ライフサイエンスコーパス: extra-

1 pa reduced daily off-time by, on average, an extra -1.17 h (95% CI -1.69 to -0.66; p<0.0001) compared

2 m a large cohort of 148 ALE patients (33 ALE(extra), 12 ALE(intra), 28 ALE-GAD65, 37 ALE(abneg)) in c

3 aved, with incremental costs ranging from an extra $27,313 to saving $20,756.

4 some-IRES complex in a rotated state with an extra ~3 degrees of rotation.

5 olving charged or polar side chains, (ii) an extra, 38-amino-acid repeat inserted between FnBR-9 and

6 ismatch repair in neoplasia is manifested by extra, aberrant bands within multiple microsatellite mar

7 must be non-toxic, non-immunogenic, overcome extra- and intra-cellular barriers, protect the nucleic

8 roteome resides at the interface between the extra- and intra-cellular environment and through its va

9 t translocate a variety of substrates across extra- and intra-cellular membranes.

10 Anti-GA antibodies engaged extra- and intra-cellular poly-GA and reduced aggregate

11 ascularized tumor growth, and the associated extra- and intra-cellular protein outflux from these pop

12 t resistances including membrane resistance, extra- and intra-cellular resistances for NO biotranspor

13 that these specialized cells integrate both extra- and intra-cellular signals in the control of stom

14 nucleostemin cycle is designed to translate extra- and intra-cellular signals into the amount of nuc

15 Here we simultaneously monitor extra- and intra-mitochondrial Ca(2+) and mitochondrial

16 Total water and the extra- and intra-particulate water components were deter

17 ich permit the clock mechanism to respond to extra- and intra-SCN chemical messengers.

18 We investigated the role of extra- and intracellular acidification on heterologously

19 within any given cortical layer, oscillatory extra- and intracellular activity was highly synchronous

20 We also determined the amount of extra- and intracellular Ag by chemically etching AgNPs

21 rcuits allow engineered T cells to integrate extra- and intracellular antigen recognition, are robust

22 been widely used for the measurement of both extra- and intracellular calcium.

23 wn of encystation, sporulation requires both extra- and intracellular cAMP.

24 EUF, membrane permeability to CO(2), native extra- and intracellular carbonic anhydrase-like activit

25 organelles that function to catabolize both extra- and intracellular cargo, act as a platform for nu

26 Extra- and intracellular catalytic activity of CA IV cou

27 ing and computational modeling, we find that extra- and intracellular Cn support distinct modes of NF

28 er contribute to the processing of AGEs from extra- and intracellular compartments and in the cellula

29 tochondrial function, O(2) gradients between extra- and intracellular compartments may vary and play

30 An oxygen gradient between the extra- and intracellular compartments was observed in WT

31 tial exit ports for cleavage products to the extra- and intracellular compartments.

32 e components of other viruses as well as the extra- and intracellular constituents of host cell lipid

33 nteraction with AMPA receptors involved both extra- and intracellular determinants of TARPs.

34 could be mapped to contributions of both the extra- and intracellular domains of these receptors.

35 yclonal antibodies directed against distinct extra- and intracellular domains specifically immunoprec

36 ynaptic density protein 95 (PSD-95), bind to extra- and intracellular domains, respectively, but are

37 all analogs was assessed against a panel of extra- and intracellular endoproteases, whereas their in

38 The innate immune system surveys the extra- and intracellular environment for the presence of

39 y provide a sequence specific signal in both extra- and intracellular environments.

40 tion of homocystinuria model mice alters the extra- and intracellular equilibrium of sulfur amino aci

41 eved by ensuring proper distribution between extra- and intracellular fluid compartments and by match

42 normal potassium (K+) concentrations in the extra- and intracellular fluid is critical for cell func

43 esentative P-type pump, after uncoupling its extra- and intracellular gates with the marine toxin pal

44 Alternatively, both extra- and intracellular GFP fluorescence was exquisitel

45 To monitor extra- and intracellular glutamate concentrations in pla

46 esses ongoing infection by inactivating both extra- and intracellular infectious particles, and it is

47 A number of promising extra- and intracellular inhibitors of fat cell formatio

48 ibition of K(+) currents, a reduction in the extra- and intracellular levels of Abeta, and a decrease

49 the delivery hurdles related to the varying extra- and intracellular localizations of innate immune

50 2-14 A separates the N- and C-termini of the extra- and intracellular loops.

