ライフサイエンスコーパス: fact

1 RIXC and with the histone chaperone complex FACT.

2 s to reconcile these seemingly contradictory facts.

3 making decisions that seem contrary to those facts.

4 In fact, 17 % of his more than 600 publications appeared af

5 ontrol system and energy expenditure, are in fact a normalization to a lower body weight and not driv

6 In fact, a large proportion of islet-infiltrating B lymphoc

7 A remarkable fact about sea-level extremes is the existence of spatia

8 H2Bub is required for FACT activity in genic regions.

9 t one function of this histone chaperone, as FACT also functions in DNA replication.

10 In fact, although free rPrP(90-231) phase separated into la

11 In fact, although it is possible that dietary intake of SFA

12 We show that FACT and H2Bub globally repress antisense transcripts ne

13 More remote memory for both facts and autobiographical events was intact.

14 The hippocampus supports memory for facts and events, collectively known as declarative memo

15 lts could help reassure all communicators of facts and science that they can be more open and transpa

16 ot always) consider whether assertions match facts and source information stored in memory.

17 ding the frequent disconnect between knowing facts and, yet, making decisions that seem contrary to t

18 The large DNA-binding surface on FACT appears to be protected by the carboxy-terminal dom

19 therefore unclear what the core functions of FACT are, whether they differ in different circumstances

20 In fact, Argentinean vinegars have not been studied.

21 Thus, we propose a novel role for FACT as a factor preventing helicase dissociation from c

22 aperone facilitates chromatin transcription (FACT) as an interactor of substrate-bound Cas9.

23 In fact, assuming independence among a local population of

24 This suggests that unilateral PFV may in fact be a bilateral, asymmetric process, but the clinica

25 This may in fact be the first evidence for a change in the trend for

26 ant immunity and the plant microbiome is, in fact, bidirectional and that plants, microbiota, and the

27 sical assays indicate these compounds did in fact bind uPAR, and elicit cellular responses that affec

28 ditional end points were collected: HRQOL by FACT-BMT score at baseline and at days 7, 14, 28, 60, an

29 the restrictive-strategy group had a higher FACT-BMT score at day 100 (difference of 1.6 points; 95%

30 -related quality of life (HRQOL) measured by FACT-BMT score at day 100.

31 adjusting for transfusion type and baseline FACT-BMT score, the restrictive-strategy group had a hig

32 nt of Cancer Therapy-Bone Marrow Transplant (FACT-BMT) score relative to baseline.

33 rroborated by other techniques show that, in fact, carbamazepine is not a DNA intercalator.

34 However, the mechanism by which FACT causes these opposing outcomes is unknown.

35 In fact, changes in breed distribution reflect a shift towa

36 with the political bias detector Media Bias/Fact Check we quantify the relative reporting styles for

37 analyzing 125 recent rumors from six popular fact-checking sites, and their associated 289,202 tweets

38 nserved facilitates chromatin transcription (FACT) chromatin-reorganizing complex are required for bo

39 at such category-selective neurons do not in fact code individual categories in isolation but are als

40 NA) field: an increasing number of ncRNAs in fact codify for short peptides that have biological acti

41 The FACT-Cog included the 20-item Perceived Cognitive Impair

42 ssment of Cancer Therapy-Cognitive Function (FACT-Cog) questionnaire, administered at baseline, 3, 6,

43 in an irradiated patient population, and in fact compares favorably with regard to breast contractur

44 In fact, comparing the transcriptomes of transgenic LNJ ove

45 easures of robustness and performance are in fact competitive features that cannot be simultaneously

46 amined histone chaperones and found that the FACT complex recognized ADP-ribosylated histones and med

47 In fact, confocal microscopy reveals separated S:L-rich and

48 However, whether it is in fact contained within EVs or is instead an extravesicula

49 In fact, controversies persist regarding mechanisms that de

50 In fact, cortical superficial siderosis is emerging as a st

51 ACF using a moderate-accuracy test could in fact cost more overall than using a high-accuracy test.

52 In fact, current examples of direct, enantioselective inter

53 In fact, currently available PXR ligands are not highly sel

54 At baseline, no differences in the mean FACT-Cx total score were identified between the open sur

55 nd 6 weeks and 3 and 6 months after surgery (FACT-Cx was also completed at additional timepoints up t

56 ional Assessment of Cancer Therapy-Cervical [FACT-Cx], EuroQoL-5D [EQ-5D], and MD Anderson Symptom In

57 reveal that the voids in the collagen are in fact cylindrical pores with diameters of ~2 nm, while el

58 ir reanalysis, and the issues raised were in fact dealt with through the peer-review process.

