ライフサイエンスコーパス: extragenic

1 erference effect occurred through a dominant extragenic agent.

2 All suppressor mutations are extragenic and map to either rpoB or rpoC, which encode

3 ative function, overexpressing sur-5 from an extragenic array partially suppresses the Multivulva phe

4 We identified one extragenic ced-4 suppressor, which has a mutation in the

5 pendent haploblocks of FGF1 and the adjacent extragenic chromosomal regions.

6 ever, gamma(1)34.5 deletion mutants, with an extragenic compensatory mutation, inhibit PKR activity b

7 Extragenic compensatory mutations, which partially suppr

8 Here, we determine how two extragenic CREs that are prominent in epithelial cells i

9 msii contrasts with the upstream [corrected] extragenic crossover site for antigenic variation in Afr

10 The downstream extragenic crossover site in B. hermsii contrasts with t

11 nhancers may use mechanisms that differ from extragenic distal enhancers.

12 l into three classes: intragenic revertants, extragenic dominant suppressors (sup-39), and a single a

13 We isolated extragenic (E) FtsN*-suppressing mutations that restore

14 A and G insertions and sites of partial and extragenic editing in Physarum mitochondrial RNAs, as we

15 factors of myogenesis (MyoD and Myogenin) at extragenic enhancer regions coinciding with RNA synthesi

16 The biological functions of extragenic enhancer RNAs and their impact on disease ris

17 Both extragenic enhancers result in TS behavioral phenotypes

18 We showed previously that intronic and extragenic enhancers, when occupied by specific transcri

19 Environmental and extragenic factors are pivotal determinants of disease p

20 ingle expression site at rates determined by extragenic features of silent loci rather than similarit

21 We show that extragenic GATA switch sites occupied by GATA-2 associat

22 ranslation products from both intragenic and extragenic genomic regions, including peptides derived f

23 idate an algorithm for the identification of extragenic genomic safe harbors (GSH) that can be effici

24 The identification of functional extragenic GSHs thus expands the human genome available

25 Further, we mapped a single extragenic H3K27M suppressor to ubc-20, an E2 ubiquitin-

26 n of the SMF1 gene, which was isolated as an extragenic high-copy suppressor.

27 ssion vector pET23a(+) and examined if these extragenic I-1-Pases could complement the suhB mutation

28 side F3L, suggesting that the suppression is extragenic in nature.

29 The ability to inherit such extragenic information may provide adaptive benefits to

30 lopmental plasticity, genetic accommodation, extragenic inheritance and niche construction.

31 from ATF3 and other AP-1 promoter-associated extragenic loci in injured sensory neurons but are not u

32 tations in the tRNA promoter elements, or in extragenic loci that inhibit RNA polymerase III complex

33 In contrast, at an extragenic locus lacking Pho4-binding sites, methylation

34 agenic single nucleotide polymorphism and an extragenic microsatellite marker are in linkage disequil

35 hanisms participating in pathogenesis and/or extragenic modification of phenotypic expression.

36 1, a genetic screen was employed to identify extragenic modifier mutations of a temperature-sensitive

37 e report here that mutations in gem-4 (gon-2 extragenic modifier) are capable of suppressing loss-of-

38 in-of-function mutations in the gem-1 (gon-2 extragenic modifier) locus.

39 rs (one enhancer and one suppressor) and two extragenic modifiers (both enhancers).

40 JSRD and provide a model system for studying extragenic modifiers in JSRD and other ciliopathies.

41 as well as mutations mapping to other genes (extragenic modifiers).

42 via an activation-tagging screen for bri1-5 extragenic modifiers.

43 aG-pspF intergenic region contains a complex extragenic mosaic element, RIB.

44 Furthermore, extragenic motile suppressors which arise in DeltafliX c

45 t viruses can be genetically separated by an extragenic mutation at another site in the viral chromos

46 le revertants possessed an identical, single extragenic mutation to create a partially constitutively

47 studies had undergone diverse intragenic and extragenic mutational events relative to flgS.

