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1 led that VZV ORFs 62, 63, 36, and 14 are all euchromatic.
2 romatic, and in D2, the transgene has become euchromatic.
3 o the more distal regions, which are largely euchromatic.
5 is study describes that condensin reinforces euchromatic A compartments and promotes B-to-A transitio
7 e's "inaccessible" regions: sequences (often euchromatic and containing genes) that are isolated from
8 omatic and gene poor, the mouse MSY is 99.9% euchromatic and contains about 700 protein-coding genes.
10 rosophila results from new juxtapositions of euchromatic and heterochromatic chromosomal regions, and
12 and paired RNAs are strongly correlated with euchromatic and heterochromatic epigenetic histone modif
14 n the cell-cycle-regulated interplay between euchromatic and heterochromatic histone modifications.
15 termination of lncRNA transcription in both euchromatic and heterochromatic lncRNA-based gene silenc
17 family of Drosophila melanogaster, which has euchromatic and heterochromatic members, we find that pr
18 n was supported by its reciprocal effects on euchromatic and heterochromatic PEV; E(var)3-9 mutations
19 eveals structural properties associated with euchromatic and heterochromatic regions in the genome.
20 study changes of chromatin accessibility in euchromatic and heterochromatic regions under extended d
21 llele frequency >0.10 was 95% and 91% in the euchromatic and heterochromatic regions, respectively.
22 ays a distinct spatial segregation of active euchromatic and inactive heterochromatic regions of the
23 ions, including overrepresentation of MSI in euchromatic and intronic regions compared to heterochrom
26 equences that can be mapped to the assembled euchromatic arms, we identified sequences that are speci
30 tion of heterochromatic satellite DNA in the euchromatic brown (bw) gene of Drosophila melanogaster r
31 ls, but not CD177(neg) neutrophils, showed a euchromatic CD177 promoter, unmethylated CpGs, and c-Jun
32 observations suggest that Piwi promotes the euchromatic character of 3R-TAS heterochromatin and its
33 ous component of rice CEN chromatin, and the euchromatic characteristics of rice CEN chromatin are ha
35 eukaryotes, but, interestingly, it can show euchromatic characteristics; for example, the euchromati
36 g a functional role for JIL-1 in maintaining euchromatic chromatin and counteracting heterochromatic
37 osophila phosphorylation of histone H3S10 in euchromatic chromatin regions by the JIL-1 tandem kinase
38 of PEV, suggesting a role for the protein in euchromatic chromatin structure and/or transcription.
40 ysis of eight "wanderer" genes (present in a euchromatic chromosome arm in one species and on the dot
41 xpectedly large fraction of sequences in the euchromatic chromosome arms exhibits a heterochromatic c
42 SMC4/condensin also acts within the mostly euchromatic chromosome arms to suppress conditionally ex
45 t genomes are largely confined to the active euchromatic compartment, consistent with the known funct
47 hat signal-induced nuclear translocation and euchromatic compartmentalization constitute an additiona
49 the locations of FM7 breakpoints to precise euchromatic coordinates and identified the flanking sequ
50 is sufficient to locally silence Arabidopsis euchromatic crossover hot spots and is associated with i
52 histone methyltransferase that catalyzes the euchromatic dimethylation of histone H3 at lysine 9 (H3K
54 datively induced DSBs arise in HC as well as euchromatic DNA and that Artemis and ATM function in the
55 rosophila species, provide information about euchromatic DNA content, they cannot give an accurate es
58 spatially associated with early replicating, euchromatic DNA, which is predominately found in distal
63 romatin structure that functions to maintain euchromatic domains while counteracting heterochromatiza
64 structure and that it functions to maintain euchromatic domains while counteracting heterochromatiza
65 ve sites were identified, some in apparently euchromatic domains, although all are close to heterochr
66 ic properties (e.g., gene density similar to euchromatic domains, replication during polytenization).
