ライフサイエンスコーパス: facilitatory

1 bitory, its role in acute mechanical pain is facilitatory.

2 ffects of neighboring whiskers should be net facilitatory.

3 ic pain and cerebral ischemia, inhibition of facilitatory A(2A) receptors has profound neuroprotectiv

4 g through inhibitory A1 receptors (A1Rs) and facilitatory A2ARs, which have similar affinities for ad

5 uits modulate nociceptive transmission via a facilitatory action at spinal 5-HT(3) receptors.

6 ivated Icat which demonstrates an additional facilitatory action of [Ca2+]o.

7 that includes physiological features of the facilitatory action of dopamine on fast-spiking interneu

8 This is the first description of a facilitatory action of GABAB receptors and indicates tha

9 some glutamatergic fibers prevails over the facilitatory action of weakly, tonically activated nAChR

10 As part of their facilitatory action, retro-cues diminish the costs of re

11 Thus, serotonin receptor-evoked facilitatory actions are complex, and may involve altera

12 These two facilitatory actions of 5-HT are mediated by at least tw

13 The descending facilitatory actions of intra-PAG PGs play a direct and

14 d that repeated elicitation of noradrenergic facilitatory activity is one mechanism by which chronic

15 ld induce alterations in cortical inhibitory/facilitatory activity observed in TMS-evoked potentials

16 of splice site selection by antagonizing the facilitatory activity of MBNL1 and MBNL2 on IR exon 11 s

17 ffect (PPE) on M1 corticospinal activity was facilitatory after the initial target presentation and d

18 Steroids mediate both facilitatory and deleterious effects of stress on vestib

19 The half-maximal [Ca2+]o for the facilitatory and inhibitory action on Icat was 6 and 400

20 ug appears to switch the balance between the facilitatory and inhibitory actions of ACh.

21 is no framework to explain its wide range of facilitatory and inhibitory behavioral effects.

22 al extent of their receptive field with both facilitatory and inhibitory contributions.

23 erotonergic (5HT) neurons contribute to both facilitatory and inhibitory controls of spinal cord "pai

24 ce of nonserotonergic neurons, including the facilitatory and inhibitory controls that originate from

25 evidence of an increased sensitivity to the facilitatory and inhibitory effects of previous processi

26 613 resulted in almost equal distribution of facilitatory and inhibitory effects.

27 ar sensitivity to InsP3, which provides both facilitatory and inhibitory feedback on Ca2+ signalling.

28 Facilitatory and inhibitory functional interactions betw

29 show that a relative shift in the balance of facilitatory and inhibitory functions results in differe

30 t D(1) and D(3) receptors exert a respective facilitatory and inhibitory influence on extracellular l

31 the spinal cord is regulated by a balance of facilitatory and inhibitory influences operating on the

32 Moreover, there were both facilitatory and inhibitory influences, just as there ar

33 d to investigate and compare the activity of facilitatory and inhibitory intracortical circuits in a

34 iated synaptic exocytosis is orchestrated by facilitatory and inhibitory mechanisms.

35 nociceptive transmission receives descending facilitatory and inhibitory modulation from supraspinal

36 Our study highlights the facilitatory and inhibitory modulations that occur durin

37 atergic transmission and the balance between facilitatory and inhibitory pathways.

38 concurrent activation of central descending facilitatory and inhibitory systems.

39 d aIPL-M1 cortico-cortical interactions were facilitatory and inhibitory, respectively, in healthy vo

40 Specifically, we observed facilitatory and interference effects when targets were

41 on subjective brightness that includes both facilitatory and suppressive effects, and these interact

42 btypes (5-HT7 and 5-HT2a) that have opposing facilitatory and suppressive influences, respectively, o

43 phasize the dynamics and the complexities of facilitatory and suppressive interactions between the re

44 There were both facilitatory and suppressive interactions that differed

45 rences in the preferred orientations between facilitatory and suppressive profiles were relatively la

46 rception, possibly due to the combination of facilitatory and synesthetic effects of general relevanc

47 the central auditory system, excitatory (or facilitatory) and inhibitory neural interactions take pl

48 Here we demonstrate that facilitatory anodal transcranial direct current stimulat

49 roles of p75 (i.e., TrkA independent or TrkA facilitatory) are responsible for NGF-mediated protectio

50 tory receptors, and synaptic activation of a facilitatory autoreceptor has not been established.

