ライフサイエンスコーパス: evidence implicating

1 These observations provide the first evidence implicating a Bcl-2 family member in the regula

2 ate disease phenotypes are numerous, yet the evidence implicating a causal relationship of these resp

3 ineffective cytoskeletal reorganization with evidence implicating a downregulation of expression of t

4 dings point to a cancer syndrome and provide evidence implicating a germline mutation in ATR and susc

5 provides the first molecular and functional evidence implicating a GJA1 mutation as a novel pathogen

6 We will discuss evidence implicating a key role for endothelial cells th

7 This study provides evidence implicating a lncRNA in the pathogenesis of ADP

8 le steps of ribosome biogenesis, and provide evidence implicating a mammalian RNA helicase in RNA mod

9 the Spo0 phosphorelay, there is considerable evidence implicating a mechanism of post-translational c

10 ng the past several years, numerous lines of evidence implicating a multistep process of malignant tr

11 asis for this disease has been challenged by evidence implicating a number of divergent etiologic fac

12 Despite mounting genetic evidence implicating a recent origin of modern humans, t

13 Moreover, we provide evidence implicating a requirement for NFkappaB transcri

14 Thus, these results provide genetic evidence implicating a requirement for PKR in mediating

15 There is compelling evidence implicating a role for ACAT1 in macrophage foam

16 The evidence implicating a role for calcineurin signaling in

17 Furthermore, we address the evidence implicating a role for PCP components in ciliog

18 Whereas there is strong evidence implicating a role for phosphorylation of UBF i

19 Here, we provide evidence implicating a role for proline oxidase in renal

20 d its association with AD adds to increasing evidence implicating a role for the innate immune system

21 We describe multiple lines of evidence implicating a trichome-expressed gene from this

22 The evidence implicating a vascular cause in OAG is mounting

23 gether, these observations provide the first evidence implicating abnormal tau in the neurodegenerati

24 These results provide initial evidence implicating abnormal tryptophan/kynurenine path

25 ink is of special interest, because there is evidence implicating actin dynamics in endocytosis.

26 This study provides the first evidence implicating ADAMTS-5 in the regulation of prote

27 This study provides the first evidence implicating aggrecan and aggrecanases in the va

28 d proteomic studies have provided convincing evidence implicating alterations in immune/inflammatory

29 In addition, although we do not find evidence implicating altered proliferation in the rescue

30 The genetic evidence implicating amyloid-beta in the initial stage o

31 ECENT FINDINGS: There is a gathering body of evidence implicating an energy-deficient state in the pa

32 These data also provide the first evidence implicating an important function of Rab26 in c

33 n together, these observations provide novel evidence implicating an important role of autophagy and

34 Our study provides new evidence implicating an important role of THP in influen

35 ovide the first in vivo electrophysiological evidence implicating an L-type calcium channel that modu

36 ur data are consistent with the overwhelming evidence implicating antigen presentation in PD pathophy

37 They review evidence implicating atrial cardiomyopathy as an indepen

38 tively, the data presented provide the first evidence implicating B7-H1 in the suppression of host im

39 provide a biological explanation for recent evidence implicating beclin 1 in human cancer and sugges

40 These results corroborate recent clinical evidence implicating beta-cell dysfunction in the pathop

41 acteria metabolize glycogen is unclear, with evidence implicating both bacterial and human enzymes.

42 Recent evidence implicating both G alpha12 and G alpha13 in the

43 specific endonuclease and are congruent with evidence implicating both hRad52 and XPF/ERCC1 in a numb

44 There is considerable evidence implicating both the glomerular basement membra

45 To review the evidence implicating C pneumoniae in the pathogenesis of

46 These results provide genetic evidence implicating calcineurin as an important mediato

47 This article reviews the evidence implicating calcium and cAMP as central players

48 f cilia in fibrotic growth and summarize the evidence implicating cardiac cilia in heart regeneration

49 These data provide evidence implicating CD4(+) T-cell cytokines in the path

50 Together, the data provide direct evidence implicating CDH23 and PCDH15 proteins in the fo

51 classical and recent advances, including new evidence implicating CENP-A chaperones in this conflict.

