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1 We first demonstrate the fundamental problem faced by a host: The presence of a genetically diverse m

2 10 years, and discusses the main challenges faced by a rapidly expanding system, in particular the c

3 ighlights challenges in early childhood care faced by academicians.

4 ic review aimed to understand the challenges faced by adolescents and young adults with these conditi

5 Challenges faced by adolescents fall into the realm of functional l

6 We have some understanding of the challenges faced by adolescents with asthma, less so for other alle

7 The navigational tasks faced by adults and juveniles differ fundamentally, beca

8 ants running on a trail, the main challenge faced by all collective systems is how to prevent traffi

9 is raising concerns about potential pitfalls faced by all EV researchers that will need to be address

10 ar energy, free ribosomes, and proteins, are faced by all living cells and we construct a mechanistic

11 The challenges faced by all stakeholders in building and developing cys

12 ce between anergy and activation, a decision faced by all T cells undergoing TCR stimulation.

13 A particular challenge faced by amine-based sorbents-the current leading techno

14 ship between the specific cognitive problems faced by an individual patient, their stage of disease a

15 diologic literature as they relate to issues faced by anesthesiologists.

16 owledge about this parasite and the problems faced by animal health agencies in controlling the disea

17 A universal challenge faced by animal species is the need to communicate effec

18 comotion is one of the major energetic costs faced by animals and various strategies have evolved to

19 EMENT Among the most basic survival problems faced by animals is balancing the need to seek food and

20 A central problem faced by animals traveling in groups is how navigational

21 tanding the complexity of the acoustic scene faced by animals vocalizing in groups.

22 The principal challenge faced by any color vision system is to contend with the

23 used to select these genes, the common task faced by any researcher is to translate these lists of g

24 llaborators, convened to identify challenges faced by Arab mental health researchers and propose an e

25 understanding and mitigation of health risks faced by astronauts.

26 affect their decisions in the moral dilemmas faced by autonomous vehicles.

27 tes understanding of psychosocial challenges faced by AYAs when diagnosed with and treated for cancer

28 Many of the challenges faced by AYAs with a diagnosis of malignant disease are

29 Hypoxia is a common challenge faced by bacteria during associations with hosts due in

30 iew will inform clinicians of the challenges faced by basic scientists and clinicians when treating b

31 In addition to the immediate consequences faced by biota living in roaded landscapes, road effects

32 Barriers faced by Black faculty and trainees included lack of rep

33 opportunities as well as new challenges are faced by both the surgeon and the anesthesiologist.

34 discuss the technical and social challenges faced by breeders using genome-editing tools for crop im

35 would encounter many of the same challenges faced by C(4) engineering programmes, the simpler leaf a

36 nergetic, biosynthetic and toxicity barriers faced by cancer cells.

37 initiatives to mitigate the financial burden faced by cancer survivors.

38 We will also discuss the challenges faced by candidate gene studies, such as differences in

39 approach to overcome some of the challenges faced by CAR-T cells; however, whether these engineered

40 e issues, is essential to address challenges faced by CE control programs.

41 covery to the present day, a major challenge faced by chemists has been the separation of RE elements

42 s among the most common psychiatric problems faced by children and adolescents, anxiety disorders hav

43 ot correspond to the most important barriers faced by children.

44 iders must be sensitive to multiple barriers faced by chronic sarcoid patients; acknowledging depress

45 luster, it can overcome many of the problems faced by classical clustering algorithms.

46 he obese to illustrate the common challenges faced by clinicians and discuss our approach.

47 highlighted the many challenges and dilemmas faced by clinicians assessing persons with disorders of

48 These failures reflect the difficulty faced by clinicians attempting to address multiple issue

49 tifying emerging pathways and the challenges faced by clinicians during clinical trials, the IDIBELL

50 aightforward, however, because of challenges faced by clinicians, health systems, and consumers.

51 This is the challenge faced by cognitive neuroscientists worldwide aiming to u

52 in, we describe some of the unique obstacles faced by contemporary trainee and practising surgeons en

53 vercome safety and antigen escape challenges faced by conventional chimeric antigen receptor (CAR) T-

54 mprinting to overcome some of the challenges faced by conventional protein imprinting.

55 o of the most prevalent and severe pressures faced by coral reefs.

56 le inhibitors represent important challenges faced by current anti-AXL therapeutics.

57 me the safety and energy density limitations faced by current lithium-ion technology.

