ライフサイエンスコーパス: expedite

1 e of drug development could be substantially expedited.

2 nd the development of targeted agents can be expedited.

3 's reintroduction programme might be greatly expedited.

4 The Expedited Access for Premarket Approval and De Novo Medi

5 The Expedited Access Pathway was designed as a new program f

6 the population against unsafe products while expediting access to beneficial new devices.

7 technologies for infectious diseases enable expedited accurate microbiological diagnoses.

8 Herein we proposed an Image Downsampling Expedited Adaptive Least-squares (IDEAL) fitting algorit

9 ery Tools (GQT) is an indexing strategy that expedites analyses of genome-variation data sets in Vari

10 e failure rate of clinical trials as well as expedite and lower the cost of drug development.

11 ersion of freeze-thawing test seems to be an expedite and reliable method that can yield in 24 h an e

12 of resting CD4(+) T cells from whole PBMC is expedited and achieved in 3 hours, less than half the ti

13 In an era when the number of expedited and conditional review pathways for newly avai

14 se two research efforts offers significantly expedited and enhanced nanomaterial discovery, optimizat

15 Initial IRB review took 2 to 4 months, with expedited and exempt reviews requiring less time (median

16 ndemic countries are encouraged to increase, expedite, and standardize care based on parasite diagnos

17 ms, 26.0% (95% CI, 21.9%-30.1%) by providing expedited appointments, and 19.8% (95% CI, 16.1%-23.5%)

18 In May 2019, tafamidis received expedited approval from the US Food and Drug Administrat

19 l need or in the interests of public health, expedited approval pathways, including conditional marke

20 l oxides were proposed as markers for a more expedite assess to the impact of postharvest conditions.

21 ns of endpoints in pivotal trials supporting expedited authorisations so that prescribers and patient

22 quantified in human tissues isolated during expedited autopsies.RESULTSSMN protein expression varied

23 nfection, which stimulates vesiculation that expedites bacterial surface exchange and adaptation to t

24 nique insights into disease pathogenesis and expedite bench-to-bedside translation of new therapeutic

25 diabetes; endoplasmic reticulum (ER) stress expedites beta cell failure in this situation.

26 ges will reduce synthetic effort and thereby expedite broader exploration of the magic methyl effect

27 edious and time-consuming task, which can be expedited by computational predictions.

28 racking indicate that these interactions are expedited by enhanced spatial proximity between channels

29 striatum mediates habit formation, which is expedited by exposure to alcohol.

30 cation of pheromones of novel species can be expedited by knowledge of pheromones of related species.

31 f pheromones of invasive pest species can be expedited by knowledge of the semiochemistry of related

32 infections in humans, a search that could be expedited by repurposing currently approved drugs.

33 t the evolution of C2H2-ZFs in metazoans was expedited by the interaction of non-base-contacting resi

34 logenation of alcohols under mild conditions expedited by the presence of substoichiometric amounts o

35 es are publicly available, this approach may expedite cardiotoxicity screening of compounds as divers

36 n efficient team using existing resources to expedite care of the emergent surgical patient.

37 a show that by reducing CD82, KSHV miR-K6-5p expedites cell invasion and angiogenesis by activating t

38 ternatively between the V O layers, offering expediting channels for facile Zn(2+) diffusion.

39 pathways could promote cancer mutations and expedite chemoresistance.

40 , highly effective therapeutic strategy that expedites chronic venous ulcer healing by treating the u

41 The glymphatic pathway expedites clearance of waste, including soluble amyloid

42 nt constituents to optimize drug release and expedite clinical translation.

43 to newer therapies, an earlier end point to expedite clinical trials is needed.

44 es remains a priority, including the need to expedite clinical trials using new methodologies.

45 e database of standardized analyses, thereby expediting clinical validation studies.