52 Evidence implicating CEs in carcinogenesis, in particula

53 Consistent with this, there is increasing evidence implicating chloride in a range of neurological

54 We also review the current body of evidence implicating chromatin modifications and RNA mol

55 There is evidence implicating chromatin remodeling proteins in he

56 Despite strong genetic evidence implicating CLEC16A in autoimmunity, this gene'

57 s central role in biology, with accumulating evidence implicating coding and noncoding (nc)RNAs in my

58 Here we summarise the evidence implicating complement in neurodegeneration, bu

59 Evidence implicating complement in neuroinflammatory and

60 enriched in cancer genomes, but experimental evidence implicating condensin dysfunction in tumorigene

61 Evidence implicating dCK in cancer cell proliferation an

62 These data provide strong genetic evidence implicating de novo synthesis of Ang II in the

63 This article reviews emerging evidence implicating different septins in the regulation

64 In this issue, Duan et al. present evidence implicating DISC1 in the maturation and integra

65 Here, we discuss the evidence implicating disruption of the catecholamines (d

66 Here, we discuss current evidence implicating DNA modifications and DNA-modifying

67 Here we provide evidence implicating DOCK180 in netrin signal transducti

68 In light of the clinical evidence implicating dopamine in schizophrenia and the p

69 In light of evidence implicating dopamine in the pathophysiology of

70 In doing so, we provide direct evidence implicating dopamine in the way tDCS affects co

71 the best of our knowledge, the first direct evidence implicating dopamine in the way tDCS affects co

72 These results provide evidence implicating dorsal striatum in higher-level org

73 There is extensive evidence implicating dysfunctions in stress responses an

74 We also review evidence implicating each of the above MYC genes in spec

75 linical translation and present the emerging evidence implicating ecDNA as an important driver of tum

76 Coupled with recent evidence implicating ecdysone signaling in these embryon

77 eIF2A-knockout (KO) mouse model, we present evidence implicating eIF2A in the biology of aging, meta

78 vivo experiments provided the first genetic evidence implicating elevated levels of these three PRMT

79 In this review, we examine the evidence implicating endoplasmic reticulum dysfunction i

80 There is evidence implicating endoplasmic reticulum stress in the

81 These observations provide cogent evidence implicating endothelial KLFs as essential in vi

82 Evidence implicating energy defects in neurodegenerative

83 We present evidence implicating enhancer priming and the activation

84 Evidence implicating Eph receptor tyrosine kinases and t

85 Epidemiological evidence implicating epigenetic factors includes complex

86 association studies discoveries, and provide evidence implicating epigenetic regulation of reverse ch

87 Herein, the evidence implicating epigenetics in the pathogenesis of

88 before developing an addicted phenotype with evidence implicating estradiol as a potential mechanism.

89 Evidence implicating estrogen as a key breast carcinogen

90 It is also based on evidence implicating excessive NMDA activity in MCS.

91 In addition to providing novel functional evidence implicating FN1 in cardioprotection, these find

92 s preclinical evidence and indirect clinical evidence implicating gamma-aminobutyric acid (GABA) in t

93 s and in rare human diseases, and we examine evidence implicating genetic variations in lipin genes i

94 Our findings, together with previous evidence implicating H2A.Z in transcriptional regulation

95 ene has a key role in epilepsy, but clinical evidence implicating HCN1 mutations in human epilepsy is

96 Our novel evidence implicating helix III differs from evidence tha

97 We now provide evidence implicating hepatic epithelial-derived cytokine

98 ief overview of HIFs; discusses the range of evidence implicating HIFs in beta cell dysfunction, diab

99 ing and memory have provided a great deal of evidence implicating hippocampal mechanisms in the initi

100 Evidence implicating human chromosomes as a site for a g

101 There is increasing evidence implicating human epidermal growth factor recep

102 we examine the origins of gHAT epidemics and evidence implicating human genetics in HAT epidemiology.

103 Together with recent genetic and therapeutic evidence implicating IL-23, these findings suggest a gen

104 These results strengthen the body evidence implicating IL-6 signaling in depression.

105 Despite strong evidence implicating immune dysfunction and genetic pred

106 In this review, we summarize recent evidence implicating important roles for cGAS in the det

107 this perspective, an overview of the recent evidence implicating increased glycolysis and glutaminol

108 This finding generates new evidence implicating increased procoagulant activity and

109 Evidence implicating individual gene polymorphisms (or h

110 Recently, evidence implicating individual genes within some of the

111 The evidence implicating infectious causation suggests that

112 Despite mounting evidence implicating inflammation in cardiovascular dise

113 Because of the evidence implicating inflammation in the pathogenesis of

114 l inflammation and provide the first imaging evidence implicating inflammation in the pathophysiology

115 nging now because there is a growing body of evidence implicating inflammatory cells at every stage o

116 On the basis of considerable evidence implicating inflammatory mediators in the progr

117 We also highlight the genetic and cellular evidence implicating inositol pyrophosphates as essentia

118 ogy remains poorly understood, with emerging evidence implicating interactions between diverse immune

