ライフサイエンスコーパス: eventually

1 ng, migration, and immune response pathways, eventually.

2 state cancer (PCa), but all patients relapse eventually.

3 ies and preclinical drug screenings that may eventually accelerate the drug development process for G

4 esicles for axonal sorting and transport and eventually accelerates the proteasomal degradation of KI

5 tes who were offered a DCD50 kidney that was eventually accepted for transplantation.

6 new tools and strategies may be required to eventually achieve malaria elimination in stable transmi

7 nditions, the functionalized Janus particles eventually achieved a limit of detection of 1 pg/mL.

8 cluding those with robust initial responses, eventually acquire resistance to targeted therapies and

9 load on the ubiquitin-proteasome system and eventually activate the intrinsic apoptotic pathway.

10 catenin, C2 renders the target inactive that eventually activates proteasome system for its removal.

11 ns that convert fatty acids to aldehydes and eventually alkanes would provide a means to produce biof

12 hensive sequence-function paradigm that will eventually allow prediction of selective interactions an

13 g engineered reproductive tissues that might eventually allow the restoration of reproductive capacit

14 se channels are currently emerging that will eventually allow us to delineate the molecular determina

15 This ANN model eventually allowed rapid prediction of particle sizes pr

16 iently redirected from fibril formation, and eventually almost all Abeta monomers are integrated into

17 es" in the macaque cortex, processing faces, eventually also extracting information on the other's ga

18 latelets that circulate for several days and eventually are cleared by the liver.

19 at modulating this Th17/Treg imbalance could eventually arrest the RANKL-mediated alveolar bone loss.

20 as delayed rod-mediated dark adaptation and eventually as rod-mediated visual dysfunction in general

21 Eventually, as a proof of concept, the designed biosenso

22 ere is little follow-up data on whether they eventually attain competence.

23 ic state appears at temperatures above 90 K, eventually attaining a volume fraction of 80% around 170

24 -dependent local lung angioedema via B1R and eventually B2R is an important feature of COVID-19.

25 Surface viscous stresses eventually balance the driving capillary pressure in the

26 targeting of VAT-localized Treg cells could eventually be a strategy for improving metabolic disease

27 e main risk factor for such episodes and may eventually be considered as a T2 surrogate marker.

28 This synthetic lethality may eventually be exploited to improve outcomes for patients

29 uncultivated Archaea and Bacteria that could eventually be merged with the ICNP in the future.

30 trade-off between hardness and toughness may eventually be surmounted.

31 and identifies correlative networks that may eventually be targeted in a personalized approach of chr

32 utes to pancreatic cancer invasion and could eventually be targeted in therapy.

33 mprove on existing classifications and could eventually be translated into clinical practice.

34 ing 3D functional cardiac tissues, which can eventually be used for cardiac tissue replacement.

35 in research settings, these approaches might eventually be used in the clinic.

36 This technology may eventually be used to provide real-time guidance and min

37 a quantitative method will allow MS alone to eventually become an indispensable quantitative tool for

38 ith an impaired global coronary reserve, may eventually become irreversible and result in ischemic ca

39 ds were presented in a continuous series and eventually began to repeat.

40 osphamide may cause hemorrhagic cystitis and eventually bladder urothelial cancer.

41 ids and serves as the first layer that would eventually block all homoeologous chromosome pairing in

42 stratocumulus clouds gradually thin and may eventually break up into scattered cumulus clouds, at co

43 ess prevents the early synaptic changes that eventually build up to hyperexcitability in the amygdala

44 ly permeable, lose structural integrity, and eventually burst, releasing their contents into the extr

45 rrangement, loss of genetic information, and eventually cancer.

46 edistribution result in systemic congestion, eventually causing organ dysfunction due to hypoperfusio

47 sulting in attenuated cancer cell growth and eventually cell death.

48 (2) ) leading to chloroplast degradation and eventually cell death.

49 ltering the number of repeating units, which eventually changes sorption selectivity.

50 and methodical ring annulation in deep space eventually changing our perception about the chemistry o

51 ia that can lead to progressive fibrosis and eventually cirrhosis of the liver.

