1 was not determined and is most likely multi-
factorial.
2 ent degrees of protection observed was multi-
factorial.
3 A
factorial (
2x2), double-blind, randomized clinical trial
4 This in vitro study comprised 2 parts (both
factorial 4 x 2), with 4 lesion types (erosion, abrasion
5 PSCs remains challenging given complex multi-
factorial actions at different stages.
6 as grown on a sandy loam soil while provided
factorial additions of N and CO2 .
7 rophages offers a first-step towards a multi-
factorial amenable IBD platform that could be scaled up
8 The multiple
factorial analysis demonstrated that the most important
9 articipants were determined by using two-way
factorial analysis of covariance with age adjustment.
10 larify the mechanisms involved in a multiple
factorial analysis of the data set.
11 Factorial analysis showed no interaction between cash an
12 Factorial analysis suggested a synergistic effect of com
13 Factorial analysis suggested a synergistic effect of com
14 A
factorial analysis was carried out to evaluate the influ
15 In addition, multiple
factorial analysis was performed to explore potential re
16 In a 4 x 4
factorial analysis, exposure to increasing genetic risk
17 ourier transform infrared spectromicroscopy,
factorial analysis, principal component analysis, and st
18 es in the control group in a single flexible
factorial analysis.
19 solidification of organic drop: a fractional
factorial and a central composite design.
20 Results from combined
factorial and conjunction analyses indicated that the po
21 Through both
factorial and correlational analyses, we show a signific
22 The fractional
factorial and Doehlert designs for optimization of a slu
23 d by a multivariate approach (two-level full
factorial and Doehlert designs).
24 increase until week 16 (p < 0.0001, two-way
factorial ANOVA).
25 increase until week 16 (p < 0.0001, two-way
factorial ANOVA).
26 ts (ambient, +1.7 degrees C, +3.4 degrees C)
factorial at two sites.
27 o) in a randomized, placebo-controlled, full-
factorial,
between-subjects design.
28 Defining multi-
factorial biomarker algorithms for immunotherapy require
29 Glaucoma is a multi-
factorial blinding disease in which genetic factors play
30 Such estimates are also needed for the
factorial calculation of AA requirements.
31 clear that mitophagy is a complex and multi-
factorial cellular response that depends on tissue, ener
32 ters were optimized by using a half-fraction
factorial central composite design (CCD).
33 We implemented a fully
factorial climate manipulation of warming (+2.5-3.0 degr
34 ARTICIPANTS: Randomized, placebo-controlled,
factorial clinical trial among 120 patients aged 60 year
35 Randomized 2 x 2
factorial clinical trial in neonates (>/=36 weeks' gesta
36 conducted a repeated cross-sectional, 2 x 2
factorial,
cluster-randomised controlled trial, in which
37 The study was a prospective 2 x 2
factorial,
cluster-randomized trial in 467 FT-LBW infant
38 SHINE is a proof-of-concept, 2 x 2
factorial,
cluster-randomized, community-based trial in
39 At each site we implemented a fully
factorial combination of 2.5-3 degrees C warming and 20%
40 ns), and Cascades frogs (Rana cascadae) to a
factorial combination of two pathogen treatments (Bd(+),
41 Optimized
factorial combinations have been found to be 0.5mm layer
42 ore and piscivore over depth and time across
factorial combinations of latitude (0-70 degrees ), turb
43 intended to allow users to search for multi-
factorial combinations of species' omics properties.
44 supplements were given for 16 wk in a 2 x 2
factorial comparison against placebo.
45 A cluster-randomized
factorial controlled trial with two replications was con
46 Keratoconus (KC) is a multi-
factorial corneal ectasia with unknown etiology affectin
47 We used
factorial correspondence analysis to describe categories
48 In a full
factorial crossed design with parental and offspring JA
49 acellular viscoelasticity, generating a full
factorial dataset on 5 cell lines in 2 ECMs subjected to
50 extraction procedure was optimized by a 3(2)
factorial design (%HCl in methanol, temperature, and tim
51 he hydrogels using a Resolution-V fractional
factorial design (2 (V)(5-1) FFD), followed by response
52 A fractional
factorial design (2(7-2)) with a centre point was used t
53 ptimised using the combination of fractional
factorial design (FFD) and central composite design (CCD
54 mixtures using MALDI-TOF-MS with fractional
factorial design (FFD) and Pareto optimality.
