ライフサイエンスコーパス: expensive

1 f being time-consuming, poorly sensitive and expensive.

2 detectors, which makes the sensor bulky and expensive.

3 ical calculations, which are computationally expensive.

4 provide answers but are computationally very expensive.

5 ver, direct and indirect treatment costs are expensive.

6 nome-wide TSS profiling are laborious and/or expensive.

7 scale monitoring is logistically complex and expensive.

8 millions of dollars, which is prohibitively expensive.

9 y in three dimensions but is computationally expensive.

10 desired DNA template is often prohibitively expensive.

11 whole genome duplex sequencing prohibitively expensive.

12 structure features which is computationally expensive.

13 atures make NH(3) production facilities very expensive.

14 ically improved but are more computationally expensive.

15 Nucleic acid amplification tests (NAATs) are expensive.

16 baiting; however they are time consuming and expensive.

17 urrent analytical tools tend to be bulky and expensive.

18 pectacular aerial displays are metabolically expensive.

19 aulic models are infeasible or prohibitively expensive.

20 on by NMR spectroscopy is time consuming and expensive.

21 g sites experimentally is time-consuming and expensive.

22 to more consumer electronics and become less expensive.

23 DNA-binding proteins are time-consuming and expensive.

24 y bowel disease ($7.2 billion) were the most expensive.

25 ases has become increasingly challenging and expensive.

26 sorting, and single cell RNA sequencing are expensive.

27 illomavirus (HPV) vaccines are prohibitively expensive.

28 om coastlines are technically unfeasible and expensive.

29 ression to clinical trials is overwhelmingly expensive.

30 to reduce artifacts but are computationally expensive.

31 akes the regular testing of every individual expensive.

32 ctronic devices to be frustratingly slow and expensive.

33 e-art mobile eye trackers that are 100x more expensive.

34 expectancy were smaller (3.4 years) and more expensive ($223,000/QALY gained [95% uncertainty interva

35 a lightweight alternative to computationally expensive 3D architectures.

36 ride (i.e. circumventing the need of feeding expensive additives).

37 er such milder conditions could be much less expensive, allowing production at local sites needing fe

38 ly guide actors in beverage industry to less expensive alternatives.

39 Fecal DNA sampling was the most expensive, although this technique generally performed w

40 of the sample is wasted for analysis of the expensive analytes, without compromising recovery.

41 This method does not require any expensive analytical instrumentation but can achieve hig

42 they have simpler synthetic procedures, less expensive and are more biodegradable than ionic liquids.

43 ng are multi-step, time consuming, requiring expensive and bulky instruments with a constant need of

44 has high potential to improve BP but may be expensive and burdensome for patients, clinicians, healt

45 lays using specialized eye trackers that are expensive and cannot scale.

46 many VR molecular-visualization programs are expensive and challenging to use; work only on specific

47 A goal was to avoid expensive and complicated clarification and fining steps

48 Its diagnosis is expensive and difficult because of lack of adequate reso

49 finally, we show that geosmin, which is both expensive and difficult to obtain, can be substituted by

50 However, compost is expensive and energy intensive to transport, which limit

51 However, renewable hydrogen production is expensive and in limited quantity compared to CO(2) .

52 abies PEP depends on anti-RABV IgG, which is expensive and in limited supply in geographical areas wi

53 ith intravenous immunoglobulin which is both expensive and ineffective in the treatment of POEMS.

54 n of S. oneidensis MR-1 remains complicated, expensive and inefficient.

55 s for assessing drug toxicity, thus reducing expensive and invasive animal testing during clinical tr

56 hods of protein structure elucidation remain expensive and labor-intensive and require highly purifie

57 tional (noble) gas analysis in water is both expensive and labor-intensive.

58 g technology, but still can be prohibitively expensive and laborious when community samples of thousa

59 mercially-available glutamate biosensors are expensive and larger in size.

60 Despite its benefits, Truvada-based PrEP is expensive and needs to be taken once-daily, which often

61 cost of illness could increase, due to more expensive and potent drugs required for treatment.

62 DFBA models are generally computationally expensive and present unique challenges to UQ, as they e

63 marine ecosystems is perceived by many to be expensive and prone to failure, in part explaining its l

64 nts used to aid diagnosis are time and labor expensive and require trained clinicians to administer,

65 Both NMC and NCA contain cobalt, an expensive and scarce metal generally believed to be esse

66 is required in clinical trials, where it is expensive and slow because human central readers are nee

67 onventional PCR while real-time PCR requires expensive and sophisticated instruments.

