ライフサイエンスコーパス: explain how

1 This motion also can explain how 5'-dAdo. subsequently forms the organometall

2 we have identified the molecular links that explain how a change in the availability of the diet met

3 These findings explain how a distinctive ubiquitin-like protein alters

4 P signaling in insect antiviral immunity and explain how a family of cGAS-STING evasion enzymes evolv

5 mes more popular and provides a mechanism to explain how a shared vocabulary can spontaneously self-o

6 n and a wealth of standing genetic variation explain how a single member of the biotic community can

7 This helps to explain how A. aegypti can sustain explosive epidemics s

8 activator of RodA both in vitro and in vivo, explaining how a SEDS-bPBP complex can coordinate its du

9 ed at the energetic cost of a G-C base pair, explains how a single 5'-guanosine modifies the function

10 ight on mutant aaRS disease aetiologies, and explains how aaRS sequestration of uncharged tRNAs can p

11 ction of alpha(2)delta-2 identified here may explain how abnormal alpha(2)delta subunit expression ca

12 heir scholarly target article, Gilead et al. explain how abstract mental representations and the pred

13 This study explains how activated NK cells survive in the ROS-rich

14 he expression of AE3 in neurons, which could explain how AE3 reduces seizure susceptibility.

15 propose a model based on kinetic trapping to explain how affinity could affect TJ assembly.

16 Our results explain how affinity-reducing functional groups may lead

17 ensitive, providing a potential mechanism to explain how ageing influences their amplitude and functi

18 It explains how ALT externalization is the combined consequ

19 We explain how alterations to their profiles and functions

20 The model explains how alterations in the level of death receptor-

21 This lipid-dependent Slo1 gating may explain how amphipathic signaling molecules and pharmaco

22 fication of numerous AMPK targets has helped explain how AMPK restores energy homeostasis.

23 Furthermore, the identified mechanism may explain how an altered expression of calcium channel sub

24 to IgE against the native molecule and also explain how anaphylaxis may occur in individuals who lac

25 or syntax may have arisen, it is critical to explain how ancient hominins began to produce vocalizati

26 ing, distracting and misleading-that clearly explain how and why anthropogenic sensory pollutants imp

27 Here, we present a conceptual framework to explain how and why females might evaluate a male's BT b

28 It also helps explain how and why people stray from logic when given d

29 Neighbourhood effects also help explain how and why the benefits of interventions vary b

30 This principle also explains how another (p)ppGpp target GMK is variably reg

31 inciple revealed by this work can be used to explain how any CaM-binding TF decodes calcium signals t

32 nd preference in histone incorporation would explain how asymmetric old and new H3 and H4 are establi

33 tructure of the chloroplast F(1)F(o) complex explains how ATPase activity is turned off at night by a

34 Thus, these results explain how BATF3-dependent Irf8 autoactivation underlie

35 Our simulations explain how bats can hunt successfully in a group despit

36 We specifically explain how biological processes, particularly those occ

37 This model explains how both exonuclease and endonuclease activitie

38 gnaling mediated transcription, which likely explains how both loss of Notch signaling and ectopic ex

39 , the presence of SIZ1 and SUMO in these NBs explains how both the timing and amplitude of the high-t

40 In this issue Ohsaki et al. explain how breastfeeding can prevent the onset of food

41 ential key checkpoint of cambial activities, explaining how cambium-driven growth is altered in respo

42 Additionally, the mechanisms explaining how cancers survive and exit LNs are largely

43 d by a subset of CRISPR-Cas genomic loci and explain how Cas12c/d systems avoid requirements for host

44 Our results explain how Cas4 cleavage coordinates with Cas1-Cas2 int

45 explain how CD226 expression loss on CD8(+) T cells impa

46 These data help explain how CDK activity controls replication initiation

47 r further models of cell-cycle regulation to explain how cell size controls passage through Start.

