ライフサイエンスコーパス: evolutionary distance

1 d a decline in recombination with increasing evolutionary distance.

2 isiae was tested and found to correlate with evolutionary distance.

3 ecology of the strains in addition to their evolutionary distance.

4 ling for each additional 10 million years of evolutionary distance.

5 a major obstacle for estimating indel-based evolutionary distance.

6 alignments of long genomic sequences at any evolutionary distance.

7 patterns of expression--changes unrelated to evolutionary distance.

8 me-wide multi-species exon homologies at any evolutionary distance.

9 e their distinct anatomies, life cycles, and evolutionary distance.

10 riptomic variation across species related to evolutionary distance.

11 nd little across organs, and simply reflects evolutionary distance.

12 etween these genomes, independently of their evolutionary distance.

13 by ET-MIp and best discerned within a short evolutionary distance.

14 sion depends on gene function, cell type and evolutionary distance.

15 ns, quality of the training data set and the evolutionary distance.

16 n via blastocyst complementation across wide evolutionary distances.

17 distance between the plants, even to ancient evolutionary distances.

18 zation decisions to be based on contemporary evolutionary distances.

19 grammed cell death are conserved across wide evolutionary distances.

20 ips between sequence similarity E-values and evolutionary distances.

21 ing maximum likelihood estimates of pairwise evolutionary distances.

22 imilarly for chicken-human and chicken-mouse evolutionary distances.

23 g their performance over both short and long evolutionary distances.

24 changeable between plants separated by large evolutionary distances.

25 sterious yet general phenomenon across great evolutionary distances.

26 osome segregation are conserved across large evolutionary distances.

27 assembly properties are conserved over large evolutionary distances.

28 sequence conservation, especially at larger evolutionary distances.

29 on landscapes are conserved over significant evolutionary distances.

30 nd together on the same chromosome over vast evolutionary distances.

31 e sequence comparison and annotation at long evolutionary distances.

32 or traits that appear divergent across large evolutionary distances.

33 overt sequence homologies and over extensive evolutionary distances.

34 a broad range of phylogenetic topologies and evolutionary distances.

35 and ancestral reconstruction to bridge large evolutionary distances.

36 plant genomes, even across relatively short evolutionary distances.

37 tion regulator can be conserved across large evolutionary distances.

38 pared in vivo binding data across a range of evolutionary distances.

39 servation of similar body plans across large evolutionary distances.

40 ast, and our findings may apply across large evolutionary distances.

41 are also likely to be conserved across large evolutionary distances.

42 NA/target interaction maintained across long evolutionary distances?

43 ls to birds and mammals despite considerable evolutionary distance [1, 2].

44 Our results suggest that evolutionary distance alone is not a precise predictor o

45 Evolutionary distances among different amino acid sequen

46 expresses >80 different R2R3 Myb genes, and evolutionary distances among maize Myb(BRH) sequences in

47 The calculation of evolutionary distances among proteins and distances at t

48 nding the pool of LDOs while maintaining low evolutionary distance and a high level of functional rel

49 f this region, with similarities that mirror evolutionary distance and are consistent between the tra

50 Despite the large evolutionary distance and differences in root radial pat

51 Despite the large evolutionary distance and extensive rewiring of individu

52 king conservation over >400 million years of evolutionary distance and frequently are located megabas

53 Thus, despite their evolutionary distance and limited sequence identity, bot

54 variation in enzyme concentration is due to evolutionary distance and may be nonadaptive.

55 transposon function over a relatively large evolutionary distance and suggests that the piggyBac sys

56 ls of nucleotide substitution for estimating evolutionary distances and hint at bright prospects for

57 es increased taxon sampling to overcome long evolutionary distances and identify putative hidden orth

58 otein sequences that are conserved over long evolutionary distances and thus are critically important

59 , binding divergence increased linearly with evolutionary distance, and CTCF binding profiles are div

60 ol genes maintain their diagonality at large evolutionary distance, and peak at the onset of gastrula

61 by genes that have been conserved over vast evolutionary distances, and most organisms are able to f

62 allow comparisons between species at various evolutionary distances, and powerful splice signal model

63 ct 44 Sarbecovirus genomes at ideally-suited evolutionary distances, and quantify protein-coding evol

64 titution rates, computations of the error of evolutionary distances, and simulations of molecular evo

65 ogous noncoding DNA for organisms a suitable evolutionary distance apart is a powerful tool for the i

66 in the study of molecular evolution because evolutionary distances are required for estimating the r

67 In spite of the evolutionary distance between algae and mammals, C. rein

68 leles were common and increased with greater evolutionary distance between allele group members.