46 mega-environments for these traits will help expedite common bean breeding, evaluation, and variety s

47 lications, these tools are now being used to expedite crop and livestock breeding, engineer new antim

48 These salient findings can expedite crop improvement endeavors and the development

49 YC resident physicians.METHODSIRB-exempt and expedited cross-sectional analysis through survey to NYC

50 These results indicate that UGT2B17 expedites CRPC progression by enhancing ligand-independe

51 is one method by which the laboratory might expedite culture results and reduce hands-on time and ma

52 Chromogenic agar can expedite culture results, but technologist review is sti

53 phenotypes through structured ontologies, to expedite curation through semi-automated text-mining app

54 Using Google Earth Engine to expedite data processing tasks, we show that there has b

55 Here we present expedited data from VRC 608, a phase 1 study to evaluate

56 o dominant accounts: enhancement through (1) expedited decision onset, or (2) an increase in the qual

57 omarkers that inform ASD pathophysiology and expedite detection.

58 ficity and scalability, E-Golic+ promises to expedite development of additional sophisticated genetic

59 ar metabolic and regulatory mechanisms would expedite development of bioprocessing applications.

60 ore interdisciplinary research approach will expedite development of complexes with real-world applic

61 This model should expedite development of diagnostics, vaccines, and thera

62 l public health challenges that call for the expedited development and availability of preventive vac

63 infectious complications of illicit drug can expedite diagnosis and medical treatment of persons who

64 or group A Streptococcus (GAS) testing would expedite diagnosis and treatment, reduce patient exposur

65 techniques that rely on enrichment, thereby expediting diagnostics.

66 have been touted as having the potential to expedite diarrhea resolution, recent clinical trials que

67 Depletion of the exosome expedites differentiation of human ESCs into all three g

68 where it is complemented by dimerization and expedites dimer incorporation into growth sites.

69 Expedited discharge due to ICU bed shortage was associat

70 Despite expedited discharge, readmission remained unchanged (PRE

71 of dabigatran for stroke prevention that may expedite discovery and allow ongoing evidence developmen

72 The new GWAS search tool LDtrait will expedite discovery of shared genetic components underlyi

73 e to inactivation of the CMAH gene, possibly expediting divergence of the Homo lineage, due to a part

74 he potential of the embryonic environment to expedite diversion from differentiation priming to enhan

75 on organotypic cultures of human disease to expedite drug and therapy development.

76 al model could serve as a valuable system to expedite drug screening as well as to study intestinal t

77 Accelerated approvals may fail to expedite drugs to market in this setting and further res

78 on pathways is vastly important since it can expedite effective therapeutics.

79 initiated hundreds of clinical trials in an expedited effort to understand, prevent, and treat this

80 irected evolution offer innumerable tools to expedite engineering of strains for optimising biosynthe

81 Swollen conidia did not expedite epithelial transmigration.

82 nce in HFrEF treatment and offer a model for expediting evaluation of new therapies.

83 t lower proximal reabsorption in female rats expedites excretion of a saline load and enhances NCC an

84 However, expedited exposure of a 10-minute ALA incubation time di

85 sure antibiotics are given to patients in an expedited fashion after antibiotic order.

86 ast common ancestor with chimpanzees, likely expediting fitness gains during intergroup conflict.

87 esults, including strong staining, should be expedited for confirmatory BRAF mutation testing.

88 on, bone mass, and bone strength, as well as expedite fracture repair through stimulated endogenous o

89 m with sidelobe filtering, the raw data rate expedites from 17.2 to 18.4 Gbps.

90 d to the development of a common platform to expedite future computational developments, provide stan

91 rrogate broodstock technologies, may further expedite genetic improvement in aquaculture.

92 from unrelated individuals, termed massively expedited genome-wide heritability analysis (MEGHA) and

93 h WGA and microarrays is a promising tool to expedite genomic characterization of target strains in e

94 ylogenetic position and its reference genome expedites genomic research within the family Bromeliacea

95 amine D1 receptors promotes angiogenesis and expedites healing in diabetic wounds.

96 integrating, baculovirus-based vector system expediting highly efficient transient multigene expressi

97 Accurate and expedited identification of scar regions most prone to r

98 ssment in clinical trials and practice could expedite implementation of "treat-to-target" algorithms,

99 could improve hydrogel design rationale and expedite in vitro characterization, therefore facilitati

100 hPSCs to generate cerebral organoids, which expedited in situ myelination.