55 A full
factorial design (FFD) consisting of four independent va
56 We mated beetles in a 2 x 2
factorial design (males with or without foliage paired w
57 adding the vectors at two levels (fractional
factorial design 2(VI)) to a de-aromatised aged red wine
58 bel, non-inferiority randomized trial with a
factorial design among treatment-experienced people with
59 A
factorial design analysis was carried out to reduce the
60 The method was optimized using a full
factorial design and Doehlert Matrix.
61 3 g/L of drinking water) was determined by a
factorial design and preneoplastic endpoints in chemical
62 f ox-GCE/AuNPs-ARG/IgM was optimized through
factorial design and response surface methodology.
63 ember 2011) in stage III NSCLC using a 2 x 2
factorial design and stratified by histology, positron e
64 ed a randomized, placebo-controlled, reduced
factorial design and was double-blind with respect to su
65 olives, were investigated by applying a full
factorial design approach (4 oxygen levels x 4 storage t
66 ANTS: Randomized clinical trial with a 2 x 2
factorial design conducted among 1312 adults with type 2
67 control trial, 3 groupsx4 time points mixed
factorial design conducted from July 2015 to March 2016.
68 Response variables in the full
factorial design consisted of absorption intensity, sign
69 A
factorial design experiment was conducted and the effect
70 A full
factorial design experiment was defined to develop aqueo
71 HR-CS FAAS) was optimized by applying a full
factorial design in two levels and the response surface
72 A full
factorial design in two levels was applied to evaluate t
73 ed, randomized controlled trial with a 2 x 2
factorial design including iron supplements (42 mg eleme
74 on step was performed using a two-level full
factorial design involving the following factors: pH of
75 The 2 x 2
factorial design led to 547 patients receiving prednisol
76 ion conditions were optimized by a 2(3) full
factorial design method.
77 ibitor and a statin with the use of a 2-by-2
factorial design minimizing differences in baseline char
78 trolled, open-label trial using a two-by-two
factorial design of 56 enumeration area clusters in the
79 e key transformation was optimized by a 2(2)
factorial design of experiment, highlighting the unique
80 To this end we used a two-level fractional
factorial design of resolution IV (2(IV)(7-3)).
81 nly RCTs with sample sizes >500 and a 2-by-2
factorial design or dichotomous primary outcomes were se
82 ross quartiles using an analysis of variance
factorial design testing for interaction effects, adjust
83 We conducted a trial with a 2-by-2
factorial design to assess the benefits of early antiret
84 models with and without eyespots in a 2 x 2
factorial design to avian predators in the field.
85 ith Cystic Fibrosis and assembled in a fully
factorial design to create simple microcosms.
86 double-blind, randomized trial with a 2-by-2
factorial design to evaluate the effect of treatment wit
87 bination of response surface methodology and
factorial design to optimize the variables: temperature
88 igated MRD in subjects randomized in a 2 x 2
factorial design to receive either high-dose methotrexat
89 6 years) were randomly assigned (1:1:1) in a
factorial design to receive lay counsellor clinic linkag
90 lacunar infarcts were randomly assigned in a
factorial design to target levels of systolic blood pres
91 The UK TACT2 trial used a 2x2
factorial design to test two hypotheses: whether use of
92 Randomized assignment in a 2 x 2
factorial design to vitamin D3 (2000 IU/d of cholecalcif
93 severe CKD through a pilot, randomized, 2x2
factorial design trial.
94 A randomized, phase II trial with a 2 x 2
factorial design was conducted to investigate the effect
95 A full
factorial design was used to assess the single and inter
96 A two level
factorial design was used to determine the effect of key
97 A five factor fractional
factorial design was used to identify the most significa
98 A 2(6-1)
factorial design was used to identify the significant va
99 A 2(4)
factorial design was used to simultaneously evaluate the
100 A 2 x 2
factorial design was used to test two hypotheses: (1) th
101 A quasi-experimental, 3x4
factorial design was used.