69 ging flower morphologies and the substantial evolutionary distance between Arabidopsis and maize, our

70 m in retinylidene proteins spanning the vast evolutionary distance between archaea and humans.

71 For example, the evolutionary distance between chicken and human provides

72 erved in other baculoviruses suggest a large evolutionary distance between CuniNPV and lepidopteran b

73 e also developed a new method to measure the evolutionary distance between different cancers based on

74 We propose a method for estimating the evolutionary distance between DNA sequences in terms of

75 Here, we investigated the impact of the evolutionary distance between donor and recipient specie

76 and 3D structural divergence correlates with evolutionary distance between genomes.

77 (CCV) was utilized to calculate the pairwise evolutionary distance between genotypes.

78 20 to 59%), perhaps reflecting a significant evolutionary distance between lepidopteran and orthopter

79 Despite the evolutionary distance between M. smegmatis and M. tuberc

80 Given the evolutionary distance between parrots and primates, the

81 ily, superfamily, and fold) depending on the evolutionary distance between protein sequences.

82 Given the evolutionary distance between protozoans and vertebrates

83 edium lengths, our method recovers the known evolutionary distance between rat and mouse, 0.014 indel

84 The vast evolutionary distance between the parasite and the host

85 ts human ortholog does not increase with the evolutionary distance between the proteins, indicating t

86 Despite the substantial evolutionary distance between the species analyzed, we i

87 Given sufficient evolutionary distance between the two sequences, we achi

88 ative replicases despite >1 billion years of evolutionary distance between them.

89 s between these enzymes highlights the large evolutionary distance between them.

90 divergent species suggests that substantial evolutionary distance between these two species has not

91 history and traits is challenging due to the evolutionary distance between tropical and temperate ass

92 However, the vast evolutionary distance between trypanosomes and the highe

93 Despite the evolutionary distance between vertebrates and microbial

94 knowledge of gene function across the large evolutionary distances between Arabidopsis and diverse c

95 Despite the large evolutionary distances between metazoan species, they ca

96 logenetic reconstruction and analysis of the evolutionary distances between NDV-Peru/08 and other iso

97 use conservation, its scores correlated with evolutionary distances between orthologs in cross-specie

98 This matrix can then be used to calculate evolutionary distances between pairs of sequences in the

99 n a multiple sequence alignment, we estimate evolutionary distances between proteins measured in expe

100 However, a recent survey of evolutionary distances between Saccharomyces cerevisiae

101 asing of major and minor alleles, as well as evolutionary distances between samples, and are able to

102 oduce genome conservation--a novel metric of evolutionary distances between species that simultaneous

103 However, its utility largely depends on the evolutionary distances between the species involved.

104 species is in accordance with the estimated evolutionary distances between them and we find it to ap

105 Finally, distinctive features and evolutionary distances between these different viral sub

106 The evolutionary distances between these four groups were al

107 ined a network-based clustering method using evolutionary distances between viral sequences with stat

108 Despite their evolutionary distance, both proteins fold in a strict N-

109 on gene orthology and paralogy across broad evolutionary distances, both of fundamental value and se

110 found that many tools worked well at shorter evolutionary distances, but fewer performed competitivel

111 stem are orthologously conserved across long evolutionary distances, but genes in these pathways evol

112 p, we find the best fit approximation of the evolutionary distances by Euclidian distances and thus r

113 , a new alignment-free method that estimates evolutionary distances by measuring the decay of exact s

114 undance data with genome-derived measures of evolutionary distance can provide a clear indication of

115 s sequence alignments with good estimates of evolutionary distances can be a valuable resource for mo

116 prokaryote genomes spanning a wide range of evolutionary distances changed the conceptual foundation

117 orthologous groups, sequence identities, and evolutionary distances considering several MsV isolates.

118 ns in prokaryotes and eukaryotes revealed an evolutionary distance consistent with that inferred from

119 orithm for automated classification based on evolutionary distance data was written in S.