48 structure-function analysis of dNSF1 and the extragenic mutations identify gene products with related

49 sed a simple morphological screen to isolate extragenic mutations in six loci, designated ted (for re

50 Extragenic mutations in the acetyltransferase genes SAS2

51 tion of H2BK123 was recently challenged, and extragenic mutations in the strain background used for p

52 We show that dLeuR possesses one or more extragenic mutations that enhance ICP27 transcription, l

53 Extragenic mutations that enhance or suppress E2F activi

54 Two Arabidopsis thaliana extragenic mutations that suppress NaCl hypersensitivity

55 fic to phytochrome A (phyA), we screened for extragenic mutations that suppress the morphological phe

56 Three recessive extragenic mutations that suppress trm6-504 mutant pheno

57 We identified and characterized 14 extragenic mutations that suppressed the dominant egg-la

58 y on glycerol, but growth can be enhanced by extragenic mutations, termed glycerol suppressors, in th

59 can be dominantly enhanced and suppressed by extragenic mutations.

60 us-control regions, represent major sites of extragenic noncoding transcription.

61 zed revertants of shy1 null mutants carrying extragenic nuclear suppressor mutations.

62 AIMIE detected repeated extragenic palindrome (REP) elements, CRISPR repeats, up

63 eotide (nt) sequence containing a repetitive extragenic palindrome (REP) from the chloramphenicol ace

64 ed a 389-kb interchromosomal insertion at an extragenic palindrome site at Xq27.1 that completely cos

65 Finally, mutagenesis of the repetitive extragenic palindromic (REP) elements within the yqjH-yq

66 Isolates were fingerprinted using repetitive extragenic palindromic (REP) polymerase chain reaction a

67 using degenerate primers based on repetitive extragenic palindromic (REP) sequences (REP-PCR) were co

68 Repetitive extragenic palindromic (REP) sequences are highly struct

69 epending largely on the number of repetitive extragenic palindromic (REP) sequences present.

70 genetic diversity was measured by repetitive extragenic palindromic (REP)-PCR fingerprinting.

71 s, derived from the gram-negative repetitive extragenic palindromic element, were also applied to 18

72 Repetitive extragenic palindromic PCR (rep-PCR) is less time-consum

73 sis, colony size, colony texture, repetitive extragenic palindromic PCR (rep-PCR) pattern, and cellul

74 Repetitive extragenic palindromic PCR (REP-PCR) separated 167 isola

75 trains by growth characteristics, repetitive extragenic palindromic PCR fragment pattern, and some bi

76 terized (sequencing of bla genes, repetitive extragenic palindromic polymerase chain reaction, pulse-

77 ophoresis (PFGE), ribotyping, and repetitive extragenic palindromic sequence-based PCR (rep-PCR) were

78 the 16S ribosomal DNA (rDNA) and repetitive extragenic palindromic sequence-PCR (REP-PCR) to charact

79 Repetitive extragenic palindromic sequences (REPs) are a class of e

80 s are structurally similar to the repetitive extragenic palindromic sequences of Escherichia coli, al

81 Over 375 repetitive extragenic palindromic sequences unique to Pss B728a whe

82 sed-field gel electrophoresis and repetitive extragenic palindromic-PCR), multilocus sequence type (M

83 MS isolates were genotyped by repetitive extragenic palindromic-polymerase chain-reaction (rep-PC

84 Enterobacteriaceae were typed by repetitive extragenic, palindromic PCR and pulsed-field gel electro

85 ailable evidence suggests that the two short extragenic regions at the genomic termini, the 3' leader

86 and flanked by the 3' leader and 5' trailer extragenic regions of genomic RNA.

87 ced in pol II-coding sequences compared with extragenic regions or inactive loci.

88 e chromatin domain including both intra- and extragenic regions.

89 These results indicate that GATA-2-bound extragenic regulatory elements recruit Pol II, GATA-1 bi

90 One recessive, red light-specific extragenic revertant, designated red1, was isolated.

91 An extragenic second-site suppressor of the mutant DNA-bind

92 de evidence for germ line transmission of an extragenic sequence-specific silencing factor and implic

93 Extragenic sequences in genomes, such as microRNA and CR

94 palindromic sequences (REPs) are a class of extragenic sequences, which form nucleotide stem-loop st

95 ses processive transcription at thousands of extragenic sites in mammalian genomes.

