ライフサイエンスコーパス: expansion

1 f multiple self-antigens that promote B cell expansion.

2 tes muscle growth and neuromuscular junction expansion.

3 ing of fluorescent proteins after 20x linear expansion.

4 iods of organ growth, cell division and cell expansion.

5 enes that are good candidates for phenotypic expansion.

6 that challenge its continued persistence and expansion.

7 hing capillaries from branching to cavernous expansion.

8 ng of F-actin across cells for lamellipodial expansion.

9 y's response threshold until after rapid jaw expansion.

10 ir and/or recombination may contribute to TR expansion.

11 espite decreased OCC from substantial volume-expansion.

12 lop hydrogels with highly tunable volumetric expansion.

13 ares conserved features of human neocortical expansion.

14 out prior GC experience or detectable clonal expansion.

15 TMSiPhe) into proteins, through genetic code expansion.

16 teins starts a vicious cycle of a prion-like expansion.

17 ts to the health care system may hinder PrEP expansion.

18 etric detection of absorption-induced sample expansion.

19 may be further amplified by future cropland expansion.

20 set of auxin inducible genes related to cell expansion.

21 sodium polysulfides and withstand volumetric expansion.

22 2) g(-1)) and exhibits negative area thermal expansion.

23 observed widespread millimeter-scale clonal expansions.

24 sible spatial origins of regional population expansions.

25 technique based on Taylor and Fourier series expansions.

26 in the same pathway to drive triplet repeat expansions.

27 interspecific competition dramatically slows expansion across a landscape over multiple generations.

28 rved patterns of geographical range loss and expansion across continents.

29 ted its subsequent dramatic geographic range expansion across most of tropical Africa.

30 thickness (CTh) and surface area in C9orf72 expansion adult carriers compared to healthy controls to

31 wnt1 was required for tail expansion after mob4 inhibition and dynamically reestabl

32 s on their application as refrigerants, foam expansion agents, aerosol propellants, and precision sol

33 Our results provide strong evidence that map expansion alone does not imply improved perception.

34 Climatic changes can induce geographic expansion and altitudinal shifts in the distribution of

35 nation, which could be coupled with cytokine expansion and contraction.

36 uals' ties undergo an initial cycle of rapid expansion and contraction.

37 ponses was observed in regard to lymphoblast expansion and cytokine production (IFN-gamma, IL-2, and

38 t model for understanding how cell division, expansion and differentiation are coordinated during org

39 T cell expansion and differentiation are critically dependent o

40 ry genes causing changes in anisotropic cell expansion and division patterns [3-5].

41 mutations that synergized to promote clonal expansion and dominance.

42 liferating intracellular S aureus led to the expansion and eventual rupture of mast cells, resulting

43 zymes had positive effects on vessel element expansion and fiber intrusive growth.

44 the original TBM model for cerebral cortical expansion and folding.

45 latory signals by agonistic Abs enhances the expansion and function of tumor-infiltrating lymphocytes

46 eoclasts at the early stage of rapid palatal expansion and further facilitate bone formation during r

47 cts of these defenses in the form of hindgut expansion and gut melanization.

48 cultured with IL-12 cytokine during in vitro expansion and highly effective in vivo if Ag is not limi

49 ion of protons results in a large structural expansion and increased carrier density, leading to an e

50 autoantibodies, causing retro-orbital tissue expansion and inflammation.

51 ary calcification hinders stent delivery and expansion and is associated with adverse outcomes.

52 The authors discovered human-unique expansion and maintenance of cerebellar germinal zones,

53 tigating socioeconomic factors of irrigation expansion and may guide future research and resources to

54 oductive success, they could be vital to the expansion and persistence of range-shifting species.

55 d auxin increase balances wound-induced cell expansion and restorative division rates in a dose-depen

56 n deform to remain ultraconformal during the expansion and shrinkage of micro-sized Li metal particle

57 erior to Wnt3a conditioned media in organoid expansion and single-cell organoid outgrowth.

58 s, economies and cultures incite consumption expansion and the structural imperative for growth in co

59 cilitates type IV collagen removal during BM expansion and tissue growth.