48 Specifically, using a common framework, we explain how cells characterized by contact inhibition of

49 These results explain how centromere targeting of the CPC in mitosis i

50 their differentiation dynamics, which could explain how changes in ACE2 promoted by SARS-CoV-2 cell

51 They explain how changes in the balance of positive and negat

52 onically nonadiabatic PCET theory is used to explain how changing the driving force for the electron

53 ructures of Ruminococcus gnavus GUS with 2-7 explained how charge, conformation, and substituent of i

54 newly-discovered NSC-BV communication route explains how circulatory neurogenic mediators are 'sense

55 co modeling and in vitro biophysical methods explain how CK1e-specific phosphorylation events control

56 Much ecological research aims to explain how climate impacts biodiversity and ecosystem-l

57 Veissiere et al.'s proposal aims to explain how cognition enables cultural learning, but fai

58 We present a mathematical model to explain how coherent, directional movements could arise

59 th NGD and RQC The studies also structurally explain how collided ribosomes generate a unique interfa

60 atures of this multiplexed mechanism help to explain how complex connectivity is encoded and robustly

61 ir nearest neighbours when shoaling, thereby explaining how conflict over whether private or social i

62 s of scientific inquiry, and detailed models explain how consensus impressions of trustworthiness are

63 hough considerable progress has been made in explaining how conspicuous coloration can be used in fun

64 Here, we explain how contrasting mechanical stimuli arise on a su

65 Therefore, this study explains how corona-MAD1 generates a robust SAC signal,

66 Our structural and biochemical data explain how CP12 integrates responses from both redox st

67 Our data explain how Ct deletions in XLP alleviate autoinhibition

68 These findings at least partially explain how Ct infection could result in adverse pregnan

69 In this review, the authors explain how deep learning works in the context of mammog

70 del provides the first normative theory that explains how dendrites increase the brain's capacity for

71 Our mechanistic model explains how DENV uses the EV pathway to transfer miR-14

72 protein family, are identified that begin to explain how deregulation of miR-135a may contribute to e

73 These findings help explain how development proceeds robustly in the face of

74 We introduce a molecular model explaining how diabetic metabolism possesses important c

75 n coexistence theory is increasingly used to explain how differences between competing species lead t

76 al diversity within the ABC toxin subfamily, explaining how different ABC toxins are capable of recog

77 pare competing trophic cascade hypotheses to explain how dingoes could influence shrub recruitment.

78 Our findings begin to explain how distinct cellular systems rely on a common m

79 These findings help explain how distinct, tunable actin polymerization pathw

80 These results reveal a mechanism explaining how distraction during consumption attenuates

81 tion was first proposed over 30 years ago to explain how diverse G protein-coupled receptors achieve

82 In this Quick Guide, Votier and Sherley explain how diverse seabirds play important roles in eco

83 sembly provides a mechanistic framework that explains how diverse genetic disorders can converge on s

84 The compartment selective action helps explain how dopamine somatic, but not terminally express

85 and that upregulation of Fgf13 may partially explain how E2F1 promotes breast cancer metastasis.

86 Thus, explaining how each Hox protein can selectively control

87 This likely explains how ecosystem-scale whole-forest canopy conduct

88 (TMT) is a generic sociological theory that explains how emergent projects of collective action are

89 Life History Theory, Baumard argues, explains how England's world-supreme affluence psycholog

90 re can modify the skin immune system and may explain how environmental exposures during life, and the

91 osylation-dependent protein sequence editing explains how ER-associated and cytosolic isoforms of SKN

92 g with enzymatic and computational analyses, explain how ERAP1 can select peptides based on length wh

93 We propose a mechanistic model explaining how ERAP1-mediated trimming of MHC I-bound pe

94 In this Perspective we explain how executable computational models meet this ne

95 However, current models explaining how expectations render perception either ver

96 f the amino terminus of ExsD in ExsA binding explains how ExsC might relieve the ExsD-mediated inhibi