68 remains a challenge due to the dependence on expensive and specialized equipment.

69 atients at high risk for falls, but they are expensive and their effectiveness is unclear.

70 DNA from liquid biopsies; however, they are expensive and time consuming for clinical use.

71 dimensional, evolves through time and can be expensive and time consuming to measure.

72 te NN parameters with modified base pairs is expensive and time consuming.

73 hey are prone to human error (microscopy) or expensive and time-consuming (polymerase chain reaction)

74 Core flood experiments, however, are expensive and time-consuming and do not allow for pore s

75 Instead of expensive and time-consuming biological experiments, com

76 ales linearly with the number of targets; an expensive and time-consuming feat.

77 ses as labels for training, thereby avoiding expensive and time-consuming pixel-wise manual annotatio

78 s required for regulatory approval and is an expensive and time-consuming process.

79 hanisms between circRNAs and diseases, it is expensive and time-consuming to discover the new circRNA

80 In part, this is due to expensive and time-consuming wet-laboratory experiments,

81 del generation for drug development is still expensive and time-consuming, demanding more target flex

82 g ecological changes in marine ecosystems is expensive and time-consuming.

83 eas sensory analysis by trained panelists is expensive and time-consuming.

84 hese reasons, drug repurposing - both a less expensive and time-efficient practice compared to de nov

85 echnology,however, it is complex, intrusive, expensive and uncomfortable.

86 Yet the use of such expensive and unstable HTMs, together with hygroscopic p

87 Robotic technology is more expensive and whether a robotically assisted approach is

88 need for a lead-in, which is time-consuming, expensive and, in some cases (i.e., open-label antidepre

89 tive to current removal practices, which are expensive and/or ecologically unsafe.

90 avily on fetal tissues, can be prohibitively expensive, and are often complicated to generate.

91 s to measure these parameters are laborious, expensive, and inefficient for handling multiple samples

92 ighlights cellular morphology-is quick, less expensive, and less variable in preparation.

93 The test is expensive, and little is understood about where it fits

94 nalysis of blood serum as an easy, fast, non-expensive, and minimally invasive detection method for d

95 essions, and duodenal biopsies are invasive, expensive, and not a routine monitoring technique.

96 l pathogen detection remains time-consuming, expensive, and of limited sensitivity.

97 Subtissue labeling is prohibitively expensive, and only rough annotations of the entire tiss

98 However, these are expensive, and supply of such kits in sufficient numbers

99 However, attending conferences can be expensive, and the high cost of conference attendance mi

100 ent of biotherapeutic antibodies is complex, expensive, and time-consuming, and to facilitate this pr

101 r, these assays are technically challenging, expensive, and time-consuming, making it difficult to in

102 f platinum as a catalyst-which is scarce and expensive-and ongoing research is focused towards findin

103 eration by the replacement of meat from more expensive animal species with meat from cheaper sources.

104 High-quality annotations are unfortunately expensive as they require field experts to create them,

105 Drug development is expensive, attrition rates are high, and efficacy rates

106 egion-to-region connectivity remain slow and expensive because they require averaging across hundreds

107 ulating taking-off, their most energetically expensive behaviour, to favourable wind conditions.

108 HTS platforms based on radioactivity are expensive, both in terms of reagent cost and disposal.

109 n coverage, copayment assistance, and use of expensive brand drugs may be contributing to these trend

110 The most expensive breaches approach the upper limits of vertebra

111 t of the water may represent the single most expensive burst maneuver found in nature.

112 result, instead of employing a metabolically expensive but durable carbon (C)-based skeleton, flowers

113 Camera sampling was the least expensive, but had large variances.

114 In the base case, SCIT was slightly more expensive, but more effective than SLIT, being the most

115 owever, at $225 000 per year, it is the most expensive cardiovascular drug ever launched in the Unite

116 catheter aortic valve replacement (TAVR) are expensive cardiovascular technologies with potential to

117 mild reaction conditions, in the absence of expensive catalysts, starting from simple reagents, in g

118 gy requires prefunctionalized substrates and expensive catalysts.

119 wever, the drugs used in the ART regimen are expensive, cause side effects, and face viral resistance

120 The use of expensive chiral phosphines is more scattered, but the m

121 choice of conference location-choosing less expensive cities nearer to more Society for Epidemiologi

122 y in resource-limited countries where newer, expensive combinations are not available.

123 evels of detection than the bulkier and more expensive commercial fluorescence plate readers.