102 A
factorial design with a duplicate in the central point w
103 cesses and eXchanges (LPX) DGVM was run in a
factorial design with fire 'off' or 'on', CO2 at LGM (18
104 The study used a 2 x 2
factorial design with radiation dose as 1 factor and cet
105 We used a full-
factorial design with snakes from two divergent life-his
106 We used a 2 x 2
factorial design with the following factors: (i) the pre
107 Microcosms were subjected to a
factorial design with two levels of nutrient-induced div
108 l warming and altered precipitation (in full-
factorial design) on biocrust communities and compared t
109 By using a 2 x 2
factorial design, 2,914 participants were randomly assig
110 er-randomized controlled trial using a 2 x 2
factorial design, 76 CHCs were randomly assigned to deli
111 f two patch-level resource levels in a 2 x 2
factorial design, allowing us to assay colonization at b
112 ess vs. 12:12 h light:dark cycle) in a 2 x 2
factorial design, allowing us to elucidate potential pat
113 the other trial that was part of the 2-by-2
factorial design, and (iii) the sample size of the house
114 In this study with a 2-by-3
factorial design, conducted at 41 clinical centers, we r
115 They employ a full
factorial design, including both food supplemented and c
116 A full
factorial design, including different cycles, probe size
117 A 2 x 2
factorial design, including subliminal/supraliminal expo
118 AN ( 5 lux) for 9 weeks, then paired in full
factorial design, mated, and thereafter housed under dar
119 placebo-controlled trial, with a two-by-two
factorial design, of vitamin D(3) (at a dose of 2000 IU
120 placebo-controlled trial, with a two-by-two
factorial design, of vitamin D(3) (cholecalciferol) at a
121 In a 2 x 2
factorial design, participants were randomized to a targ
122 In a 2 x 2
factorial design, patients were randomized to genotype-g
123 In study 3, with the use of a 2 x 2
factorial design, subjects consumed a maize meal fortifi
124 ndomized controlled pilot trial with a 2 x 2
factorial design, subjects were randomized to withdrawal
125 Under optimized experimental parameters by
factorial design, the biosensor was applied to the volta
126 pain were randomly assigned, in a two-by-two
factorial design, to target levels of systolic blood pre
127 vestigated such an influence through a 2 x 2
factorial design, using attractiveness (high/low) of the
128 physicians from across Canada using a 2 x 2
factorial design, varied by infection source (undifferen
129 In a 2 x 2
factorial design, visual and auditory feedback on one's
130 As part of a 2-by-2
factorial design, we conducted a cluster-randomized tria
131 Applying a
factorial design, we investigated 4 groups of children a
132 In a trial with 2-by-2
factorial design, we randomly assigned 12,705 participan
133 Using a 2-by-2
factorial design, we randomly assigned 5177 patients at
134 Using a 2-by-2-by-2
factorial design, we randomly assigned participants with
135 In a trial with a 2-by-2
factorial design, we randomly assigned patients who were
136 In an international trial with a two-by-two
factorial design, we randomly assigned patients with atr
137 CIR and NIR were evaluated using a balanced
factorial design, with each intake factor at 2 levels (p
138 rculating flumes in a central composite face
factorial design.
139 on the recovery was examined by experimental
factorial design.
140 functionally relevant context using a fully
factorial design.
141 mumol/L) and DLM (0, 100, 300 mumol/L) in a
factorial design.
142 eld of DPGG were optimized using a 3(3) full
factorial design.
143 e we describe a novel generalized fractional
factorial design.
144 3, randomised, open-label study with a 2 x 2
factorial design.
145 ntration was determined using a two variable
factorial design.
146 city of extracts were investigated by a full
factorial design.
147 eness, cluster-randomised trial with a 2 x 2
factorial design.
148 Randomized clinical trial with 2 x 2
factorial design.
149 polydextrose or placebo for 50 d in a 2 x 2
factorial design.
150 igated as independent variables in two level
factorial design.
151 ith leaf removal or untreated control in two-
factorial design.
152 nd gradations of natural sunlight in a fully
factorial design.
153 interleukin 15 (IL-15) priming using a 2 x 2
factorial design.