97 However, these interactions do not explain how Fim1 is prevented from associating strongly

98 A quantitative statistical model explains how for certain reactions, higher particle dens

99 The mechanism elucidated here helps explain how G(i/o) and G(q/11) co-stimulation induces a

100 We investigate whether exploratory adaption explains how GBM cells from different anatomic regions o

101 challenge that arises in these studies is to explain how genes identified as relevant in the given ex

102 se results thus provide a novel mechanism to explain how global environmental change can generate con

103 These findings help to explain how GPBP contributed to the formation of these e

104 Our findings explain how GTP hydrolysis controls septin assembly, and

105 Collectively, we reveal a mechanism explaining how HDAC11 plasticity promotes breast cancer

106 We thus provide a mechanism that can explain how hierarchy arises in initially egalitarian so

107 The model explains how homologous recombination maintains the cohe

108 anistic models at the psychological level to explain how humans plan, execute, and consolidate skille

109 a Bayesian model of hierarchy discovery that explains how humans discover such useful abstractions.

110 oliferation through exaggerated T cell help, explaining how HVEM loss contributes to GC lymphomagenes

111 obvious electrophysiological mechanism that explains how hyperpolarizing a hub cell results in wides

112 This research explains how increases in cortisol, a biomarker of stres

113 flects characteristic features of human FLs, explaining how indolent tumors arise from GC B cells.

114 lar mRNAs to support antiviral responses and explain how influenza virus uses this same activity to r

115 ker by the chromatin remodeller INO80, which explains how INO80 can define nucleosome-depleted region

116 ds on a constructionist theory of emotion to explain how instances involving diverse physiological an

117 idyltransferase centre (PTC) completion that explains how integration of the last ribosomal proteins

118 These results explain how internal and external protons control intrac

119 ts provide a general conceptual framework to explain how internal signals can be integrated into our

120 Altogether, we propose a simple mechanism explaining how intracellular mechanics enable the cells

121 HF), but there is a lack of mechanistic data explaining how iron could augment exercise performance d

122 cular structure of the FA core complex would explain how it acts to maintain genome stability.

123 channels and suggest a mechanistic basis to explain how K2P channels are modulated by VAs.

124 The model also naturally explains how KaiA, by acting as a nucleotide exchange fa

125 ard a focus on network and circuit models to explain how key nodes in the limbic system and beyond in

126 e same type of infection, it is essential to explain how key processes, such as host responses to inf

127 These results explain how L1 can evade repression and retrotranspose i

128 This deformation could explain how lateral membrane tension can be converted in

129 This cascade of events offers a mechanism to explain how local tissue inflammation and vascular perme

130 Our data suggest a unifying model to explain how loss of OCRL results in tubular proteinuria

131 5 antagonizes MYC and provide a mechanism to explain how loss of SNF5 can drive malignancy.

132 This explains how many animals and robots may grasp complex s

133 This helps to explain how mass cell suicide can evolve, as any small b

134 urrent study provides a mechanistic basis to explain how matrix controls the antifungal effector func

135 Our analysis explains how mechanical force applied to alphaE-catenin

136 nism also ensures spatial regulation of Tfp, explaining how MglA switching provokes directional rever

137 Collectively, we derive a molecular model to explain how Microprocessor recognizes a pri-miRNA and ac

138 er microtubule nucleation pathways and helps explain how microtubules are generated in the spindle.

139 ct vertical air movements and this mechanism explains how migrants are retained in the jet for long p

140 Discoveries reported by Hondele et al. explain how mRNA molecules can be passed from one puncta

141 It helps explain how multiscale cooperation from the community to

142 Balance theory explains how network structural configurations relate to

143 directly affect motor performance and might explain how neural repetition effects lead to improvemen

144 However, a molecular-scale mechanism that explains how neurons appropriately balance these two mic

145 Our structures explain how Nme1Cas9 and Nme2Cas9 read distinct PAM sequ

146 tracellular O(2) concentration may therefore explain how non-heterocyst-forming cyanobacterial diazot

147 ings are noteworthy because they may in part explain how obesity drives colon cancer progression.

