ライフサイエンスコーパス: expression

1 play a significant role in regulation of PRF expression.

2 atin play important roles in regulating gene expression.

3 st-transcriptional steps of chloroplast gene expression.

4 ce was associated with enhanced Adora2b gene expression.

5 , and direct multiplexed measurement of gene expression.

6 in increased 5-hmC levels and reduced nestin expression.

7 nduce itching in a manner dependent on IL-31 expression.

8 ent as a novel regulatory framework for gene expression.

9 ensus molecular subtypes (CMS1-4) using gene expression.

10 lin and phosphorylated nuclear factor-kappaB expression.

11 observed a striking enhancement in HIF2alpha expression.

12 controlled at the level of IgHC and not IgHR expression.

13 ing between ENaC gamma-subunit and claudin-8 expression.

14 5RO-/lo, CD62L(-), CD27lo) with higher T-bet expression.

15 e E class MADS-box TF GRCD5 activates GhCYC3 expression.

16 e roles of these decay pathways in KSHV gene expression.

17 to bypass Complex I in cells with poor NQO1 expression.

18 h the level of synaptic function and protein expression.

19 king, including genome organization and gene expression.

20 nd is accompanied by dynamic changes in gene expression(1), but the gene regulatory network that cont

21 viduals who are more authentic in their self-expression also report greater Life Satisfaction.

22 Subsequent differential expression analyses based on datasets integrated from di

23 Gene expression analyses of these plants reveal a trade-off b

24 espirometry, enzyme activity assays and gene expression analyses.

25 ves accuracy and sensitivity of differential expression analysis and reduces batch effect compared wi

26 Gene expression analysis indicated VCP expression was particu

27 uencing experiments followed by differential expression analysis is a widely used approach for detect

28 tify the features in downstream differential expression analysis with high accuracy when applied to t

29 Through a combination of proteomics and gene expression analysis, we identify enzymes involved in car

30 e basal program, and simultaneously promoted expression and activation of estrogen receptor (ESR1/ER)

31 The expression and activity of deubiquitinases are critical

32 F(2)-isoprostanes, NOX2, and PKC-alpha/delta expression and atrial fibrosis were significantly increa

33 ate plant salt tolerance by repressing GALS1 expression and beta-1,4-galactan accumulation.

34 tandem repeats that are associated with gene expression and human traits.

35 in the regulation of RSC proliferation, gene expression and in the repression of endogenous retroelem

36 23 and IL-1beta stimulation upregulates LAT1 expression and induces mTOR activation in IL-17(+) gamma

37 The mutation did not affect surface expression and ligand binding but changed the susceptibi

38 at permissive epigenetic regulation of cldn5 expression and low endothelium expression of repressive

39 edge on molecular relationships between gene expression and minerals.

40 zed the deposition of CENH3 in maize by over-expression and mutational analysis.

41 sma membrane to modulate BDNF-dependent gene expression and neuronal dendritic growth mediated by the

42 GLS2 expression and nuclear accrual notably increased by trea

43 dies have shown that the integration of gene expression and protein interaction data improves the rob

44 We also aimed to identify changes in expression and subcellular distribution of proteins invo

45 and carfilzomib in their regulation of OAT1 expression and transport activity.

46 ting that humans synchronize these nonverbal expressions and the physiological mechanisms underlying

47 d markers accompanied by MCM, elevated MUC5B expression, and airway mucus obstruction.

48 pressed erythropoiesis, decreased hemoglobin expression, and caused anemia.

49 amine and glutamate transporter activity and expression, and propose the mammalian target of rapamyci

50 d to determine the levels of MPC-1 and KDM5A expression, and their relationship with the clinicopatho

51 Mitochondrial metabolism and gene expression are highly regulated to accommodate these env

52 tative trait loci (eQTL) and allele-specific expression (ASE) signals.

53 te sample, we investigated the neuronal gene expression associated with CUD by using RNA sequencing o

54 In particular, the levels of antigen expression at the cell surface may determine antibody-me

55 es HIV-1-driven aberrant cancer-related gene expression at the integration site.

56 We also show that H19 regulates TET1 expression at the posttranscriptional level.

57 g a machine learning approach, we built gene expression-based models to predict drug sensitivity for

58 , which lead to the improved downstream gene expression-based prediction of disease outcome.

