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1   We did intention-to-treat analyses with no extrapolation.
2 d in vitro to in vivo biotransformation rate extrapolation.
3 l responses proposed to contribute to motion extrapolation.
4 pic anchors for in vitro to in vivo toxicity extrapolation.
5 sound, but not the post hoc ergo procter hoc extrapolation.
6 dose rabbit data and then conduct a low-dose extrapolation.
7 ate forecasts, risk analysis, and geographic extrapolation.
8 nding model reduces the uncertainty in these extrapolations.
9 stic of Earth's core is higher than previous extrapolations.
10 were estimated based on predefined modelling extrapolations.
11 least in the order of 10(15) M(-1) (based on extrapolation), 3 orders of magnitude larger than that o
12 rns of variability can lead to more rational extrapolations across species and improved protectivenes
13                     Furthermore, exponential extrapolation allowed prediction of the new PetCO2 equil
14 rogeneity of some HIV-1 Env proteins and, by extrapolation, also vaccine immunogens from other pathog
15 l strategies and address concerns related to extrapolation and developmental timelines.
16 effective framework to test in vitro-in vivo extrapolation and holds great promise for predicting tox
17 inal models and may improve in vitro-in vivo extrapolation and prediction of chemical bioaccumulation
18 and understanding the neural basis of motion extrapolation and prediction.
19 bioactivity assays using in vitro-to-in vivo extrapolation and reverse dosimetry.
20                      These data fit previous extrapolations and, combined with new osmolalities from
21 h, and has applications for in vitro-in vivo extrapolation, and prioritization of chemicals in nontar
22 r demand on visual-spatial memory for motion extrapolation, and thus participants did not experience
23                 We apply a mixed rarefaction/extrapolation approach to a global multi-taxa dataset fr
24  (EIAV) as an example, demonstrates a linear extrapolation approach to obtain backbone (15)N spin rel
25                             The "constrained extrapolation" approach generalizes earlier global semie
26                                  Rarefaction/extrapolation approaches can quantify within-habitat bio
27                   For membrane proteins, the extrapolations are fraught with considerable uncertainty
28                                         Such extrapolations are particularly risky when allometry is
29 in uses the fast-OFF cell circuit for target extrapolation as we suggest, the circuit dynamics should
30 nceptually reversing these expansions allows extrapolation backward in time to generate models of pri
31                                              Extrapolation based on expected U.S. transportation ener
32 n actual object reappearance position and an extrapolation based on pre-occlusion velocity.
33                   Accordingly, estimates and extrapolations based on daytime measurements only most l
34 nt coverage among men relied on considerable extrapolation because, in each round, approximately one-
35                                              Extrapolation between centers is difficult and decision-
36                      However, there was poor extrapolation between species and extrapolation was limi
37 terpreting field data and the constraints of extrapolations between species, particularly in terms of
38             However, in many cases, a naive 'extrapolation' between the two species has not succeeded
39 ing subsets of the data, we demonstrate that extrapolation beyond a known part of the landscape is di
40 timation of global species richness requires extrapolation beyond the number of species known.
41 iscovery phase of this pandemic are based on extrapolations by phylodynamic models of HIV-1 genomic s
42 ever, heterogeneous results and cross-tissue extrapolations call for future work.
43 that it exhibits promising interpolation and extrapolation capabilities, superior to the current stat
44                                    Also, the extrapolation capacity of SSDs is largely limited to the
45                              Linear baseline extrapolation, commonly used with absorbance, often fail
46 as a null model, or to perform tasks such as extrapolation, compression and control.
47 al mixture of two within-habitat rarefaction/extrapolation curves to analytically predict biodiversit
48 Corn Belt (as determined using technological extrapolation domains).
49 e methods used and the taxa considered, such extrapolations, especially from small percentages of kno
50                               Second, motion extrapolation explains the spatial shifts observed in se
51 el could enable improved in vitro to in vivo extrapolation for better predictions of human pharmacoki
52 is approach can be used for in vitro-in vivo extrapolations for all 209 PCB congeners.