154 ty of food for Tree Swallow chicks in a full
factorial design.
155 eaxanthin (2 mg) vs placebo were tested in a
factorial design.
156 r doses or weekly for 12 doses using a 2 x 2
factorial design.
157 f each the factor were assessed using a full
factorial design.
158 roximately 50 mg l(-1) NO3 (-) -N) in a full
factorial design.
159 domly allocated to one of 4 diets in a 2 x 2
factorial design.
160 (1200 mg), both, or neither in a partial 2x2
factorial design.
161 lycatchers (Ficedula hypoleuca) using a full
factorial design.
162 extraction conditions were screened using a
factorial design.
163 ry uncertainty from decision difficulty in a
factorial design.
164 s from expected trial transitions within our
factorial design.
165 es (pCO(2); 650 and 1050 uatm) using a fully
factorial design.
166 expressed at different levels according to a
factorial design.
167 mized conditions were established after full
factorial design: digestion time of 14 min, concentratio
168 Prospective, randomized, 2 x 2
factorial-
design trial with explicit methods (July 1, 20
169 We conducted duplicated
factorial designed experiments producing tangerine tomat
170 Two-level fractional
factorial designs remain the preferred approach due to h
171 ates the potential of generalized fractional
factorial designs to be applied in many other areas of a
172 issues: noninferiority trials, the value of
factorial designs, the importance and challenges of stra
173 nalogous to a fold-over in two-level reduced
factorial designs.
174 on of which employed a sequence of different
factorial designs.
175 on and phase separation were optimized using
factorial designs.
176 atory bowel disease (IBD) is a complex multi-
factorial disease for which physiologically relevant in
177 In this 2 x 2
factorial,
double-blind placebo-controlled trial, 457 le
178 In this randomized, 2 x 2
factorial,
double-blind trial, 2400 infants were randoml
179 odian women screened as anemic.In this 2 x 2
factorial,
double-blind, randomized trial, nonpregnant w
180 an interaction effect on growth responses in
factorial eCa x temperature experiments.
181 ere were no significant temperature, time or
factorial effects for all color parameters during storag
182 Therefore, the Ecotox
FACTORIAL enables harmonized assessment of the endocrine
183 ibe a multiplexed reporter assay (the Ecotox
FACTORIAL)
enabling parallel assessment of compounds' ef
184 (2+), Al(3+), Cr(3+), Fe(3+), and Ga(3+)) in
factorial excesses to anthocyanin concentration (0-500x)
185 We used a
factorial experiment in mesocosms wherein we crossed hig
186 A 12-week
factorial experiment was conducted to investigate the in
187 ape pomace was extracted in hot water, and a
factorial experiment was used to evaluate polysaccharide
188 We show, using a long-term
factorial experiment, that plant diversity loss alters t
189 LDV and SOF were evaluated using a fully
factorial experimental design in the BelloCell system.
190 ers for chemical profiling from a multilevel
factorial experimental design using 2 factors and more t
191 Using a multi-
factorial experimental design we found that growth phase
192 eratrol on DEP-exposed human lung cells in a
factorial experimental design.
193 me, pH and temperature) were optimized using
factorial experimental design.
194 ically important olive varieties with a full
factorial experimental design.
195 y of growth factor responsiveness based on a
factorial experimental design.
196 A total of 16 treatments reflected a 4 x 4
factorial experimental design.
197 o identify the significant factors, two full
factorial experimental designs were built, each containi
198 A fully
factorial experimental manipulation of predator and para
199 We utilized a high-throughput full-
factorial experimental system and the model photosynthet
200 Using null-models and meta-analyses of 22
factorial experiments in herbaceous plant communities ac
201 study of grassland species, we used two full
factorial experiments to independently vary SR (one or f
202 nction and highlight the need for long-term,
factorial experiments.
203 that are frequently used for screening (full
factorial,
fractional factorial, Plackett-Burman Design)
204 rom homologous challenges as well as a multi-
factorial heterologous risk enhancement.
205 Inference in these so-called
Factorial HMMs has a naive running time that scales as t
206 a Python package for fast exact inference in
Factorial HMMs.
207 of which is non-functional and confers mono-
factorial inheritance of sterility.
