ライフサイエンスコーパス: extraction ratio

1 sure of rosuvastatin by reducing its hepatic extraction ratio.

2 ystemic vascular resistance index and oxygen extraction ratio.

3 pressed as the (11)C-verapamil radioactivity extraction ratio ((11)C-verapamil brain distributional c

4 ore oxygen than those perfused with RBCs (O2 extraction ratio 13.75 vs 9.43 % x10 per gram of tissue,

5 d with nine model drugs, the predicted liver extraction ratio, a measure of efficiency of drug remova

6 -3.7% (-4.4% to -3.0%) (p < 0.01) for oxygen extraction ratio; and 4.9 mL/min/m (0.9-9.0 mL/min/m) (p

7 f excitation light and the increase of light extraction ratio by surface roughening structures.

8 jection fraction, cardiac output, and oxygen extraction ratio declined in these animals.

9 nfidence interval: 0.07 to 1.24), but the O2 extraction ratio did not change (-1.0%; 95% confidence i

10 Ten compounds (11%) had an IE extraction ratio (E(IE), the ratio of IE clearance over

11 ibition, hERG inhibition, and rat microsomal extraction ratio (ER).

12 o2 level (</=75%) corresponding to an oxygen extraction ratio greater than 0.36.

13 se excess; oxygen delivery, consumption, and extraction ratio; hematocrit; hemoglobin; and urine outp

14 crit in the latter and an increase in oxygen extraction ratio in the former.

15 However, the oxygen extraction ratio in the liver of sham animals was the hi

16 e flow rate, which was consistent with a low extraction ratio in the perfusion model.

17 ine whether blood flow, DO2, VO2, and oxygen extraction ratio in various organs are differentially al

18 approximated tissue blood flow (Q); that is, extraction ratio (K1/Q) was approximately 1, indicating

19 xygen delivery was higher, and tissue oxygen extraction ratio lower, in RIPC + HS animals.

20 Oxygen extraction ratios (O2ER) and oxygen consumption values w

21 .35 L/h, respectively, with calculated human extraction ratio of 0.153 and terminal half-life of 31.2

22 ion (0.11-1.30 microg/kg/hr) had a pulmonary extraction ratio of 0.69 +/- 0.17.

23 ye transit time and slight increase in renal extraction ratio of paraaminohippurate suggesting a rise

24 o of PGE1 of 0.78 +/- 0.12, (2) a splanchnic extraction ratio of PGE1 of 0.54 +/- 0.23, and (3) level

25 microg/kg/hr) demonstrating: (1) a pulmonary extraction ratio of PGE1 of 0.78 +/- 0.12, (2) a splanch

26 mities and kidneys and increasing the oxygen extraction ratio of the splanchnic bed.

27 After reperfusion, significantly lower extraction ratios of most substrates were found, as well

28 icular afterload, but, instead, increased O2 extraction ratio (p < 0.02) with a consequent fall in Sv

29 ution correlated with the improvements in O2 extraction ratio (P = 0.022).

30 delivery index and consumption index, oxygen extraction ratio, plasma lactate, hemoglobin), blood gas

31 Estimated cerebral glucose extraction ratios taking into account an increased cereb

32 account the unknown para-aminohippuric acid extraction ratio, the RPF rate was calculated to have li

33 ned, and systemic oxygen delivery (Do2I) and extraction ratio were calculated.Measurements were made

34 Oxygen delivery, consumption, and extraction ratio were determined.

35 Systemic and regional DO2, VO2, and oxygen extraction ratio were then calculated.

36 The calculated extraction ratios were 0.104, 0.363, 0.231 and 0.591 for

37 uman MLP-corrected Cl/F, terminal half-life, extraction ratios were in close proximity to the observe

38 relates significantly better to the observed extraction ratio when using the dynamic free fraction (f

39 stability, intrinsic clearance, and hepatic extraction ratios with T1/2 > 247 min, CLint < 7 muL/min