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1 We did intention-to-treat analyses with no extrapolation.
2 d in vitro to in vivo biotransformation rate extrapolation.
3 l responses proposed to contribute to motion extrapolation.
4 pic anchors for in vitro to in vivo toxicity extrapolation.
5 sound, but not the post hoc ergo procter hoc extrapolation.
6 dose rabbit data and then conduct a low-dose extrapolation.
7 ate forecasts, risk analysis, and geographic extrapolation.
8 nding model reduces the uncertainty in these extrapolations.
9 stic of Earth's core is higher than previous extrapolations.
10 were estimated based on predefined modelling extrapolations.
11 least in the order of 10(15) M(-1) (based on extrapolation), 3 orders of magnitude larger than that o
12 rns of variability can lead to more rational extrapolations across species and improved protectivenes
14 rogeneity of some HIV-1 Env proteins and, by extrapolation, also vaccine immunogens from other pathog
16 effective framework to test in vitro-in vivo extrapolation and holds great promise for predicting tox
17 inal models and may improve in vitro-in vivo extrapolation and prediction of chemical bioaccumulation
21 h, and has applications for in vitro-in vivo extrapolation, and prioritization of chemicals in nontar
22 r demand on visual-spatial memory for motion extrapolation, and thus participants did not experience
24 (EIAV) as an example, demonstrates a linear extrapolation approach to obtain backbone (15)N spin rel
29 in uses the fast-OFF cell circuit for target extrapolation as we suggest, the circuit dynamics should
30 nceptually reversing these expansions allows extrapolation backward in time to generate models of pri
34 nt coverage among men relied on considerable extrapolation because, in each round, approximately one-
37 terpreting field data and the constraints of extrapolations between species, particularly in terms of
39 ing subsets of the data, we demonstrate that extrapolation beyond a known part of the landscape is di
41 iscovery phase of this pandemic are based on extrapolations by phylodynamic models of HIV-1 genomic s
43 that it exhibits promising interpolation and extrapolation capabilities, superior to the current stat
47 al mixture of two within-habitat rarefaction/extrapolation curves to analytically predict biodiversit
49 e methods used and the taxa considered, such extrapolations, especially from small percentages of kno
51 el could enable improved in vitro to in vivo extrapolation for better predictions of human pharmacoki
55 on can be reconstructed via interpolation or extrapolation from adjacent contextual cues by what is n
56 endering management decisions to be based on extrapolation from adult data and the experience of the
60 of low dose radiation has been estimated by extrapolation from data at higher doses according to the
61 in patients with obesity or IBD are based on extrapolation from general guidelines for antithrombotic
66 ant, subtle, or context-dependent roles, but extrapolation from our results suggests that the majorit
70 for dyslipidemia in this population requires extrapolation from studies performed in older adults.
75 omparing observed rates post-intervention to extrapolations from a 24-month pre-intervention trend.
76 iatric psychosis are urgently needed because extrapolations from adult studies might not be implement
77 ng and treating P-NETs in MEN1 patients, and extrapolations from approaches used in patients with non
79 timates are derived from large spatial-scale extrapolations from highly heterogeneous and often poorl
80 that there are temporal regional changes and extrapolations from one habitat to the next are not poss
82 of its effects in humans is largely based on extrapolations from simple model systems and indirect me
87 ural mechanisms that actually perform motion extrapolation have been identified at multiple levels of
88 This estimation of J0 does not involve an extrapolation in length, because it was possible to meas
90 of allosteric binding sites in AChBP and, by extrapolation, in the human alpha7 nAChR as determined b
93 We also evaluate how the method chosen for extrapolation into nonanalog conditions affects the pred
96 aqueous nanodispersions; in vitro to in vivo extrapolation (IVIVE) modelling predicts sustained prodr
97 T-S9) and incorporated into in vitro-in vivo extrapolation (IVIVE) models to predict bioconcentration
99 rces based on published estimates as well as extrapolations made using these estimates, and lay out p
101 converges to support the existence of motion extrapolation mechanisms in the visual system, as well a
102 ly, we have developed and validated a double extrapolation method for predicting retention factors at
104 methods to fill data gaps and on identifying extrapolation methods to derive suitable values for the
106 ere initially argued to challenge the motion extrapolation model of the FLE have since been explained
107 ction accuracy were consistent with a linear extrapolation model that predicted prey position at the
112 ount of binding molecules allows the precise extrapolation of adhesion rates, from which the concentr
117 he issues surrounding interchangeability and extrapolation of biosimilars to other disease and patien
118 quantify inhibitory potencies necessary for extrapolation of clinical drug-drug interaction potentia
119 tial for the correct data interpretation and extrapolation of conclusions applicable to the human bra
120 r use to network research, enabling enhanced extrapolation of conclusions from partial data or subset
128 nsitive analytical determination allowed the extrapolation of diagnostic information from the minor c
129 rformed and that have been licensed based on extrapolation of efficacy and safety data from other ind
130 al burden of disease, other factors, such as extrapolation of environmental sampling to the entire ex
132 rs and exhibits unique properties which make extrapolation of findings from the other two subtypes di
133 We use bottom-up (inventory, statistical extrapolation of flux measurements, process-based land a
135 entration of antibody was set at 10 IU/mL by extrapolation of functional assay correlates; however, t
136 ecasting of unprecedented events due to poor extrapolation of historical data to unsampled states.
