ライフサイエンスコーパス: extracellular signal-regulated kinase

コーパス検索結果 (１語後でソート)

通し番号をクリックするとPubMedの該当ページを表示します

1 kinase interacting kinase-1, downstream from extracellular signal-regulated kinase.

2 osphorylation of phospholipase C gamma-1 and extracellular signal-regulated kinase.

3 r and activator of transcription 5, Akt, and extracellular signal-regulated kinase.

4 s and sAC is required for the acute phase of extracellular signal regulated kinase 1/2 activation tri

5 cardiovascular disease, is known to activate extracellular signal regulated kinases 1 and 2 (ERK1/2).

6 Extracellular signal-regulated kinase 1 (ERK1), a member

7 kinase 1 (MAP2K1), the gene that encodes MAP-extracellular signal-regulated kinase 1 (MEK1).

8 phorylation switch of IRS1/2 orchestrated by extracellular signal-regulated kinase 1 and 2 (ERK1/2) a

9 sults in the nuclear translocation of active extracellular signal-regulated kinase 1 and 2 (ERK1/2),

10 f BRAF/NRAS mutations and hyperactivation of extracellular signal-regulated kinase 1 and 2 (ERK1/2),

11 e to PDGF-BB, and reduced phosphorylation of extracellular signal-regulated kinase 1 and 2, Elk-1, p3

12 cell activation, as well as inflammasome and extracellular signal-regulated kinase 1 and 2-mediated n

13 in treatment and INSM1 inhibition suppressed extracellular signal-regulated kinase 1/2 (ERK1/2) activ

14 d transient IkappaBalpha phosphorylation and extracellular signal-regulated kinase 1/2 (ERK1/2) activ

15 ct resulted from cell-specific regulation of extracellular signal-regulated kinase 1/2 (ERK1/2) activ

16 that NPNT stimulates the phosphorylation of extracellular signal-regulated kinase 1/2 (ERK1/2) and p

17 Recent work suggested that the activity of extracellular signal-regulated kinase 1/2 (ERK1/2) is in

18 n target of rapamycin complex 1 (mTORC1) and extracellular signal-regulated kinase 1/2 (ERK1/2) pathw

19 pathways, including the NF-kappaB, AKT, and extracellular signal-regulated kinase 1/2 (ERK1/2) pathw

20 N-gamma, and the JAK1, STAT1, NF-kappaB, and extracellular signal-regulated kinase 1/2 (ERK1/2) pathw

21 inositol monophosphate (IP(1)) accumulation, extracellular signal-regulated kinase 1/2 (ERK1/2) phosp

22 s found to be dependent on activation of the extracellular signal-regulated kinase 1/2 (ERK1/2) signa

23 U50,488H-induced activation of extracellular signal-regulated kinase 1/2 (ERK1/2) was G

24 e (PI3-K), protein kinase C-zeta (PKC-zeta), extracellular signal-regulated kinase 1/2 (ERK1/2), NF-k

25 rotein kinase (MAPK) signaling, encompassing extracellular signal-regulated kinase 1/2 (ERK1/2), p38

26 the eIF4E upstream kinase) or inhibitors of extracellular signal-regulated kinase 1/2 (ERK1/2), the

27 iptolide binds to and activates p38alpha and extracellular signal-regulated kinase 1/2 (ERK1/2), whic

28 asmin generation, but instead is mediated by extracellular signal-regulated kinase 1/2 (ERK1/2)-regul

29 only combined treatment of mitogen-activated extracellular signal-regulated kinase 1/2 (MEK1/2) and S

30 R321 inhibits only the early phase of extracellular signal-regulated kinase 1/2 activation and

31 f both intracellular Ca(2+) mobilization and extracellular signal-regulated kinase 1/2 activation, wh

32 C cells and resulted in potent inhibition of extracellular signal-regulated kinase 1/2 activation.

33 A cell lines in a dose-dependent manner, and extracellular signal-regulated kinase 1/2 and AKT.

34 -mediated signalling pathway, including p38, extracellular signal-regulated kinase 1/2 and c-Jun N-te

35 ulated PgLPS-mediated phosphorylation of the extracellular signal-regulated kinase 1/2 and c-Jun N-te

36 to a series of downstream events, including extracellular signal-regulated kinase 1/2 and c-Jun N-te

37 on of GluN2B and inactivation of the kinases extracellular signal-regulated kinase 1/2 and Fyn.