119 There is compelling evidence implicating intestinal permeability in the path

120 This review discusses the emerging evidence implicating intrahepatic B cells in the progres

121 lerosis (MS) susceptibility; however, strong evidence implicating intrinsic and environmental factors

122 There is an emerging body of evidence implicating iron in carcinogenesis and in parti

123 rmation tropism in vitro and provides strong evidence implicating its contribution to the distinct pa

124 e alloimmune response, there is considerable evidence implicating lipoprotein abnormalities, metaboli

125 Our study provides biomechanical evidence implicating lower PTSs combined with internal m

126 consistent with genetic and cell biological evidence implicating LPPs as negative regulators of lyso

127 se results are convergent with immunogenetic evidence implicating lymphoid cell dysregulation in depr

128 ies functional heterogeneity consistent with evidence implicating lymphoid DCs in the negative select

129 obable, or possible according to strength of evidence implicating M. pneumoniae.

130 Here we discuss recent evidence implicating macrophages in HIV-1-mediated disea

131 These results provide further evidence implicating MAPK signaling factors as obligate

132 fusion in CHR-P individuals, consistent with evidence implicating medial temporal GABAergic dysfuncti

133 Despite a growing body of evidence implicating membrane interaction in IAPP toxici

134 brain tissue compartment and provide in vivo evidence implicating meningeal inflammation in the patho

135 Although there is strong evidence implicating MHC class II alleles and CD4(+) T c

136 In light of recent evidence implicating miR132 dysregulation in Rett syndro

137 In summary, this work provides direct evidence implicating miRNA in the process of turning on

138 have a functional ancestor in MreB based on evidence implicating MreB as an organizer of cell wall s

139 This review will discuss the evidence implicating mRNA translation as an important do

140 Clinical evidence implicating mucosal allergic responses in dysmo

141 Together, our study provides human genetic evidence implicating multiple glial cell types in AD pat

142 Here we present evidence implicating mutations in the gene encoding alph

143 These findings extend the body of evidence implicating mutations in the hairless gene as a

144 Despite strong biochemical evidence implicating NAIPs in specific detection of bact

145 Here, we provide evidence implicating NaV dysregulation within transverse

146 In this Review, we outline the evidence implicating necroptosis in these neurological d

147 In particular there is fairly direct evidence implicating neuronatin in the causation of Lafo

148 nt genetic, pharmacological and neuroimaging evidence implicating neuropathology associated with psyc

149 This review discusses the evidence implicating neurotrophins as molecular mediator

150 el roles for NF-kappaB, together with recent evidence implicating NF-kappaB in the regulation of neur

151 ry and chronic kidney disease, with emerging evidence implicating NK cell-derived mediators in fibrog

152 Despite accumulating evidence implicating noncoding variants in human disease

153 There is considerable functional evidence implicating norepinephrine in modulating activi

154 These results provide direct evidence implicating O2(-) generation in the pathway to

155 Despite the compelling evidence implicating OBSCN loss in breast tumorigenesis

156 al sclerosis (ALS), case-control statistical evidence implicating oligogenicity with disease risk or

157 hese data represent the first line of direct evidence implicating one of the organic anion transporte

158 uent children in these families, and provide evidence implicating other genes in syndromic CS.

159 tinnitus is unclear, especially in light of evidence implicating other networks, including the limbi

160 Evidence implicating oxidative stress in the pathogenesi

161 Evidence implicating p38gamma and p38delta (p38gamma/p38

162 Genetic evidence implicating packaging elements as independent u

163 Although in animals there is direct evidence implicating particular miRNAs in the control of

164 We found little to no genomic evidence implicating pathogens in the species' decline a

165 Our findings provide the first causal evidence implicating PCC in memory encoding and highligh

166 Whereas the epidemiologic evidence implicating PDGF in human tumors is strong, mal

167 imental atherosclerosis and provide indirect evidence implicating PDGF-BB and Sp1 as possible mediato

168 Recent studies provide strong evidence implicating Peptostreptococcus micros in the pa

169 Though there is compelling circumstantial evidence implicating PFO, the precise role of PFO in the

170 hermore, these studies provide important new evidence implicating PI 3-K in the regulation of integri

171 The evidence implicating PKA has come from bath application

172 Evidence implicating plasminogen (Plg), the zymogen of p

173 In this review, the evidence implicating PLD and PA in the regulation of mTO

174 When combined with recent evidence implicating Pol epsilon in leading strand repli

175 Although there is considerable evidence implicating posttranslational mechanisms in the

176 These results provide strong evidence implicating PP1 function in meiosis.

177 Our results are consistent with emerging evidence implicating PPC dysfunction in WM impairment an

178 These findings add to the evidence implicating prefrontal dysmaturation in this di

179 There is accumulating evidence implicating prolonged ER stress in the developm

180 Finally, we provide an overview of recent evidence implicating proteins of the early secretory pat

181 These results provide the first definitive evidence implicating Ptp4a3 in colon tumorigenesis and h

182 in BXH-2 acute myeloid leukemia is the first evidence implicating Rap1 signaling in myeloid leukemia.