53          Consonant with predictions, subject extrapolations for test trajectories were consistent wit
54                       Here we show, based on extrapolation from a random sample of land snail species
55 on can be reconstructed via interpolation or extrapolation from adjacent contextual cues by what is n
56 endering management decisions to be based on extrapolation from adult data and the experience of the
57 is challenge as species differences preclude extrapolation from animals.
58 vercome any shortcomings associated with the extrapolation from bulk systems.
59                This would enable more direct extrapolation from controlled dosing studies to estimate
60  of low dose radiation has been estimated by extrapolation from data at higher doses according to the
61 in patients with obesity or IBD are based on extrapolation from general guidelines for antithrombotic
62                         However, a tentative extrapolation from high-income country data suggests glo
63 ssions can be subjective, relying heavily on extrapolation from human-based systems.
64 tary, being mainly derived via bioinformatic extrapolation from other kingdoms.
65                                              Extrapolation from our results suggests that if BSE were
66 ant, subtle, or context-dependent roles, but extrapolation from our results suggests that the majorit
67  because it requires spatial integration and extrapolation from prior knowledge.
68 en not directly available for esophagectomy, extrapolation from related evidence was made.
69                                              Extrapolation from studies in the 1980s suggests that sm
70 for dyslipidemia in this population requires extrapolation from studies performed in older adults.
71                                 Likewise, an extrapolation from the asteroid Vesta would require at l
72                                     Based on extrapolation from the survey sample to the community, w
73                   Models generally assume an extrapolation from the warmer experiments of Merlivat an
74                      However, this is a vast extrapolation from their natural state; development of n
75 omparing observed rates post-intervention to extrapolations from a 24-month pre-intervention trend.
76 iatric psychosis are urgently needed because extrapolations from adult studies might not be implement
77 ng and treating P-NETs in MEN1 patients, and extrapolations from approaches used in patients with non
78 substantially lower than suggested by simple extrapolations from French Polynesia.
79 timates are derived from large spatial-scale extrapolations from highly heterogeneous and often poorl
80 that there are temporal regional changes and extrapolations from one habitat to the next are not poss
81                           The results enable extrapolations from one scale to another, and from one f
82 of its effects in humans is largely based on extrapolations from simple model systems and indirect me
83  are entirely based on theoretical models or extrapolations from small and biased data sets.
84 ilar to published studies based on body-mass extrapolations from studies in adults.
85                              Although motion extrapolation had been proposed a decade earlier (e.g.,
86 tis; however, concerns about such indication extrapolation have been expressed.
87 ural mechanisms that actually perform motion extrapolation have been identified at multiple levels of
88    This estimation of J0 does not involve an extrapolation in length, because it was possible to meas
89 England, United States to overcome issues of extrapolation in novel environments.
90 of allosteric binding sites in AChBP and, by extrapolation, in the human alpha7 nAChR as determined b
91                                              Extrapolations indicated theoretical water-activity mini
92              However, such forecasts require extrapolation into new locations and environments.
93   We also evaluate how the method chosen for extrapolation into nonanalog conditions affects the pred
94                             In vitro-in vivo extrapolation (IVIVE) analyses translating high-throughp
95 nputs to a recently refined in vitro-in vivo extrapolation (IVIVE) model.
96 aqueous nanodispersions; in vitro to in vivo extrapolation (IVIVE) modelling predicts sustained prodr
97 T-S9) and incorporated into in vitro-in vivo extrapolation (IVIVE) models to predict bioconcentration
98 mplex LC/colloidal systems and calculate the extrapolation length of the LCM.
99 rces based on published estimates as well as extrapolations made using these estimates, and lay out p
100                 The individual patient-level extrapolation may need to be solved by a future randomiz
101 converges to support the existence of motion extrapolation mechanisms in the visual system, as well a
102 ly, we have developed and validated a double extrapolation method for predicting retention factors at
103                With the use of the vinylogue extrapolation methodology, resonance effects were determ
104 methods to fill data gaps and on identifying extrapolation methods to derive suitable values for the
105 r basic modeling principles but very diverse extrapolation methods.
