ライフサイエンスコーパス: factor I

1 eity was assessed by using the inconsistency factor (I (2)).

2 previously identified the Mammalian Cleavage Factor I-25 (CFIm25) (encoded by Nudt21 gene) as a maste

3 The LEAFY COTYLEDON1 (LEC1) transcription factor is a central regulator of seed development, becau

4 The p53 transcription factor is a critical barrier to pancreatic cancer progre

5 One complicating factor is a high rate of comorbidity between cocaine and

6 hroid-derived 2)-like 2 (Nrf2) transcription factor is a key regulator of the cellular stress respons

7 The MITF transcription factor is a master regulator of melanocyte development a

8 The androgen receptor (AR) transcription factor is a master regulator of normal glandular homeost

9 g that astrocytic brain-derived neurotrophic factor is a potent protectant in the IC.

10 Granulocyte-macrophage colony-stimulating factor is a potential therapeutic target to reduce esoph

11 led 100S ribosomes) by hibernation-promoting factor is a widespread survival strategy among bacteria.

12 Vif (viral infectivity factor) is a protein that is essential for the replicati

13 Progranulin (PGRN), a secreted growth factor, is a key regulator of inflammation and is geneti

14 2/SLUG, a metastasis-promoting transcription factor, is a labile protein that is degraded through the

15 X20, a B-box (BBX) zinc-finger transcription factor, is a positive regulator of carotenoid accumulati

16 ention of MCI by identifying modifiable risk factors is a complementary and effective strategy.

17 mes with genetic variation and environmental factors is a core pursuit in biology and biomedicine.

18 Deregulation of transcription factors is a frequent occurrence in CRC, and the accompa

19 d function of metal-responsive transcription factors is a fundamental aspect of metallobiochemistry a

20 ommon complications based on individual risk factors is a graphical template for obtaining patient in

21 Rapid expression of critical stress response factors is a key survival strategy for diseased or stres

22 pounding effects of non-climate soil forming factors is a nontrivial challenge that must be overcome

23 sion reprogramming directed by transcription factors is a primary gene regulation underlying most asp

24 modification of intrinsic immune restriction factors is a promising and nontoxic approach for improvi

25 roving the evidence base for modifiable risk factors is a research priority.

26 ictors of future-specific affective lability factors is a step toward identifying objective markers o

27 etabolism and express regenerative paracrine factors is a strategy to treat vasculopathies and to pro

28 rm birth in combination with other perinatal factors is a strong risk factor for LRD, suggesting that

29 sed by air pollution and other environmental factors, is a new entity in respiratory disorders.

30 tiation-related transcription factor nuclear factor I-A (NFI-A) controls MDSC expansion during sepsis

31 deletion of the transcription factor nuclear factor I-A (NFIA) in astrocytes in the adult brain resul

32 rocytes, we investigated the role of nuclear factor I-A (NFIA), a key transcriptional regulator of as

33 We assessed new proposed risk factors (i.a.

34 ike EGF repeat containing (Dner) and nuclear factor I/A (Nfia), that are each heavily expressed in AI

35 The factor is abolished by treating the crude platelet facto

36 Re-compaction of Von Willebrand factor is accelerated by intramolecular interactions and

37 After a transcription factor is activated and carries out its transcriptional

38 tion that inhibits the activity of virulence factors is activated by host-factor-dependent acyl-adeny

39 The best described risk factor is acute enteric infection, but irritable bowel s

40 ce shows that the burden of behavioural risk factors is affected by socioeconomic position within LLM

41 and metal-dependent expression of virulence factors is also discussed.

42 osphorylation of the NF-kappaB transcription factor is an important regulatory mechanism for the cont

43 The PRH/HHEX transcription factor is an oncogenic driver in cholangiocarcinoma that

44 Unexpectedly, the transcription factor is an ortholog of the stomatal regulator AtMUTE,

45 on tumor cells in response to environmental factors is an important determinant of the ability of th

46 of RNA editing in response to environmental factors is an uncommon phenomenon.

47 B2 cells produced factor I and C3 and autophosphorylated CD19.

48 3' end processing factors, such as cleavage factor I and cleavage and polyadenylation specificity fa

49 with reduction of tumor insulin-like growth factor-I and vascular endothelial growth factor.