124 As a cost-effective alternative to expensive commercial isobaric tagging reagents, we devel

125 t, and plasticity, but is more energetically expensive compared with the jammed phase, which evolved

126 eted but have low adherence because they are expensive, complex, and time-consuming.

127 oinformatics skills or do not have access to expensive computational infrastructure.

128 nstraints have led to systems that are often expensive, cumbersome, and challenging to operate, confi

129 to amino acid bias, remedied at high cost by expensive custom synthesis of oligonucleotides, or throu

130 h HIV-1 burdened by a lifelong commitment to expensive daily medication.

131 solving such equations can be substantially expensive, depending upon their spatial extension.

132 age and optimize the use of more invasive or expensive diagnostic assays.

133 ernative to time-consuming, destructive, and expensive diagnostic procedures, such as immunological a

134 ts added value over conventional, often less expensive, diagnostic imaging methods.

135 r cells to avoid premature activation of the expensive downstream gene expression by filtering input

136 financial toxicity caused by innovative, yet expensive, drugs.

137 time-consuming, manually laborious and often expensive due to the excessive consumption of reagents.

138 While DAA 20% with MAT+ 80% was more expensive (e.g., less cost-saving) than MAT+ 80% alone w

139 While DAA at 20% with MAT+ at 80% was more expensive (eg, less cost saving) than MAT+ at 80% alone

140 to 255 300), reflecting an increase in less expensive electronic media advertising.

141 isconnections, minimizing time-consuming and expensive empirical evaluation.

142 holographic optical tweezers, which rely on expensive equipment and high-powered lasers that can deg

143 r detection of infectious pathogens requires expensive equipment and well-trained personnel, thus lim

144 be processed on-demand, without the need for expensive equipment or cleanroom facilities.

145 lly involve laborious sample preparation and expensive equipment or reagents.

146 proaches that reduce user steps, reliance on expensive equipment, and the system's time-to-result.

147 However, qPCR requires expensive equipment, trained personnel, and significant

148 a neurology subspecialist or specialized and expensive equipment.

149 ensitive and specific, but slow, and require expensive equipment.

150 uirements, laborious sample preparation, and expensive equipment.

151 n, high consumption of reagents and need for expensive equipment.

152 cal obstacles, such as intricate designs and expensive equipment/materials, in the fabrication of wea

153 ains elusive even after extensive (and often expensive) evaluation.

154 re facilities are an effective way of making expensive experimental equipment available to a large nu

155 r several drawbacks, including energetically expensive fabrication, limited availability of certain c

156 he concentration distribution, bypassing the expensive FEM calculation process.

157 nucleic acid quantification without need for expensive fluorescence detection equipment.

158 ed of gene isolation, gene amplification, or expensive fluorescent tag but with polymerase chain reac

159 id histidine is among the most energetically expensive for bacteria to synthesize; therefore, scaveng

160 This process is laborious and expensive for both the computational and laboratory aspe

161 Scan is a serial program and computationally expensive for designing CRISPR guide RNA libraries from

162 ample, but these methods are computationally expensive for large datasets.

163 ical methods for this test are prohibitively expensive for the underprivileged global population due

164 e processes are considered too energetically expensive for widespread deployment.

165 We tested "the expensive germ line" hypothesis by generating germline-f

166 PSCs) have become available and, though more expensive, have lower total misclassification than DBSs.

167 n II receptor blocker) and a newer, but more expensive, heart failure medication (angiotensin II rece

168 ) requires many skilled professionals and an expensive hospital structure.

169 to reduce expression and secretion of other expensive host cell proteins.

170 Genome sequencing technology remains expensive, however, limiting the potential for larger st

171 e and does not require fluorescence signals, expensive imaging equipment or custom-written algorithms

172 tial using time-lapse data collected through expensive imaging hardware.

173 l confinement effects but is computationally expensive in comparison.

174 ve been murdered and buried, is problematic, expensive in terms of human resource and currently has l

175 guration-interaction method is exponentially expensive in the number of electrons.

176 re commonly identified by time-consuming and expensive in vitro neutralization assays.

177 a result, the process is time-consuming and expensive, in particular when developing microfluidic pr

178 ancestries without requiring computationally expensive individual-level genotype data.

179 g more reliable results often require large, expensive instrumentation and specially trained staff.

180 stablished, they are time consuming, require expensive instrumentation, and are limited to small tiss

181 ion of potentially harmful compounds without expensive instrumentation, entrapment of environmentally

182 storage and handling, skilled personnel, and expensive instrumentations.

183 tion in low resource settings as it requires expensive instruments and bioinformatic analysis.