38 cKL + FGF23 increased the phosphorylation of extracellular signal-regulated kinase 1/2 and induced Fg

39 hosphates) in some signaling events, such as extracellular signal-regulated kinase 1/2 and label free

40 cted with the LRP1/NMDA-R system to activate extracellular signal-regulated kinase 1/2 and promote ce

41 and was coupled with decreased expression of extracellular signal-regulated kinase 1/2 kinase signali

42 assays, and ChIP revealed that DDR2 acts via extracellular signal-regulated kinase 1/2 mitogen-activa

43 pling, betaarr recruitment, endocytosis, and extracellular signal-regulated kinase 1/2 mitogen-activa

44 that Ach upregulated TGFbetaRII through Src-extracellular signal-regulated kinase 1/2 pathway to pot

45 i) coupling as measured by cAMP response and extracellular signal-regulated kinase 1/2 phosphorylatio

46 urally distinct MEKi trametinib and elevated extracellular signal-regulated kinase 1/2 phosphorylatio

47 s down-regulated, followed by an increase in extracellular signal-regulated kinase 1/2 phosphorylatio

48 ells, Ptges expression was regulated through extracellular signal-regulated kinase 1/2 phosphorylatio

49 ray of mechanistic studies revealed impaired extracellular signal-regulated kinase 1/2 signaling in H

50 n-1-SYK-epidermal growth factor receptor-AKT/extracellular signal-regulated kinase 1/2 signaling path

51 inhibiting cAMP accumulation and activating extracellular signal-regulated kinase 1/2 signaling whil

52 n high glucose condition interferes with Src-extracellular signal-regulated kinase 1/2 signaling, res

53 ading to activation of MAPK kinase (MEK) and extracellular signal-regulated kinase 1/2 signaling; how

54 was transactivated by Src family kinases and extracellular signal-regulated kinase 1/2 was activated

55 nase p38 was enhanced and phosphorylation of extracellular signal-regulated kinase 1/2 was decreased

56 ayed rapid increases in activated STAT1/3/5, extracellular signal-regulated kinase 1/2, AKT, CREB, an

57 es and were associated with an activation of extracellular signal-regulated kinase 1/2, and ribosomal

58 r and activator of transcription 5, AKT, and extracellular signal-regulated kinase 1/2, determining i

59 ory effects, increased inhibition of phospho-extracellular signal-regulated kinase 1/2, increased mit

60 nt phosphorylation of the downstream kinases extracellular signal-regulated kinase 1/2, mitogen-activ

61 ey signaling intermediates protein kinase B, extracellular signal-regulated kinase 1/2, NF-kappaB, an

62 ng MMP-9 secretion through the activation of extracellular signal-regulated kinase 1/2, p38, phosphoi

63 down resulted in decreased levels of phospho-extracellular signal-regulated kinase 1/2, phospho-c-Jun

64 Strategies to inhibit extracellular signal-regulated kinase 1/2, ribosomal S6

65 STAT3, which is significantly enhanced by an extracellular signal-regulated kinase 1/2-dependent mTOR

66 ed activation of cardiac fibroblasts through extracellular signal-regulated kinase 1/2-dependent phos

67 emic retinopathy selectively activates GPR81-extracellular signal-regulated kinase 1/2-Norrin signali

68 els of phosphorylated IkappaBalpha, Akt, and extracellular signal-regulated kinase 1/2; nuclear trans

69 carcinoma (HCT116) cells treated with H2O2, extracellular signal-regulated kinases 1 and 2 (ERK1/2)

70 Here, we show that sustained activation of extracellular signal-regulated kinases 1 and 2 (ERK1/2)

71 ses 1 and 2 (MNK1 and MNK2) are activated by extracellular signal-regulated kinases 1 and 2 (ERK1/2)