148 RagC show the mechanism for this locking and explain how oncogenic hotspot mutations disrupt this pro

149 The findings explain how oncogenic mutants can counteract inhibitory

150 es the 'Minute' phenotype in fruit flies can explain how organisms are able to eliminate the mutant c

151 We explain how our null model controlled for age structure

152 sed by IL-6 and TNF-alpha levels) may partly explain how PA protects against dementia/CIND and mortal

153 We develop a mathematical model that explains how particle shape impacts the relevant electro

154 based model of value coding and gain control explains how particular neuronal constraints on informat

155 The structure of TcPINK1 explains how PD-linked mutations that lie within the kin

156 Our model was also able to explain how people's predictions varied as a function of

157 broadly, this model provides a mechanism for explaining how people condense general physical knowledg

158 approach reproduce the spectroscopy data and explain how periodic microstructures play a critical rol

159 tions for immune regulation, the results may explain how persistent activation of self-reactive B cel

160 These results further biochemically explain how phosphate availability determines a switch t

161 dynamics of phosphoinositides and the other explaining how phosphatidylinositol 4,5-bisphosphate (PI

162 positively charged side chains in RPN13 that explain how phosphorylation increases binding affinity w

163 Flamholz and Shih explain how photosynthetic organisms on earth have evolv

164 se results reveal an endogenous mechanism to explain how physical exercise leads to the induction of

165 ple model of molecular-genetic mechanisms to explain how physiological events taking place immediatel

166 The observations explain how PI3KC3 inhibition by Rubicon, activation by

167 The results explain how point mutations expand the activity spectrum

168 hene, a microscopic model is introduced that explains how point defects determine sensitivity.

169 These structures explain how polymerization increases the fluorescence 20

170 Our results explain how pre-existing paranoia may be the result of a

171 We reveal a novel mechanism that explains how preparatory activity can evolve in motor-re

172 Finally, this electrostatic control explains how protein crowding is spontaneously maintaine

173 branes, our results address the challenge of explaining how proteins could have become colocalized wi

174 Our mathematical model explained how PRP would increase macular blood flow.

175 worm target has been identified that readily explains how PZQ paralyzes and damages schistosomes.

176 concert to control actin dynamics, and help explain how rapid actin network depolymerization is achi

177 I also explain how rationalism can capture insights purportedly

178 We explain how recent advances in artificial intelligence (

179 fer complementary lines of interpretation to explain how recollection and familiarity in Alzheimer's

180 Collectively, these findings help explain how reduced SIRT1 expression, by disrupting lyso

181 uplex unwinding by replicative helicases and explains how replisome components that interact with the

182 Together, our work explains how Retro-2 prevents retrograde trafficking of

183 These observations explain how reversible formation of labile polymers by t

184 ; Gunturkun sufficient, but not necessary to explain how reward uncertainty promotes reward seeking a

185 early indicate a more complex mechanism that explains how RGMs can act as a functionality-changing sw

186 Collectively, our results explain how RIPK4 and IRF6 function to ensure the integr

187 RC2.2 bind RNA, providing a unified model to explain how RNA and allosteric stimuli antagonistically

188 The goal of this study is to explain how RNA can remain soluble and available for int

189 These nonlinear relationships explain how sampling bias from different ends of the non

190 verts towards homeostasis, a constraint that explains how selection operates in normal-appearing epit

191 This model explains how simple cell-intrinsic rules lead to robust

192 and post-GTP hydrolysis state of RagC, which explain how SLC38A9 destabilizes the LFC and so promotes

193 icotine reward-related behavior and may help explain how smokers of menthol cigarettes exhibit reduce

194 ory role of NRP1 as MET coreceptor, and they explain how some snake venoms induce SIRS-like condition

195 Finally, we explain how spatial assortment can be efficiently calcul

196 ontrasting hypotheses have been suggested to explain how species interactions could influence diversi