59 iopsies, while our two late DUX4 target gene expression biomarkers associate with macroscopic inflamm

60 f these variants cause complete loss of NHE6 expression, but how subtler missense substitutions or no

61 nsitive CDK12 reduces DNA damage repair gene expression, but selective inhibition of endogenous CDK12

62 (H3K27me3) are linked to repression of gene expression, but the functions of repressive histone meth

63 een extensively linked to regulation of gene expression, but the mechanisms behind this directed move

64 s demonstrate that holo-WhiB1 regulates gene expression by a non-canonical mechanism relative to well

65 e CTK complex is negative regulator of cat-3 expression by affecting its chromatin structure.

66 In vitro restoration of TET expression by ascorbic acid was accomplished in cultured

67 Notably, constitutive CCL5 expression by CD8(+)T(M) serves as a unique functional i

68 e lengthening of telomeres (ALT)], TERT mRNA expression by RNA-sequencing, whole-genome/exome sequenc

69 Stochastic pulsing of gene expression can generate phenotypic diversity in a geneti

70 express abundant Kindlin-2 and deleting its expression causes severe diabetes-like phenotypes withou

71 issue from eye bank donors to probe how gene expression changes precede disease; and (iii) The affect

72 r integrity, migration, and genome-wide gene expression changes were examined in 16HBE14o- single col

73 Although LeuRS-I was not essential, its expression clearly supported optimal S. islandicus growt

74 We find that high-expression clones carry insertions that are not correlat

75 in-dependent ubiquitylation under endogenous expression conditions.

76 We hypothesize that elafin expression correlates with diabetes.

77 In addition, we found that HUNK expression correlates with overall survival and distant

78 tion analysis to identify loci at which gene expression could potentially explain breast cancer risk

79 a broad physiological range, AID and Blimp1 expression, CSR, somatic hypermutation and plasma cell d

80 d in differential changes of core clock gene expression, demonstrating an exercise and clock interact

81 ous studies examining how CodY controls gene expression directly or indirectly, virtually nothing is

82 by gene-family diversification and homoeolog expression divergence among polyploid lineages.

83 nome-wide measures of mRNA expression, miRNA expression, DNA methylation, and histone acetylation fro

84 has investigated genome-wide changes in gene expression during the normal physiological fasting-feedi

85 expressed in the esophageal gland with high expression during the parasitic stages of nematode devel

86 accuracy, precision, and reliability of gene expression estimation, which lead to the improved downst

87 olecular mechanisms and determinants of gene expression evolution in natural populations, we analyzed

88 on molecular changes in cancer-specific gene expression facilitates efficient targeted therapies and

89 shown to be associated with decreased Cox-2 expression, followed by a decrease in PGE(2) production

90 oss of the ZmNLP5 function led to changes in expression for a significant number of genes involved in

91 explore the application of generalized rate expressions for the prediction of optimal binding energi

92 CD29 also marked T cells with cytotoxic gene expression from different tissues in single-cell RNA-seq

93 This data was integrated with gene expression from E2F2 knockout tumors in an MMTV-Neu back

94 Cardiac sodium channel expression, I(Na) and atrial action potential duration w

95 tly lower frequencies of inhibitory receptor expression, i.e., PD-1 and coexpression of PD-1 and TIGI

96 erleukin-23 treatment on SB and colonic ACE2 expression in 3 clinical trials.

97 s to transcript diversity and modulates gene expression in a dynamic, cell type-specific manner.

98 resolve advanced autoimmunity, with Brg1 re-expression in a minor fraction of Treg cells sufficient

99 Conclusion: ITPR3 expression in cholangiocytes becomes enhanced in CCA.

100 These results suggest that KDM6 expression in DC enhances proinflammatory innate cytokin

101 s, we performed targeted silencing of CYP2J2 expression in human adult ventricular cardiomyocytes and

102 a novel regulator of fetal gamma-globin gene expression in human cells by repressing BCL11A transcrip

103 tely reversed elevated pro-inflammatory gene expression in macrophages.

104 Meanwhile, the intervention of TRAF6 expression in melanoma cells affected the activation of

105 A majority of the identified genes showed expression in migrating NC.

106 e boundary deletions resulted in a change in expression in nearby genes of more than twofold.