183 Despite extensive evidence implicating Ras in cardiac muscle hypertrophy,

184 conclude that although there is significant evidence implicating Ras, RhoA, and Rac1 in hypertrophy,

185 Here, we present genetic and molecular evidence implicating RCI1A in the response to low temper

186 Evidence implicating reentry as a mechanism of cardiac a

187 ly, they lend support to an emerging line of evidence implicating regions of the default mode network

188 This report provides the first evidence implicating roles for hepatic TSLP signaling, t

189 These data support evidence implicating RyRs as targets in environmentally

190 enance of synaptic connections and to obtain evidence implicating S100 beta in the apparent neurotrop

191 lts are, to our knowledge, the first genetic evidence implicating sarcomere-associated formins in the

192 with auxin-mediated cell expansion, genetic evidence implicating SAURs in cell expansion has not bee

193 This review summarizes the evidence implicating SCD in cancer progression and propo

194 sustained mechanical forces, with increasing evidence implicating Schwann cells as key mediators.

195 lication divergence dates provide additional evidence implicating segmental duplications as a major m

196 precisely localized deletion provides direct evidence implicating segmental exchange of MHC-encoded D

197 Further, we review evidence implicating sensation as a rapid and relatively

198 consistent with behavioral and physiological evidence implicating serotonin as an inhibitory modulato

199 This review discusses recent evidence implicating serotonin in the development of exp

200 on were studied to corroborate pharmacologic evidence implicating SERT in 2'-NH(2)-MPTP-induced serot

201 e-scale genetic studies have provided robust evidence implicating several novel susceptibility genes

202 sequencing study provides strong functional evidence implicating several specific variants as primar

203 Compelling evidence implicating SnToxA and SnTox1 in disease develo

204 These results add to the evidence implicating soil ameboid predators as important

205 There is emerging evidence implicating soluble oligomers, smaller protein

206 China, but this conflicts with phylogenetic evidence implicating southwestern China as the centre of

207 provides the opportunity to seek convergent evidence implicating specific chromosomal segments and g

208 Absence of evidence implicating specific food or beverage sources a

209 Given the accumulating evidence implicating Src family kinases in the transduct

210 Much of the evidence implicating Stats in these cellular processes c

211 The evidence implicating sun exposure in the etiology of mel

212 eural crest development are reviewed and the evidence implicating TBX1 and other genes on chromosome

213 There is substantial in vitro and in vivo evidence implicating tea polyphenols as chemopreventive

214 Accumulating evidence implicating telomere damage as a driver of age-

215 Despite evidence implicating TGFalpha in the development of mamm

216 sm for motor and sleep pathophysiology, with evidence implicating thalamic and brainstem structures a

217 These data provide evidence implicating that the truncated form of GGA1 beh

218 These data are intriguing given growing evidence implicating the 5-HTT in the pathophysiology an

219 Herein, we review the mounting evidence implicating the AKT pathway in the aggregate of

220 In a previous investigation, we obtained evidence implicating the alpha4/5 region of the type A d

221 We present evidence implicating the ANK repeats in the regulation o

222 We present evidence implicating the BAF (BRG1/BRM Associated Factor

223 Their findings further provide evidence implicating the basonuclin 2 (BNC2) gene in EOC

224 Mechanistically, we present evidence implicating the BBSome in the trafficking of G

225 These findings provide additional evidence implicating the behavior of the ribosome transl

226 Furthermore, we present evidence implicating the bifunctional, Hh signaling comp

227 Despite growing evidence implicating the calcium-activated chloride chan

228 This provides further evidence implicating the cerebellum in cognition and sug

229 Here we present evidence implicating the DNA methylation program in the

230 Despite epidemiologic evidence implicating the early-life environment in the r

231 Our data provide strong evidence implicating the ER-to-Golgi traffic as a site f

232 om the ER to the Golgi and provide the first evidence implicating the ER-to-Golgi transport as a regu

233 These findings provide strong evidence implicating the excitatory system within hippoc

234 responsible for this important function, and evidence implicating the GBM is largely ignored or forgo

