ライフサイエンスコーパス: ext

1 acellular domain of human Jagged-1 (Jagged-1(ext)).

2 ents indicated that the chimeric IL-15Ralpha(ext)/IL-2Ralpha(int) receptor still supports trans-prese

3 racellular domain of IL-2Ralpha (IL-15Ralpha(ext)/IL-2Ralpha(int)) and examined its function in 32D c

4 etrics exceeding 0.8 (Q(2)cv = 0.864 and Q(2)ext = 0.873).

5 ds the best result (R(2)(train) = 0.93, R(2)(ext) = 0.70).

6 es with increasing external Ca(2+), [Ca(2+)](ext), for small levels of [Ca(2+)](ext).

7 [Ca(2+)](ext), for small levels of [Ca(2+)](ext).

8 ) whose activity is reduced by high [Ca(2+)](ext).

9 tical performance; that is, r(2) = 0.89, r(2-ext) = 0.72 and 0.73 for training and external validatio

10 ch fraction after thioglycolysis, a dimer A2-ext and a molecule that corresponds to a linkage between

11 take of (131)I- and (111)In-labeled antiPSMA(ext) mAbs (J415, J533, and J591) and their potential uti

12 ATP(ext) also induced a slower process of DNA fragmentation

13 ATP(ext) had an additive effect with TCR cross-linking in th

14 receptors in thymocytes is reflected by ATP(ext)-induced intracellular calcium increases and by thym

15 Described here, the properties of ATP(ext) and adenosine are consistent with their involvement

16 t-specific sensitivity to the effects of ATP(ext) and adenosine.

17 death, but, unexpectedly, the effects of ATP(ext) at high concentration were antagonistic to steroid-

18 Only ATP(ext), but not the ATP catabolites, adenosine, dexamethas

19 of extracellular adenosine triphosphate (ATP(ext)) and adenosine on TCR- and steroid hormone-triggere

20 ng independent measurements of b(scat) and b(ext).

21 light scattering (b(scat)) and extinction (b(ext)) coefficient by dispersed aerosols.

22 While measurement standard deviations for b(ext) and b(scat) were generally <1 Mm(-1) when the measu

23 2) affinity, external carbonic anhydrase (CA(ext) ), isotopic signatures (d(13) C) and growth among s

24 2) affinity, external carbonic anhydrase (CA(ext) ), isotopic signatures (delta(13) C) and growth amo

25 ecies, with higher CO(2) affinity, higher CA(ext) and higher d(13) C.

26 ecies, with higher CO(2) affinity, higher CA(ext) and higher delta(13) C.

27 hat reduce Ca(2+) influx, indicating that Ca(ext)(2+) is a source for the transient.

28 be induced by elevated external Ca2+ ([Ca2+](ext)), which promoted very rapid spiking of [Ca2+](cyt)

29 Our data indicate that elevated [Ca2+](ext) acts to disrupt Ca2+ homeostasis which induces defl

30 Elevated [Ca2+](ext) also results in further [Ca2+](cyt) elevations afte

31 Although basal DA(ext) did not differ, cocaine-evoked DA(ext) was greater

32 Extracellular DA concentration (DA(ext)) and extraction fraction (E(d)), an indirect measur

33 nd cocaine-evoked extracellular dopamine (DA(ext)) levels as well as basal DA uptake rate and cocaine

34 It increased cocaine-evoked DA(ext) and decreased the cocaine-induced inhibition of upt

35 The finding that cocaine-evoked DA(ext) is higher in naive and cocaine-exposed HRs suggests

36 al DA(ext) did not differ, cocaine-evoked DA(ext) was greater in HRs.

37 Basal uptake, but not DA(ext), was lower in HRs, indicating lower basal DA releas

38 r domain of the Notch ligand, Delta-1 (Delta(ext-myc)), induces apoptosis in peripheral blood monocyt

39 However, Delta(ext-myc) permitted differentiation into immature dendrit

40 Results showed that immobilized Delta(ext-myc) inhibited differentiation of monocytes into mat

41 endritic cells (51% in the presence of Delta(ext-myc) versus 10% in control cultures), whereas a decr

42 With GM-CSF and TNF-alpha, exposure to Delta(ext-myc) increased the proportion of precursors that dif

43 h increasing densities of immobilized Delta1(ext-IgG) consisting of the extracellular domain of Delta

44 of purified immobilized Notch ligand (Delta1(ext-IgG)) induced increased expression of Notch targets

45 h exogenously presented Notch ligand, Delta1(ext-IgG), consisting of the extracellular domain of Delt

46 Higher densities of Delta1(ext-IgG) also enhanced the generation of Sca-1(+)c-kit+

47 Lower densities of Delta1(ext-IgG) enhanced the generation of CD34+ cells as well

48 nd that relatively lower densities of Delta1(ext-IgG) enhanced the generation of Sca-1(+)c-kit+ cells

49 er, culture with increased amounts of Delta1(ext-IgG) induced apoptosis of CD34+ precursors resulting

50 findings demonstrate the potential of Delta1(ext-IgG)-cultured cells for accelerating early immune re

51 w that culture of LSK precursors with Delta1(ext-IgG) increases the number of progenitors that are ab

52 tion of murine marrow precursors with Delta1(ext-IgG), a Notch ligand consisting of the Delta1 extrac

53 formance (30 000 cd/m(2) luminance; 2.0% eta(ext); 4.0 V turn-on voltage).