107 fibroblast growth factor receptor 1 (FGFR1) expression in NSCLC cell lines H1975, HCC827, and YLR086

108 tigate the mechanisms that regulate AXL over-expression in pancreatic ductal adenocarcinoma (PDAC).

109 nduces downregulation of neuregulin-1 (NRG1) expression in parvalbumin-expressing (PV) inhibitory neu

110 trated that these LTR12C elements drive gene expression in primary CD4+ T cells.

111 y of soy PG to inhibit inflammatory mediator expression in response to activators of the pattern reco

112 In addition, high miR-1260b expression in serum was correlated with radiological tai

113 accinia virus that introduces truncated CD19 expression in solid tumors, which are then eradicated by

114 als an unexpected isoform diversity of MYO7A expression in the cochlea and highlights MYO7A's essenti

115 , and environmental stressors shut off TRA-1 expression in the entire non-gonadal soma, suggesting th

116 , a food signal is required to turn on TRA-1 expression in the intestine, and environmental stressors

117 Moreover, we found the intensity of mRNA expression in the liver correlated with the pKa of DLNPs

118 t leads to a reprogramming of circadian gene expression in the liver in analogy to what is observed i

119 nhanced MeCP2 SUMOylation and increased Wnt6 expression in these animals by EE.

120 NA sequencing analysis revealed altered gene expression in Tph1 deficient ILC2s including inducible T

121 STAT1 expression in WAT inversely correlated with fasting plas

122 We observed widespread gene expression in, central and peripheral nervous system, li

123 wn-regulated as cellular demand for antibody expression increased in CHO cells during the production

124 reased mitochondrial area, complex III and V expression increased in debanding compared with sham or

125 Both macrophage number and Vegf-A expression increased in end target muscles after nerve i

126 mental trajectories of leaf allometry, whose expression is contingent heavily upon the environment.

127 to nucleosomes during the S phase when their expression is highly upregulated.

128 es, knowledge of mechanisms that induce gene expression is limited.

129 While caspase-8 expression is lost in some tumors, it is increased in ot

130 Our results show that the Pax6 expression is maintained in the adult brain of lungfishe

131 duration were reduced and potassium channel expression (Kv1.5) and current (I(Kur)) and F(2)-isopros

132 Interference with U3 snoRNA expression led to reduction of rRNA levels and translati

133 cted with T. gondii, as associated with high expression level (P <= 0.001) of Peak # 15 (2 x Neu5Gc)

134 35,458 cases, n = 344,901 controls) and gene expression levels from 21 tissue datasets (brain; blood;

135 (UM, USC, and KCCRI) were used to assess the expression levels of ER-associated proteins using immuno

136 Additionally, expression levels of eukaryotic translation initiation f

137 Expression levels of HLA-F and -G were correlated with t

138 lso revealed significant alterations in gene expression levels of key enzymatic regulators of biochem

139 ccessions of Solanum pennellii revealed that expression levels of known and novel candidate genes (pu

140 H)(2)-D(3) was independent of maturation and expression levels of microRNA-155 and PU.1 (as upstream

141 ses identified multiple SNPs associated with expression levels of post-GPI attachment to proteins 3,

142 many cancer types have been linked with the expression levels of several of these architectural prot

143 The mRNA expression levels of ST6GAL-I and SOX9 in human gastric

144 n resulted in a timely abrogation of miR-223 expression, likely due to activation of E2F1, a known re

145 Genes showing significant differential expression (log2FC >= 1, Padj <= 0.05) were used for dow

146 Decreased lung CYP2A expression may alter smoking-related lung cancer risk an

147 e, we integrate genome-wide measures of mRNA expression, miRNA expression, DNA methylation, and histo

148 d baseline tumor biopsies positive for PD-L1 expression (n = 28/40 evaluable), and response rates wer

149 The control of gene expression noise is important for improving drug treatme

150 ously demonstrated that a sharp drop in Tie2 expression observed across various murine models of crit

151 MicroRNA expression obtained before and after ozone exposure was

152 sites, methylation of 42 is associated with expression of 28 adjacent genes.

