ライフサイエンスコーパス: evidence

1 ity due to comorbid conditions (low-strength evidence).

2 tion with liability risk and 5 found limited evidence.

3 almost two decades despite a lack of direct evidence.

4 viral life cycle, based on several lines of evidence.

5 nce, and 42 articles were rated as level III evidence.

6 cognitive, notably by choice and accumulated evidence.

7 ognitive performance naturally improves when evidence accumulation is constrained upon committing a d

8 postulated, both triggered by HBr, which is evidenced also to take part in the Z/E isomerization of

9 ess, this study presents the first empirical evidence and an important baseline for ingestion of micr

10 degrees to 120 degrees C sediments, isotopic evidence and increased cell concentrations demonstrate t

11 d neurodegeneration framework, the available evidence and potential alternatives on how to establish

12 isease guidelines have been updated with new evidence and provides newer options for diagnosis and tr

13 ed with evidence updates to identify any new evidence and to help determine which topics should be th

14 Three articles were rated as level II evidence, and 42 articles were rated as level III eviden

15 nal, expert-led consensus project to develop evidence- and experience-based guidelines for the manage

16 s for cerebellar mechanism, and we show that evidence appearing to contradict the original model is b

17 We consider the varied experimental evidence arising from the application of X-ray diffracti

18 Here, we provide compelling evidence associating the type of information being proce

19 We also discuss the current evidence base for a cytoreductive strategy, including me

20 e when it is needed, as well as providing an evidence base for efficiently distributing limited healt

21 The evidence base for methods to support nursing staff to de

22 ndate, more research is needed to provide an evidence base for teaching and practice in this area.

23 mendations for the development of a stronger evidence base, with the hope that this paper serves as a

24 we describe research pipelines that broaden evidence-based approaches and the pathobiology of these

25 atically discuss the contemporary role of an evidence-based fibrinolytic reperfusion strategy as part

26 Utilizing an evidence-based framework, 3 gene curation teams blinded

27 Evidence-based guideline development for surgical and de

28 rs to adopt guidelines, the establishment of evidence-based guidelines would be of benefit to the per

29 ons are unexpected based on efficacy data or evidence-based guidelines.

30 knowledge, the first one that provides novel evidence-based information for risk-adapted starting age

31 This evidence-based intervention could be part of EtHE.

32 Evidence-based interventions can deliver substantial pub

33 e for policymakers charged with establishing evidence-based policy to determine whether an RCT with h

34 We aimed to identify evidence-based predictors for outcomes in pediatric UC,

35 inical trial protocol reporting by providing evidence-based recommendations for the minimum set of it

36 calls to replace traditional lecturing with evidence-based, active-learning course designs across th

37 and the articles were rated for strength of evidence by the panel methodologist.

38 nOVAmax induced a regulatory DC phenotype evidenced by a decrease of the activation marker CD86 an

39 e activation of apoptotic cellular events as evidenced by both terminal deoxynucleotidyl transferase

40 markedly reduced MI/R injury in DM mice, as evidenced by improved cardiac function (increased LVEF a

41 ndings support the hypothesis that fibrosis, evidenced by increased elastic modulus, is enhanced in D

42 nophils are capable of metabolic plasticity, evidenced by increased glucose-derived lactate productio

43 ine is critical for normal motor control, as evidenced by its importance in Parkinson Disease and rel

44 the nickel complex at polymer chain ends is evidenced by nuclear magnetic resonance spectroscopy, en

45 energy transfer (around 90% efficiency), as evidenced by time-resolved spectroscopy.

46 Evidence consistent with adaptation includes optimality

47 Study 4 found evidence consistent with this mechanism.

48 behavioral data, there is no neurobiological evidence demonstrating that cannabinoids can also alter

49 Current clinical evidence does not support stopping angiotensin-convertin

50 ion of reactive strategies, little empirical evidence exists as to whether such strategies are approp

51 ous genes or proteins for which experimental evidence exists.

52 ded to each other's work scored the level of evidence for 17 genes reported to cause LQTS.