208 A 2 x 2
factorial intention-to-treat analysis with the use of a
209 will help to avoid incorrect conclusions in
factorial interaction studies (genotype x genotype, geno
210 The Ecotox
FACTORIAL is a single-well assay comprising a set of spe
211 A 32-member fraction
factorial library is designed that simultaneously pertur
212 This is compared to a 64-member full
factorial library just varying expression (0.64 Mb of DN
213 , and trends over time were analyzed using a
factorial logistic regression.
214 d simulated predation threat in a two-by-two
factorial long-term experiment.
215 A
factorial MANCOVA was used to detect interactions betwee
216 ommunities of wood-decomposing fungi using a
factorial manipulation of fungivore (Folsomia candida) p
217 Here we use a large-scale
factorial manipulation to assess the extent to which bir
218 In the other matriline, a separate
factorial mating assay of cured and infected spiders dem
219 mount vs. concentration, we expose rice to a
factorial matrix varying the dose of nitrogen (N) and wa
220 gests the possibility of a combined or multi-
factorial mechanism underlying the female fertility - bi
221 l infarction) among each group using a 2 x 2
factorial mendelian randomization study design.
222 the water flea, Daphnia magna, using a full
factorial mesocosm experiment.
223 The full
factorial model revealed a significant interaction betwe
224 pared to a fixation baseline contrast, and a
factorial model with Group as between-subject and Drug a
225 nd 2-AG ANCOVAs were calculated using a full
factorial model, with condition (reward > control, loss
226 Full
factorial models were used to assess cord atrophy in par
227 In particular, it highlights their
factorial nature - both in terms of deep hierarchies ove
228 Here, we report results from a standardized
factorial nutrient addition experiment, in which we adde
229 Here we present the results of full-
factorial nutrient amendment experiments conducted at th
230 r seedlings nested within a replicated 15-yr
factorial nutrient enrichment experiment (nitrogen, N; p
231 In this
factorial open-label trial conducted in Uganda, Zimbabwe
232 In this
factorial,
open-label trial, we randomly assigned Uganda
233 We did an international, partial-
factorial,
open-label, blinded-endpoint trial of thrombo
234 CALGB 40603 (Alliance), a 2 x 2
factorial,
open-label, randomized phase II trial, evalua
235 In this
factorial,
open-label, randomized, controlled trial, we
236 the results obtained using traditional full
factorial optimization technique and a TEG configuration
237 of cytokines in "ideal" responses; the multi-
factorial origins that can drive these responses to beco
238 Thermodynamic cycles use
factorial perturbations to measure coupling energies bet
239 A 2x2
factorial phase 3 randomized clinical trial among 320 pa
240 In this open-label randomised, two-by-two
factorial phase 3 study in 185 institutions in the USA a
241 ed for screening (full factorial, fractional
factorial,
Plackett-Burman Design) and optimizing (centr
242 +1.414 refer to axial values, -1 and +1 mean
factorial points and 0 refers to centre point of the des
243 Factorial pragmatic randomised trial, analysed by treatm
244 in the two-stratum, open-label, multicentre,
factorial randomised TRACT trial, children aged 2 months
245 Double-blind, placebo-controlled, 2 x 2 x 2
factorial randomized clinical trial among 2157 adults ag
246 NG, AND PARTICIPANTS: This multicenter 2 x 2
factorial randomized clinical trial included overweight
247 aneous assessment of several treatments in a
factorial randomized trial.
248 ble-blind, placebo-controlled, partial 2 x 2
factorial,
randomized clinical trial of vitamin D, calci
249 ion) trial is a multicenter, open-label, 2x2
factorial,
randomized trial of 447 patients with aortic
250 In AUGUSTUS (Open-Label, 2x2
Factorial,
Randomized, Controlled Clinical Trial to Eval
251 A
factorial,
randomized, double-blind, placebo-controlled
252 did genetic and expression data support a co-
factorial relationship, but genomic analysis revealed th
253 ted Holstein heifers (200 kg) were used in a
factorial,
repeated measures experiment with two treatme
254 vestigated the non-linear, synergistic multi-
factorial risk of the UKB envirome on depression using d
255 climate change, as well as the value of full-
factorial screening in predicting biological responses t
256 ata from 2005-2015 and performed a series of
factorial simulation experiments in which seasonal epide
257 er change to seasonal LAI increases based on
factorial simulations from 10 state-of-the-art ecosystem
258 Trend analysis, based on process-model
factorial simulations separating effects of climate, CO2
259 The BMA
factorial simulations suggest that eCO2 provides the gre
260 We here describe f-scLVM (
factorial single-cell latent variable model), a method b
261 a human event-related fMRI study with a two-
factorial stimulus set with 54 images that explicitly di
262 earch could test the generalizability of its
factorial structure in other cultures.