72 activation of phosphoinositide 3-kinase and extracellular signal-regulated kinases 1 and 2 by Gbetag

73 Abnormal regulation of extracellular signal-regulated kinases 1 and 2 has been

74 ated kinase 1 (MSK1), a downstream target of extracellular signal-regulated kinases 1 and 2, and an i

75 ion of p38 mitogen-activated protein kinase, extracellular signal-regulated kinases 1 and 2, and Jun

76 a resulted in reduced phosphorylation of the extracellular signal-regulated kinases 1 and 2, enhanced

77 ethyl-D-aspartate receptors or activation of extracellular signal-regulated kinases 1 and 2, or block

78 nic ability, and invasiveness by suppressing extracellular signal-regulated kinases 1/2 (ERK1/2) and

79 eported mediator in vibratory urticaria, and extracellular signal-regulated kinases 1/2 activation wa

80 treated with necrotic bone showed increased extracellular signal-regulated kinases 1/2 and Ikappa ki

81 TZ and lapatinib ability to block extracellular signal-regulated kinases 1/2 and phosphati

82 ase C, and phosphoinositide 3-kinase but not extracellular signal-regulated kinases 1/2 pathways, alo

83 oduction and produced enduring activation of extracellular signal-regulated kinases 1/2 phosphorylati

84 Mechanistically, activation of extracellular signal-regulated kinases 1/2 were selectiv

85 Silencing FAK, but not extracellular signal-regulated kinases 1/2, abrogated th

86 ation of mammalian target of rapamycin, AKT, extracellular signal-regulated kinases 1/2, phosphatase

87 tion while reducing fibroblast growth factor/extracellular signaling-regulated kinase 1/2 activity in

88 deficiencies, as well as phosphorylation of extracellular-signal regulated kinase 1/2 (ERK1/2).

89 2) (COT, MAP3K8) kinase activates the MEK1/2-extracellular-signal regulated kinase 1/2 MAP kinase sig

90 ng alpha-MSH production via CB1R-induced and extracellular-signal-regulated kinase 1/2 activation- an

91 Inhibitors of p38, extracellular-signal-regulated kinases 1/2 (p44/42 MAPK)

92 Key roles were identified for extracellular signal-regulated kinase-1/2, p38alpha kina

93 beta-arrestin recruitment and DHA-dependent extracellular-signal regulated kinase-1/2 (ERK1/2) signa

94 d subsequent beta-arrestin-2 recruitment and extracellular-signal regulated kinase-1/2 activity.

95 The most frequent extracellular signal-regulated kinase 2 (ERK2) mutation

96 ind the nonphosphorylated (inactive) form of extracellular signal-regulated kinase 2 (ERK2) or its do

97 f miR-494 as a result of the inactivation of extracellular signal-regulated kinase 2 (ERK2), in turn

98 cents, phosphorylation of the trkB substrate extracellular signal-regulated kinase 42/44 (ERK42/44) i

99 hanistic studies revealed that activation of extracellular signal-regulated kinase 5 (ERK5) via upreg

100 thrombosis by increasing activation of MAPK extracellular signal-regulated kinase 5 (ERK5), a protei

101 gen-activated protein kinase kinase 5)-ERK5 (extracellular signal-regulated kinase 5) signaling and c

102 nflammatory molecules and activation of ERK (extracellular signal-regulated kinase) 5/p38 pathways.

103 that TRAF1 is required for solar UV-induced extracellular signal-regulated kinase-5 (ERK5) phosphory

104 teraction network, which includes the kinase extracellular signal-regulated kinase 7 (ERK7).