96 In contrast, at extragenic sites of transcription, which typically lack

97 Using HIS3 and lacZ as reporters, extragenic spontaneous recessive mutations that allowed

98 Previous studies have demonstrated extragenic suppression in the PBDs, but the phenotypes o

99 Extragenic suppressor analysis identified Zip1, a bZIP (

100 A high-copy extragenic suppressor gene, designated DBP4 (DEAD box pr

101 ave now cloned the sudD gene, another of the extragenic suppressor genes of the bimD6 mutation.

102 Extragenic suppressor mutants of the chemotaxis-impaired

103 Spontaneous extragenic suppressor mutants that arose in the triple m

104 that expresses CL04 resulted in selection of extragenic suppressor mutants that grew efficiently usin

105 other site in the viral chromosome; (ii) the extragenic suppressor mutation does not affect neuroviru

106 t to wild-type phenotypes suggesting that an extragenic suppressor mutation is able to overcome the l

107 Although this virus contains an extragenic suppressor mutation that confers enhanced gro

108 A spontaneous extragenic suppressor mutation that overcame the stage I

109 Extragenic suppressor mutations occur in several genes e

110 A novel genetic scheme allowed us to isolate extragenic suppressor mutations that restored mutant Omp

111 In addition, we have isolated four extragenic suppressor mutations that suppress the long-f

112 Two extragenic suppressor mutations were identified as mappi

113 re then used to identify both intragenic and extragenic suppressor mutations.

114 The sel-1 gene was identified as an extragenic suppressor of a lin-12 hypomorphic mutant.

115 RSS1 is the first reported high-copy extragenic suppressor of a mutant nucleoporin.

116 Sgd1p: One allele of sgd1 acts as a dominant extragenic suppressor of a mutation in a predicted RNA-b

117 receptor kinase (BRL1) was identified as an extragenic suppressor of a weak bri1 allele, bri1-5, in

118 ila lacking Suppressor of Fused (Su(fu)), an extragenic suppressor of fu, indicating that Su(fu) is n

119 An allele-specific extragenic suppressor of mglA8, named mas815 (mglA8 supp

120 Here we show that an extragenic suppressor of Raf, Su(Raf)1, encodes a Drosop

121 We previously cloned the sudA gene, an extragenic suppressor of the heat-sensitive bimD6 mutati

122 f RSS1 (Rat Seven Suppressor) as a high-copy extragenic suppressor of the rat7-1 temperature-sensitiv

123 In this study, we demonstrate that an extragenic suppressor of the temperature sensitivity of

124 rvation as a basis for genetic selection, an extragenic suppressor of Tus-mediated arrest of DNA repl

125 We carried out an extragenic suppressor screen in PA103DeltafimX bacteria

126 es a 5'-3' exonuclease, was identified as an extragenic suppressor that increases the half-life of rh

127 ear to form colonies only after acquiring an extragenic suppressor(s).

128 tic interaction, and are rescued by the same extragenic suppressor, Su(DTS)-1.

129 ions were alpha1-tubulin pseudorevertants or extragenic suppressors (the majority alter the beta1-tub

130 se essential cellular functions, we selected extragenic suppressors and identified rimJ as a high-cop

131 We identified nine extragenic suppressors as alleles of MAS2 (MORPHOLOGY OF

132 nce of an exogenous reductant and accumulate extragenic suppressors at a high frequency.

133 (iv) All extragenic suppressors contained an R229-->L mutation in

134 ure-sensitive mutations in the xcpT gene and extragenic suppressors for one of the mutants.

135 Two extragenic suppressors have been mapped to a groEL segme

136 uppressor decreased the general influx while extragenic suppressors increased the efflux of TolC-AcrA

137 Extragenic suppressors map to an unlinked gene, flhB, wh

138 Four of the mutants yielded extragenic suppressors mapping to the FlaII or FlaIIIB r

139 SUF13 and SUF14 genes were identified among extragenic suppressors of +1 frameshift mutations.

140 s within the motor, we attempted to identify extragenic suppressors of 31 dominant, plasmid-borne all

141 suppressor of divK) alleles were isolated as extragenic suppressors of a cold-sensitive divK mutation

142 A screen for extragenic suppressors of a cold-sensitive ydr1 (ydr1(cs

143 involved in thermotolerance, we screened for extragenic suppressors of a dominant-negative allele of

144 is consistent with genetic studies in which extragenic suppressors of a mutant TolC strain were foun

145 In a screen for extragenic suppressors of a silencing defective rap 1s h

146 exocyst degradation pathway, we screened for extragenic suppressors of a temperature-sensitive fissio