52 s cDC1 induced short-lived effector CTL that eventually cleared the virus.

53 t inflammatory response limits spread of and eventually clears the pathogen, immunopathology is a maj

54 ex ratios to produce unisex populations that eventually collapse, but the underlying molecular mechan

55 e cardiomyocytes with grafted cardiomyocytes eventually comprising only relatively matured ventricula

56 l immunity following repeated infections and eventually constitute a substantial infectious reservoir

57 continuing surveillance and interventions to eventually contain outbreaks of COVID-19.

58 ith the trajectories of the white matter and eventually contribute to cognitive decline.

59 rd more accurate neoantigen prediction which eventually contribute to personalized cancer immunothera

60 and cell type-specific precision required to eventually converge on what this area does.

61 s of noise and variation yet activity has to eventually converge to a stable, reproducible state (or

62 is a prodromal synucleinopathy, as >80% will eventually convert to overt synucleinopathy.

63 on decreased over time and 15.4% of patients eventually crossed over to surgery.

64 hnic and pulmonary complications), which can eventually culminate in clinical conditions ranging from

65 ptic signaling mechanisms during stress that eventually culminate in its delayed impact on the amygda

66 herapies can be used to prevent, manage, and eventually cure IBD.

67 osynthesis, degradation of chloroplasts, and eventually death.

68 imilar developmental and genetic mechanisms, eventually decoupled during the evolution of mammals, al

69 o exhibit severe susceptibility to light and eventually degenerate.

70 uctural and compositional reorganisation and eventually degradation.

71 ANSPCs transiently promotes neurogenesis but eventually depletes it.

72 for a systematic approach to understand and eventually design frameworks with exceptional radiation

73 lung host cells and proliferate inside them, eventually destroying the host cell and releasing numero

74 ntestine, although infectious progenies were eventually detected in large intestine, indicating a cri

75 Nevertheless, Ce-NPs were eventually detected in some seawater samples with low le

76 an to improve current influenza vaccines and eventually develop a "universal" influenza vaccine.

77 the small percentage of individuals who will eventually develop active disease, complicate the estima

78 However, most patients eventually develop Enz resistance that may involve induc

79 However, injured H2-K1 cells eventually develop impaired self-renewal with features o

80 men diagnosed with epithelial ovarian cancer eventually develop recurrence, which rapidly evolves int

81 y in several cancers; however, most patients eventually develop resistance.

82 ants may first present features of STGD1 but eventually develop rod dysfunction, and specific missens

83 ected individuals in the population who will eventually develop the disease, mainly in endemic countr

84 Only two patients eventually developed apraxia of speech, while parkinsoni

85 in understanding the mechanisms of life and eventually developing efficient therapies to treat and c

86 pace with time; that is all proposed metrics eventually deviate from their development trajectory aft

87 ing before age 15 years and do not stop will eventually die of complications from their habit.

88 sting fragments of live cells until the cell eventually dies, a process termed amebic trogocytosis.

89 o a mesenchymal-to-epithelial transition and eventually differentiate into the various tubular segmen

90 rred in 60.6% of pooled patients; 46.2% were eventually discharged.

91 antitumor immune responses of their host and eventually disseminate into distant organs.

92 cative of micellar/emulsion structures which eventually dissociated into choline and geranic acid mol

93 rt cell cycle time had a high probability of eventually dominating the population, due to the heritab

94 The diffused water eventually dries, altering the geometrical parameters an

95 he bistability region of the phase space and eventually drives the switch from bistability to monosta

96 tes, export proteins into the host cell, and eventually egress.

97 Eventually, eight peptides coming from three major hazel

98 mpatibility with the human immune system may eventually enable safe and effective porcine xenotranspl

99 otes Ir ex-solution at the oxide surface and eventually enables the formation of Ir particles (<3 nm)

100 n, how they spread, and how they decline and eventually end.