68 7me3 occurs in a few (roughly seven) focused euchromatic domains; (5) centromeres and CENP-C are clos
69 Collectively, these XRNs are recruited to a euchromatic DSB and are required for ssDNA production an
70 DSBs are generally repaired more slowly than euchromatic DSBs, and ATM signaling is specifically requ
72 located within transcriptionally permissive euchromatic environments, and promote deposition of hist
74 s, closes 105 and extends into 72 out of 190 euchromatic gaps in the reference genome, adding 1.03 Mb
76 malian reference assembly, yet more than 160 euchromatic gaps remain and aspects of its structural va
77 equence, 363,114 bp of which close 26 of 250 euchromatic gaps, or 10%, including two remaining euchro
83 -marked chromomeres, clearly demarcating the euchromatic gene space; (3) H3K9me2 is restricted to the
84 gene space; (3) H3K9me2 is restricted to the euchromatic gene space; (4) H3K27me3 occurs in a few (ro
85 ased H3K9 methylation accompanied by reduced euchromatic gene transcription and heterochromatin propa
86 transition region structure originates from euchromatic gene-containing segments of DNA that were du
88 ughout all heterochromatic loci and inactive euchromatic genes and is present at the 3' end of modera
89 taneously involved in both the repression of euchromatic genes brought to the vicinity of pericentric
90 topic association of silencing proteins with euchromatic genes important for cell wall integrity and
93 argely conserved between heterochromatic and euchromatic genes, eliminating the hypothesis that adapt
94 elements (MITEs) are closely associated with euchromatic genes, the broader functional impact of thes
95 inary pattern of histone modifications among euchromatic genes, with active genes being hyperacetylat
96 anscriptome analysis, we identified a set of euchromatic genes-enriched in those required for the cel
101 Notably, we found that virtually the entire euchromatic genome (including intergenics) is transcribe
102 enes) that are isolated from the rest of the euchromatic genome by heterochromatin and other repeat-r
104 third chromosome ( approximately 36% of the euchromatic genome) for suppressor mutations of piwi2 an
108 ate that the fraction of the human and mouse euchromatic genomes encoding lincRNAs is more than twofo
110 accessibility to DNase I and an induction of euchromatic H3 and H4 histone acetylations upon nicotina
112 This analysis revealed the pervasive loss of euchromatic H3K9me2 as a conserved feature of pathologic
115 DM4A (dKDM4A), previously characterized as a euchromatic histone H3 K36 demethylase and transcription
117 0638 and UNC0642-two selective inhibitors of euchromatic histone lysine N-methyltransferase-2 (EHMT2,
118 s of histone acetylation, whereas removal of euchromatic histone methylation occurs gradually through
119 y factor 1 (NRF1) regulates transcription of euchromatic histone methyltransferase 1 (EHMT1) to ensur
120 hylation of H3-K9 by the recently identified euchromatic histone methyltransferase SETDB1/ESET may be
122 e H3 dimethylation at lysine 9 (H3K9me2) and euchromatic histone methyltransferases EHMT1 and EHMT2 w
123 eveals that LSD2 forms active complexes with euchromatic histone methyltransferases G9a and NSD3 as w
124 of LMP1 and LMP2A correlated with a loss of euchromatic histone modification H3K9ac and a correspond
125 As shown by chromatin immunoprecipitation, euchromatic histone modification H3K9ac is added at prom
126 uchromatic characteristics; for example, the euchromatic histone modification mark dimethylated H3 Ly
127 ipitation-chip to study the patterns of four euchromatic histone modification marks: H3K4me2, trimeth
129 e 3R-TAS1 piRNA coding sequence restores the euchromatic histone modifications of 3R-TAS and the expr
130 on in the absence of HDA6 activity; instead, euchromatic histone modifications typical of active gene
136 ased H3K9me2/3 in CIITA via up-regulation of euchromatic histone-lysine N-methyltransferase 2 (G9a).