235 There is increasing evidence implicating the human NF1 gene in epithelial ca

236 acks of weakness and add support to previous evidence implicating the IIS4 voltage sensor in slow-ina

237 We review evidence implicating the increase of intracellular sodiu

238 These findings add to the body of evidence implicating the intestinal epithelium in key as

239 , Gonzalez-Villalobos et al. present further evidence implicating the intrarenal renin-angiotensin sy

240 ation, which is consistent with accumulating evidence implicating the IPS in structuring sensory inpu

241 We also present evidence implicating the Lhx6 and Lhx7 LIM-homeobox gene

242 These findings substantiate and enrich the evidence implicating the locus coeruleus in cellular asp

243 eview provides a perspective of the emerging evidence implicating the LT Network in the development a

244 Given recent evidence implicating the medial prefrontal cortex in ret

245 ntestinal barrier function, given the recent evidence implicating the microbiome, diet, and mucosal i

246 We provide substantial evidence implicating the multienzyme aminoacyl-tRNA synt

247 We now provide evidence implicating the neuregulin (NRG)-erbB receptor

248 Here, we show evidence implicating the nitric oxide (NO)/cGMP signalin

249 Here we present genetic and functional evidence implicating the novel A178D missense mutation i

250 Here we review evidence implicating the orbitofrontal cortex in such be

251 r, the protein was hyperphosphorylated, with evidence implicating the p38/mitogen-activated protein k

252 Our findings offer causal evidence implicating the PCC in episodic memory encoding

253 Here, we provide evidence implicating the planar cell polarity (PCP) path

254 Despite evidence implicating the Polycomb group protein, Eed (em

255 To date, despite the mounting evidence implicating the potential diagnostic/prognostic

256 s and footshock and add to a growing body of evidence implicating the rhinal cortical regions in asso

257 These findings add to the growing body of evidence implicating the RNA processing pathway in neuro

258 There is evidence implicating the role of female sex hormones as

259 itional multivoxel pattern analyses revealed evidence implicating the rostrolateral PFC in the repres

260 We have previously presented evidence implicating the side chains of L8, I44, and V70

261 herent cortical rhythms and provides further evidence implicating the syllable as a computational pri

262 The present study provides multiple lines of evidence implicating the tumor suppressor protein p53 in

263 Here, we present evidence implicating the two-pore domain, pH-sensitive T

264 Here we present two lines of evidence implicating the ubiquitin-proteasome pathway in

265 Given recent evidence implicating the urokinase plasminogen activator

266 renia, and family-based studies found modest evidence implicating the Val allele in schizophrenia ris

267 (fMRI) data from human volunteers, we found evidence implicating the ventrolateral prefrontal cortex

268 The finding converges with recent evidence implicating the VMPFC in emotional and autonomi

269 , Aspergillus fumigatus, based on increasing evidence implicating the yeast metacaspase Yca1p in apop

270 d clinicians alike because of the increasing evidence implicating their role in many biological proce

271 the last few years because of the increasing evidence implicating them as key regulators of the choic

272 e (ICE) protease family has led to extensive evidence implicating these enzymes in apoptosis.

273 al functions and, in particular, we focus on evidence implicating these processes in the molecular pa

274 ar particularly noteworthy based upon recent evidence implicating these structures in the generation

275 pment; however, there is little experimental evidence implicating this cellular mechanism in the path

276 f EBNA3C with ProTalpha and p300 provide new evidence implicating this essential EBV protein EBNA3C i

277 lular visual pathway, consistent with recent evidence implicating this pathway in fine-grained stereo

278 Lesion studies of the EC provide evidence implicating this region as critical for memory

279 Additional evidence implicating this region in linguistic processin

280 o expend effort for rewards, consistent with evidence implicating this region in the processing of re

281 ther, these findings reveal first systematic evidence implicating TLR9 as one of the drivers of perio

282 r results provide the first proof-of-concept evidence implicating TLR9-triggered inflammation in peri

283 is may be relevant for the growing amount of evidence implicating TORC2 in cancer development.

284 Recent evidence implicating transmembrane (TM) segment 7 of the

285 we present integrative RNA, DNA, and protein evidence implicating TREML4 in coronary artery calcifica

286 Now, as result of molecular evidence implicating two separate ligand-gated calcium c

287 Direct evidence implicating upstream signals and components tha

288 dy provides the first genomewide significant evidence implicating variants near the ADM gene on chrom

289 The accumulation of preclinical and clinical evidence implicating VEGF-A in the pathogenesis of neova

290 However, most evidence implicating VTA DA neurons in these functions i

291 Here, we describe evidence implicating WT1, the 11p15 locus, and the recen