ライフサイエンスコーパス: evolutionary

1 MDMs' pro-inflammatory response is likely an evolutionary accident.

2 g the impact of WGD events on speciation and evolutionary adaptation.

3 rance, acclimation capacity, and ability for evolutionary adaptation.

4 rganized into a limited set of dimensions by evolutionary adaptation.

5 Animals display wide-ranging evolutionary adaptations based on their ecological niche

6 Evolutionary adaptations of temporo-parietal cortex are

7 ppear driven by natural enemies, diseases or evolutionary adaptations that selectively reduce populat

8 However, little is known about their evolutionary adaptations to these highly structured but

9 RAG2, a late evolutionary addition in V(D)J recombination, appears to

10 score the importance of their function as an evolutionary advantage and that of the H2-T6SS as the me

11 hat is not contingent on sleep may confer an evolutionary advantage.

12 s work, we address this issue by means of an evolutionary agent-based model that incorporates fights

13 urthermore, we review models and methods for evolutionary analyses of CNAs from scDNAseq data and hig

14 However, recent evolutionary analyses of mammals, plants, and flies repo

15 Evolutionary analyses show that in 17 out of 19 cases, t

16 ing any single phenotype could have negative evolutionary and demographic consequences, potentially r

17 important as instrumental for understanding evolutionary and ecological processes in the wild.

18 This study provides an unbiased evolutionary approach to non-invasively delineate clonal

19 The co-evolutionary arms race between predators and their prey

20 rage fish, in contrast, have been engaged in evolutionary arms races with their predators for more th

21 ation into phylogenomic context, thus making evolutionary based protein function analysis more effici

22 In the constant evolutionary battle against mobile genetic elements (MGE

23 c and plays putative roles governing certain evolutionary behaviours and mood modulation.

24 The coordination mechanism and possible evolutionary benefits of neutrophil swarms are elusive.

25 rimental methods for synthetic, systems, and evolutionary biology and broadens access to cutting-edge

26 as provided a rich source of information for evolutionary biology and engaged considerable public int

27 Rank orders have been studied in evolutionary biology for almost a hundred years.

28 can present epidemiological, ecological, and evolutionary challenges.

29 e largely architectural, and it appears that evolutionary change involved changes in protein-protein

30 sons to mobilize and modify genomes, driving evolutionary change without substantially affecting repr

31 es, TrackSig permits pan-cancer insight into evolutionary changes in mutational processes.

32 sharing ontogenetic pathways, making certain evolutionary changes less likely.

33 ll phosphate-binding protein lineages in the Evolutionary Classification of Protein Domains database.

34 d be one of the molecular mechanisms seeding evolutionary co-option.

35 and gene blocks provide a model of tractable evolutionary complexity at the genomic level.

36 rovide to the offspring is complicated by an evolutionary conflict of interest ('sexual conflict') be

37 However, the long-term evolutionary consequences of decreased parasite exposure

38 or breeding programs, and for predicting the evolutionary consequences of domestication-introgression

39 The observation of extensive evolutionary conservation in copper homeostatic systems

40 , the purine salvage enzyme HPRT, suggesting evolutionary conservation in different enzymes.

41 eceptors are at least partially dependent on evolutionary conservation in the structure and nature of

42 Considering the evolutionary conservation of ARFs and ARF-GEFs, this ini

43 with a loss of fertility, demonstrating the evolutionary conservation of flagellar function related

44 Evolutionary conservation of the core Hh signaling pathw

45 eutral, perhaps unexpectedly in light of its evolutionary conservation.

46 protein-protein interfaces and a measure of evolutionary conservation.

