ライフサイエンスコーパス: excess risk of

1 CI], 6.7 to 9.6) increased risk of a PTM, an excess risk of 102.7 cases/10,000 persons/yr (age and se

2 antly affected by CEE, there was an absolute excess risk of 12 additional strokes per 10 000 person-y

3 ines was 1.43 (95% CI 0.88 to 2.34), with an excess risk of 27.80 per million doses (-21.88 to 77.48)

4 h well-done/very well-done red meat, with an excess risk of 29% per 10 g/day (OR, 1.29; CI, 1.08-1.54

5 with an SIR of 1.28 (95% CI, 1.19-1.38) and excess risk of 57.25 per 10 000 person-years.

6 s 22.9 (95% CI, 14.2 to 35) with an absolute excess risk of 93.7 cases per 10,000 person-years.

7 who received >or= 270 mg/m(2) had a 4.5-fold excess risk of abnormal NICT (95% CI, 2.1 to 9.6) compar

8 exposure of the heart to radiation to avoid excess risk of ACEs after radiotherapy for BC.

9 Gouty arthritis is associated with an excess risk of acute MI, and this is not explained by it

10 Conclusion The excess risk of acute myeloid leukemia and/or myelodyspla

11 tertile was associated with an even greater excess risk of advanced fibrosis than advanced inflammat

12 imal to no effects on blood pressure, and no excess risk of adverse kidney events.

13 It remains disputed whether women are at excess risk of adverse outcomes versus men after non-ST-

14 The excess risk of AF associated with obesity appears to be

15 and hospital admission during follow-up, the excess risk of AIDS-related death decreased for heterose

16 erial administration was not associated with excess risk of AKI acute kidney injury , dialysis, or de

17 oth MyCode and UKBB, there was a significant excess risk of all cancers (odds ratio [OR], 1.33 [95% C

18 Ethnic minorities were also at excess risk of all psychotic disorders (1.75 [1.53-2.00]

19 Point estimates of the HRs indicate that excess risk of all stroke was apparent in all age groups

20 In SEER 9, there was a significant excess risk of all types of second cancers combined (SIR

21 The excess risk of all-cause and cardiopulmonary mortality f

22 As a primary contributor to the excess risk of all-cause and cardiovascular death in dia

23 h type 1 diabetes have a roughly 40% greater excess risk of all-cause mortality, and twice the excess

24 viduals not using insulin, the authors found excess risk of all-cause, cardiovascular, and coronary h

25 Previous studies have shown an excess risk of Alzheimer's disease and related dementias

26 Recently, an excess risk of AML/MDS was found among 5652 patients wit

27 compared with the general population had an excess risk of anal cancer, with SIRs of 109.8 (95% CI,

28 of anemia); the adjusted odds ratios showing excess risk of anemia associated with demographic factor

29 The excess risk of antibiotic use and hospital-treated infec

30 ssel and cardioembolic subtypes, they had no excess risk of asymptomatic carotid disease (adjusted OR

31 The excess risk of atrial fibrillation in individuals with t

32 Among individuals with normoalbuminuria, no excess risk of atrial fibrillation was noted in men with

33 rofound B-cell deficiency associated with an excess risk of bacterial infection and higher mortality.

34 primary school were associated with a modest excess risk of becoming tobacco-dependent by young adult

35 ds assessed at YAT0) signaled a 2- to 3-fold excess risk of being drug-dependent (adjusted prevalence

36 Absolute excess risk of biliary tract disease associated with ADP

37 ducation received also seemed to explain the excess risk of black race in the discrepant group that r

38 xposure is unlikely to explain a substantial excess risk of bladder cancer.

39 No excess risks of bleeding or other serious adverse events

40 Significant excess risks of both outcomes were observed in obese wom

41 The excess risk of breast cancer among Jewish women has been

42 Our findings suggest that the excess risk of breast cancer associated with alcohol con

43 There was no excess risk of breast cancer associated with induced abo

44 ation-scale cohorts, there was a significant excess risk of breast, prostate, kidney, bladder, and ly

45 was heterogeneity with one study showing an excess risk of campylobacteriosis.