101 ess to testing, shorten time to results, and expedite initiation of antiretroviral therapy.

102 isinin biosynthesis in A. annua but also may expedite innovation of novel metabolic engineering appro

103 ication of the ancestral MSY3 haplotype will expedite investigation of the mutation leading to the do

104 Moreover, AGE-IAPP can induce normal IAPP to expedite its aggregation process, and its fibrils can al

105 scuity confers kinetic advantages to NTF2 by expediting its facilitated diffusion and reinforces the

106 idneys for transplantation produced ideas of expediting kidney placement for populations with decreas

107 ost research efforts have developed tools to expedite labor- and time-intensive contaminant identific

108 insight into how this expertise develops to expedite learning among its newest members.

109 Schemas can benefit memory by expediting learning and increasing capacity in familiar

110 prove useful to identify patients requiring expedited management.

111 sgenes, factor-free derivatives exhibited an expedited maturing phenotype with canonical responsivene

112 ltiplex cardiac biomarkers in human serum to expedite medical decisions for enhanced patient care.

113 ystems and end-to-end prototypes realized to expedite medicinal chemistry discovery cycles.

114 recently been reported to be a reliable and expedited method for identification of mycobacteria, alt

115 ailable to those who might benefit most from expedited, microscale chemistry.

116 ow that this loss of structural integrity to expedite migration could inhibit mesenchymal cell prolif

117 ulminate in deleterious outcomes and/or that expedite migration to direct endogenous cell-mediated re

118 platelet-derived growth factor-AB (PDGF-AB) expedites migration through native tissue.

119 MALDI-TOF MS has the potential to expedite mold identification, and misidentifications are

120 ieve reductions in tinnitus perception or to expedite motor rehabilitation after suffering an ischemi

121 interact with these heterogeneous sources to expedite N transport to aquatic systems.

122 ation and assembly - will be instrumental in expediting natural product discovery.

123 According to the results, CpG methylation expedites nucleosome assembly in the presence of abundan

124 velopment times across review types (exempt, expedited, or full board).

125 glecaprevir-pibrentasvir therapy results in expedited organ transplantation, rapid HCV suppression,

126 In this review, we explore how PSCs have expedited our understanding of developmental mechanisms

127 er reaction rates allow chlorine radicals to expedite oxidation of hydrocarbons, including methane, a

128 Expedited partner therapy (EPT), the practice of treatin

129 validation studies; the findings apply to 2 expedited pathways and may not be generalisable to produ

130 votal trials supporting products assessed by expedited pathways, surrogate endpoints reduce drug deve

131 ection of resistance-related mutations could expedite patient care and TB eradication.

132 fficacy and pain associated with microneedle expedited PDT.

133 aging mechanism are discussed in terms of an expedited physical aging process, which is largely contr

134 ncentrations during haze episodes would have expedited planetary hydrogen loss, with a single episode

135 propose the concept of dynamic templating to expedite polymer nucleation and the ensuing assembly pro

136 patient anxiety and improving compliance by expediting postsurgical specimen assessment.

137 A coordinated effort is needed to expedite preservation advances that can transform severa

138 NP868R-assisted reovirus rescue will also expedite production of recombinant reovirus for mechanis

139 of new drugs benefiting from at least 1 such expedited program in 2018.

140 d the USA that have created a complex mix of expedited programmes aimed at facilitating faster access

141 To expedite progress in the care of people affected by diff

142 To expedite progress in this regard, a consensus conference

143 of C. parvum oocysts in larger volumes will expedite progress of research by enabling the sharing of

144 To expedite progress towards improved quantitative tools, w

145 d by the institutional review board under an expedited protocol for analyzing anonymous aggregated ad

146 existence of proton collecting antennae for expedited proton transport.

147 oging of personal genetic variation has been expedited, providing improved insights into the key impo

148 eComb (developed in-house), were utilized to expedite pyrosequencing data analysis.