184 It is generally performed using expensive instruments or highly-specific miniaturized se

185 this approach is time-consuming and requires expensive instruments, specialized expertise and a large

186 g, labor intensive and require sophisticated expensive instruments, thus not suitable for point-of-ca

187 sity, time-consuming modification steps, and expensive instruments.

188 es using single-plexed assays with bulky and expensive instruments.

189 er size volumes often requires much time and expensive instruments.

190 properties but does so without the need for expensive interface labeling for training the segmentati

191 hods for diagnosing DMD are often laborious, expensive, invasive, and typically diagnose the disease

192 linical trials comparing deferiprone, a less expensive iron chelator, with deferasirox in paediatric

193 for identifying PPIs are time-consuming and expensive, it is important to develop automated computat

194 ies heavily on staining methods which can be expensive, labor/time-intensive, inconsistent across lab

195 al protein assays are performed using large, expensive laboratory chemistry analyzers that are not am

196 tion limits, but they involve both bulky and expensive laboratory equipment or long and tedious proto

197 arable with that of a BIAcore SPR system, an expensive laboratory gold standard, with significant enh

198 -time noninvasive imaging without the use of expensive large equipment (PET or MRI) is most desirable

199 ngs of this magnitude permit the use of less expensive launch vehicles, installation of additional in

200 defenses against pathogens are energetically expensive, leading ecological immunologists to postulate

201 es for screening and diagnosis, but many are expensive, less feasible or have harmful side-effects.

202 owever, the biosynthesis of PHAs is slow and expensive, limiting their broader applications as commod

203 system does not require specialized buffers, expensive materials, complicated fabrication processes,

204 successfully reproduced the computationally expensive MD results using relatively cheaper DPD simula

205 Mitoribosome biogenesis is an expensive metabolic process that is essential to maintai

206 To minimize the loss of an energetically expensive metabolite and avoid host detection, bacteria

207 atalysts, with maximized atom utilization of expensive metal components and relatively stable ligand

208 ensor is a simple, rapid, selective, and non-expensive method for TBZ measurement.

209 d therapies, it is currently solely based on expensive monoclonal antibodies, which often inflict imm

210 n-making but is currently possible only with expensive motion capture systems and highly trained pers

211 ifficult to be optimized and still relies on expensive noble metal-based catalysts such as Ru or Ir.

212 cal training, extensive data processing, and expensive operational and capital costs.

213 h antibiotics for CDI exist, they are either expensive or cause recurrence of the infection due to th

214 re is less established and can be difficult, expensive or destructive to the initial material(2,9).

215 physiological conditions can be either very expensive or limited in its long-term capability.

216 ted without the use of catalysts, templates, expensive or toxic chemicals, or any external stimuli.

217 Many partial oxidations often need an expensive oxidant such as peroxides or other species to

218 , including lack of mono-selectivity, use of expensive oxidants and limited scope(6-13).

219 A flocked swab performed better than a more expensive paper swab.

220 cost-effective (mutualism) or energetically expensive (parasitism) interactions.

221 ntly introduced drugs that are effective but expensive, patients with heart failure with reduced ejec

222 oup was US$0.27 (95% CI -0.49 to -0.05) less expensive per woman than the placebo group.

223 sed for better performance without bulky and expensive permanent magnets.

224 ght photocatalysis but without the use of an expensive photocatalyst.

225 histicated electrocatalysts, mostly based on expensive platinum group metals.

226 ement the classical established complexes of expensive precious metals and rare-earth elements.

227 the difficulty in bioprocessing them without expensive pretreatment and fuel separation steps, the co

228 dormancy, how they manage the metabolically expensive process of cytokine production that drives rel

229 lla synthesis is a complex and energetically expensive process that is tightly regulated.

230 enic rodent systems that are low-throughput, expensive, prolonged, and do not fully represent other s

231 onventional are Taqman probes, which require expensive quantitative polymerase chain reaction (qPCR)

232 sed in heterogeneous catalysis, but they are expensive, rare and the ability to tailor their structur

233 Conventional HTS platforms require expensive reagents and typically have complex assay form

234 onventional biochemical assays which require expensive reagents, is time-consuming and more often is

235 Expensive regulation of biotech crops is prohibitive for

236 substantially in recent years, despite being expensive, resource intensive, associated with major com

237 sed rabies postexposure prophylaxis (PEP) is expensive, restricting access to life-saving treatment,

238 More recent and expensive rhodium-phosphine catalysts are hundreds of ti

239 oids high-cost system state preparations and expensive running procedures and measurement apparatuses

240 diotherapy therapies without complicated and expensive scanning.