120 ect interspecies chimera generation, such as evolutionary distance, developmental timing, and apoptos

121 que method, RED, that utilizes the ratios of evolutionary distances E(d) to distinguish between alter

122 nized in C. elegans, implying that over this evolutionary distance enough changes occurred in cis-reg

123 simplifies the exploration of its impact on evolutionary distance errors and relative-rate tests.

124 ALFRED-G is an alignment-free heuristic for evolutionary distance estimation between two biological

125 nce alignment, substitution model selection, evolutionary distance estimation, phylogeny inference, s

126 atory regions can retain function over large evolutionary distances, even though the DNA sequences ar

127 transferase activity is conserved over large evolutionary distance for these proteins.

128 increasingly used and relied on to determine evolutionary distances for the basis of rational hierarc

129 hylogenetic trees shows that branch lengths (evolutionary distances) for third codon positions in CG-

130 cated host species, we show that the average evolutionary distance from an infected host to other mam

131 ria gruberi is a unicellular eukaryote whose evolutionary distance from animals and fungi has made it

132 consensus sequences, suggesting substantial evolutionary distance from known avian strain sequences.

133 nymous differences than expected, suggesting evolutionary distance from known avian strains.

134 lipoproteins; however, due in part to their evolutionary distance from more well-studied bacteria, s

135 zebrafish are of particular interest as the evolutionary distance from non-ichthyic homologues is la

136 -to-guaiacyl ratio increased with the enzyme evolutionary distance from the first peroxidase ancestor

137 ot clear whether the mouse is at the correct evolutionary distance from the human to provide sufficie

138 se mRNAs often 'disappeared' with increasing evolutionary distance from the parental species.

139 ilies, even when from an organism at a great evolutionary distance from those in the analysis.

140 substitution matrices over a range of target evolutionary distances from 20 to 200 Point Accepted Mut

141 This yields more realistic estimates of evolutionary distances from amino-acid sequences, which

142 to each other than are genomes at equivalent evolutionary distances from non-gut environments, sugges

143 Despite the evolutionary distance, functional parallels exist betwee

144 Our analysis suggests that, at long evolutionary distances, gene essentiality is significant

145 f both butterflies and primates, spanning an evolutionary distance >500 million years.

146 Estimation of evolutionary distances has always been a major issue in

147 amete-specific protein conserved across vast evolutionary distances, has garnered considerable attent

148 f aging rate that are conserved over a broad evolutionary distance have now been identified.

149 Over long evolutionary distances, however, sequence-based methods

150 four cDNA-to-genome comparisons at different evolutionary distances (human-dog, human-mouse, human-ch

151 ), phylogenies contain information about the evolutionary distances (i.e. branch lengths) between all

152 e, yet many are highly conserved across vast evolutionary distances, implying strong selection on the

153 physiological characteristics, and also the evolutionary distance in genome structure.

154 rgence by a factor of 4, so that mouse-human evolutionary distance in terms of selectively neutral in

155 t than nucleotide substitutions, mouse-human evolutionary distance in terms of selectively neutral su

156 the transcriptional machinery across a large evolutionary distance in the regulation of small nuclear

157 to accommodate consistently a wide range of evolutionary distances in a comparison framework based u

158 Analysis of sequence substitutions and evolutionary distances in this data set revealed that mo

159 it performs robustly across a large span of evolutionary distances, including across the closely rel

160 Moreover, as host evolutionary distance increases, reassortment is increas

161 ces, important calibration points to convert evolutionary distance into time, are lacking, however; Z

162 Evolutionary distance is traditionally modeled using glo

163 The matrix of evolutionary distances is a model-based statistic, deriv

164 A sequences from multiple species at varying evolutionary distances is a powerful approach for identi

165 on of orthologs (gene families) across wider evolutionary distances is important for understanding th

166 ined with conserved genomic synteny at large evolutionary distances, makes the dcw gene cluster a rob

167 e form of interactive phylogenetic trees and evolutionary distance matrices.

168 nism of action); Types (that largely reflect evolutionary distance measured by sequence similarity);

169 closely related by MiSeq, within one yearly evolutionary distance of <=5 single nucleotide polymorph

170 o distantly related teleosts separated by an evolutionary distance of 115-200 Myr.

171 have been conserved from fish to mammals, an evolutionary distance of 450 million years.

172 served a significant correlation between the evolutionary distance of Malus species and their microbi

173 Despite the evolutionary distance of paramyxovirus F proteins, their

174 The evolutionary distance of the 1918 NP sequences from avia

175 n-defined supraclonal sets, we exploited the evolutionary distance of the chicken immune system and t

176 penalties behave as a function of the target evolutionary distance of the substitution matrix.