59 ogenomic mosaics, and their diversity may in fact depend on the gene flow that shapes the oak genome.

60 asal level of replication stress defines the FACT dependence of cells.

61 In human cells, FACT depletion extends dCas9 residence times, delays gen

62 rm cells by recruiting the histone chaperone FACT, displacing histones, and initiating protective gen

63 In fact, downregulation of CAV1 expression resulted in the

64 In fact, drug delivery to brain remained a challenge in the

65 In fact, during the reduction of substrates, NQO2 generates

66 In fact, electrospinning and electrospraying methods are pr

67 rent cancer fusions both fusion partners, in fact, encode ZNRF3 regulators.

68 ring learning, multisensory processes can in fact enhance subsequent recognition memory for unisensor

69 urther, we show that this optimization is in fact equivalent to Lagrange multiplier optimization for

70 r in different circumstances, and what makes FACT essential in some situations but not others.

71 In fact, ET-plus might only represent a state condition (ie

72 In fact, evidence has now shown that the stroma is multi-fa

73 In fact, evidence suggests that early PD intervention has t

74 s, the mechanism for lattice expansion is in fact fully consistent with heat-induced thermal expansio

75 ne nanodomains has become widely accepted as fact, fundamental functional aspects, the roles of indiv

76 Responders' W15 total FACT-G score had improved (P = .025) compared with nonre

77 leased by interaction with H2A-H2B, allowing FACT-H2A-H2B to dock onto a complex containing DNA and h

78 In fact, higher activation in the CA1 and DG was associated

79 re distant nucleosomes is dependent upon the FACT histone chaperone, and FACT is recruited to these r

80 In fact, IL-38 (aa3-152, 1 ng/mL) is more potent than IL-37

81 The role of FACT in transcription would then be just one facet of a

82 pendent of the ADARs and ERI-6/7, and are in fact increased in adar- and eri-6/7-defective mutants be

83 ignificantly over the past decade and are in fact increasing at some sites, attributed to the prevale

84 These two experimental facts indicate that m-C(2)B(10)H(12) is thermodynamicall

85 ia accounts depict panic and cruelty, but in fact individuals often cooperate with and care for one a

86 We find that FACT is engaged in extensive interactions with nucleosom

87 tic and chemical tools, we demonstrated that FACT is needed to overcome replication stress.

88 thout serotonin release by maternal neurons, FACT is not recruited by HSF1 in germ cells, transcripti

89 pendent upon the FACT histone chaperone, and FACT is recruited to these regions when eviction is begi

90 The histone chaperone FACT is upregulated during mammary tumorigenesis and nec

91 This, in fact, is a puzzle because a molecular switching mechanis

92 is work, we demonstrate that the product, in fact, is formed via the connection of two unexpected cat

93 Radioresistance, in fact, is such a common feature in fungi that it is diffi

94 c to the specific application domain, and in fact it applies to simplified models of ecological, neur

95 FACT knockdown also increases epigenetic marking by dCas

96 t components of the instructions in the drug facts label for naloxone use and came close on two other

97 cal ingredients but have deceptive nutrition facts labels.

98 This calculated O-H BDFE of HP, in fact, lines up with an experimental demonstration of the

99 he acquisition of certain aneuploidies is in fact linked with a favorable prognosis.

100 data suggest a compelling mechanism for how FACT maintains chromatin integrity during polymerase pas

101 Furthermore, FACT maintains nucleosomes in subtelomeric regions, whic

102 hat promote limited cancer cell death may in fact make tumors more heterogeneous, increase aggressive

103 one or the other cytoskeletal system do, in fact, make use of both filament types.

104 nded best practices should involve using the facts (measurements) and the patterns they reveal to est

105 ns previously attributed to NF-kappaB are in fact mediated by these upstream kinases by novel mechani

106 In fact, molecular docking predicted a high affinity of CGA

107 In fact, neuronal subpopulations can also be estimated from

108 y region of a two-sender classical MAC is in fact NP-hard.

109 n between mental representations of the rote facts of a message-its verbatim representation-and its g

110 young children enrolled in Medicaid and, in fact, offers evidence that increased medical POHS was as

111 Knowledge gaps (number of errors on 7 facts on COVID-19 symptoms and prevention) and informati

112 We also bring new facts on the relationship between honey colloidal struct

113 In fact, one of our proposed variants of acquaintance immun

114 In fact, only 12% of GLUT1 resolved into a highly mobile su

115 ture of the smell and taste changes, and the fact our methodology does not take into account the poss

116 In fact, our analyses of early object processing in AlexNet

117 In fact, our method mimics two main strategies of morphogen

118 In fact, over the course of the last 20 years, the number o

119 least one post-baseline assessment of either FACT-P or EQ-5D-5L (PRO population).