241 However, they are expensive, scarce and heterogeneous.

242 est for AD would be a less invasive and less expensive screening tool than the currently approved cer

243 eiling that does not require computationally expensive simulations or a splitting procedure that redu

244 es without having to perform computationally expensive simulations.

245 applications is that very slow deposition on expensive single-crystal substrates yields high crystall

246 requires quantum installations that are more expensive, slower, and less scalable than classical opti

247 cular exciplex system which usually needs an expensive small molecule such as 2,8-bis(diphenyl-phosph

248 a potential substitute to the ubiquitous and expensive Sn doped In(2)O(3) as a transparent electrode

249 Unfortunately, DAAs remain expensive, so treatment of all HCV-infected patients wou

250 To curate and organize expensive spaceflight experiments conducted aboard space

251 eters that can be used to interpret the less expensive steady-state anisotropy data of candidates.

252 his work is to move beyond the low-error and expensive synthesis employed almost exclusively in today

253 hitectures, which represent a move away from expensive systems optimised for single measurements, tow

254 timate conservation costs, especially at the expensive tail of the distribution.

255 However, the process is expensive, technically challenging, and not readily scal

256 ancer models of a quality comparable to more expensive techniques at a fraction of the cost.

257 Many complex and expensive techniques have been employed to produce PNIPA

258 of mycotoxins usually relies on complex and expensive techniques, the availability of suitable instr

259 physiologies allowing reduced investment in expensive testes.

260 Biochar is 617% more expensive than common fertilizers.

261 r TAVR than SAVR and were significantly more expensive than MT alone.

262 and despite of the factor that RALP is more expensive than ORP.

263 atitis C virus (HCV) antigen testing is less expensive than quantitative reverse-transcription polyme

264 Although it is more expensive than standard CDTI, costs vary depending on th

265 16S PCR is more expensive than targeted PCR, with both assisting in micr

266 The EAT-Lancet diet is also more expensive than the minimum cost of nutrient adequacy, on

267 for-profit system that is substantially more expensive than those of its European counterparts and de

268 ntain than other primary cells, and are less expensive than using an animal model.

269 avoid or reduce the use of more invasive and expensive therapies.

270 nuous renal replacement therapy was the most expensive therapy).

271 rcialization is prevented by impractical and expensive THz instrumentation.

272 This is an expensive, time-consuming process which introduces disco

273 nce impacts functionality often necessitates expensive, time-consuming screens to identify effective

274 ften lead to models that are computationally-expensive to analyse and perform model fitting, and ofte

275 ividually and in combination are limited and expensive to collect.

276 It is time-consuming and expensive to determine experimentally, via trial-and-err

277 the kernel functions become computationally expensive to estimate.

278 New insecticides, however, can be expensive to implement in low-income countries.

279 her cases, staining may be time-consuming or expensive to implement.

280 ypically, these materials are poorly robust, expensive to manufacture, and often too specific for a s

281 autologous T cells, which are difficult and expensive to manufacture.

282 asingly congested, yet traffic data is often expensive to obtain, making informed policy-making harde

283 anufacturing processes make it difficult and expensive to produce emulsion adjuvants on a large scale

284 However, such antibodies can be expensive to produce, challenging to engineer, and are n

285 logies made a huge leap from trendy and very expensive to routinely executed and relatively cheap ass

286 n could be used to improve the difficult and expensive-to-measure phenotypes such as PME.

287 mble approach where one such computationally expensive tool, discrete element method, is combined wit

288 n masks, dangerous chemicals, and additional expensive tools, e.g., a mask writer or bonding machine.

289 estinal disease tolerance is a metabolically expensive trait, whose expression is restricted to therm

290 creation of a framework for computationally expensive transient models has not been fully explored.

291 d current examples are generally mediated by expensive transition metal species.

292 perimentally derived results from the use of expensive Transmission Electron Microscopic images and D

293 in health care costs, given the limited and expensive treatment options for these patients.

294 ectromagnetic motors, which make them heavy, expensive, unsafe near people, and ill-suited for unpred

295 sence of evidence of clinical superiority of expensive versus less costly options, substantial opport

296 Energetically expensive vital functions such as immunological response

297 the drug discovery processes faster and less expensive, we developed binary and continuous Quantitati

298 dulators approved for use to date are highly expensive, which has prompted questions about the afford

299 Existing inverse methods are computationally expensive, which take days to weeks to complete for a si

300 g queried, such tasks can be computationally expensive with a runtime ranging from few minutes up to