149 growth, fine tuning the solution temperature expedites random curving of ZnO nanorods and forms nano-

150 tural basis of antibody efficacy, which will expedite rational design of vaccines, prophylactics, and

151 dvances to attenuate acute kidney injury and expedite recovery have largely failed.

152 ed flushing protocols should be developed to expedite recovery, minimize health impacts, and reduce c

153 s determined that avoiding physical activity expedites recovery.

154 Screening with high uptake will expedite reductions and will be necessary to eliminate c

155 Decisions based on surrogate end points may expedite regulatory approval but may not accurately refl

156 cause of the availability of safety data and expedited regulatory approval.

157 -gene expression after sleep deprivation and expedites REM-sleep recovery.

158 ve compounds that can potently stimulate and expedite reparative dentin formation is still underexplo

159 ath lab) at the STEMI receiving hospital may expedite reperfusion, but can be logistically challengin

160 efore analysis, offering an effective way to expedite research in drug discovery, toxicology and cell

161 can be made, and provides a robust bases for expedited risk/benefit.

162 Key transformations for this expedited route include an enantioselective organocataly

163 Collectively, these data validate an expedited route to vaccine delivery or optimal T cell ex

164 However, hyperactive or expedited S phase entry causes replication stress, DNA d

165 ce for the medical and research community to expedite scientific advancement through shared learning,

166 ontology, disease categories) and therefore expedite scientific discoveries.

167 nal potential, as they can be widely used to expedite scientific endeavors for the betterment of huma

168 and handle solids in multichannel format and expedite screening of enzyme immobilization conditions.

169 ool that monitors p53 sumoylation status and expedites screening for drugs that enhance p53 sumoylati

170 While hotspot engineering has expedited SERS development, it is still challenging to d

171 ulations and machine learning techniques can expedite significantly the materials discovery process.

172 The validated method thus minimized and expedited simultaneous SE and SF analysis.

173 Disturbances may expedite species' recruitment into new sites, but they h

174 specific diagnostic techniques are needed to expedite specific treatment of bacterial skin infections

175 Because of its ability to expedite specimen identification and species delineation

176 Suppression of Dh44 signals in the brain expedites sperm ejection from the uterus, resulting in m

177 y should facilitate its wide application and expedite structural studies of prions.

178 Our unique approach has the potential to expedite studies on transcription of any gene in the con

179 and any causality dimension, used methods to expedite study selection, data extraction, and quality a

180 first time, IRIS-EDA provides a framework to expedite submission of data and results to NCBI's Gene E

181 accurate theoretical prediction of pI would expedite such analysis.

182 ting using CRISPR/Cas9 have the potential to expedite sustainable genetic improvement in aquaculture.

183 utility of the method is demonstrated in an expedited synthesis of the trifluorinated alpha-phenyl a

184 Research that expedites synthetic access to NP motifs can prevent homo

185 molecular biology techniques may enhance and expedite target discovery and drug development for cance

186 ible solution to this challenge by providing expedited target screening and validation through switch

187 his program provides a way to facilitate and expedite the analysis of subcellular RNA localization fo

188 o the Lamm equation, with the application to expedite the approach to sedimentation equilibrium.

189 ghs with synthetic budding yeast chromosomes expedite the creation of synthetic mammalian chromosomes

190 rk reveals a promising candidate approach to expedite the design of large-scale metasurfaces in a lab

191 cid computing tools are further developed to expedite the design process of pattern generation, we an

192 have developed an online tool, CHOPCHOP, to expedite the design process.

193 synthetic biology provide an opportunity to expedite the development of C. reinhardtii as an industr

194 he unique ability of photoredox catalysis to expedite the development of completely new reaction mech

195 ed mouse models (GEMM) have the potential to expedite the development of effective new therapies; how

196 These findings could expedite the development of effector-linked gene drives

197 These findings could expedite the development of gene drives to suppress mosq

198 The resources presented here will expedite the development of improved black and red raspb

199 ease chromosome mis-segregation rates should expedite the development of new therapeutic strategies t

200 ropose future research directions that would expedite the development of new treatments.

