コーパス検索結果 (1語後でソート)
通し番号をクリックするとPubMedの該当ページを表示します
1 ceptor-destroying sialate-O-acetylesterase ("esterase").
2 on the oligomeric assembly of hemagglutinin-esterase.
3 with no significant change in acetylcholine esterase.
4 ied cells that express a substrate-selective esterase.
5 r hydrolysis reactions catalyzed by a serine esterase.
6 minal domain of calmodulin into an efficient esterase.
7 2 is not a potent inhibitor of acetylcholine esterase.
8 tion affecting the catalytic activity of the esterase.
9 0 cellulase-xylanase and a GH11-CE4 xylanase-esterase.
10 ases, pseudocholine esterase and cholesterol esterase.
11 rough binding the ColQ tail of acetylcholine esterase.
12 of any previously reported de novo designed esterases.
13 as well as controlled deactivation by plasma esterases.
14 esidue peptides that act as Zn(2+)-dependent esterases.
15 of additional not yet characterized lipases/esterases.
16 ggests that o(LA)(8) is a good substrate for esterases.
17 kbiting reaction in vitro, without requiring esterases.
18 o-methacrylates (mono-MAs), are prepared via esterases.
19 for the differences in activities in the two esterases.
20 structure of AF-Est2 with the human carboxyl esterase 1, which has CoA thioesterase activity, reveals
21 main with the typical fold of a carbohydrate esterase 4 and an N-terminal domain unique for this fami
25 he mutant strain lost most of its lipase and esterase activities and displayed reduced virulence in c
26 In S. invicta, male alates had the highest esterase activities followed by workers then female alat
31 ered significantly in monooxygenase and beta-esterase activities, but not in Vgsc gene mutation frequ
35 esidues are positively correlated with fecal esterase activity and acetate level of human diabetes.
36 a significant reduction (p < 0.05) in mantle esterase activity and MgNACR transcript abundance (p < 0
41 binding or provide the protease, lipase, or esterase activity required for entry of the virus into a
45 ver, one strong band (EST = S1; Rm: 27.4) of esterase activity was detected when using homogenates of
47 able microorganisms exhibiting intracellular esterase activity were detected on >90% of both NC types
48 s seem to exhibit no significant protease or esterase activity when tested against analogous substrat
49 Optimized conjugate 16 was designed so that esterase activity will liberate 5 and cathepsin K cleava
52 are bifunctional enzymes containing a trans-esterase activity, which is responsible for nicking the
53 se/esterases and we demonstrated that it has esterase activity, with preference for short-chain fatty
64 ere are many fully characterized acetylxylan esterases (AcXEs); however, the enzymes deacetylating ma
69 , temperature and substrate conditions using esterase and caseinolytic activity assays and time cours
73 characterized a novel periplasmic trilactone esterase and suggested a new model of FeEnt acquisition
74 er hydrolysis reaction catalyzed by a serine esterase and, therefore, one no longer can simply assume
76 Nature for activating modern enzymes such as esterases and dehydratases and also for proteins like op
77 ain removal from the different plasticizers (esterases and enzymes involved in the beta-oxidation pat
78 binding pockets of coronavirus hemagglutinin esterases and influenza virus C/D hemagglutinin-esterase
80 res similarities with other bacterial lipase/esterases and we demonstrated that it has esterase activ
82 e ester group and thus its susceptibility to esterase, and structural features critical to the lacton
83 ion and activity of the enzyme pectin methyl-esterase, and the chelation of calcium by pectic acids.