50 r peak regions, assuming that the same scale factor is applicable to both background and peak regions

51 A two-fold decrease in journal impact factor is associated with an average increase of 0.020 i

52 ease or decrease) in specific meteorological factors is associated with an increase in activity of sp

53 Absence of 3 common shared risk factors is associated with compression of morbidity of N

54 Since the TetR family of transcription factors is associated with multidrug resistance, our aim

55 in the signaling of insulin and other growth factors, is associated with AD neuropathology and lower

56 This 'master regulator' transcription factor is at the top of the hierarchy of the transcripto

57 o-fibrotic insults and that this circulating factor is attenuated in aged mice.

58 cleoid-associated proteins and transcription factors is blurred and that they likely share common ori

59 uring one burst as long as the transcription factor is bound to DNA, and bursts terminate upon transc

60 oad range of extracellular stimuli by growth factors is capable of activating EGR mediated transactiv

61 his disease is multifactorial, but a primary factor is cariogenic microorganisms such as Streptococcu

62 diseases, assessing the risk due to genetic factors is challenging because it requires knowledge of

63 e variability of refinery subprocess release factors is characterized using log-normal distributions

64 F2alpha), a conserved translation initiation factor, is clock controlled in Neurospora crassa, peakin

65 One is the reduced mass, and the other factor is cluster binding energy between an ion and a ne

66 C3bBb decay-accelerating activity (DAA) and factor I cofactor activity (CA).

67 Region 4 of the sigma70-family primary sigma factors is commonly used by transcription factors for ge

68 e traits, including the role of genetic risk factors, is complex and poorly understood.

69 lasticity accommodated by certain regulatory factors is conserved, despite substantial change in the

70 with Fe(II)aq using published fractionation factors, is consistent with our resulting delta(56)FeNaA

71 One such potential factor is contact order (CO), which is the average separ

72 fabrication of cardiac tissue, an important factor is continuous measurement of its contraction feat

73 The PBX1 homeodomain transcription factor is converted by t(1;19) chromosomal translocation

74 ulation, the reduced activity of coagulation factors is counterbalanced by an increase in factor VIII

75 The SOX2 transcription factor is critical for neural stem cell (NSC) maintenanc

76 Here, we define that the Prrx1 transcription factor is critical for tuning CAF activation, allowing a

77 levels in erythroid cells, and loss of both factors is critical for Pu.1 down-regulation during term

78 irected repression of multiple transcription factors is critically important for the establishment of

79 Activation of NF-kappaB transcription factors is critically required for Treg cell development

80 Nrf2 transcription factor is crucial for cytoprotective response, whereas K

81 debate, even though an understanding of this factor is crucial for experimental data on disease modif

82 The Sox6 transcription factor is crucial for terminal maturation of definitive

83 controlling the activation of transcription factors is crucial for physiology.

84 den of cancer attributable to different risk factors is crucial to inform and improve cancer preventi

85 impermeable inhibitor of one of the cleaving factors is currently being trialed as an antithrombotic

86 How the brain processes these factors is currently unknown.

87 The most potent H. pylori virulence factor is cytotoxin-associated gene A (CagA), which is t

88 Whether influence by irrelevant factors is debunking depends on the mechanisms through w

89 hat of topoisomerase 1, an R-loop preventing factor, is decreased at R-loop-enriched regions of IFNG

90 sonance forms, we argue that this underlying factor is defined as the difference in energy between th

91 diode with a dynamically controlled ideality factor is demonstrated.

92 mbinant human granulocyte colony stimulating factor is demonstrated.

93 This diagnostic, called the seed factor, is dependent only on observable quantities, and

94 Thus, regulation of transcription by these factors is dependent on divergent N-terminal domains.

95 )13, a nonsecreted, X-linked, FGF homologous factor, is differentially expressed in adipocytes in res

96 ibility via the recruitment of transcription factors is difficult to study in the context of the nati

97 rpose this model to incorporate these "human factors" is discussed in detail and suggestions offered.