46 pients should balance the harms, such as the excess risk of cancer against the survival gains and qua

47 Virtually all the excess risk of cancer among first-degree relatives of ch

48 risk factors, we converted absorbed doses to excess risk of cancer incidence and used them to directl

49 ll, survivors have a clear radiation-related excess risk of cancer, and people exposed as children ha

50 Specifically, we observed significant excess risks of cancers of the endometrium (n = 11; obse

51 on analysis of SIRs was used to estimate the excess risk of cardiac interventions from mediastinal ir

52 tandard incidence ratios (SIRs) and absolute excess risks of cardiac procedures compared with a norma

53 The excess risk of cardiometabolic events was even higher wh

54 However, the adjusted excess risk of cardiometabolic events was significantly

55 s has been shown to unequivocally reduce the excess risk of cardiovascular complications.

56 Cancer survivors might have an excess risk of cardiovascular disease (CVD) resulting fr

57 ents with chronic kidney disease, experience excess risk of cardiovascular disease and elevated total

58 The excess risk of cardiovascular disease associated with a

59 Excess risk of cardiovascular disease occurs in effectiv

60 associated with heightened inflammation and excess risk of cardiovascular disease, cancer and other

61 Diabetes confers a two times excess risk of cardiovascular disease, yet predicting in

62 th systemic lupus erythematosus (SLE) are at excess risk of cardiovascular events (CVEs).

63 HIV-infected adults have excess risk of cardiovascular, liver, kidney, bone, and

64 95% CI: 1.0, 1.4) were associated with small excess risks of cardiovascular disease; periodontal dise

65 The 10-year absolute excess risks of CD and UC were 0.9 (95% CI 0.7-1.1) and

66 rs864537A > G, in CD247 (AA genotype) had an excess risk of celiac autoimmunity when born March-Augus

67 The excess risk of cerebral infarction among CNS tumor survi

68 risk women with previous negative tests, the excess risk of cervical cancer associated with less freq

69 nicolaou tests is associated with an average excess risk of cervical cancer of approximately 3 in 100

70 approximately 0.08 U) associated with a 48% excess risk of CHD (odds ratio [OR] for CHD, 1.48; 95% c

71 oprotein cholesterol were associated with an excess risk of CHD among women who received hormone ther

72 lity, substantial absolute risk and absolute excess risk of CHD and CVD death for younger men with el

73 ational studies suggest an approximately 40% excess risk of CHD in employees working long hours.

74 e coronary heart disease (CHD) have a marked excess risk of CHD risk factors and premature CHD.

75 RA conferred a significant excess risk of CHF (hazard ratio [HR] 1.87, 95% CI 1.47-

76 Eliminating the excess risk of CHF in patients with RA could significant

77 The excess risk of chronic cough seen with occupational fume

78 The excess risk of chronic GVHD was explained by differences

79 Although the excess risk of CKD among African Americans was much grea

80 ive risk (RR) to 2.49, explaining 12% of the excess risk of CKD among African Americans.

81 Nearly one-half of the excess risk of CKD among African-American adults can be

82 fiable factors would account for much of the excess risk of CKD.

83 ndings provide mechanistic insights into the excess risk of clinical CAD among diabetic individuals,

84 butions of different neuropathologies to the excess risk of cognitive decline in diabetes mellitus (D

85 This excess risk of cognitive impairment among continuous smo

86 TYH defects impart a 93-fold (95% CI 42-213) excess risk of colorectal cancer, which accounts for 0.8

87 Excess risk of concomitant use of nsNSAIDs with anticoag

88 se of 0.72 Gy, the 20-year radiation-related excess risk of contralateral breast cancer was estimated

89 The absolute excess risk of contralateral breast cancer was greater i

90 Whether smoking confers the same excess risk of coronary heart disease for women as it do

91 WH to inform surveillance efforts and 2) any excess risk of COVID-19 among PLWH due to biological eff

92 hildhood immunisation in Africa outweigh the excess risk of COVID-19 deaths associated with vaccinati

93 The excess risk of CVD associated with active smoking was ex

94 An excess risk of CVD occurs early in the RA disease course

95 Compared with whites, blacks had an overall excess risk of death (HR, 1.16; 95% confidence interval

96 was significantly associated with increased excess risk of death (RER 1.48, 95% CI 1.31-1.68, p-valu

97 national health expenditure on the relative excess risk of death (RER).