85 EGG pathway profiling predicts that kinases, esterases, and hydrolases may contribute to venom activi
87 gests that MHETase evolved from ferulic acid esterases, and two homologous enzymes are shown to exhib
91 was significantly elevated expression of an esterase, arylacetamide deacetylase (AADAC), in vascular
92 ibition of pancreatic lipase and cholesterol esterase, as well as cholesterol micelle formation and b
93 ses, polysaccharide lyases, and carbohydrate esterases, as well as accessory, redox-active enzymes fo
95 n be restored by the action of porcine liver esterase both in vitro and on the surface of living cell
96 lysis but is a highly reactive substrate for esterases both in vitro and in cellulo, yielding a brigh
97 or their capacities to inhibit acetylcholine esterase but, in contrast to the predictions from dockin
98 The sulfocoumarins were hydrolyzed by the esterase CA activity to 2-hydroxyphenyl-vinylsulfonic ac
99 Unlike coumarins which are hydrolyzed by the esterase CA activity to the corresponding 2-hydroxy-cinn
100 knockdown approach, we identified a specific esterase, carboxylesterase 1, whose function had a clear
102 on until entry into a cell, where endogenous esterases catalyze the hydrolysis of the masking groups,
103 tified a mutant G4C/S10C/T172R/G173Q cocaine esterase (CCRQ CocE) with an in vitro duration of action
104 contains a C-terminal family 4 carbohydrate esterase (CE4) catalytic domain, but unlike other MurNAc
105 arrel common to the family four carbohydrate esterases (CE4s) with the canonical motifs circularly pe
108 ssay for total cholesterol using cholesterol esterase/cholesterol oxidase coupled with the luminol-H2
110 ICS1-AM, designed to permeate cells, undergo esterase cleavage, and allow intracellular calcium level
112 ave previously identified caffeoyl shikimate esterase (CSE) as an enzyme in the monolignol biosynthes
114 -5-hydroxylase (F5H), and caffeoyl shikimate esterase (CSE), were targeted by MYB31 or MYB42, but in
118 three amino acids within a highly conserved esterase domain in putative PMR5 orthologs are necessary
119 inds to a conserved epitope in the vestigial esterase domain of hemagglutinin (HA) and blocks HA-medi
122 y modest architectural changes in lectin and esterase domains; and (iii) a single, inconspicuous Ala-
123 articles are fully degradable in response to esterases due to an embedded ester cross-linker in the p
124 due to the activity of beta-glucosidase and esterase during the first months of storage and then a s
125 apid hydrolysis, catalyzed by intrabacterial esterases (e.g., BioH and YjfP), to generate chloramphen
131 of glutathione-S-transferase (GST), general esterases (ESTs) and phenol oxidase (PO) decreased in th
132 All of the new VoltageFluors targeted by esterase expression (VF-EXs) report single spikes in cul
133 ses (EC 3.1.1.73), belonging to carbohydrate esterase family 1 (CE1), hydrolyze ester bonds between f
139 sterase domains in BiFae1B with the feruloyl esterase from Clostridium thermocellum suggest that both
140 inetic parameters for catalysis by pig liver esterase from either initial rates or the integration of
145 of eight aliphatic polyesters by two fungal esterases (FsC and Rhizopus oryzae lipase) at different
147 ed amino acid substitutions in hemagglutinin-esterase fusion (HEF) glycoproteins suggests that antige
150 sites of 43 active SHs encompassing lipases/esterases, GDSL lipases, proteases, Ser carboxypeptidase
152 hat the recently characterized acetylcholine esterase gene, choE (PA4921), is also regulated by GbdR.
153 n(2+) bimetallo core is an effective mono/di-esterase generalist and that the bimetallo cores were no
155 even PYP/XES (Pale Yellow Petal/ Xanthophyll esterase) genes were identified in Citrus genomes, but o
158 tudy provides evidence that purified O. oeni esterases have the ability to both synthesise and hydrol
159 ycans via spike protein S with hemagglutinin-esterase (HE) acting as a receptor-destroying enzyme.