51 The presynaptic facilitatory autoreceptor, which modulates glutamate rel

52 Facilitatory binocular neurons and mildly suppressive bi

53 nistration regimen, CRF1 activation remained facilitatory, but CRF2 activation facilitated rather tha

54 ional unit of callosal influence comprises a facilitatory centre and a depressing peripheral zone, wh

55 TMS) has been used to examine inhibitory and facilitatory circuits during experimental pain and in ch

56 eflecting the contribution of inhibitory and facilitatory circuits in M1.

57 nor GABA neurotransmission are required for facilitatory combination-sensitive interactions in IC.

58 s), glycine (GlyRs), and GABA (GABA(A)Rs) in facilitatory combination-sensitive interactions.

59 The findings provide strong evidence that facilitatory combination-sensitive response properties p

60 Besides this across-network reorganization, facilitatory connectivity between regions of the languag

61 s are associated with an enhanced descending facilitatory control of mechanical responses of spinal n

62 l loops leading to descending inhibitory and facilitatory controls of spinal neuronal activity that f

63 However, some facilitatory cortical neurons fire for only one eye, but

64 ucleus is critical to balance inhibitory and facilitatory cortical players within the motor program.

65 red tIDS with the most efficient noninvasive facilitatory corticospinal tES known so far, which is 20

66 gical impairment (i.e., less inhibitory/more facilitatory cPMd-iM1 measure at rest as assessed with p

67 dogenous, tonic-inhibitory D2-like and tonic-facilitatory CRF2 receptor actions.

68 stimuli in male rats, suggesting a mutually facilitatory cross-regulation between central pathways r

69 results lead to the conclusion that movement facilitatory decreases in internal pallidal (GPi) activi

70 d receptor-dependent increases in descending facilitatory drive from the brainstem rostral ventromedi

71 This effect was associated with a stronger facilitatory drive from the right pIFG to the left pIFG

72 necessary to recruit descending serotonergic facilitatory drive required to observe the inhibitory ef

73 is accompanied by an enhanced net descending facilitatory drive that contributes to an amplification

74 200 microg/kg i.v. dose of the neuromuscular facilitatory drug edrophonium.

75 suckling (bursting cells) or after injecting facilitatory drugs (non-bursting cells).

76 ts in their entirety, in particular, for the facilitatory effect at intermediate to high contrasts af

77 Control experiments prove that the facilitatory effect is not caused by integrating colour

78 unlesioned posterior parietal cortex and the facilitatory effect of anodal transcranial direct curren

79 The overall facilitatory effect of CICR on glutamate release induced

80 ndicate that ADX does not affect LHSS or the facilitatory effect of cocaine.

81 t D,L-2-amino-5-phosphovalerate (APV) on the facilitatory effect of context preexposure.

82 These results document a facilitatory effect of d-amphetamine on use-dependent pl

83 ress disorder in humans, consistent with the facilitatory effect of D-serine on fear extinction.

84 Conversely, the facilitatory effect of end zones in length-summing cells

85 Our results show for the first time that the facilitatory effect of endogenous H2S in the mouse SMG i

86 The facilitatory effect of external calcium ions (Ca2+o) on

87 The facilitatory effect of GON stimulation on dural stimulat

88 The facilitatory effect of Ins(1,4,5)P3 was also manifest as

89 een on reduction of [Ca2+]o and there was no facilitatory effect of Mgo2+.

90 f cation channels, which may account for the facilitatory effect of micromolar concentrations of Ca2+

91 d axial muscle response, consistent with the facilitatory effect of midbrain central gray infusions o

92 udy, we tested the hypothesis that the acute facilitatory effect of norepinephrine (NE) in mPFC becom

93 APV blocked the facilitatory effect of preexposure.

94 Our results revealed that the facilitatory effect of THC was inhibited by antagonists

95 ole for calmodulin-dependent systems in this facilitatory effect of the compound.

96 The facilitatory effect of UTP on P2X(2) sustained currents

97 e or blockade of CB1 receptors abolished the facilitatory effect of VU0360172.

98 n of the neurotrophin BDNF has an unexpected facilitatory effect on anxiety-like behavior, concomitan

99 Furthermore, a direct pathway from S1 has a facilitatory effect on auditory responses in higher-orde

100 Such dysregulation appears to have a facilitatory effect on cardiovascular disease developmen

101 eceptors in the striatum exerts a widespread facilitatory effect on cortical function.