101 Considerable quantities of PM(1) eventually enter the oceans as suspended particulates, y

102 onal dormancy at early stages, malignant PCs eventually evade immune elimination, leading to progress

103 stem(1), most of which orbit stars that will eventually evolve into red giants and then into white dw

104 pprovals prior to 2016, mostly of drugs that eventually exhibited poor performance in the market.

105 as transit-amplifying intermediate NPs that eventually exit and produce multicellular clones as they

106 About 12% of the eroded organic carbon is eventually exported to inland waters, which is equal to

107 ately predicting cancer evolution, which may eventually facilitate early diagnosis of cancer and dise

108 All hip replacements would eventually fail if in situ long enough and it is importa

109 te high initial efficacy, targeted therapies eventually fail in advanced cancers, as tumors develop r

110 educed N, but in the latter the relationship eventually fails when they reach adulthood with extremel

111 izations of the past and how they emerge and eventually falter is a primary research focus of archaeo

112 Our results may eventually find applications to biosensors, where electr

113 sment of next-generation polio vaccines and, eventually, for other live-attenuated viral vaccines.

114 ro-morphology to absorb and store fluid, and eventually form a self-lubrication film to reduce the re

115 bility that ghrelin-based therapeutics could eventually form the basis of a treatment strategy for il

116 nodentate formate m-HCOO-Fe, before CO(2) is eventually formed via a combination of thermal hydrogen-

117 mula: see text] oligomeric states, yet still eventually forms fibrils.

118 and/or membrane segments migrating there and eventually fusing with the parasite membranes, presumabl

119 arizability of this nonuniform charge system eventually generates the high-energy plasmon.

120 daughter cells that vary widely in size and eventually generating ghost cells.

121 rine processes triggered by traumatic stress eventually give rise to debilitating emotional symptoms,

122 How germ cells develop, function, and eventually give rise to entirely new organisms is an imp

123 fficulty of identifying individuals who will eventually go on to develop a particular disease and by

124 arization, destruction of the cell wall, and eventually growth inhibition of E. coli K-12.

125 hange, continued sea-ice loss is expected to eventually have negative demographic and ecological effe

126 AAs present with more advanced disease and eventually have worse outcomes from COVID-19 infection.

127 leads to reduced myocardial performance, and eventually heart failure.

128 )C nuclei via the triple-alpha reaction, and eventually heavier nuclei as the material expands and co

129 P-1 for its interaction with CD63, which may eventually help design a novel approach for targeting TI

130 produce memory deficits-knowledge that could eventually help in the design of improved clinical treat

131 an assessment of hematopoietic stressors may eventually help predict and prevent the development of h

132 SERS-integrated optofluidic technology might eventually help the triaging of TBI patients and assist

133 ein expression levels in mammalian cells and eventually help to optimize recombinant protein expressi

134 d perfusion at physiological pressures might eventually help to overcome the chronic shortage of tran

135 reach the epidermis, colonising the skin and eventually homing within the hair follicles.

136 rodegeneration does not remain confined, but eventually impacts healthy regions of the brain more bro

137 is to guide therapeutic management of AS and eventually implement recently developed pharmacological

138 ) have led to the expectation that they will eventually improve the treatment of many diseases by add

139 atients with data on the outcome of LEE, LEE eventually improved in 94 (57%).

140 disease is based on skin-directed therapies eventually in association with biologic response modifie

141 , PDT, PTT) and antimicrobial treatment, and eventually in biocompatible therapeutic or diagnostic pl

142 y further investigation in large animals and eventually in human patients.

143 centrated from cell-culture supernatant (and eventually in human serum) on magnetic particles modifie

144 ins, resulting in toxic gain-of-function and eventually in neurodegeneration.

145 yet relevant pioneering transformations are eventually included.

146 he inclusion criteria, with 10 studies being eventually included.

147 Some of these elements were eventually incorporated into syncytial feeding sites.

148 Eventually it is demonstrated that the electrophilicity

149 linical trials and surveillance studies, and eventually it will be implemented in clinical labs.