105 -function variant-mediated Ca(2+) influx and extracellular signal-regulated kinase activation in HEK

106 reactive oxygen species production, and p38/extracellular signal-regulated kinase activation in mast

107 growth factor receptor signalling, including extracellular signal-regulated kinase activation, to dri

108 Spine growth required extracellular signal-regulated kinase activation, while

109 sympathetic nerves increase endothelial ERK (extracellular signal-regulated kinase) activity via adre

110 ct of each variant on the activation of ERK (extracellular signal-regulated kinase), AKT (protein kin

111 oncomitant down-regulation of phosphorylated extracellular signal-regulated kinase and myeloid cell l

112 orters, mRNAs, signaling (phosphorylation of extracellular signal-regulated kinase and phospholamban)

113 receptor 2AT4 and induced phosphorylation of extracellular signal-regulated kinases and p38 mitogen-a

114 ERK (extracellular signal-regulated kinase) and mTOR (mechani

115 extracellular signal-regulated kinase kinase-extracellular signal-regulated kinase) and S6K-RPS6 (rib

116 -fold, inactivated the key signaling protein extracellular signal-regulated kinase, and increased apo

117 ormation, possibly through protein kinase B, extracellular signal-regulated kinase, and NF-kappaB pat

118 nsducer and activator of transcription 5 and extracellular signal-regulated kinase, and transforms pa

119 ed B cells-p65, increased phosphorylation of extracellular-signal-regulated kinase, and reduced the e

120 inositol 1,4,5-triphosphate/protein kinase C/extracellular signal-regulated kinase) are major mediato

121 nsducer and activator of transcription 3 and extracellular signal-regulated kinase, as well as format

122 Finally, combined inhibition of the Raf/MAPK/extracellular signal-regulated kinase axis and eIF4E imp

123 Of note, a phosphorylated extracellular signal-regulated kinase+/BCL-XL(+) /myeloi

124 and three mitogen-activated protein kinases (extracellular signal-regulated kinase, c-Jun N-terminal

125 Other synaptic proteins, such as extracellular signal-regulated kinase, calcium/calmoduli

126 cal analysis of the MAP2K1 downstream target extracellular signal-regulated kinase demonstrated its p

127 1P receptor 3 (S1pr3) through Rho kinase and extracellular signal-regulated kinase-dependent pathway.

128 m after acute cocaine administration, via an extracellular-signal regulated kinase-dependent de novo

129 ingly, knockdown of the canonical downstream extracellular signal-regulated kinase did not reproduce

130 ed protein kinase C (PKC) in the cytosol and extracellular signal regulated kinase (ERK) in the cytos

131 Here we address this question for extracellular signal regulated kinase (Erk) signaling, a

132 alized at 24 h, while the phosphorylation of extracellular signal regulated kinase (ERK) was increase

133 actor (FGF) proteins that signal through the extracellular signal regulated kinase (ERK)/mitogen acti

134 Over expression of extracellular signal regulated kinases (ERK) pathway pla

135 Evidence demonstrates that extracellular signal-regulated kinase (ERK 1/2) activati

136 y slightly reduced downstream phosphorylated extracellular signal-regulated kinase (ERK) (pERK) level

137 acid dibutylester and imiquimod showed that extracellular signal-regulated kinase (ERK) 1/2 cascade

138 Inhibiting p38 MAPK or extracellular signal-regulated kinase (ERK) 1/2 MAPK (up

139 APK target gene expression and assessment of extracellular signal-regulated kinase (ERK) 1/2 phosphor

140 y upregulated, but uncoupled from downstream extracellular signal-regulated kinase (ERK) 1/2 signalin

141 R1 by RO5166017 increased phosphorylation of extracellular signal-regulated kinase (ERK) 1/2, and pro

142 hrough the posttranscriptional activation of extracellular signal-regulated kinase (ERK) 5 signaling,

143 ly localized D2R long isoform (D2LR) elicits extracellular signal-regulated kinase (ERK) activation a

144 d the dynamics of protein kinase C (PKC) and extracellular signal-regulated kinase (ERK) activation d

145 ositide 3-kinase (PI3Kgamma) plays a role in extracellular signal-regulated kinase (ERK) activation f

146 ies have suggested that dysregulation in RAS-extracellular signal-regulated kinase (ERK) activation i

147 ctivation of S6K1 during extinction required extracellular signal-regulated kinase (ERK) activation i