98 y-based observational study to determine the excess risk of death according to the level of glycemic

99 People who use illicit opioids have excess risk of death across all major causes of death we

100 th stages I to IIA disease had no noteworthy excess risk of death after they reached EFS24, whereas r

101 hing by insurance explained one third of the excess risk of death among nonelderly black versus white

102 Long-term trends in excess risk of death and cardiovascular outcomes have no

103 d optimal levels for risk factors related to excess risk of death and cardiovascular outcomes in type

104 with post-orchiectomy XRT are at significant excess risk of death as a result of cardiac disease or s

105 The excess risk of death associated with a high BMI, however

106 HR: 0.96; 95% CI: 0.58 to 1.53), whereas the excess risk of death associated with HG aortic stenosis

107 mer smokers have about only a quarter of the excess risk of death compared to current smokers.

108 Our study found an excess risk of death due to both liver-specific and non-

109 tients with CK-MB elevation after PCI are at excess risk of death for 3 to 4 months, although prolong

110 The excess risk of death from any cause and of death from ca

111 The excess risk of death from ischemic, but not hemorrhagic,

112 stics matching accounted for the 54% and 27% excess risk of death in black patients, respectively.

113 rs combined accounted for 76.3% of the total excess risk of death in black patients; insurance accoun

114 The excess risk of death in black versus white men diagnosed

115 In those age >/= 65 years, the excess risk of death in blacks versus whites was nonsign

116 aprotinin was found to be associated with an excess risk of death of 1.59 per 100 patients (95% CI, 0

117 Excess risk of death was confined to the highest quintil

118 pared to matched controls, and over half the excess risk of death was due to seemingly unrelated co-m

119 However, whether the excess risk of death with graft function (DWGF) differs

120 Because of the excess risk of death, concurrent or anticipated use of c

121 Atrial fibrillation carries an excess risk of death, which is the highest for AF develo

122 est that inflammation may play a part in the excess risk of death.

123 The excess risks of death from any cause and cardiovascular

124 The excess risks of death from any cause and death from card

125 ne third of all deaths; the largest absolute excess risks of death were from renal disease (rate rati

126 AKI) has been reported to be associated with excess risks of death, kidney disease progression and ca

127 least (<0.25 mile/d) experienced a 1.8-fold excess risk of dementia compared with those who walked m

128 with men who walked the most (>2 mile/d), an excess risk of dementia was also observed in those who w

129 rated that statin therapy is associated with excess risk of developing diabetes mellitus.

130 abetes during 2006 and 2007, we measured the excess risk of developing diabetes triggered by undernou

131 rol alone was associated with a 2- to 3-fold excess risk of developing drug dependence (adjusted rela

132 ) up to the age of 4 years are at a 150-fold excess risk of developing myeloid leukemia (ML-DS).

133 icans and Hispanics have a two- to threefold excess risk of developing NIDDM compared with non-Hispan

134 tients with metabolic syndrome were at a 21% excess risk of developing subclinical hypothyroidism (ad

135 Survivors of childhood cancer are at excess risk of developing subsequent primary neoplasms b

136 rum potassium appeared to explain 18% of the excess risk of diabetes in African Americans, which is c

137 that low serum potassium contributes to the excess risk of diabetes in African Americans.

138 We found a massive excess risk of diabetes in people born during the times

139 eded statin therapy may be withheld to avoid excess risk of diabetes while representing the strongest

140 In contrast, a modest excess risk of disability was observed in African Caribb

141 An excess risk of DLBCL and FL was found in Q fever patient

142 butions of different neuropathologies to the excess risk of DM are needed.

143 Given the lack of sex differences in the excess risk of DWGF (other than in prepubertal recipient

144 al patient data meta-analysis to compare the excess risk of DWGF between male and female recipients o

145 cipients aged 0 to 12 y experienced a higher excess risk of DWGF than male recipients (relative exces

146 The excess risk of each cause of death in the 5 years subseq

147 % CI: 1.06-3.83) higher risk than the sum of excess risk of each factor.

