ライフサイエンスコーパス: expression level

1 into account changes in both variability and expression level.

2 wed a positive correlation with its podocyte expression level.

3 l to discover cellular heterogeneity at gene expression level.

4 dimerization of Ca(2+) pumps with increasing expression level.

5 e various techniques used to manipulate Nlgn expression level.

6 o variable but independent of their baseline expression levels.

7 of heritability was mediated by assayed gene expression levels.

8 the opposite effect in GSCs with high ASCL1 expression levels.

9 from RNA-seq are reliable estimates of true expression levels.

10 ases are caused by mutations that alter gene expression levels.

11 not dependent on Set1 altering overall gene expression levels.

12 o reprogram chromatin state and to hone gene expression levels.

13 tracer uptake directly correlates to GLP-1R expression levels.

14 hins reduced the SGLT1 gene, but not protein expression levels.

15 the surface of living cells at physiological expression levels.

16 neurotransmission machinery at physiological expression levels.

17 a, and TNFalpha at both the gene and protein expression levels.

18 ectively) as accurately as the measured gene expression levels.

19 ses by associating phenotypes with predicted expression levels.

20 concentrations that highly exceed endogenous expression levels.

21 omalizumab did not significantly alter their expression levels.

22 tored and used for normalization to evaluate expression levels.

23 on is common and might in turn regulate gene expression levels.

24 iminate a range of tumor cell PD-L1 membrane expression levels.

25 elevated CD68, CD44, CD11c, PD-L1, and CD205 expression levels.

26 l and in some cases opposite effects on mRNA expression levels.

27 ediated by the cis genetic component of gene expression levels.

28 gesterone receptor, and Ki-67 labeling index expression levels.

29 e same variant influences both DNAm and gene expression levels.

30 y at high, low, or nonstoichiometric protein expression levels.

31 tein expression of MT-I/II reflect MT2A gene expression levels.

32 by these neocentromeres maintained wild-type expression levels.

33 th asthma severity, exacerbations, and GSDMB expression levels.

34 as maintained in spite of the reduced GLP-1R expression levels.

35 inhibited NB cell growth regardless of ABCG2 expression levels.

36 which 5 pairs with a strong change of target expression levels.

37 ts involve multiple genes displaying similar expression levels.

38 populations tend to gain broader and higher expression levels.

39 cell lines to DNMDP is correlated with PDE3A expression levels.

40 f four polyploid genomes at both genetic and expression levels.

41 structural (gDNA content) and activity (cDNA expression) levels.

42 cells in 3D cultures exhibited higher VEGFR2 expression levels, accelerated migration, invasion, and

43 tarctic-specific changes, we compared native expression levels across the full suite of chaperome gen

44 s have revealed substantial heterogeneity in expression levels among morphologically indistinguishabl

45 ar membrane quickly to promote the transgene expression level and kinetics in both adherent and suspe

46 x components in Neurospora led to high CAT-3 expression level and resistance to H(2) O(2) -induced RO

47 The degree of detachment depends on the expression level and the length of the activated gene.

48 ction-specific eQTLs that correlate with its expression level and to enteric infection susceptibility

49 cell lines and tumors exhibit enhanced PAK4 expression levels and activity, which are further activa

50 We demonstrate that sex influences gene expression levels and cellular composition of tissue sam

51 We studied gene expression levels and lung function in the Coronary Arte

52 forming an association analysis between gene expression levels and post-treatment tumor volume change

53 endent on the nature of the POLE allele, its expression level, and MMR status.

54 llected data on DNA sequences, messenger RNA expression levels, and patient survival times from 456 c

55 obiota and how this is regulated at the gene expression level are critical questions.

56 SphK2, and HIF-1alpha expression levels are elevated in metastatic estrogen re

57 egulated after glomerular injury because its expression levels are higher in the glomeruli of NTS inj

58 Importantly, we find that PSMB8 and PSMB9 expression levels are much stronger predictors of melano

59 ed an overall positive correlation with gene expression level as well as prominent associations with

60 logy and high vimentin, AKT1/2, and Galphai2 expression levels as predictive markers of response to c

61 Physiological mechanisms, like gene expression levels, as demonstrated in some Campylomormyr

62 evel of Snail but does not reduce E-cadherin expression level at the IC(50) (DPAGT1) concentration.