177 This analysis also allows measurement of evolutionary distances of different proteins.

178 It has been observed that the evolutionary distances of interacting proteins often dis

179 litates unbiased assessment of the impact of evolutionary distance on predictive power.

180 ise provides the greatest accuracy at higher evolutionary distances, out-performing both AlignFS and

181 he number of core genes, calculated pairwise evolutionary distances (p-distances) based on nucleotide

182 sal of amino acid replacements and, at short evolutionary distances, pervasive homoplasy.

183 od was developed that utilizes the ratios of evolutionary distances (RED) to distinguish between alte

184 tion of intron splicing signals across large evolutionary distances, reveal unexpected motif conserva

185 are present at orthologous genes across vast evolutionary distances, revealing a surprising level of

186 is and rice (Oryza sativa) despite the large evolutionary distance separating these plants.

187 This ambiguity is partly due to the long evolutionary distances separating animal and bacterial p

188 tested on vertebrate comparisons at diverse evolutionary distances, sim4cc had significantly higher

189 hat of the human GRK2 gene, highlighting the evolutionary distance since the divergence of these two

190 From parsimonious calculations of evolutionary distances since speciation, ctt-11, ctt-12,

191 ot be neglected in calculations that rely on evolutionary distances, such as the confidence intervals

192 related organisms, variation across broader evolutionary distances suggests that only a few residues

193 Conservation across such evolutionary distances suggests that soyuz1 plays a cruc

194 on of intron-exon structure, even over large evolutionary distances, suggests that comparative method

195 on the specific target for evolution and the evolutionary distance that needs to be crossed.

196 Despite the considerable evolutionary distance that separates ubiquitin from GlUb

197 Because of the great evolutionary distance that separates vertebrates from ce

198 relatively sparse sampling across the broad evolutionary distances that exist, which has limited our

199 ssive repository of orthologs and associated evolutionary distances that was built using the reciproc

200 nged so extensively (and over a much smaller evolutionary distance) that its cis-regulatory sequence

201 With increasing evolutionary distance the interspecies correlations in g

202 Despite this evolutionary distance, the genomes of these two species

203 Despite their evolutionary distance, the Saccharomyces cerevisiae retr

204 These results indicate that at these evolutionary distances, the contribution of indels to se

205 results on correcting the estimation bias of evolutionary distances, the estimation of the pattern of

206 It is found that, despite their evolutionary distance, these eubacterial and vertebrate

207 Despite their evolutionary distance, these proteins share structural a

208 onservation of cell cycle genes across large evolutionary distances, this approach identified context

209 ance of the gene recognition system with the evolutionary distance (time) between the two genomes.

210 lation, development and human disease, whose evolutionary distance to all other currently sequenced f

211 between the number of interactions and their evolutionary distance to its orthologs in other organism

212 svirus (KSHV) gB sequences and had a shorter evolutionary distance to KSHV gB sequences than to any o

213 olate-based strategies, as they minimize the evolutionary distances to circulating strains.

214 ignment and maximum likelihood estimation of evolutionary distances to detect orthologs between two g

215 ET uses evolutionary distances to estimate functional distances

216 inds protein similarities across significant evolutionary distances using sensitive protein domain pr

217 Despite their evolutionary distance, wasps and vertebrates share simil

218 eotide difference, amino acid difference and evolutionary distance, we constructed viral networks and

219 of disulfide bonds, and that spanned various evolutionary distances, were aligned.

220 Phylo SI is particularly efficient on short evolutionary distances where synteny footprints remain d

221 functional module can be conserved at great evolutionary distances, whereas the associated regulator

222 idue in a gap (q+r) changes as a function of evolutionary distance, while the gap extension penalty f

223 ven manage to compete favourably for general evolutionary distances with an alignment produced by Gen

224 O enrichment analysis tool that incorporates evolutionary distances with species-level enrichment res

225 based on maximum likelihood estimates of the evolutionary distances, with branch lengths then calcula

226 le, novel CYP families may reflect the large evolutionary distance within the cnidarians, unique phys

227 rochlorococcus strains that span the largest evolutionary distance within the Prochlorococcus lineage

228 However, based on synonymous evolutionary distances, X-linked genes in M. musculus fa