47 Such goal-directed behavior involves evolutionary conserved brain structures like the striatu

48 sphate-activated protein kinase (AMPK) is an evolutionary conserved serine/threonine kinase that inte

49 In addition, these results deserve further evolutionary considerations regarding potential benefits

50 However, the causes of evolutionary constraint have remained elusive due to a p

51 F1 pathway, and immunity are under increased evolutionary constraint in large and long-lived mammals.

52 onally, this generalization of ET shows that evolutionary constraints among sequence, structure, and

53 deleterious in another, indicating that the evolutionary constraints of antigenic site B have change

54 We explore a range of ecological and evolutionary constraints under which stability of a popu

55 ture-oriented cognition, and they provide an evolutionary context for patterns of social aging in hum

56 utionary history of these channels to add an evolutionary context to the already available physiologi

57 However, the evolutionary correlations between P50 and psi(min) and b

58 a combination of thermodynamic stability and evolutionary covariation information.

59 4), evolutionary radiations themselves cause evolutionary decay (modelled co-occurrence probability a

60 f the inversions, potentially mitigating the evolutionary degeneration expected at genomic regions th

61 etect up to two-thirds of cell-type-specific evolutionary differences.

62 n via blastocyst complementation across wide evolutionary distances.

63 Thus, evolutionary divergence across space might frequently in

64 We identified evolutionary divergence in the DNA methylation profiles

65 To explore the evolutionary divergence of diatoms, additional model spe

66 s-specific cell subtypes suggesting possible evolutionary divergence.

67 tion regimes, and that there is a decline in evolutionary diversity above 1,490 mm of mean annual rai

68 Rather, our results show that the greatest evolutionary diversity is found in intermediate precipit

69 We find a marked reduction in the evolutionary diversity of communities at low precipitati

70 Here we detail how evolutionary diversity varies along precipitation gradie

71 If conservation is to prioritise evolutionary diversity, areas of intermediate precipitat

72 sleep architecture raise questions about the evolutionary drivers of sleep behavior.

73 Here we show ecological-evolutionary dynamics between parasitoids and aphids con

74 challenging, and it is thus unclear how eco-evolutionary dynamics drive the evolution of constituent

75 Here, we explore general evolutionary dynamics for arbitrary spatial structures a

76 Control can alter the eco-evolutionary dynamics of a target pathogen in two ways,

77 Our results highlight the distinct evolutionary dynamics of live attenuated virus vaccines

78 is likely to provide novel insight into the evolutionary dynamics of repetitive elements.

79 Here we investigate the evolutionary dynamics of several kinds of modern cultura

80 species contribute to the establishment and evolutionary dynamics of TAD boundaries.

81 s on the Darwinian processes driving the eco-evolutionary dynamics of treatment-resistant cancer popu

82 contribute to a deeper understanding of the evolutionary dynamics resulting from biotic interactions

83 tasis are widespread in nature and can shape evolutionary dynamics.

84 gether generate self-perpetuating ecological-evolutionary dynamics.

85 rostatic charge with immune escape and viral evolutionary dynamics.

86 among the most widely-studied quantities in evolutionary dynamics.

87 Osiurak and Reynaud do not explain the evolutionary emergence and development of the elephant i

88 ct features of PD-L2 and identify a specific evolutionary event linked to its appearance.

89 We reconstructed the evolutionary events leading to this gene cluster and fou

90 We find that these uniquely replicated evolutionary events support the idea that co-obligate as

91 We reconstruct the evolutionary events that followed the acquisition of STI

92 gether, these data reveal the workings of an evolutionary fail-safe, a duplicate enhancer mechanism t

93 The evolutionary features and molecular innovations that ena

94 Eco-evolutionary feedbacks may help to understand changes in

95 ghlight that local selection is an important evolutionary force in natural tree populations and sugge

96 her, our findings show how HGT can act as an evolutionary force that facilitates the spread of nonsel

97 g of both functional roles and the mosaic of evolutionary forces acting on loci.

98 By quantifying multiple evolutionary forces acting on sPTB-associated regions, o

99 For same-sex marriage, evolutionary forces have grown in relative importance as

100 x, in part due to interacting ecological and evolutionary forces in the microbiome.

