates iron-dependent erythropoiesis and suppresses hepcidin.

109 efficiency is dynamically controlled during erythropoiesis and that enrich for target sites of RNA-b

110 We first present a review of erythropoiesis and then describe our approach to cancer-

111 o synthesis led to its secretion, to splenic erythropoiesis and to dramatic erythrocytosis.

112 MPN mouse models correlated with hyperactive erythropoiesis and was due to a combination of elevated

113 We identified a new modular organization of erythropoiesis and, for the first time, demonstrate that

114 cluded an increase in T cell homing factors, erythropoiesis, and adipogenesis.

115 by hepcidin, d) erythropoietin regulation of erythropoiesis, and e) liver uptake of NTBI.

116 enomegaly, microcytic anemia, extramedullary erythropoiesis, and increased hemophagocytic macrophages

117 the underlying chain imbalance, ineffective erythropoiesis, and iron dysregulation, with several age

118 s characterised by haemolysis and inadequate erythropoiesis, and is associated with dysregulated infl

119 kemia and is required for HSC specification, erythropoiesis, and megakaryopoiesis, is a negative regu

120 lammation, angiogenesis, glucose metabolism, erythropoiesis, and other physiological activities.

121 mia signature indicated deregulation of host erythropoiesis, and the lung inflammation signature was

122 (Slc25a37), is highly expressed in sites of erythropoiesis, and whole-body Slc25a37 deletion leads t

123 ssemia, minihepcidin ameliorates ineffective erythropoiesis, anemia, and iron overload.

124 ntrol oxygen supply to tissues by regulating erythropoiesis, angiogenesis and vascular homeostasis.

125 r mechanisms by which iron and heme regulate erythropoiesis are not completely understood.

126 mechanisms of chromatin condensation during erythropoiesis are unclear.

127 Drugs that enhance erythropoiesis are urgently required to decrease transfu

128 ion of Erfe slightly ameliorated ineffective erythropoiesis, as indicated by reduced spleen index, re

129 fibroblast-like cells are critical for adult erythropoiesis, as they are the main source of erythropo

130 partially compensated by avid extramedullary erythropoiesis at all erythroid stages in the spleen the

131 f hemochromatosis and induce iron-restricted erythropoiesis at higher doses.

132 lidomide acted early by transiently delaying erythropoiesis at the burst-forming unit-erythroid/colon

133 , AKAP10, regulates heme biosynthesis during erythropoiesis at the outer mitochondrial membrane.

134 terial burdens, implying that extramedullary erythropoiesis benefits the host.

135 VIT-2763 not only improved erythropoiesis but also corrected the proportions of mye

136 iologically in iron deficiency and increased erythropoiesis but is pathologic in thalassemia and hemo

137 .sTfR may be useful to assess iron-deficient erythropoiesis, but inflammation influences its interpre

138 teract to regulate chromatin architecture in erythropoiesis, but the mechanistic basis for this regul

139 e important for effective iron recycling and erythropoiesis, but they also play a crucial role in wou

140 udy, we have demonstrated that LPA activates erythropoiesis by activating the LPA 3 receptor subtype

141 Erythropoietin (EPO) regulates erythropoiesis by binding to erythropoietin receptor (Ep

142 1 represses mitochondrial respiration during erythropoiesis by inhibiting the production of Cox10.

143 -EPO module is coupled to late EPO-dependent erythropoiesis by megakaryocyte (Mk) signals.

144 investigated the role of O-GlcNAcylation in erythropoiesis by using G1E-ER4 cells, which carry the e

145 tisense oligonucleotides [ASOs]) or increase erythropoiesis (by erythropoietin [EPO] administration o

146 tween FGF23 regulation, iron homeostasis and erythropoiesis can be leveraged to devise novel therapeu

147 ain erythroid homeostasis until steady-state erythropoiesis can resume.

148 nisms have been proposed, the means by which erythropoiesis causes hepcidin suppression have been unc

149 se genetic background led to defective fetal erythropoiesis, characterized by anemia and lack of enuc

150 e alpha/beta-globin chain ratio, ineffective erythropoiesis, chronic haemolytic anaemia, compensatory

151 They belong to the wide group of ineffective erythropoiesis conditions that mainly result in monoline

152 in suppression in the setting of ineffective erythropoiesis contributes to iron-loading anemias such

153 , the estimated prevalence of iron-deficient erythropoiesis decreased by 4.4-14.6 and 0.3-9.5 percent

154 stration of IL-33 in healthy mice suppressed erythropoiesis, decreased hemoglobin expression, and cau

155 n exhibit rapid RBC turnover, with increased erythropoiesis, dramatically shortened RBC lifespan, and

156 Insufficient erythropoiesis due to increased demand is usually met by

157 y increased RBC turnover and higher rates of erythropoiesis during infection.