98 Uncertainty in effect factors is dominated by the exposure-response shape, bac

99 IOP and at least 1 additional glaucoma risk factor (i.e., they were high-risk patients), only a rela

100 orts aimed at understanding the key limiting factor, i.e., the nature of the PGM-free active site, ar

101 found to be coupled with more classical risk factors (i.e. age, gender, race/ethnicity) to create a m

102 expression of four cardiogenic transcription factors (i.e. Gata4 (G), Hand2 (H), Mef2c (M), and Tbx5

103 In contrast, biological factors (i.e. plant productivity and soil bacterial dive

104 also determined the effects of environmental factors (i.e. soil nutrients, moisture, and phenolics) a

105 ly significantly associated with demographic factors (i.e., % people of color, % poverty, and % low e

106 The numbers of patients with 0, 1, 2, or 3 factors (i.e., antiplatelet therapy, thrombopenia [< 150

107 and outperforms acclimation of other single factors (i.e., Ea or DeltaS alone); (2) multifactor scen

108 factors, lines of responsibility and 'other' factors (i.e., funding), were also frequently reported b

109 tors, supervision and leadership and 'other' factors (i.e., funding, planning for role integration).

110 d via nuclear reprogramming by transcription factors (i.e., induced pluripotent stem cells, iPSCs) or

111 nt to which sleep disturbances serve as risk factors (i.e., longitudinal correlates) for suicidal tho

112 study design and adjustment for confounding factors (i.e., socioeconomic factors, other substance us

113 of coronary heart disease (CHD) and its risk factors (i.e., type 2 diabetes, adiposity, blood pressur

114 CASP13 experiment and identified several key factors [i.e. deep learning technique, multiple sequence

115 is and expression of angiogenesis-associated factors, i.e. CD31, VEGF, VEGF receptor II, phosphor-ERK

116 f how combinatorial binding of transcription factors, i.e. the regulatory grammar, drives enhancer ac

117 However, our results suggest that other factors, i.e., metabolic capabilities and spatial moveme

118 Sensing performance factors, i.e., sensitivity, a detection limit and respon

119 activator protein-1) family of transcription factors, is emerging as a major gatekeeper against oxida

120 d entirely of adult nonlaboratory-based risk factors is equivalent to an approach that additionally i

121 Negative elongation factor is essential for endometrial function.

122 The PLZF transcription factor is essential for osteogenic differentiation of hM

123 smid-encoded pGP3, a genital tract virulence factor, is essential for Chlamydia muridarum to colonize

124 that Bcl11b, known as a T-lineage commitment factor, is essential for proper expression of ThPOK and

125 various factors and that understanding such factors is essential for more control of residual pestic

126 led that O-linked glycosylation of chromatin factors is essential for the transcriptional repression

127 obiota and colonization resistance, and risk factors is essential to reduce the toll of these infecti

128 A careful consideration of confounding factors is essential, since interventions for AF will be

129 , for a given query image sequence a scaling factor is estimated to match a reference image sequence

130 plants are produced when a TCP transcription factor is expressed in axillary meristems and binds to t

131 ent individuals without the traditional risk factors is extremely rare clinical phenomenon.

132 pecific zinc finger-containing transcription factor is for the first time found to be expressed in GI

133 thin wire and having the highest possible Q-factor is found by numerical optimization.

134 quired functions downstream of transcription factors is hampered by the large number of genes whose e

135 The rarity of failures argues that safety factor is high under physiological conditions, yet the o

136 re the incidence of perinatal and early risk factors is high.

137 As this factor is highly expressed in the stem and proliferative

138 after controlling for g This spatial ability factor is highly heritable (69%).

139 Here, we show one such stabilizing factor is host-plasmid coevolution under antibiotic sele

140 We hypothesize that an important factor is how people treat coyotes; in the rural area co

141 melanosomes is biased by biotic and abiotic factors is, however, unknown.

142 Circulating insulin-like growth factor I (IGF-I) is positively associated with the risks

143 esent with reduced serum insulin-like growth factor I (IGF-I).

144 wth, perhaps mediated by insulin-like growth factor I (IGF-I).

145 etal growth by modifying insulin-like growth factor-I (IGF-I) bioavailability.