139 ned with the requirement of transcription of euchromatic homologous sequences, suggests a role of dou
141 al analysis is undertaken to verify that the euchromatic human genome is sufficiently complete--conta
144 M1 and the DNA methyltransferase MET1 of the euchromatic, imprinted gene FWA, as its promoter is prov
146 nase in Drosophila localizes specifically to euchromatic interband regions of polytene chromosomes an
147 Early S nuclei exhibited widely distributed euchromatic labeling preferentially localized to regions
148 e S nuclei also exhibited widely distributed euchromatic labeling, but the label was preferentially l
149 te that P-Ser 83-HP1gamma has an exclusively euchromatic localization, interacts with Ku70 (a regulat
152 ibution of SIRT1 to epigenetic regulation at euchromatic loci and whether it acts in concert with oth
155 ngle DSB system for both heterochromatic and euchromatic loci in Drosophila melanogaster Live imaging
156 that tethering Clr4 via DNA-binding sites at euchromatic loci induces heterochromatin assembly, with
157 ncing proteins and discovered 238 unexpected euchromatic loci that exhibited enrichment of all three.
158 lso precludes nucleosome turnover at several euchromatic loci to prevent R-loop formation, ensuring p
159 ilencing complex that is also distributed at euchromatic loci, and with RNA interference component Ar
160 so mediates degradation of antisense RNAs at euchromatic loci, but the underlying mechanism has remai
164 e3 and DNA methylation at a normally active, euchromatic locus but did not bypass the requirement of
167 Strikingly, 90% to 95% of the total genomic euchromatic marks histone H3 acetylated at lysine 9 and
168 er per physical length over the distal first euchromatic megabase pairs of the X chromosome, our data
170 r the recruitment of G9a, the main mammalian euchromatic methyltransferase, and defines nonembryonic
172 localize to a largely non-overlapping set of euchromatic nuclear speckles, suggesting that Set1A and
173 Cerebellar Purkinje neurons have large and euchromatic nuclei, whereas granule cell nuclei are smal
178 n RNAi-dependent H3K9 methylation of several euchromatic pockets, prior to which Argonaute1-associate
180 oding DNA comprises approximately 80% of the euchromatic portion of the Drosophila melanogaster genom
181 ed improvement of the 117-Mb sequence in the euchromatic portion of the genome and 21 Mb in the heter
182 ial and approximately equal fractions of the euchromatic portion of the genome are inferred to contri
185 anscriptional, and chromatin features of the euchromatic portion of the maize genome provide evidence
187 locus is similar to that described in other euchromatic portions of the tomato genome despite the re
189 s with H3K27me3-postive and H3K4me3-positive euchromatic promoters were prematurely induced in hepato
190 e.g., dense packaging, late replication) and euchromatic properties (e.g., gene density similar to eu
192 chromatin structure, and the high levels of euchromatic rDNA induced by the BBDS mutations direct nu
194 es indicated that in juvenile-stage rice the euchromatic region is more actively transcribed than is
195 a 200 copy transgene array integrated into a euchromatic region of chromosome 1 in human U2OS cells.
199 itical in obtaining complete sequence of the euchromatic region of the horse Y chromosome, with an ai
201 molecular markers and a linkage map for the euchromatic region of the Syrian hamster X chromosome th
203 ed heterozygous deletions tiling ~70% of the euchromatic regions and examined their influence on this
204 r Complex), punctate nuclear localisation in euchromatic regions and overlap with Polycomb Group tran
205 e of methylation on meiotic recombination in euchromatic regions and suggests that additional factors
206 hila endocycle, heterochromatin and specific euchromatic regions are underreplicated and reduced in c
207 ng high levels of homolog pairing at all six euchromatic regions assayed and variably lower levels in
208 JIL-1 kinase activity functions to maintain euchromatic regions by antagonizing Su(var)3-9-mediated
209 erochromatin from spreading into neighboring euchromatic regions by recruiting transcription factor T
210 enabled localization of heterochromatic and euchromatic regions for each chromosome of both species.