148 Aberrant extracellular signal-regulated kinase (ERK) activation v

149 duced two mechanistically distinct phases of extracellular signal-regulated kinase (ERK) activation,

150 ained intracellular calcium mobilisation and extracellular signal-regulated kinase (Erk) activation,

151 p4k4 silencing in ECs enhanced basal Ras and extracellular signal-regulated kinase (Erk) activities,

152 Although deregulation of MEK/extracellular signal-regulated kinase (ERK) activity is

153 l cell clusters display waves of oscillatory extracellular signal-regulated kinase (ERK) activity, wh

154 iated with a sustained increase in cytosolic extracellular signal-regulated kinase (ERK) activity.

155 ) and E-prostanoid receptor (EP) 3, enhanced extracellular signal-regulated kinase (Erk) and c-fos ph

156 o mitogen-activated protein kinases (MAPKs), extracellular signal-regulated kinase (ERK) and c-Jun N-

157 3T cell line and assessing activation of the extracellular signal-regulated kinase (ERK) and JUN N-te

158 e potent in inhibition of phosphorylation of extracellular signal-regulated kinase (ERK) and of cell

159 well as downstream pathways including STAT5, extracellular signal-regulated kinase (Erk) and p38.

160 Extracellular signal-regulated kinase (ERK) and protein

161 xin-1 deficient B cells to the activation of extracellular signal-regulated kinase (ERK) and signal t

162 rosarcoma cells naturally expressing mutated extracellular signal-regulated kinase (ERK) antigen, the

163 DNA damage-mediated activation of extracellular signal-regulated kinase (ERK) can regulate

164 It recruits and regulates activity of an extracellular signal-regulated kinase (ERK) cascade.

165 lu5-scaffolding protein Homer2 and activated extracellular signal-regulated kinase (ERK) in an adapti

166 es cell proliferation and phosphorylation of extracellular signal-regulated kinase (ERK) in NF1 (-/-)

167 es cell proliferation and phosphorylation of extracellular signal-regulated kinase (ERK) in NF1(-/-)

168 by combined treatment with rapamycin and an extracellular signal-regulated kinase (ERK) inhibitor.

169 Preclinical studies suggest that extracellular signal-regulated kinase (ERK) inhibitors a

170 D8931, identified multiple components of the extracellular signal-regulated kinase (ERK) mitogen-acti

171 Mechanistically, LMP1 triggered the extracellular signal-regulated kinase (ERK) pathway and

172 The extracellular signal-regulated kinase (ERK) pathway is a

173 s report a fascinating phenotype whereby the extracellular signal-regulated kinase (ERK) pathway regu

174 and potently inhibited the pro-proliferative extracellular signal-regulated kinase (ERK) pathway; to

175 lic, vascular endothelial growth factor, and extracellular signal-regulated kinase (ERK) pathways are

176 omal signaling by protein kinase C (PKC) and extracellular signal-regulated kinase (ERK) pathways med

177 and migration of human keratinocytes through extracellular signal-regulated kinase (ERK) phosphorylat

178 f the mitogen-activated protein (MAP) kinase extracellular signal-regulated kinase (ERK) prevents ste

179 sponsive and oncogenically activated protein extracellular signal-regulated kinase (ERK) promotes mot

180 Appropriate activation of the Ras/extracellular signal-regulated kinase (ERK) protein sign

181 ellular signal-regulated kinase kinase (MEK)/extracellular signal-regulated kinase (ERK) scaffold, ki

182 ow that miR-431 overexpression activates Ras/extracellular signal-regulated kinase (Erk) signaling an

183 d by Jun N-terminal protein kinase (JNK) and extracellular signal-regulated kinase (ERK) signaling at

184 Deregulated extracellular signal-regulated kinase (ERK) signaling dr

185 ventral tegmental area via modulation of the extracellular signal-regulated kinase (ERK) signaling pa

186 and mitogen-activated protein kinase (MAPK)/extracellular signal-regulated kinase (ERK) signaling pa

