ライフサイエンスコーパス: experimental animal model

1 ites complication is hampered by the lack of experimental animal model.

2 anges in differential renal blood flow in an experimental animal model.

3 y counteracted acute lung eosinophilia in an experimental animal model.

4 ), using the conventional Fischer rat as the experimental animal model.

5 severity of aortic regurgitation (AR) in an experimental animal model.

6 ing microembolization to migraine aura in an experimental animal model.

7 rol transport, and prevented liver injury in experimental animal models.

8 genetic mutations, and the complexity of the experimental animal models.

9 erum and many extraintestinal tissues in all experimental animal models.

10 iPFK-2 expression decreases tumor growth in experimental animal models.

11 sial temporal lobe epilepsy in humans and in experimental animal models.

12 s against many carcinogen-induced cancers in experimental animal models.

13 e less virulent than the wild-type strain in experimental animal models.

14 due in large part to the dearth of relevant experimental animal models.

15 is rare in animals and poorly reproduced in experimental animal models.

16 s an important role in insulin resistance in experimental animal models.

17 ing the early stages of infection in several experimental animal models.

18 ponses have destroyed growing tumor cells in experimental animal models.

19 infection have been hindered by the lack of experimental animal models.

20 orodibenzo-p-dioxin and related compounds in experimental animal models.

21 nset is limited by the lack of adjuvant-free experimental animal models.

22 ding to a reduction of local inflammation in experimental animal models.

23 n into the recipient and including data from experimental animal models.

24 tively promoting periodontal regeneration in experimental animal models.

25 is difficult to determine without the use of experimental animal models.

26 leveraging data from both human subjects and experimental animal models.

27 e staphylococcal PSM-associated virulence in experimental animal models.

28 has been hindered by a paucity of tractable experimental animal models.

29 inflammation in both human hypertension and experimental animal models.

30 inflammation in both human hypertension and experimental animal models.

31 dance with several studies done in different experimental animal models.

32 is infection in both humans and unvaccinated experimental animal models.

33 s of CD4(+) regulatory T cells in humans and experimental animal models.

34 iding effective reduction of tumor burden in experimental animal models.

35 ber D (NKG2D) mediates antitumor immunity in experimental animal models.

36 been developed for use in the clinic and in experimental animal models.

37 echanisms greater than that anticipated from experimental animal models.

38 mple of latent viral infection in humans and experimental animal models.

39 regs) to achieve this have been promising in experimental animal models.

40 brain injury and adversely affect outcome in experimental animal models.

41 d DC, and from analyses of their function in experimental animal models.

42 en studied extensively both in humans and in experimental animal models.

43 ions have also been identified in humans and experimental animal models.

44 ment and its disruption in human infants and experimental animal models.

45 tal programming can be modeled in a range of experimental animal models.

46 Thus, in this experimental animal model, a high-titer vaccine-induced

47 In experimental animal models, administration of talactofer

48 ivities of the superantigens, and protect an experimental animal model against shock.

49 al for the treatment of MRSA pneumonia in an experimental animal model and warrants further investiga

50 ting transmission of Borrelia burgdorferi in experimental animal models and are now being tested in h

51 tional abnormalities previously described in experimental animal models and can at least partially ac

52 Analysis of these gene products in experimental animal models and cell systems has led to a

53 Experimental animal models and epidemiological data indi

54 ng in pain conditions.SIGNIFICANCE STATEMENT Experimental animal models and human psychophysical stud

55 ls in inflammation-induced bone loss in both experimental animal models and human rheumatoid arthriti

56 Recent and accumulating work in experimental animal models and humans shows that diet ha

57 g to the changes observed with aging in both experimental animal models and humans.

58 istent critical determinant of PH and PAH in experimental animal models and humans.

59 Drawing from experimental animal models and observational human studi

60 usibility for the link has been supported by experimental animal models and observational studies in

61 stroke pathology has been underestimated in experimental animal models and this may have contributed

62 as been established by cell culture studies, experimental animal models, and clinical trials.

63 sceptibility, the necessity for adjuvants in experimental animal models, and the often paradoxical ef

64 Experimental animal models are indispensable to the fiel

65 However, new experimental animal models are now available that will a

66 Studies in humans and experimental animal models are revealing the genetic and

67 Miniature pigs have been used as an experimental animal model, but they are still large and

68 circulation have been studied extensively in experimental animal models, but have failed to recapitul

69 e a human metabolic disease is induced in an experimental animal model by human hepatocyte transplant

70 malformations have been produced in multiple experimental animal models, by perturbing selected molec

71 Sustained rapid pacing in experimental animal models can produce severe biventricu

72 In experimental animal models, chronic stress leads to neur

73 These ligands were tested in an experimental animal model containing tumors that express

74 Experimental animal models demonstrate that maternal imm

75 In human disease and experimental animal models, depressed Ca(2+) handling in

76 n the foundations of these approaches in new experimental animal models designed to test novel vaccin

77 section evaluates the use of agents given in experimental animal models during or after the onset of

78 Clinical, in-vitro and experimental animal model evidence continues to mount in

79 To review the clinical, in-vitro and experimental animal model evidence for the pathogenicity

80 i establishes long-term infection in various experimental animal models except for New Zealand White

81 These studies describe a novel experimental animal model for examining the spontaneous

82 To create an experimental animal model for HD, transgenic mice were g

83 iniature pigs in the world and is used as an experimental animal model for life science research.