263 This article aims to explore the
factorial structure of the Moral Distress Scale-Revised
264 Principal axis analysis revealed a four-
factorial structure of the RDF items, which mainly resem
265 to explore the Moral Distress Scale-Revised
factorial structure.
266 d to evaluate its psychometric qualities and
factorial structure.
267 A 6 x 2
factorial study was conducted to investigate the effects
268 Each
factorial survey included 3 vignettes, randomly selected
269 Such multi-
factorial systems are difficult to decode in vertebrates
270 le design (CCD, alpha = 1.1) based on a 2(3)
factorial table was used with response surface methodolo
271 The experiment was performed as a
factorial test based on completely randomized design by
272 ponse surface methodology, coupled to a full
factorial three-level experimental design, was applied t
273 d, placebo-controlled, parallel group, 2 x 2
factorial trial (CEQUEL), patients with DSM-IV bipolar d
274 The TRAPEZE trial is a 2 x 2
factorial trial comparing docetaxel alone or with ZA, Sr
275 Randomized, attention-controlled, 2 x 2
factorial trial conducted from February 2009 through Nov
276 We used a 2-by-2
factorial trial design to randomly assign patients who w
277 parallel, open-label, randomised controlled
factorial trial done at 29 centres in the UK.
278 We conducted a cluster-randomized 2 x 2
factorial trial in rural Zimbabwe.
279 We did a cluster randomised 2 x 2
factorial trial in two districts in rural Zimbabwe.
280 a cluster-randomised, community-based, 2 x 2
factorial trial in two rural districts in Zimbabwe.
281 We performed a 2x2
factorial trial of 104 patients with IBS (18-65 years ol
282 ionwide, randomized, placebo-controlled, 2x2
factorial trial of marine n-3 FAs (1 g/d) and vitamin D(
283 dy to CALGB40603, a randomized phase II, 2x2
factorial trial of neoadjuvant paclitaxel +/- carboplati
284 We conducted a 2-by-2
factorial trial of the effects of atorvastatin (80 mg da
285 and August 29, 2014, a randomised 2 x 2 x 3
factorial trial recruited 6- to 23-month-old children wi
286 NSABP B-40 was a 3 x 2
factorial trial testing whether adding capecitabine or g
287 We conducted a randomised 2 x 2 x 3
factorial trial to assess the effectiveness of 12 weeks'
288 METHODS AND In the ARROW
factorial trial, 1,206 children initiating ART in Uganda
289 a randomized and unblinded 2 x 2 sequential-
factorial trial, composed of an induction arm (part 1) c
290 diation Therapy Oncology Group 9413, a 2 x 2
factorial trial, included a random assignment of neoadju
291 In this randomised
factorial trial, participants were recruited from eight
292 In this randomised, 2 x 2
factorial trial, publicly available databases were used
293 In one comparison from a 2-by-2
factorial trial, we randomly assigned 12,705 participant
294 In one comparison from a 2-by-2
factorial trial, we randomly assigned 12,705 participant
295 was a cluster-randomized community-based 2x2
factorial trial.
296 -R-OH has adequate reliability and construct
factorial validity; therefore, it could be a valuable in
297 We tested this hypothesis in a full-
factorial warming (+4 degrees C above ambient) and alter
298 tudy of California grassland exposed to full-
factorial warming, added precipitation, elevated CO2, an
299 Genetically, SSc is multi-
factorial with many genetic risk loci for SSc generally
300 s of schizophrenia is considered to be multi-
factorial,
with likely gene-environment interactions (GE