106 ere initially argued to challenge the motion extrapolation model of the FLE have since been explained
107 ction accuracy were consistent with a linear extrapolation model that predicted prey position at the
108                                 Based on our extrapolation model, we estimated that the PPV and NPV w
109 bservatory, supplemented by a magnetic field extrapolation model.
110                                           By extrapolation, more than 4.8 million Americans underwent
111                                     However, extrapolation of a regional H2 flux based on the deep go
112 ount of binding molecules allows the precise extrapolation of adhesion rates, from which the concentr
113                                    In linear extrapolation of age-specific geometric means from 2013
114                                              Extrapolation of all three systems to a one-pot tandem b
115                                              Extrapolation of average air-water exchange flux values
116                                By simplistic extrapolation of average weights from rats to humans, a
117 he issues surrounding interchangeability and extrapolation of biosimilars to other disease and patien
118  quantify inhibitory potencies necessary for extrapolation of clinical drug-drug interaction potentia
119 tial for the correct data interpretation and extrapolation of conclusions applicable to the human bra
120 r use to network research, enabling enhanced extrapolation of conclusions from partial data or subset
121                RRP was estimated by the back-extrapolation of cumulative EPSC amplitudes during a tra
122 ions and are component-specific, which makes extrapolation of data difficult to do.
123                                              Extrapolation of data from 13 WWTPs to the nation as a w
124                                        While extrapolation of data from the general population sugges
125                    Our data demonstrate that extrapolation of data on DC biology from one species to
126 tion, precluding quantitative comparison and extrapolation of data.
127            Early global ecology relied on an extrapolation of detailed site-level observations, using
128 nsitive analytical determination allowed the extrapolation of diagnostic information from the minor c
129 rformed and that have been licensed based on extrapolation of efficacy and safety data from other ind
130 al burden of disease, other factors, such as extrapolation of environmental sampling to the entire ex
131                            It was found that extrapolation of experimental data using this function t
132 rs and exhibits unique properties which make extrapolation of findings from the other two subtypes di
133     We use bottom-up (inventory, statistical extrapolation of flux measurements, process-based land a
134 he entire GrIS to SLR have been based on the extrapolation of four major outlet glaciers.
135 entration of antibody was set at 10 IU/mL by extrapolation of functional assay correlates; however, t
136 ecasting of unprecedented events due to poor extrapolation of historical data to unsampled states.
137 s the study populations and end points used, extrapolation of indications, and the confirmatory natur
138 n squared error for MD forecasts with linear extrapolation of indices were 3.58 dB and 31.91 dB(2), a
139                            In order to allow extrapolation of insights gained from murine models to t
140                                              Extrapolation of instantaneous, "snapshot-in-time" measu
141 onductivity of C60, obtained from the linear extrapolation of inverse conductivity vs. inverse length
142                           It facilitates the extrapolation of laboratory experiments to ecologically
143 rstand the functioning of the system and for extrapolation of laboratory findings of stressor impacts
144 fety regulations in structural design or the extrapolation of laboratory results to geophysical field
145                            We evaluated back-extrapolation of land use regression (LUR) models for an
146             The study clearly shows that the extrapolation of LCA results for the circulating fleet a
147 ere we use bottom-up (inventory, statistical extrapolation of local flux measurements, and process-ba
148 ent instead, a modification of the method by extrapolation of logarithmic selectivity coefficients ap
149                                         Back-extrapolation of LUR models appears valid for exposure a
150 he stability is much lower than predicted by extrapolation of measurements made at high denaturant co
151  discussed seven independent approaches: (i) extrapolation of mobility to the zero power, (ii) initia
152            These results suggest that global extrapolation of models based on geographically and taxo
153                                              Extrapolation of models fitted to data at short times to
154  C- and O-glycosylation cautions against the extrapolation of models for S(N)1-type glycosylation wit
155 he activity distribution correctly penalizes extrapolation of models onto structurally different mole
156      The calculated effective dose, based on extrapolation of mouse data, was 0.0218 mSv/MBq, which w
157 action efficiency allowing for more accurate extrapolation of mutational levels in source samples.