58 rker, SDE1, addresses some of the challenges faced by current methods of nucleic acid-based assays an

59 erspective is offered, clarifying challenges faced by current non-optical platforms in developing pra

60 yloid aggregation, as well as the challenges faced by current probes and techniques, and the novel ap

61 We highlight the challenges faced by currently available technologies and provide pe

62 a comprehensive understanding of the issues faced by cyclists.

63 ity is an important and frequent fluctuation faced by D. vulgaris in its natural habitat.

64 veloped specifically to answer the questions faced by decision makers are called pragmatic or practic

65 However, significant challenges faced by developers as a product moves from the purely t

66 tional treatments suffers similar challenges faced by developers of conventional antibiotics; however

67 ved novel solutions to the common challenges faced by dividing eukaryotic cells.

68 The central problem faced by DNA binding proteins is how to select the corre

69 , the impact of eco-geographical constraints faced by domesticated plants and crop wild relatives on

70 tax deduction may be too low to defray costs faced by donors, lack of public awareness about the exis

71 owever, highlight the intrinsic complexities faced by drug developers pursuing histology-agnostic the

72 Alleviating the problems faced by dying persons and their families has drawn subs

73 ighlighting the different types of challenge faced by each country.

74 n to measure, by image shift, the deflection faced by each group of rays as they emerge from the obje

75 , pressures exerted by people who need care) faced by economies with high, middle, and low incomes, p

76 e discussed by analyzing the main challenges faced by electrochemical reduction of CO(2) .

77 nch to bedside." We also comment on the task faced by electrophysiologists and HF specialists as they

78 strategies for solving a biological problem faced by essentially all metazoans: how to generate two

79 However, the trade-offs faced by evolving bacterial populations presumably hinde

80 tant to identify the barriers and challenges faced by families as a result of genetic screening for S

81 on carbon, carbon markets reshape incentives faced by firms and reduce the value of emissions.

82 arge body of research documents the barriers faced by first-generation, low-income (FGLI) students as

83 ket-based response to a major policy problem faced by fisheries worldwide: the reallocation of catch

84 An important technical challenge faced by fluorescence microscopy-based measurement of ol

85 One of the challenges faced by global disease surveillance efforts is the lack

86 unities to address the increasing challenges faced by health care systems globally.

87 that is necessary to address the challenges faced by health systems in providing high-quality and co

88 ue to programmatic and structural challenges faced by healthcare systems in low-income countries.

89 is variation lies in a fundamental trade-off faced by helpers: by working harder, they increase the i

90 Key issues faced by hematologists in this era of new drugs include

91 Addressing the unique barriers faced by Hispanic men in engaging with the NDPP is criti

92 Overcoming barriers faced by homeless individuals in accessing TB treatment

93 sociated with challenges distinct from those faced by hospitals.

94 A fundamental problem faced by humans is learning to select motor actions base

95 isparities in patient choice and competition faced by individual centers emerged.

96 is critical to understanding the trade-offs faced by individual nodes in a network.

97 the identification of particular challenges faced by individuals after treatment for CRC.

98 ine and mitigate the particular health risks faced by individuals receiving sex steroid treatment.

99 ion providing free education on legal issues faced by individuals with cancer, between March 1, 2021,

100 his paper provides an overview of challenges faced by industry, regulators, and society in general in

101 lycemia is a common and serious complication faced by insulin-treated diabetic patients.

102 eveloped a taxonomy of the rationing choices faced by intensivists as a framework for ethical analysi

103 It reflects on many of the ethical tensions faced by internists and their patients and attempts to s

104 research, and discusses the ethical problems faced by investigators at each IDEAL stage.

105 ends, we summarize methodological challenges faced by investigators, and the tools, techniques and an

106 Despite numerous challenges faced by investigators, study staff, and participants, i

107 of human traits, highlighting the challenges faced by investigators--in particular, insufficient link

108 Challenges faced by laboratories include emerging pathogens, rapidl

109 n the web-is a fundamental computing problem faced by large-scale information retrieval systems.

110 rical paper, as understanding the challenges faced by lead writers will help co-authors to contribute

111 This situation is similar to that faced by Leeuwenhoek in the seventeenth century, whose w

112 The authentication issue was faced by Linear Discriminant Analysis (LDA) and Soft Ind

113 implemented to tackle the diverse challenges faced by local health-care systems.

114 hey add yet another hurdle to the challenges faced by low-status individuals.

115 ons that mimic the intracellular environment faced by M. tuberculosis.

116 fections (ARIs), we highlight the challenges faced by mAb-based immunotherapies for COVID-19.

117 nder widely varying environmental conditions faced by maize as it was migrated away from its domestic

118 children and adolescents is a vexing problem faced by many clinicians.