197 Explaining how species with disparate growth rates can c

198 We applied machine learning to explain how specific interactions controlled the promote

199 semble the eye in vivo These results help to explain how stem cell aggregates spontaneously self-orga

200 cross disparate but linked brain regions may explain how stereotyped patterns of neurodegeneration ar

201 Explaining how structural features of these polymers cha

202 cells, no existing quantitative model fully explains how structural differences between kinesins alt

203 We explain how studies of related individuals such as sibli

204 The discovery of this pathway may explain how subjects harboring ALDH2 rs671 are at a grea

205 rmational changes induced by leukotriene C4, explaining how substrate binding primes the transporter

206 We explain how subtle structural differences, mostly depend

207 This gradual activation mechanism may also explain how SYK maintains ligand-independent tonic signa

208 in cool conditions, providing a mechanism to explain how temperature regulates DOG1 expression.

209 Here we try to explain how that review moved the field forward, and sum

210 sm." I place May's book in the literature by explaining how that assumption is resisted by Christine

211 Our models explain how the activation of pyramidal cells or PV(+) c

212 These data provide a mechanism to explain how the bacteria regulate translation of LLO to

213 Prebiotic chemistry aims to explain how the biochemistry of life as we know it came

214 They help to explain how the brain copes with its capacity limitation

215 Elucidating the neural mechanisms that explain how the brain processes conceptual information i

216 he reversible discharge/charge processes and explain how the carbon interface with Li(2) CO(3) provid

217 Our structures explain how the central domain of CENP-C achieves its hi

218 Together, these experiments explain how the combined action of the two main cell wal

219 Our results provide a molecular model to explain how the conformational dynamics of cpSRP43 enabl

220 es (302 neurons), the design principles that explain how the connectome structure determines its func

221 The computations further explain how the hydrazide catalyst lowers the free-energ

222 Our findings explain how the inner-membrane transport complex control

223 Here, we explain how the key redox chemistry underlying metabolis

224 These findings may explain how the loss of Tango1 can influence Golgi/ER mo

225 corporating these overlapping mechanisms, to explain how the nodes of Ranvier are assembled in both t

226 rom the interior of TADs, these observations explain how the orientation of CTCF binding sites transl

227 Here, we explain how the ppH protocol quantifies the endocytic ac

228 This unanticipated role of Ctp1 might help explain how the processing of DNA ends is coordinated to

229 ights from computational models of memory to explain how the stream of thought flows through the land

230 Our data and model explain how the two domains are organized as an intermol

231 rests of insurers and research subjects, and explain how the United States might learn from them.

232 a are sources of reactivating virus, helping explain how the virus causes lifelong recurrent disease.

233 tal structures and biochemical data have not explained how the second strand is cut to complete the d

234 r argument for representational diversity by explaining how the elements in our ontology are all requ

235 hanism of substrate-assisted product release explains how the BAM complex can stably associate with t

236 of events provides a cellular mechanism that explains how the characteristic crescent-shaped, asymmet

237 referred orientations is demonstrated, which explains how the conversion reaction occurs in alpha-MnO

238 ubstrate for the nuclear ESCRT machinery and explains how the dynamic tethering of chromosomes to the

239 f the aperture shape and size, and our study explains how the features of the mechanical design of ap

240 The structure explains how the geometrically different molecules L- an

241 The work further explains how the infrared spectra associated with this o

242 we sketch out an integrative NPE model that explains how the interactions of psychoeconomic componen

243 and membrane tubulation in ciliogenesis and explains how the intracellular cilium emerges from the c

244 al article by Wertheimer in 1923, the theory explains how the mind groups similar images and fills in

245 lution structure of the hC3Nb3-C345c complex explains how the nanobody blocks proconvertase assembly.

246 It explains how the particular military, logistic, and geog

247 The model explains how the rhythm and amplitude of respiratory osc

248 It explains how the subunits interact with each other and h

249 election models of B-1a cell development and explain how these cells acquire their unique properties.