51 t response to TSLP, and further to study the extra- and intracellular mechanisms involved in this pro

52 hese processes, along with a growing list of extra- and intracellular mediators that includes endocan

53 We also established a method to obtain extra- and intracellular MPO from murine organs.

54 tablished and validated a protocol to obtain extra- and intracellular MPO from murine organs.

55 adhesion by analyzing targeted mutations of extra- and intracellular Neuroglian domains in combinati

56 nd the metastable nature of interaction with extra- and intracellular partners that drive their effec

57 bution of the 9 major inorganic ions between extra- and intracellular phases was essentially equal to

58 ling in human physiology and disease through extra- and intracellular processes.

59 -DOTA reaction with tetrazines optimized for extra- and intracellular reactivity, the label was remov

60 te matter has been shown to activate various extra- and intracellular receptors of airway epithelial

61 We further performed extra- and intracellular recordings of thalamic cells in

62 Extra- and intracellular recordings using sharp electrod

63 e (ELL) in the hindbrain by field potential, extra- and intracellular recordings, and intracellular l

64 and provides a mechanism for the independent extra- and intracellular regulation of postnatal neural

65 ntiation rely on the controlled interplay of extra- and intracellular regulatory factors.

66 mination of permeability differences between extra- and intracellular S. aureus, thus providing a roa

67 that nanodiamond-induced alterations in both extra- and intracellular secondary protein structures le

68 with similar alternative splicing and large extra- and intracellular sequences.

69 but it is sensitive to mutations on both the extra- and intracellular sides of the channel.

70 Bacteria must integrate extra- and intracellular signaling information to mount

71 Bacteria use diverse small molecules for extra- and intracellular signaling.

72 which also require priming, ensures diverse extra- and intracellular signals interface with Cdc25A t

73 -RpaA clock output system integrate relevant extra- and intracellular signals to the circadian clock.

74 mTORC1 is regulated by a wide range of extra- and intracellular signals, including growth facto

75 nism for cross-regulation of ion channels by extra- and intracellular signals.

76 mass spectrometry, to quantitatively analyze extra- and intracellular silver (Ag) in individual Ag NP

77 phagocytic uptake required Ca(2+) from both extra- and intracellular sources apart from PI3K, microt

78 rious properties of inhibitors including the extra- and intracellular stability, the dose- and time-d

79 le compounds with nanomolar activity against extra- and intracellular stages of T. cruzi.

80 ipid metabolism are regulated in response to extra- and intracellular stimuli and in turn serve as re

81 are key cellular organelles that metabolize extra- and intracellular substrates.

82 bortus O antigen appears to be essential for extra- and intracellular survival in mice.

83 the bacterial homologue LeuT, which possess extra- and intracellular thin gates, is an excellent mod

84 Extra- and intracellular titrations showed that endogeno

85 xpression by itself, it synergizes with both extra- and intracellular Toll-like receptor ligands and

86 show that cells tolerate crystallization of extra- and intracellular water.

87 on pathway where they become inaccessible to extra- and intracellular water.

88 the production of LukAB, which serves as an extra- and intracellular weapon to protect the bacterium

89 ly after infection, Cn is detectable as both extra- and intracellular yeast particles, with Cn being

90 nd gibepyrone A production was enhanced both extra- and intracellularly in Deltagpy2 mutants.

91 y (81%) of non-serotonergic neurons recorded extra- and intracellularly in the DRN; the ENK effect re

92 iments demonstrated a phase reversal of both extra- and intracellularly recorded activity near the lo

93 aches to targeting the NGF-TrkA pathway both extra- and intracellularly.

94 ory mechanisms synthesize to ensure that the extra- and intracelluller fluid K+ concentrations remain

95 Extra- and intracranial ablated layers showed distinct p

96 r color duplex ultrasound examination of the extra- and intracranial cerebral arteries were enrolled

97 Paired extra- and intracranial NGS was available for 14 patient

98 ived cells contribute to the genesis of both extra- and intraembryonic blood vessels in the early qua

99 e yolk sac and then rapidly migrate to other extra- and intraembryonic tissues.