54 observed (64 000 cd/m(2) luminance; 2.3% eta(ext); turn-on voltages as low as 3.5 V).

55 .6% forward external quantum efficiency (eta(ext)), and 5 V turn-on voltages are achieved, affording

56 reading frame [ORF]), an AT-rich extension (ext-a1) of the core ORF and an AT-rich region following

57 ulated efficiencies of mispair extension ( f ext) were, in general, not significantly decreased from

58 sion efficiencies just beyond the lesions (f(ext)) are generally smaller than f(ins) and also depend

59 equency of translesion synthesis (F(ins) x F(ext)) of dC.dG-N(2)-BPDE pairs was 2-6 orders of magnitu

60 This identifies Glu(ext) as a major component of the gating charge underlyin

61 an inward movement of the side chain of Glu(ext), followed by the binding of extracellular Cl(-) ion

62 extets in the Mossbauer spectrum at 4.2 K (H(ext) = 0) which converge to a single six-line pattern in

63 ) (K(int) = [E.P.UCGA]/[E.S.UCG] = 4.6 and K(ext) = [P][UCGA]/[S][UCG] = 1.9).

64 unperturbed from the solution equilibrium, K(ext) (K(int) = [E.P.UCGA]/[E.S.UCG] = 4.6 and K(ext) = [

65 ux at low external K(+) concentration ([K(+)]ext = 22.5 microm) was predominantly mediated by AtAKT1

66 m active to passive K(+) uptake at low [K(+)]ext and yielding fluxes as high as 36 micromol g (root f

67 kt1, athak5, and athak5 atakt1) at low [K(+)]ext, revealing the concerted involvement of several tran

68 (root fresh weight)(-1) h(-1) at 5 mm [K(+)]ext, among the highest transporter-mediated K(+) fluxes

69 "IB" (interburst) state, and a set of [K(+)](ext) and voltage-dependent "C" (closed) states.

70 to the Myb domain called Myb-extension (Myb-ext) that is absent in TRFL family 2 and hTRF1/hTRF2.

71 Removal of the Myb-ext domain from TRFL1, a family 1 member, abolished DNA

72 However, when the Myb-ext domain was introduced into the corresponding region

73 Thus, Myb-ext is required for binding plant telomeric DNA and defi

74 f extracellular Na(+) concentration ([Na(+)](ext)).

75 Na(X) channel and regulates the high [Na(+)](ext)-evoked Na(+) current via influencing the Na(+) infl

76 isoform is specifically involved in [Na(+)](ext) detection.

77 )/K(+)-ATPase play a central role in [Na(+)](ext) detection.

78 intracellular regulatory pathway of [Na(+)](ext) detection in MnPO neurons.

79 vations, we suspect a translation product of ext-a1 affects different regulatory mechanisms that cont

80 this limitation by using an extended pegRNA (ext-pegRNA) with modified 3' extension, and an additiona

81 The localization of radiolabeled anti-PSMA(ext) antibodies in PSMA-positive LNCaP tumors was highly

82 of necrosis whereas J415 and J591 (anti-PSMA(ext)) demonstrated a distinct preferential accumulation

83 ty to the extracellular domain of PSMA (PSMA(ext)).

84 ause J591 and J415 mAbs are specific to PSMA(ext), thus targeting viable tumor, these immunoconjugate

85 capacity for the test set with R(ext)(2) = Q(ext)(2) values in the range of 0.639-0.823 and 0.767-0.8

86 predictive capacity for the test set with R(ext)(2) = Q(ext)(2) values in the range of 0.639-0.823 a

87 (S(int)), central (S(cen)), and external (S(ext)).

88 (ex)) residue acts as a gate competing for S(ext).

89 (ex) is essential for Cl(-) transport from S(ext) to S(cen).

90 ociated with transport of a Cl(-) ion from S(ext) to S(int), depending on the Cl(-) occupancy of othe

91 Cl(-) favorably occupies an exterior site, S(ext), to form a queue of anions in the pore.

92 y two components: dCas9 and extended sgRNAs (ext-sgRNAs).

93 attering (sigma(scat)) and extinction (sigma(ext)) cross sections for size-selected ammonium sulfate

94 ooxygenation product is the less stable SREP-ext stereoisomer with the endoperoxide unit directed out

95 ent reactivity of mechanically strained SREP-ext depend on the size of the end groups of the encapsul

96 he interlocked components, the strained SREP-ext stereoisomer undergoes clean thermal cycloreversion.

97 sure ( P (0)) and at ambient temperature ( T ext).

98 verexpression of the ext-a1 sequence and the ext-a1 3' region, which includes a partial sequence of d

99 we study the effect of overexpression of the ext-a1 sequence and the ext-a1 3' region, which includes

100 ciently perform editing on both sides of the ext-pegRNA nick, a task that is unattainable by canonica

101 base pairs within the upstream region of the ext-pegRNA nick.

102 -sgRNA) targeting the upstream region of the ext-pegRNA.

103 k, we develop a tumor phylogeny method, TUSV-ext, which incorporates SNVs, CNAs and SVs into a single