120 In fact, pachytene piRNA loci are rapidly diverging even am

121 Carlo calculations, and it is shown how this fact paves the way for the formation of ultrastable wate

122 In fact, previous studies have shown that actin cross-linke

123 In fact, pro- and anti-inflammatory macrophages differ in t

124 d phenotypes, the effects of ageing might in fact prove a prerequisite to ALS, rendering the cells su

125 In fact, RBM14 binds to RNA:DNA hybrids.

126 ating a mantle origin for nitrogen(7-10), in fact represent dominantly air-derived N(2) that experien

127 DNB and ISS is not only instrumental, but in fact represents a real detection of light scattered by t

128 future of consilience, with a role both for fact-seekers, and searchers for understanding.

129 Moreover, in the absence of Pob3, the FACT Spt16 subunit controls the 3' end of genes.

130 a key role for the histone chaperone complex FACT (SPT16 and SSRP1) in governing Cas9 turnover at the

131 tations can be learned without awareness; in fact, strikingly, awareness seems to hinder the exploita

132 These facts suggest that RCC meets some of the criteria for sc

133 This fact suggests that RFs of SDs cannot be defined as homog

134 As a matter of fact, testing accelerates life-saving decisions on treat

135 rience with harassment at AADR meetings, the fact that 1 in 5 did should be cause for concern.

136 Concerns raised by the fact that 80% of the individuals had PCB levels above th

137 ng native structures, as demonstrated by the fact that 87.8% of the predicted structures shared a roo

138 oduction of such measures is hampered by the fact that a sizeable part of the population fails to see

139 of articular cartilage, as evidenced by the fact that aberrant FGF signalling contributes to the mal

140 ave ignored sensory uncertainty, despite the fact that accounting for the current level of perceptual

141 However, despite the fact that all pathogenic arenaviruses from South America

142 The fact that all these pleiotropic SNPs have opposite allel

143 This method capitalizes on the fact that although we remain largely unaware of our eye-

144 Our experiments also highlight the fact that assessments of thermal gradients by changes in

145 Our approach leverages the fact that at early stages, tumors recruit hematopoietic

146 The fact that bacteria can passively form coherent bundles,

147 d on studies of viral pathogens, despite the fact that bacterial pathogens may exhibit very different

148 em with TonB substrates will suffer from the fact that beta-lactams and fluoroquinolones coselect res

149 nd of blends, being one of them based on the fact that both diacylglycerol (DAG) and free fatty acids

150 The importance of this is illustrated by the fact that both loss- and gain-of-function mutations in P

151 initial stage distribution, highlighting the fact that both of these demographic features should be c

152 The fact that both the data of the Florence plague and those

153 impacts of stimulation, and underscores the fact that both the stimulation site, and, crucially, the

154 The latter observation highlights the fact that Brown-Zak fermions are Bloch quasiparticles pr

155 e to comparable static networks, despite the fact that bursty interaction patterns generally impede c

156 value of these findings is signified by the fact that CAMK4 is increased in podocytes of patients wi

157 The fact that CD8(+) memory T cells can have features of bot

158 l constriction, and this likely reflects the fact that central vision benefits most from the increase

159 Given the fact that cerebellar atrophy is seen in other IGDs, flow

160 chromatography separation efficiency and the fact that CI is a soft ionization technique that yields

161 Despite the fact that deep learning has achieved remarkable success

162 in toxicity between both groups, despite the fact that dexamethasone was omitted in the FMD group.

163 ical recombination events is hampered by the fact that driver genes are often expressed in both proge

164 Perhaps less familiar to clinicians is the fact that drugs can also trigger other arrhythmias, incl

165 ntinuum with no gaps or overlaps despite the fact that each valve, secreted by 2 mantle lobes, may pr

166 taking more strongly into consideration the fact that efficiency considerations are a key driver of

167 Progress in the area is hindered by the fact that error rates of conventional sequencing technol

168 ing and 2) this flexibility results from the fact that every single gene of the GRN possesses its own

169 amiliarity and recollection feelings and the fact that expectations determine how one recognizes prev

170 ed probability for boys, possibly due to the fact that frequency of carbohydrates consumption do not

171 e so-called "gender-equality paradox" is the fact that gender segregation across occupations is more

172 red after global de-methylation, despite the fact that global CpG methylation drops to 10% in primord

173 esults provide explanations for the puzzling fact that growth of B. subtilis does not result in the s

174 re among the lowest on the periodic table, a fact that has led to an interest in developing chromopho

175 S were most affected by chipping, due to the fact that higher cutting forces were needed for the high

176 In keeping with the fact that HuR increased the abundance of adhesion molecu

177 This approach is based on the fact that if a wild-type protein is more stable than a m

178 iatives focus on raising awareness about the fact that implicit bias and subtle discrimination are wi

179 unreactive toward redox reactions due to the fact that in such cases two electrons from the coordinat

180 Motivated by the fact that in vitro membrane protein studies often requir

181 They cited the fact that Isaac Newton came up with his theory of gravit

182 or this are the toxicity of the heme and the fact that it acts as a hemolytic and pro-inflammatory mo

183 non-invasively from video is stymied by the fact that it is a hard computational problem.