63 These methods first predict expression levels based on inferred expression quantitat

64 Six genes showed a significant difference in expression level between good and poor responders before

65 ces for exploring the balance of global gene expression levels between excitatory AMPA receptors (AMP

66 Comparison of gene expression levels between SUM149 cells with ERK2 or ERK1

67 IFN-alpha/-beta have very low basal expression levels but are strongly induced upon activati

68 duction genes or the same genes at different expression levels, but we do not know which molecular di

69 sized that shadow enhancers drive consistent expression levels by buffering upstream noise through a

70 s suggest genetic variants can decrease mRNA expression levels by increasing usage of intronic PAS.

71 d by B-cell lymphocytes and determined their expression levels by LC-MS/MS using both synchronous pre

72 These results suggest that PSMB8 and PSMB9 expression levels can serve as important biomarkers for

73 assessed the relationships between gene-set expression levels, cell abundance, and standardized effe

74 a potential HF biomarker candidate based on expression level changes in asymptomatic patients at fut

75 lower thermostability, and decreased protein expression levels compared with each of the single mutan

76 on in brain cell organization and/or pathway expression levels contribute to selective brain region v

77 Thus, double-SCR of MTCH2 regulates its own expression levels contributing toward the maintenance of

78 ally from active regulatory sequences, whose expression levels correlate with enhancer activity.

79 DDX21 expression levels correlated with non-mucinous histology

80 Taken together, our data suggest that WBP5 expression level could serve as an indicator for prognos

81 Thus, interferon-induced variability in ACE2 expression levels could be important for susceptibility

82 ther determined that sex differences in gene expression levels could be related to sex differences in

83 Unexpectedly, in many cases, these expression levels declined precipitously long before ble

84 cinomas (OPSCC) we noticed that, while ATP5B expression levels did not correlate with patient overall

85 eregulated histone acetylation, altered gene expression levels, distorted microRNA profiles, and a gl

86 gh-amplitude circadian rhythmicity with peak expression level during the early dark phase.

87 y and recapitulating oscillations in protein expression levels for a circadian clock model, we illust

88 stically verifiable increased variability of expression levels for most of the over 17 000 genes expr

89 35,458 cases, n = 344,901 controls) and gene expression levels from 21 tissue datasets (brain; blood;

90 These factors were associated with gene expression levels from RNA sequencing by using gene set

91 tative analysis of promoter occupancy versus expression level has suggested that unknown "trans facto

92 hrough the activation of STAT3, and low PTEN expression levels have a detrimental impact on patient d

93 ents whose tumors have low HPK1 and high AXL expression levels have shorter survival than those with

94 ar decline from year 20 to year 30, and gene expression levels (highest quartile divided into two lev

95 Here, we examined whether torsinB expression levels impact the onset or severity of abnorm

96 The FAM122A expression level in a tumor cell can serve as a useful b

97 Also, ADAR expression level in stage IV was higher than stage III.

98 ational buffering to maintain stable protein expression levels in 2iL-ESCs.

99 s of European ancestry and investigated gene expression levels in 7,773 samples.

100 (1) a pre-miR hairpin maturation assay, (2) expression levels in a Dicer null cell line, and (3) Ago

101 se DNA topoisomerase IIalpha protein 170 kDa expression levels in acquired resistance to etoposide.

102 Some lncRNAs show altered expression levels in autistic brains, but their roles in

103 The mRNA and protein expression levels in blood, brain, heart, intestine, kid

104 inconsistencies between MGMT methylation and expression levels in glioblastoma.

105 RNA-seq to measure cell cycle phase and gene expression levels in human induced pluripotent stem cell

106 a valid tool to systematically tune protein expression levels in mammalian cells and eventually help

107 ndent degradation resulting in lower protein expression levels in melanosomes than the dark skin-asso

108 t among the Wnt ligands with high endogenous expression levels in molars, Wnt4 was increased after ep

109 indicate that variants which influence gene expression levels in multiple tissues are more likely to

110 components in the blood as well as their RNA expression levels in muscle and bone.