150 Our experimental framework may eventually lead to a fully quantitative view of how cell

151 ssive accumulation of epigenetic errors that eventually lead to aberrant gene regulation, stem cell e

152 y (eg, infectious diseases, addictions), can eventually lead to further advancements in correctional

153 rces in acutely painful conditions but could eventually lead to greater fatigue and stress of the mus

154 terations of the brain parenchyma, which may eventually lead to neurological deficits or cognitive de

155 the annotation of kidney-relevant data, and eventually lead to new definitions of kidney disease in

156 The insights gained from this overview may eventually lead to new therapeutic interventions.

157 Age-related decay can eventually lead to pathology such as cardiovascular and

158 t viral reservoirs within the CNS, which may eventually lead to rebound viremia.

159 s a test bed for cardiac medical devices and eventually lead to therapeutic tissue grafting.

160 retrocorneal fibrous membrane was observed, eventually leading to graft failure.

161 which then recruits the destruction complex, eventually leading to inactivation of beta-catenin degra

162 iven by incremental changes that accumulate, eventually leading to oncogenic transformation.

163 early changes in pancreatic endocrine cells eventually leading to T1D.

164 However, it eventually leads to a castration-resistant disease that

165 can develop a cytokine release syndrome that eventually leads to acute respiratory distress syndrome

166 , which results in myocardial stiffening and eventually leads to heart failure.

167 itiates a devastating cascade of events that eventually leads to neuronal loss.

168 The unrestricted and chronic immune response eventually leads to severe pain, pus discharge, irrevers

169 disease is managed using bisphosphonate, it eventually leads to total hip replacement due to collaps

170 istant prostate cancer (ERPC) develops which eventually leads to widespread metastasis.

171 oming into, being added to urban stocks, and eventually leaving the city.

172 uter segments and photoreceptor death, which eventually led to decline of visual function in older mi

173 This research eventually led to the discovery of the clinical radiotra

174 loop in the tumor perivascular niche, which eventually lessens tumor initiation and progression in v

175 cause cystic fibrosis (CF), an inherited and eventually lethal disease that impairs the function of m

176 their ability to induce liver necrosis and, eventually, liver cancer.

177 ously, completely losing chromosomal DNA and eventually lysing, even without chromosomal replication.

178 overy of acquired immunologic tolerance" and eventually made organ transplantation a reality.

179 table response towards higher glucose range, eventually making the response catabolic or unresponsive

180 to invest in education and careers, but they eventually marry at high rates and have relatively low r

181 YAP signaling eventually may be harnessed to overcome proliferative qu

182 cteria remain nonresponsive to treatment and eventually may become resistant.

183 ordinated activation of the two systems that eventually merge during autophagy.

184 tropical forests, but these effects would be eventually mitigated with long-term warming probably due

185 hose of a strictly silent scavenger receptor eventually modulating CXCR4 signaling to an active and i

186 esistant cancer cells frequently evolve and, eventually, most tumors become resistant to all availabl

187 mortality, as is indeed widely observed, and eventually neutralise carbon gains due to growth stimula

188 lanar enamine intermediate, the alkaloid was eventually obtained as a 1:1 mixture of C6 diastereomers

189 rocedures and parallel transplantations were eventually omitted.

190 from clinical history, biochemical exams and eventually on histological examination from liver biopsy

191 cation, leading to disruptions of mtDNA and, eventually, optic nerve dysfunction.

192 o efficient cooling of chiral molecules and, eventually, optical tweezer arrays of complex polyatomic

193 yet be better understood, characterized, and eventually optimized.

194 ctive sites and sluggish ionic kinetics, and eventually ordinary electrochemical performance.

195 tegy for individual patients, which might be eventually overcome by current intensive efforts in biom

196 uring initial evaluation of 38 patients with eventually pathology-proven AIFR (13:25, Mucor:Aspergill

197 broad applications of topical steroids; and, eventually, pathway-specific biologic therapy.

198 t of the Bipolar Seesaw Mechanism (BSM) that eventually permitted the completion of T-II.

199 turation of clathrin-coated pits (CCPs) that eventually pinch off and internalize as clathrin-coated

200 e formation of protrusions that elongate and eventually pinch off to form separate daughter cells.