84 ammatory demyelinating disease, providing an experimental animal model for multiple sclerosis.

85 g disease in mice provides a highly relevant experimental animal model for multiple sclerosis.

86 that potentially regulate aging, and present experimental animal models for addressing these question

87 in, DJ-1, PINK-1 and LRRK2) and studies from experimental animal models has provided crucial insights

88 sease, together with earlier studies and new experimental animal models, has provided important and n

89 Several experimental animal models have been developed to study

90 Studies in experimental animal models have demonstrated that chemok

91 ssess or quantify NETosis in vivo, and other experimental animal models have failed to demonstrate a

92 Experimental animal models have identified neuronal conn

93 Several lines of evidence in experimental animal models have indicated the central ro

94 Previous studies in experimental animal models have reported that administra

95 Experimental animal models have shown that inhibition of

96 , explanted and biopsied human material, and experimental animal models, have demonstrated that liver

97 omparing brain function between patients and experimental animal models; however, the relationship be

98 ce from patients with heart failure and from experimental animal models implicates effectors of innat

99 mobilization of human progenitor cells in an experimental animal model in response to different treat

100 rtension-induced renal damage, we derived an experimental animal model in which two genetically diffe

101 alth benefits have been attributed to CLA in experimental animal models including actions to reduce c

102 These findings in humans and in experimental animal models indicate the presence of pote

103 Progressive renal injury in humans and experimental animal models is characterized by tubular a

104 Here we show in experimental animal models (laboratory rats and mice) th

105 Due to the paucity of experimental animal models, little is known about how ho

106 Importantly, in experimental animal models, low dietary potassium intake

107 h Mycobacterium tuberculosis were used in an experimental animal model mimicking active tuberculosis

108 ed neutrophil counts and MPO activity, in an experimental animal model of ALI induced by systemic end

109 ion carbohydrate antigens was studied in the experimental animal model of alpha1,3galactosyltransfera

110 ce induction to the alpha-gal epitope in the experimental animal model of alpha1,3galactosyltransfera

111 Although the experimental animal model of anterior chamber-associated

112 An experimental animal model of atopic dermatitis induced b

113 A reproducible experimental animal model of fulminant hepatic failure (

114 to mediate collagen Ab-induced arthritis, an experimental animal model of immune complex-induced join

115 us CPs in modulating abscess formation in an experimental animal model of intraabdominal infection.

116 This hypothesis was tested in a unique experimental animal model of knockout mice for alpha1,3g

117 An experimental animal model of meningeal leukemia was deve

118 , the EH(ITSN)-KO(ITSN+/-) mouse is a unique experimental animal model of PAH that recapitulates most

119 g gadolinium-labeled peptide, EP-1873, in an experimental animal model of plaque rupture and thrombos

120 ate it as a model of atopic dermatitis, this experimental animal model of pruritic inflammatory skin

121 tabolic acidosis and longer survival in this experimental animal model of septic shock.

122 ified that confer robust cardioprotection in experimental animal models of acute ischemia and reperfu

123 Studies on experimental animal models of AF implicate a reduction i

124 Experimental animal models of AKI demonstrate that renal

125 iting cardiomyocyte apoptosis in 2 different experimental animal models of AMI.

126 he functions of natural killer (NK) cells in experimental animal models of atherosclerosis, it is not

127 pidemiologic studies, with some support from experimental animal models of atherosclerosis.

128 pidemiologic studies, with some support from experimental animal models of atherosclerosis.

129 The most commonly used experimental animal models of CHIKV infection are mice a

130 Different experimental animal models of chronic asthma were used i

131 In experimental animal models of chronic renal injury, such

132 responses are present in cells derived from experimental animal models of diabetes.

133 pigs are capable of restoring euglycemia in experimental animal models of diabetes.

134 Endogenous IL-1Ra is produced in numerous experimental animal models of disease as well as in huma

135 an arthritis susceptibility locus mapped in experimental animal models of disease has been used to i

136 and enhanced neuronal synchrony observed in experimental animal models of epilepsy characterizes hum

137 mechanism of apoptosis in conditions such as experimental animal models of glaucoma and optic nerve t

138 he sympathetic nervous system alterations in experimental animal models of hypertension.

139 and Rhizopus oryzae has been demonstrated in experimental animal models of infection.

140 ded evidence of such processes in humans and experimental animal models of insulin-resistant diabetes

141 rved phenotypic outcomes in both control and experimental animal models of ischemic stroke.