160 outbreaks have shown that the hemagglutinin-esterase (HE) genes of the viruses fall into two of the
163 complex of the ISAV F and ISAV hemagglutinin esterase (HE) proteins in an unknown stoichiometry prior
167 fferences were observed and strains with low esterase hydrolysis activity against artificial substrat
168 QALs, FQALs) selectively, while chlorogenate esterase hydrolyzed all chlorogenic acids (CQAs, FQAs) a
172 t drug 1 in vivo by alkaline phosphatase and esterase in a stepwise manner, providing higher exposure
176 sterase is more effective than pseudocholine esterase in maintaining sequential degradation until >90
178 usceptible to enzymatic hydrolysis by plasma esterases in a controllable manner, while their metaboli
182 ts received intravenous recombinant human C1 esterase inhibitor (50 IU/kg; maximum 4200 IU) twice wee
183 cks of hereditary angioedema (HAE) due to C1 esterase inhibitor (C1-INH) deficiency (C1-INH-HAE) incl
186 we demonstrate that secreted protease of C1 esterase inhibitor (StcE), a bacterial protease from Esc
190 assess the efficacy of recombinant human C1 esterase inhibitor for prophylaxis of hereditary angio-o
195 4200 IU) twice weekly, recombinant human C1 esterase inhibitor once weekly and placebo once weekly,
196 ATION: Prophylaxis with recombinant human C1 esterase inhibitor provided clinically relevant reductio
197 n hIL1ra(Ast)(+/+) mice, the cholinergic ACh esterase inhibitor pyridostigmine increases ACh levels a
198 XII-driven coagulation and the ability of C1-esterase inhibitor to bind and inhibit activated FXII we
199 assays using the P450 inhibitor PBO, or the esterase inhibitor TPP resulted in markedly increased mo
200 nificantly reduced with recombinant human C1 esterase inhibitor twice weekly (2.7 attacks [SD 2.4]) a
201 ents given twice-weekly recombinant human C1 esterase inhibitor, 13 (45%) of 29 patients given the on
202 y plasmin, escape from inhibition through C1 esterase inhibitor, and elicit excessive bradykinin form
203 lated to treatment with recombinant human C1 esterase inhibitor, but both resolved without additional
204 rmacokinetic profile of recombinant human C1 esterase inhibitor, our results suggest that efficacy of
208 unctional proteome analysis using lipase and esterase inhibitors revealed a subset of candidate genes
209 bled eight copies of a C3-symmetric trimeric esterase into a well-defined octahedral protein cage by
210 shown that high expression of a non-specific esterase is critical for the low overall ester content o
212 falciparum Prodrug Activation and Resistance Esterase) is required for activation of esterified pepst
213 io-3-oxobutyl groups have been introduced as esterase-labile phosphodiester protecting groups that ad
214 determination of infection enzyme leukocyte esterase (LE) in human synovial (joint) fluid and urine.
215 ized and tested as a substrate for leukocyte esterase (LE), an enzyme produced by leukocytes (white b
216 the Xf secretome revealed a putative lipase/esterase (LesA) that was abundantly secreted in bacteria
217 mal UA finding (greater-than-trace leukocyte esterase level, positive nitrite test result, or pyuria)
219 pv oryzae (a bacterial pathogen) or lipaseA/esterase (LipA; a cell wall-degrading enzyme of X. oryza
222 e slr2103, with sequence similarity to plant esterase/lipase/thioesterase (ELT) proteins, is essentia
223 ty of catalytic tandem reactions that employ esterases, lipases or alcohol dehydrogenases and gold(I)
224 Prodrugs that release hydrogen sulfide upon esterase-mediated cleavage of an ester group followed by
225 Importantly, we also demonstrate that the esterase-mediated rapid lysis of M. tuberculosis signifi
226 crystal structure of the metal-ion dependent esterase MGS0169 from the amidohydrolase superfamily rev
228 lity = 85%, chi(2) = 134.04, p < 0.0001) and esterases (mortality = 56%, chi(2) = 47.31, p < 0.0001).
