ライフサイエンスコーパス: evolutionary change

1 permits them to shift location as a part of evolutionary change.

2 hly conserved, it is uniquely susceptible to evolutionary change.

3 rsification can be overcome by ecological or evolutionary change.

4 species to understand the genetic basis for evolutionary change.

5 nderscore the need to link macroecology with evolutionary change.

6 istatic interactions can frustrate and shape evolutionary change.

7 h changes in numbers or size structure cause evolutionary change.

8 ies and creating a cascade of ecological and evolutionary change.

9 ions, a property that seems contradictory to evolutionary change.

10 process, is dominated by events of concerted evolutionary change.

11 heritable disease and the ultimate source of evolutionary change.

12 vel environment to directing the patterns of evolutionary change.

13 r a window into the genetic underpinnings of evolutionary change.

14 reate a time void which could aid additional evolutionary change.

15 erved and thus considered to be resistant to evolutionary change.

16 ems can evolve to both promote and constrain evolutionary change.

17 three species can enhance the potential for evolutionary change.

18 for understanding the developmental basis of evolutionary change.

19 al factors can instruct our understanding of evolutionary change.

20 n may be a general mechanism contributing to evolutionary change.

21 regulation are also the most susceptible to evolutionary change.

22 ng diversity into a population and promoting evolutionary change.

23 ate but not be absolutely required for rapid evolutionary change.

24 mense potential to address the mechanisms of evolutionary change.

25 ge and environmental deterioration caused by evolutionary change.

26 lar phylogenies suggest smoother patterns of evolutionary change.

27 oth condition-dependent and subject to rapid evolutionary change.

28 s therefore expected to provide insight into evolutionary change.

29 s unclear if this was owing to plasticity or evolutionary change.

30 ions, particularly under conditions of rapid evolutionary change.

31 rations in regulatory networks contribute to evolutionary change.

32 nt understanding of the mechanistic basis of evolutionary change.

33 a functional consequence of this structural evolutionary change.

34 purely phenotypic estimates of selection and evolutionary change.

35 studies help us understand the processes of evolutionary change.

36 trict version of stasis that entails no real evolutionary changes.

37 al view, point centromeres can undergo rapid evolutionary changes.

38 the face of unpredictable environmental and evolutionary changes.

39 gulatory elements undergoes subtype-specific evolutionary changes.

40 subgroup of a species may lead to important evolutionary changes.

41 asts of higher plants has undergone dramatic evolutionary changes.

42 edictability underlying the genetic basis of evolutionary changes.

43 terns of neurodevelopmental expansion mirror evolutionary changes.

44 As (miRNAs) have the potential to facilitate evolutionary change [1-3]; however, there are no known e

45 uses are one of the most dominant drivers of evolutionary change across mammalian and human proteomes

46 y, we evaluated the extent of both long term evolutionary changes, across the mammalian phylogeny of

47 owever, if a stock is managed optimally, the evolutionary changes actually increase economic yield be

48 f which exhibited a greatly elevated rate of evolutionary change and a dramatic breakdown of temporal

49 species, gain insight into the direction of evolutionary change and assess whether breakpoint region

50 genetic conflict, are an important motor for evolutionary change and innovation.

51 Mutations stimulate evolutionary change and lead to birth defects and cancer

52 Although rates of evolutionary change and selection pressures varied among

53 ecord of composition, potentially clarifying evolutionary changes and biotic responses to paleoenviro

54 sity through which adaptation may facilitate evolutionary changes and shape developmental regulatory

55 g on the phylogeny was conducted to identify evolutionary changes and to assess the correlation betwe

56 y common situation in changing environments: evolutionary changes are not strong enough to fully comp

57 Such evolutionary changes arise either through alterations of

58 rapid evolution, but it is not known whether evolutionary changes arise mainly after successful colon

59 testing whether these genes experience rapid evolutionary change as a result of conflict over spore-s

60 gists and biochemists, who used experimental evolutionary change as a tool to understand structure-fu

61 complexities of the Bologna process and its evolutionary changes as it relates to nursing education

62 provide an original example of rapid ongoing evolutionary change associated with relaxed selection (l

63 teractions between bacterial cells can drive evolutionary change at the population level, but signifi

64 that directly links regulatory mutations to evolutionary change at the species level.

65 Therefore, evolutionary changes at amino acid position 217 in the H

66 ing, and provides avenues to dissect broader evolutionary changes at FLC.

67 hermobifida fusca, we were able to show that evolutionary changes balance ATP energetic consideration

68 yptic evolution has been defined as adaptive evolutionary change being masked by concurrent environme

69 during both epizootics but found negligible evolutionary change between them.