137 s the study populations and end points used, extrapolation of indications, and the confirmatory natur
138 n squared error for MD forecasts with linear extrapolation of indices were 3.58 dB and 31.91 dB(2), a
141 onductivity of C60, obtained from the linear extrapolation of inverse conductivity vs. inverse length
143 rstand the functioning of the system and for extrapolation of laboratory findings of stressor impacts
144 fety regulations in structural design or the extrapolation of laboratory results to geophysical field
147 ere we use bottom-up (inventory, statistical extrapolation of local flux measurements, and process-ba
148 ent instead, a modification of the method by extrapolation of logarithmic selectivity coefficients ap
150 he stability is much lower than predicted by extrapolation of measurements made at high denaturant co
151 discussed seven independent approaches: (i) extrapolation of mobility to the zero power, (ii) initia
154 C- and O-glycosylation cautions against the extrapolation of models for S(N)1-type glycosylation wit
155 he activity distribution correctly penalizes extrapolation of models onto structurally different mole
156 The calculated effective dose, based on extrapolation of mouse data, was 0.0218 mSv/MBq, which w
157 action efficiency allowing for more accurate extrapolation of mutational levels in source samples.
158 uss the challenges specific to cross-species extrapolation of neutrophil function during mouse versus
159 inear prediction motion task that emphasized extrapolation of occluded accelerative object motion.
161 m the left ventricle, which precludes direct extrapolation of our knowledge of left-sided physiopatho
162 nterfacial free energy of 29(3) mN/m from an extrapolation of our results to the melting temperature.
164 e oxygen levels have largely been limited to extrapolation of paleoredox conditions reconstructed fro
170 dults and vaccine-induced immunity, or using extrapolation of protection from in-vitro immunoassay re
171 estimated to live 4.4 years on average from extrapolation of recent constant hazard rates beyond the
172 f biological organization and facilitate the extrapolation of results across routes of exposure, dosi
173 ntum observables) can be enhanced through an extrapolation of results from a collection of experiment
174 nd random variation among landscapes, making extrapolation of results from single scale, unreplicated
176 he mobile-phase density, complicating linear extrapolation of retention over longer or shorter column
177 subtypes, particularly in humans; this makes extrapolation of rodent findings to the human situation
178 c model parameters which would allow for the extrapolation of sensitivities to untested species.
179 , such hypotheses have largely relied on the extrapolation of single-cell responses to population res
180 obal mass balance estimates for GICs rely on extrapolation of sparse mass balance measurements repres
181 nferred from various tracers informed by the extrapolation of structures seen in other galaxies.
183 ublet levels is not consistent with a simple extrapolation of the calculated relative reaction cross
184 ced the understanding of its photochemistry, extrapolation of the conclusions to the real system requ
185 ncogene in the majority of melanomas, and in extrapolation of the correlation data, interference with
189 ension of supercooled water follows a smooth extrapolation of the IAPWS equation in the supercooled r
190 o be corrected for equilibrium, typically by extrapolation of the loss kinetics of performance refere
192 unrealistic synthetic solutions, which makes extrapolation of the obtained data to real-world applica
194 odiversity results not just from large-scale extrapolation of the process of adaptive radiation in a
197 ncrease was less than expected from a linear extrapolation of the trend observed at lower concentrati
198 in covalent inhibitor design, k(inact)/K(I), extrapolation of the underlying parameters, k(inact) and
199 e upwind terrain and the foundations for the extrapolation of the urban wind speed, measurements from
201 rees N and 40 degrees S, and the first-order extrapolation of these data suggests that the global low
202 cle oxidative phosphorylation cascade, while extrapolation of these data to the exercising muscle pre
205 among household contacts may also limit the extrapolation of these findings to the community setting
208 clinical use of this agent and has prompted extrapolation of these interpretive categories to other
209 s been demonstrated in bioassay experiments, extrapolation of these laboratory results to natural con
211 of connections, a principle that allows the extrapolation of this connectional feature to humans.