158 dback mechanism of erythropoietin-stimulated erythropoiesis during iron/heme deficiency.

159 yb However, adtrp1 knockdown does not affect erythropoiesis during primitive hematopoiesis (no effect

160 etter quality and efficiency of HbF-enriched erythropoiesis elevated hemoglobin using fewer reticuloc

161 X did not affect the early stage of terminal erythropoiesis, enucleation was decreased.

162 In contrast, definitive erythropoiesis failed and the mice died by E16.5, with p

163 to allow effective erythropoiesis, show that erythropoiesis fails when heme is excessive, and emphasi

164 Having no apparent effect on primitive erythropoiesis, FLKO mice show significant enhancement o

165 owever, persistent increased and ineffective erythropoiesis, for example in thalassemia, results in s

166 or beta (TGF beta) superfamily inhibitors of erythropoiesis, giving rise to a promising new investiga

167 macrophages in enhancing baseline and stress erythropoiesis has been emphasized over several decades,

168 An effect of thyroid hormone (TH) on erythropoiesis has been known for more than a century bu

169 ion and down-regulation of Pu.1 during early erythropoiesis have not been defined.

170 at TSPO deficiency does not adversely affect erythropoiesis, heme biosynthesis, bioconversion of ALA

171 or cell lines to examine the role of TSPO in erythropoiesis, heme levels, PPIX biosynthesis, phototox

172 odily function with well-documented roles in erythropoiesis, hemostasis, and inflammation.

173 alphaP and mTORC1, to circumvent ineffective erythropoiesis, highlighting heme and translation in the

174 ganese, and zinc) support iron's function in erythropoiesis, how these nutrients interact remains, to

175 a is a disorder characterized by ineffective erythropoiesis (IE), anemia, splenomegaly, and systemic

176 isorder that is characterized by ineffective erythropoiesis (IE), leading to anemia and abnormal iron

177 coordinated by HRI to circumvent ineffective erythropoiesis (IE).

178 thropoietin (EPO) levels, and extramedullary erythropoiesis in a process independent of Salmonella pa

179 monstrated dyserythropoiesis and inefficient erythropoiesis in all patients.

180 ed for inflammation-dependent suppression of erythropoiesis in BM.

181 Conversely, SIX1 knockout impaired erythropoiesis in both cell types.

182 We propose that NLK mediates aberrant erythropoiesis in DBA and is a potential target for ther

183 en species production, account for defective erythropoiesis in DBA.

184 plain the ineffective (early termination of) erythropoiesis in Diamond Blackfan anemia and del(5q) my

185 l hemoglobin expression was inhibited during erythropoiesis in embryonic day 13.5 and embryonic day 1

186 We reveal physiological erythropoiesis in fetal skin and the presence of mast ce

187 osterone treatment stimulates splenic stress erythropoiesis in iron-replete as well as iron-deficient

188 t only of definitive, but also of primitive, erythropoiesis in mammals.

189 al step toward chromatin condensation during erythropoiesis in mice.

190 ilization of liver iron stores during stress erythropoiesis in mice.

191 sts and bone loss accompanies EPO-stimulated erythropoiesis in mice.

192 errone and leads to expanded but inefficient erythropoiesis in murine bone marrow and an increase in

193 ggest that nutritional vitamin D may enhance erythropoiesis in settings of 25-hydroxy vitamin D (25(O

194 accompanied by an alleviation of ineffective erythropoiesis in Th3/(+) mice.

195 l in ameliorating the anemia and ineffective erythropoiesis in thalassemias.

196 found that inflammation also induced stress erythropoiesis in the absence of hypoxia.

197 re, despite their inhibition of steady-state erythropoiesis in the bone marrow, the proinflammatory c

198 Impaired erythropoiesis in the deletion 5q (del(5q)) subtype of m

199 the mechanisms contributing to the impaired erythropoiesis in the setting of reduced kidney function

200 mice despite the presence of extramedullary erythropoiesis in this tissue.

201 ivo in Drosophila hematopoiesis and in human erythropoiesis in vitro Using Drosophila genetics, we sh

202 We found that efficient stress erythropoiesis in vivo requires E2F-2, and we also ident

203 3 also suppressed erythropoietin-accelerated erythropoiesis in vivo.