70 larity revealed here may be important in the evolutionary changes between species and for different i

71 an-altered habitats and is a known driver of evolutionary change, but evidence and understanding of t

72 This evolutionary change can be startlingly rapid, making wee

73 biologists have increasingly recognized that evolutionary change can occur rapidly when natural selec

74 Theory suggests evolutionary change can significantly influence and act

75 operative behaviors, thus demonstrating that evolutionary changes can have profound implications for

76 This evolutionary change causes different species to produce

77 was a time of fundamental environmental and evolutionary change, culminating in the first appearance

78 daptation and, consequently, the dynamics of evolutionary change differed qualitatively among scenari

79 of the ratio of nonsynonymous to synonymous evolutionary changes (dN/dS ratio) located a region of o

80 red as ratios of nonsynonymous to synonymous evolutionary changes [dN/dS ratios]) acting on individua

81 enetic divergence and test for signatures of evolutionary change driven by long-term simulated climat

82 a vertebrate population provides evidence of evolutionary change due to selective pressure at a singl

83 Evolutionary change during infection is often interprete

84 ese patterns exemplify the complex nature of evolutionary changes during dog domestication: the crani

85 Surprisingly, the major locus of evolutionary change for KChIP2 gene expression in heart

86 in understanding the consequences of ongoing evolutionary change for populations, communities and eco

87 linking urban development patterns to rapid evolutionary changes for species that play important fun

88 r fitness may yield erroneous projections of evolutionary change, for example if there is little or n

89 Heckmann et al. simulate likely sequences of evolutionary changes from C3 to C4 photosynthesis bioche

90 e been put forward attempting to explain the evolutionary changes from monkeys to humans that potenti

91 The evolutionary changes had significant repercussions for t

92 demonstrate that both subtle and significant evolutionary change has occurred within antibody epitope

93 sponses to a common environmental driver for evolutionary change has profound consequences for unders

94 s resulting from scenarios where substantial evolutionary change has taken place in a small number of

95 Unexpectedly, substantial evolutionary changes have occurred in giraffe and okapi

96 buffer global change effects through marked evolutionary changes, highlighting the importance of fac

97 These evolutionary changes impact nearly all members of the hn

98 The revealed evolutionary changes imply unrealized risks present in g

99 Phenotypic plasticity can influence evolutionary change in a lineage, ranging from facilitat

100 tudies reveal that the tempo and patterns of evolutionary change in a mammalian gut commensal can be

101 Here, we show that evolutionary change in a region of the brain devoted to

102 the most complete descriptions of short-term evolutionary change in allele frequencies in a natural p

103 Evolutionary change in animal morphology results from al

104 How much evolutionary change in development do we expect?

105 the regulatory genome, causal explanation of evolutionary change in developmental process must be con

106 species are active, explains rapid bursts of evolutionary change in eye shape.

107 Evolutionary change in gene expression is generally cons

108 A major mechanism of evolutionary change in GRN structure is alteration of ci

109 he beta(A)-globin gene has contributed to an evolutionary change in hemoglobin (Hb) function in high-

110 Evolutionary change in individual species has been hypot

111 tifying predictable, directional patterns of evolutionary change in island birds, however, has proved

112 However, Fisher emphasized that evolutionary change in itself is likely to be an importa

113 in shaping complex adaptations that require evolutionary change in multiple genes.

114 e assessment of the anthropogenic impacts on evolutionary change in natural populations, we need long

115 Humans cause widespread evolutionary change in nature, but we still know little

116 drives rapid genotypic change, and (ii) this evolutionary change in one competitor, while not changin

117 crobes are rarely investigated as drivers of evolutionary change in plants.

118 A new model for such degeneration involves evolutionary change in regulatory sequences.

119 Our study provides the first evidence for evolutionary change in sensorimotor integration related

120 The anatomical and physiological basis of evolutionary change in sensory processing at cellular an

121 increase in studies attempting to understand evolutionary change in such populations.

122 r new biogeographic frameworks to understand evolutionary change in the Anthropocene.

123 for the pattern and timing of ecological and evolutionary change in the fossil record.

124 However, the role of evolutionary change in the pathogen during the progressi

125 ed" yeast ribosomes for ES9S reveals that an evolutionary change in the sequence of ES9S endows speci

126 refore, we have identified a gene underlying evolutionary change in the size of a male genital organ,

127 in plasticity when evaluating the drivers of evolutionary change in the wild.

128 he detrimental effects of warming is through evolutionary change in thermal physiology.