187 tations in the genes involved in the RAF/MEK/extracellular signal-regulated kinase (ERK) signaling pa

188 protein 2 (SREBP2) through activation of the extracellular signal-regulated kinase (ERK) signaling pa

189 es via the c-Jun N-terminal kinase (JNK) and extracellular signal-regulated kinase (ERK) signaling pa

190 uclear factor (NF) kappaB signaling, whereas extracellular signal-regulated kinase (ERK) signaling wa

191 uced endocytosis is associated with impaired extracellular signal-regulated kinase (ERK) signaling, d

192 11-kDa and Grb2 interaction disrupts extracellular signal-regulated kinase (ERK) signaling, w

193 activation by GPCRs and CAMs, giving rise to extracellular signal-regulated kinase (ERK) signaling.

194 ge interactions in driving cAMP, calcium, or extracellular signal-regulated kinase (ERK) signaling.

195 Fibroblast growth factor (FGF)-extracellular signal-regulated kinase (ERK) signalling i

196 disruption of the transcriptional control of extracellular signal-regulated kinase (ERK) signalling.

197 Here, we adapt the first-generation KTR for extracellular signal-regulated kinase (ERK) to allow eas

198 of NF-kappaB, c-Jun N-terminal kinase (JNK), extracellular signal-regulated kinase (ERK), and Akt (oc

199 bated with inhibitors of MEK (trametinib) or extracellular signal-regulated kinase (ERK), and some ce

200 ased mitogen-activated protein kinase (MAPK)/extracellular signal-regulated kinase (ERK), mTOR, and p

201 ulin signaling/glucose homeostasis (ie, Akt, extracellular signal-regulated kinase (ERK), P70S6K), as

202 n of mitogen-activated protein kinase (MAPK)/extracellular signal-regulated kinase (ERK), PI3K/AKT, a

203 gnalling pathways such as those regulated by extracellular signal-regulated kinase (ERK), protein kin

204 ing leukocyte protein of 76 kDa (SLP76), and extracellular signal-regulated kinase (Erk), were enhanc

205 e required for host immune response, whereas extracellular signal-regulated kinase (ERK), which is es

206 we investigated the DA D1 receptor (D1R) and extracellular signal-regulated kinase (ERK)-cAMP-respons

207 amide, KGF-pretreated mice also had apparent extracellular signal-regulated kinase (ERK)-driven proli

208 AF binding potential, and therefore altering extracellular signal-regulated kinase (ERK)-mediated PKM

209 ndritic cells (DCs) is triggered by IL-6 and extracellular signal-regulated kinase (ERK)-mitogen-acti

210 ciated herpesvirus (KSHV) requires sustained extracellular signal-regulated kinase (ERK)-p90 ribosoma

211 FGF19 activates the mTORC1-p70S6K and extracellular signal-regulated kinase (Erk)-p90RSK pathw

212 (psMEK) short-circuits the highly conserved Extracellular Signal-Regulated Kinase (ERK)-signaling ca

213 a to significantly reduce phosphorylation of extracellular signal-regulated kinase (ERK).

214 integrin-mediated phosphorylation of Src and extracellular signal-regulated kinase (ERK).

215 es apoptosis through increased activation of extracellular signal-regulated kinase (ERK).

216 rylation of downstream MAPK/ERK kinase (MEK)/extracellular signal-regulated kinase (ERK).

217 ownregulating the phosphorylation of MEK and extracellular signal-regulated kinase (ERK).

218 3 phosphorylation on sites phosphorylated by extracellular signal-regulated kinase (ERK).

219 , p21-activated protein kinases (PAK1/2) and extracellular signal-regulated kinase (ERK)/C-Jun N-term

220 n development and to differentially regulate extracellular signal-regulated kinase (ERK)/mitogen-acti

221 of epidermal growth factor receptor (EGFR), extracellular signal-regulated kinase (ERK)1/2 or a TFF2

222 ses, mitogen-activated protein kinase [i.e., extracellular signal-regulated kinase (ERK)], and p70S6

223 y inhibitors of the prolyl isomerase Pin1 or extracellular signal-regulated kinases (ERK) 1/2 or by p

224 The Ras/PI3K/extracellular signal-regulated kinases (ERK) signaling n

225 (JNK), the Axl receptor tyrosine kinase and extracellular signal-regulated kinases (ERK).