119 Surprisingly, the problems faced by many dyslexic children are by no means confined

120 databases is still one of the major problems faced by many life sciences laboratories.

121 cyclic peptide format overcomes a limitation faced by many peptide leads and appears to be suitable f

122 The extent of threats faced by marine systems, and their resilience to them, r

123 way, circumventing the difficulties that are faced by maximum likelihood methods.

124 transparent and reproducible AI research as faced by McKinney et al., and provide solutions to these

125 A critical evaluation of the problem space faced by medicinal chemists and cognitive models of cate

126 ubstrates is a ubiquitous selection pressure faced by microbes, yet intracellular trade-offs can prev

127 One of the limitations currently faced by microbial electrochemical cell (MXC) technologi

128 r experiments reveal a fundamental challenge faced by microbial strains that live in porous environme

129 his ability, likely a vicious cycle scenario faced by microglia in Parkinson's disease.

130 perature represent one of the major stresses faced by microorganisms as they affect the function of t

131 threats associated with anthropogenic change faced by migrating individuals may be shifting the relat

132 d fewer still have considered economic risks faced by millions of smallholders.

133 ns such as memory and executive function, is faced by most older adults and affects function and qual

134 ctionally and reflects the unique challenges faced by motors that move nucleosomes.

135 ing the adaptation and mitigation challenges faced by multiple sectors in California.

136 The task faced by MutM of locating rare oxoG residues embedded in

137 Society to understand the initial challenges faced by myeloma patients during the COVID-19 pandemic.

138 transmission changed the selection pressures faced by MYXV, altering the course and pace of virus evo

139 s over the Li counterpart and the challenges faced by Na metal anodes.

140 These findings redefine the challenges faced by nature in controlling the biosynthesis of compl

141 rpassed efficacy has intensified the dilemma faced by neurologists treating people with epilepsy, and

142 essential to overcome the reported barriers faced by nurses internationally.

143 s methodological challenges similar to those faced by nutritional epidemiology research.

144 s after therapy is one of the major problems faced by oncologists.

145 Many of the issues faced by Ontario are relevant beyond Canada, including i

146 gulation of cell shape is a common challenge faced by organisms across all biological kingdoms.

147 re specific predictions about the trade-offs faced by organisms in the allocation of bioenergetic and

148 ave functions that correlate with challenges faced by OSNs.

149 es unique challenges and issues beyond those faced by other age groups.

150 ology (ASM) in meeting the future challenges faced by our discipline.

151 natural selection to solve adaptive problems faced by our hunter-gatherer ancestors.

152 e tradeoff between consumption and longevity faced by parasites.

153 eview identifies and explores the challenges faced by parents and their (non)affected or at risk chil

154 ed under iron limitation, a common condition faced by pathogens inside the host.

155 This review will highlight the challenges faced by patients and couples and reveal the tremendous

156 social stigma and embarrassment that may be faced by patients.

157 vestments to address the specific challenges faced by people living in remote areas.

158 ng and mitigating the barriers to employment faced by people with CF.

159 for understanding communication difficulties faced by people with hearing loss.

160 (2.5) levels nearly one SD higher than those faced by people with the lightest skin tones.

161 These challenges faced by people with zoonotic tuberculosis might not be

162 A challenge faced by peptidases is the recognition of highly diverse

163 unting diagnostic and therapeutic challenges faced by periodontists.

164 i) deficiency is a major nutritional problem faced by plants in many agro-ecosystems.

165 driven by evolutionary convergent trade-offs faced by plants.

166 n cohort study was to define the cancer risk faced by PMS2 mutation carriers.

167 r maps highlight an additional vulnerability faced by poorer individuals in remote areas and can help

168 icitly define an ecological genetic obstacle faced by populations of an exotic species on its way to

169 o give an overview of some of the challenges faced by preclinical stroke research, and suggest potent

170 weak health systems, heightens the challenge faced by prescribers.

171 spite the barriers to kidney transplantation faced by presumed unauthorized immigrants and residents

172 operating conditions, overcoming limitations faced by previous healing agents such as chitosan agglom

173 ple allows the system to overcome challenges faced by previously reported reusable sensors, such as e

174 on Center (REC) program to ease the barriers faced by primary care physicians and rural and critical-

175 ed as an analog of natural foraging problems faced by primates.

176 recognition and management of ongoing issues faced by prostate cancer survivors may impact the overal

177 Inadequate data exist on the health problems faced by prostituted children, who are at high risk of i

178 g non-sequence-specific ligands is a problem faced by proteins in all organisms.