111 ptor antagonist RU486 restored KLF15 and POX expression levels in mutant BAT, suggesting that loss of

112 o respond to exogenous auxin and AtDRO1 gene expression levels in root tips were unaffected by the ad

113 vels directly correlates and influences SMN2 expression levels in SMA patient cells.

114 lization screen that involves detecting GPCR expression levels in Spodoptera frugiperda (Sf9) culture

115 um euphorbiae) and has elevated constitutive expression levels in suppressor of prosystemin-mediated

116 is accompanied by normalizing of wg and hth expression levels in the eye imaginal disc.

117 he mechanism responsible for the drop in DMD expression levels in the presence of PTC.

118 laying an inverse correlation with the FATP4 expression levels in the RPE of the three mutant lines.

119 in atrial cardiomyocytes, along with protein-expression levels in tissue homogenates or cardiomyocyte

120 Higher gene expression levels in TLR5 and CCR1 are associated with l

121 e higher ADORA1, lower ATF3, and lower PD-L1 expression levels in tumor tissues from nonresponders am

122 hnical validation stage, miRNAs with altered expression levels in tumor vs nontumor tissues were quan

123 were tightly coexpressed, and their absolute expression levels increased with maximal firing rate.

124 nce in cancer clinical diagnosis because its expression level is closely related to malignant disease

125 Notably, expression level is influenced by weak regulatory intera

126 on can be faithfully transmitted to the gene expression level is unclear.

127 Gene expression levels measured with full transcript length s

128 clear whether this overlap is driven by gene expression levels 'mediating' genetic effects on disease

129 ow multiple SVs that changed gene dosage and expression levels modified fruit flavor, size, and produ

130 s under certain circumstances and that MFAP1 expression levels modulate the size, stability, and dyna

131 mple, the relative rather than absolute gene expression level needs to be considered, requiring diffe

132 ith a microarray analysis and focused on the expression level of 452 genes that are associated with t

133 Alterations in the expression level of alpha2delta subunits were implicated

134 The incidence and expression level of ATM correlated with pigmentary statu

135 The expression level of BRAF positively correlates with that

136 The expression level of CSP3 gene and CSP4 gene was higher i

137 Studies have shown that the expression level of different microRNAs (miRNAs) is alte

138 The expression level of FXRalpha2 in liver might be used to

139 ution algorithms cannot recover the accurate expression level of genes in many cases, inducing severe

140 Aim of the study is to evaluate the expression level of ITGAV in a very large collective of

141 As) in akr2a mutants were decreased, and the expression level of KCS1 was also reduced.

142 The expression level of MAD2 or CDC20 was positively correla

143 showed lower apoptosis rates at an increased expression level of MT2A after cisplatin treatment (from

144 Here, we found that the expression level of regulator of G protein signaling 12

145 estingly, in lnp1-1 lnp2-1 mutant cells, the expression level of RHD3 is higher than that in wild-typ

146 DPAGT1 inhibition by CPPB leads to a reduced expression level of Snail but does not reduce E-cadherin

147 thesis that in tauopathies the change in the expression level of specific miRNAs is an early event an

148 In contrast, the steady-state expression level of these genes show little dependence o

149 Our findings indicate that the expression level of tissue Ag is a key determinant of th

150 Expression levels of 19 immunoregulatory proteins in MTE

151 of total free amino acids per grain and the expression levels of 241 genes showed significant modifi

152 ys associated with HIV expression but higher expression levels of a subset of genes implicated in sup

153 Here we show that IGF1 alters the expression levels of a subset of lncRNAs.

154 e with LPS treatment significantly increased expression levels of alpha7nAChR in monocytes, alveolar

155 monocytes and alveolar macrophages, and low expression levels of alpha7nAChR were detected in inters

156 Native expression levels of Antarctic fish chaperomes showed ve

157 e introduce the APA-seq method to detect the expression levels of APA isoforms from 3'-end RNA-Seq da