60 ell RNA sequencing, which demonstrate clonal expansion and unique functional states of B cells in res

61 etiological relationship between HTT repeat expansions and FTD/ALS syndromes and indicate that genet

62 ed opportunity to study mechanisms of repeat expansion, and a framework for evaluating the roles of V

63 to normal B cell responses, malignant B cell expansion, and generic principles relating to receptor i

64 increased airway epithelial activation, ILC2 expansion, and T(H) 2 differentiation.

65 logies, including fibrosis, mesangial matrix expansion, and tubular hypertrophy were observed in 0-co

66 ced by unfamiliar carotenoids during a range expansion are repeatedly converted into precise coadapta

67 cific traits, and more than 40 tandem repeat expansions are known to cause neurological disease.

68 RNA repeat expansions are responsible for more than 30 incurable di

69 Repeat expansions are responsible for over 40 monogenic disorde

70 d catch-per-unit-effort are higher since the expansions began.

71 ntact removal enabled 10 to 25 times greater expansion beyond GSK-3beta inhibition alone.

72 ansion is age-dependent, tissue-specific and expansion-biased.

73 involves a complex interplay among cell-wall expansion, biosynthesis, and, in specific tissues, secon

74 gic individuals are not deleted, but have an expansion block that can be released by impairing regula

75 The addition of IL-12 during in vitro expansion boosts low-avidity T cell responsiveness, tumo

76 is leading to widespread heterogeneous shrub expansion, but impacts of these habitat changes on range

77 Expansion by continuous passaging induced replicative ce

78 ents from early-adopter states (ACA Medicaid expansion by January 2014) and 785 patients from nonadop

79 either promote or antagonize heterochromatin expansion by removing H3K4me or H3K9me respectively.

80 may limit gluteofemoral adipose tissue (AT) expansion by suppressing adipogenesis and increasing glu

81 nucleotide repeats (TRs) can exhibit dynamic expansions by integer numbers of trinucleotides that lea

82 elates of altered pain perception in C9orf72 expansion carriers were the bilateral thalamus and stria

83 ammatory intrathecal environment in HTT gene expansion carriers.

84 eta and IL-18 and concurrent late CAR T cell expansion characterized the HLH-like syndromes occurring

85 viors in vivo, a variable we have termed the expansion coefficient.

86 3 dose-escalation design allowing for a dose expansion cohort of up to 14 additional patients with a

87 p) using a 3 + 3 dose escalation design with expansion cohorts.

88 among this cohort suggests this novel repeat expansion configuration is a founder effect in this popu

89 xpansion of pathogenic Candida species; this expansion consisted of a complex dynamic between multipl

90 Both scenarios facilitate range expansion, contraction or stability depending on the str

91 The extent of expansion correlates with disease progression and format

92 We found that allele surfing from range expansion could explain the distribution of 39% of the c

93 An in vitro expansion culture assay was also used to analyze memory

94 The BSP framework revealed population expansions, dated after the last glacial maximum.

95 ragile X-related disorders (FXDs) are Repeat Expansion Diseases, genetic disorders that result from t

96 n and live imaging studies indicate that the expansion does not involve an increase in cell prolifera

97 nd inhibition of NET release annulled lesion expansion during endotoxinemia, thus suggesting that NET

98 t fully consistent with heat-induced thermal expansion during illumination.

99 N genes in maintaining differential perianth expansion during mid- and late flower developmental stag

100 sphingolipids and is important for cellular expansion during vegetative growth.

101 We also show the consistency of clonal expansion dynamics between bulk alpha and beta repertoir

102 gical release, originally conceived as niche expansion following a reduction in interspecific competi

103 ular interplay that enables massive hiPSC-CM expansion for large-scale drug screening and tissue engi

104 To disentangle the causal effect of the expansions from confounding factors, we use unaffected c

105 Genetic code expansion (GCE) technologies incorporate non-canonical a

106 Palatal expansion has been widely used for the treatment of tran

107 to apply this process to HSC maintenance and expansion has yet to be explored.