53 Whilst this study provided some evidence for a 'parity-frailty trade-off', there was lit

54 These findings provide evidence for a mechanism by which PPARalpha attenuates h

55 Here, we provide evidence for a previously unknown quality control mechan

56 PunPgp-9 in Saccharomyces cerevisiae provide evidence for an interaction with ketoconazole and iverme

57 There was no evidence for associations of physical activity with hist

58 This study provides Class IIb evidence for beneficial effects of STN-DBS on NMS at 36-

59 In contrast, for short-stopping we found evidence for both individual plasticity (individuals dec

60 d insertion/deletion mutations, and provided evidence for correction of mis-annotated 28 C-terminal r

61 ed directly by cyclic di-GMP, which provides evidence for cross-regulation between different CDN path

62 Collectively, these data provide compelling evidence for early stage TRM fate decisions and the exis

63 This study provides evidence for FA-mediated regulation of BCAA-catabolizing

64 Collectively, these findings provide genetic evidence for FBP1 as a metabolic tumour suppressor in li

65 The certainty of evidence for glycemic control by subgroup was moderate f

66 These data provide further evidence for heterogeneous selection on Mpi.

67 ss northeast Australia, as well as serologic evidence for HPG in multiple pteropid bat species, while

68 The etiology of isolated BA is unknown, with evidence for infectious, environmental, and genetic risk

69 of the major fatty acids, provides chemical evidence for milk, meat, and plant processing by ancient

70 Although the strength of evidence for most interventions was low or very low, int

71 In summary we provide strong evidence for pathogenicity of this variant in a member o

72 We also found evidence for potential, SIB-specific FC signature, which

73 hus, the current study has not only provided evidence for reconciling a previously identified conflic

74 However, evidence for selective proactive control before stopping

75 Together, our findings provide evidence for selective SARS-CoV-2 neurotropism and suppo

76 beetles, show that trace fossils can provide evidence for short-term (possibly years to decades) chan

77 Here we report the biochemical evidence for the ability of photosystems to form extende

78 loci that are associated with PID, and found evidence for the colocalization of-and interplay between

79 " in the United States and sought additional evidence for the connection to tick bites.

80 roughput sequencing, we provide experimental evidence for the developmental importance of miRNAs in a

81 bridization and immunohistochemistry we find evidence for the expression of opsins and phototransduct

82 This formal genetic evidence for the importance of Btnl heteromers also appl

83 These findings provide novel evidence for the participation of cerebellar structures

84 r 6 to 9 mo following vaccination, providing evidence for the persistence of germinal center activity

85 The definitive evidence for the presence of metaphosphates, reported he

86 We present the current evidence for the two proposed models of EET taxis, "elec

87 epending on the group's order, but empirical evidence for this is lacking.

88 support during heterolytic H(2) adsorption; evidence for this phenomenon was observed during in situ

89 relatively low ribosome abundance, providing evidence for translational tuning to balance protein syn

90 was originally described as a cycad, but new evidence from cuticle structure suggests that it is an a

91 Evidence from full text articles, abstracts, and data pr

92 Recent evidence from human newborns and non-human animals has c

93 When combining multiple pieces of evidence from many different sources, it is important to

94 The corroborative evidence from multiple levels including molecular, brain

95 oimmune encephalomyelitis (EAE), substantial evidence from patients with MS points to a role for CD8+

96 Evidence from postmortem brain studies have indicated th

97 disease, this systematic review analyses the evidence from rigorously evaluated programmes that seek

98 we synthesize experimental and observational evidence from studies of children and adults from divers

99 r persons on the basis of the best available evidence from systematic reviews and individual studies.

100 We address the evidence gap with an economic analysis of the costs and

101 Comparative evidence generation is even sparser for medical devices.

102 Recent evidence has demonstrated that tau oligomers, small and

103 Since then, significant evidence has emerged to support the etiologic role of MC

104 Accumulating evidence has indicated that circRNAs can directly bind p

105 Genetic evidence has revealed that the accumulation of glucosino

106 Here, we discuss recent evidence highlighting the importance of these specialize

107 Based on current evidence, imaging plays an ancillary role in the managem

108 Substantial evidence implicates crosstalk between metabolic tissues

109 Converging evidence implicates redox dysregulation as a pathologica

110 Despite mounting evidence implicating inflammation in cardiovascular dise

111 Evidence in cells and in vivo demonstrates promising res

112 However, recent evidence in human and rodent chronic sleep restriction (

113 However, genetic evidence in mouse models for prostate cancer to support

114 Experimental evidence in rodents and humans suggests that long-term m

115 The present study provides evidence in support of limiting alcohol intake in adhere

116 ds significant weight to the growing body of evidence in the use of plasma p-tau181 as a non-invasive

117 Combining multiple lines of evidence, including radiocarbon dating, body size recons

118 atient and environmental factors, but recent evidence indicates an additional role for the genetic di