102 , the lower doses of CRF (3 and 10 ng) had a facilitatory effect on LS unit activity, peaking at abou

103 revealed that positive social feedback had a facilitatory effect on motor coordination in the control

104 suggest that systolic cardiac signals have a facilitatory effect on motor excitability-in contrast to

105 tion in humans with SCI, resulting in lesser facilitatory effect on motor neurons.

106 In rodents, this facilitatory effect requires previous exposure to estrad

107 of muscle afferents had a significant longer facilitatory effect than cutaneous stimulation (P < 0.05

108 This facilitatory effect was not observed in the presence of

109 This facilitatory effect was not present in schizophrenia pat

110 a fast-acting, direct G-protein action, the facilitatory effect was slower and was blocked by inhibi

111 perpolarizing BK channel current exceeds its facilitatory effect, causing truncation of transmitter r

112 To understand the origin of this facilitatory effect, we examined short-interval intracro

113 er 5-HT can have an exclusively postsynaptic facilitatory effect.

114 The facilitatory effectiveness of spindle afferent feedback

115 tory mechanisms or a reduction in descending facilitatory effects after DLFX that alter Fos protein e

116 roinflammatory cytokines exert powerful pain facilitatory effects following their release in the body

117 The facilitatory effects induced by oxo-M on BAN activity we

118 inals of presumed interneurons suggests that facilitatory effects may involve a mechanism of disinhib

119 treated with capsaicin (125 mg/kg, s.c.) the facilitatory effects of 50 muM oxo-M on BAN activity wer

120 Oxytocin blocked the facilitatory effects of acute alcohol on GABA release in

121 Thus, the NO-cGMP pathway mediates the facilitatory effects of alpha(1)-adrenoceptors on lordos

122 thin the RF but had a large influence on the facilitatory effects of contextual lines.

123 ported role of D3 receptors in mediating the facilitatory effects of cues in addiction.

124 The facilitatory effects of external Ca2+, Sr2+ and Ba2+ (Ca

125 the potential role of eCBs in mediating the facilitatory effects of fluoxetine on fear extinction ha

126 plasticity." In this report, we describe the facilitatory effects of high-frequency stimulation on th

127 completely clear, evidence suggests that the facilitatory effects of leptin on breathing require the

128 lac (10 microM) significantly attenuated the facilitatory effects of LPS and IL-1b, indicating involv

129 doses of AP-7 into the PAG also blocked the facilitatory effects of medial hypothalamic stimulation

130 0 nmol/0.25 microliter) delivery blocked the facilitatory effects of pentagastrin.

131 cleus, but also could provide a "memory" for facilitatory effects of repeated neural activity, seen i

132 in humans to determine where suppressive and facilitatory effects of spatial attention are expressed.

133 The facilitatory effects of the high-frequency stimulation-i

134 Paradoxically, DAMGO produced facilitatory effects on mEPSCs, which were mediated by p

135 Besides the facilitatory effects on the ryanodine-sensitive channels

136 Facilitatory effects persisted for at least 30 min.

137 This review focuses on the powerful pain facilitatory effects produced by the immune system.

138 ll active intensities resulted in equivalent facilitatory effects relative to sham while for cathodal

139 ditioning induced more frequent and powerful facilitatory effects than cPMv.

140 interactive effect was inhibition, although facilitatory effects were seen as well (2 of 13).

141 These facilitatory effects were then blocked by pretreatment w

142 iol:BSA implants to the MBH and POA produced facilitatory effects.

143 ility, which are thought to underlie several facilitatory forms of learning in Aplysia, appear to hav

144 by descending controls, both inhibitory and facilitatory, from the midbrain and brainstem.

145 By contrast, acute stress may have a facilitatory impact on spatial representations.

146 has been shown to have a permissive, if not facilitatory, impact on smooth muscle cell proliferation

147 ch is inhibitory in sign in subordinates and facilitatory in dominants.