153 We also describe the expression of a functional vitamin D receptor in IDEC.

154 Here, we show that expression of a fusion protein combining wheat GROWTH-RE

155 rexpressing hepatoma cells showed high level expression of active beta-catenin, alpha-fetoprotein, an

156 oxidation of fatty acids and stimulated gene expression of acyl-CoA dehydrogenases in the liver.

157 Additional ectopic expression of an engineered glycosyltransferase, "bump-a

158 anscripts, whereas they only weakly affected expression of an exon-exon junction that tags the majori

159 Second, we find that over-expression of an upstream or downstream gene by a fusion

160 However, the function of NE in expression of aversively-conditioned responses has not b

161 wth and induced apoptosis and also increased expression of Bax as well as cleaved caspase-3 and -PARP

162 how with a reversible knockout model that re-expression of Brg1, in conjunction with the severe endog

163 ilized the deacetylase, leading to increased expression of c-Myc, which in turn stimulated a patholog

164 p had tubular cell apoptosis associated with expression of caspase-8, TNFR1, and increased serum TNF-

165 m cell (SC) in the gastric antrum, marked by expression of Cck2r (a GPCR) and Delta-like ligand 1 (DL

166 d with a lentiviral vector inducing constant expression of CD28 accelerated the rejection of allogene

167 in silencing transposons and to regulate the expression of CG/CHG-depleted transposons.

168 that GluN2B-containing NMDARs also regulate expression of cocaine seeking on AD30.

169 e NAc of helpless mice, we found that higher expression of CRY is associated with decreased activatio

170 t LC projections to CeA are critical for the expression of defensive responses elicited by conditione

171 olycomb repressive complex 2 (PRC2) silences expression of developmental transcription factors in plu

172 f MDSC-like cells activated STAT3, increased expression of DNMT1 and DNMT3b, and enhanced survival.

173 and recycling endosomes are disrupted by the expression of dominant-negative mutants of Rab5 and Rab1

174 ion was identified that was characterized by expression of FcgammaRIIIA (CD16) and by high levels of

175 The diversity and near universal expression of G protein-coupled receptors (GPCR) reflect

176 function, we generated mice with zG-specific expression of GCaMP3 and imaged zG cells within their na

177 Our results show that expression of gpTfR1 or hTfR1 comparably enhances JUNV v

178 triction factor that targets and reduces the expression of HIV Env.

179 combining Rag1 and Il2rg deficiency with the expression of human signal regulatory protein alpha, a n

180 R-seq), a method to sensitively quantify the expression of hundreds of chosen genes in single cells.

181 e is associated with the condition-dependent expression of immune function and stress response.

182 g TGF-beta signaling decreased tECM-mediated expression of integrin alpha1, alpha2, and beta1 in hASC

183 that KSHV uses PPD to fine-tune the temporal expression of its genes by preventing their premature ac

184 (GM-CSF) signalling in astrocytes drives the expression of MAFG and MAT2alpha and pro-inflammatory tr

185 accompanied by a pronounced decrease in the expression of many of the key genes required for intrace

186 RNA-Seq profiling shows differential expression of many transcription factors in response to

187 not change TSH levels, weight, histology, or expression of marker genes of the thyroid gland.

188 ation of CRSwNP epithelium due to an altered expression of microRNAs.

189 RNT transcriptional complex is necessary for expression of MMP1 in OFs.

190 ined mechanisms, CovR/S and RocA repress the expression of more than a dozen immunomodulatory virulen

191 Although expression of netrin-1 and DCC is maintained in the adul

192 The levels of expression of nuclear-encoded, TIM23-transported mitocho

193 s, we developed mouse models for regulatable expression of NUP98/NSD1, NUP98/JARID1A, and NUP98/DDX10

194 mmunohistochemistry we find evidence for the expression of opsins and phototransduction genes known t

195 Expression of p.T224M KCNQ1 in Chinese hamster ovary cel

196 R3(injury) displayed increased expression of parenchymal injury transcripts (eg, hypoxi

197 ated with reduced mitotic activity and lower expression of PLETHORA 1 (PLT1)/PLT2 in the RAM.

198 lement-binding protein (CREB) to enhance the expression of proteins essential for long-term synaptic

199 ling achieves this in part by increasing the expression of proto-oncogenes such as MYC and cyclins.

200 different sources differed substantially in expression of proximal tubule markers.