147 netic screen in Saccharomyces cerevisiae for extragenic suppressors of a temperature-sensitive npl4 a

148 We isolated spontaneous extragenic suppressors of a temperature-sensitive, letha

149 n vivo, we performed a genetic selection for extragenic suppressors of a yeast TBP mutant that exhibi

150 asmA mutations were isolated as extragenic suppressors of an OmpF assembly mutant, OmpF3

151 We have isolated seven cold-sensitive extragenic suppressors of bimD6 heat sensitivity that re

152 UPF2, UPF3, and ICK1, were represented among extragenic suppressors of ctf13-30.

153 Sequenced spontaneous extragenic suppressors of dksA polyauxotrophy are freque

154 f the switch-motor complex, we have isolated extragenic suppressors of dominant and partially dominan

155 A search for extragenic suppressors of gal4D identified recessive mut

156 Extragenic suppressors of hls1 were identified as mutati

157 ntify these factors, we isolated spontaneous extragenic suppressors of hsp82-deltaHSE1, an allele of

158 Extragenic suppressors of MMM1 deletion mutants partiall

159 The isolation of extragenic suppressors of one of these spt3 mutations ha

160 ied a selection procedure for intragenic and extragenic suppressors of orange-light-inverted mutants

161 kismet (kis) was identified in a screen for extragenic suppressors of Polycomb (Pc) and subsequently

162 Here we show that extragenic suppressors of the 3' stem mutation map to th

163 ed in these processes, we have isolated four extragenic suppressors of the A. nidulans nimX2(cdc2) te

164 unction with bimD, we conducted a screen for extragenic suppressors of the bimD5 and bimD6 mutations.

165 e, we performed a genetic screen to identify extragenic suppressors of the cold-sensitive growth defe

166 we describe the isolation of 12 spontaneous extragenic suppressors of the doa4-1 mutation; these inv

167 We performed a screen for extragenic suppressors of the nimA1 allele and isolated

168 otoprotection, we isolated and characterized extragenic suppressors of the npq1 lor1 double mutant of

169 entifying interacting proteins, a screen for extragenic suppressors of the temperature-sensitive nudC

170 Cloning of extragenic suppressors of the ts allele of YPT6 has reve

171 We isolated extragenic suppressors of the Y68A plaque formation defe

172 trichome branch initiation, we screened for extragenic suppressors of the zwi-3 mutation and isolate

173 In a genetic screen we have identified extragenic suppressors of this gain-of-function mutant.

174 Two extragenic suppressors of TolC(R367H), mapping in the re

175 mutation, we isolated a number of intra- and extragenic suppressors that increase in vivo GroE chaper

176 Delta(lapA lapB) mutant accumulated extragenic suppressors that mapped either to lpxC, waaC,

177 e TolC mutant (TolCP246R,S350C), we isolated extragenic suppressors that mapped within the acrRAB loc

178 Extragenic suppressors that regain the ability to synthe

179 otype in soft agar at 24 degrees C contained extragenic suppressors that were null mutations mapping

180 Ten recessive, extragenic suppressors were identified.

181 Multicopy extragenic suppressors were selected in strains carrying

182 Dosage and extragenic suppressors were selected.

183 Extragenic suppressors with restored capacity to replica

184 ly poor flagellation and swarming, generated extragenic suppressors, all of which mapped to flgB, one

185 ew bld2 alleles and three partially dominant extragenic suppressors, rgn1-1, rgn1-2, and rgn1-3.

186 revertants of priA2::kan strains that carry extragenic suppressors.

187 The remaining eex alleles were extragenic to pol2-4.

188 The prevalence of suppressors extragenic to the Pol epsilon gene suggests that factors

189 ation, effectively distinguishing genic from extragenic transcription and enabling normal gene expres

190 suggests a putative functional role for the extragenic transcription observed at the beta-globin and

191 ficient termination at Restrictor-controlled extragenic transcription units involves the recruitment

192 icient termination of processive, long-range extragenic transcription.

193 dently from, Restrictor to dampen processive extragenic transcription.

194 gation eliminated the synthesis of genic and extragenic transcripts and eliminated Pol II from the be

195 A DNase I hypersensitive site and extragenic transcripts at IFNgCNS2 correlated positively