158 We observed that hypoxia modulates the expression levels of approximately one-third of the EC t

159 Expression levels of both subunits of VLA-4, that is, in

160 the adult cerebellum has one of the highest expression levels of CB1R, but little is known about CB1

161 d activation over sCD40L evidenced by higher expression levels of CD83, CD86, HLA-DR and CD54, increa

162 RNA-seq analysis of murine BC revealed high expression levels of cholinergic and bitter taste signal

163 rk of transcriptional repressors to regulate expression levels of class A ARF proteins and modulate a

164 Furthermore, depletion of DYRK1A increased expression levels of cyclin L2.

165 Expression levels of dopaminergic markers were similar a

166 that TRPM4 activity can be regulated through expression levels of either TRPM4 or KCTD5, not only con

167 Pg infection reduced mRNA expression levels of endothelial NOS (eNOS), Nrf2, and P

168 The expression levels of eotaxin, IFN-gamma, IL-6, IL-8, IL-

169 tern blotting was carried out to investigate expression levels of epithelial and mesenchymal markers.

170 (UM, USC, and KCCRI) were used to assess the expression levels of ER-associated proteins using immuno

171 exist in chRCC and renal oncocytoma and that expression levels of ETC complex subunits can serve as a

172 Additionally, expression levels of eukaryotic translation initiation f

173 inal epithelium of Hnf4alphagamma(DKO) mice, expression levels of FAO genes, FAO activity, and metabo

174 Interestingly, the expression levels of farnesoid X receptor in liver and i

175 - and M-cones are negatively correlated with expression levels of FATP4 in the RPE of the KI, KI;Fatp

176 Expression levels of fatty acid oxidation, glucose metab

177 on the binding of FXR in mouse liver and the expression levels of FXR isoforms and gene targets in hu

178 ry stage of a long-term treatment, given the expression levels of genes collected in the previous tim

179 age of genes, suggesting that divergence in expression levels of genes critical for cell function wa

180 1 knockout reduces mitochondrial density and expression levels of genes involved in mitochondrial bio

181 generate large amounts of information about expression levels of genes.

182 We observed that the expression levels of GRP78 (p < 0.0001), ATF6 (p < 0.000

183 Higher expression levels of GSDMB correlated with asthma and gr

184 young adult counterparts when fold change in expression levels of GzmB, CD107a, IFN-gamma, and TNF wa

185 their observations are based on much higher expression levels of H-RasV12 than in our study and Lian

186 We investigated whether knocking down expression levels of HBV antigens in liver might increas

187 Owing to the high expression levels of HER2, combination therapies are cur

188 Expression levels of HLA-F and -G were correlated with t

189 The differential expression levels of HMGB proteins and/or mRNAs and thei

190 primary cells led to dramatically increased expression levels of HS3ST1, a key enzyme involved in im

191 e regulatory network (GRN)-that orchestrates expression levels of hundreds to thousands of genes in a

192 educed the level of ROS and H3K9me3, and the expression levels of IRE-1 and CHOP.

193 on of the integrin subunits ITGA3 and ITGB1; expression levels of ITGA3 and ITGB1 were reduced in cel

194 Over-expressing miR-195 reduces expression levels of its top predicted target synaptojan

195 lso revealed significant alterations in gene expression levels of key enzymatic regulators of biochem

196 ur results demonstrate that manipulating the expression levels of key sulfur assimilatory enzymes cou

197 he more competitive G. androsaceus with high expression levels of keystone functional genes.

198 ccessions of Solanum pennellii revealed that expression levels of known and novel candidate genes (pu

199 oxo knockdown was also confirmed by elevated expression levels of known ER stress markers.

200 Notably, the survival rate for the high expression levels of Lrp5, CSF1, and CD105 in tumor tiss

201 Expression levels of M and S opsin were quantified by we

202 H)(2)-D(3) was independent of maturation and expression levels of microRNA-155 and PU.1 (as upstream

203 , decreased histone acetylation, and altered expression levels of multiple genes.