201 f human monocyte-Toxoplasma interactions can expedite the development of novel human toxoplasmosis co

202 mechanisms of chromosome segregation and may expedite the development of novel therapeutic strategies

203 we propose a crowdsourcing effort that could expedite the development, validation, refinement, and se

204 The use of machine learning techniques to expedite the discovery and development of new materials

205 This screening method will expedite the discovery of drug targets and resistance me

206 sents an alternative strategy to potentially expedite the discovery of new antimicrobial drugs.

207 mputational methods for PTM site prediction, expedite the discovery of new malonylation and other PTM

208 together with our proposed methodology, will expedite the discovery of non-classically secreted effec

209 To expedite the discovery of novel substrates, computationa

210 niaturized screening procedures/platforms to expedite the discovery of photochemical reactions remain

211 In this study, to expedite the enzymatic conversion of a hydrophobic subst

212 Surrogates for overall survival (OS) could expedite the evaluation of new adjuvant therapies.

213 espiratory syndrome coronavirus 1 has helped expedite the evaluation of several promising therapies,

214 To expedite the evaluation of vaccines against paratyphoid

215 further dissemination of study methods, and expedite the exchange of ideas among researchers.

216 We have built an R package, genomation, to expedite the extraction of biological information from h

217 ctional assays, SAS mutational libraries can expedite the functional assessment of genetic variation.

218 cals critical to these reactions in order to expedite the future development of new site-selective, i

219 Score statistics were developed to expedite the genome-wide computation.

220 IP-Frag-Map approach should prove general to expedite the identification and optimization of small mo

221 ification, reduces consumable usage, and may expedite the identification of E. coli in clinical speci

222 screening platform is also general and will expedite the identification of more unique luciferases a

223 Taken together, DTG aims to expedite the identification of small molecules from the

224 elerate the analysis of T cell responses and expedite the identification of specific ligands.

225 To expedite the molecular diagnosis of NMDs, we designed an

226 ed approach is a powerful analytical tool to expedite the optimization process while using reduced re

227 To move the field forward and to expedite the pathway from discovery to regulatory approv

228 More stringent PM(2.5) reduction targets expedite the phaseout of high emission intensity sources

229 of feature lists after initial processing to expedite the process of data curation.

230 research, catalyze clinical innovations, and expedite the realization of precision medicine.

231 To further expedite the released N-glycan sample preparation, rapid

232 (Lipo-15-epi-LXA4) or free 15-epi-LXA4 will expedite the resolving phase in post-MI inflammation.

233 To expedite the review of semi-automated probability maps o

234 positive screening results, and costs and to expedite the start of therapy for those confirmed to be

235 bstrate scope portend that this process will expedite the syntheses of chiral heterocyclic amines of

236 pment of an organotrifluoroborate reagent to expedite the synthesis of the requisite trifluoromethyl-

237 In order to expedite the synthesis, a divergent synthetic strategy w

238 s been going through several developments to expedite the synthetic process and to obtain the target

239 f SARS-CoV-2 infection and pathogenesis will expedite the testing and deployment of therapeutics and

240 h datasets are shared and which are not, may expedite the transition to community-wide data sharing.

241 nhancing the BLA-to-FSI transmission in vivo expedited the acquisition of cocaine self-administration

242 protocol improved the SLAMF6 -/- T cells and expedited the antitumor response even further.

243 d oxidation of vascular lipids, atorvastatin expedited the clearance of vascular lipids.

244 gmentation after cocaine self-administration expedited the development of incubation of cocaine cravi

245 h-throughput sequencing of RNA (RNA-seq) has expedited the exploration of these regulatory variants.

246 Advances in genomics have expedited the improvement of several agriculturally impo

247 Recent advances in genome editing have expedited the precise insertion of fluorescent protein t

248 ion doses are above 15 mg kg(-1) : high dose expedited the renal excretion and shortened the blood re

249 owth of the printed electronics industry has expedited the search for advanced memory materials suita

250 tion have revolutionized science and greatly expedited the systematic characterization of genes.