148 t this influence became less inhibitory/more facilitatory in patients with greater clinical impairmen

149 al impairment was associated with a stronger facilitatory influence of cPMd TMS on blood oxygenation

150 y of human semantic processing is the rapid, facilitatory influence of prior input on extracting the

151 periments showing that nitric oxide exerts a facilitatory influence on pacemaking currents in the sin

152 e instances of imagery can have a pronounced facilitatory influence on subsequent conscious perceptio

153 ntidiuresis and antinatriuresis by its known facilitatory influence on the actions of an increase in

154 c hypoxia; adenosine may exert a presynaptic facilitatory influence on the vasoconstrictor responses

155 cus coeruleus was previously shown to have a facilitatory influence on thermal nocioception according

156 lection of objects, perhaps by spreading its facilitatory influence throughout the boundaries of an o

157 ionally, patients with frontal stroke showed facilitatory influences from the right lesion homologue

158 gracilis (NG) and is dependent on descending facilitatory influences from the rostral ventromedial me

159 valled ability to measure the inhibitory and facilitatory influences of PMd over the primary motor co

160 al cortex generates top-down center-surround facilitatory-inhibitory effects on geniculocortical tran

161 the brainstem midline region as a source of facilitatory input for the vomiting process.

162 at the lesions remove an important source of facilitatory input to spinal respiratory motoneurons and

163 , at least for the first MEP peak, is due to facilitatory interaction between I waves, and takes plac

164 d local (i.e., dHPC) estrogen synthesis, the facilitatory interaction effect appeared independent of

165 BF of the neuron, is superimposed onto this facilitatory interaction, presumably mediating responses

166 ion-sensitive neurons display time-sensitive facilitatory interactions between inputs tuned to distin

167 an be explained by two factors: One is local facilitatory interactions between the orientation select

168 neurons, with or without GABA(A)R blockade), facilitatory interactions were eliminated.

169 Facilitatory interactions were found in 46 of 264 (17%)

170 and the contributions of suppressive and/or facilitatory interactions, varied considerably from one

171 een the right and left eyes, and some showed facilitatory interactions.

172 e internal solution results in a loss of the facilitatory mechanism.

173 Here, we present the first evidence for facilitatory mechanisms of FM sweep selectivity.

174 eptive potency by activating descending pain facilitatory mechanisms to exacerbate spinal nociceptive

175 neurons may contribute to the heterosynaptic facilitatory mechanisms underlying mechanical hyperalges

176 pecific spinal circuitry, via heterosynaptic facilitatory mechanisms, to mediate mechanical hypersens

177 gnificance of endogenous pain inhibitory and facilitatory mechanisms.

178 This positive outcome was associated with a facilitatory metabolic response including higher abundan

179 c phase, patients with frontal stroke showed facilitatory modulation from the right dorsolateral pref

180 Exogenous zinc also inhibits the facilitatory modulation of mossy fiber axon excitability

181 ferent processing in the spinal cord and (2) facilitatory modulation of the descending limb of the mi

182 Additionally, facilitatory modulations were found at an ISI of 60 ms,

183 incomplete summation seem unnecessary for V1 facilitatory neurons or contrast sensitivity.

184 ls that are consistent with the existence of facilitatory nicotinic ACh receptors on the motor nerve

185 lary raphe magnus (RM): opioids silence pain-facilitatory ON cells and produce sustained discharge in

186 During feeding, pain-facilitatory ON cells were inhibited and pain-inhibitory

187 tic vesicle fusion, and the strength of each facilitatory or inhibitory function differs significantl

188 atically with food intake and are subject to facilitatory or inhibitory influences within the central

189 ignal delays in the DS circuit and the sign (facilitatory or suppressive) of DS interactions.

190 ime delay and whether the DS interaction was facilitatory or suppressive.

191 d combination-sensitive because they display facilitatory (or inhibitory) responses to the combinatio

192 i) Gain control based on overall excitatory, facilitatory, or inhibitory corticofugal modulation.

193 The model incorporates excitatory and facilitatory pathways activated by the positive value of

194 evidence implicates serotonergic descending facilitatory pathways from the brainstem to the spinal c

195 suggests that the threshold of intracortical facilitatory pathways is decreased in PD.

196 Such activation of descending facilitatory pathways might be the result of neuroplasti

197 macological block of descending serotonergic facilitatory pathways.

198 s mainly due to a narrowing of the extent of facilitatory perceptual spatial interactions.

199 Thus, absent facilitatory plasticity in smokers during nicotine withd

200 In smokers during nicotine withdrawal, facilitatory plasticity induced by tDCS and PAS was abol

201 l be interesting to determine how widespread facilitatory presynaptic KARs are at other synapses in t

202 functional relationship between an intrinsic facilitatory process (PTP) and extrinsic inhibitory modu

203 Abnormal activity of facilitatory processes may thus represent a mechanism of

204 ps that could alter the tuning properties of facilitatory profiles.