148 an elevated burden of chronic disease and an excess risk of early death compared with the general pop

149 al died during the first week after PCI, and excess risk of early death for patients with CK-MB eleva

150 aortic aneurysm (rAAA) were associated with excess risk of early mortality in women.

151 g in-hospital initiation exposes patients to excess risk of early postdischarge clinical worsening an

152 a BMI of 22.6 to 25.0, whereas there was no excess risk of either death from any cause or cause-spec

153 ng kidney donation may be associated with an excess risk of end-stage kidney disease and death.

154 These new data demonstrate that much of the excess risk of ESRD in African American individuals is a

155 cioeconomic status relate importantly to the excess risk of ESRD in African-American men compared wit

156 and accounted for a large proportion of the excess risk of ESRD observed in African compared to Euro

157 The absolute excess risk of events included in the global index was 1

158 isk susceptibility genes explain <40% of the excess risk of familial ovarian cancer.

159 s risk of all-cause mortality, and twice the excess risk of fatal and nonfatal vascular events, compa

160 The excess risk of fever after TIV and PCV13 was 20 and 23 p

161 ior exposure in utero was associated with an excess risk of food sensitization at age 4 years (OR 1.4

162 There was an excess risk of genitourinary tract cancers among recipie

163 of hepatitis B seroconversion but are at no excess risk of graft failure or short-term morbidity or

164 Excess risk of having an AAA according to a family histo

165 Second, there is no significant excess risk of having breast cancer diagnosed 10 or more

166 ll results suggest that there may be a small excess risk of HCC in individuals with GSTT1 null and po

167 ndom-effects meta-analyses suggested a small excess risk of HCC with GSTT1 null (odds ratio (OR) = 1.

168 Since the excess risk of heart disease falls rapidly after the ces

169 nge (> or =30 kg/m(2)) is associated with an excess risk of heart failure (HF).

170 We aimed to determine the excess risk of heart failure in individuals with type 1

171 f the cytokine network may contribute to the excess risk of heart failure in these patients.

172 This excess risk of hemorrhagic stroke is particularly high i

173 There was no evidence of excess risks of hepatitis (21 [0.5%] vs 18 [0.4%]), gall

174 The excess risk of hepatoblastoma was associated with low bi

175 The excess risk of HF among RA patients is not explained by

176 diographic evaluation are associated with an excess risk of HF and may predict post-LTx survival.

177 The excess risk of HF associated with CKD was particularly l

178 The apparent excess risk of HS in patients with previous IE was expla

179 No excess risks of hypercalcemia or other adverse events we

180 The excess risk of hypokalemia with chlorthalidone was atten

181 cting results(11-13), and concerns about the excess risks of ICH associated with lowering LDL-C(14,15

182 The corresponding absolute excess risks of ICVT 1 to 28 days after ChAdOx1-S were 0

183 mediate variables that explained the highest excess risk of IHD from genetically determined obesity w

184 ure with 7%, and remnant cholesterol with 7% excess risk of IHD.

185 Among 4 746 518 vaccine recipients, no excess risk of immune thrombocytopenic purpura diagnosis

186 Excess risks of immune thrombocytopenic purpura and Guil

187 ected by a higher SCr, is associated with an excess risk of incident dementia among individuals in go

188 The excess risk of incident heart failure in black women is

189 a than are their non-pregnant peers, and the excess risk of infection varies with gravidity.

190 ients treated with tocilizumab, there was no excess risk of infections compared with standard therapy

191 Current international migrants had no excess risk of injury in the past 12 months compared to

192 The relative excess risk of interaction was -0.34 (95% CI: -0.60, -0.

193 The relative excess risks of interaction, attributable proportion of

194 r baseline stroke severity, but the absolute excess risk of intracerebral haemorrhage increased with

195 We found limited evidence for an excess risk of intrahepatic, but not for extrahepatic, b

196 e benefits of RV5 and RV1 outweigh the small excess risk of intussusception.

197 dent colorectal cancer, but we did see a 19% excess risk of invasive breast cancer among those with A

198 acute coronary syndrome, diabetes conveys an excess risk of ischaemic cardiovascular events.