231 g protein 6, also known as neuropathy target esterase (NTE), which is the target of toxic organophosp
232 that LipC is a novel cell surface-associated esterase of M. tuberculosis that is highly immunogenic a
235 ophytic fungus Eupenicillium shearii FREI-39 esterase on halloysite, using graphite powder, multi-wal
236 ding reactivity, inhibition of acetylcholine esterase or uncoupling of oxidative phosphorylation.
237 on level of specific enzymes like proteases, esterases or glycosidases is often higher in tumor cells
238 DA-ZP1-TPP is insensitive to intracellular esterases over a 2-h period and is impervious to proton-
239 gene expression in the cancer cells high in esterases over fibroblasts low in esterase activity.
240 t in TraB proteins, but also in erythromycin esterase (Pfam ID: PF05139), DUF399 (domain of unknown f
241 nt parasite mutants, we find that a parasite esterase, PfPARE (P. falciparum Prodrug Activation and R
242 with the surface glycoprotein hemagglutinin esterase phylogeny, were observed between the two lineag
245 an be removed by the action of porcine liver esterase (PLE) to reveal the bright unmodified VoltageFl
246 esterification via decreasing pectin methyl esterase (PME) activity in roots and leaves under unstre
247 The inactivation kinetics of pectin methyl esterase (PME) during the shelf life (4 degrees C-180 da
248 ntially demethyl esterified by pectin methyl esterase (PME) to strengthen or loosen plant cell walls
249 ppressed by a null allele of a pectin methyl esterase (PME3) whose activity normally leads to cross-l
250 gues seem the sole pimeloyl-ACP methyl ester esterase present in the Helicobacter species and their o
252 The heterologous overexpression of this esterase proved a remarkable ability to hydrolyse both n
253 r kinetic studies of 2-step enzymolysis by 2 esterases, pseudocholine esterase and cholesterol estera
256 hydrophilic polyethylene glycol (PEG) and an esterase-responsive hydrophobic dendron, to prepare and
262 eal a conserved epitope in the HA1 vestigial esterase subdomain that is some distance from the recept
264 core of the transition in lectin ligand and esterase substrate specificity; (ii) in consequence, the
268 es were evaluated with nitrite and leukocyte esterase tests, using urine culture and/or dipslide with
269 ble antimalarial; (2) PfPARE is a functional esterase that is capable of activating prodrugs; (3) Mut
270 work has shown that Oenococcus oeni produces esterases that are capable of hydrolysing artificial sub
272 ely, most microorganisms encode carbohydrate esterases that strip readily accessible methyl and acety
273 ilarity to a class of proteins that includes esterases, the heme-binding protein ChaN, and an unchara
274 ast to previously described chlorogenic acid esterases, the reUmChlE was also active towards feruloyl
277 he persulfide prodrug can be activated by an esterase to generate a "hydroxymethyl persulfide" interm
278 ctin (NP) was de-esterified by pectin methyl esterase to produce modified pectins [MP (42, 37, and 33
279 f taurine and D-peptide allows intracellular esterase to trigger intracellular self-assembly of the D
282 rability and efficacy of a novel cholesterol esterase transfer protein (CETP) inhibitor TA-8995 in pa
285 ible hollow cage comprising 20 copies of the esterase trimer, 60 protein subunits in total, with over
288 rgistic combination of xylanase and feruloyl esterase was found to be the most efficient enzymatic tr
289 tyl Neu5Ac by lentiviral transduction of the esterase was lethal to ALL cells in vitro even in the pr
292 ALE: Phosphodiesterase 2 is a dual substrate esterase, which has the unique property to be stimulated
293 Phosphodiesterase 2 is a dual substrate esterase, which has the unique property to be stimulated
294 side hydrolases, sulfatases and carbohydrate esterases, which are primarily located on a 0.89-megabas
296 or CB receptors and is deactivated by plasma esterases while the respective acid metabolite is inacti
298 itive hits, Est WY was identified as a novel esterase with high catalytic efficiency and distinct evo
299 It has been demonstrated to be a serine esterase with sequence similarity to the family CE-3 car