119 Background Growing evidence indicates an association between cerebral micro

120 Recent evidence indicates Bcl2 mediates exercise-induced autoph

121 Emerging evidence indicates dynamic functions for various MAPs in

122 Increasing evidence indicates that early neural measures implicated

123 Growing evidence indicates that peripheral neuropathy (PN) is co

124 Accumulating evidence indicates that persistent Helicobacter pylori g

125 Mounting evidence indicates that SUMOylation plays a crucial role

126 Emerging evidence indicates that these disruptions can be related

127 Accumulating evidence indicates weak correlations between self-report

128 In this review, I will highlight new evidence indicating that neonatal T cells are not inert

129 has led the charge to develop and implement evidence-informed interventions toward achieving this go

130 Evidence is accumulating that humans synchronize these n

131 Evidence is emerging that it can also influence psychiat

132 We caution that the evidence is largely preliminary and suggest directions f

133 Evidence is valuable because it informs decisions to pro

134 These data provide evidence linking risk-associated variation to genes that

135 In the context of emerging evidence linking sphingolipid biology with cardiovascula

136 rises to 8.7 if we accept the more disputed evidence of (13)C-depleted zircon deposits.

137 other sensory cortices, our results provide evidence of a common mechanism for cortical computations

138 oss of OL and demyelination, providing clear evidence of a copper-iron connection in CZ-induced neuro

139 he intention-to-treat analysis, there was no evidence of a difference in the proportion of participan

140 17 aggregate scores (p<0.0001), but we found evidence of a high degree of collinearity between the ex

141 ersely, we find no statistically significant evidence of a higher false discovery rate, on average, f

142 Second, we find evidence of a segregation effect, since mobility contrac

143 Recombination between viruses provides evidence of a shared host, in which genetic exchange occ

144 n around the 90-minute cutoff did not reveal evidence of a significant discontinuity (P=0.66).

145 mood comorbidities, these findings serve as evidence of altered neurochemistry in BD youth that is s

146 in nonobstetrical care settings, 15 found no evidence of an association with liability risk and 5 fou

147 For patients with stable CAD, PCI shows no evidence of an effect on any of these outcomes.

148 staining in undamaged DDH cartilage, with no evidence of augmented cell death by activation of caspas

149 h for biosignatures (i.e., the spectroscopic evidence of biological activity) in exoplanets.

150 f thousands of yeast cells and reveals ample evidence of both vertical and horizontal pleiotropy.

151 Evidence of CKD was found in 18,034 (6.4%) participants.

152 raretinal fluid, and/or cystoid spaces); (2) evidence of CNV activity on FFA identified by the presen

153 th FFA and SD OCT data were analyzed for (1) evidence of CNV activity on SD OCT (presence of subretin

154 On the other hand, evidence of communication in the context of coordination

155 s evidence of purifying selection but little evidence of diversifying selection, with substitution ra

156 from Mycobacterium kansasii with and without evidence of donor and acceptor substrate binding obtaine

157 While we provide systematic evidence of environmental impacts from food fraud, our r

158 mice demonstrated phenotypic and biochemical evidence of GH excess including significantly elevated i

159 While we found no evidence of global differences in GI between domestic an

160 pectively, both patients were alive, without evidence of graft-versus-host disease, with major infect

161 ducing bacterial cues and to IL6, and showed evidence of higher TCR-transmitted signals, which are al

162 r quality data, and dye tracer tests provide evidence of human fecal contamination in the private wel

163 , notwithstanding a dearth of archaeological evidence of human predation.

164 There was no evidence of interaction between MRD status and condition

165 There was no evidence of large reductions in SFA, but we are unable t

166 dependent monomer-to-dimer transition, clear evidence of membrane association, and probable structure

167 rculosis (PTB) patients lack microbiological evidence of Mycobacterium tuberculosis, and misdiagnosis

168 patients (79%) were found to show additional evidence of occult retinal vasculitis on FA.

169 n and telemetry studies, our results show no evidence of population structure (non-significant F(ST)

170 There is evidence of purifying selection but little evidence of d

171 We also found evidence of racial/ethnic disparities in PBDE exposures

172 There is anecdotal evidence of reduction in organ donation and transplantat

173 We found substantial evidence of secondary infections among household contact

174 tive to sample weighting, and there was some evidence of small gains in precision when using MRP, par

175 psis was defined by electronic health record evidence of suspected infection and sepsis treatment or

176 Twenty-nine samples from individuals with no evidence of TB infection by TST and no known exposure to

177 trial, and omnivorous animal provides direct evidence of the deep history of directional behavior amo

178 sychiatric diseases and there is post-mortem evidence of their deficit in FTLD.