158 uss the challenges specific to cross-species extrapolation of neutrophil function during mouse versus
159 inear prediction motion task that emphasized extrapolation of occluded accelerative object motion.
160                                  Preliminary extrapolation of osmolalities of predicted isosmotic sta
161 m the left ventricle, which precludes direct extrapolation of our knowledge of left-sided physiopatho
162 nterfacial free energy of 29(3) mN/m from an extrapolation of our results to the melting temperature.
163                                              Extrapolation of our results to the scenario of a contin
164 e oxygen levels have largely been limited to extrapolation of paleoredox conditions reconstructed fro
165                                  Based on an extrapolation of per capita mass effluent loadings of th
166 mer scientific basis for laboratory to field extrapolation of persistence test results.
167                                              Extrapolation of post-mortem data predicts that a approx
168                                           An extrapolation of potential for CO(2) offset in Europe pr
169 pared with counterfactual scenarios based on extrapolation of pre-SDIL trends.
170 dults and vaccine-induced immunity, or using extrapolation of protection from in-vitro immunoassay re
171  estimated to live 4.4 years on average from extrapolation of recent constant hazard rates beyond the
172 f biological organization and facilitate the extrapolation of results across routes of exposure, dosi
173 ntum observables) can be enhanced through an extrapolation of results from a collection of experiment
174 nd random variation among landscapes, making extrapolation of results from single scale, unreplicated
175 ystem responses, context dependence, and the extrapolation of results.
176 he mobile-phase density, complicating linear extrapolation of retention over longer or shorter column
177 subtypes, particularly in humans; this makes extrapolation of rodent findings to the human situation
178 c model parameters which would allow for the extrapolation of sensitivities to untested species.
179 , such hypotheses have largely relied on the extrapolation of single-cell responses to population res
180 obal mass balance estimates for GICs rely on extrapolation of sparse mass balance measurements repres
181 nferred from various tracers informed by the extrapolation of structures seen in other galaxies.
182          Estimation of annual Rsoil requires extrapolation of survey measurements or gap filling of a
183 ublet levels is not consistent with a simple extrapolation of the calculated relative reaction cross
184 ced the understanding of its photochemistry, extrapolation of the conclusions to the real system requ
185 ncogene in the majority of melanomas, and in extrapolation of the correlation data, interference with
186                                              Extrapolation of the data demonstrated that the detectio
187                                           An extrapolation of the electrochemical and XPS data indica
188  sound velocity, in contrast with a standard extrapolation of the equation of state.
189 ension of supercooled water follows a smooth extrapolation of the IAPWS equation in the supercooled r
190 o be corrected for equilibrium, typically by extrapolation of the loss kinetics of performance refere
191                                              Extrapolation of the Nd and Hf isotopic compositions of
192 unrealistic synthetic solutions, which makes extrapolation of the obtained data to real-world applica
193                                              Extrapolation of the PCs backward for 800 years reveals
194 odiversity results not just from large-scale extrapolation of the process of adaptive radiation in a
195 and diagnosis, these factors allowed for the extrapolation of the risk of dropout.