199 The HRs indicate excess risk of ischemic stroke was apparent in all categ

200 obese population controls, RYGB patients had excess risks of ischemic stroke [HR = 1.57 (95% CI 1.08-

201 Among 23,118,656 singleton live births, the excess risk of IUGR among Black women, Hispanic women, a

202 (APOL1) variants G1 and G2 contribute to the excess risk of kidney disease in individuals of recent A

203 n Apolipoprotein L1 (APOL1) can explain most excess risk of kidney disease observed in African Americ

204 Survivors of childhood cancer are at excess risk of late mortality even 40 years from diagnos

205 .29-3.13) were both associated with moderate excess risks of later ASDs, whereas the HR for later ASD

206 We aimed to assess the excess risk of leukaemia and brain tumours after CT scan

207 in the early years, provided evidence of an excess risk of leukemia associated with occupational rad

208 anced disease outweighs the relatively small excess risk of leukemia.

209 Coinfection with S. mekongi resulted in excess risk of liver fibrosis and left liver lobe enlarg

210 imate the age-specific risk of infection and excess risk of LTBI from household and community exposur

211 Estimates of the relative excess risk of lung cancer mortality due to interaction,

212 The excess risk of lymphoma attributed to psoriasis was 7.9/

213 The aim of this study was to estimate excess risk of M. tuberculosis infection among household

214 There were significant excess risks of major coronary event (2.44, 95% CI 2.18-

215 The excess risks of mental, physical, and social health outc

216 robiota profile was associated with a 2-fold excess risk of metabolic syndrome, driven by increase in

217 = .03) were independently associated with an excess risk of MGUS.

218 with DM between 1998 and 2010; however, the excess risk of MI incidence remains 3 to 4x greater in p

219 er, for probands with minimal disability, no excess risk of migraine in female relatives was observed

220 le migraine probands, there appears to be an excess risk of migraine with aura.

221 e largest study to date, we suggest that the excess risk of MM in African Americans results from an i

222 or = 15th percentile was associated with an excess risk of mortality (risk ratio = 1.23; p < .001) w

223 cholesterol, the absolute risk and absolute excess risk of mortality for current smokers at baseline

224 be used to identify groups of children with excess risk of mortality from infection.

225 The authors conclude that the excess risk of mortality from motor vehicle accidents th

226 Despite the excess risk of mortality in young women (</=55 years of

227 Overall, findings did not indicate excess risk of mortality or severe morbidity among child

228 It has been hypothesized that the observed excess risk of multiple myeloma (MM) among obese persons

229 herbicides, fungicides) are associated with excess risk of multiple myeloma and its precursor state,

230 Pesticides are associated with excess risk of multiple myeloma, albeit inconclusively.

231 ity and black race have been associated with excess risk of multiple myeloma.

232 The excess risk of myopathy was only two per 10,000 patients

233 r discharge (HR 1.07 [1.05-1.09]), driven by excess risk of non-cardiovascular death (HR 1.25 [1.21-1

234 PBCT or RT is associated with a significant excess risk of non-TC mortality, and increased risks eme

235 Similar to cardiac disease, the excess risk of noncardiac vascular disease in RA is like

236 An excess risk of nonmelanoma skin cancer was observed subs

237 No excess risk of other vascular and nonvascular outcomes w

238 ight indicate an association with HPV, while excess risks of other cancers could point to differences

239 pulses, balloon inflation is associated with excess risk of overinflation and adverse events (vessel

240 D status may explain nearly one-third of the excess risk of PAD in black compared with white adults.

241 Thus, the excess risk of PAD in blacks remains unexplained and req

242 a frequent event that is associated with an excess risk of periprocedural stroke.

243 Excess risk of physical disease and mortality has been o

244 No reported excess risks of pneumonia (5% in the placebo group, 6% i

245 alkylating chemotherapy carries little to no excess risk of POF.

246 ical factors showed approximately three-fold excess risk of post-HCT mortality with chr17p CNLOH in C

247 (SES) is an important factor associated with excess risk of postoperative morbidity and death.