108 fundamental immunological process of clonal expansion, highlighting the parallels between innate and

109 The G4C2 hexanucleotide repeat expansion (HRE) in C9orf72 is the commonest cause of fam

110 GGGGCC hexanucleotide repeat expansions (HREs) in C9orf72 cause amyotrophic lateral s

111 trary to our expectations, we found that map expansion impaired frequency discrimination and delayed

112 IL-1beta and IL-6 during homeostatic T cell expansion in a clinically relevant model of lymphoablati

113 pothalamus, while females showed significant expansion in a distributed set of regions, including the

114 ts with SLE undergo clonal proliferation and expansion in a self-antigen dependent manner, which supp

115 cells may be a useful source to measure CAG expansion in biomarker assays for therapeutic efforts, p

116 al dementia (FTD) is a hexanucleotide repeat expansion in C9orf72 (C9-HRE).

117 e containing an intronic CCTG microsatellite expansion in DM type 2 (DM2), is coordinately expressed

118 system processes, such as wildfire and shrub expansion in drylands.

119 Here, we summarize the evidence for clonal expansion in innate lymphocytes, which has primarily bee

120 FGF2 induces leukemia stem cell expansion in MLL1-rearranged AML.

121 Its expansion in obesity results in increased mortality and

122 tionary rates (phenotypic and molecular) and expansion in phenotypic disparity in reptile evolution.

123 broblasts in the sublining undergoes a major expansion in rheumatoid arthritis that is linked to dise

124 specific ablation of Gja1 restores beta-cell expansion in the aged pancreas.

125 In the eastern eropical North Atlantic, OMZ expansion in the course of global climate change may det

126 S-morph plants, GLO2 promotes growth by cell expansion in the fused tube of petals and stamen filamen

127 degenerative disorder caused by a CAG repeat expansion in the huntingtin (HTT) gene.

128 ines undergo sodium periodate oxidative ring expansion in the presence of formaldehyde and other alde

129 o identify drivers of recent contraction and expansion in their range.

130 Warmer MSAT facilitated shrub expansion in unburned lowlands (r = 0.78, p < 0.001), bu

131 CAR-T cell expansion in vivo was cell dose dependent.

132 is often limited by the extent of CAR-T cell expansion in vivo.

133 analyses of MAIT cells revealed large clonal expansions in older adults and tissues that rivalled, re

134 Disease-associated repeat expansions in other TFs (HOXA13, RUNX2, and TBP) were si

135 is often seen in SCA2, and ATXN2 CAG repeat expansions in the long normal range increase ALS risk.

136 The current expansion includes new entries from the most recent coll

137 MBNL1 in the developing thymus and DM2 CCTG expansions induce similar transcriptome alterations in D

138 DM1), somatic mosaicism of the (CTG)n repeat expansion is age-dependent, tissue-specific and expansio

139 inated conditions, the mechanism for lattice expansion is in fact fully consistent with heat-induced

140 C9orf72 expansion is the most common genetic cause of frontotemp

141 rginine, the inhibitory effect of RGFP966 on expansions is largely bypassed, consistent with the dire

142 roles distinct B cell subsets play in clonal expansion, isotype switching, and memory B cell differen

143 h is significantly slower than the adiabatic expansion law [Formula: see text] Motivated by such obse

144 nsfer, and free space for alleviating volume expansion, leading to superior battery performance.

145 in cancer-including tumor initiation, local expansion, metastasis, and therapeutic resistance-involv

146 Expansion microscopy (ExM) allows super-resolution imagi

147 Here we employ expansion microscopy to study the origins of centriole s

148 Using super-resolution and expansion microscopy, we find that the SG component UBAP

149 We employ a capacity expansion model with integrated assessment of climate an

150 or CANVAS and identified a novel RFC1 repeat expansion motif, (ACAGG)exp, in three affected individua

151 The expansion mutation in the C9orf72 gene is the most commo

152 cally binds slipped-CAG DNA intermediates of expansion mutations, a previously unsuspected target.

153 Twenty-one patients (escalation, n = 12; expansion, n = 9) with advanced chondrosarcoma received

154 nine recently reported non-reference repeat expansions not discoverable via existing methods.