100 a progressive fibroinflammatory disorder of extra- and intrahepatic bile ducts, is the most common i

101 1.17-1.57) and 1.47 (95% CI, 1.19-1.80) for extra- and intrahepatic duct cancer, respectively.

102 rt a relationship between gene expression in extra- and intrathoracic airway epithelial cells and ext

103 ing the difference in shedding rates between extra- and non-extracellular proteins from viable and ne

104 on of D2 in pre- and postsynaptic as well as extra- and perisynaptic structures of the primate prefro

105 od of solving the whole 3D structures of the extra- and the intracellular domains of the TP receptor.

106 edded regions and distinguishing between the extra- and trans-membrane domains of membrane proteins.

107 by sacrificing part of sunlight to provide "extra" asymmetrical field continuously as to drive photo

108 lectron diffraction (CBED) patterns exhibit "extra" Bragg's reflections (compared to CBED of cubic-pe

109 eiving multiple injections had one or a few 'extra' BrdU-positive nuclei near the proliferation zones

110 int toward an accumulation of sodium ions in extra- but not in intracellular space in combination wit

111 hyaluronan, an important constituent of the extra- cellular matrix of connective tissues, through an

112 kJ/mol difference), which corresponds to one extra (cumulative) hydrogen bond for cellobiose over lac

113 As in the S. aureus enzyme, these "extra" cysteines apparently shuttle a disulfide bond to

114 xhibited features of neuro-inflammation, ALE(extra) displayed features of neuro-inflammation as well

115 The drop in [K(+)](extra) during light activation leads to a small (2-3 mV)

116 ty for their low costs, high sensitivity and extra (e.g. spatial) information; however, they typicall

117 of the c-PFA radical anions reveal that the "extra" electron is largely localized on the unique F ato

118 aced with Phe (F), blocking transfer of the "extra" electron that occurs in wt R2 during formation of

119 with antibodies targeting extracellular (ALE(extra)) epitopes, intracellular (ALE(intra)) epitopes, a

120 n; it deviates from most tmRNAs in having an extra (fifth) pseudoknot and a branched structure at the

121 ects of fMRI invisible ("missing") sources, "extra" fMRI sources, and cortical orientation errors.

122 Extra "forbidden" meridional reflections, at orders of 4

123 city of pockets within the ensembles adds an extra, fourth dimension to the Pocketome entry data.

124 Remarkably, in every case, the 'extra' genes are expressed in a testis-specific manner.

125 noncanonical IgV-like topology including an extra "H" beta-strand and "clamping" disulfide, absent i

126 These "extra" hemins form a stacked pair with a structure simil

127 Second, we found two 'extra' Hox genes in the centipede compared with those in

128 3, were reviewed to determine the number of "extra" images.

129 ded extracellular K(+) concentration ([K(+)](extra)) in neocortical brain slices prepared from young

130 bulk filling technique (bulk filling with an extra, indirect curing step) can increase the tensile bo

131 These "extra" interactions foster potent rhomboid inhibition in

132 sed to generate the low-energy conformers in extra, intracellular, and membrane-inserted environments

133 l adaptation of Ditrysian Orcos to acidified extra-/intracellular environment.

134 tmental model (2TC) as well as a 2TC with an extra, irreversible, compartment for endothelial binding

135 neurons are being hyperpolarized and [K(+)](extra) is low.

136 he primary site of interaction between this 'extra' LHCII and the PSI-LHCI-LHCII supercomplex in stat

137 Roche Diagnostics), INNO-LiPA HPV Genotyping Extra (LiPA) (Innogenetics), and the reverse hybridizati

138 It is proposed that the "extra" malate represents a stage in the transfer of subs

139 OCAM sequences into NCAM Ig5, including an "extra" N-glycosylation site, decreases or completely blo

140 One possibility is that these "extra" neurons are used to overcome cortical noise and f

141 xposed animals, because the number of these "extra" neurons was equal to only half that of missing ne

142 B chromosomes are extra, non-essential chromosomes present in addition to

143 ream CCA with an increased propensity to add extra "non-coded" nucleotides to the 5' end of the cDNA

144 embryos transferred, and cryopreservation of extra, nontransferred embryos (an indicator of higher em

145 Mutation of either an extra- or an intracellular pH sensor blunted the cross-i

146 t SPC can modulate transmitter release by an extra- or intracellular action at the frog motor nerve e

147 DSI in PFC neurons was abolished by extra- or intracellular application of tetrahydrolipstat

148 ectifying cationic current in the absence of extra- or intracellular Ca(2+) that was reduced upon rep

149 gram Salmonella gene expression to cope with extra- or intracellular challenging conditions.