204 ression of Tat or Exo-Tat doesn't change the expression levels of neuronal cytoskeletal marker beta3-

205 Targeting Notch1 in cancers that harbor high expression levels of Notch1 offers an addition to therap

206 FC expression data analysis showed decreased expression levels of NURR1 and ERR1 in patients with SCZ

207 ng the corticomedullary axis and quantitated expression levels of osmo-responsive genes.

208 attenuated aging-associated elevation in the expression levels of p21, mTOR/pS6, interleukin 6, and t

209 We show that high expression levels of p38alpha correlate with poor surviv

210 t contrast agent can be used to quantify the expression levels of PARP1 and to detect oral, oropharyn

211 pared with CD8+ T cells, with initially high expression levels of PD-1 and CTLA-4 that were associate

212 ses identified multiple SNPs associated with expression levels of post-GPI attachment to proteins 3,

213 M), in Nicotiana benthamiana We analyzed the expression levels of predicted intended-target and off-t

214 ignificant level of IL-1beta and had reduced expression levels of pro-IL-1beta in response to infecti

215 Expression levels of proinflammatory cytokines in the CN

216 s, less extensive demyelination, and reduced expression levels of proinflammatory cytokines within th

217 The expression levels of proliferating cell nuclear antigen

218 erial resources, affecting, for example, the expression levels of proteins dedicated to metabolism an

219 ed, including alternative splicing, and mRNA expression levels of proto-oncogenes and tumor suppresso

220 ia and decreased cell proliferation, altered expression levels of pyruvate dehydrogenase phosphatase

221 ing CD103(-) cells, with significantly lower expression levels of ribosomal proteins and transcriptio

222 The observed discrepancy between the expression levels of SATB1 mRNA and protein in developin

223 many cancer types have been linked with the expression levels of several of these architectural prot

224 rmed in studies of cell lines with different expression levels of signaling partners, and in experime

225 three steroid sulfates and co-localized with expression levels of SLC51A in several tissues.

226 Here, we explored how the expression levels of small GTPase proteins are regulated

227 ing of fast-spiking capacity by the absolute expression levels of specific ion channels provides a co

228 The mRNA expression levels of ST6GAL-I and SOX9 in human gastric

229 Here, we examined the expression levels of tau isoforms, their phosphorylation

230 dopaminergic neurons (mDANs) with different expression levels of tau.

231 scientific community is able to monitor the expression levels of tens of thousands of genes and prot

232 , the number of nucleated erythroblasts, and expression levels of TfR1, GATA1, and other erythroid ge

233 g1 (KO)/Tg(+) juveniles exhibited suppressed expression levels of Th2 markers, diminished MCM, suppre

234 retention events appear not to alter overall expression levels of the affected transcripts but rather

235 aled that a simple linear combination of the expression levels of the developmental genes is strongly

236 In Arabidopsis, natural variation in expression levels of the floral repressor FLOWERING LOCU

237 ato cultivars correlated positively with the expression levels of the genes involved in the phenylpro

238 lation between the amount of proteinuria and expression levels of the mechanosensor protein Filamin-B

239 soluble extracts of PRF membranes decreased expression levels of the osteoclast marker genes TRAP, C

240 Expression levels of the rate-limiting enzyme aromatase,

241 ecruitment and cell motility by reducing the expression levels of the receptor for HA-mediated motili

242 TM3-4 loop) of the GlyRalpha1 impair surface expression levels of the receptors.

243 beta-catenin signaling in GSCs that had low expression levels of the transcription factor ASCL1.

244 onship is conserved; however, changes in the expression levels of these genes can determine anthocyan

245 iral ganglion neurons, suggesting changes in expression levels of these genes in the hearing organ co

246 as to study the association between the gene expression levels of these six genes and lung function (

247 Finally, we analyzed expression levels of these TFs in dorsolateral prefronta

248 The mRNA expression levels of those genes encoding the identified

249 We then compared the expression levels of those markers in PBMCs taken from A

250 strategy was successfully used to assay the expression levels of TR in HeLa, HepG2 and HL-7702 cells

251 Expression levels of two proliferative markers, phospho-

252 n D in hPDLCs was assessed based on the gene expression levels of vitamin D receptor (VDR)-regulated

253 We evaluated pbp expression, levels of penicillin-binding protein (PBP) 5

254 eitis at days 7 and 22, and distribution and expression-levels of PAR-2, CGRP and c-Fos on day 22.