155 an autosomal dominant disorder caused by an expansion of a (CTG)n tract within the 3' untranslated r

156 ases, genetic disorders that result from the expansion of a disease-specific microsatellite.

157 that males showed statistically significant expansion of a region of the hypothalamus, while females

158 Cavitation is the sudden, unstable expansion of a void or bubble within a liquid or solid s

159 Thus, the recent evolution and global expansion of A. aegypti promoted arbovirus emergence not

160 These functional changes may promote expansion of abnormal myeloid progenitors in del(5q) MDS

161 mitigate several problems related to volume expansion of alloying anodes.

162 lopment of a new classification paradigm and expansion of analytical tools.

163 This led to a significant expansion of APCs, resulting in an 11.5-fold increase of

164 K) inhibition results in loss of F-actin and expansion of apical-basal domains, which comes at the ex

165 likely intermediate site along the routes of expansion of Bantu-speaking populations.

166 This protective effect is linked to the expansion of butyrate-producing Bacteroidetes.

167 Our stable isotope data indicates that the expansion of C(4) vegetation opened up new niche opportu

168 at share a common genetic cause, which is an expansion of CAG repeats in the coding region of the cau

169 ental cell-associated antigen enables robust expansion of CAR T cells in an antigen-sparse environmen

170 The largest expansion of CDK groups was, however, in alveolate-speci

171 sion in two dogs may have been due to clonal expansion of cells harboring integrated vectors.

172 probably, as in adults, maintained by clonal expansion of cells infected before ART initiation.IMPORT

173 ially retained after a recent WGD event, and expansion of CHS genes is likely associated with urushio

174 a pressing need for methods facilitating the expansion of computational models to incorporate these n

175 The propagation and expansion of corneal endothelial cells has been widely r

176 t screening capacities, thereby enabling the expansion of detection in the community, as well as in c

177 Here, we describe a simple platform for the expansion of functional mouse HSCs ex vivo for >1 month

178 raits of the G. margarita genome include the expansion of genes for inorganic phosphate metabolism, t

179 under physiological conditions that require expansion of guanine nucleotide pools.

180 d which protocols effectively induce ex vivo expansion of GZMB(+) B cells.

181 g clearance has only a minimal effect on the expansion of HBV-specific naive CD8+ T cells undergoing

182 eage tracing to localize and quantify clonal expansion of hepatocytes in normal and injured liver.

183 Here, we demonstrate massive expansion of hiPSC-CMs in vitro (i.e., 100- to 250-fold)

184 In vivo clonal expansion of HIV-infected T cells is an important mechan

185 acts with RUNX1 and suppresses RUNX1-induced expansion of HSPCs during development through modulation

186 terminal motif inhibitor CPI203 enhanced the expansion of human cord blood HSCs without losing cell v

187 Moreover, inhibition of LAT1 blocks expansion of human gammadelta T cells and IL-17 secretio

188 Expansion of human hematopoietic stem cells (HSCs) is a

189 The peopling of the Americas marks a major expansion of humans across the planet.

190 Our analysis suggests that the widespread expansion of humans through North America was a key fact

191 T cells while suppressing development and/or expansion of immune-suppressive lymphocytes (Bregs and T

192 The expansion of immunotherapies approved for RCCs has gener

193 he eastern Eurasian steppe over time, and an expansion of isotopic niche widths, indicate that histor

194 The same subspecies exhibits expansion of its carbohydrate metabolism gene repertoire

195 w photoactivation modalities, the continuous expansion of lambda-orthogonal tandem photoclick chemist

196 erial molecular patterns and resulted in the expansion of lysozyme-sensitive mucolytic bacteria, incl

197 lerating role of climate change in the range expansion of M. soledadinus, with populations now thrivi

198 etic MR1 ligand, 5-OP-RU, resulted in robust expansion of MAIT cells in the lung.

199 vestigated the effect of LIV during in vitro expansion of MSCs.

200 cell-autonomous defect in the proliferative expansion of myoblasts.

201 inding in CMV-seropositive individuals is an expansion of NKG2C(pos) NK cells.