251 This work not only expedites the development of anti-influenza strategies,

252 sothermal segregation mechanism that greatly expedites the growth rate.

253 When alpha = 0, the involved protein expedites the reaction to the maximal degree; when alpha

254 RNA polymerase (RNAP) expedites the recognition of DNA damage by NER component

255 l habenulo-interpeduncular (dHb-IPN) pathway expedites the return of locomotor activity following an

256 n contrast, the presence of genomic crowders expedites the target search process by transporting the

257 es, where a single, high-conductivity buffer expedites the transition from cell lysis to protein elec

258 rowave-assisted protocol with the purpose of expediting the catalytic reaction.

259 )F-fluoromisonidazole dPET, with the goal of expediting the clinical implementation of (18)F-fluoromi

260 ountering concerns that they might be simply expediting the detection of advanced stage disease.

261 e as a valuable next-generation platform for expediting the development of CNS therapeutics.

262 OH* and COOH* species plays a vital role in expediting the electrooxidation process, which relates w

263 the availability of whole-exome sequencing, expediting the identification of relevant genes and comp

264 the oncogenic mechanisms of RNA editing and expediting the identification of therapeutic targets in

265 d chemical properties, thereby substantially expediting the pace of drug development.

266 moter cassettes into a gene cluster, thereby expediting the reengineering process.

267 eptor molecules would be proven valuable for expediting the search of room-temperature "displasive-ty

268 agronomic and environmental advantages will expedite their dissemination in subsurface environments.

269 ) ranked positions, which can facilitate and expedite their experimental characterization.

270 ltrasmall (CdSe)34 nanocrystals, which could expedite their potential applications in solid-state dev

271 e to degradation and significantly increases/expedites their attrition, leading to apoptosis.

272 a streamlined laboratory work flow and will expedite therapeutic and infection control decisions.

273 These studies may help expedite therapeutic development and invigorate studies

274 Use of this end point may expedite therapeutic development with the intent of brin

275 how lessons learned from dengue research may expedite therapeutic strategies for Zika virus.

276 y available interactive resource, Hemap, for expediting therapeutic innovations in hematologic malign

277 Non-human primate models will expedite therapeutics and vaccines for coronavirus disea

278 To expedite this 'timely diagnosis', and that also at an ea

279 To expedite this method, we used bioluminescent E. coli in

280 eak, we designed and implemented a system to expedite this testing and the results here from the firs

281 To expedite this translation, we explored the feasibility o

282 ons between data types have proven useful in expediting this process, for example, in prioritizing ca

283 Development of LP99 from a fragment hit was expedited through balancing structure-based inhibitor de

284 yndrome coronavirus 2 (SARS-CoV-2) are being expedited through preclinical and clinical development.

285 cAST delivers an expedited time-to-readout by means of optical assessment

286 e ReEBOV Antigen Rapid Test (ReEBOV RDT) was expedited to provide a point-of-care test for suspected

287 Level of review ranged from full board, expedited, to exempt.

288 riving the adoption of ATS were the need for expedited toxicology information, the need for reduced t

289 Incentivized attention tasks could expedite training and evaluate the impact of attention o

290 ntations, this demands a 2 team approach and expedited transfer of the allograft, limiting the recove

291 terminal domain and diphtheria toxin A chain expedited translocation.

292 l antigen lateral flow assays (CrAg LFA) may expedite treatment of HIV-associated cryptococcal infect

293 over new or repurpose existing compounds and expedite treatment options.

294 The additional advantage to expedited treatment was that the procedure was virtually

295 of active gastrointestinal bleeding, thereby expediting treatment initiation.

296 (PSA)-based composite end point, may further expedite trial completion.

297 remarkable worldwide collaborative effort to expedite trials of two candidate Ebola virus vaccines: c

298 enerate important data exist and are used to expedite vaccine and therapeutic development and to supp

299 ld prompt serologic testing for CRMP5 IgG to expedite vision-sparing immunosuppressant therapy and a

300 ggest guidelines for future research to help expedite well-founded PA recommendations for the public.