201 Hi-C was performed on ROs, and differential expression of regional genes and a retinal enhancer RNA

202 tion of cldn5 expression and low endothelium expression of repressive cldn5-related transcription fac

203 Regulatory elements drive the cortical expression of SCR, and stele-expressed SHR protein accum

204 no acid cysteine and that gigC regulates the expression of several genes involved in the sulfur assim

205 netic risk variants strongly associated with expression of SNX19 transcript features that tag multipl

206 Changes in expression of some microRNAs, including miR-17, miR-150,

207 Furthermore, macrophages have low/no basal expression of ST2.

208 e, indicating that increased epithelial cell expression of ST6Gal-I is associated with premalignant p

209 ucoinflammatory features, including elevated expression of Th2-associated markers accompanied by MCM,

210 Lentiviral vector-induced re-expression of the beta4 subunit into either the MHb or I

211 account for DNMDP sensitivity, we found that expression of the catalytic domain of PDE3A in cancer ce

212 ved dimethylated H3K9 (H3K9me2) silenced the expression of the Hippo pathway kinase LATS2, and this e

213 red to controls and the kidneys have reduced expression of the hypoxia-inducible erythropoietin mRNA.

214 sitive feed-forward loop involving increased expression of the IL-2 receptor alpha-subunit and activa

215 antly higher autoantibody titers and altered expression of the immune system, autophagy, and apoptosi

216 hanisms by which an MHC-II SE contributes to expression of the locus and suggest how variation in the

217 he presumably protective HFD-induced hepatic expression of the metabolic regulator fibroblast growth

218 Of note, the expression of the recently characterized, immune-inducib

219 We recently demonstrated that increased expression of the stress response protein regulated in d

220 n of osa and brahma was shown to enhance the expression of the Toll pathway-mediated antimicrobial pe

221 ave implications for tissue or cell-specific expression of the virus.

222 Expression of these chimeras under the control of the en

223 The regulation of the expression of these genes is ablated by p63 small interf

224 mics confirms transposon-mediated effects on expression of these genes.

225 gene enhancer CNS2, necessary for indelible expression of this critical transcription factor.

226 rom IPF and control subjects, we showed that expression of TOLLIP gene in the lung parenchyma is glob

227 reg cells in food allergy (FA) had decreased expression of transforming growth factor beta 1 (TGF-bet

228 m effectors reveals that Nfatc1 promotes the expression of twist1b-a well-known regulator of epitheli

229 s and translational capacity, whilst induced expression of U3 snoRNA was accompanied by increased 18S

230 locked ATP and IL-33 release by lowering the expression of VDAC-1 in the plasma membrane.

231 ed SARS-CoV-2 potential tropism by surveying expression of viral entry-associated genes in single-cel

232 Expression of xbp-1s in just two pairs of neurons that s

233 problem with such mouse models is that bnAb expression often hinders B cell development.

234 TLR2 expression on CD14 + + classical monocytes isolated in a

235 AnxA8 gene expression, on the other hand, remained unaltered upon m

236 germline variants that alter the structure, expression, or function of protein-coding regions of can

237 TX infusion time (P = 1.5 x 10-3), FPGS mRNA expression (P = 2.1 x 10-3), and MTX systemic clearance

238 In blood, postnatal miR-218 expression parallels changes occurring in the mPFC.

239 wn-regulated in RCC and shows a differential expression pattern for two isoforms of 36 and 33 kDa.

240 icles have not been examined for a circadian expression pattern.

241 nation of mRNA transcript abundance and gene expression patterns in the internal organs of deceased h

242 the mouse brain cell types implicated by the expression patterns of associated genes.

243 ion of organ shape is fueled by variation in expression patterns of regulatory genes causing changes

244 Recent work has shown that gene-expression patterns within the mTEC compartment are hete

245 cell types by analyzing ligand and receptor expression patterns.

246 Small RNAs (sRNAs) regulate gene expression, play important roles in epigenetic pathways,

247 protein functions involves differential gene expressions, post-translation modifications, and signali

248 e state, indicating that they are poised for expression prior to the initiation of pluripotency trans

249 However, a rescue in the expression profile of pluripotency factors was not obtai

250 A specific gene expression profile, referred to as ECM3 (Extracellular M

251 examined social status-dependent brain gene expression profiles across vertebrates, yet social statu

252 We hypothesized that variants with similar expression profiles may be the product of biological noi

253 Here, we tested the hypothesis that gene expression profiles of protein-coding genes expressed in

254 al understanding by associating SN cell type expression profiles with specific disease risk.