184 nanoparticles are very limited, despite the fact that it is one of the most studied wide band gap se

185 Considering the fact that it is still currently a controversial debate w

186 should be interpreted with caution, and the fact that it was not always possible to determine whethe

187 The fact that juvenile and adult skulls in birds do share a

188 However, despite the fact that large databases of compounds exist, the abilit

189 s are experiencing a renewed interest in the fact that males and females differ in many anatomic, phy

190 This task is complicated by the fact that many diseases are heterogeneous at the molecul

191 , determination of MRD is complicated by the fact that many treated patients have persistent clonal h

192 ions of Antarctic waters than soils, and the fact that maximum in situ temperatures in water are lowe

193 The fact that mechanically ventilated patients fail to achie

194 Our results point to the fact that microvascular alterations can be identifiable

195 This is true despite the fact that mimicry of these gradients may be essential fo

196 g of parent aromatics, shedding light on the fact that monocyclic aromatics can also serve as the hit

197 g disparities in palliative care include the fact that much of the available data are cross-sectional

198 ompared with far) visual objects and (2) the fact that near objects are more frequently found in lowe

199 shing and toxic food sources for survival, a fact that necessitates a mechanism for associating taste

200 ion strength between two cells, ignoring the fact that neural systems are inherently time-variant sys

201 analytical approaches is exemplified by the fact that no two teams chose identical workflows to anal

202 ot appear to fully appreciate the remarkable fact that normal development in molluscs, especially sna

203 The fact that OHCs are required for high-frequency hearing b

204 the extended coverage is demonstrated by the fact that one of the datasets could not have been descri

205 uantify behavior at scale are impeded by the fact that our methods for measuring human behavior are t

206 The fact that our VRE outbreak was discovered through WGS su

207 een study design, analysis strategy, and the fact that outcomes may be related to family size.

208 Despite the fact that pegasparaginase is associated with unique toxi

209 Despite the fact that percolation theory does not completely describ

210 fundamental challenge, however, has been the fact that physiological HFOs associated with normal brai

211 to spindle assembly has been limited by the fact that physiologically relevant tubulins were not ava

212 The method relies on the fact that plant DNA should not be present in readily det

213 The fact that potential patient out-of-pocket costs might in

214 domain is critical for Swi6 association with FACT that precludes histone turnover to promote gene sil

215 a potential mechanism that might support the fact that primates exhibit greater neural integration ca

216 Given the fact that PRMT5, YBX1 and NF-kappaB are all among top cr

217 This is highlighted by the fact that secondary findings are produced in other domai

218 like states in the earliest animals, and the fact that severe sleep loss can be lethal.

219 This is supported by the fact that severity of periodontal disease (CAL) is assoc

220 s and their mutual relatives, leveraging the fact that sharing rates among these individuals differ a

221 are directed solely at neurons, despite the fact that signaling between immune cells, glia, and neur

222 I point out that despite the fact that social norms are commonly used to alleviate co

223 tructures of their environments, despite the fact that standard behavior-based estimates suggested no

224 Furthermore, the fact that supplementary food almost completely eliminate

225 The fact that TGs and SEs are the typical cargo of lipid dro

226 The fact that the 2 tumor entities do not differ in their so

227 By exploiting the fact that the antiferromagnetic order can be reconfigure

228 in their unfolding behavior, underlining the fact that the choice of dye attachment positions within

229 e an ideal therapeutic target if not for the fact that the complex is encoded by eight distinct genes

230 To close this gap, we take advantage of the fact that the conditional logistic regression model (i.e

231 imented abyssal seafloor is at odds with the fact that the faunal diversity in some abyssal regions e

232 Further taking advantage of the fact that the HPS model maintains sequence specificity w

233 Central to this formulation is the fact that the human brain and immune system are principa

234 It could have been overlooked due to the fact that the initial work-out with a barium swallow, ma

235 This method exploits the fact that the localized plasmon resonance (LSPR) of the

236 The process is complicated by the fact that the naphthyridine exists as a mixture of two a

237 ulations than the NHW population-despite the fact that the NHW population is larger-with a ratio of 4