101 led the importance of various ecological and evolutionary forces shaping plant microbiota.

102 triguing variation exists that speaks to the evolutionary forces that have shaped the endomembrane sy

103 Our findings accelerate the understanding of evolutionary forces underpinning metazoan life at the li

104 Our studies provide an evolutionary framework for investigating complex relatio

105 ndividual ecophysiological behaviour and its evolutionary gain would increase our understanding on ho

106 Inspired by the evolutionary game theory, we formulated a bi-level optim

107 es and b is a GB variant), in agreement with evolutionary GB structure search and clustering analysis

108 otypical traits remains a major challenge in evolutionary genetics.

109 Evolutionary genomic analyses revealed that these isolat

110 Cancer development is an evolutionary genomic process with parallels to Darwinian

111 Evolutionary genomic studies find that reproductive prot

112 y expressed in the reproductive tissue using evolutionary genomics.

113 ods infer large solution spaces of plausible evolutionary histories from the same sequencing data, ob

114 s encode complex metabolic capabilities with evolutionary histories largely independent of cellular l

115 ate sixteen pipelines for reconstructing the evolutionary histories of 293 localized prostate cancers

116 phenotypic impact of genetic variation, the evolutionary histories of most variants are largely unex

117 hood (MPL), a method to infer selection from evolutionary histories that resolves genetic linkage.

118 d K. hermaphroditus had remarkably different evolutionary histories when colonising the same mangrove

119 of their high level of diversity and complex evolutionary histories, most studies on plant receptor-l

120 Here, we reconstructed their evolutionary history across the speciation continuum.

121 , tradeoffs depend on genetic background and evolutionary history and can themselves evolve.

122 lent HIV-1 in several features including its evolutionary history and certain aspects of viral replic

123 ution of genetic instability and infer tumor evolutionary history from experimental data.

124 genome is currently lacking, and the group's evolutionary history is not fully resolved.

125 Its evolutionary history is similar to that of bread wheat,

126 across all major lineages, reconstructed the evolutionary history of cranial hyperossification across

127 This group appears pivotal to the subsequent evolutionary history of forests due to possession of mul

128 ineages, are needed to better understand the evolutionary history of ICA's diverse biotas.

129 Thermoplasmata and provide insight into the evolutionary history of methanogenesis within the Ca.

130 This evolutionary history of P. xylostella provides insights

131 vaccine design are unique and tied to the co-evolutionary history of the pathogen and humans, but the

132 In this study, we investigated the evolutionary history of these channels to add an evoluti

133 These findings provide insights into the evolutionary history of wintersweet and the relationship

134 n and dispersal events throughout a species' evolutionary history often remains elusive.

135 or of body nutrient content, indicating that evolutionary history plays a crucial role in determining

136 ences in chromosome organization, phenotype, evolutionary history, sperm morphology and genetic, whic

137 ungi have faced relatively recently in their evolutionary history.

138 e subpopulations in a sample and infer their evolutionary history.

139 e understanding of both plastid function and evolutionary history.

140 s, uncover this signal, and accurately infer evolutionary history.

141 Little is known about its evolutionary history.

142 Here, we show that hurricanes have enduring evolutionary impacts on the morphology of anoles, a dive

143 The possible evolutionary implications of the loss of a dedicated olf

144 e interrelationship, the inhibitors, and the evolutionary implications of the RSV polymerase.

145 example management tools and their potential evolutionary implications-both their opportunities for a

146 neral concept of redundancy and focus on the evolutionary importance of redundancy in terms of the nu

147 broad-scale analysis highlights the overall evolutionary importance of the geophytic habit (i.e. bel

148 ly old interneuron types, complemented by an evolutionary increase in principal neuron diversity.