248 However, the magnitude of excess risk of premature death and incident complication

249 Hospital-based series indicate an excess risk of progression from MBL to chronic lymphocyt

250 Excess risk of psychiatric illness associated with child

251 The excess risks of PTD were also observed in maternal fixed

252 The excess risk of recurrent coronary events after MI was pr

253 severe acute and any cGVHD, without apparent excess risks of relapse or nonrelapse mortality, disting

254 Preliminary investigations have revealed excess risk of renal mortality in the population living

255 confirmed multiplex families had significant excess risk of rheumatoid arthritis.

256 s explained 65.3% (95% CI 37.9-92.8%) of the excess risk of SCD in blacks in comparison with whites.

257 An excess risk of second malignancies has been reported in

258 The excess risk of second malignancy after Hodgkin disease c

259 The excess risk of second malignancy after Hodgkin disease i

260 r 15 and 20 years, there was a 2.3% and 4.0% excess risk of second malignancy per person per year.

261 2 years, the relative risk (RR) and absolute excess risk of second malignancy were 4.6 and 89.3/10 00

262 king (1.19 [1.09-1.29]) were associated with excess risk of sepsis hospitalization in women, compared

263 des overall population benefit, there was an excess risk of severe dengue in seronegative vaccinees.

264 gh patients with cardiovascular disease face excess risks of severe illness with coronavirus disease-

265 The percentage of excess risk of SGA birth that was mediated was 7% in Bla

266 height with poor GWG was associated with an excess risk of SGA birth, while high GWG combined with e

267 The adjusted excess risk of SIEs in nonbreastfed infants was large be

268 The excess risk of small airway disease in female mice after

269 Standardized incidence ratios determined excess risk of SMNs in the GI tract compared with that o

270 x and oropharynx cancers carried the highest excess risk of SPM.

271 t trimester of pregnancy would mark women at excess risk of spontaneous preterm birth (sPTB) and exam

272 se and male sex were strongly linked with an excess risk of squamous-cell cancers of the buccal cavit

273 This vasculopathy may explain some of the excess risk of stroke among African Americans.

274 The excess risk of stroke associated with diabetes is signif

275 The excess risk of stroke attributable to psoriasis in patie

276 Whether and to what extent the excess risk of stroke conferred by diabetes differs betw

277 erapy in both study groups and estimated the excess risk of stroke death associated with nonadherence

278 Simon Broome Register Group did not find an excess risk of stroke mortality for subjects with clinic

279 The excess risk of stroke remained unchanged in analyses tha

280 elevation in these markers is predictive of excess risk of subsequent adverse cardiac events.

281 ence ratios were calculated to determine the excess risk of subsequent breast cancer compared with th

282 ratio, 4.31) was attributable entirely to an excess risk of suicide with a firearm (standardized mort

283 The relative excess risk of T2DM was 4.78 for individuals who smoked

284 minority ethnic populations in England have excess risks of testing positive for SARS-CoV-2 and of a

285 Prior/current users had no excess risk of the composite end point after adjustment.

286 These results indicate that any excess risk of these cancers, even from relatively high

287 Recent studies have uncovered excess risks of these cardiotoxic events, especially in

288 A nonsignificant excess risk of thyroid cancer was detected in the irradi

289 The excess risk of TIMI major bleeding with ENOX versus UFH

290 We calculated a risk difference (excess risk) of TM and ADEM for each vaccine.

291 s, statin therapy is associated with a small excess risk of transaminase elevations, but not of myalg

292 Excess risks of tumors of the hemopoietic and lymphatic

293 low-dose quetiapine was not associated with excess risk of type 2 diabetes in comparison with SSRIs.

294 in African Americans may contribute to their excess risk of type 2 diabetes relative to whites.

295 ists, or anticoagulants produces significant excess risk of UGIB.

296 disorders seemed to account for some of the excess risk of unnatural death among people with dual-ha

297 Most of the excess risk of vascular mortality due to smoking in wome

298 However, because the excess risk of venous thromboembolic events (VTEs) with

299 The threshold excess risk of very late DES thrombosis compared with BM

300 models, liraglutide was not associated with excess risk of WRF compared with placebo (odds ratio, 1.