226 induce specific responses through a common, extracellular-signal regulated kinase (ERK)-dependent ca

227 r of mitogen-activated protein kinase (MAPK)/extracellular-signal-regulated kinase (ERK) (MEK) 1/2, w

228 se protein, which binds and dephosphorylates extracellular-signal-regulated kinase (ERK), leading to

229 Extracellular-signal-regulated kinases (ERK) 1 and 2 reg

230 the mitogen-activated protein (MAP) kinase (extracellular signal-regulated kinase [ERK]) signaling c

231 ind that the proteinase ADAM17 activates the extracellular signal-regulated kinases (ERK1/2) pathway

232 Here, we show that extracellular signal-regulated kinases (ERK1/2) respond

233 Fibroblast growth factor-extracellular signal-regulated kinase (FGF -ERK) signall

234 ession by activating a pathway that involves extracellular-signal-regulated kinase, IL-6 and the tran

235 cells was associated with phosphorylation of extracellular signal-regulated kinases, implying externa

236 causally linked with excessive activation of extracellular signal-regulated kinases in striatal neuro

237 ted by MEK (mitogen-activated protein kinase/extracellular signal-regulated kinase) inhibition or c-J

238 Acquired BRAF/MAPK/extracellular signal-regulated kinase inhibitor resistan

239 nib and the mitogen-activated protein kinase/extracellular signal-regulated kinase inhibitor selumeti

240 ed BRAF and mitogen-activated protein kinase/extracellular signal-regulated kinase inhibitor treatmen

241 phosphatase receptor type J (PTPRJ), a known extracellular signal-regulated kinase inhibitor.

242 s and Pam3Cys led to phosphorylation of ERK (extracellular signal-regulated kinase), JNK, and p38 mit

243 as EGFR or mitogen-activated protein kinase/extracellular signal-regulated kinase kinase (MEK)/ERK i

244 that the Ras/Raf/mitogen-activated protein, extracellular signal-regulated kinase kinase (MEK)/extra

245 anomas frequently develop resistance to MAPK/extracellular signal-regulated kinase kinase inhibitors

246 y niches counteracts combined BRAF/MEK (MAPK/extracellular signal-regulated kinase kinase) inhibitor

247 6 on both MEK-ERK (mitogen-activated protein/extracellular signal-regulated kinase kinase-extracellul

248 MAPK pathways in yeast and in the mammalian extracellular signal-regulated kinase MAPK pathway.

249 kout, while mitogen-activated protein kinase/extracellular signal-regulated kinase (MAPK/ERK) and non

250 vation of a mitogen-activated protein kinase/extracellular signal-regulated kinase (MAPK/ERK) negativ

251 ppaB kinase (IKK), mitogen-activated protein extracellular signal-regulated kinase (MEK), and Jun N-t

252 MP1 protein levels through activation of the extracellular signal-regulated kinase mitogen-activated

253 and a synthetic lethal interaction with the extracellular signal-regulated kinase mitogen-activated

254 The RAS-ERK/MAPK (RAS-extracellular signal-regulated kinase/mitogen-activated

255 ncrease in phosphorylation and activation of extracellular signal-regulated kinase/mitogen-activated

256 inal kinase (JNK) and c-Jun signals, but not extracellular signal-regulated kinase or Akt pathway act

257 -containing phosphatase [p-SHP2] and phospho-extracellular signal-regulated kinase [p-ERK]) is associ

258 ACD-induced cytoskeletal collapse activated extracellular signal-regulated kinase, p38, and c-Jun am

259 levels for the phosphorylated forms of AKT, extracellular signal-regulated kinase, p38, STAT1, and S

260 ls a new functional role for cocaine-induced extracellular signal-regulated kinase pathway independen

261 to enhance the efficacy of BRAF-MAPK kinase-extracellular signal-regulated kinase pathway inhibition

262 rvival signaling pathways, including the MEK-extracellular signal-regulated kinase pathway.