196                                     However, extrapolation of the transgene data to endogenous L1s su
197 ncrease was less than expected from a linear extrapolation of the trend observed at lower concentrati
198 in covalent inhibitor design, k(inact)/K(I), extrapolation of the underlying parameters, k(inact) and
199 e upwind terrain and the foundations for the extrapolation of the urban wind speed, measurements from
200                          For younger miRNAs, extrapolation of their expression profiles from those of
201 rees N and 40 degrees S, and the first-order extrapolation of these data suggests that the global low
202 cle oxidative phosphorylation cascade, while extrapolation of these data to the exercising muscle pre
203                                          The extrapolation of these findings has enabled us to hypoth
204                                              Extrapolation of these findings to developing countries
205  among household contacts may also limit the extrapolation of these findings to the community setting
206                                     However, extrapolation of these findings towards the in vivo scen
207                                          The extrapolation of these fluxes to other depths, which def
208  clinical use of this agent and has prompted extrapolation of these interpretive categories to other
209 s been demonstrated in bioassay experiments, extrapolation of these laboratory results to natural con
210                                    By linear extrapolation of these quantities from short weathering
211  of connections, a principle that allows the extrapolation of this connectional feature to humans.
212                                              Extrapolation of this overlap suggests that 1.93 x 10(11
213                                              Extrapolation of this success on a national level may fu
214 ialized properties, to the three-dimensional extrapolation of this technique to more complex structur
215 at higher tiers would ultimately require the extrapolation of toxicokinetics and toxicodynamics to un
216 e entity often prompts comparisons with, and extrapolation of treatment approaches from, primary auto
217 t research groups, leading to the paucity of extrapolations of experimental findings into understandi
218 se biases should temper the use of plots for extrapolations of forest dynamics to larger scales, and
219                             Apparently, long extrapolations of helical membrane protein unfolding fre
220                                     Based on extrapolations of NHANES physical examination data to al
221           Shadlen et al's Comment focuses on extrapolations of our results that were not implied or a
222                      These results show that extrapolations of population information based on random
223 ing to the obtained results and regardingthe extrapolations of the maximum residue limits existing fo
224                                     Accurate extrapolations of this type will help planners, transpor
225  higher pressure phase boundaries are either extrapolations or inferred based on indirect evidence.
226 plants has not been shown previously and, by extrapolation, our findings suggest that cysteine-rich p
227                                         Most extrapolation procedures are based on the implicit assum
228 nd European emission inventories using three extrapolation proxies, namely the gross domestic product
229 o develop a quantitative in vitro to in vivo extrapolation (QIVIVE) approach for predicting in vivo a
230 ameters for quantitative in vitro-to-in vivo extrapolations (QIVIVE), but available prediction tools
231 ulations being compared, thus avoiding model extrapolation related to model transfers.
232  of assessment and the challenges of species extrapolation require the development of alternative app
233 be central in the low-dose and cross-species extrapolations required in achieving this goal.
234 ent, and the fundamental assumptions for the extrapolation scheme are fulfilled for this specific cas
235  enabling a formal assessment of widely used extrapolation schemes.
236 e upwind terrain and the foundations for the extrapolation schemes.
237                                          Our extrapolations show that it can evaluate GWASs of 100,00
238 ropose a novel application of the simulation-extrapolation (SIMEX) procedure to address measurement e
239                                              Extrapolation strategies are thus needed to fill in thos
240                                              Extrapolations suggest the smallest 2/3rds of species re
241 62800 (32000-118000) averted infections, and extrapolation suggested that 202000 (98300-407000) infec
242                                           An extrapolation suggests that a dominant stimulatory syste
243 othesis, we trained subjects on a moving dot extrapolation task that makes distinct predictions for t
244 pts at solving this problem involve delicate extrapolations that are highly nonunique and that lack a
245 t for this effect, the (15)N(15)N data allow extrapolations that characterize mantle endmember delta(
246            Based on experimental results and extrapolation, the detection limit is less than 100 pg/m
247 e, and congenital fibrosis syndrome) and, by extrapolation, the hypoplasia or dysgenesis of noncephal
248 (SFTS) is one way to overcome the problem of extrapolation: the response at a given location in a war
249 he electrodes in a pi system is an immediate extrapolation; the theory then predicts that for some sp
250 he vicinity of the replication forks, and by extrapolation, this is also likely to be the case for th
251  energy of stable phases, without relying on extrapolation, thus enabling a formal assessment of wide
252 ions and on simplified models that allow for extrapolation to "infinitely" long polymers provide a so
253 at necessitates revision of the experimental extrapolation to 0 kelvin.