146 ical recovery, and serum insulin-like growth factor-I (IGF-I) may mediate this effect.

147 rmone and, consequently, insulin-like growth factor I (IGF1), most often by a pituitary adenoma.

148 nces about 1 treatment effect such that each factor is immune to some bias that would invalidate the

149 The GATA family of transcription factors is implicated in numerous developmental and phys

150 gulfment, and determined that serum response factor is important for MFG-E8 production in myofibrobla

151 ssociated with a potentially modifiable risk factor is important.

152 airway (UA) obstruction based on pharyngeal factors is important for obstructive sleep apnea (OSA) e

153 ell-type proportion estimates as confounding factors is important for reducing false associations bet

154 ography, recombination and other confounding factors is important, and use of a range of methods in c

155 the Ni catalyst and the base, due to steric factors, is important for avoiding catalyst inhibition.

156 lization in children without predefined risk factors is, in part, mediated at the antiviral gene leve

157 Unexpectedly, spreading of these three factors is inextricably linked.

158 cells and controlled-release of programming factors is innovative, and will facilitate the developme

159 e propensity is affected by sociodemographic factors is invaluable for predicting where outbreaks are

160 Here, the biskyrmion form factor is investigated in single- and polycrystalline-Mn

161 hogen, and its Lys-gingipain (Kgp) virulence factor is involved in the pathogen-host interaction thro

162 One important virulence factor is its urease enzyme, which requires nickel to be

163 currence of such failures argues that safety factor is just high enough to ensure near-perfect reliab

164 A better understanding of host protective factors is key to developing an effective remedy.

165 raveling the interplay between these genetic factors is key to the discovery of new biomarkers and tr

166 iversally conserved transcription elongation factor is known as Spt5 in archaeal and eukaryotic organ

167 ng as the effect of temperature on retention factor is known, experimental conditions required to ach

168 sis AINTEGUMENTA (ANT), an AP2 transcription factor, is known to control plant growth and floral orga

169 NA occupancy of a polymerizing transcription factor is lacking, and such a description would have bro

170 Variance due to genetic factors is largely constant, but its share as a part of

171 ransplant, the effect size of common genetic factors is limited compared to clinical variables.

172 egulation of the gluconeogenic transcription factors is limited.

173 ysiological mechanisms supporting these risk factors is limited.

174 HOXB13, a homeodomain transcription factor, is linked to recurrence following radical prosta

175 NA sliding clamp and polymerase processivity factor, is loaded onto the primer-template junction by r

176 ven by the NF-kappaB family of transcription factors is lower in infected cells.

177 Cleavage factor I mammalian (CFIm) complex, composed of cleavage

178 Nuclear-cytoplasmic transport of oncogenic factors is mediated by Karyopherin proteins during cell

179 nvertase decay accelerator, and cofactor for factor I-mediated cleavage of C3b and C4b.

180 The gene encoding the RUNX1 transcription factor is mutated in a subset of T-cell acute lymphoblas

181 e significantly altered when the controlling factor is mutated.

182 scription factor and the expression of these factors is mutually exclusive because of cross-regulatio

183 ently, this essential translation initiation factor is nearly twice as abundant in male as in female

184 ough FAK and cofilin (actin depolymerization factor) is necessary to promote synaptic growth during t

185 IF-1alpha), an O(2) -sensitive transcription factor, is necessary in the NTS for normal VAH.

186 t consideration of all of the aforementioned factors is necessary to account for the observed photopr

187 Identification of early and modifiable risk factors is necessary to advance the screening and interv

188 Identification of modifiable risk factors is needed for interventions aimed at reducing ri

189 tifying hemolytic uremic syndrome (HUS) risk factors is needed to guide care.

190 standing of the long-term influence of these factors is needed to prioritise public health investment

191 r evidence of the relationship and modifying factors is needed.

192 esearch examining barriers to care and other factors is needed.