179 tle research in avian systems, despite ample evidence of their effects in mammalian systems and that

180 In this work we report clear evidence of water stability in a lead-free metal halide

181 The observed SDS-PAGE bands did not show any evidence of zein crosslinking.

182 f a 4-part JACC Focus Seminar, we review the evidence on the complex mechanisms leading to MIF, as we

183 his article synthesizes the available global evidence on the drivers of national declines in stunting

184 However, current evidence on their effects is conflicting.

185 The authors suggest a reevaluation of this evidence or acknowledgement of these deficiencies in the

186 ystematic review of the literature collected evidence regarding nutritional, pharmacologic, and other

187 Current evidence regarding the common pathways for genetic patho

188 ects all aspects of an individual's life but evidence relating to the causal effects on health is lim

189 New evidence reported by Solomon et al. that hippocampal act

190 Both basic and clinical evidence reveal dual roles for GJs, in tumor suppression

191 The evidence reviewed in this work combines the expert clini

192 Resourcing real-world evidence (RWE) is becoming an increasingly important ass

193 For VTE, moderate-certainty evidence showed a probable association with older age; e

194 e median follow-up of 1 year, high-certainty evidence showed that dual therapy was associated with re

195 The target article reviews evidence showing that technological reasoning is crucial

196 quality was dually assessed, and strength of evidence (SOE) was determined by consensus according to

197 linical utility must be derived from level I evidence studies.

198 the consideration of additional experimental evidence (such as information on biotransformation pathw

199 We present evidence suggesting pressure to reduce reflected biolumi

200 However, past evidence suggesting such a gain adjustment rests on subj

201 Published evidence suggests a positive association of self-reporte

202 at this early scorpion was terrestrial, this evidence suggests that ancestral scorpions were likely c

203 Although environment has undeniable impact, evidence suggests that genetic factors play a significan

204 Accumulating evidence suggests that individuals with glucose metaboli

205 Preclinical evidence suggests that iNPWT may also prevent wound dehi

206 Accumulating evidence suggests that lncRNAs have the potential to be

207 nce fluidity of blood, although accumulating evidence suggests that sublethal blood trauma-induced by

208 Evidence suggests that the complex process of senescence

209 Emerging evidence suggests that the contribution of hippocampus t

210 Collectively, the evidence suggests that vascular pathology is a likely pa

211 Recent behavioral evidence suggests that we construct an implicit model of

212 These data add to the growing body of evidence supporting an active role of astrocytes in brai

213 Despite accruing evidence supporting its benefit following pancreatoduode

214 er low-risk patients on the basis of current evidence supporting TAVR valve durability.

215 We have evidence supporting that E4BP4 may suppress the AMPK act

216 Here we provide evidence supporting the key predictions that prestige-bi

217 onal efforts regarding these targets and the evidence supporting their clinical utility in youths.

218 scheme for treatment decisions, the present evidence supports screening for and targeting of modifia

219 ers are potentially reversible, and emerging evidence supports that addressing these modifiable risks

220 In translational research, evidence supports the role of WBP2 as a biomarker for ea

221 Pairing our findings with evidence that (1) C15:0 is not readily made endogenously

222 We present evidence that a clinical trial examining the effects of

223 In this study, we provide evidence that a metabolic shift from glucose to lipid is

224 Here, we report the first evidence that a radical SAM enzyme MoaA accelerates the

225 Overall, these studies provide evidence that a signaling axis involving key UPS compone

226 ing chimeric Fls2/Fls3 proteins, we found no evidence that a single receptor domain is responsible fo

227 Our data add to the growing body of evidence that AAA+ molecular machines generate transloca

228 These results provide evidence that abnormalities in GPHYSD1 patients with thi

229 This study provides evidence that acalabrutinib is active as single-agent th

230 ll widely used; however, there is increasing evidence that bariatric procedures should also be consid

231 In addition to providing evidence that complement function modulates SARS-CoV-2 i

232 There was no evidence that concussion or vision symptom trajectories

233 r data are consistent with a growing body of evidence that cortical networks are particularly vulnera

234 These findings provide strong evidence that cross-modal temporal biases depend on sens

235 r S838A/T841A mutant RB fragment, we present evidence that deficiency for this phosphorylation event

236 This work presents evidence that disturbed flow (DF) induces GCX degradatio

237 ormed the current guidelines, we discuss the evidence that drives individualized HbA(1c) targets, we

238 Here, we provide genetic evidence that Drp1 inhibition is neuroprotective.

239 dy in Nature Medicine contributes to growing evidence that genomic assessment of non-dysplastic BE sa

240 There is extensive evidence that glucocorticoid hormones enhance memory con

241 Therefore, our findings provide evidence that glutamine supplementation can serve as a p

242 e provided genetic, structural, and chemical evidence that Gna1 is an antifungal target in A. fumigat

243 Overall, our study provides evidence that human motor sequence learning occurs outsi

244 This study provides the first evidence that hyperglycaemia may increase influenza seve

245 These results support growing evidence that individual differences in responses to dru

246 There is accumulating evidence that individual variation in foraging behaviour

247 ctivity with the language network, providing evidence that innate connectivity instructs the later re

248 nd devices and assure timely availability of evidence that is useful for decision making.