255 Immunoreactive-cells and expression-levels of spinal PAR-2, CGRP and c-Fos in the

256 This was not due to the reduced PDGFRbeta expression levels or decreased binding of the PDGF ligan

257 ual cells to fluctuate substantially in gene expression levels over time.

258 cted with T. gondii, as associated with high expression level (P <= 0.001) of Peak # 15 (2 x Neu5Gc)

259 Therefore, different combinations of CAM expression levels, plant sizes and shapes are available

260 pidly generating copy-number and, therefore, expression-level polymorphisms.

261 DNMT3B expression levels positively correlated with human metas

262 Differential tau isoforms, expression levels, promoters, and disruption of endogeno

263 l wall polysaccharides decomposition but low expression levels, reflecting a versatile ecology compar

264 Knockdown of MT2A expression levels resulted in significantly induced apop

265 ollowing acute LCMV infection, in which PD-1 expression levels return to near baseline, LSD1-deficien

266 Concordantly, tumor cells with high CXorf67 expression levels show increased sensitivity to poly(ADP

267 sgenic Brachypodium plants with elevated LNJ expression levels showed deregulation of JA signaling as

268 On the gene expression level, strategies are presented that make it

269 Interestingly, MYC expression levels strongly influenced beta-catenin activ

270 also increased with an increase in the pump expression level, suggesting improved catalytic efficien

271 methylation, chromatin modifications, TERRA expression levels, telomere sister chromatid exchange or

272 ting nuclease Cas9, with up to 5-fold higher expression level than classical cell-free systems.

273 are more likely to exhibit above high parent expression level than hybrids that do not express the si

274 At an expression level that equalizes the mean cell size with

275 lthough they are mainly used for quantifying expression levels, they contain much more biologically i

276 e models to edit genomes and to control gene expression levels through CRISPR interference (CRISPRi)

277 ative miRNA target predictions by transcript expression level, thus removing putative interactions wh

278 ors, subsequently changing their target gene expression levels to achieve therapeutic benefits - an a

279 Predictably regulating protein expression levels to improve recombinant protein product

280 but may immediately explore a wide range of expression levels to probe the optimal ones.

281 ith LRRC8C and/or LRRC8E, depending on their expression levels, to transport cGAMP and other 2'3'-cyc

282 We found that CPLX3 expression level was decreased twofold in cone-Bmal1(-/-

283 MCPIP1 expression level was higher in the liver tissue of HBV-i

284 Moreover, AURKB expression level was significant higher than AURKA in pa

285 tant to Pmel-1-directed ACT due to low gp100 expression levels was used to develop a homogenous time

286 Standardized gene expression levels were analyzed relative to enumerated c

287 Moreover, high platelet CD84 expression levels were associated with poor outcome in p

288 Furthermore, its expression levels were highly enhanced by bacterial chal

289 Cysteine-rich angiogenic inducer 61 (CYR61) expression levels were increased in the MITF.OE cells an

290 g was used to measure lung function and gene expression levels were measured using the Nanostring pla

291 Additionally, VDR and CYP27B1 expression levels were measured.

292 ed major histocompatibility complex class II expression levels were mediated through circulating bloo

293 In contrast, GLUT2 gene and protein expression levels were reduced after 2 hours exposure to

294 ADC imaging and surgical specimens, DCN RNA expression levels were significantly larger in high ADC(

295 PARP2 expression levels were significantly negatively associat

296 Expression levels were sought from both biomarkers toget

297 idermal growth factor (EGF) and amphiregulin expression levels were strongly reduced, resulting in re

298 maximal Ca(2+) load, together with the pump expression level, were analyzed.

299 activity was already attained at lower SUMF1 expression levels, while specific production rates stead

300 tion of CNOT1 variants revealed normal CNOT1 expression levels, with both mutant and wild-type allele