142 Patients with chronic kidney disease and experimental animal models of kidney fibrosis manifest d

143 Immunologic studies involving experimental animal models of L. tropica infection are v

144 linical studies of liver disease and certain experimental animal models of liver injury conspicuously

145 bly through the development of UV-responsive experimental animal models of melanoma.

146 vant to the induction of disease symptoms in experimental animal models of MG, since numerous reports

147 sthenia gravis (MG) in humans, as well as in experimental animal models of MG.

148 omosome 17q, homologous to a locus linked to experimental animal models of multiple sclerosis, has be

149 cularization and pulmonary hypertension in 2 experimental animal models of PAH in vivo Up-regulation

150 view will focus on plexiform arteriopathy in experimental animal models of PAH.

151 genesis of PsA-related dactylitis comes from experimental animal models of PsA-like disease, as well

152 In experimental animal models of sepsis telavancin was show

153 h are poorly understood because of a lack of experimental animal models of sunburn itch.

154 hological activity in epileptic patients and experimental animal models of temporal lobe epilepsy.

155 Experimental animal models of type 1 diabetes mellitus (

156 Several experimental animal models of viral-induced neurodegener

157 ns as well as selected articles dealing with experimental animal models or the chemistry of currently

158 orvegicus, the laboratory rat, a widely used experimental animal model organism.

159 r junction (NMJ) have predominately utilised experimental animals, model organisms, or monolayer cell

160 dvanced, at least in part, due to the use of experimental animal models, particularly the model of ce

161 Genome-wide association studies and experimental animal models point at a central role of th

162 Many fail because experimental animal models poorly predict human xenobiot

163 rally occurring plant estrogen in soy, in an experimental animal model previously reported to result

164 ition of FoxO1 function prevents diabetes in experimental animal models, providing impetus to identif

165 against liver injury and inflammation in an experimental animal model recapitulating features of sev

166 2)P beta-particle-emitting stents in various experimental animal models results in discordant effects

167 t and growth of carcinogen-induced tumors in experimental animal models, results from human studies a

168 This daring conclusion that is based on an experimental animal model should now be confirmed in hum

169 Experimental animal models show changes in the gut micro

170 ence derived from human clinical studies and experimental animal models shows a causal relationship b

171 Currently, few experimental animal models similar to humans are availab

172 is lacking, non-randomized observational and experimental animal model studies were used.

173 Experimental animal models, such as transgenic mice, hav

174 Furthermore, arguments based on experimental animal models suggest a critical role of th

175 Recent studies involving experimental animal models suggest a role of the gut mic

176 Observational human studies and experimental animal models suggest that childhood exposu

177 Previous results from experimental animal models suggest that post-TBI hypergl

178 Experimental animal models suggest that statins may fost

179 Accumulated evidence from experimental animal models suggests that neuronal loss w

180 Experimental animal models support both the antibody and

181 Several published studies have used this experimental animal model system to demonstrate potentia

182 this review we focus on several widely used experimental animal model systems to highlight differenc

183 alpha/beta) antagonist, both in vitro and in experimental animal model systems.

184 apidity and plasticity of viral evolution in experimental animal model systems.

185 es in suppressing tumor cell regrowth in two experimental animal model systems.

186 fects on liver injury and inflammation in an experimental animal model that mimics severe AH in human

187 cause of a shortage of equivalent studies in experimental animal models that permit neural-level insi

188 ome progresses, so does the need for natural experimental animal models that promote a mechanistic un

189 We review the recent clinical trials and experimental animal models that provide evidence in supp

190 In the experimental animal model, the hemodynamic, hematologic,

191 In experimental animal models, these compounds exhibited ex

192 As with all experimental animal models, they are flawed in one way o

193 known to inhibit DA-associated behaviors in experimental animal models through unknown mechanisms.

194 grating patient-based data with results from experimental animal models to gain deeper understanding

195 In this review we focus on experimental animal models to identify quantitative trai

196 Experimental animal models to predict physiological resp

197 -guided focused ultrasound has been shown in experimental animal models to reduce amyloid-B plaque bu

198 that prolongs the survival of allografts in experimental animal models, to potentiate the immunosupp

199 This prompted the development of experimental animal models using controlled maternal cal

200 An experimental animal model was used to assess the importa

201 The development of experimental animal models was deemed essential for the

202 In an experimental animal model, we show that in vitro knockdo

203 mechanisms underlying these events using an experimental animal model, we show that inflammation may

204 comparing these results to previous work in experimental animal models, we found that over 80% of th

205 ic side effects, including weight loss in an experimental animal model, when compared to the free dru

206 of the present study was to determine in an experimental animal model whether CD8 T cells in pig xen

207 mechanistic studies using human samples and experimental animal models, with technological and metho

208 ro, yet there has been no obvious success in experimental animal models, with the notable exception o

209 cilitates studies in platelets obtained from experimental animal models without the need of special d