149 Evolutionary innovations allow populations to colonize n

150 Our results are consistent with rare evolutionary innovations in cold acclimation ability str

151 g quality and quantity of whole-genome data, evolutionary insight into origins of distinct plant grou

152 and between K(s) and Hv show signs of deeper evolutionary integration because of functional, developm

153 However, the evolutionary interactions between antibiotics and phages

154 and predictive biology that accounts for eco-evolutionary interactions in both space and time.

155 ellular, evo-devo, synthetic biological, and evolutionary investigations.

156 engineering attempts, and propose how to use evolutionary knowledge to advance future research in the

157 s to the species, and we discuss a potential evolutionary link between H. naledi and hominins from St

158 utive PTEN expression slow transcription, an evolutionary mechanism that may save cellular energy and

159 o be associated with distinct regulatory and evolutionary mechanisms.

160 The evolutionary model was optimized using a nonlinear mixed

161 ast cancer data revealed a linear, branching evolutionary model with two distinct trajectories for ma

162 sponding phenotype-is generally neglected in evolutionary models, yet recent work suggests that it ma

163 The evolutionary modification of development was fundamental

164 the arcuate fasciculus underwent additional evolutionary modifications affecting the temporal lobe c

165 mental or genetic constraints, conforming to evolutionary modules.

166 -associated centromeres and establishment of evolutionary new centromeres (ENCs) in C. albicans.

167 ry networks (GRNs) indeed underlies numerous evolutionary novelties.

168 rgence is a major driver in the emergence of evolutionary novelties.

169 diazotrophic Frankia spp. bacteria share an evolutionary origin about 110 million years ago.

170 However, the evolutionary origin and the relative role of neural spec

171 n Guyana, with genome analysis indicating an evolutionary origin distinct from Southeast Asia.

172 cated that the nodulation trait has a shared evolutionary origin in all 10 lineages.

173 is essential to understand their role in the evolutionary origin of developmental novelties.

174 However, little is known about the evolutionary origin of these neurons and their interacti

175 gests they form a distinct clade with common evolutionary origin.

176 known about stomata in bryophytes, and their evolutionary origins and ancestral function remain poorl

177 tigations for phylogenetic constructs of the evolutionary origins of culture.

178 The evolutionary origins of how modern humans share and use

179 findings have implications not only for the evolutionary origins of SSB, but also for the evolution

180 Here we reveal the evolutionary origins of the chemosensory machinery that

181 e integration preferences of specific TEs on evolutionary outcomes and the effects of different selec

182 irectly via gene regulation, and may suggest evolutionary outcomes of retroviral endogenization.

183 lution, speciation, and other ecological and evolutionary outcomes.

184 al tree modeling is essential for estimating evolutionary parameters in population genetics and phylo

185 The evolutionary parameters optimized for each patient indic

186 Further, we find that the length of an evolutionary path strongly correlates to its increase in

187 ecules with catalytic capability began their evolutionary path toward self-replication.

188 s landscapes, which have the power to reveal evolutionary paths and inform evolution of desired funct

189 near-complete sequences show that different evolutionary paths of genotypic host adaptation resulted

190 e same sequencing data, obfuscating repeated evolutionary patterns.

191 ents will facilitate the description of LUAD evolutionary patterns.

192 From an evolutionary perspective, sensing danger is essential fo

193 eir cancer-derived somatic mutations from an evolutionary perspective.

194 idely studied from genetic/developmental and evolutionary perspectives.

195 duced labiate process on its valve; and this evolutionary position is robustly supported by multigene

196 mplexity integrating interaction network and evolutionary potential approaches.

197 work provides a blueprint for investigating evolutionary pressures on complex traits.

198 are reminiscent of genetic accommodation, an evolutionary process by which phenotypic flexibility in

199 pecific for the pathogen through a Darwinian evolutionary process known as affinity maturation.

200 mediate regime shift but instead triggers an evolutionary process that drives a phenotypic trait beyo

201 on depends on the specific mechanisms of the evolutionary process.