179 That is, much of the difficulty faced by providers after providing critical care service

180 VHD) poses one of the most vexing challenges faced by providers who care for patients after allogenei

181 ists discusses the most important challenges faced by RCTs in cardiac surgery and provides a list of

182 gued that the level of epistemic uncertainty faced by regulators has substantially decreased.

183 r small cell lung cancer, discuss challenges faced by regulatory agencies, and highlight paradoxical

184 The challenge faced by research into the genetic basis of complex dise

185 oing a PhD tend to focus on the difficulties faced by research students.

186 The major challenge faced by researchers attempting to complete mutation ana

187 t an introductory overview of the challenges faced by researchers in developing valid and reliable bi

188 Here we reflect on analogous challenges faced by researchers in infectious diseases.

189 o helps in solving the long-standing problem faced by researchers investigating experimental mouse br

190 However, a critical challenge faced by researchers is how to optimize the choices of s

191 amine the approaches used and the challenges faced by reviewers when nonrandomized studies are includ

192 ectives that focus on the special challenges faced by scientists in discovering potential new chemica

193 the entire human genome, a major difficulty faced by scientists in planning costly population-based

194 our algorithm overcomes the intrinsic issues faced by sequence similarity-based methods, when ortholo

195 Common challenges faced by sites included that clinical autopsies were nei

196 ular in their design and overcome challenges faced by small-molecule organic materials for battery ap

197 n of disease and the increased risk of death faced by smokers.

198 nce hypothesis, understanding the challenges faced by social animals is key to understanding the evol

199 mellitus and coronary heart disease already faced by South Asian countries, recent studies suggest t

200 alistic turbulent environments-a common task faced by species that rely on olfactory cues for navigat

201 lternatives, given some of the disadvantages faced by spectrophotometric methods such as the use of e

202 One challenge faced by stem cell biologists is the bioengineering of a

203 The logistical difficulties faced by steroid receptors or other transcription factor

204 We prove that the optimization problem faced by such an individual is NP-complete, meaning that

205 have been achieved in cancer control, issues faced by survivors have become increasingly relevant.

206 at somatic distress is the biggest challenge faced by survivors long after HCT.

207 been made in recognizing many of the issues faced by survivors, gaps in comprehensive surveillance a

208 A critical challenge faced by sustainability science is to develop strategies

209 t - can help us to understand the challenges faced by synthetic biology researchers.

210 A dilemma faced by teachers, and increasingly by designers of educ

211 to overcome some major fundamental obstacles faced by the ASSB community, as well as potential strate

212 A fundamental problem faced by the auditory system of humans and other vertebr

213 t important and poorly understood challenges faced by the auditory system.

214 rrent major technical and economic challenge faced by the biofuels industry.

215 ir of neural trajectories, and the challenge faced by the brain is how to select and match preexistin

216 nto perceptual decisions is a core challenge faced by the brain.

217 ls to mimic the real-time estimation problem faced by the brain.

218 , structure, accomplishments, and challenges faced by the Canadian National Transplant Research Progr

219 he whey fluid is one of the major challenges faced by the cheese manufacturing industry.

220 t current particle size metrology challenges faced by the chemical industry due to these emerging num

221 utations presents one of the main challenges faced by the clinical genetics community today.

222 t will highlight contemporary AST challenges faced by the clinical laboratory, and propose some solut

223 The challenges faced by the cooperative groups to the incorporation of

224 sfactorily tackle great challenging problems faced by the density functional theory recently discusse

225 One of the major challenges faced by the developing visual system is how to stably p

226 rief analyses were presented of the problems faced by the European neuroscience community in its atte

227 Additionally, we discuss the challenges faced by the existing classes of alpha3beta4 nAChR ligan

228 lect on the key challenges and opportunities faced by the field of genetics and genomics.

229 onsider the future directions and challenges faced by the field of metabolic network flux phenotyping

230 Finally, we discuss the new challenges faced by the field of natural products and the future of

231 the ability to resolve key ethical problems faced by the field of psychiatry.

232 m highlights the data-aggregation challenges faced by the field, suggests potential collaborative sol

233 in kidney donors has been compared with risk faced by the general population, but the general populat

234 primary environmental and social challenges faced by the global community.

235 to be one of the most ubiquitous conditions faced by the healthcare team, and has a significant emot

236 The challenges faced by the Israeli health-care system include a growin

237 nds in sufficient time to limit the pressure faced by the National Health Service (NHS) and maintain

238 ng time is one of the fundamental challenges faced by the nervous system in mediating behavior.