263 ), such as high expression of phosphorylated extracellular signal-regulated kinase (pERK) and reduced

264 the neuronal activity marker phosphorylated extracellular signal-regulated kinase (pERK) identified

265 Additionally, the ratio of activated extracellular signal-regulated kinases (pERK) or pAkt to

266 of K-Ras effectors, including phosphorylated extracellular signal-regulated kinase, phosphorylated pr

267 cillatory magnitudes via modulation of local extracellular signal-regulated kinase phosphorylation (p

268 stress (S-SDS) induces D1 receptor-mediated extracellular signal-regulated kinase phosphorylation an

269 Furthermore, miR-4443 regulated extracellular signal-regulated kinase phosphorylation an

270 ression in primary OA chondrocytes inhibited extracellular signal-regulated kinase phosphorylation in

271 vemurafenib (480 mg/d) completely abrogated extracellular signal-regulated kinase phosphorylation of

272 the amygdala [CeA]) PACAP immunoreactivity, extracellular signal-regulated kinase phosphorylation, a

273 FSTL1 blocks Wnt7a-mediated repression of extracellular signal-regulated kinase phosphorylation, e

274 s phospho-Ser10-histone H3 without modifying extracellular-signal regulated kinase phosphorylation in

275 /calmodulin-dependent protein kinase II, and extracellular signal-regulated kinase, play key roles in

276 reased phosphorylation level of both Src and extracellular signal regulated kinase proteins and with

277 ibrosarcoma/mitogen-activated protein kinase/extracellular signal-regulated kinase (Raf/MEK/ERK) path

278 The extracellular signal-regulated kinase-ribosomal S6 PK-ph

279 hibition of mitogen-activated protein kinase/extracellular signal-regulated kinase signaling 6 hours

280 a role of this holoenzyme in suppression of extracellular signal-regulated kinase signaling and prot

281 ndocytosis to block endosomal PACAP receptor extracellular signal-regulated kinase signaling attenuat

282 Notably, inhibition of Raf/MAPK/extracellular signal-regulated kinase signaling decrease

283 nd enhance or diminish AKT Ser/Thr kinase or extracellular signal-regulated kinase signaling in a bia

284 se/AKT, and mitogen-activated protein kinase/extracellular signal-regulated kinase signaling in mutat

285 Instead, enhanced phosphorylated extracellular signal-regulated kinase signaling in Wolff

286 e of knockout mice, suggesting that impaired extracellular signal-regulated kinase signaling mediated

287 The mitogen-activated protein kinase/extracellular signal-regulated kinase signaling pathway

288 g family, pyrin domain-containing-3, and p38/extracellular signal-regulated kinase signaling pathways

289 ired to maintain normal cardiac function via extracellular signal-regulated kinase signaling.

290 NF release and tropomyosin receptor kinase B-extracellular signal-regulated kinase signaling.

291 nd clearance by alveolar macrophages through extracellular signal-regulated kinase signaling.

292 inositol-3'-kinase/protein kinase B and KRAS/extracellular-signal-regulated kinase signaling pathways

293 B cells from tolerant recipients had reduced extracellular signal-regulated kinase signalling after B

294 eton by dephosphorylating eplin at two known extracellular signal-regulated kinase sites, serine 362

295 epithelial cells; elevates protein kinase A, extracellular signal-regulated kinases, SMAD and signal

296 atidylinositol 3-kinase-Akt, Ras-Raf-1, MEK1/extracellular signal-regulated kinase, sphingolipid, and

297 , A61603 activation of cardioprotective ERK (extracellular signal-regulated kinase) was markedly impa

298 Mechanistically, reactive oxygen species and extracellular signal-regulated kinase were found to medi

299 tivates the mitogen-activated protein kinase extracellular-signal-regulated kinase, which then direct

300 ular, disruption of mGlu5 phosphorylation by extracellular signal-regulated kinase within this brain