129 ittle phenotypic plasticity or potential for evolutionary change in tolerance to high temperature.

130 s to consider social dynamics shown to drive evolutionary change in vitro.

131 proach represents a useful tool for tracking evolutionary change in wild and domesticated genetic res

132 s remarkable adaptive radiation is linked to evolutionary changes in a key reproductive trait regulat

133 ry expression analysis reveal intra-regional evolutionary changes in a multi-regional neural circuit

134 We propose a model of evolutionary changes in Act1-mediated signalling, which

135 gulator of skeletogenesis in echinoderms and evolutionary changes in Alx1 sequence and expression hav

136 tomy, development, and genomics suggest that evolutionary changes in AP patterning establish ecologic

137 ransgenic overexpression of GDF6 phenocopies evolutionary changes in armor-plate size.

138 Bone histological evidence reveals (1) evolutionary changes in bone microstructure in ribs and

139 Evolutionary changes in both host and pathogen lead to a

140 Results indicate that evolutionary changes in brain and neurocranial structure

141 ween two closely related species result from evolutionary changes in brain development.

142 from butchering processes could have fueled evolutionary changes in brain size.

143 ul tool for identifying the genetic basis of evolutionary changes in Canidae.

144 divergent song types and localized relevant evolutionary changes in circuit function downstream of t

145 Our results show how evolutionary changes in cis as well as trans acting sign

146 thin species at the same time scale, leaving evolutionary changes in communities despite recovery at

147 To identify evolutionary changes in connectivity patterns, we quanti

148 Evolutionary changes in CorTFL1 and CorAP1 expression co

149 lation profiling method that allows tracking evolutionary changes in ctDNA at single-molecule resolut

150 appreciation for the relative importance of evolutionary changes in different regulatory genetic and

151 Several lines of evidence suggest that evolutionary changes in dopaminergic afferents of the st

152 an important behavioural marker representing evolutionary changes in ecology, cognition, language and

153 affect sexual size dimorphism (SSD) through evolutionary changes in either male size, female size, o

154 ological niches are rare compared to gradual evolutionary changes in existing traits.

155 ploration of intraspecific plasticity versus evolutionary changes in gastropod nervous systems.

156 for identifying, quantifying, and polarizing evolutionary changes in gene expression profiles across

157 Evolutionary changes in gene expression underlie many as

158 en the applicability of this model and probe evolutionary changes in gradient distributions, we adjus

159 fic traits and novel structures results from evolutionary changes in GRNs.

160 t retropositions are associated with greater evolutionary changes in H3K27me3 and gene expression tha

161 s enigma in some detail, identifying several evolutionary changes in hippocampal cytoarchitecture and

162 derstanding trade-offs in host use caused by evolutionary changes in host immune responses and parasi

163 nges in brain connectivity in the context of evolutionary changes in human brain wiring by comparing

164 lectroreception and demonstrate how discrete evolutionary changes in ion channel structure facilitate

165 al models to investigate the consequences of evolutionary changes in language area connectivity and d

166 uggestions that parent-offspring conflict or evolutionary changes in life history might drive placent

167 election, setting the stage for contemporary evolutionary changes in local populations.

168 ing approach to compare the genetic basis of evolutionary changes in male-limited pigmentation in sev

169 ing cochlear development and to interpreting evolutionary changes in mammalian hearing.

170 of natural morphological variation caused by evolutionary changes in miRNA expression.

171 ant Physcomitrella patens in order to assess evolutionary changes in mitochondrial and plastid proteo

172 Our analysis reveals that relatively minor evolutionary changes in morphology and neural control ha

173 ailed the remarkable plasticity and speed of evolutionary changes in multidrug-resistant K. pneumonia

174 es, TrackSig permits pan-cancer insight into evolutionary changes in mutational processes.

175 These sensory signals generate evolutionary changes in neuroanatomy and behavior; howev

176 r approach also suggests mechanisms by which evolutionary changes in odor production rate and constru

177 Evolutionary changes in organismal traits may occur eith

178 putational methods for investigating coupled evolutionary changes in pairs of positions along the ami

179 gain insight into the mechanisms underlying evolutionary changes in pharyngeal arch development, her

180 ver, to what extent elevated CO2 will induce evolutionary changes in photosynthetic organisms is stil

181 Evolutionary changes in placental morphology remain poor

182 lant productivity and impacts ecological and evolutionary changes in plant populations.

183 y a few dominant drivers explain most of the evolutionary changes in population growth rates.