202 ains; however, we know very little about how evolutionary processes (natural or artificial) might hav

203 e effects of pulse warming on ecological and evolutionary processes are complex and context dependent

204 population genomic analyses for gauging the evolutionary processes governing genetic variation in na

205 r epidemiology is critical to understand the evolutionary processes maintaining the success of the BA

206 Our results show differing evolutionary processes on the three segments that compri

207 ediated by small RNAs may thus contribute to evolutionary processes over a short timescale but are un

208 of real landscapes shapes the ecological and evolutionary processes that determine species range edge

209 However, the genetic bases and evolutionary processes underlying this 'molecular divers

210 ng apart the role of neutral and non-neutral evolutionary processes.

211 ate in a predictable manner-through parallel evolutionary processes.

212 tural laboratories for the study of parallel evolutionary processes.

213 iation is essential for the understanding of evolutionary processes.

214 ow its many dimensions impact ecological and evolutionary processes.

215 We aimed to identify the different evolutionary profiles of CAV and to determine the respec

216 By examining the evolutionary properties of gene-flanking regions on the

217 rom being integrated more explicitly with an evolutionary psychological perspective.

218 Multifunctional proteins are evolutionary puzzles: how do proteins evolve to satisfy

219 ered flight(1) and comprised one of the main evolutionary radiations in terrestrial ecosystems of the

220 Moreover, in addition to extinctions(4), evolutionary radiations themselves cause evolutionary de

221 Bayesian evolutionary rate and divergence date estimates were sho

222 properties are tightly coupled with protein evolutionary rate, depending on whether and how gene dup

223 r chronological gaps between periods of high evolutionary rates (phenotypic and molecular) and expans

224 nd for two different prior specifications of evolutionary rates based on HCoV-OC43 and MERS-CoV.

225 er, these dynamics created both the distinct evolutionary record of metazoan groups during the Cambri

226 ctional determinants, we seek to exploit the evolutionary record of variation and divergence read fro

227 However, available tools frequently ignore evolutionary relations among microbial taxa, potential r

228 cell death reaction, further supporting the evolutionary relationship between gasdermin and rcd-1 Th

229 Likewise, through phylogenetic analysis, the evolutionary relationship of subgroups was determined, d

230 BjuGalpha1 genes share a close evolutionary relationship, and the encoded proteins exhi

231 tabase and MS we determined the composition, evolutionary relationships and hence predicted functions

232 h mitochondrial and nuclear genomes to infer evolutionary relationships and potential patterns of int

233 tive of proteomic, structural, regulatory or evolutionary relevance and integrate them into a single

234 subsequent genetic adaptation and promoting evolutionary rescue.

235 dy underscores the importance of integrating evolutionary responses in realistic ecotoxicological ris

236 these 3 types when projecting ecological and evolutionary responses of populations and of biodiversit

237 Instead, individualistic evolutionary responses to Pleistocene climatic fluctuati

238 essive functional changes; we consider these evolutionary "rheostats".

239 torical roots in hypoxia emphasize a broader evolutionary role.

240 ertebrates will reveal information about the evolutionary roots of this major signaling pathway, will

241 We propose an evolutionary scenario beginning with pathogen-associated

242 ies traits are widely used in ecological and evolutionary science, and new data and methods have prol

243 rsity, the cell-to-cell variation that fuels evolutionary selection also manifests in cellular states

244 more, using seed site randomized genomes and evolutionary selection experiments, we found that tropis

245 A hypothesis for the evolutionary selection of ddl containing integron gene c

246 Our work shows how evolutionary selection pressure can cause proteins with

247 Given the evolutionary separation between macaques and marmosets,

248 Here we identify a nontransitive evolutionary sequence in a 1000-generation yeast evoluti

249 nce space sampled by RECON MSD resembled the evolutionary sequence space of flexible proteins, partic

250 pattern of divergence implies occasional co-evolutionary shifts in how plants interact with soil mic

251 ssignment of Management Unit (MU) status and Evolutionary Significant Units (ESUs) based on phylogeog

252 o the scaffold domain of TBK1, suggesting an evolutionary similarity between the autophagy-initiating

253 A theoretical analysis reveals multiple evolutionary stable network structures that depend on th

254 d GSH and IFD strategy that may represent an evolutionary stable state.