255 l effector molecule through single-cell gene expression profiling.

256 Genotype-Tissue Expression Project (GTEx) RNA-seq data were used to cons

257 ions, both of which are associated with mRNA expression QTLs.

258 limit the explanatory power of brain-related expression quantitative trait loci (eQTL) and allele-spe

259 Expression quantitative trait loci analyses identified m

260 recipitation sequencing, RNA sequencing, and expression quantitative trait loci data.Measurements and

261 nd MCT 1 (R = 0.85, P = 0.032) and HIF1alpha expression (R = 0.83, P = 0.043).

262 Furthermore, FICZ-induced MMP1 expression required both AHR and ARNT, demonstrating tha

263 9 to delete MafK-int6 binding region in IRF8 expression-restrictive cells.

264 enes involved with global regulation of gene expression (SATB1) and the estrogen receptor alpha (ESR1

265 ction was not correlated with clinical PD-L1 expression scores in malignant melanoma.

266 ccRCC shows a gene expression signature consistent with adipogenesis, and t

267 as enhancers, but regions that repress gene expression-silencers-have not been systematically studie

268 with increased body temperature and BAT gene expression, specifically Cox8b.

269 We showed that H19X regulates DDIT4L gene expression, specifically interacting with a region upstr

270 The power of our method to correctly infer expression states is generally high and remarkably, appr

271 We demonstrate a novel viral gene expression strategy to target cells with specific miRNA

272 Aberrant biomarker expression stratified the cohorts into 3 distinct progno

273 Despite multiple gene expression studies becoming available, the limited overl

274 Developmental analysis of Ghrh and Kiss1 expression suggested that a subpopulation of ERalpha neu

275 is required for Pnr- and Srp-dependent gene expression, suggesting general GATA cofactor functions.

276 Using an inducible expression system, we observed that this ELANE mutation

277 flow dictated by geology, leading to surface expression that can be greater or less than the leakage

278 iant results in a mutant protein with mosaic expression that drives multi-organ immune dysregulation

279 Marmosets had a c-Fos expression that was notably more widely expressed (5x mo

280 ssociated TNF and dampened inflammatory gene expression through reverse signaling.

281 retains tubular formation, and reduces TRPM7 expression to normal levels.

282 This amplification-mediated gene expression tuning (AMGET) occurs on timescales that are

283 strategy to target cells with specific miRNA expression using miRNA-guided neuron tags (mAGNET).

284 We measured microRNA and mRNA expression using quantitative RT-PCR.

285 lence through aphB We further show that ompR expression was not altered by changes in osmolarity but

286 Gene expression analysis indicated VCP expression was particularly induced in aggressive thyroi

287 MMP-2 and MMP-9 expression was reduced in the skin of doxycycline-treate

288 Reduced surface expression was reflected by smaller IPSCs, which may und

289 nes and 4T1 mouse mammary tumor cells, PD-L1 expression was regulated by the nuclear receptor NR4A1/S

290 Accordingly, ChREBP target gene expression was rescued by re-expressing WT but not ChREB

291 The increase in CRF gene expression was similar across all groups; however, in fe

292 ation of thalamostriatal terminals when ChR2 expression was virally targeted to the intralaminar thal

293 miRNA-21-3p and miRNA-150-5p expression were significantly downregulated in patients

294 onal impacts of Kv2.1 depend on its level of expression, which varies with sex.

295 unveiling new functionalities of the genomic expressions, which might be dormant in a single-source a

296 tegrin blockade inhibited tECM-driven TGFBR2 expression, while inhibiting TGF-beta signaling decrease

297 X-2 activity that are independent of protein expression within live macrophage cells.

298 ligodendrocyte generation by restoring Sox10 expression without affecting canonical HIF1a activity.

299 h wide dynamic ranges that control transgene expression without the requirement of additional protein

300 DNA or RNA which can enhance or repress gene expression, yet the underlying molecular mechanism remai