193 The nuclear factor I (NFI) family of transcription factors plays an

194 e up-regulated by hypophosphorylated nuclear factor I (NFI), which is dephosphorylated by the phospha

195 Nuclear factor I (NFI)-type transcription factors regulate genes

196 The DUX4 transcription factor is normally expressed in the cleavage stage embry

197 ortantly, Ras activation by epidermal growth factor is not altered when IQGAP1 or IQGAP3 proteins are

198 , thereby indicating that this transcription factor is not only regulated by oxygen, but also by iron

199 , we demonstrate explicitly that the scaling factor is not uniform but is close to 1 for small mEPSCs

200 lated DNA ligase IV, indicating that this co-factor is not utilized for re-adenylation and subsequent

201 marker; however, the impact of preanalytical factors is not well understood.

202 umid regions worldwide, the characterization factor is null, showing that in these cases soil saliniz

203 An important modifiable AD risk factor is obesity and its associated metabolic dysfuncti

204 The 3D safety factor is obtained through the approximation function an

205 on and spread through the usurpation of host factors is of primary importance for the development of

206 The dynamical structure factor is one of the experimental quantities crucial in

207 Mode volume overlap factor is one of the parameters determining the sensitiv

208 chromosome-linked male determining factor (M-factor) is one of a diverse array of sex determination m

209 -oncogene in the p53 family of transcription factors, is overexpressed in squamous cell carcinoma (SC

210 /EBPbeta, a key pro-adipogenic transcription factor, is PARylated by PARP-1 on three amino acids in a

211 .402C>G (p.C134W) in the FOXL2 transcription factor is pathognomonic for adult-type granulosa cell tu

212 of genetic susceptibility and environmental factors is poorly understood.

213 VP35 function is regulated by host cellular factors is poorly understood.

214 owever, the relative importance of these two factors is poorly understood.

215 t that chromatin access of on-target pioneer factors is primarily driven by the protein-DNA interacti

216 The index of NCD risk factors is projected to drop to 38.8 by 2025.

217 dence has implicated the insulin-like growth factor I receptor (IGF-IR) in the pathogenesis of this d

218 Inhibition of the insulin-like growth factor I receptor (IGF-IR) is a new therapeutic strategy

219 marker, we analyzed the insulin-like growth factor I receptor (IGF1R), a promising target, but a mar

220 education of "Facial cleanness" and related factors is recommended to increase knowledge of the moth

221 The availability or activity of the sigma factor is regulated by complex regulatory circuits, the

222 activity of the mitochondrial transcription factors is regulated to prevent DNA binding at inappropr

223 r of genes whose expression changes when the factor is removed from a specific tissue and the numerou

224 cription activator (RTA) viral transcription factor is required for the induction of lytic viral gene

225 r data identify that the NR4A3 transcription factor is required to guide the fate of monocytes toward

226 We found that VdCmr1, a transcription factor, is required for the melanin production and incre

227 f enhancers by tissue-specific transcription factors is required for NICD to confer synchronized and

228 mbinatorial expression of Brn3 transcription factors is required for the development of cell-specific

229 r the continued activity of these pioneering factors is required throughout zygotic genome activation

230 Our findings indicate that a combination of factors is required to sensitize these regions.

231 , neuronal input, likely via neuron-supplied factors, is required for generation of differentiated ta

232 hat the subtle interplay between these three factors is responsible for (i) the formation of non-IPR

233 .4G186800, which encodes a NAC transcription factor, is shown to be associated with early fruit matur

234 -differentiating factor exists and that this factor is Sox8.

235 e pioneer forkhead box (FOX)A2 transcription factor is specifically expressed in the glands of the ut

236 oughly half the mRNA for certain translation factors is specifically directed in granules or translat

237 nsive analysis of contributing environmental factors is still an open challenge.

238 uture climate and its associated controlling factors is still missing, despite its high sensitivities

239 and their relationship to underlying genetic factors is still poorly understood.