202 We discover an expansion of odorant-binding-protein genes, some express

203 The recent expansion of oil palm (OP, Elaeis guineensis) plantation

204 should contribute to the systematisation and expansion of our knowledge.

205 Specific, age-dependent expansion of ovalbumin-specific regulatory T cells was o

206 ection experienced a prior marked intestinal expansion of pathogenic Candida species; this expansion

207 The intestinal expansion of pathogenic Candida spp. was associated with

208 s been shown to reverse EAE by promoting the expansion of peripheral and CNS-infiltrating IL-10(+) T

209 ety issue triggering label modifications was expansion of population restrictions (n = 21 [36%]), fol

210 Focused expansion of PrEP use among cisgender MSWs may be an eff

211 Here we show how the expansion of protected areas by national governments sin

212 be offset by enhanced growth associated with expansion of regions with optimal or near optimal Fe and

213 Key to the success of this process is the expansion of sequence and combinatorial diversity to inc

214 ear cells from adults with SLE confirmed the expansion of similar subpopulations in patients with the

215 ation of nanocelluose from wood or the rapid expansion of small hydropower schemes.

216 ng analysis revealed that this was caused by expansion of specific sub-lineages, designated CC17-A1,

217 iller (NK) cell infiltration and oligoclonal expansion of T cells were detected.

218 (Myr) during cooling associated with global expansion of temperate habitats.

219 We report that while there is modest expansion of TH(+) glomus cells in the carotid body upon

220 reducing Gli3 transcription and by enabling expansion of the 5'Hoxd second expression phase, thereby

221 4H-1,2-oxazines via a Cloke-Wilson-type ring expansion of the aryl-substituted cyclopropane carbaldeh

222 hic normal pressure hydrocephalus (iNPH), an expansion of the cerebrospinal fluid (CSF)-filled brain

223 stitutions at the 3,5- or 2,4,6-positions or expansion of the condensed ring system.

224 is remains a key challenge in Brazil despite expansion of the country's internationally recognized Fa

225 s could underlie this aneuploidy peak: rapid expansion of the engrafted HSPC population and bone marr

226 Expansion of the ESKD payment bundle was not associated

227 r prevention guidelines has led to the rapid expansion of the field of dietary patterns and cancer.

228 uris infection caused marked dysbiosis, with expansion of the Firmicutes and Proteobacteria phyla, ne

229 d in the Southern Annular Mode(1,3-6) and an expansion of the Hadley cell(7,8).

230 e modification: altering the rate of somatic expansion of the HTT CAG repeat or altering the resultin

231 to promote the germinal center response and expansion of the latent reservoir.

232 icroCT analysis showed increased radial bone expansion of the midshaft femur in female N-ERalphaKO al

233 ing winter temperatures are a main driver of expansion of the native, evergreen shrub, Morella cerife

234 te these structures may explain the parallel expansion of the number of Nek family kinases.

235 Expansion of the peanut-specific effector T-cell reperto

236 sease and are specifically biased toward the expansion of the secretory primed basal cell subset in I

237 valence-orbital and relativistic contraction/expansion of the valence/semicore orbitals.

238 In situ expansion of these cells contributes to their abundance,

239 s essential to limit any further local range expansion of this aggressively invasive insect through h

240 Concurrent isolation and expansion of three distinct cardiac-derived interstitial

241 ed autoimmunity was associated with specific expansion of transitional B cells, extrafollicular IgG2c

242 malia is associated with increase in ROS and expansion of tRNA-isodecoders.

243 However, the role of cDC1s in expansion of tumor-specific CD8(+) T cells remains uncle

244 ossil record is central to understanding the expansion of vertebrates in terrestrial ecosystems.

245 r knowledge, this is the first study to show expansion of virus-specific CAR T cells in infected, sup

246 sing surveillance efforts to prevent further expansion of ZIKV.

247 ength (>200 MPa) and a low apparent particle expansion of ~40% upon full lithiation.

248 ata shows that our method can identify large expansions of 41 out of 44 pathogenic repeats, including

249 We review more recent evidence for expansions of recombination suppression beyond mating-ty

250 ed that fibroblast-derived PGE(2) drives the expansion omicronf a population of Sca-1(+) reserve-like

251 and remained isolated from later Bronze Age expansions on the mainland.