254                  Values of MSE-R(2) for back-extrapolation to 1991 were 0.42-0.45 and 0.52-0.55 for 2
255                 Movement-free imaging allows extrapolation to a three-dimensional map of the specimen
256     However, field research is necessary for extrapolation to agricultural settings.
257                                              Extrapolation to all 12 acute/early participants estimat
258                                              Extrapolation to an ice-free Arctic summer could imply a
259 curring within an environmental chamber, the extrapolation to atmospheric conditions can be assessed.
260 ned at low temperature and their theoretical extrapolation to elevated temperature.
261  that salamanders aim their tongues by using extrapolation to estimate future prey position, thereby
262         The residual component, extracted by extrapolation to films of vanishing thickness and suppor
263 rotoxicity within which these cells operate, extrapolation to human immune function has remained an o
264  quantify uptake and deliver data that makes extrapolation to in vivo studies feasible.
265 few streams on the regional level, hampering extrapolation to larger scales.
266                                              Extrapolation to lifetime therapy yielded the cost per Q
267 r crater chronology and an updated dynamical extrapolation to Mercury, we find that the oldest surfac
268 impact local malaria dynamics is complex and extrapolation to other settings or future times is contr
269                                              Extrapolation to other solid cancers demonstrated highly
270  resulting statistical models also allow for extrapolation to out-of-sample examples to provide a pre
271  at room temperature so that results require extrapolation to physiological temperature.
272  This work is expected to provide a means of extrapolation to pre-clinical or human biodistribution w
273 re conducted under controlled conditions for extrapolation to real situations, we evaluate exposure r
274                                              Extrapolation to real-world exposure scenarios must cons
275                                              Extrapolation to standard conditions gave log(beta0)1:1
276 is reduced by 40 % relative to that found by extrapolation to T=0.
277 xicity is preferably performed in vitro, but extrapolation to the in vivo outcome remains very challe
278 tration alters its speciation, rendering the extrapolation to the low dose exposure chemically incons
279 he nonthermostated capillary part, (v) inter/extrapolation to the nominal temperature, (vi) internal
280 he reliance on a rough figure of 400,000 for extrapolation to the total Yazidi population of Sinjar a
281                                           By extrapolation to the UK as a whole, it is estimated that
282                                 However, for extrapolation to therapeutically relevant doses and plas
283 dependent of the viscosity allows a reliable extrapolation to these objects.
284                                              Extrapolation to transplant patients suggests that the m
285 evidence of allometry, we made morphological extrapolations to infer body dimensions of *O. megalodon
286 glass phase without requiring uncontrollable extrapolations to infinite times or system sizes.
287 ant plant trait distributions will not allow extrapolations to novel community assemblages in future
288 nt gradient profiles, by simple mathematical extrapolation using a known equation, thus offering very
289 D absent PCV7 introduction were estimated by extrapolation using either Poisson regression modeling o
290 ing Cox proportional hazards regression with extrapolation using exponential models.
291 ing Cox proportional hazards regression with extrapolation using exponential models.
292 ing Cox proportional hazards regression with extrapolation using exponential models.
293 as estimated using actual survival data with extrapolation using proportional hazard models adjusting
294           Such rate predictions are based on extrapolations using classical nucleation theory, which
295                     We present out-of-sample extrapolation utilizing semi-supervised ML (OSE-SSL) to
296                         The magnitude of PVA extrapolation varies systematically with target size, sp
297                                         Back-extrapolation was conducted for 2009 and 2001 models to
298 e was poor extrapolation between species and extrapolation was limited to geographic scales smaller t
299 mens for 1- and 2-d protocols based on those extrapolations will result in the expected radiation dos
300                                       Global extrapolation with an empirical modelling approach estim

 
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