201 ion of care to prevent failure to rescue and eventually poor outcome.

202 giving rise to molecular-scale fracture that eventually produces the flash heating effect.

203 nformation through basal ganglia nuclei that eventually project back to the mPFC to complete the loop

204 ing 1,4-diazabutatrienes, never isolated but eventually proposed as reaction intermediates.

205 identifies 1 in 4 therapeutic relationships eventually proven true.

206 then conditionally grooming (low cost), and eventually providing coalitionary support (high cost).

207 interval between pulses improve resolution, eventually providing values that are comparable to or ev

208 ocated deeper into the channel in steps that eventually pull the native portion of the substrate agai

209 ry congestion, capillary stress failure, and eventually pulmonary vascular disease.

210 us ability to express its transcripts and to eventually reactivate.

211 s is protected from antiviral drugs until it eventually reactivates to produce new virions.

212 a non-native hairpin intermediate (H1) that eventually rearranges into the native fold.

213 pment risk, the probability that a drug will eventually receive regulatory approval, has been notorio

214 is able to bend the fiber for some time, it eventually recoils before coming to a stop.

215 er, in almost an invariable fashion, cancers eventually regrow in the presence of the targeted therap

216 roughput drug screening studies, yet animals eventually reject tumors and cannot be raised at 37 degr

217 GBMs eventually relapse after treatment and the average survi

218 te advances in treatment, up to 30% of women eventually relapse and die of metastatic breast cancer.

219 omas harboring BRAF mutations; however, most eventually relapse due to acquired resistance.

220 However, many patients eventually relapse to the original conditioned fear resp

221 responding to FLT3 inhibitors, most patients eventually relapse with drug resistance.

222 ains relatively low, and patients with HNSCC eventually relapse.

223 doubled in recent years, most patients will eventually relapse.

224 ow these materials interact, encapsulate and eventually release bioactive molecules through an erosio

225 Interestingly, [HXT6/7circle] cells are eventually replaced by cells carrying stable chromosomal

226 ion for younger, lower-risk patients who may eventually require coronary artery disease treatment.

227 A high proportion of eyes undergoing EK eventually require glaucoma surgery and experience graft

228 He eventually required treatment with ecluzimab therapy; a

229 Larval cysts in the human brain eventually resolve and either disappear or leave a calci

230 A few eventually restarted cell division and propagated to for

231 These instabilities eventually result in a self-organized system of nematic

232 omplex cellular and molecular processes that eventually result in cognitive decline.

233 patient's lifetime, others may progress and eventually result in substantial visual and ocular distu

234 ve therapy and cell augmentation therapy may eventually result in the development of alternative, nov

235 in the blood brain barrier (BBB), which may eventually result in the pathogenesis of AD.

236 bvious, persistent low levels of the protein eventually resulted in muscle fiber defects, neuromuscul

237 on of an IgG with the RgEs to various levels eventually resulted in up to 3.5-fold increased titers a

238 o nutritional factors and chronic disorders, eventually resulting in a state of predisposition to imm

239 cytosolic in the absence of immune pressure, eventually resulting in macrophage death.

240 stretched and elongated along with the jet, eventually resulting in the formation of nanoscale groov

241 ane helices of integrin alphaIIbbeta3, which eventually results in parallelization of integrin dimer.

242 gly, treatment with CDK4/6 inhibitors, which eventually results in restraining E2F1 activity, restore

243 However long-time exposure to irradiation eventually results in undesirable shape changes, irradia

244 the spatial distribution of transcripts was eventually resumed, showing that the presence of enhance

245 Lungs were eventually retrieved in 31 patients (34.4%) among the 90

246 and neurogenesis seen in Ccn1 knockout mice eventually returned to normal, the expanded NSC pool was

247 prisingly also in pbcp However, both mutants eventually returned to state 1.

248 potential pathways to self-replication and, eventually, ribozymes.