252 eceiving alemtuzumab (n=4) showed no UCART19 expansion or antileukaemic activity.

253 ts, such as the tissue thinning coupled with expansion or during the introduction of different cell t

254 essin showed no benefit in limiting hematoma expansion or improving functional outcome.

255 n contrast to the normal colon, where clonal expansions outside the confines of the crypt are rare, w

256 nstruction represents a significant reactome expansion over available reconstructed bacterial metabol

257 The culture system affords 236- to 899-fold expansion over the course of a month and is also amenabl

258 ancing TCR-T effector function, trafficking, expansion, persistence, and memory formation by strategi

259 HOXD13 repeat expansions perturb the composition of HOXD13-containing

260 The expansion phase of tomato fruit growth was also modelled

261 Medicaid expansion policies were significantly associated with an

262 The latter loop expansion produces an effective theory with cubic vertic

263 However, single-cell clonal expansion produces heterogeneous methylomes, thus raisin

264 unstable, with contractions more common than expansions [R.

265 ond to approaching visual looming stimuli at expansion rates that give ample chance to escape from a

266 rome P450 that catalyses the remarkable ring expansion reaction that is required to produce the disti

267 h a mechanism whereby lung lymphatic network expansion reduces lymph stasis and increases clearance o

268 incurred significantly more safety events in expansion relative to nonexpansion states (+1.87% vs -14

269 ders, and undoubtedly more pathogenic repeat expansions remain to be discovered.

270 for applications (such as T-cell culture and expansion) requiring high-avidity molecular interactions

271 ents with gene signatures of such clonotypic expansion respond best to anti-PDL1 therapy.

272 At a tissue level, I propose a differential expansion sandwich plus (DES+) revision to the original

273 screening of FTD/ALS patients for HTT repeat expansions should be considered.

274 d, age-adjusted for the Kutupalong-Balukhali Expansion Site age distribution.

275 go contributed compellingly to A-genome size expansion, speciation and evolution.

276 a, (ii) a fast and efficient dropouts-saving expansion strategy for functional gene modules optimizat

277 nown to induce CD25(+) regulatory CD4 T cell expansion, surprisingly causes robust induction of a sui

278 xExp is an open-source, data-centric lexicon expansion system that generates spelling variants of lex

279 sitate specific types of test such as repeat expansion testing.

280 efforts to dissect underlying mechanisms of expansion that may differ between the brain and peripher

281 te the potential impacts of this planned LPG expansion (the Master Plan) on population health and cli

282 rding cantilever deflection driven by sample expansion, the principle of our approach is to maintain

283 ffect spatial genetic structure during range expansions, the resulting patterns and their impact on n

284 of CD133+ cells by controlling their clonal expansion through the Wnt-regulator FZD8.

285 sses, from speciation and geographical range expansion to community assembly.

286 osis (steatotic livers) represent a possible expansion to the donor pool, but are frequently discarde

287 Here, we describe updates and recent expansions to CARD and its biocuration process, includin

288 he scenario projections of global urban land expansion under the framework of the shared socioeconomi

289 that defects in both cell division and cell expansion underlie the dwarfism of an Arabidopsis lignin

290 te-like low cytotoxic state, with low clonal expansion, unlike the classical exhausted state observed

291 e microscopy, which revealed a local leaflet expansion upon exposure to elevated concentrations of a

292 The 2014 Medicaid expansion was associated with a significant increase in

293 However, this wave of expansion was far from homogeneous, and climatic factors

294 l cross-linking surface and that T(reg) cell expansion was independent of the antibody Fc region.

295 Medicaid expansion was not associated with an increase in LVAD im

296 The Medicaid expansion was not associated with higher direct oral ant

297 CAG expansion was observed in all tissues, but to different

298 Using a parameterized stochastic model of expansion, we find that this slowdown can persist over t

299 is is a critical failsafe that prevents cell expansion when light and nutrients are plentiful, but wh

300 High temperature promotes guard cell expansion, which opens stomatal pores to facilitate leaf