204 demonstrated some aspects of iron-restricted erythropoiesis, including increased zinc protoporphyrin

205 ate, generating cells at different stages of erythropoiesis, including terminally differentiated nucl

206 propose a model of TFR2's function in murine erythropoiesis, indicating that deficiency in this recep

207 27a and -24 expression induces apoptosis and erythropoiesis, inhibits adverse growth and partly relie

208 Mammalian erythropoiesis involves chromatin condensation that is i

209 Macrocytic anemia with abnormal erythropoiesis is a common feature of megaloblastic anem

210 lator of iron homeostasis, is repressed when erythropoiesis is acutely stimulated by erythropoietin (

211 Stress erythropoiesis is best characterized in the mouse, where

212 Stress erythropoiesis is best understood in mice where it is ex

213 This stress-induced erythropoiesis is distinct from basal red blood cell gen

214 ance of down-regulation of Runx1 and Pu.1 in erythropoiesis is further supported by genome-wide analy

215 Normal erythropoiesis is highly regulated by the zinc finger tr

216 In contrast, decreased erythropoiesis is not an intrinsic property of aged HSCs

217 Steady-state erythropoiesis is primarily homeostatic, producing new e

218 He concluded that erythropoiesis is regulated by a humoral factor rather t

219 Hepcidin levels are suppressed when erythropoiesis is stimulated, for example following acut

220 Erythropoiesis is the complex, dynamic, and tightly regu

221 Although EKLF's function during early erythropoiesis is well studied, its role during terminal

222 widespread environmental toxicant, inhibits erythropoiesis likely through replacing zinc within the

223 unction and redistribute endogenous iron for erythropoiesis may offer additional options.

224 y regulate diverse gene groups during normal erythropoiesis, misregulation of which could be responsi

225 ompletely reversed ID anemia and ineffective erythropoiesis of Hri(-/-) , eAA, and Atf4(-/-) mice by

226 The defective terminal erythropoiesis of lineage-negative bone marrow cells of

227 hematopoietic lineage in mice does not alter erythropoiesis or erythroid precursor cell frequency und

228 definitive hematopoiesis, but not primitive erythropoiesis or vasculogenesis.

229 uction (a regenerative anemia or ineffective erythropoiesis) or increased destruction, and define par

230 n iron-deficient mice because of ineffective erythropoiesis possibly due to erythropoietin resistance

231 s the function of a key regulatory factor in erythropoiesis, producing effects functionally similar t

232 th a t(1/2) of 59 days, corresponding to the erythropoiesis rate in humans.

233 -Thalassemia is characterized by ineffective erythropoiesis, reduced production of erythrocytes, anem

234 through which glucocorticoids regulate human erythropoiesis remain poorly understood.

235 ts with MDS or MDS/MPN, the role of ASXL1 in erythropoiesis remains unclear.

236 SIX1 stimulation of erythropoiesis required GATA1, as SIX1 overexpression fa

237 not survive post birth due to aberrations in erythropoiesis resulting from an arrest in development a

238 eukin (IL)-1beta, alter iron homeostasis and erythropoiesis, resulting in anemia, but whether inhibit

239 ubiquitin-conjugating enzyme induced during erythropoiesis, results in anemia.

240 During early erythropoiesis, Runx1 and Pu.1 levels decline, and chrom

241 nto how heme is regulated to allow effective erythropoiesis, show that erythropoiesis fails when heme

242 ated with downregulation of Nrf2-related and erythropoiesis signatures by whole-blood transcriptomics

243 were compared with estimated iron-deficient erythropoiesis (sTfR concentration >8.3 mg/L): 1) the ex

244 e the estimated prevalence of iron-deficient erythropoiesis.sTfR may be useful to assess iron-deficie

245 re conducted prior to current approaches for erythropoiesis stimulating agent (ESA) drug dosing guide

246 beling was applied for the first time to the erythropoiesis stimulating agent (ESA) products, which f

247 ed reactively and resulted in lower doses of erythropoiesis-stimulating agent being administered.

248 Addition of an erythropoiesis-stimulating agent could improve response

249 lower-risk myelodysplastic syndromes in whom erythropoiesis-stimulating agent therapy is not effectiv

250 The median monthly dose of an erythropoiesis-stimulating agent was 29,757 IU in the hi

251 cluded death, infection rate, and dose of an erythropoiesis-stimulating agent.

