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3 R), we identified a single residue, D164, in exfoliative toxin A (ETA) that acts as a molecular "swit
4 unctionally address this hypothesis, we used exfoliative toxin A (ETA) to inactivate Dsg1 in Dsg3-/-
8 on cleavage of Dsg1 by a bacterial protease, exfoliative toxin A, which removes residues 1 to 381 of
11 -1, staphylococcal enterotoxins A and B, and exfoliative toxin-A, as well as staphylococcal protein A
12 exfoliative toxin to inactivate Dsg1 but not exfoliative toxin alone activate p38, suggesting that p3
15 These data suggest that the specificity of exfoliative toxin cleavage of desmoglein 1 resides not o
17 A resolution crystal structure of the other exfoliative toxin, ETB, which is 40% identical to ETA.
19 tively little is known about exactly how the exfoliative toxins (ETs) cause SSSS, much has been disco
23 glein 1 completely inhibited its cleavage by exfoliative toxin, even after calcium was added back.
24 urther our understanding of the mechanism of exfoliative toxin-induced pathology and suggest novel st
28 he stratum corneum of skin by elaboration of exfoliative toxin, which hydrolyzes only one peptide bon