250 g an 'imperfect' photon counting machine, we explain how these constraints give rise to adaptive quan

251 ry for proper envelope assembly, and we also explain how these enzymes are protected from oxidative i

252 o binding and in vivo cell localization data explain how these features create a pH-dependent retriev

253 t-risk profile of antithrombotic therapy and explain how these findings are changing our approach to

254 al possible mechanisms have been proposed to explain how these multiple tumour-infiltrating cell type

255 ll-mediated attack on the orexin neurons and explain how these new perspectives can inform better the

256 To explain how these problems develop, the neuroimmune netw

257 Here, we explain how these remarkable birds can help us uncover t

258 We explain how these shifts have enabled unscrupulous actor

259 ensive investigation has revealed mechanisms explaining how these patterns are generated, with less b

260 ere, we present a theoretical framework that explains how these larger fluctuations in archaeal cell

261 The text explains how these two possibilities are compatible with

262 I refer to them as event memories and explain how they are different from episodic memory and

263 emerged: 1) taking responsibility-relatives explain how they endorse decisional responsibility but d

264 stress and the psychological mechanisms that explain how they function.

265 lly, there is so far no comprehensive theory explaining how they emerge from the microscopic dynamics

266 view of replication-coupled repair pathways, explaining how they fix polymerase mistakes, respond to

267 l walls was the first proposed hypothesis to explain how this element reduced the severity of plant d

268 rk, based on the physics of shell growth, to explain how this interlocking pattern is created and reg

269 In this essay, we explain how this new theory, the tissue organization fie

270 n A. thaliana Mathematical modeling helps to explain how this nonintuitive behavior can be explained

271 a (modest) increase in excitability, but we explain how this pattern can reverse if a hyperpolarizin

272 flipping, and melting by RAG1 methionine 848 explain how this residue activates transposition, how RA

273 phenotypic changes caused by model honey, we explained how this can be bactericidal even though the a

274 L neurons, and develop a circuit-level model explaining how this may be achieved.

275 Smc5-Smc6 require the Nse5-Nse6 heterodimer, explaining how this nonessential cofactor critically sup

276 e possible cellular and molecular mechanisms explaining how this therapy provides unique benefit to p

277 Here, we identified a mechanism to explain how TIE2 signaling is attenuated in diabetic ani

278 ers into higher-order oligomers, potentially explaining how Tie2 is differentially clustered followin

279 These results can help to explain how to adapt high-altitude for men and women, re

280 the tally of deaths by each approach, and to explain how to interpret the results.

281 nd links to a series of tutorial videos that explain how to prepare model and data files, and how to

282 and multiple loci tracked simultaneously and explain how to quantify and describe chromatin motion us

283 rategies for activating the inflammasome and explain how to subsequently assess multiple downstream e

284 e ERB-based CR tone alignment strategies and explain how to use the ERB-based model in experiments, c

285 hen we provide a tutorial with examples that explains how to apply the UWHAM program package to analy

286 This protocol explains how to use MAGeCKFlute to perform quality contr

287 ition of PtdIns5P by the VHS domain that may explain how Tom1, when in a different VHS domain conform

288 We describe a model to explain how TRAIP performs these disparate functions and

289 d torpedo models have been used for 30 yr to explain how transcription terminates on protein-coding g

290 Can other models explain how TRF2 mediates end protection?

291 The structures explain how tRNA(Ala) is selected via anticodon reading

292 Here, we report on a mechanism that explains how ubiquitination stimulates adaptor function

293 Our structure explains how up-stream effectors, including DOCK2 and EL

294 anistically important phenomena, and also by explaining how variability manifests across different le

295 Current models fail to explain how virus-infected cells rapidly appear within t

296 In this paper, we explain how we achieved the independent layers of intera

297 In this Review, we first explain how we developed the human beta cell lines and w

298 oes not require preexisting actin filaments, explaining how Wsp1 contributes to actin network initiat

299 Cooperative motives do not explain how young children reject unfairness, and assert

300 ndent and -dependent mechanisms converges to explain how young cowbirds emerge from another species'