238 gement, despite (or possibly because of) the fact that the outbreak is an unprecedented global threat

239 Despite the fact that the plasticity of the embryo in dealing with a

240 Despite the fact that the practical frequency-diverse cavity uses a

241 Despite the fact that the radical pair is identical in all of the tr

242 The fact that the reaction is carried out at ambient conditi

243 In spite of the fact that the same physical and topological rules are in

244 t targeting of kidney cancer arises from the fact that the secretion pathway enables ICG-PEG45 to be

245 Here, we exploited the fact that the temporal dynamics of thermal stimuli in na

246 Despite the fact that the tissue specimen contains a variety of mole

247 Despite the fact that the transcription factor ATOH1 is a master reg

248 ale-invariant topology, which quantifies the fact that their branching lies in between the two extrem

249 with neurodegeneration in recognition of the fact that these changes are likely to be upstream causes

250 The fact that these molecular machines are conserved through

251 Besides the fact that these molecules are harmful for patients, litt

252 The fact that they are cultured in vitro makes them easily a

253 sing a P < 0.05 filter must be inflated, the fact that they are smaller when replicated (reflecting r

254 ndling these oligomers is complicated by the fact that they often exhibit multiple conformations beca

255 tural applications is largely limited by the fact that they show strain-softening instead of strain-h

256 The fact that this prediction can be made with a simple mode

257 ood about dorsal horn circuitry, despite the fact that this region loses most of its normal input aft

258 Despite the fact that this reveals a mechanism by which evolution co

259 The fact that TR-1 repeats often co-occur with knob180 repea

260 This and the fact that Type III immunity can be provided by plasmid-b

261 ng geographic variation in incidence and the fact that virus alone is insufficient to cause disease,

262 The fact that we found a small, yet distinct, population of

263 The fact that we have so many materials opens many exciting

264 of SSB consumption data in Argentina and the fact that we were only able to model the possible benefi

265 oth technological limitations as well as the fact that well-known genes tend to gather more interest

266 challenge to understanding remapping is the fact that what counts as a ''context change'' has never

267 This case highlights the fact that, despite its life-threatening nature, it's pos

268 on single chromosome structures, missing the fact that, in the full nucleus, interactions between chr

269 This can be assigned to the fact that, increasing the oil phase volume, the interfac

270 COVID-19 pandemic is a harsh reminder of the fact that, whether in a single human host or a wave of i

271 This is due to the fact, that the efficiency for high wavelength resolution

272 strongly suggest that xestocyclamine A is in fact the enantiomer of ingenamine (+)-3.

273 antigen for anti-leukocyte antibodies is in fact the endothelium, which reframes our understanding o

274 From this fact the transport and thermodynamic phase diagram is re

275 In fact, the EMV cargo genes exhibited normal expression pa

276 In fact, the ERRbeta ligand-binding domain remains the last

277 In fact, the first vaccine candidate launched into clinical

278 In fact, the intake of those products with higher concentra

279 In fact, the main substrate classifier distinguishing selec

280 In fact, the majority of patients with metastatic cancer de

281 To illustrate this fact, the mean concentrations of 60 SVOCs (40 or 80 mug/

282 In fact, the more than 50 formulations currently in the mar

283 In fact, the presence of PM(1) in marine biota has never be

284 In fact, the SAWN-CD method generated a multiply charged pe

285 In fact, the skyrmion dynamics is dominated by the local en

286 In fact, the term "viral sepsis" has been recently coined t

287 The requirement for FACT then depends on the level of chromatin disruption o

288 In fact, there is only one paper exploiting polynorepinephr

289 In fact, these activities are crucial for proper DNA damage

290 dividuals in a family, assuming (contrary to fact) they are unrelated, and (2) improving its accuracy

291 In fact, this effect was stronger in blue tits compared to

292 In fact, those SFGs are found to be the main reason for the

293 o DNA repair, we propose that the ability of FACT to both destabilize and assemble nucleosomes allows

294 This fact, together with recent growth of oligomeric structur

295 In fact, two major hallmarks of cancer, loss of cell-to-cel

296 their use in patients with COVID-19, may, in fact, undermine their utility in the context of the trea

297 that the TMJ in higher order species are in fact vascularized.

298 In fact, VSG corrected hepatic triglyceride dysregulation i

299 In fact, washout of these chronically exposed cells for up

300 In fact, we find that SSTR2 moves from an intracellular com

301 In fact, we here show that most polyspermy-derived seeds ar

302 In fact, we mapped this phenotype to a 4-amino-acid differe