249 ter et al. in this issue of the JCI provides evidence that KBTBD13 localizes to the sarcomere and can

250 In this study, we demonstrate the first evidence that LASP1 and LASP2 are involved in the format

251 ons: using Mendelian randomization, we found evidence that low expression of IFNAR2, or high expressi

252 We provide evidence that malonyl-CoA, the rate-limiting substrate f

253 Our results provide strong evidence that map expansion alone does not imply improve

254 Overall, the study provides firm evidence that methanol is formed at the interface of Pt

255 Our results provide evidence that most erosion below the Great Unconformity

256 Previous studies provide evidence that non-leaf photosynthesis could be an unexpl

257 Finally, we provide genetic evidence that NPVF acts upstream of serotonin in the RN

258 ng with genetic screening, we provide direct evidence that oncogene-induced loss of progenitor self-r

259 In this Review, we summarize evidence that overactivation of SMAD2/3 signaling pathwa

260 sed towards the beacons, we did not find any evidence that participants successfully exploited the pr

261 e seen in crustacean eyes, providing further evidence that photophores are light sensitive.

262 Finally, we provide evidence that primary FCRL4-bearing human memory B cells

263 urthermore, human studies have provided weak evidence that propensity to discount cost imposed on dru

264 However, there is mounting evidence that resection of the primary tumour and/or loc

265 More generally, they provide additional evidence that RNA virus IBs are important immunomodulato

266 We found little evidence that sex influenced the probability of an indiv

267 The results provide critical evidence that spindles during overnight sleep may act as

268 We found minimal evidence that state-of-the-art machine learning methods

269 This Review weighs the evidence that supports a pathogenic role for PAD enzymes

270 Although we found little evidence that suramin disrupts glycolytic or glycosomal

271 This study provides class A evidence that systematic drug level monitoring of newer

272 There is mounting evidence that systemic uptake of food allergens is key t

273 This study provides quantitative evidence that the airborne fungal ecology of homes with

274 shed mouse model of TB, our new data provide evidence that the alarmin S100A8/A9 mediates neutrophil

275 Thus, to our knowledge, we provide the first evidence that the expression of IL-3R on activated human

276 Here, we present evidence that the miRNA is expressed from an intron that

277 But we await further evidence that the model's substantial complexity informs

278 We provide evidence that the promoter activation rate is influenced

279 or-unbound (free) forms, and we here present evidence that the two pools of Lck have different molecu

280 Finally, we provide evidence that the well-known right lateralization of fac

281 Whereas there is no unambiguous evidence that this early scorpion was terrestrial, this

282 ion of pollen proteins during SI and provide evidence that this modification can affect protein funct

283 etition in general, which is consistent with evidence that upward social comparison reduces political

284 AV vRNA in infected cells and provide direct evidence that vRNA-associated Rab11A have altered transp

285 There was moderate- or high-quality evidence that, compared with placebo, the single-species

286 We provide evidence that, Frizzled/Vang signaling couples to the Fa

287 e this notion is supported by early clinical evidence, the mutation frequencies of these and other fu

288 Despite this evidence, the neural processes that govern cocaine poten

289 Despite the growing body of evidence, the optimal administration regime for ADT has

290 paleo-climatic, archaeological, and genomic evidence to establish the timing of and conditions assoc

291 We provide a narrative review of evidence to guide antibiotic duration in sepsis.

292 ic review used the GRADE approach to compile evidence to inform the European Academy of Allergy and C

293 Here, we present evidence to support a hierarchical process, present in p

294 lopment, and Evaluation) methodology and the Evidence-to-Decision framework, in January 2019, the 13-

295 emaining topics reviewed were addressed with evidence updates to identify any new evidence and to hel

296 This in vitro evidence was corroborated by docking results demonstrati

297 Evidence was graded as convincing, highly suggestive, su

298 n emerging technology with a limited body of evidence, which is of variable methodological quality.

299 This is a qualitative synthesis of new evidence with existing meta-analyses, and studies had se

300 These results provide some of the strongest evidence yet of state-sponsored resettlement in the pre-