249 growth of calcium rich axonal spheroids that eventually rupture, releasing material to the extracellu

250 urons, are capable of forming spheroids that eventually rupture, releasing their contents to the extr

251 causes the inner membrane (IM) to shrink and eventually rupture; characterization of mlaA*-mediated l

252 AAAs, which eventually ruptured, demonstrated a significantly higher

253 erload stress, leading to RV hypertrophy and eventually RV failure.

254 up by striated and excretory duct cells, and eventually secreted into saliva.

255 proteins results in early embryo defects and eventually seed abortion, and yet a single wild-type all

256 n vitro that could replace animal models and eventually serve as an in vivo therapeutic.

257 thrombus, blockage of cerebral perfusion and eventually stroke lesion.

258 ther a cluster at 5% relative frequency will eventually succeed with ~80% sensitivity, providing up t

259 is subverted in the majority of patients who eventually succumb to progressive disease.

260 duals that survive initial ASF infection but eventually succumb to the disease are key for the long-t

261 s a plasma cell malignancy and most patients eventually succumb to the disease.

262 , the majority of stage IV melanoma patients eventually succumb to the disease.

263 and regained bowel function, but 2 patients eventually succumbed to progressive peritoneal disease.

264 of other radioelements such as polonium, and eventually super-heavy elements.

265 se vaccine uptake, prevent free riding, and, eventually, support the elimination of infectious diseas

266 and probiotics, alone or in combination, and eventually surgery.

267 cks, accelerating global sea-level rise will eventually surpass current sediment accumulation rates,

268 heterogeneous states, including dormancy, to eventually survive at low metabolic cost and revive in f

269 , uses glutamine and fructose 6-phosphate to eventually synthesize uridine diphosphate N-acetylglucos

270 Chronic, low-grade inflammation of VAT, and eventually systemically, is one of the major drivers of

271 rangements of the cofactor configuration and eventually the protein conformation enable bacteriophyto

272 Eventually, the capability of developed microcarriers fo

273 Eventually, the implementation of validated, accurate CR

274 Eventually, the information collected have been handled

275 Eventually, the oscillating sphere breaks rotational sym

276 hat ultimately ended the Roman Republic and, eventually, the Ptolemaic Kingdom, leading to the rise o

277 Eventually, the young adult patients may proceed to an e

278 evident as the lesions began to resolve, and eventually this area was replaced by hyperreflective, ir

279 the pai-electron density of benzene leading eventually to a Jahn-Teller distorted tropyl (C(7)H(7))

280 in the dynamics and organization of lipids, eventually to a membrane phase transition.

281 of the initially formed benzyl radical lead eventually to carbon-carbon cleavage.

282 d in molecular mass growth processes leading eventually to carbonaceous nanostructures in the interst

283 affects patients' quality of life and leads eventually to decrease of productivity.

284 dysplastic lesions to carcinoma in situ and eventually to metastatic disease.

285 es of elementary chemical reactions, leading eventually to organosulfur molecules-among them potentia

286 , a hierarchical system of brain areas leads eventually to the selective encoding of important featur

287 olate to their chemical characteristics and, eventually, to those of the cocoa beans used for its pre

288 n BrainPhys, non-neuronal cells appeared and eventually took over the cultures.

289 Many LGGs eventually transform into a more aggressive or malignant

290 longer time on a CVC, but are more likely to eventually transition to permanent access.

291 While these findings can eventually translate into personalized spray usage instr

292 signaling in airway smooth muscle cells that eventually triggered cAMP/PKA-dependent relaxation of ai

293 ctures that protect the ends of chromosomes, eventually triggering cellular senescence.

294 s 57% in the conservative group (many of who eventually underwent surgery).

295 on to graft-versus-leukemia reactions and to eventually use KIR genotype information for donor select

296 haracteristic mass fragments, which could be eventually used for on-site detection and monitoring all

297 Eventually, we determined that phospholipid reconfigurat

298 Eventually, we identified multiple inputs from various p

299 Seventeen (81%) were eventually weaned off mechanical support successfully, b

300 as "no reason given." Most of the surgeries eventually were performed-to-date (64.2%); the mean +/-