252 ed with non-iron-based phosphate binders and erythropoiesis-stimulating agents (ESA) to receive 24 we

253 Erythropoiesis-stimulating agents (ESAs) are commonly us

254 ho are on hemodialysis are hyporesponsive to erythropoiesis-stimulating agents (ESAs) because of anem

255 n supplementation alone and as an adjunct to erythropoiesis-stimulating agents (ESAs) compared with E

256 safety of intravenous (IV) iron products and erythropoiesis-stimulating agents (ESAs) have resulted i

257 Small studies showed that erythropoiesis-stimulating agents (ESAs) improve subject

258 m (PPS) and changes to dosing guidelines for erythropoiesis-stimulating agents (ESAs) in 2011 appear

259 ed controlled trials assessing the effect of erythropoiesis-stimulating agents (ESAs) in critically i

260 e to high doses or a high cumulative dose of erythropoiesis-stimulating agents (ESAs) may contribute

261 odysplastic syndromes (MDS) are treated with erythropoiesis-stimulating agents (ESAs), with a respons

262 ying AI, the combination of iron therapy and erythropoiesis-stimulating agents can improve anemia in

263 was refractory to or unlikely to respond to erythropoiesis-stimulating agents or who had discontinue

264 d from myelodysplastic syndromes, relying on erythropoiesis-stimulating agents to cope with anemia, a

265 g current first-line therapies, such as with erythropoiesis-stimulating or hypomethylating agents.

266 igh circulating ERFE in conditions of stress erythropoiesis, such as in patients with beta-thalassemi

267 n the estimated prevalence of iron-deficient erythropoiesis than did the regression approach.

268 y be an effective treatment for disorders of erythropoiesis that are driven by aberrant EPO levels.

269 F1) is a master transcriptional regulator of erythropoiesis that is mutated in a subset of these anem

270 Cyclin ET74AT393A mice develop ineffective erythropoiesis that resembles early-stage human myelodys

271 Thus, heme and translation regulate erythropoiesis through 2 key signaling pathways, ISR and

272 eased after Day 7 correlating with increased erythropoiesis through adequate erythropoietin stimulati

273 roxylase inhibitor that promotes coordinated erythropoiesis through HIF-mediated transcription.

274 gest that inflammatory signals induce stress erythropoiesis to maintain erythroid homeostasis when in

275 s regulate self signaling, as is relevant to erythropoiesis, to clearance of rigid RBCs after blood s

276 semia and polycythemia vera (PV), disordered erythropoiesis triggers severe pathophysiological manife

277 However, both human and mouse stress erythropoiesis use signals and progenitor cells that are

278 s RBC production, we comprehensively studied erythropoiesis using knockout mice and hematopoietic pro

279 ocytic anemia and activation of compensatory erythropoiesis via the regulators erythropoietin and ery

280 The regulatory role of mTOR during erythropoiesis was confirmed in vitro by demonstrating a

281 Erythropoiesis was increased in the bone marrow and sple

282 this pivotal work, the role of the kidney in erythropoiesis was shown by Leon Jacobson in 1957 and er

283 Splenic stress erythropoiesis was stimulated in iron-deficient mice rel

284 ndent signaling is a key component of stress erythropoiesis, we found that inflammation also induced

285 eracting hepcidin-driven iron limitation for erythropoiesis, we found that the combination of KY1070

286 To selectively investigate primitive erythropoiesis, we have engineered a new transgenic embr

287 n of Gdf11 has been implicated in regulating erythropoiesis, we hypothesized that genetic disruption

288 iron in mediating testosterone's effects on erythropoiesis, we induced iron deficiency in mice by fe

289 the mechanism by which lenalidomide promotes erythropoiesis, we investigated its action on erythropoi

290 Fs and co-factors during the course of human erythropoiesis, we provide a dynamic and quantitative sc

291 Because autophagy is also important in erythropoiesis, we studied in vitro CD34(+)-derived eryt

292 To identify new regulators of erythropoiesis, we utilize a functional genomic screen f

293 roleukemia cells, knockdown of LPA2 enhanced erythropoiesis, whereas knockdown of LPA3 inhibited RBC

294 glycero-3-phosphothionate (2S-OMPT) promoted erythropoiesis, whereas the LPA2 agonist dodecyl monopho

295 endothelial, and epithelial), sites of fetal erythropoiesis (which notably included the adrenal gland

296 cute anemia or hypoxic stress induces stress erythropoiesis, which generates a wave of new erythrocyt

297 ors may mimic systemic hypoxia and stimulate erythropoiesis, which improves organ oxygen delivery.

298 oinflammatory cytokines inhibit steady-state erythropoiesis, which leads to the development of anemia

299 Anemic stress induces stress erythropoiesis, which rapidly generates new erythrocytes

300 ionally, mtClpX depletion impairs vertebrate erythropoiesis, which requires massive upregulation of h