184 oth timing and dependence on Hfq, suggesting evolutionary changes in posttranscriptional regulation b

185 developmental cost hypothesis, we show that evolutionary changes in pre- and postnatal brain growth

186 rsatile and scalable approach to investigate evolutionary changes in protein function and thus can pr

187 f conservation, we detected many non-neutral evolutionary changes in protein-coding genes and noncodi

188 genetic toolkits of deeply conserved genes, evolutionary changes in protein-coding genes, cis regula

189 MA silk evolved ~376 MYA and identifying how evolutionary changes in proteins influenced silk mechani

190 Investigations of evolutionary changes in RNA binding proteins, splice var

191 olved from C3 ancestors, this work links the evolutionary changes in sequence, PPCK expression, and p

192 Evolutionary changes in staging embryogenesis and in mut

193 s, and bioinformatics provides means to link evolutionary changes in structure-dynamics function to t

194 ritiana and Drosophila simulans is caused by evolutionary changes in tartan (trn), which encodes a tr

195 results highlight a significant tolerance to evolutionary changes in TF binding intensity in mammalia

196 Key to cell type identity are evolutionary changes in the 'core regulatory complex' (C

197 We analyzed the molecular evolutionary changes in the attachment (G) glycoprotein

198 s within Florideophyceae were accompanied by evolutionary changes in the carposporophyte stage, leadi

199 , we propose a method that aims at detecting evolutionary changes in the configuration of a complex s

200 rstanding of complex internal morphology and evolutionary changes in the cranium.

201 Our data suggest that evolutionary changes in the expression profile of indivi

202 ynamics and tissue specification result from evolutionary changes in the gene regulatory network that

203 It also explores the evidence for evolutionary changes in the genetic structure of anatomi

204 In theory, a few naturally occurring evolutionary changes in the genome of a model organism m

205 mans can be traced back to developmental and evolutionary changes in the lateral frontoparietal netwo

206 This observation indicates recent evolutionary changes in the osmoprotection strategy of t

207 cular recognition mechanisms associated with evolutionary changes in the pIgR protein.

208 should not be used to make inferences about evolutionary changes in the relative size or reorganizat

209 Heterochrony, that is, evolutionary changes in the relative timing of developme

210 We show that evolutionary changes in the shape of the humerus are dri

211 anding of the genetic and molecular basis of evolutionary changes in the size and proportion of limbs

212 species that are uncovering new evidence for evolutionary changes in the size and the number of neuro

213 in substrate discrimination as reflected in evolutionary changes in the specificity constant (k(cat)

214 llowing not only for better understanding of evolutionary changes in the threatened populations, but

215 ated great apes leaves unresolved when these evolutionary changes in the timing of cortical developme

216 m the same or different generations revealed evolutionary changes in their interaction, including an

217 o the Recent; this allowed us to investigate evolutionary changes in these species in response to cli

218 Evolutionary changes in this gene are hypothesized to ha

219 How do evolutionary changes in this organization affect large-s

220 The work also raises questions about the evolutionary changes in this protein family following th

221 However, we know little about how evolutionary changes in trait distributions over time af

222 Evolutionary changes in traits involved in both ecologic

223 Evolutionary changes in transcription networks are an im

224 channel Nav1.4, were facilitated by ancient evolutionary changes in two other members of the same ge

225 the location of RA synthesis correlate with evolutionary changes in vertebrate dentitions.

226 ommonly acquire a smaller number of putative evolutionary changes, in which nucleotide variants or ge

227 Our findings reveal substantial evolutionary changes including gene amplifications, rear

228 ssure from harvesting, yet the potential for evolutionary change induced by humans has received surpr

229 Symbiosis is a major force of evolutionary change, influencing virtually all aspects o

230 e largely architectural, and it appears that evolutionary change involved changes in protein-protein

231 ested a role in brain evolution; however the evolutionary changes involved have not been investigated

232 Although evolutionary changes involving heteroblasty might contri

233 It is currently not known whether evolutionary change is likely to be able to keep pace wi

234 in an experimental design in which host cell evolutionary change is prevented.

235 on created by mutation, the raw material for evolutionary change, is translated into phenotypes by fl

236 field to better understand the molecular and evolutionary changes leading to pandemic strains.

237 sharing ontogenetic pathways, making certain evolutionary changes less likely.

238 Accounting for evolutionary change may be critical when predicting the

239 Feedbacks between ecological and evolutionary change may play important roles in communit

240 ment, consistent with suggestions that their evolutionary changes may have altered social and/or cogn

241 lity is as high as it has been historically, evolutionary changes may result in economic losses, but

242 Although these evolutionary changes most likely contributed to the orig

243 Importantly, neither the negative evolutionary change, nor the selective pressures that dr

244 terized by profound global environmental and evolutionary changes, not least of which included a majo

245 um DSX binding sites was used to examine the evolutionary changes occurring in DSX and its targets in

246 y Synthesis is needed to reconceptualize how evolutionary change occurs.