211 ricentromeres and transformed large formerly euchromatic regions into repeat-rich pericentromeric reg
212 repeat sequences, yet with 30% more compact euchromatic regions it is the smallest known grass genom
213 ses correct in reconstructing megabase-scale euchromatic regions of an eutherian ancestral genome fro
214 - and trimethylation of histone 3 (H3) K9 in euchromatic regions of chromosomes, inhibiting gene tran
215 ions and target genes in heterochromatin and euchromatic regions of reduced recombination, as well as
217 es "ectopic heterochromatin" at sites within euchromatic regions of the Drosophila melanogaster genom
218 ARP-1-dependent Sox2-binding sites reside in euchromatic regions of the genome with relatively high n
219 mediated effects occurring throughout active euchromatic regions of the genome, with very little know
224 we show that MLL5 is recruited to gene-rich euchromatic regions via the interaction of its plant hom
225 tic recombination between markers located in euchromatic regions was significantly higher in both het
226 ciated significantly more often than average euchromatic regions with heterochromatic chromocenters (
227 hese proteins were also enriched in the same euchromatic regions with the high Sir protein levels.
229 including those typically found in gene-rich euchromatic regions, lose DNA methylation in a mutant la
230 n ectopic spreading of H3K9me2 into adjacent euchromatic regions, mimicking the phenotype observed in
231 as methylated in low-turnover nucleosomes in euchromatic regions, notably in the coding regions of lo
238 repeat (180-bp knob sequence) or an abundant euchromatic retroelement (Opie) are undetectable within
239 k1, a core subunit of the CLRC complex, to a euchromatic RNA mediates RNAi-dependent silencing that p
240 gamma-H2AX, by comparing HR occurring at the euchromatic ROSA26 locus between mouse embryonic stem ce
245 es; these findings are in marked contrast to euchromatic segments in these species that exhibit only
248 e nucleotide polymorphism in the most distal euchromatic sequence are approximately one order of magn
249 ed telomeric deficiencies cause deletions of euchromatic sequence followed by subsequent "healing" by
253 we report 2,488,842 bp of previously unknown euchromatic sequence, 363,114 bp of which close 26 of 25
254 aster genome, with the most recent update of euchromatic sequence, gives the first genome-wide view o
255 on base pairs of the human genome's unplaced euchromatic sequence, including more than a dozen protei
258 rmed by this localization of genes and other euchromatic sequences that are embedded within highly re
259 evels of trimethyl H3K9 or the repression of euchromatic sequences were not affected by SET3 downregu
262 ect largely completed the detailing of human euchromatic sequences; however, the most highly repetiti
264 describe a mechanism for spatial encoding of euchromatic signals that repel heterochromatin invasion.
265 ng that this histone variant is required for euchromatic silencing and heterochromatin formation.
266 ut angiosperms in gene body DNA methylation, euchromatic silencing of transposons and repeats, as wel
269 observed broadly distributed throughout all euchromatic sites analyzed, with selective depletion in
270 -4 methylation prevents Sir3p association at euchromatic sites and therefore concentrates Sir3p at un
272 ea mays (maize) minichromosomes derived from euchromatic sites with high-density gene distributions b
273 Sir3 also bound to a surprising number of euchromatic sites, largely at genes expressed at high le
274 ing with Taz1 and the RNAi machinery, and to euchromatic sites, via mechanism(s) distinct from its he
278 noprecipitation (ChIP) assays to analyze the euchromatic state of ORFs 62 and 63 compared to the cent
281 We resolve the complete sequence of 26,079 euchromatic structural variants at the base-pair level,
285 demonstrates that the epigenetic effects of euchromatic TEs, and host genetic factors modulating suc
286 Greater microcolinearity in recombinogenic (euchromatic) than nonrecombinogenic (heterochromatic) re
288 ls or genomic regions that switched from the euchromatic to the heterochromatic compartment during ne
289 n regulating heterochromatin propagation and euchromatic transcription and also suggest that misregul
290 ctive, contain modifications associated with euchromatic transcription, and couple RNAi-mediated tran
294 Still mysterious though is how Piwi targets euchromatic transposons for silencing, but not the speci
295 piRNA loci interact with potentially active, euchromatic transposons to form an adaptive system for t
296 hich support roles for H3K27me2 in silencing euchromatic transposons to maintain genome stability and
297 TA family) in euchromatin, which may silence euchromatic transposons to maintain genome stability dur
299 aldehyde-3-phosphate dehydrogenase promoter (euchromatic), we show that the promoters of ORFs 62 and
300 ction of pachytene chromosome length that is euchromatic, we estimate that approximately 1500 Mbp of