205 otif, suggesting that these interactions are facilitatory rather than essential.

206 ding maximizing at about 5 min followed by a facilitatory rebound, especially at the 100 ng dose, max

207 In contrast, very little is known about facilitatory receptors, and synaptic activation of a fac

208 e TIP39 ligand/PTH2 receptor system provides facilitatory regulation of the hypothalamic-pituitary-ad

209 ic potentiation (PTP) or edrophonium-induced facilitatory response involves the occurrence of a stimu

210 Adaptive facilitatory responses are often preceded by acquired tr

211 The pharmacology of the inhibitory and facilitatory responses differed.

212 Facilitatory responses to 36 single IC neurons were reco

213 NK1 receptors in SP-induced vomiting, and a facilitatory role for gastrointestinal NK1 receptors.

214 Preclinical studies suggest a facilitatory role for inflammatory markers in aggression

215 ies suggest that central vasopressin plays a facilitatory role in aggressive behavior.

216 have pointed to either an inhibitory and/or facilitatory role in exocytosis, and the role of Cplxs i

217 f PcrA, although not essential, might play a facilitatory role in the RecA displacement reaction.

218 at central 5-HT7 receptors play an important facilitatory role in the reflex activation of vagal outf

219 ggest that this modification pattern plays a facilitatory role in the transcription process in a mann

220 play an inhibitory role, while others play a facilitatory role modulating aggression.

221 first direct demonstration of a predominant facilitatory role of extrastriatal A(2A)Rs.

222 Our study provides causal evidence for the facilitatory role of pre-sleep behaviors in sleep initia

223 at an intact synapse, again indicative of a facilitatory role.

224 nhibitory effect is competed by a downstream facilitatory sequence (amino acids 405-454).

225 esults suggest that activation of descending facilitatory serotonergic influences by a prolonged noxi

226 adrenoceptors, although serotonin, acting on facilitatory spinal 5-HT3 receptors, influences the fina

227 Anodal (facilitatory) stimulation to the ipsilesional hemisphere

228 n infants were mild; the overall strength of facilitatory subfield responses was lower than that in a

229 s had the subfield map where the neighboring facilitatory subfields substantially differed in their p

230 gree of homogeneity in the spatial matrix of facilitatory subfields.

231 ability of both corticospinal output and its facilitatory synaptic inputs from cortical and sub-corti

232 onal sensitization of a previously-deficient facilitatory system may be one mechanism whereby exposur

233 ly by a central, centrifugal descending pain facilitatory system which involves neurotensin in the RV

234 opioid-induced activation of descending pain facilitatory systems and enhanced expression and pronoci

235 a potential role for central descending pain facilitatory systems in mediating secondary hyperalgesia

236 suppression of activity in supraspinal motor facilitatory systems.

237 response curve on plasticity induced by both facilitatory tDCS and PAS.

238 solateral prefrontal cortex (DLPFC), anodal, facilitatory tDCS has been shown to improve symptoms in

239 For facilitatory tDCS, bromocriptine prevented plasticity in

240 We show that offset responses are more facilitatory than sound responses, even in neurons where

241 interactions between electrodes were either facilitatory (the perceived brightness produced by stimu

242 sometimes fatal to the tumor cells but also facilitatory to their survival and growth.

243 In addition, we show that this facilitatory top-down effect is sensitive to stimulus ex

244 uron simultaneously receives inputs from the facilitatory transmitter 5-HT at one set of synapses and

245 by multiple spaced pulses of the endogenous facilitatory transmitter serotonin (5-HT) [7, 8], could

246 tion induced at sensorimotor synapses by the facilitatory transmitter serotonin (5-HT).

247 We found that the facilitatory transmitter, serotonin (5-HT), enhanced the

248 y the neuroendocrine brain to coordinate the facilitatory transsynaptic and astroglial input to LHRH

249 Unexpectedly, this rule also applies to facilitatory true binocular neurons; although driven by

250 decreasing the relative contribution of the facilitatory versus inhibitory influences of ACh.

251 restricted range of conditions, and not in a facilitatory way.

252 r high concentrations reached gradually, are facilitatory, whereas high concentrations reached rapidl