247 Antagonistic coevolution--the reciprocal evolutionary change of interacting species--might reconc

248 antibacterial agents because due to the slow evolutionary change of such binding pockets, ligands of

249 specific families of flies, reveals frequent evolutionary changes of body axis determinants and a rem

250 ecialization is crucial to understanding the evolutionary changes of craniofacial biomechanics and th

251 We speculate that evolutionary changes of intramolecular regulation have l

252 In contrast, evolutionary changes of the epigenome and the transcript

253 sive structural comparison to understand the evolutionary changes of the GII.17/13/21 lineage, includ

254 h factors might have contributed to the fast evolutionary changes of this gradient.

255 sitional vertebrae survive to allow eventual evolutionary changes of trunk vertebral numbers.

256 acts on nontarget species, including driving evolutionary change, often with unknown consequences for

257 Although the genomes showed very little evolutionary change on a nucleotide level, we found evid

258 ns between closely related species can drive evolutionary change on observable time scales.

259 their host glycan ligands, as well as their evolutionary changes over time with alterations in their

260 has been a prime example of recapitulation - evolutionary change (phylogeny) mirrored in development

261 Predicting evolutionary change poses numerous challenges.

262 Collectively, these evolutionary changes probably occurred to minimize delet

263 how variation in those mechanisms can drive evolutionary change remain poorly understood.

264 Therefore, the contribution of miRNAs to evolutionary change remains unknown [1, 4].

265 but quantifying the selective forces shaping evolutionary changes remains challenging.

266 d linguistic barriers and can promote faster evolutionary changes shaped by gene-culture interactions

267 It is unclear where in the nervous system evolutionary changes tend to occur.

268 ed that TFC number regulation is a target of evolutionary change that affects ovariole number.

269 These traits could all result from an evolutionary change that enhanced radial migration of NS

270 in an ultrasocial manner without the radical evolutionary changes that are experienced by other speci

271 ffer unique opportunities to reconstruct the evolutionary changes that decouple male and female trait

272 dentity might therefore uncover the steps of evolutionary changes that eventually resulted in modific

273 systems for interrogating the types of deep evolutionary changes that have restructured developmenta

274 ting in the community, but we found multiple evolutionary changes that in combination over time incre

275 a major challenge is to detect genomic-level evolutionary changes that increase microbial virulence.

276 Here, we demonstrate how the evolutionary changes that led to the emergence of SRGAP2

277 The evolutionary changes that led to the muscular anatomy of

278 ronmental change is expected to generate eco-evolutionary change, that changes in the average environ

279 s once provided the main data for studies of evolutionary change, the mechanisms shaping phenotypic d

280 The most widely accepted model of evolutionary change, the Modern Evolutionary Synthesis,

281 genome duplication is thought to facilitate evolutionary change through sub- and neo-functionalizati

282 ciple whereby protein oligomerization allows evolutionary change to accumulate away from a conserved

283 These results suggest that evolutionary changes to neocortical development promotin

284 Here, we examine evolutionary changes to the sequence and structure of sp

285 been proposed to initiate and bias adaptive evolutionary change toward particular directions.

286 We find that evolutionary changes toward faster growth and earlier ma

287 dge, no study has yet reported evidence that evolutionary change underlies the most widely reported p

288 equence provides important insights into the evolutionary changes underlying host specialization.

289 ity and circuitry of nervous systems undergo evolutionary change, we lack understanding of the genera

290 understand the physical constraints on these evolutionary changes, we reconstructed in silico ancestr

291 understand the molecular bases behind these evolutionary changes, we solved the crystal structures o

292 paradox" highlights our inability to predict evolutionary change, which is especially concerning with

293 predicts that directional selection leads to evolutionary change while depleting standing genetic var

294 netic heterogeneity is the result of ongoing evolutionary change within each cancer.

295 ution, and is likely to be a major driver of evolutionary change within species.

296 By extracting correlated evolutionary changes within 700+ sequences, we built a m

297 While several traits have been resolved to evolutionary changes within a single gene, the evolution

298 MAT has undergone significant evolutionary changes within the Cryptococcus genus, incl

299 This EE strategy may reflect evolutionary changes within the holometabolous insects a

300 sons to mobilize and modify genomes, driving evolutionary change without substantially affecting repr