239 th its elegant formalization of the problems faced by the nervous system, it promises to become a maj

240 ncy sensory information is a crucial problem faced by the nervous system.

241 One of the main challenges faced by the nuclear industry is the long-term confineme

242 pments in three areas of pediatrics commonly faced by the office practitioner.

243 gation in three areas of pediatrics commonly faced by the office practitioner.

244 tanding economic and environmental challenge faced by the oil and gas industries.

245 ion delays simplifies computational problems faced by the optic tectum.

246 irations of its leadership and the realities faced by the organisation on the ground.

247 A significant difficulty faced by the pharmaceutical industry is the initial iden

248 Some of the higher risk variables faced by the practitioner are identified for submission

249 Because many problems faced by the primate brain in the control of movement ha

250 are consistent with the multiple challenges faced by the program in these regions as a result of con

251 drug repositioning), discuss the challenges faced by the repurposing community and recommend innovat

252 We also discuss the challenges faced by the resource given the explosive growth in sequ

253 ing such a fact, one of the major challenges faced by the scientific community is to find ways to pre

254 One of the many harmful factors faced by the skin is solar UV radiation, which damages s

255 ny nutritional stresses and other challenges faced by the spirochete in ticks and animal reservoirs.

256 ct recognition which belies the difficulties faced by the system when learning in natural visual envi

257 A major hurdle faced by the two leading LAVs is uneven replication of v

258 Such challenges are faced by the US/Europe, but are particularly acute in de

259 nat-IG under various conditions likely to be faced by the user, and show that its network-based appro

260 than the ecological constraints to invasion faced by the virus population.

261 A basic task faced by the visual system of many organisms is to accur

262 ed the distinct eco-geographical constraints faced by their host plants.

263 ce twice the risk of mortality and morbidity faced by their younger peers.

264 One of the major challenges faced by therapeutic polypeptides remains their invasive

265 of human disease and evaluate the challenges faced by these approaches.

266 icular concern is the food safety challenges faced by these individuals and the high risk of suscepti

267 nt role to play in mitigating the challenges faced by these individuals.

268 for understanding the evolutionary pressures faced by these lineages.

269 A significant hurdle faced by these methods, however, is the complexity inher

270 crease awareness of the adherence challenges faced by these patients, we have reviewed the published

271 2) RR, NRR, and OER), the current challenges faced by these reactions, and the recent efforts to meet

272 , giving a sense of the "design" constraints faced by these receptors.

273 discuss technical and scientific challenges faced by these systems before they are widely adopted by

274 A fundamental challenge faced by these systems is that reliance on protein-ligan

275 The principal challenge faced by these technologies is the need for high-through

276 ndations, which has exacerbated the problems faced by these trainees.

277 We also highlight the challenges faced by this field by the potential damage caused by co

278 Contributing factors to the challenges faced by this group include distinctive disease biology,

279 ral history and of other lifestyle decisions faced by this model organism.

280 tional process that overcomes entry barriers faced by this multicapsid nonenveloped virus.IMPORTANCE

281 One of the major challenges faced by this rapidly growing field lies in data analysi

282 Challenges faced by this young technology will be discussed, includ

283 It considers some of the problems faced by those who try to interpret the taxonomy and sys

284 ental and chemotherapeutic stresses commonly faced by TNBC cells throughout the metastatic cascade.

285 ronmental sustainability are pressing issues faced by today's global population.

286 e-based strategies can overcome the barriers faced by traditional antimicrobials, including antibioti

287 technique overcomes one important limitation faced by traditional GC and even comprehensive 2D gas ch

288 meaningful way will be one of the challenges faced by transplant clinicians in the future.

289 ow to reflect new challenges and imperatives faced by trauma surgeons.

290 Biology, chemistry and medicine are faced by tremendous challenges caused by an overwhelming

291 poptotic resistance and to model a challenge faced by tumor cells during metastatic dissemination, we

292 rdose deaths in the United States, the risks faced by U.S. health care workers, who often have access

293 of this study is to document the challenges faced by uninsured, poor Mexican families when attemptin

294 ed States, attention has turned to pressures faced by universities and biomedical research institutio

295 heat exposure is becoming an important issue faced by urban built environments.

296 The advantages and challenges faced by users of the Bayesian approach are also discuss

297 ong different IDU cohorts and the challenges faced by vaccines in protecting against this mode of inf

298 The challenges faced by vaccinologists to create the next generation of

299 evention is reviewed in the context of risks faced by women with resected breast cancer.

300 ecades, much has been written about barriers faced by young people in accessing health care.