150 PD-L1, but not mutants with deletion of its extra- or intracellular domain.

151 eria grown in conditions designed to emulate extra- or intracellular environments in vivo.

152 ccessibility method was utilized to localize extra- or intracellular loops connecting predicted PCFT

153 Extra- or intracellular recordings were made from sevent

154 faster (within tens of nanoseconds) into the extra- or intracellular regions.

155 These result in extra- or intracellular release of interferogenic nuclei

156 Autophagy is upregulated in response to extra- or intracellular stress and signals such as starv

157 er the delivery molecule should be localized extra- or intracellularly to produce desired biological

158 y markers and retaining functions of primary extra- or intrahepatic duct cholangiocytes within 2 week

159 med to determine in a quantitative manner if extra- or intramitochondrial Ca(2+) modulates oxidative

160 a GABAA receptors, thought to mediate tonic (extra- or perisynaptic) inhibition, are unknown.

161 We theorize that the presence of extra, otherwise unexplainable specificities could be ac

162 fe of cherry tomatoes up to 35 days (15 days extra) over the control without compromising quality and

163 Here we show that extra, plasmid-borne copies of an rRNA operon recruit RN

164 ogenic, acquiring that mutation would add an extra, potentially time-consuming step in carcinogenesis

165 we uncovered that though fated to die, the 'extra' precursor is specified as an L5.

166 fferentiate into neurons, called L1-L5; the 'extra' precursor, which is invariantly positioned above

167 e differentiation signalling to prevent the 'extra' precursors from differentiating, resulting in the

168 er than bacterial ribosomes, because of the 'extra' proteins they contain.

169 ith O2 and satisfies the requirement for an "extra" reducing equivalent in Y(*) generation.

170 X intermediate (1) requires transfer of an "extra" reducing equivalent to the buried diiron cluster

171 Our data indicate that the "extra" residue in transmembrane domain 10 of the GABA tr

172 the Posterior sex combs (Psc) and Sex combs extra (Sce) proteins.

173 Super-resolution microscopy reveals extra, short-A-bands lying close to the outer muscle cel

174 xpressing dominant negative PKA also induced extra, sometimes multiple digits, from anterior limb bud

175 lbert's syndrome, has been attributed to two extra (TA) bases in the TATAA-box of the promoter region

176 tivation induced a pronounced drop in [K(+)](extra) that persisted for the duration of illumination.

177 pt to life as a dedicated bamboo feeder, its extra "thumb" is arguably the most celebrated yet enigma

178 strained VO2(B) nanodomains combined with an extra (Ti,V)O2 layer on the TiO2 terminated STO (001) su

179 sted the hypothesis that the transition from extra- to intracellular environments during Salmonella i

180 ctors in the S. flexneri transition from the extra- to the intracellular milieu.

181 th PSII in state 1 in higher plants (called "extra" trimers).

182 f 1 with alkynes can be associated with the "extra" two Ru-H hydrides on the framework of 1 which are

183 of dimerization partners and by inserting an extra, unpaired Cys residue to create an opportunity for

184 ion of a punctuated mRNA is possible with an extra, unpaired nucleotide between codons.

185 Clonal analysis of the "extra" vegetative nodes reveals that these nodes are the

186 The large set of "extra" virulence functions encoded by both PAPIs may con

187 great part of the column only acts as void (extra) volume.

188 know we are not physically fit unless we do extra, voluntary exercise.

189 the mammalian cells and to distinguish their extra- vs intra-cellular localizations by real-time spec

190 Expression of PTPmu-extra (which lacks most of the cytoplasmic domain) induc