255 Thus, from an evolutionary standpoint, some high-risk childhood cancer

256 While the evolutionary steps leading to the derived activity are s

257 ent STM strains and directed edges represent evolutionary steps, presenting evidence that the structu

258 We also observe an evolutionary Stokes shift in the fitness of sequences th

259 sex chromosome evolution, in which distinct evolutionary strata reflect an expanding region of suppr

260 pression beyond mating-type genes in fungi ('evolutionary strata'), which have been little studied an

261 t-for-tat retaliation is a surprisingly poor evolutionary strategy, because tit-for-tat cells lack th

262 ng density functional theory coupled with an evolutionary structure-predicting algorithm.

263 k of genomic resources for Dalbergia hinders evolutionary studies and conservation applications, whic

264 isms that have traditionally been applied in evolutionary studies.

265 smission, we identified indicators of future evolutionary success for an emerging antigenic cluster a

266 This evolutionary success is largely attributed to neck elong

267 reproductive outcome is directly coupled to evolutionary success, the underlying mechanisms are unde

268 utionary processes made the genus Quercus an evolutionary success.

269 ness and create the conditions necessary for evolutionary success.

270 range of signaling pathways across different evolutionary taxa.

271 Evolutionary theory predicts that, following successful

272 hes are entirely data driven and agnostic to evolutionary theory.

273 ude hypoxia, but some changes require longer evolutionary time to arise.

274 d have been driven by fear of predation over evolutionary time.

275 Constraint-breaking adaptations are evolutionary tools that provide a mechanism for incumben

276 articular, whether and when phages can drive evolutionary trade-offs with antibiotic resistance.

277 These differential evolutionary trajectories are accompanied by gene-family

278 onal architecture analyses present congruent evolutionary trajectories for SCNAs and DNA methylation

279 Such repeated evolutionary trajectories hold the potential to improve

280 ae, and that these bones underwent divergent evolutionary trajectories in placoderms and osteichthyan

281 recruitment cue layered atop of the distinct evolutionary trajectories of wild and domesticated plant

282 Our evolutionary trajectories reached a plateau at the level

283 nditions under global change will impact the evolutionary trajectory of floral traits.

284 ow loss of parasite diversity influences the evolutionary trajectory of the vertebrate immune system,

285 s, and adaptive responses that highlight the evolutionary trajectory toward terrestrialization.

286 ewly-encountered substrates to influence the evolutionary trajectory, an aspect that is often overloo

287 mutations define a functionally reproducible evolutionary trajectory.

288 The development of multicellularity is a key evolutionary transition allowing for differentiation of

289 rovides an opportunity for understanding the evolutionary transition from an aerobic to an exclusive

290 To which extent evolutionary transitions between life-cycle strategies a

291 domestication trade-off across the major co-evolutionary transitions in the farming systems of attin

292 a key role in the origins of life and other evolutionary transitions.

293 adaptation into maladaptation, resulting in evolutionary traps.

294 zation of different tracts along the primate evolutionary tree, including distinctive connectivity of

295 bels unlock opportunities in the analysis of evolutionary trees.

296 o-option of dsx as a mimicry locus, and that evolutionary turnover of dsx alleles may underlie the wi

297 This implies that evolutionary turnover of the mammalian stem lineage duri

298 nes of other blow flies will allow a refined evolutionary understanding of how flies with a typical X

299 ollowed by new treatments to exploit the eco-evolutionary vulnerability of small and/or declining pop

300 scale the gray zone of speciation, i.e., the evolutionary window separating widely admixing lineages