214 ialized properties, to the three-dimensional extrapolation of this technique to more complex structur
215 at higher tiers would ultimately require the extrapolation of toxicokinetics and toxicodynamics to un
216 e entity often prompts comparisons with, and extrapolation of treatment approaches from, primary auto
217 t research groups, leading to the paucity of extrapolations of experimental findings into understandi
218 se biases should temper the use of plots for extrapolations of forest dynamics to larger scales, and
223 ing to the obtained results and regardingthe extrapolations of the maximum residue limits existing fo
225 higher pressure phase boundaries are either extrapolations or inferred based on indirect evidence.
226 plants has not been shown previously and, by extrapolation, our findings suggest that cysteine-rich p
228 nd European emission inventories using three extrapolation proxies, namely the gross domestic product
229 o develop a quantitative in vitro to in vivo extrapolation (QIVIVE) approach for predicting in vivo a
230 ameters for quantitative in vitro-to-in vivo extrapolations (QIVIVE), but available prediction tools
232 of assessment and the challenges of species extrapolation require the development of alternative app
234 ent, and the fundamental assumptions for the extrapolation scheme are fulfilled for this specific cas
238 ropose a novel application of the simulation-extrapolation (SIMEX) procedure to address measurement e
241 62800 (32000-118000) averted infections, and extrapolation suggested that 202000 (98300-407000) infec
243 othesis, we trained subjects on a moving dot extrapolation task that makes distinct predictions for t
244 pts at solving this problem involve delicate extrapolations that are highly nonunique and that lack a
245 t for this effect, the (15)N(15)N data allow extrapolations that characterize mantle endmember delta(
247 e, and congenital fibrosis syndrome) and, by extrapolation, the hypoplasia or dysgenesis of noncephal
248 (SFTS) is one way to overcome the problem of extrapolation: the response at a given location in a war
249 he electrodes in a pi system is an immediate extrapolation; the theory then predicts that for some sp
250 he vicinity of the replication forks, and by extrapolation, this is also likely to be the case for th
251 energy of stable phases, without relying on extrapolation, thus enabling a formal assessment of wide
252 ions and on simplified models that allow for extrapolation to "infinitely" long polymers provide a so
259 curring within an environmental chamber, the extrapolation to atmospheric conditions can be assessed.
261 that salamanders aim their tongues by using extrapolation to estimate future prey position, thereby
263 rotoxicity within which these cells operate, extrapolation to human immune function has remained an o
267 r crater chronology and an updated dynamical extrapolation to Mercury, we find that the oldest surfac
268 impact local malaria dynamics is complex and extrapolation to other settings or future times is contr
270 resulting statistical models also allow for extrapolation to out-of-sample examples to provide a pre
272 This work is expected to provide a means of extrapolation to pre-clinical or human biodistribution w
273 re conducted under controlled conditions for extrapolation to real situations, we evaluate exposure r
277 xicity is preferably performed in vitro, but extrapolation to the in vivo outcome remains very challe
278 tration alters its speciation, rendering the extrapolation to the low dose exposure chemically incons
279 he nonthermostated capillary part, (v) inter/extrapolation to the nominal temperature, (vi) internal
280 he reliance on a rough figure of 400,000 for extrapolation to the total Yazidi population of Sinjar a
285 evidence of allometry, we made morphological extrapolations to infer body dimensions of *O. megalodon
287 ant plant trait distributions will not allow extrapolations to novel community assemblages in future
288 nt gradient profiles, by simple mathematical extrapolation using a known equation, thus offering very
289 D absent PCV7 introduction were estimated by extrapolation using either Poisson regression modeling o
293 as estimated using actual survival data with extrapolation using proportional hazard models adjusting
298 e was poor extrapolation between species and extrapolation was limited to geographic scales smaller t
299 mens for 1- and 2-d protocols based on those extrapolations will result in the expected radiation dos