240 he coincident, combined binding of all three factors is strongest at the HAS1pr-TDA1pr locus and is a

241 tment of TIP60 and ATM, two key proximal HDR factors, is substantially impaired at DNA breaks, with r

242 xpression of a testis-specific transcription factor is sufficient to co-opt somatic transcriptional m

243 ing motif for a key regulatory transcription factor is sufficient to open chromatin, and classify set

244 of the fluid, and hence of the mobile repair factors, is sufficient to account for the extent of DNA

245 nd granulocyte-macrophage colony-stimulating factor (I/T/DIN/GM-CSF) demonstrated activity in patient

246 ent of left-right (LR) asymmetry, a limiting factor is that most animals are ordinarily invariant in

247 One important factor is that the foot's ability to exert torque on the

248 es only few steps; however, an indispensable factor is the addition of a locking substance into the b

249 osed mediator, the direct effect of the risk factor is the change in the outcome resulting from a cha

250 e that one unconsidered but likely important factor is the energetic demand of brain development, whi

251 One likely contributing factor is the genetic heterogeneity of patients that mig

252 In Europe, a key factor is the geography and history of climate change th

253 acerbation of anemia, one major contributing factor is the impairment of erythropoiesis.

254 We show that one such factor is the kinesin KIF4A, which is present along the

255 A major contributing factor is the long-term persistence of a reservoir of la

256 One important environmental factor is the metabolic output of human gut microbiota.

257 ptor alpha, and targeting this transcription factor is the most effective therapy for this subtype.

258 We defined which factor is the most significant determinant of SR and we

259 ing of the second-order non-linear structure factor is the source of this contrast and develop a mode

260 iled computations suggest that the governing factor is the strength of electronic coupling between pa

261 nistic bacterium of which the main virulence factor is the Type III Secretion System.

262 dds to the risk of lymphedema, the main risk factor is the type of axillary surgery used.

263 One complicating factor is the variable amounts of Schwann cells (SCs) in

264 ar transformation by oncogenic transcription factors is the ability to define their direct gene targe

265 One of these factors is the nsp13 helicase.

266 One of these factors is the presence and titers of neutralizing Abs (

267 One of these host factors is the RNA lariat debranching enzyme (Dbr1), whi

268 One of its key antifungal virulence factors is the type IV pili that are required for twitch

269 ly EsxBA and/or other codependently secreted factors) is the negative regulator of miR-147.

270 r, clinicians are currently limited by three factors: (i) the current behavioural repertoire of minim

271 The IRF-3 transcription factor is then recruited to the signalling complex and a

272 trol mediated by the circadian transcription factors is thought to be the main driver of mammalian ci

273 The lack of exposure to these factors is thought to prevent proper education and train

274 The coordinated action of soluble factors is thought to trigger the mobilization of stem c

275 Disruption of nuclear factor I transcription factors, which maintain and resto

276 One of the least controllable factors is transport and storage, but it is often not ta

277 luding glucose, insulin, insulin-like growth factor I, triglycerides, cholesterol, cortisol, and lept

278 response but the contribution of other host factors is unclear.

279 lesi cases, but the role of individual-level factors is unclear.

280 when controlling for other known prognostic factors, is unclear.

281 tudies suggest that one possible confounding factor is underlying maternal psychiatric disorders.

282 glutamate levels can be explained by genetic factors is unknown, and if glutamate can serve as a mark

283 activation by these TetR-type transcription factors is unknown, though LuxR DNA binding sites that l

284 nephros (AGM) microenvironment produce these factors is unknown.

285 ut how this relates to specific genetic risk factors is unknown.

286 ent to which this can be offset by lifestyle factors is unknown.

287 directed by lineage-specifying transcription factors is unknown.

288 expression of T helper (TH) lineage-defining factors is unknown.

289 portion of breast cancers explained by these factors is unknown.

290 w these roles are regulated by transcription factors is unknown.

291 its effects and whether it requires any host factors is unknown.

292 modulated by both genetic and environmental factors, is unknown.

293 th factor (VEGF)-C, a potent lymphangiogenic factor, is up-regulated in endometriotic cells and contr

294 of Ovol1 (encoding ovo-like 1 transcription factor) is upregulated in psoriatic skin, and its deleti

295 The scaling factor is used to adjust the CMIP5 model-projected PW ch

296 As this factor is usually elevated in cirrhosis, the agent lacks

297 Because extricating these two factors is usually unfeasible, it has been common to ass

298 The Sox2 transcription factor is well known for its roles in the development an

299 signaling via its phosphorylation by growth factors is well recognized, and we wondered whether they

300 The FOXA family of transcription factors is well understood to have pioneer capacity.